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ITPDNAIAVVGMAGKFPGANDVSAFWTNLRRGKESIVTLSEQELRDNGVSDKALADPAYVRRAPLLDGID EFDADFFGLPPLAAQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVYGTSSPSGYLLHNLLSHRDPHT VLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVALHLACLSLLSGECDMALAGGS SLCIPHRVGYWHSPGSMVSAVGHCRPFDVRADGTVFGSGVALVALKPLQAAIDASDRIHAVILGSAINND GSMKMGYAAPNPAAQADVIAEAHAVAGIDSSTVSYVETHGTGTPLGDPIEIQGLKTAFEVSQIPRPGPCV LGSVKSNIGHLEVAAGIAGLIKTILCLKNKAIPATLHYTSPNRELRLDQTPFVVQSNYGPWKWDGVRRAG VSSFGVGGTNVHVVLEEASVEASTVAASTGPQVILLSAQTAAALGESREALATVLEKPGAPDLSDVAYTL AGRRKHNITMAAVVRDREHAVTVLRAAEHDNVFVGESGADTGRSAAASITTLGSDRVVFLFPGQGAQHVG MAKGLYDTESVFAEHFDTCSAGFREAMDDLDLHSAIFNGTAIDLERIDRSQPALFTVEYALAKLVESFGV GAGAYIGYSTGEYIAATLAGVFDLETAIKTVSLRARLMHESPPGAMVAVALGPEDITEYLAEYSAKGVEL SAVNDPGNCVVAGPKDQIRAFSQRLDEVGIPVRRVRATHAFHTSSMEPMLREFSEFLSRQQLRVPNTPLL SNLTGTWMSEQQVTDPENWTRQISSTIRFADELDVVLSQSGRVLVEVGPGGSLTGSAMRHPRWSSGHRAV RLMRHPLQNVDDHDTFLRALGELWSAGIEVDWAPQRSVMPHLVSLPGYPFARQRHWVEPRYTIWAQIPGA SSGSPVDSSVDSATVEGVRGGESQTEATLQRIWSQCLGVSSVDRNANFFDLGGDSLMAISISMAAANEGM TITPQDMYEHPTLASLTAAVDASFASSGLAKPPEAAAHPAVPPNIAYFLERGLCDTGRWRVPLILRLDPK IGSDDIRAVLTAVVNHHDVLRLSLVDNDGMWEQHIAATGEFTRLLTQTLPDGVAAGSAEERAVVSSILAE LIASQSDLNEPLTAVQITTAHGGPHYLGLAVHQMVIDDASRQILGTDIITAFGQRLAGEEITLEPVTTGW REWSLRCAALATHPAALDTRSFWIENANKVNLWLADVSLNTDVIQPPGADDLIRMPCTLSVEQTSELDDA RRRFRRSIQAIVLAALGRTIAQTVGDGVVAVELEGEGRSVLRPDVDVRRTIGWFTNYYPIPLVCVKGQGA LAQLDAVHNTLKSIPHYGIGYGLLRYMYAPTGRVFSAQRTPDIHFRYVGVVPEPPSVDATVQFDSDMTIP VQEPVPGMGHAIELRTYRFGGSLHLDWWYDIRRIPQVTAEALAQSFPVTLSKLIQEGIATQKDAHDESEM AGAPQAGVLVDLSTLDAG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. leprae Br4923 | MLBr_02353 | - | - | 100% (1489) | polyketide synthase |
M. leprae Br4923 | MLBr_00135 | - | e-123 | 34.91% (928) | putative polyketide synthase |
M. leprae Br4923 | MLBr_02354 | - | e-120 | 35.08% (915) | polyketide synthase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2960 | ppsE | 0.0 | 82.02% (1496) | phenolpthiocerol synthesis type-I polyketide synthase PPSE |
M. gilvum PYR-GCK | Mflv_3390 | - | 0.0 | 55.94% (1498) | beta-ketoacyl synthase |
M. tuberculosis H37Rv | Rv2935 | ppsE | 0.0 | 81.95% (1496) | phenolpthiocerol synthesis type-I polyketide synthase PPSE |
M. abscessus ATCC 19977 | MAB_2256 | - | 0.0 | 39.33% (1012) | polyketide synthase |
M. marinum M | MMAR_1772 | ppsE | 0.0 | 78.63% (1493) | phenolpthiocerol synthesis type-I polyketide synthase PpsE |
M. avium 104 | MAV_1763 | - | 1e-136 | 34.60% (951) | tylactone synthase modules 4 & 5 |
M. smegmatis MC2 155 | MSMEG_0408 | - | 1e-139 | 35.38% (944) | type I modular polyketide synthase |
M. thermoresistible (build 8) | TH_4621 | - | 1e-118 | 34.71% (896) | PUTATIVE mycocerosic acid synthase |
M. ulcerans Agy99 | MUL_2015 | ppsE | 0.0 | 78.23% (1493) | phenolpthiocerol synthesis type-I polyketide synthase PpsE |
M. vanbaalenii PYR-1 | Mvan_3123 | - | 0.0 | 56.73% (1486) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 MSTVEGLRDPASSFAIVGYAARFPGAADADEFWRVLAEGRDAVSEVPKDR MSMEG_0408|M.smegmatis_MC2_155 MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDR TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 WDADEFFDPDPDAPGKVVTRRAGFVDDVTGFDAPFFGMSAREARLLDPQH MSMEG_0408|M.smegmatis_MC2_155 WDIEEFFDPDPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQH TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 RLLLETAWRAVEHSGTAPTDLANTNTGVFIGISTHDYLGMASDELTYDQI MSMEG_0408|M.smegmatis_MC2_155 RILMETAWRAVEHSGIAPTSLANSNTGVFVGLATHDYLGMASDELTYPEI TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 EAYTAIGTSSAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL MSMEG_0408|M.smegmatis_MC2_155 EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 GECDLALAGGANVLLTPATMITFSQAHMLAPDGRCKTFDAAADGYVRGEG MSMEG_0408|M.smegmatis_MC2_155 NECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 CGVLVVKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA MSMEG_0408|M.smegmatis_MC2_155 CGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 EALQRAGIAPGDVDYLEAHGTGTSLGDPIEVQAAGAVLGAGREASRPLLI MSMEG_0408|M.smegmatis_MC2_155 DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLI TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 GSVKTNIGHLEAAAGIAGVIKVILALEHGMLPQHLHFRDPSPHIPWDRLA MSMEG_0408|M.smegmatis_MC2_155 GSAKTNIGHLEAAAGIAGVIKVVMALENETLPKHLNFETPSPHIPWERLP TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 VQVVKEATAWQRNGRPRVAGVSSFGFAGTNAHVILEEAPDGTGRAAVPPA MSMEG_0408|M.smegmatis_MC2_155 IEVVRETVPWQRNGKPRIAGVSSFGFAGTNAHVILEEAP-AVGTPATTEP TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 AVRPPGQRRFHVLPLSARTPAALVQIAGEYRDWLSAHPDTALADLCLTAG MSMEG_0408|M.smegmatis_MC2_155 VEDP---RRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVSHTAG TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 AGRAHFEHRAALVVDSTGSAGELLAALADDRPAPGLLRGVCEDAPKTAWL MSMEG_0408|M.smegmatis_MC2_155 TARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWL TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 FTGQGSQYAGMARELFDTEPVFAETLTRCATVLADVLEKPLLDVIFDTDD MSMEG_0408|M.smegmatis_MC2_155 FTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADE TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 P--ASEATLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSA MSMEG_0408|M.smegmatis_MC2_155 LDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSA TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 