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M. thermoresistible (build 8) TH_3797 (-)

annotation: virulence factor Mce family protein
coordinates: 369706 - 371010
length: 435

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3797--100% (435)virulence factor Mce family protein
M. thermoresistible (build 8)TH_4580-e-14961.47% (423) PUTATIVE putative transcriptional regulator, AraC family
M. thermoresistible (build 8)TH_3918-e-14559.76% (425) PUTATIVE virulence factor Mce family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0607mce2Da2e-8439.25% (400) hypothetical protein Mb0607
M. gilvum PYR-GCKMflv_2104-1e-15361.56% (437) virulence factor Mce family protein
M. tuberculosis H37RvRv1969mce3D1e-15060.65% (432) MCE-family protein MCE3D
M. leprae Br4923MLBr_02592mce1D2e-7938.35% (399) putative secreted protein
M. abscessus ATCC 19977MAB_4150c-3e-7335.08% (439) MCE-family protein
M. marinum MMMAR_4054mce3D_11e-15260.59% (439) MCE-family protein Mce3D_1
M. avium 104MAV_2535-1e-15362.19% (439) virulence factor mce family protein
M. smegmatis MC2 155MSMEG_0349-1e-14759.44% (429) virulence factor mce family protein
M. ulcerans Agy99MUL_3921mce3D_11e-15260.82% (439) MCE-family protein Mce3D_1
M. vanbaalenii PYR-1Mvan_3979-1e-15762.41% (431) virulence factor Mce family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0607|M.bovis_AF2122/97            MSTIFDIRSLRLPKLSAKVVVVGGLVVVLAVVAAAAGARLYRKLTTTTVV
MLBr_02592|M.leprae_Br4923          MSTIFDVRKLKLLRLSRAPVIVGSLVVVLALVVGFVGWRLYQKLTNNTVV
Rv1969|M.tuberculosis_H37Rv         ---------MTTKLRRAR-SVLATALVL--VAGVILAMRTADAAARTTVV
Mvan_3979|M.vanbaalenii_PYR-1       ---------MSARLRRAR-GGLAAVLVLTLAAGFLVAARAADHVERIWVT
MSMEG_0349|M.smegmatis_MC2_155      -----------MRISKKQ-LTLAAGLVVVMVAGVLVGFRMTGPAARTTIT
TH_3797|M.thermoresistible__bu      ----------VTQLNRHRNIALAAVLVLTLVAGMIILVRMYAASDRVQYT
MMAR_4054|M.marinum_M               ------------MIRRTK-TWLAVLLVGLLAAGVVVLLRTTEVVNRTNVV
MUL_3921|M.ulcerans_Agy99           ------------MIRRTK-TWLAVLLVGLLAAGVVVLLRTTEVVNRTNVV
Mflv_2104|M.gilvum_PYR-GCK          -------------MKNLR-LWVGLVLVALLVVGVALLVRTTDKVNRVNVV
MAV_2535|M.avium_104                ---------------------MAIALTAVLLGGIVTVVRSAAGVGRTTVV
MAB_4150c|M.abscessus_ATCC_199      ------------MTTSKTWLKRGAFAMLSVALVGGLLYWVWPSRGTYKIV
                                                          .                          .

