For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3362 (-)

annotation: Rieske (2Fe-2S) domain protein
coordinates: 587555 - 588841
length: 429

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3362--100% (429)Rieske (2Fe-2S) domain protein
M. thermoresistible (build 8)TH_3877-e-15358.97% (429) PUTATIVE Rieske (2Fe-2S) domain protein
M. thermoresistible (build 8)TH_3820-e-15058.25% (424) PUTATIVE Rieske [2Fe-2S] domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3186c-3e-2230.00% (210) dioxygenase
M. gilvum PYR-GCKMflv_2464-0.087.06% (425) Rieske (2Fe-2S) domain-containing protein
M. tuberculosis H37RvRv3161c-7e-2229.52% (210) dioxygenase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4370c-9e-2133.50% (203) putative large terminal subunit of phenylpropionate dioxygenase
M. marinum MMMAR_4744-1e-15459.05% (420) dioxygenase
M. avium 104MAV_3967-0.088.31% (419) Rieske (2Fe-2S) domain-containing protein
M. smegmatis MC2 155MSMEG_0299-0.085.24% (420) Rieske (2Fe-2S) domain-containing protein
M. ulcerans Agy99MUL_3820-2e-1725.99% (227) ring-hydroxylating dioxygenase, large terminal subunit
M. vanbaalenii PYR-1Mvan_4190-0.087.14% (420) Rieske (2Fe-2S) domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3186c|M.bovis_AF2122/97           --MLSTDNRAELGDILTDIGDYLDDNPPALSLPP---AAYTS---SELWQ
Rv3161c|M.tuberculosis_H37Rv        --MLSTDNRAELGDILTDIGDYLDDNPPALSLPP---AAYTS---SELWQ
TH_3362|M.thermoresistible__bu      -----------MARFPKPPEGSWTEHHPELGTAP---VSYRDCTDPEIYQ
MAV_3967|M.avium_104                -----------MARFPKPPEGSWTQHYPELGTAP---VSYEDSISPEVYE
Mflv_2464|M.gilvum_PYR-GCK          -----------MARFPKPPEGSWTEHYPQLGTGP---VSYEDSIDPEFYE
Mvan_4190|M.vanbaalenii_PYR-1       -----------MARFPKPPEGSWTQHYPQLGTGP---VSYRDSVDPAFYE
MSMEG_0299|M.smegmatis_MC2_155      -----------MARFPKPAEGSWTQHYPELGTGP---VSYEDSISPEIYE
MMAR_4744|M.marinum_M               -----------MPHFTKPAAGSWTQNYPELGTAP---VDYTDSIDPQYFA
MUL_3820|M.ulcerans_Agy99           ------MDRDQLIDLTRRALKLARDKTTDLAPHQ---HAVDAREYTSLDR
MAB_4370c|M.abscessus_ATCC_199      MASLPRPVAVAQGALCRPQALVRDIDVSGLVDSHGGLLDRVIFTDGELYR
                                                  :          . . *                    

Mb3186c|M.bovis_AF2122/97           LER-ERIFNRSWMLVAHVDQLAKTGDYVTVSVAGEPV----MVVRDVDGQ
Rv3161c|M.tuberculosis_H37Rv        LER-ERIFNRSWMLVAHVDQVAKTGDYVTVSVAGEPV----MVVRDVDGQ
TH_3362|M.thermoresistible__bu      KER-HAIFKRAWLNVGRVERLPRKGSYFTKEIKVVNT--SIIVVRTGSGE
MAV_3967|M.avium_104                LER-EAIFKRAWLNVARVEQLPRKGSYLTRELKVVNT--SIILVRNGSGE
Mflv_2464|M.gilvum_PYR-GCK          LER-KAVFRRAWLNVGRVEQVPRKGSYFTKEMKVVNT--SIIVVRTTSGE
Mvan_4190|M.vanbaalenii_PYR-1       LER-KAVFRRAWLNVGRVEQIPRKGSYFTKEMKVVNT--SIIVVRTTTGE
MSMEG_0299|M.smegmatis_MC2_155      LER-QAIFKRAWLNVGRVELLPRKGSYFTKELKAANT--SIIVVRNKSGK
MMAR_4744|M.marinum_M               DEQ-RAIFRRTWLNVGRIERLPRTGSYFTKELPSTGAGMSVIVVKGKDGV
MUL_3820|M.ulcerans_Agy99           HERDRAMVLDSPQLVGYSSELPGPDTYRTKTIMGRSI----LLTRAADRA
MAB_4370c|M.abscessus_ATCC_199      QEL-RRVFAPSWLFLAHADQFHRPGDFFTTYMGEDPV----IVSMDKNRR
                                     *  . :.  :   :.  . .   . : *  :         ::       