ACVAGVLRVEDGARLIAERGRLFGSLPAGGRMVAAFAAAARVEGLTDEFP MSMEG_0408|M.smegmatis_MC2_155 ACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYP TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 SLSVAAYNGANTVLSGPGQELEQAVARLTAEKVRCDWLDTSHAFHSALLD MSMEG_0408|M.smegmatis_MC2_155 SLSVAAYNGANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLD TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 PILDEFESYANQFDFGPPQRILICNRTGSALGRSVKLDGAYWRRHARQPV MSMEG_0408|M.smegmatis_MC2_155 PILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQPV TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 EFAKSVHTLADLGCKVLLEIGPQPVLTAAALRAWPDPATAPRAIASLRRN MSMEG_0408|M.smegmatis_MC2_155 EFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPT TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 TADHRQITEALAEAYIVGHLPDFGAAVGP-ARKLDLPTYPFQHRQYWFSE MSMEG_0408|M.smegmatis_MC2_155 TADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSD TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 QRVPPGSQQTS-------TQTTAVRLLEDGRIAELAELLDGASADQHTLD MSMEG_0408|M.smegmatis_MC2_155 NRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLR TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 VLTKLAAQHNQQRKSRSIAEDRYEIRWEKSTVPGP--EAEATWLVVGDDD MSMEG_0408|M.smegmatis_MC2_155 VLNKLAARHNQQRSTHVDPDARYEIRWDAIASAAASTGAAADWILVGDDT TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 DAVAPLVDALTARGHQHRILVLPASDADEERLEIVLRAAAAEEAPLRIAL MSMEG_0408|M.smegmatis_MC2_155 AAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGE--LYVVH TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 VAALDSGTAPSMRSLLRMQHRVLAGTRRLFRAAAAAELRQPIWLVTRGAQ MSMEG_0408|M.smegmatis_MC2_155 IAAGDGAAAP-MRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQ TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 RVTDADTVFPDQSCLWGFGRAASLEYPQLWGGLADLAQGSAEEWSRLVRV MSMEG_0408|M.smegmatis_MC2_155 RVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLS-GADTEWPRLIAR TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 ASAPRDPAVGEDQIALRGSDIYVPRLTRRSGQPAAAALTLRADATYLVTG MSMEG_0408|M.smegmatis_MC2_155 ITSPRD---GEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTG TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 GLGSIGLEIAGHLAAQGARHLVLTGRRAPGEAAQRRIDALSQQHGCEVRV MSMEG_0408|M.smegmatis_MC2_155 GLGAIGLEVAGYLASHGAGHVVLTSRREPGDDARRRLDGLREQYACDVRV TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 ----------------------------------------------MQHS MAV_1763|M.avium_104 IAADVADAHHVARLLGAVRAELPPVAGIVHAAGEIGTTPLSDLEDAEIDR MSMEG_0408|M.smegmatis_MC2_155 ITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDR TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 STAAELQRKWLRGGAFEPDRHPALVVFPHAGGGATFYRSWLTNPDFSVHV MAV_1763|M.avium_104 VFAGKVWGAWHLSEAAADLR--LDFFVSTSSIASVWGGLGQTAYGAANAF MSMEG_0408|M.smegmatis_MC2_155 VFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAF TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 VQYPGREDRISEQLPSSLGALADGVAEALLTVGDRPLYLFGHSMGALVAF MAV_1763|M.avium_104 LDGLAWRLREQGVNGISVNFGPWAAGMADENARARLAQRGIKTLSPADAL MSMEG_0408|M.smegmatis_MC2_155 LDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQRGVRTLSPAEAL TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 EVARRLETADRFRQLRLCVSSYTAPHLVRSRGLRDMDDEAFVAYGRSATG MAV_1763|M.avium_104 AGLADVMATAAAQGVVARIDWTRFLPLYQQAGQRSLLAELAREIPDFAP- MSMEG_0408|M.smegmatis_MC2_155 AGMADVVAG-PVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATG TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 EVSAATGEASAFDVTALRDLVVAGLRADFHLVEQYRAEPKPPVDAPILAL MAV_1763|M.avium_104 ---APTPSGKTGLVERLAGAPVQQRRKLMTEFLRNAVAEVTRVDAAEIRE MSMEG_0408|M.smegmatis_MC2_155 AAAPATVPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRD TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 WGDDEAI---------DPADMDLWADVTRGGYRSATFPGGHFYLAAERDA MAV_1763|M.avium_104 DAGFFDLGMDSLMAIELRRHIEQGVGKQIPATLAMDYPRLSDVAEYLLGD MSMEG_0408|M.smegmatis_MC2_155 EAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVE TH_4621|M.thermoresistible__bu ------------------------------VNIVGDTP------------ Mflv_3390|M.gilvum_PYR-GCK -------MTSGTRDSTSDSPQDSLPDNAIAVIGMAGRFPGAQS-VSEFWR Mvan_3123|M.vanbaalenii_PYR-1 -------MTSGASNNT-----DELPDNAIAVIGMAGRFPGAGS-VSEFWR Mb2960|M.bovis_AF2122/97 ---------------------MSIPENAIAVVGMAGRFPGAKD-VSAFWS Rv2935|M.tuberculosis_H37Rv ---------------------MSIPENAIAVVGMAGRFPGAKD-VSAFWS MLBr_02353|M.leprae_Br4923 ---------------------MITPDNAIAVVGMAGKFPGAND-VSAFWT MMAR_1772|M.marinum_M --------------------MSTIPDNAIAVVGMAGKFPGAKD-VSTFWS MUL_2015|M.ulcerans_Agy99 --------------------MSTIPDNAIAVVGMAGKFPGAKD-VSTFWS MAB_2256|M.abscessus_ATCC_1997 VLETVRQWWAELDGESEASEVHEVRDDDVAVIGIAARVPGAAS-LDEFWT MAV_1763|M.avium_104 VLDLRGQPDAKPAPPAGTPAPAGRTDEPIAIVAMACRFPGAAD-PEAFWE MSMEG_0408|M.smegmatis_MC2_155 VLGLGEQTNVRQAS-----TVTARTDDPIAVVAVSCRFPGAPD-PESFWE TH_4621|M.thermoresistible__bu -------------------------VNAVAVIGMACRLPGGIDSPQRLWE : :*::.:: :.