Mb0607|M.bovis_AF2122/97            AYFSEALALYPGDKVQIMGVRVGSIDKIEPAGDKMRVTLHYSNKYQVPAT
MLBr_02592|M.leprae_Br4923          VYFPAATALYTGDKVQIMGLRVGSIDSIVPAGDKMKVTFHYQNKYKVPAN
Rv1969|M.tuberculosis_H37Rv         AYFDNSNGVFAGDDVLIRGVPVGKIVKIEPQPLRAKISFWFDRKYRVPAD
Mvan_3979|M.vanbaalenii_PYR-1       AYFENSNGLFAGDDVRILGVPVGRVDSIRPEPTRARITFWVDRRYPVPAD
MSMEG_0349|M.smegmatis_MC2_155      AYFANSNGLFAGDDVLILGVPVGKVKEIEPLPERAKVTFWVDKEFQVPAD
TH_3797|M.thermoresistible__bu      AYFENSNGVYPGDEVRILGVPVGQIDTVEPEPDRAKITFWVSEKYRVPAD
MMAR_4054|M.marinum_M               AYFENSNGVFTGDEVRILGVPVGKITSIEPQPESVKVSFWYDSKYKVPAD
MUL_3921|M.ulcerans_Agy99           AYFENSNGVFTGDEVRILGVPVGKITSIEPQPESVRVSFWYDSKYIVPAD
Mflv_2104|M.gilvum_PYR-GCK          AYFENSNGIYEGDDVRILGVPVGRITSIEPEPERVKISFWYDDRYDVPAD
MAV_2535|M.avium_104                GYFANSTGLYNGDSVVILGVPVGKIEKIEPEPDRVRITFWLNDKYKVPAD
MAB_4150c|M.abscessus_ATCC_199      GHFASAVGLYPGDDVRILGVKAGRISAVEPREGDVKVTMEMPDKFKVPEG
                                     :*  : .:: **.* * *: .* :  : *     ::::    .: **  

Mb0607|M.bovis_AF2122/97            ATASILNPSLVASRTIQLSPPYTGGPVLQDGAVIPIERTQVPVEWDQLRD
MLBr_02592|M.leprae_Br4923          ASAVILNPTLVASRSIQLEPPYKGGPALGDNAVIPLERTQVPVEWDELRD
Rv1969|M.tuberculosis_H37Rv         AAAAILSPQLVTGRAIQLTPPYAGGPTMADGTVIPQERTVVPVEWDDLRA
Mvan_3979|M.vanbaalenii_PYR-1       AKAVILSPQLVTGRAIQLTPAYTGGPVMPTGTVVGQERTAVPVEWDDVRV
MSMEG_0349|M.smegmatis_MC2_155      ATAAILSPQLVTGRAIQLTPPYESGPELPDDAVIPIERTAVPVSWDDFRV
TH_3797|M.thermoresistible__bu      VRAVILSPQLVTARSIELTPAYTGGPTLQPGEVIPEDRTAVPVEWDDLRE
MMAR_4054|M.marinum_M               AKAAILSPTLVTSRAIQLTPAYTGGPAMSDNAVIPRQRTAVPVEWDDVRA
MUL_3921|M.ulcerans_Agy99           AKAAILSPTLVTSRAIQLTPAYTGGPAMSDNAVIPRQRTAVPVEWDDVRA
Mflv_2104|M.gilvum_PYR-GCK          AAAAILSPALVTARAIQLTPVYTGGPVLGDNAVIPLQRTVVPVEWDQVRA
MAV_2535|M.avium_104                VKAAILSPSLVTPRSIQLTPAYTGGPALADHAVIPQQRTAVPVEYDDFRQ
MAB_4150c|M.abscessus_ATCC_199      AQAIIMAPNLVTARFVQLTPAYTDGKALQDGASLGLDKTAVPIEWDEVKT
                                    . * *: * **: * ::* * * .*  :     :  ::* **:.:*:.: 

Mb0607|M.bovis_AF2122/97            SINGILRQLGPTERQPKGPFGDLIESAADNLAGKGRQLNETLNSLSQALT
MLBr_02592|M.leprae_Br4923          SITKIISKLGPTKEQPKGPFGDVIESFADGLAGKGKQINATLDSLSRALT
Rv1969|M.tuberculosis_H37Rv         QLQRLTALLQPTRPGGVSTLGALINTAADNLRGQGATIRDTIIKLSQAIS
Mvan_3979|M.vanbaalenii_PYR-1       QLQRLTKLLRPTEPGGVSTLGAFINTTADNLRGQGANIRQTVVKLSQALA
MSMEG_0349|M.smegmatis_MC2_155      QLEKLTRTLQPETPGGTSALGNFINTAADNLRGEGDNIRDALVKLSKTVT
TH_3797|M.thermoresistible__bu      QLEKLTDALQPTEPGGVSTLGEFINTSAENLRGQGTDIRETVIKLSQAIS
MMAR_4054|M.marinum_M               QLAKLTKELQPTEPGGVSPLGSVINTAADNLRGEGANIRDTVIKLSQAFS
MUL_3921|M.ulcerans_Agy99           QLAKLTKELQPTEPGGVSPLGSVINTAADNLRGEGANIRDTVIKLSQAFS
Mflv_2104|M.gilvum_PYR-GCK          QLERLSETLQPTEPGGVSPLGSVINTTAENLRGQGADIRETVIKLSQAFS
MAV_2535|M.avium_104                QLEKLTQVLQPTAPGGTSTLGAFINTAADNLRGQGPDIRKTVIELSQAIS
MAB_4150c|M.abscessus_ATCC_199      ELAKLSDSLGPQG-QSKGPVSDFINQAATTFDGNGDSFRNAVRELSQAAG
                                    .:  :   * *      .... .*:  *  : *:*  :. :: .**::  