Mb3186c|M.bovis_AF2122/97           LHALSPICRHR------LMLMVEPGAGRIDTLTCQYHLWRYGLDGRLRGA
Rv3161c|M.tuberculosis_H37Rv        LHALSPICRHR------LMLMVEPGAGRIDTLTCQYHLWRYGLDGRLRGA
TH_3362|M.thermoresistible__bu      IKAFHNICRHRGNKLVWNDMPLEETSGVCRQFTCKYHAWRYDLDGNLTFV
MAV_3967|M.avium_104                IKAFHNVCRHRGNKLVWNDMPLEETRGVCRQFTCKYHAWRYDLDGNLTFV
Mflv_2464|M.gilvum_PYR-GCK          VKAYHNICRHRGNKLVWNDMPLEETSGVCRQFTCKYHAWRYDLDGNLTFV
Mvan_4190|M.vanbaalenii_PYR-1       VKAYHNICRHRGNKLVWNDMPLEETSGVCRQFTCKYHAWRYDLDGNLTFV
MSMEG_0299|M.smegmatis_MC2_155      INAFHNVCRHRGNKLVWDDLPQQETSGVCRQFTCKYHAWRYDLDGDLTFV
MMAR_4744|M.marinum_M               IRAFHNICRHRGNKLVWNDFPHEETAGTCRQFTCKYHAWRYGLDGELTFI
MUL_3820|M.ulcerans_Agy99           VRAFDNVCLHR-------QSRVATGCGTALRFTCPYHGWTYDNGGRLVGL
MAB_4370c|M.abscessus_ATCC_199      IRAFLNSCRHRG------ARVCRADYGVTRGFTCTYHGWAYDLEGKLISV
                                    :.*    * **               *    :** ** * *.  * *   

Mb3186c|M.bovis_AF2122/97           PHMAANLD-FNRRECRLPQF-AVATWNGLVWINLDAD---AEP-IAAHLD
Rv3161c|M.tuberculosis_H37Rv        PHMAANLD-FNRRECRLPQF-AVATWNGLVWINLDAD---AEP-IAAHLD
TH_3362|M.thermoresistible__bu      QQEEEFFD-LHKSRYGLVPV-HCDVWEGFIFVNFAEQ---PEQSLREFLG
MAV_3967|M.avium_104                QQEEEFFD-LDKSRYGLVPV-HCDVWEGFVFVNFAKT---PEQSLREFLG
Mflv_2464|M.gilvum_PYR-GCK          QQEGEFFD-LDKSRYGLVPV-HCEVWEGFIFVNFAPE---PEQSLREFLG
Mvan_4190|M.vanbaalenii_PYR-1       QQEGEFFD-LDKSRYGLVPV-HCDVWEGFIFVNFAKQ---PEQSLRDFLG
MSMEG_0299|M.smegmatis_MC2_155      QQEEEFFD-LDKSRYGLVPV-HCQVWEGFIFVNFAQE---PEQSLRDFLG
MMAR_4744|M.marinum_M               QQEDEFFD-VDKSQYGLKSV-RCEVWEGFIFINLDP----AAAPLSEYLG
MUL_3820|M.ulcerans_Agy99           PGREGFPG-IAVGSDGLTEL-PATEFAGFLWVSLHPA---ARLDVPAHLG
MAB_4370c|M.abscessus_ATCC_199      PNEEGYPDSFSTDDWGLVEVPHVDSYHGLIFGTWNPAPVGLRESLGDMAW
                                           . .      *  .     : *::: .           :     