**. . . :* Mflv_3390|M.gilvum_PYR-GCK NLRGGVESIVDLSESELLAAGVTEQTLANR--SYVRRAALMSGIEEFDAD Mvan_3123|M.vanbaalenii_PYR-1 NLRNGVESIVDLPEDELLANGVTERTLSNR--SYVRRAGLMPGIDEFDAD Mb2960|M.bovis_AF2122/97 NLRRGKESIVTLSEQELRDAGVSDKTLADP--AYVRRAPLLDGIDEFDAG Rv2935|M.tuberculosis_H37Rv NLRRGKESIVTLSEQELRDAGVSDKTLADP--AYVRRAPLLDGIDEFDAG MLBr_02353|M.leprae_Br4923 NLRRGKESIVTLSEQELRDNGVSDKALADP--AYVRRAPLLDGIDEFDAD MMAR_1772|M.marinum_M NLRRGKESIVTLSEEELREAGVSDKTLADP--SYVRRAPLVDGIDEFDAD MUL_2015|M.ulcerans_Agy99 NLRRGKESIVTLSEEELREAGVSDKTLADP--SYVRRAPLVDGIDEFDAD MAB_2256|M.abscessus_ATCC_1997 NLCAGEESLTRFTDEELLSAGVTPEELRDP--RLVRVRPILADVADFDTK MAV_1763|M.avium_104 LLSGGVDAIREVPEDRFDIDEFYDPDPETPGKMYSRFGGYLDQIDEFDPE MSMEG_0408|M.smegmatis_MC2_155 LLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRFGGFLDGIDGFDPE TH_4621|M.thermoresistible__bu ALLRGDDMVTEIPVDRWDADDYFDPEPGVPGRTVSRWGAFLDDVAGFDPE * * : : .. .. * : : **. Mflv_3390|M.gilvum_PYR-GCK FFGFTPQAAKALDPQHRLFLQTVFHAFEDAGYDPKGLEATVGVFGTSSTS Mvan_3123|M.vanbaalenii_PYR-1 FFGFTPYAARMLDPQHRLFLQTVFHAMEDAGYDPKGLEATVGVFGTSSSS Mb2960|M.bovis_AF2122/97 FFGFPPLAAQVLDPQHRLFLQCAWHALEDAGADPARFDGSIGVYGTSSPS Rv2935|M.tuberculosis_H37Rv FFGFPPLAAQVLDPQHRLFLQCAWHALEDAGADPARFDGSIGVYGTSSPS MLBr_02353|M.leprae_Br4923 FFGLPPLAAQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVYGTSSPS MMAR_1772|M.marinum_M FFGFPPLAAQVLDPQHRLFLQCAWHALEDANCDPAKFDGSIGVYGTSSPS MUL_2015|M.ulcerans_Agy99 FFGFPPLAAQVLDPQHRLFLQCAWHALEDANCDPAKFDGSIGVYGTSSPS MAB_2256|M.abscessus_ATCC_1997 FFGYAPSEARSIDPQQRLFLECAWEAVESAGYDLQRYDGSVGVFGGSAGS MAV_1763|M.avium_104 FFGISPREAVWIDPQQRLVLETVWEGLERAGYSPAALRGSR--------- MSMEG_0408|M.smegmatis_MC2_155 FFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSR--------- TH_4621|M.thermoresistible__bu FFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSS--------- *** . * ::**:**.*: :...* *. .: Mflv_3390|M.gilvum_PYR-GCK GYLLHNLMSNYDPMMVIGQGASFDMVSLSLSNDKDHLATRVAHSYDLRGP Mvan_3123|M.vanbaalenii_PYR-1 GYLLHNLMSNFDPMMVIGQGASFEMVNLSLQNDKDHLATRAAHQFDFRGP Mb2960|M.bovis_AF2122/97 GYLLHNLLSHRDPNAVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGP Rv2935|M.tuberculosis_H37Rv GYLLHNLLSHRDPNAVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGP MLBr_02353|M.leprae_Br4923 GYLLHNLLSHRDPHTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGP MMAR_1772|M.marinum_M GYLLHNLLSHRDPNTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGP MUL_2015|M.ulcerans_Agy99 GYLLHNLLSHRDPNTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGP MAB_2256|M.abscessus_ATCC_1997 TYYRAVLSTDYG------NLNGTEYLQTALATENDFLAPRVSYKLNLRGP MAV_1763|M.avium_104 SGIFVGVGANEYSHLLSAESVDKIEPHFITGNALNAISGRVAFALGLEGP MSMEG_0408|M.smegmatis_MC2_155 TGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGP TH_4621|M.thermoresistible__bu TGVFVGLSHDDYA-LLTSDAGALEEAYGFTGSAFSMASGRIAYRLGVHGP : . : . . : * :. ...** Mflv_3390|M.gilvum_PYR-GCK ALSVATACSSSLVAVHLACQSILNGECDIALAGGSSLRIPNRVGYWYAQG Mvan_3123|M.vanbaalenii_PYR-1 ALSVATACSSSLVAVHLACQSLLNGECDIALAGGSSLRIPHHVGYWYEQG Mb2960|M.bovis_AF2122/97 SIAVQTACSSSLVAVHLACLSLLSGECDMALAGGSSLCIPHRVGYFTSPG Rv2935|M.tuberculosis_H37Rv SIAVQTACSSSLVAVHLACLSLLSGECDMALAGGSSLCIPHRVGYFTSPG MLBr_02353|M.leprae_Br4923 SIAVQTACSSSLVALHLACLSLLSGECDMALAGGSSLCIPHRVGYWHSPG MMAR_1772|M.marinum_M SIAVQTACSSSLVAVHLACLSLLSGECDVALAGGSSLCVPHHVGYFTSPG MUL_2015|M.ulcerans_Agy99 SIAVQTACSSSLVAVHLACLSLLSGECDVALAGGSSLCVPHHVGYFTSPG MAB_2256|M.abscessus_ATCC_1997 SISLGTGCSTSLVAIHLAVQSVLTGESDMALAGGASITFPQTAGYVATES MAV_1763|M.avium_104 AVAVDTACSSSLVAVHQACQALHSGDCDLALAGGVNVLLSPVSNIAASRA MSMEG_0408|M.smegmatis_MC2_155 AVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRA TH_4621|M.thermoresistible__bu AVTVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGL :::: *.**::*:*:* * :: *:.*:***** : . Mflv_3390|M.gilvum_PYR-GCK SMVTPTGQCRPFDVRADGTVFGSGVGVLVLKALEDAVADGDRIHAVIRGS Mvan_3123|M.vanbaalenii_PYR-1 AMVSPTGQCRPFDVRSDGTIFASGVGVVVLKALADAIDDGDHIHAVIRGS Mb2960|M.bovis_AF2122/97 SMVSAVGHCRPFDVRADGTVFGSGVGLVVLKPLAAAIDAGDRIHAVIRGS Rv2935|M.tuberculosis_H37Rv SMVSAVGHCRPFDVRADGTVFGSGVGLVVLKPLAAAIDAGDRIHAVIRGS MLBr_02353|M.leprae_Br4923 SMVSAVGHCRPFDVRADGTVFGSGVALVALKPLQAAIDASDRIHAVILGS MMAR_1772|M.marinum_M SMVSAVGHCRPFDVRSDGTVFGSGVAMVVLKPLQAAIDAGDRIHAVIRGS MUL_2015|M.ulcerans_Agy99 SMVSAVGHCRPFDVRSDGTVFGSGAAMVVLKPLQAAIDAGDRIHAVIRAS MAB_2256|M.abscessus_ATCC_1997 GAISTSGRCRAFDASADGTLVGDGIGIVLLKRASNAVADGDSILGIIRGT MAV_1763|M.avium_104 RMLSPVGRCKTFDATADGYVRSEGCGILVLKRMSDAVRDGDRVCAVIPAS MSMEG_0408|M.smegmatis_MC2_155 RMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPAS TH_4621|M.thermoresistible__bu GMLSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGT ::. *:*:.**. :** : ..* :: ** *: .* : .:: .: Mflv_3390|M.gilvum_PYR-GCK ALNNDGATKMTYAAPNALGQAEVIAEAHAIAGVDASTITYVETHGTGTPL Mvan_3123|M.vanbaalenii_PYR-1 ALNNDGSTKMTYAAPNALGQAEVIAEAHAIAGVDASSITYVETHGTGTPL Mb2960|M.bovis_AF2122/97 AINNDGSAKMGYAAPNPAAQADVIAEAHAVSGIDSSTVSYVECHGTGTPL Rv2935|M.tuberculosis_H37Rv AINNDGSAKMGYAAPNPAAQADVIAEAHAVSGIDSSTVSYVECHGTGTPL MLBr_02353|M.leprae_Br4923 AINNDGSMKMGYAAPNPAAQADVIAEAHAVAGIDSSTVSYVETHGTGTPL MMAR_1772|M.marinum_M AINNDGSAKMGYAAPNPAAQADVIAEAHAVSGIDASTVSYVECHGTGTPL MUL_2015|M.ulcerans_Agy99 AINNDGSAKMGYAAPNPAAQADVIAEAHAVSGIDASTVSYVECHGTGTPL MAB_2256|M.abscessus_ATCC_1997 AVNNDGGNKAGFAAPSISGQVEVITEALAVAEVPAQTVDYVETHGTGTPL MAV_1763|M.avium_104 AVNQDGASSG-LTVPNGGAQQRLIATALSRAGLSGDDVDYLEAHGTGTAL MSMEG_0408|M.smegmatis_MC2_155 SVNQDGASSG-LTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPL TH_4621|M.thermoresistible__bu AANQDGRTEN-ISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPV : *:** . :.*. .