Mb0607|M.bovis_AF2122/97            ALNEGRGDFVAITRSLALFVSALYQNDQQFVALNENLAEFTDWFTKSDHD
MLBr_02592|M.leprae_Br4923          ALNEGRGDFFAVLRSLALFVNALHTDDQQFVALNQNLADFTTRLAHSDTD
Rv1969|M.tuberculosis_H37Rv         ALGDHSKDIFSTVTNLSTLVTALHDSADLLERLNHNLAAVTSLLADGPDK
Mvan_3979|M.vanbaalenii_PYR-1       ILGDHSDDIFTTFTNLSTLVSALHDSADLLEQLNQNMAAVTSLIADDPQK
MSMEG_0349|M.smegmatis_MC2_155      TVSDHKDDVFSTLNNLATLVSALRDSTDVLAALNRNMAAVSALLADSPDE
TH_3797|M.thermoresistible__bu      ILGDHSDDLFTSIKNVSLLVSALHDSTDLLRQLNANLAQATGLLTNGPNE
MMAR_4054|M.marinum_M               ALGDHSTDIFSTVKNLAILVSALQDSTNFMRQLNQNLATVTGLLANDPNE
MUL_3921|M.ulcerans_Agy99           ALGDHSTDIFSTVKNLAILVSALQDSTNLMRQLNQNLATVTGLLANDPNE
Mflv_2104|M.gilvum_PYR-GCK          ALGDRSTDIFSTIKNLAILVSALQDSTDLMRQLNQNLASVSGLLTDGPDE
MAV_2535|M.avium_104                ALGDHSNDLFSTVKNLSILVSALHDSSDLLQQLNQNLAEVTGLLANDPNE
MAB_4150c|M.abscessus_ATCC_199      RLGDSRTDLFGTIKNLQTLVDALANSNEQIVQFSTHLASVSKVLAASTEN
                                     :.:   *..    .:  :* **  . : :  :. ::*  :  :: .  .

Mb0607|M.bovis_AF2122/97            LADTVERIDDVLGTVRKFVSDNRSVLAADVNNLADATTTLVQPEPRDGLE
MLBr_02592|M.leprae_Br4923          LSSALQQFNSMLSTVQSFLVKNREVLAADVNNLATVNNTVVQPEPLNGVE
Rv1969|M.tuberculosis_H37Rv         IGQAAEDLNAVVADVGSFAAEHREAIGTASDKLASITTALVDS--LDDIK
Mvan_3979|M.vanbaalenii_PYR-1       VARTVQDLGGVIGDVKEFADDNREAIGTATDTLASVSTALVDS--LDDLK
MSMEG_0349|M.smegmatis_MC2_155      VGQAIADLNSLAVDVKSFVVENRDAVGTTSDVSASISTALVQS--LDDIK
TH_3797|M.thermoresistible__bu      VGQALADLDAAVRDVTDFVADNREAVGTTTNRLASITSALDES--VEEVK
MMAR_4054|M.marinum_M               VANAVRNLGDTVGEVQRFVADNREALGTTSDKLAGVSQALNDS--LDDVK
MUL_3921|M.ulcerans_Agy99           VANAVRNLGDTVGEVQRFVADNREALGTTSDKLAGVSQALNDS--LDDVK
Mflv_2104|M.gilvum_PYR-GCK          VANAIRDLNAAVGDVQSFVAENRESLGTTSDKLAGVTTALTES--LEDIK
MAV_2535|M.avium_104                VANAVRNLNDVVGDVRGFVAENRDALGTTSDKLASVTQAVTDS--LGDVK
MAB_4150c|M.abscessus_ATCC_199      LGATLGALNQALTDVRGFLGDTNSALIDQVNKLSDFVKIFSDQ--SDDLE
                                    :. :   :.     *  *  . .. :    :  :     . :      ::