Mb3186c|M.bovis_AF2122/97           LTDDEFAGYRLGEMVQVESWSHEWRANWKVAAENGHENYHVLGLHRQT--
Rv3161c|M.tuberculosis_H37Rv        LTDDEFAGYRLGEMVQVESWSHEWRANWKVAAENGHENYHVLGLHRQT--
TH_3362|M.thermoresistible__bu      PMITGLEGYPFDRMTSRFTYRSEVKANWKLYMDAFQEFYHAPVLHANQSP
MAV_3967|M.avium_104                PMITALEGYPFDKMTSRWCYRSEVKANWKLYMDAFQEFYHAPVLHANQSP
Mflv_2464|M.gilvum_PYR-GCK          PMITNLEGYPFDRMTSRFHYRSEVKANWKLYMDAFQEFYHAPVLHANQSP
Mvan_4190|M.vanbaalenii_PYR-1       PMITDLEGYPFDRMTSRFHYRSEVKANWKLYMDAFQEFYHAPVLHANQSP
MSMEG_0299|M.smegmatis_MC2_155      PMITNLEGYPFDKLTSRFTYRSEVKANWKLYMDAFQEFYHAPVLHANQSP
MMAR_4744|M.marinum_M               SMAKGLQGYPFHEMTEVYSYRAEVGSNWKLFIDAFAEFYHAPVLHQGQYT
MUL_3820|M.ulcerans_Agy99           PLAGELQSWGIGRWSPLGEKVLGSPIDWKLATDTFAENYHFATVHRRT--
MAB_4370c|M.abscessus_ATCC_199      YMDAMLDHDSEGTVVVGGVHKWVLDGNWKLAAEQFATDWYHVNMSHASAL
                                         :                    :**:  :     ::   :      

Mb3186c|M.bovis_AF2122/97           -------------LEPFVPGGGDLDVRQYSRWALRLRVPFTVPVEAKS--
Rv3161c|M.tuberculosis_H37Rv        -------------LEPFVPGGGDLDVRQYSRWALRLRVPFTVPVEAKS--
TH_3362|M.thermoresistible__bu      TAYSKAAAEAGFEAPHYRIDGPHRLVSTSGVRAWEMSEEMRKPIEDICRS
MAV_3967|M.avium_104                TAYSKAAAEAGFEAPHYRLDGPHRLVSTSGVRAWEMSPEMRKPIEDICRS
Mflv_2464|M.gilvum_PYR-GCK          TAYSKAAAQAGFEAPHYQIDGPHRLVSTSGVRAWEMADEMRKPIEDICQS
Mvan_4190|M.vanbaalenii_PYR-1       TAYSKAAAEAGFEAPHYRIEGPHRLVSTSGIRAWELADEMRKPIEDICES
MSMEG_0299|M.smegmatis_MC2_155      TAYSRAAAEAGFEAPHYRIEGPHRLVSTSGVRAWEMPDEMRKPIEDICQS
MMAR_4744|M.marinum_M               KEEAAKIMKYGFEALHYELAGPHAMISVWGGQSPPADLKMVKPMDRVLRS
MUL_3820|M.ulcerans_Agy99           ---------------FATIARSNCTVFDSYGPHHRLIFPLNTILELEN--
MAB_4370c|M.abscessus_ATCC_199      MVMAPQGKAP--KDEIVHRTGRQYVDPNGHGAGFPVHPKNRFDARVVHQW
                                                          .                           

Mb3186c|M.bovis_AF2122/97           ---------------------LQLNEVQ-KSN--LVVLWTFPNSALAIAG
Rv3161c|M.tuberculosis_H37Rv        ---------------------LQLNEVQ-KSN--LVVLWTFPNSALAIAG
TH_3362|M.thermoresistible__bu      GLFGPWDKP----DLGEMPKGLNPARCD-PWG--LDSFQLFPNFVILFWG
MAV_3967|M.avium_104                GLFGPWDKP----DLGPMPDGLNPAKCD-PWG--LDSFQLFPNFVILFWG
Mflv_2464|M.gilvum_PYR-GCK          GLFGPWDKP----DLGEMPAGLNPAKCD-PWG--LDSFQLFPNFVILFWG
Mvan_4190|M.vanbaalenii_PYR-1       GLFGPWDKP----DLGEMPVGLNPAKCD-PWG--LDSFQLFPNFVMLFWG
MSMEG_0299|M.smegmatis_MC2_155      GLFGPWDKP----DLGEMPVGLNPAKCD-PWG--LDSFQLFPNFVMLFWG
MMAR_4744|M.marinum_M               GLFGPWDRPAPITDLEELPPGINPTKAK-QWG--IDSFLFFPNFMLLIWE
MUL_3820|M.ulcerans_Agy99           ---------------------VPEGQWD-PFHHMVVIYALFPNVVLSVTI
MAB_4370c|M.abscessus_ATCC_199      TDYGALRER------------LGEARVQGPLTN--GHATVFPNLSYLPVN
                                                         :   . .            ***       