* : : : : : : :* *****.: Mflv_3390|M.gilvum_PYR-GCK GDPIEVEGLRQAFELAEDERSAPCYLGSVKSNIGHLETAAGIAGLIKAIL Mvan_3123|M.vanbaalenii_PYR-1 GDPIEIEGLRQAFELSEETRSAPCYLGSVKSNIGHLETAAGIAGLIKAIL Mb2960|M.bovis_AF2122/97 GDPIEIQGLRAAFEVSQTSRSAPCVLGSVKSNIGHLEVAAGIAGLIKTIL Rv2935|M.tuberculosis_H37Rv GDPIEIQGLRAAFEVSQTSRSAPCVLGSVKSNIGHLEVAAGIAGLIKTIL MLBr_02353|M.leprae_Br4923 GDPIEIQGLKTAFEVSQIPRPGPCVLGSVKSNIGHLEVAAGIAGLIKTIL MMAR_1772|M.marinum_M GDPIEIQGLRTAFEASETTRTGPCVLGSVKSNIGHLEVAAGIAGLIKTIL MUL_2015|M.ulcerans_Agy99 GDPIEIQGLRTAFEASETTRTGPCVLGSVKSNIGHLEVAAGIAGLIKTIL MAB_2256|M.abscessus_ATCC_1997 GDPIEIAALHKAFREAGDTRTQACRLGTLKPNIGHTGPASGVLALIKVLL MAV_1763|M.avium_104 GDPIEVQAAGAVYGATRDT-DRPLLIGSVKTNIGHLEAASGVAGLIKVVL MSMEG_0408|M.smegmatis_MC2_155 GDPIEVQAAAAAYGAGRDA-DRPLLMGSVKTNIGHTESASGAAGLIKVVL TH_4621|M.thermoresistible__bu GDPIEYNSLTQVYGKTG-----PCALTSVKTNFGHAESAAGALGMMKAIL ***** . .: . : ::*.*:** *:* .::*.:* Mflv_3390|M.gilvum_PYR-GCK CLEHKAIPATLHYTSPNPELHLDRGPFRVRAQDGPWESDG--IRRAGVSS Mvan_3123|M.vanbaalenii_PYR-1 CLEHKAIPATLHYTSPNPELHLDRGPFRIRSSDGPWESDG--IRRAGVSS Mb2960|M.bovis_AF2122/97 CLKNKALPATLHYTSPNPELRLDQSPFVVQSKYGPWECDG--VRRAGVSS Rv2935|M.tuberculosis_H37Rv CLKNKALPATLHYTSPNPELRLDQSPFVVQSKYGPWECDG--VRRAGVSS MLBr_02353|M.leprae_Br4923 CLKNKAIPATLHYTSPNRELRLDQTPFVVQSNYGPWKWDG--VRRAGVSS MMAR_1772|M.marinum_M CLKNRAIPATLHYTSPNPELRLEQSPFVVQNKYGPWEWDG--VLRAGVSS MUL_2015|M.ulcerans_Agy99 CLKNRAIPATLHYTSPNPELRLEQSPFVVQNKYGPWEWDG--VLRAGVSS MAB_2256|M.abscessus_ATCC_1997 AFQHRMYPPAANFTAPNPQIEFSKSPFYVGTRLRRWNAPGGKPRRAGVSS MAV_1763|M.avium_104 SLQHEMLPQSLHFETPSPHIPWDSLPLRVVDKAVPWQT-NGRPRRAGVSS MSMEG_0408|M.smegmatis_MC2_155 SLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQT-NGRVRRAGVSS TH_4621|M.thermoresistible__bu ALQHGVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVREGCPRRAAVSS .::: * :: .: . : * **.*** Mflv_3390|M.gilvum_PYR-GCK FGVGGTNAHIILEEAP-VAPARAQTS----------SPARPSVLVLSART Mvan_3123|M.vanbaalenii_PYR-1 FGVGGTNAHIVLEEAP-TAPVPAPRS----------G---PQVLVLSART Mb2960|M.bovis_AF2122/97 FGVGGTNAHVVLEEAPAEASEVSAHA----------EPAGPQVILLSAQT Rv2935|M.tuberculosis_H37Rv FGVGGTNAHVVLEEAPAEASEVSAHA----------EPAGPQVILLSAQT MLBr_02353|M.leprae_Br4923 FGVGGTNVHVVLEEASVEASTVAAS-------------TGPQVILLSAQT MMAR_1772|M.marinum_M FGVGGTNAHVVLEEAP----TVPAHD----------EPAGPQVLLLSAQT MUL_2015|M.ulcerans_Agy99 FGVGGTNAHVVLEEAP----TVPAHD----------EPAGPQVLLLSAQT MAB_2256|M.abscessus_ATCC_1997 YSMGGTNAHAVLQEPP---RAELPPK----------SQEGAHLLVLSART MAV_1763|M.avium_104 FGFTGTNAHVLIEEAPQPVTTQDAT---PAAESDARPVD---VLPLSARS MSMEG_0408|M.smegmatis_MC2_155 FGFTGTNAHVLVEEAPPQLHTADAAPVEPAATAEAGTDDSPQVLALSARS TH_4621|M.thermoresistible__bu YGMSGTNVHAVLEQAPEPVQRPEES--------ADTDAAGPLVFALSSTS :.. ***.* ::::.. :: **: : Mflv_3390|M.gilvum_PYR-GCK QEALEDSRATLARELGENA-EISLPDVAYTLGR-RRKEPIRLAAVVRDQA Mvan_3123|M.vanbaalenii_PYR-1 EETLAQSRAALAAELSEVD-EISLPDAAYTLTH-RRKDPVRLAAVVHDQE Mb2960|M.bovis_AF2122/97 AAALGESRTALAAALETQD-GPRLSDVAYTLAR-RRKHNVTMAAVVHDRE Rv2935|M.tuberculosis_H37Rv AAALGESRTALAAALETQD-GPRLSDVAYTLAR-RRKHNVTMAAVVHDRE MLBr_02353|M.leprae_Br4923 AAALGESREALATVLEKPG-APDLSDVAYTLAG-RRKHNITMAAVVRDRE MMAR_1772|M.marinum_M AAALTESRTALAEVLERSD-SPDLSDVAYTLSR-RRKHNVTMAAVVSDRE MUL_2015|M.ulcerans_Agy99 AAALTESRTALAEVLGRSD-SPDLSDVAYTLSR-RRKHNVTMAAVVSDRE MAB_2256|M.abscessus_ATCC_1997 APALEAARKNLAHHLARHP-EQDLAAVAATLRLGRRAFSHRFAAVCADRP MAV_1763|M.avium_104 PEALLALAQRYGEWLHAHP-DADIGDLCFTVGAGRAHFEHRAALVVDSVR MSMEG_0408|M.smegmatis_MC2_155 PEALVELARRYDDWLSATP-GLDIADVCHTAGVGRSHFEYRAALVVDSVE TH_4621|M.thermoresistible__bu AEELRRTAGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVRTTVIADGVE * : . * * : : . Mflv_3390|M.gilvum_PYR-GCK NAATVLSAAETDGATDNVFIGR--------GHPDWDSSATDRIAFLFPGQ Mvan_3123|M.vanbaalenii_PYR-1 NAATVLSAAETD----NVFIGR--------AVPDLQDSA-ERVAFLFPGQ Mb2960|M.bovis_AF2122/97 HAATVLRAAEHD----NVFVGEAAHDGEHGDRADAAPT-SDRVVFLFPGQ Rv2935|M.tuberculosis_H37Rv HAATVLRAAEHD----NVFVGEAAHDGEHGDRADAAPT-SDRVVFLFPGQ MLBr_02353|M.leprae_Br4923 HAVTVLRAAEHD----NVFVGESGADTGRSAAASITTLGSDRVVFLFPGQ MMAR_1772|M.marinum_M EAATALRAADND----SIFVGESVAG-----VADATAAAAERVVFLFPGQ MUL_2015|M.ulcerans_Agy99 EAATALRAADND----SIFVGESVAG-----VADATAAAAERVVFLFPGQ MAB_2256|M.abscessus_ATCC_1997 EALQVLEGTGHAP-----------------FRTGTAADKPRPVVFLFPGQ MAV_1763|M.avium_104 SAREALADLADN--------------RTRPGVARGECTDPPTTAWLFTGQ MSMEG_0408|M.smegmatis_MC2_155 RAREGLAALAEG--------------RTPAGVVRGEHVHRPTTAWLFTGQ TH_4621|M.thermoresistible__bu ALTAGLREVADG--------------DAPYQPAVGMDDKAP--VWVFSGQ * .::*.** Mflv_3390|M.gilvum_PYR-GCK GAQHIGMARGLHDNEPVFARYFDECATAFSDEMG-FDLRAEIFDG----- Mvan_3123|M.vanbaalenii_PYR-1 GAQHVGMARGLYDNEPVFKRHFDECATAFSDDMG-YDLRAEIFDG----- Mb2960|M.bovis_AF2122/97 GAQHVGMAKGLYDTEPVFAQHFDTCAAGFRDETG-IDLHAEVFDG----- Rv2935|M.tuberculosis_H37Rv GAQHVGMAKGLYDTEPVFAQHFDTCAAGFRDETG-IDLHAEVFDG----- MLBr_02353|M.leprae_Br4923 GAQHVGMAKGLYDTESVFAEHFDTCSAGFREAMDDLDLHSAIFNG----- MMAR_1772|M.marinum_M GAQHVGMAKGLYETEPVFAEHFDACAAGFRAEMG-VDLNAEIFNG----- MUL_2015|M.ulcerans_Agy99 GAQHVGMAKGLYETEPVFAEHFDACAAGFRAEMG-VDLNAEIFNG----- MAB_2256|M.abscessus_ATCC_1997 GSQFSGMGEQLYTTSSMYRRHIDECATLFEPLIG-VDLRTMLCAEGDEA- MAV_1763|M.avium_104 GSQYPGMARELFDAEPVFAETVTRCADAVDGLLPRPLTEVIFATDKDTGG MSMEG_0408|M.smegmatis_MC2_155 GSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET-- TH_4621|M.thermoresistible__bu GSQWAGMGAELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTG- *:* **. * . :: . . Mflv_3390|M.gilvum_PYR-GCK -VGRNLEHTDRAQPALFTVEYALARLIQSYGVEPAIMAGHSIGEYPAATL Mvan_3123|M.vanbaalenii_PYR-1 -VGRNLEHTDRAQPALFTVEYALAKLVQSYGVEPAIMAGHSIGEYPAATI Mb2960|M.bovis_AF2122/97 -TATDLERIDRSQPALFTVEYALAKLVDTFGVRAGAYIGYSTGEYIAATL Rv2935|M.tuberculosis_H37Rv -TATDLERIDRSQPALFTVEYALAKLVDTFGVRAGAYIGYSTGEYIAATL MLBr_02353|M.leprae_Br4923 -TAIDLERIDRSQPALFTVEYALAKLVESFGVGAGAYIGYSTGEYIAATL MMAR_1772|M.marinum_M -TATDLERIDRSQPALFTVEYALAKLVDTYGVRAGAYIGYSTGEYIAATL MUL_2015|M.ulcerans_Agy99 -TGTDLERIDRSQPALFTVEYALAKLVDTYGVRAGAYIGYSTGEYIAATL MAB_2256|M.abscessus_ATCC_1997 -TDAALMQTRLTQPALFTVGYALSQLLGAWGVQPVAMLGHSIGELVAACA MAV_1763|M.avium_104 EAGKTLRNTAFAQPALFAVEMGLARLWQSWGVEPDVVLGHSVGQYAAACV MSMEG_0408|M.smegmatis_MC2_155 --ADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACV TH_4621|M.thermoresistible__bu --------IDRVQPTLFAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVV **:**:: .