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M. leprae Br4923 MLBr_02353 (-)

annotation: polyketide synthase
coordinates: 2794826 - 2799295
length: 1489

ITPDNAIAVVGMAGKFPGANDVSAFWTNLRRGKESIVTLSEQELRDNGVSDKALADPAYVRRAPLLDGID
EFDADFFGLPPLAAQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVYGTSSPSGYLLHNLLSHRDPHT
VLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGPSIAVQTACSSSLVALHLACLSLLSGECDMALAGGS
SLCIPHRVGYWHSPGSMVSAVGHCRPFDVRADGTVFGSGVALVALKPLQAAIDASDRIHAVILGSAINND
GSMKMGYAAPNPAAQADVIAEAHAVAGIDSSTVSYVETHGTGTPLGDPIEIQGLKTAFEVSQIPRPGPCV
LGSVKSNIGHLEVAAGIAGLIKTILCLKNKAIPATLHYTSPNRELRLDQTPFVVQSNYGPWKWDGVRRAG
VSSFGVGGTNVHVVLEEASVEASTVAASTGPQVILLSAQTAAALGESREALATVLEKPGAPDLSDVAYTL
AGRRKHNITMAAVVRDREHAVTVLRAAEHDNVFVGESGADTGRSAAASITTLGSDRVVFLFPGQGAQHVG
MAKGLYDTESVFAEHFDTCSAGFREAMDDLDLHSAIFNGTAIDLERIDRSQPALFTVEYALAKLVESFGV
GAGAYIGYSTGEYIAATLAGVFDLETAIKTVSLRARLMHESPPGAMVAVALGPEDITEYLAEYSAKGVEL
SAVNDPGNCVVAGPKDQIRAFSQRLDEVGIPVRRVRATHAFHTSSMEPMLREFSEFLSRQQLRVPNTPLL
SNLTGTWMSEQQVTDPENWTRQISSTIRFADELDVVLSQSGRVLVEVGPGGSLTGSAMRHPRWSSGHRAV
RLMRHPLQNVDDHDTFLRALGELWSAGIEVDWAPQRSVMPHLVSLPGYPFARQRHWVEPRYTIWAQIPGA
SSGSPVDSSVDSATVEGVRGGESQTEATLQRIWSQCLGVSSVDRNANFFDLGGDSLMAISISMAAANEGM
TITPQDMYEHPTLASLTAAVDASFASSGLAKPPEAAAHPAVPPNIAYFLERGLCDTGRWRVPLILRLDPK
IGSDDIRAVLTAVVNHHDVLRLSLVDNDGMWEQHIAATGEFTRLLTQTLPDGVAAGSAEERAVVSSILAE
LIASQSDLNEPLTAVQITTAHGGPHYLGLAVHQMVIDDASRQILGTDIITAFGQRLAGEEITLEPVTTGW
REWSLRCAALATHPAALDTRSFWIENANKVNLWLADVSLNTDVIQPPGADDLIRMPCTLSVEQTSELDDA
RRRFRRSIQAIVLAALGRTIAQTVGDGVVAVELEGEGRSVLRPDVDVRRTIGWFTNYYPIPLVCVKGQGA
LAQLDAVHNTLKSIPHYGIGYGLLRYMYAPTGRVFSAQRTPDIHFRYVGVVPEPPSVDATVQFDSDMTIP
VQEPVPGMGHAIELRTYRFGGSLHLDWWYDIRRIPQVTAEALAQSFPVTLSKLIQEGIATQKDAHDESEM
AGAPQAGVLVDLSTLDAG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02353--100% (1489)polyketide synthase
M. leprae Br4923MLBr_00135-e-12334.91% (928) putative polyketide synthase
M. leprae Br4923MLBr_02354-e-12035.08% (915) polyketide synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2960ppsE0.082.02% (1496) phenolpthiocerol synthesis type-I polyketide synthase PPSE
M. gilvum PYR-GCKMflv_3390-0.055.94% (1498) beta-ketoacyl synthase
M. tuberculosis H37RvRv2935ppsE0.081.95% (1496) phenolpthiocerol synthesis type-I polyketide synthase PPSE
M. abscessus ATCC 19977MAB_2256-0.039.33% (1012) polyketide synthase
M. marinum MMMAR_1772ppsE0.078.63% (1493) phenolpthiocerol synthesis type-I polyketide synthase PpsE
M. avium 104MAV_1763-1e-13634.60% (951) tylactone synthase modules 4 & 5
M. smegmatis MC2 155MSMEG_0408-1e-13935.38% (944) type I modular polyketide synthase
M. thermoresistible (build 8)TH_4621-1e-11834.71% (896) PUTATIVE mycocerosic acid synthase
M. ulcerans Agy99MUL_2015ppsE0.078.23% (1493) phenolpthiocerol synthesis type-I polyketide synthase PpsE
M. vanbaalenii PYR-1Mvan_3123-0.056.73% (1486) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                MSTVEGLRDPASSFAIVGYAARFPGAADADEFWRVLAEGRDAVSEVPKDR
MSMEG_0408|M.smegmatis_MC2_155      MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                WDADEFFDPDPDAPGKVVTRRAGFVDDVTGFDAPFFGMSAREARLLDPQH
MSMEG_0408|M.smegmatis_MC2_155      WDIEEFFDPDPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQH
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                RLLLETAWRAVEHSGTAPTDLANTNTGVFIGISTHDYLGMASDELTYDQI
MSMEG_0408|M.smegmatis_MC2_155      RILMETAWRAVEHSGIAPTSLANSNTGVFVGLATHDYLGMASDELTYPEI
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                EAYTAIGTSSAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
MSMEG_0408|M.smegmatis_MC2_155      EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                GECDLALAGGANVLLTPATMITFSQAHMLAPDGRCKTFDAAADGYVRGEG