Mb0607|M.bovis_AF2122/97            TALHVLPTYASNFNNLYYPLHSSLVGQFVFPNFANPIQLICS-AIQAGSR
MLBr_02592|M.leprae_Br4923          TFLHVAPTAAANMNQLYHPAHGSVVGVPTITNFANPMQFICS-AIQAGSR
Rv1969|M.tuberculosis_H37Rv         QTLHISPTVLQNFNNIFEPANGALTGALAGNNMANPIAFLCG-AIQAASR
Mvan_3979|M.vanbaalenii_PYR-1       QTLHIAPGTVANFHNIFEPANGSLTGALAVNNFANPISFICG-AIQAASR
MSMEG_0349|M.smegmatis_MC2_155      QSLHIFPTTLANFGNIYEPANGSLTGALAINNFSDPISFICG-AIEAASR
TH_3797|M.thermoresistible__bu      QALHIAPNTLANFYNIYQPAQAALTGALAVNNFADPVSFLCG-AIQAASR
MMAR_4054|M.marinum_M               QFLHVAPNTLQNYVNIWQPAQGAVSAVPMLNNFANPISFLCG-AIQAASR
MUL_3921|M.ulcerans_Agy99           QFLHVAPNTLQNYVNIWQPAQGAVSAVPMLNNFANPISFLCG-AIQAASR
Mflv_2104|M.gilvum_PYR-GCK          QFLHVAPSTFQNYINIWQPAQGAVSSVPQINNFANPIQFLCG-AVQAASR
MAV_2535|M.avium_104                QLLHTAPTAFQNFLNIYQPAQGTLTGALAFNNFANTIQFLCG-AVEAASR
MAB_4150c|M.abscessus_ATCC_199      QILHVAPNGLANFYNIYNPAAGTLNGMLSIPNLANPVQFICGGVFETGTK
                                      **  *    *  ::: *  .:: .     *:::.: ::*. ..::.::

Mb0607|M.bovis_AF2122/97            LGYQESAELCAQYLAPVLDALKFNYLPFGSNPFSSAATLPKEVAYSEERL
MLBr_02592|M.leprae_Br4923          LGYQESAELCAQYLSPVLDAIKFNYFPFGLNLFSTAEVLPKEVAYSEARL
Rv1969|M.tuberculosis_H37Rv         LGGEQAAKLCVQYLAPIVKNRQYNYPPLGANLFVGAQARPNEVTYSEDWL
Mvan_3979|M.vanbaalenii_PYR-1       HGAEQSAKLCAQYLAPIVKNRQYNFPPIGENLLVGTQARPNEVTYSEDWL
MSMEG_0349|M.smegmatis_MC2_155      LGAERSAKLCVQYLAPIVKNRQFNFPPFGENTFVGAQARPNEITFSEDWL
TH_3797|M.thermoresistible__bu      LGAEESSKLCVQYLAPIVKNRQYNFLPFGLNPFVGAAARPNEITYSEDWM
MMAR_4054|M.marinum_M               LGYEQSAKLCVQYLAPIIKNRQYNFLPFGQNLFVGASARPNELTYSEDWL
MUL_3921|M.ulcerans_Agy99           LGYEQSAKLCVQYLAPIIKNRQYNFLPFGQNLFVGASARPNELTYSEDWL
Mflv_2104|M.gilvum_PYR-GCK          LGAEESAKLCVQYLAPIIKNRQYNFPPLGLNQLVGATTRPNELTYSEDWL
MAV_2535|M.avium_104                LGAKESAKLCVQYLAPIIKNRQVNFPPLGENLFVGAAARPNELTYSEDWL
MAB_4150c|M.abscessus_ATCC_199      TEYLKRAEICRERMGPVLRRATFNYAPILLHPINQISAYKGQIIYDTPET
                                        . :::* : :.*::     *: *:  : :    .   :: :.    