*: ::.: . *:* *: ** Mflv_3390|M.gilvum_PYR-GCK AGVFDLDTAVKVVATRAKLMHAAP-RGVMIAVPLSPDAVAEYLTP----D Mvan_3123|M.vanbaalenii_PYR-1 AGVFDLDTAVKVVSKRAKLMHAAP-RGVMVAVPLSPEAVAEHLTP----D Mb2960|M.bovis_AF2122/97 AGVFDLQTAIKTVSLRARLMHESP-PGAMVAVALGPDDVTQYLPP----E Rv2935|M.tuberculosis_H37Rv AGVFDLQTAIKTVSLRARLMHESP-PGAMVAVALGPDDVTQYLPP----E MLBr_02353|M.leprae_Br4923 AGVFDLETAIKTVSLRARLMHESP-PGAMVAVALGPEDITEYLAEYSAKG MMAR_1772|M.marinum_M AGVFDLETAIKTVSLRARLMHESP-PGAMVAVAVGPDEIAQYLGD----G MUL_2015|M.ulcerans_Agy99 AGVFDLETAIKTVSLRARLMHESP-PGAMVAVAVGPDDFAQYLGD----G MAB_2256|M.abscessus_ATCC_1997 AGVFTIEEAVQLAARRGDLIQQCP-SGAMAAVGGSLEVVSALLPEG---- MAV_1763|M.avium_104 AGVFSLEDGARLMAERGRLFGGLPDGGRMVAVFADAQYVEELANDCPRVS MSMEG_0408|M.smegmatis_MC2_155 AGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVS TH_4621|M.thermoresistible__bu AGALSLEDGVKVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDD **.: :: . : . *. : . * * *: : . Mflv_3390|M.gilvum_PYR-GCK VDIATINDPGSCVVAGTDEAIRAFQAGLAEKGVAARRVRTAHAFHSRLMD Mvan_3123|M.vanbaalenii_PYR-1 VDVATINDPGSCVVAGSEEAIRTFQAALAEKGVAARRVRTSHAFHSRLMD Mb2960|M.bovis_AF2122/97 VELSAVNDPGNCVVAGPKDQIRALRQRLTEAGIPVRRVRATHAFHTSAMD Rv2935|M.tuberculosis_H37Rv VELSAVNDPGNCVVAGPKDQIRALRQRLTEAGIPVRRVRATHAFHTSAMD MLBr_02353|M.leprae_Br4923 VELSAVNDPGNCVVAGPKDQIRAFSQRLDEVGIPVRRVRATHAFHTSSME MMAR_1772|M.marinum_M VELSAVNDPGNCVVAGPKDEIRAFSQRLNEAGIPVRRVRATHAFHSSSME MUL_2015|M.ulcerans_Agy99 VELSAVNDPGNCVVAGPKDEIRAFSQRLNEAGIPVRRVRATHAFHSSSME MAB_2256|M.abscessus_ATCC_1997 VSVAAVNGPEQIVVAGREEGIEALLSTGANVGVRCTRLPVNRGFHSALVD MAV_1763|M.avium_104 VAAYNGPN---TVLSGPGADLEQIVARGASDGIRCSWLETSHAFHSELLD MSMEG_0408|M.smegmatis_MC2_155 VGAYNGPN---TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLD TH_4621|M.thermoresistible__bu VVLSVIASPESTVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVD * . *:.* :. : *: : . . *: :: Mflv_3390|M.gilvum_PYR-GCK PVVAEFTAFLSGLTLREPQIPLLSNVTGTTMSASEATNPSTWARQIRATV Mvan_3123|M.vanbaalenii_PYR-1 PVVAEFGAFLSGVTLREPQIPLLSNITGTTMTAAEATNPSTWARQIRATV Mb2960|M.bovis_AF2122/97 PMLGQFQEFLSRQQLRPPRTPLLSNLTGSWMSDQQVVDPASWTRQISSPI Rv2935|M.tuberculosis_H37Rv PMLGQFQEFLSRQQLRPPRTPLLSNLTGSWMSDQQVVDPASWTRQISSPI MLBr_02353|M.leprae_Br4923 PMLREFSEFLSRQQLRVPNTPLLSNLTGTWMSEQQVTDPENWTRQISSTI MMAR_1772|M.marinum_M PMLGEFQEFLSRQQLRAPQTPLLSNLTGTWLSEQQVTDPATWARQISSTV MUL_2015|M.ulcerans_Agy99 PMLGEFQEFLSRQQLRAPQTPLLSNLTGTWLSEQQVTDPATWARQISSTV MAB_2256|M.abscessus_ATCC_1997 PAVSSFSAAVARMRLQQPQVPFISNVTGTWITGAQATEPEYWGRQLRETV MAV_1763|M.avium_104 PVLDEFESYAAHLDFAVPTLPLVCNRTGTVLTTETPLDARYWRRHSRQPV MSMEG_0408|M.smegmatis_MC2_155 PVLDEFEAYAAQFQFAAPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPV TH_4621|M.thermoresistible__bu PILDELEEILADLQPMTPTVPYYS-ATSYDPREKPVCDADYWVDNLRHEV * : .: : * * . *. :. * : : Mflv_3390|M.gilvum_PYR-GCK RFADELDALLAA-PDRVLVEVGPGGTLTSSAGRHPRWSERHRAVRLMRHQ Mvan_3123|M.vanbaalenii_PYR-1 RFADELDALLAA-PDRVLVEVGPGGTLTSSAGRHPKWTERHRAVRLMRHQ Mb2960|M.bovis_AF2122/97 RFADELDVVLAA-PSRILVEVGPGGSLTGSAMRHPKWSTTHRTVRLMRHP Rv2935|M.tuberculosis_H37Rv RFADELDVVLAA-PSRILVEVGPGGSLTGSAMRHPKWSTTHRTVRLMRHP MLBr_02353|M.leprae_Br4923 RFADELDVVLSQ-SGRVLVEVGPGGSLTGSAMRHPRWSSGHRAVRLMRHP MMAR_1772|M.marinum_M RFADELDVVLSQ-PNRILVEIGPGGSLTGSAIRHPKWSDGHRSVRLMRHP MUL_2015|M.ulcerans_Agy99 RFADELDVVLSQ-PNRILVEIGPGGSLTGSAIRHPKWSDGHRSVRLMRHP MAB_2256|M.abscessus_ATCC_1997 QFARGLTTLCAEYPDALLVEVGPGHTLRGIVAAN---TPASEVVSMLGDR MAV_1763|M.avium_104 QFAESVRTVAAL-GCTVLMEIGPQPVLTG--AAVQVWPEHLAAPRAIVSL MSMEG_0408|M.smegmatis_MC2_155 QFAESVRTVAAL-GCSVLMEIGPQPVLTG--AAVQVWPEHMAAPRAVASL TH_4621|M.thermoresistible__bu RFAAAVQAALED-GFRVFGELSPHPLLTR--AVEQTARGLDMPVAALPAM :** : . :: *:.* * : Mflv_3390|M.gilvum_PYR-GCK AQNRSDDDTFHLALGQLWAADVDVDWTQGDQDAADARTLVTLPGYPFARQ Mvan_3123|M.vanbaalenii_PYR-1 AQNRNDHDTFLLALGQLWAADVEVDFNQG---AEEDRTLITLPGYPFAKQ Mb2960|M.bovis_AF2122/97 LQDVDDRDTFLRALGELWSAGVEVDWTPR---RPAVPHLVSLPGYPFARQ Rv2935|M.tuberculosis_H37Rv LQDVDDRDTFLRALGELWSAGVEVDWTPR---RPAVPHLVSLPGYPFARQ MLBr_02353|M.leprae_Br4923 LQNVDDHDTFLRALGELWSAGIEVDWAPQ---RSVMPHLVSLPGYPFARQ MMAR_1772|M.marinum_M IQNLDDRETFLRALGELWSAGVDVDWTPR---RAASPRIVSLPGYPFARQ MUL_2015|M.ulcerans_Agy99 IQNLDDRETFLRALGELWSAGVDVDWTPR---RAASPRIVSLPGYPFARQ MAB_2256|M.abscessus_ATCC_1997 TG--DSATVALAAAGRLWAGGAELAWQHFG----ASRPRVPLPTYPFERE MAV_1763|M.avium_104 RKGVGDRRQIAEGLAAAYVSGHRPEFAALHR--RPRRK-LELPTYPFQRR MSMEG_0408|M.smegmatis_MC2_155 RKGVADRRQIADALASAYVGGHRPDFAAVHR--QPRRP-VELPTYPFQRR TH_4621|M.thermoresistible__bu RREQEMPHGVRTMVGDLFAAGAAVDFAALYP--SGRLVDAPLPTWTRRKL . : .. : ** :. : Mflv_3390|M.gilvum_PYR-GCK RHWVEYN----ASSAWVANG--SGAAGVSATGAQAGSAAGGAGGGSSVEA Mvan_3123|M.vanbaalenii_PYR-1 RHWVEHN----ANAAWLAGG--AGADGTAAAAGSAGVAPVAAGGTSTVEA Mb2960|M.bovis_AF2122/97 RHWVEPNHTVWAQAPGANNG--SPAGTADGSTA--ATVDAARNGESQTEV Rv2935|M.tuberculosis_H37Rv