Mb3186c|M.bovis_AF2122/97           -ERVVWFGFIPQSIDRVQVLGGVLTTPELAADAAATAQTSQFVMAMINDE
Rv3161c|M.tuberculosis_H37Rv        -ERVVWFGFIPQSIDRVQVLGGVLTTPELAADAAATAQTSQFVMAMINDE
TH_3362|M.thermoresistible__bu      QGWYLTYHYWPTSYNTHVFEGNLYFPAARTPRERVAQELAAASFKEYGLQ
MAV_3967|M.avium_104                QGWYLTYHYWPTSYHSHVFEGTLYFPAPRTPRERVAQELAAVSFKEYGLQ
Mflv_2464|M.gilvum_PYR-GCK          QGWYLTYHYWPTSHNTHIFEGTVYFPQPRTPRERIAQELAAVSFKEYGLQ
Mvan_4190|M.vanbaalenii_PYR-1       QGWYLTYHYWPTSHNTHLFEGTVYFPQPRTPRERIAQELAAVSFKEYGLQ
MSMEG_0299|M.smegmatis_MC2_155      QGWYLTYHYWPTSYNTHTFECTLYFPQARTPRERLAQELAAASFKEYGLQ
MMAR_4744|M.marinum_M               PGWYLTYHYWPTTVDKHIFETTLYFVPPRNARERLAQELAAVTFKEYALQ
MUL_3820|M.ulcerans_Agy99           ANGELFRIYPGDRPGSSITVHQNSTPLDLSDESVATGAQAVFDYAHATVR
MAB_4370c|M.abscessus_ATCC_199      GSVRIWHPKGPDKMEVWAWTIVDRSMPEEVRDAQRLYNLRTFGPTGIFEQ
                                        :                                            .

Mb3186c|M.bovis_AF2122/97           DR--LGLEAVQVGAGSRFAERGHLSSKEWPGMLAFYRNLAMALVGDHPGA
Rv3161c|M.tuberculosis_H37Rv        DR--LGLEAVQVGAGSRFAERGHLSSKEWPGMLAFYRNLAMALVGDHPGA
TH_3362|M.thermoresistible__bu      DA--NTLEATQSMIESGVLDDFVLCDQ--EVLIRHLHKETADWIDRYERE
MAV_3967|M.avium_104                DA--NTLEATQTMLESRVVDKFVLNDQ--EILLRHLHKETAAWIDDYRRM
Mflv_2464|M.gilvum_PYR-GCK          DA--NTLEATQSMVESRVLDDFVLCDQ--EVLIRHLHTETAAWVDDYRRK
Mvan_4190|M.vanbaalenii_PYR-1       DA--NTLEATQSMVESEVLDEFVLCDQ--EVLIRHLHTETAAWVDEYRRK
MSMEG_0299|M.smegmatis_MC2_155      DA--NTLEATQSMIETRVVEEFLLCDQ--EILLRHLHSETAAWIEDYQRK
MMAR_4744|M.marinum_M               DS--NTLEATQTMIGTGVVKDFPLCDQ--EILLRHLHKMTGDYVKEYRNN
MUL_3820|M.ulcerans_Agy99           DEDYRLAETLQTNLESGARQRLVFGRN-----EPGLQHRHITWAQALETP
MAB_4370c|M.abscessus_ATCC_199      DDG-ENWSEVQSISRGFVTNSVALNYQMGLDSEREDGRHPGLTSELYSDA
                                    *      .  *        .   :  :                       

Mb3186c|M.bovis_AF2122/97           S----------------------
Rv3161c|M.tuberculosis_H37Rv        S----------------------
TH_3362|M.thermoresistible__bu      STGTAAGVAGR------------
MAV_3967|M.avium_104                ST---AGV---------------
Mflv_2464|M.gilvum_PYR-GCK          TQQVKEGV---------------
Mvan_4190|M.vanbaalenii_PYR-1       TAGV-------------------
MSMEG_0299|M.smegmatis_MC2_155      TAGV-------------------
MMAR_4744|M.marinum_M               GHAK-------------------
MUL_3820|M.ulcerans_Agy99           G----------------------
MAB_4370c|M.abscessus_ATCC_199      AGRSFYARWRDLMNTKAWHEEHV