Mb0607|M.bovis_AF2122/97            RPPPGYKDTTVP-GIFSRDTPFSHGNHEPGWVVAPGMQGMQVQPFTANML
MLBr_02592|M.leprae_Br4923          QPPSGYKDTTVP-GIWVPDTPLSHRNTQPGWIVAPGMQGQQVGPITAALM
Rv1969|M.tuberculosis_H37Rv         RP-----DYVAP-----------------VADTPPDPAAAVT--------
Mvan_3979|M.vanbaalenii_PYR-1       RP-----DFVPP-----------------AAP-PADQPQAVA--------
MSMEG_0349|M.smegmatis_MC2_155      RP-----DYIPP-----------------AQPVTQDLDPEVLPAEAAPTD
TH_3797|M.thermoresistible__bu      RP-----DYRPM-----------------SLPAPADQSLPAEEP-VVPAV
MMAR_4054|M.marinum_M               RP-----DYIPP-QAIPPQAIPPQQAPPAAAPPAQAPPPAVGPPLPAEAP
MUL_3921|M.ulcerans_Agy99           RP-----DYIPP-QAIP-----PQQAPPAAAPPAQAPPPAVGLPLPAEAP
Mflv_2104|M.gilvum_PYR-GCK          RP-----DYIPPGGPAPAPAAGVPTGDPAGLPPGQGPLLLDAPPGAAEMP
MAV_2535|M.avium_104                RP-----DYVPP-HPDSPPTGDAPAPPAAGATPAEAPPPAADAPPPAQA-
MAB_4150c|M.abscessus_ATCC_199      EAKSQAPREDLVWVRPNGAPPPPKPSPQDLSALMLGPDEVNAPPPPGTEV
                                    ..                                                

Mb0607|M.bovis_AF2122/97            TPESLAELLGGPDIAPPAAGNQLARTAECV--------------------
MLBr_02592|M.leprae_Br4923          TPDSLAELMGGPDIEPIQSNLQTPPGPPTAYDEHPVPPPIGLQASVPIPS
Rv1969|M.tuberculosis_H37Rv         --VDPATGLRG-MMMPPGGGS-----------------------------
Mvan_3979|M.vanbaalenii_PYR-1       --VDPDAGLQG-MMVPAGGGVS----------------------------
MSMEG_0349|M.smegmatis_MC2_155      GSADPSAGLPG-LMIPTEAGS-----------------------------
TH_3797|M.thermoresistible__bu      RAADPSQGLPG-LMIPHGGGR-----------------------------
MMAR_4054|M.marinum_M               ATPDPAAGLRG-IMVPQGVGS-----------------------------
MUL_3921|M.ulcerans_Agy99           ATPDPAAGLRG-IMVPQGVGS-----------------------------
Mflv_2104|M.gilvum_PYR-GCK          VPTNPTDGLHG-MMVPPGGGS-----------------------------
MAV_2535|M.avium_104                APTNPAEGLRG-MMMPPGGGQ-----------------------------
MAB_4150c|M.abscessus_ATCC_199      RPAEPGPVPPGFPVTADDAPPPAIPGAPR---------------------
                                       .      *  : .                                  

Mb0607|M.bovis_AF2122/97            ---------------------------------
MLBr_02592|M.leprae_Br4923          PRPDVVPGPVAPTPSPAANVGDPPLPAELGAGQ
Rv1969|M.tuberculosis_H37Rv         ---------------------------------
Mvan_3979|M.vanbaalenii_PYR-1       ---------------------------------
MSMEG_0349|M.smegmatis_MC2_155      ---------------------------------
TH_3797|M.thermoresistible__bu      ---------------------------------
MMAR_4054|M.marinum_M               ---------------------------------
MUL_3921|M.ulcerans_Agy99           ---------------------------------
Mflv_2104|M.gilvum_PYR-GCK          ---------------------------------
MAV_2535|M.avium_104                ---------------------------------
MAB_4150c|M.abscessus_ATCC_199      ---------------------------------