RHWVEPNHTVWAQAPGANNG--SPAGTADGSTA--ATVDAARNGESQTEV MLBr_02353|M.leprae_Br4923 RHWVEPRYTIWAQIPGASSG--SPVDSSVDS----ATVEGVRGGESQTEA MMAR_1772|M.marinum_M RHWVEPKHMAWAQIPTASNG--SSVGAKLGSGADSGIRGGAQTGESQTED MUL_2015|M.ulcerans_Agy99 RHWVEPKHMAWAQIPTASNG--SSVGAKLGSGADSGIRGGAQTGESQTED MAB_2256|M.abscessus_ATCC_1997 RLWMSPP--------RSVLD--KPVQAPIAPAVQVPLVTASTQTDVPDAA MAV_1763|M.avium_104 RFWPKASGIAGIDGQGAAASGLLGSAKELASGDS--VYTSRLSVKSQPWL MSMEG_0408|M.smegmatis_MC2_155 RFWPKASSIA-VDG-GTAASGILGSGKDLASGDT--IYTSRLSVKSQPWL TH_4621|M.thermoresistible__bu VLSRENGEQQTRGGCTITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWL . Mflv_3390|M.gilvum_PYR-GCK SLQRIWAQCLGVNEIDRHANFFEIG------------------------- Mvan_3123|M.vanbaalenii_PYR-1 KLARIWSQCLGLSDIDRNANFFEIG------------------------- Mb2960|M.bovis_AF2122/97 TLQRIWSQCLGVSSVDRNANFFDLG------------------------- Rv2935|M.tuberculosis_H37Rv TLQRIWSQCLGVSSVDRNANFFDLG------------------------- MLBr_02353|M.leprae_Br4923 TLQRIWSQCLGVSSVDRNANFFDLG------------------------- MMAR_1772|M.marinum_M VLQRIWSQCLGVGSVDRNANFFDMG------------------------- MUL_2015|M.ulcerans_Agy99 VLQRIWSQCLGVGSVDRNANFFDMG------------------------- MAB_2256|M.abscessus_ATCC_1997 VVEQIWCEALGVPSVESDDNFFDLG------------------------- MAV_1763|M.avium_104 ADHVIYGTVVVPGATYAAMALAAVGPPARVQNVYFYEPIILPDKASREVQ MSMEG_0408|M.smegmatis_MC2_155 ADHVIYGTVVVPGATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQ TH_4621|M.thermoresistible__bu ADHQIHTVAALPGAAYCEMALAAAREVIDSDGVEVRD-----VRFEQMLL * : Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 LSLHPLQEG-GWSFRVDSRPYGVPDAEWSLNADGTV-VAGIEDEPAADP- MSMEG_0408|M.smegmatis_MC2_155 LTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQ TH_4621|M.thermoresistible__bu LDEQTEVSAVASAVEPGTLEFAVETAKDGEHERRATAVLGAADDTEPPQA Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------G Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------G Mb2960|M.bovis_AF2122/97 -------------------------------------------------G Rv2935|M.tuberculosis_H37Rv -------------------------------------------------G MLBr_02353|M.leprae_Br4923 -------------------------------------------------G MMAR_1772|M.marinum_M -------------------------------------------------G MUL_2015|M.ulcerans_Agy99 -------------------------------------------------G MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------G MAV_1763|M.avium_104 ADHIDAVIERLDRNRPQLLFDSFAESELEWGTTWSTSLKSLWMGDGEAVG MSMEG_0408|M.smegmatis_MC2_155 SDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVG TH_4621|M.thermoresistible__bu HDIDALLAEHPTRIEGDELRQWFDQRGVQFGPAFTG-LTAARIPEG-TVT Mflv_3390|M.gilvum_PYR-GCK DSLVAISVAMTAGHAGLDLTPQDLYENQTVASLAKVLTARYAEGGLARQS Mvan_3123|M.vanbaalenii_PYR-1 DSLIAISVAMTAGHEGLDLTPQDLYENQTVAALAKVLTARYAEGGLARQT Mb2960|M.bovis_AF2122/97 DSLMAISIAMAAANEGLTITPQDLYEYPTLASLTAAVDASFASSGLAKP- Rv2935|M.tuberculosis_H37Rv DSLMAISIAMAAANEGLTITPQDLYEYPTLASLTAAVDASFASSGLAKP- MLBr_02353|M.leprae_Br4923 DSLMAISISMAAANEGMTITPQDMYEHPTLASLTAAVDASFASSGLAKP- MMAR_1772|M.marinum_M DSLMAISIAMSAANEGLTITPQDLYEHPTLASLTAAIDASFASSGLAKP- MUL_2015|M.ulcerans_Agy99 DSLMAISIAMSAANEGLTITPQDLYEHPTLASLTAAIDASFASSGLAKP- MAB_2256|M.abscessus_ATCC_1997 DSLIAARVVTAIGER-----------CHIKVSVAELWDQGATLADLAELV MAV_1763|M.avium_104 DVTVGDELAEHLGTEPMHPVLLDLCTGVVFPAFPALLAAEQGFNDLLLPL MSMEG_0408|M.smegmatis_MC2_155 DILVGAELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPL TH_4621|M.thermoresistible__bu SVLAEVGLPGQIRSQQAPYGIHPALLDACFQSVAAHPDVQGAGSGLLLPL . : :.. .* Mflv_3390|M.gilvum_PYR-GCK ---------------------VDDSTSPPVPPNVAYFLEHGLRDVGRWRI Mvan_3123|M.vanbaalenii_PYR-1 ---------------------LDDAVNPPVPPNVAYFLEHGLRDIGRWRI Mb2960|M.bovis_AF2122/97 ---------------------PEAQANPAVPPNVTYFLDRGLRDTGRCRV Rv2935|M.tuberculosis_H37Rv ---------------------PEAQANPAVPPNVTYFLDRGLRDTGRCRV MLBr_02353|M.leprae_Br4923 ---------------------PEAAAHPAVPPNIAYFLERGLCDTGRWRV MMAR_1772|M.marinum_M ---------------------PEADANPAVPPNIAYFLDRGLRDTGRWRV MUL_2015|M.ulcerans_Agy99 ---------------------PEADANPAVPPNIAYFLDRGLRDTGRWRV MAB_2256|M.abscessus_ATCC_1997 ---------------------ERRAINSKVGEQLK--------------- MAV_1763|M.avium_104 RYGQVSLREKMPRRFYCRGKWRPSALDSETQVFDIDFIDRDGRHLGGIRE MSMEG_0408|M.smegmatis_MC2_155 RYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIRE TH_4621|M.thermoresistible__bu GVRRLQAFGPTRGARYCYARVT--DADGSKAEADLDVLDEHGNVLLRVQG Mflv_3390|M.gilvum_PYR-GCK PVILGLRSDVGEDDVRAVLTAVTDAHDVLRVRLVERSGIWDQIIAEPGEF Mvan_3123|M.vanbaalenii_PYR-1 PVILGLRSDVGEDDVRAVLTAVTEVHDALRVHLVERAGTWDQHIAEPGEF Mb2960|M.bovis_AF2122/97 PLILRLDPKIGLPDIRAVLTAVVNHHDALRLHLVGNDGIWEQHIAAPAEF Rv2935|M.tuberculosis_H37Rv PLILRLDPKIGLPDIRAVLTAVVNHHDALRLHLVGNDGIWEQHIAAPAEF MLBr_02353|M.leprae_Br4923 PLILRLDPKIGSDDIRAVLTAVVNHHDVLRLSLVDNDGMWEQHIAATGEF MMAR_1772|M.marinum_M PLILRLDPQVGPEDIRAVLSAVTNHHDALRLRLVENGGVWEQHIAAPADF MUL_2015|M.ulcerans_Agy99 PLILRLDPQVGPEDIRAVLSAVTNHHDALRLRLVENGGVWEQHIAAPADF MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 FTVKRAPREALLRGLGGDATRLLYTLGWHEVPPQPSNDG---VANPSGTW MSMEG_0408|M.smegmatis_MC2_155 FTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSAD------DAVGTW TH_4621|M.thermoresistible__bu LLMGGAAADGDDRDRVLGERLLTIEWQRRDLPEADSAAGKWLLVSTSATA Mflv_3390|M.gilvum_PYR-GCK TELASRELPSGVAAGSPQEREAVLAFLDEQVREH-QVVVPLTATLIRSGS Mvan_3123|M.vanbaalenii_PYR-1 TELVARQLPEGLAAGSPQEREAVLGFLDEQVREH-QVVVPLAATFIRGVT Mb2960|M.bovis_AF2122/97 TGLSNRSVPDGVAAGSPEERAAVLGILAELLEDQTDPNAPLAAVHIAAAH Rv2935|M.tuberculosis_H37Rv TGLSNRSVPNGVAAGSPEERAAVLGILAELLEDQTDPNAPLAAVHIAAAH MLBr_02353|M.leprae_Br4923 TRLLTQTLPDGVAAGSAEERAVVSSILAELIASQSDLNEPLTAVQITTAH MMAR_1772|M.marinum_M TELATRQLPGDLAAGEADEHGAVSNIVAELIAEQGDSNAPLIAVHVTAPN MUL_2015|M.ulcerans_Agy99 TELATRQLPDDLAADEADEHSAVSNIVAELIAEQGDSNAPLIAVHVTAPN MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 LIAGFDELGAQLPGCIPFDRNTDPESFGQLLARAEDRGGPVTGIVWRATQ MSMEG_0408|M.smegmatis_MC2_155 LIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCAT TH_4621|M.thermoresistible__bu DVSATRLSDALKQAGAESTSMCWPQQADHADNVDRFRAGIADGVTGVVVL Mflv_3390|M.gilvum_PYR-GCK GG--------------PSYLALSLHGIAGDVSGDSASRDVLLTDLFTAFN Mvan_3123|M.vanbaalenii_PYR-1 GG--------------PSYLALSLHGIAG----DDVSRDVLLTDVFTAFS Mb2960|M.bovis_AF2122/97 GG--------------PHYLCLAIHAMVT----DDSSRQILATDIVTAFG Rv2935|M.tuberculosis_H37Rv GG--------------PHYLCLAIHAMVT----DDSSRQILATDIVTAFG MLBr_02353|M.leprae_Br4923 GG--------------PHYLGLAVHQMVI----DDASRQILGTDIITAFG MMAR_1772|M.marinum_M GG--------------AQYLGLALHEMVA----DDASRQLLGADIITAFA MUL_2015|M.ulcerans_Agy99 GG--------------AQYLGLALHETVA----DDASRQLLGADIITAFA MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 SGGRES--SAESVARLETEIAGLLTAVHALQNADGSAVKLPGGLWIVTER MSMEG_0408|M.smegmatis_MC2_155 PGRKESGSASAESARLEAEITNLLSAVHAAQ---GPSVKLPGGLWIVTEH TH_4621|M.thermoresistible__bu TGPKNGNPDDAAARRGSDYVRHLVRITRELAEIDGDAP----RLFVVTRG Mflv_3390|M.gilvum_PYR-GCK QRMAGEEIVLAPVTASWREWSQRCAGLAGHPAVLDSRDYWLQTAHRSTLR Mvan_3123|M.vanbaalenii_PYR-1 QRMAGEEIVLAPVPASWREWSQRCAGLASHPAVLDSRDYWLQTAGASTLR Mb2960|M.bovis_AF2122/97 QRLAGEEITLEPVSTGWREWSLRCAALATHPAALDTRSYWIENSTKATLW Rv2935|M.tuberculosis_H37Rv QRLAGEEITLEPVSTGWREWSLRCAALATHPAALDTRSYWIENSTKATLW MLBr_02353|M.leprae_Br4923 QRLAGEEITLEPVTTGWREWSLRCAALATHPAALDTRSFWIENANKVNLW MMAR_1772|M.marinum_M QRLGDQEIKLDPVTTGWRDWSVRCAALATHPAALDTRSYWIEQSTKANLW MUL_2015|M.ulcerans_Agy99 QRLDDQEIKLDPVTTGWRDWSVRCAALATHPAALDTRSYWIEQSTKANLW MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 GVATESGEPVDPVQAALWGLGRTIVNEEPALRCRLVDSDGSEQAVRSLAG MSMEG_0408|M.smegmatis_MC2_155 GVACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDLLAA TH_4621|M.thermoresistible__bu AQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIADDADLDRVAVQ Mflv_3390|M.gilvum_PYR-GCK VAGG----EPADRPG--AADLERLSTMLSAAETGEFDDARRRLRLSAEEI Mvan_3123|M.vanbaalenii_PYR-1 IAGP----EHSERPG--VDDVTRLSTALSAAETGEIDDARRRLRLPVEEI Mb2960|M.bovis_AF2122/97 LADALPNAHTAHPPR--ADELTKLSSTLSVEQTSELDDGRRRFRRSIQTI Rv2935|M.tuberculosis_H37Rv LADALPNAHTAHPPR--ADELTKLSSTLSVEQTSELDDGRRRFRRSIQTI MLBr_02353|M.leprae_Br4923 LADVSLNTDVIQPPG--ADDLIRMPCTLSVEQTSELDDARRRFRRSIQAI MMAR_1772|M.marinum_M LTDG----DAAQPPS--ATDLTKLPSVLNAEQTSELDDARRRFRRSIQTI MUL_2015|M.ulcerans_Agy99 LTDG----DAAQPPS--ATDLTKLPSVLNAEQTSELDDARRRFRRSIQTI MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 LLGAP-LDEPELAVR---QGKLLASRLLPWARSGHLAVPRGTDYVLAPTE MSMEG_0408|M.smegmatis_MC2_155 LLAAPGIQEPEIAVR---QGKLLASRLLPWARSGHLTLPRGGDFVLAPTE TH_4621|M.thermoresistible__bu LLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQAVVDCERDGMRLEIRT Mflv_3390|M.gilvum_PYR-GCK LLAALGRAVAVTVGEGAVAVDLGGRGRSVLKPDVDLARTVGSFAALHPVV Mvan_3123|M.vanbaalenii_PYR-1 LLAALGRAVAATVGEGAVSVDLGGRGRSVLKPDVDLQRTVGWFTTIHPVV Mb2960|M.bovis_AF2122/97 LLAALGRTIAQTVGEGVVAVELEGEGRSVLRPDVDLRRTVGWFTTYYPVP Rv2935|M.tuberculosis_H37Rv LLAALGRTIAQTVGEGVVAVELEGEGRSVLRPDVDLRRTVGWFTTYYPVP MLBr_02353|M.leprae_Br4923 VLAALGRTIAQTVGDGVVAVELEGEGRSVLRPDVDVRRTIGWFTNYYPIP MMAR_1772|M.marinum_M LLAALGRTIAQTVGDGVVAVELDGEGRSVLRPDVDVRRTVGRFTTYYPVA MUL_2015|M.ulcerans_Agy99 LLAALGRTIAQTVGDGVVAVELDGEGRSVLRPDVDVRRTVGRFTTYYPVA MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 RGAIDNLRLIEQEAPPPAEGCVQVRVEAGGLNFREVLNVLGLYPGDPG-- MSMEG_0408|M.smegmatis_MC2_155 RGAIDNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPG-- TH_4621|M.thermoresistible__bu PGDLETMELAAFDRVPPGPGQIEVAVTASSINFADVLIAFGRYPTFDGRR Mflv_3390|M.gilvum_PYR-GCK LT-ASGQ--TASAALAEVRQTLDAVPHYGIGYGLLRYLYAPTARLLGDGR Mvan_3123|M.vanbaalenii_PYR-1 LT-AARQG-SATQALGDVRETLKAVPHYGIGYGLLRYLYAPTARVLGASR Mb2960|M.bovis_AF2122/97 LACATGLG--ALAQLDAVHNTLKSVPHYGIGYGLLRYVYAPTGRVLGAQR Rv2935|M.tuberculosis_H37Rv LACATGLG--ALAQLDAVHNTLKSVPHYGIGYGLLRYVYAPTGRVLGAQR MLBr_02353|M.leprae_Br4923 LVCVKGQG--ALAQLDAVHNTLKSIPHYGIGYGLLRYMYAPTGRVFSAQR MMAR_1772|M.marinum_M LTCATGQGAAALKGLDAVHDTLKSVPHYGIGYGLLRYLYAPTGRVLGAQR MUL_2015|M.ulcerans_Agy99 LTCATGQGAAALKGLDAVHDTLKSVPHYGIGYGLLRYLYAPTGRVLGAQR MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 -PLGGDFAGTVTQLGSGVTGLEVGTRVYGFMQG-AFASRFNVPVQLLAPI MSMEG_0408|M.smegmatis_MC2_155 -PIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQG-AFASRFNVPAQFLAPI TH_4621|M.thermoresistible__bu PQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGCWSTFVTCDADLAVPL Mflv_3390|M.gilvum_PYR-GCK PADILFSHVGTIPDAPADQPD--DAPVRFDPDTAMPIRDALPGLGHALEV Mvan_3123|M.vanbaalenii_PYR-1 PADILFSHIGTIPEVPAEQPD--DAPVRFDADTAMPIRDALPGLGHAVEL Mb2960|M.bovis_AF2122/97 TPDIHFRYAGVIPELPSG-----DAPVQFDSDMTLPVREPIPGMGHAIEL Rv2935|M.tuberculosis_H37Rv TPDIHFRYAGVIPELPSG-----DAPVQFDSDMTLPVREPIPGMGHAIEL MLBr_02353|M.leprae_Br4923 TPDIHFRYVGVVPEPPSV-----DATVQFDSDMTIPVQEPVPGMGHAIEL MMAR_1772|M.marinum_M TPDIHFRYAGTIPELPPV-----DAPVQFDSDLAMPVREPLPGLGHAVEI MUL_2015|M.ulcerans_Agy99 TPDIHFRYAGTIPELPPV-----DAPVQFDSDLAMPVREPLPGLGHAVEI MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 PDGVSAVDAATIPAAALTARL-AFDWAQLKPGDRVLIHAASGGVGLAAIQ MSMEG_0408|M.smegmatis_MC2_155 PDGIGAVEAATIPAAALTVRL-AFDWAQLKPGDKVLIHAASGGVGLAAIQ TH_4621|M.thermoresistible__bu PDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLIHSATGGVGLAAIA Mflv_3390|M.gilvum_PYR-GCK RIYRTGGELHLDWWY--DIRRLGPTDVESFSRQYSAAVLDISREALAEED Mvan_3123|M.vanbaalenii_PYR-1 RVYRAAGVLHLDWWY--DNRRLGPTDVESFARQYSEALLDVTRDALAEED Mb2960|M.bovis_AF2122/97 RVYRFGGSLHLDWWY--DTRRIPAATAEALERTFPLALSALIQEAIAAEH Rv2935|M.tuberculosis_H37Rv RVYRFGGSLHLDWWY--DTRRIPAATAEALERTFPLALSALIQEAIAAEH MLBr_02353|M.leprae_Br4923 RTYRFGGSLHLDWWY--DIRRIPQVTAEALAQSFPVTLSKLIQEGIATQK MMAR_1772|M.marinum_M RAYRSGSSLHVDWWY--DTRRITAETATALARSFPTALSELIQESIAAEQ MUL_2015|M.ulcerans_Agy99 RAYRSGSSLHVDWWY--DTRRITAETATALARSFPTALSELIQESIAAEQ MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 LAQRHGATVFATAST-YKRATLRKLGVEYVYDSRSTDFADQILADTDGAG MSMEG_0408|M.smegmatis_MC2_155 MAQQSGAEVFATAST-FKRSTLRRLGVKYVYDSRTTDFADQILADTNGAG TH_4621|M.thermoresistible__bu IARSVGAQIYATAGSPARRDLLRDMGIEHVYDSRSTAFADEIRRDTDGYG Mflv_3390|M.gilvum_PYR-GCK TDAAGDELA-------LVDLS----------------------------- Mvan_3123|M.vanbaalenii_PYR-1 TDAAGDELA-------LVDLS----------------------------- Mb2960|M.bovis_AF2122/97 TEHDDSEIVGEPEAGALVDLSSMDAG------------------------ Rv2935|M.tuberculosis_H37Rv TEHDDSEIVGEPEAGALVDLSSMDAG------------------------ MLBr_02353|M.leprae_Br4923 DAHDESEMAGAPQAGVLVDLSTLDAG------------------------ MMAR_1772|M.marinum_M EERDEDEKVGVIEAGALVDLSSLDAG------------------------ MUL_2015|M.ulcerans_Agy99 EERDEDEKVGVIEAGALVDLPSLDAG------------------------ MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 VDVVLNSLTNEGFIEATVRATAQHGRFVEIAKRDIW--TREQMAAARPDI MSMEG_0408|M.smegmatis_MC2_155 VDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIW--SHEQMAEARPDI TH_4621|M.thermoresistible__bu VDVVLNSLP-GAAQRAGLELLSFGGRFIEIGKRDIYGDTRLGLFPFRRNL Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 AYEIVALDWACVEQPEHIHALLTEVSDGLASGEWRPLPAEIYPLAEAKTA MSMEG_0408|M.smegmatis_MC2_155 AYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSA TH_4621|M.thermoresistible__bu AFHGVDLGLMADSHPHKIRELLETVYRLTADGVLPMPQSTHYPLAEAATA Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 FRRMQQARHIGKIVLQMPKP------------LQPRGDRSYLITGGLGAI MSMEG_0408|M.smegmatis_MC2_155 FRRMQQARHIGKIVLQVPKP------------LQPQQDRSYLITGGLGAI TH_4621|M.thermoresistible__bu IRVMSAAEHVGKLVLDVPHTGRADVVVPPEQASPFRSDGAYIVTGGMGGL Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 GLHLAAYLAQLGAGEIVLTSRRAPDAAAWRAIDDITERYRCRVHTFAADV MSMEG_0408|M.smegmatis_MC2_155 GLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV TH_4621|M.thermoresistible__bu GLYLAGEMAAAGAGCIVLNGRSAPSGEALRTIEQLRAAGTEVIVECGXXX Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 GDAAQVEQLLARIRAELPPLAGVAHLAGVLDDALLSQQSPERFRVALAPK MSMEG_0408|M.smegmatis_MC2_155 GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPK TH_4621|M.thermoresistible__bu --------------------RGQPVEVAVPTELRHADEHPDRRGAQLCDE Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 AFG-ASYLDHATRTDDLDFFIVSSSVSSLLGSPGQANYSTANAWLDGLVA MSMEG_0408|M.smegmatis_MC2_155 AYG-ASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANYATANAMLDGLVA TH_4621|M.thermoresistible__bu FARGEQGAQRNQHRTDAGEGQRDAHPPGAVGHDQPDPGALSDTGLDERGG Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 ARQARGLPATGVNLGPWAQGGMASSEAARANIGAQGLIPLEPTAALAALA MSMEG_0408|M.smegmatis_MC2_155 KRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDPSAALHALA TH_4621|M.thermoresistible__bu QFPGVGVQIPVADPG----VGIDHRGAVRVDSGVPAQQGVDGEVVRHRTL Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 EVVANGTGQATVIKANWQRAAKLLGGARPPILDLVLPSAVGEASGDSELL MSMEG_0408|M.smegmatis_MC2_155 EVIANGSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELL TH_4621|M.thermoresistible__bu SSVRSGRSSRWTAPGSRCGSGRRYGGESCRRTTGPAAGAAARRGRTRRRR Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 KQLQEIPVAQRAAFITEFLQREVQGFLRLAQPPAATSRFLDLGTDSLMAV MSMEG_0408|M.smegmatis_MC2_155 KQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTDSLMAI TH_4621|M.thermoresistible__bu RPRRPPPPPDRVRHRAGPAHGPVRR------------------------- Mflv_3390|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3123|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb2960|M.bovis_AF2122/97 -------------------------------------------------- Rv2935|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02353|M.leprae_Br4923 -------------------------------------------------- MMAR_1772|M.marinum_M -------------------------------------------------- MUL_2015|M.ulcerans_Agy99 -------------------------------------------------- MAB_2256|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_1763|M.avium_104 ELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYLAGQLPDAESEPGAAVA MSMEG_0408|M.smegmatis_MC2_155 ELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEAPETA--- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_3390|M.gilvum_PYR-GCK ------------------------- Mvan_3123|M.vanbaalenii_PYR-1 ------------------------- Mb2960|M.bovis_AF2122/97 ------------------------- Rv2935|M.tuberculosis_H37Rv ------------------------- MLBr_02353|M.leprae_Br4923 ------------------------- MMAR_1772|M.marinum_M ------------------------- MUL_2015|M.ulcerans_Agy99 ------------------------- MAB_2256|M.abscessus_ATCC_1997 ------------------------- MAV_1763|M.avium_104 ANPNPGSETGTGEAEPEREAAPEPS MSMEG_0408|M.smegmatis_MC2_155 ------------------------- TH_4621|M.thermoresistible__bu -------------------------