MSMEG_0408|M.smegmatis_MC2_155      NECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                CGVLVVKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
MSMEG_0408|M.smegmatis_MC2_155      CGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                EALQRAGIAPGDVDYLEAHGTGTSLGDPIEVQAAGAVLGAGREASRPLLI
MSMEG_0408|M.smegmatis_MC2_155      DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLI
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                GSVKTNIGHLEAAAGIAGVIKVILALEHGMLPQHLHFRDPSPHIPWDRLA
MSMEG_0408|M.smegmatis_MC2_155      GSAKTNIGHLEAAAGIAGVIKVVMALENETLPKHLNFETPSPHIPWERLP
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                VQVVKEATAWQRNGRPRVAGVSSFGFAGTNAHVILEEAPDGTGRAAVPPA
MSMEG_0408|M.smegmatis_MC2_155      IEVVRETVPWQRNGKPRIAGVSSFGFAGTNAHVILEEAP-AVGTPATTEP
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                AVRPPGQRRFHVLPLSARTPAALVQIAGEYRDWLSAHPDTALADLCLTAG
MSMEG_0408|M.smegmatis_MC2_155      VEDP---RRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVSHTAG
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                AGRAHFEHRAALVVDSTGSAGELLAALADDRPAPGLLRGVCEDAPKTAWL
MSMEG_0408|M.smegmatis_MC2_155      TARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWL
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                FTGQGSQYAGMARELFDTEPVFAETLTRCATVLADVLEKPLLDVIFDTDD
MSMEG_0408|M.smegmatis_MC2_155      FTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADE
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                P--ASEATLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSA
MSMEG_0408|M.smegmatis_MC2_155      LDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSA
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                ACVAGVLRVEDGARLIAERGRLFGSLPAGGRMVAAFAAAARVEGLTDEFP
MSMEG_0408|M.smegmatis_MC2_155      ACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYP
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                SLSVAAYNGANTVLSGPGQELEQAVARLTAEKVRCDWLDTSHAFHSALLD
MSMEG_0408|M.smegmatis_MC2_155      SLSVAAYNGANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLD
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                PILDEFESYANQFDFGPPQRILICNRTGSALGRSVKLDGAYWRRHARQPV
MSMEG_0408|M.smegmatis_MC2_155      PILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQPV
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                EFAKSVHTLADLGCKVLLEIGPQPVLTAAALRAWPDPATAPRAIASLRRN
MSMEG_0408|M.smegmatis_MC2_155      EFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRPT
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                TADHRQITEALAEAYIVGHLPDFGAAVGP-ARKLDLPTYPFQHRQYWFSE
MSMEG_0408|M.smegmatis_MC2_155      TADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSD
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                QRVPPGSQQTS-------TQTTAVRLLEDGRIAELAELLDGASADQHTLD
MSMEG_0408|M.smegmatis_MC2_155      NRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                VLTKLAAQHNQQRKSRSIAEDRYEIRWEKSTVPGP--EAEATWLVVGDDD
MSMEG_0408|M.smegmatis_MC2_155      VLNKLAARHNQQRSTHVDPDARYEIRWDAIASAAASTGAAADWILVGDDT
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                DAVAPLVDALTARGHQHRILVLPASDADEERLEIVLRAAAAEEAPLRIAL
MSMEG_0408|M.smegmatis_MC2_155      AAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAGE--LYVVH
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                VAALDSGTAPSMRSLLRMQHRVLAGTRRLFRAAAAAELRQPIWLVTRGAQ
MSMEG_0408|M.smegmatis_MC2_155      IAAGDGAAAP-MRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQ
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                RVTDADTVFPDQSCLWGFGRAASLEYPQLWGGLADLAQGSAEEWSRLVRV
MSMEG_0408|M.smegmatis_MC2_155      RVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLS-GADTEWPRLIAR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                ASAPRDPAVGEDQIALRGSDIYVPRLTRRSGQPAAAALTLRADATYLVTG
MSMEG_0408|M.smegmatis_MC2_155      ITSPRD---GEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTG
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                GLGSIGLEIAGHLAAQGARHLVLTGRRAPGEAAQRRIDALSQQHGCEVRV
MSMEG_0408|M.smegmatis_MC2_155      GLGAIGLEVAGYLASHGAGHVVLTSRREPGDDARRRLDGLREQYACDVRV
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      ----------------------------------------------MQHS
MAV_1763|M.avium_104                IAADVADAHHVARLLGAVRAELPPVAGIVHAAGEIGTTPLSDLEDAEIDR
MSMEG_0408|M.smegmatis_MC2_155      ITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDR
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      STAAELQRKWLRGGAFEPDRHPALVVFPHAGGGATFYRSWLTNPDFSVHV
MAV_1763|M.avium_104                VFAGKVWGAWHLSEAAADLR--LDFFVSTSSIASVWGGLGQTAYGAANAF
MSMEG_0408|M.smegmatis_MC2_155      VFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAF
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      VQYPGREDRISEQLPSSLGALADGVAEALLTVGDRPLYLFGHSMGALVAF
MAV_1763|M.avium_104                LDGLAWRLREQGVNGISVNFGPWAAGMADENARARLAQRGIKTLSPADAL
MSMEG_0408|M.smegmatis_MC2_155      LDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQRGVRTLSPAEAL
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      EVARRLETADRFRQLRLCVSSYTAPHLVRSRGLRDMDDEAFVAYGRSATG
MAV_1763|M.avium_104                AGLADVMATAAAQGVVARIDWTRFLPLYQQAGQRSLLAELAREIPDFAP-
MSMEG_0408|M.smegmatis_MC2_155      AGMADVVAG-PVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATG
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      EVSAATGEASAFDVTALRDLVVAGLRADFHLVEQYRAEPKPPVDAPILAL
MAV_1763|M.avium_104                ---APTPSGKTGLVERLAGAPVQQRRKLMTEFLRNAVAEVTRVDAAEIRE
MSMEG_0408|M.smegmatis_MC2_155      AAAPATVPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRD
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      WGDDEAI---------DPADMDLWADVTRGGYRSATFPGGHFYLAAERDA
MAV_1763|M.avium_104                DAGFFDLGMDSLMAIELRRHIEQGVGKQIPATLAMDYPRLSDVAEYLLGD
MSMEG_0408|M.smegmatis_MC2_155      EAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVE
TH_4621|M.thermoresistible__bu      ------------------------------VNIVGDTP------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          -------MTSGTRDSTSDSPQDSLPDNAIAVIGMAGRFPGAQS-VSEFWR
Mvan_3123|M.vanbaalenii_PYR-1       -------MTSGASNNT-----DELPDNAIAVIGMAGRFPGAGS-VSEFWR
Mb2960|M.bovis_AF2122/97            ---------------------MSIPENAIAVVGMAGRFPGAKD-VSAFWS
Rv2935|M.tuberculosis_H37Rv         ---------------------MSIPENAIAVVGMAGRFPGAKD-VSAFWS
MLBr_02353|M.leprae_Br4923          ---------------------MITPDNAIAVVGMAGKFPGAND-VSAFWT
MMAR_1772|M.marinum_M               --------------------MSTIPDNAIAVVGMAGKFPGAKD-VSTFWS
MUL_2015|M.ulcerans_Agy99           --------------------MSTIPDNAIAVVGMAGKFPGAKD-VSTFWS
MAB_2256|M.abscessus_ATCC_1997      VLETVRQWWAELDGESEASEVHEVRDDDVAVIGIAARVPGAAS-LDEFWT
MAV_1763|M.avium_104                VLDLRGQPDAKPAPPAGTPAPAGRTDEPIAIVAMACRFPGAAD-PEAFWE
MSMEG_0408|M.smegmatis_MC2_155      VLGLGEQTNVRQAS-----TVTARTDDPIAVVAVSCRFPGAPD-PESFWE
TH_4621|M.thermoresistible__bu      -------------------------VNAVAVIGMACRLPGGIDSPQRLWE
                                                              : :*::.:: :.**. .  . :* 

Mflv_3390|M.gilvum_PYR-GCK          NLRGGVESIVDLSESELLAAGVTEQTLANR--SYVRRAALMSGIEEFDAD
Mvan_3123|M.vanbaalenii_PYR-1       NLRNGVESIVDLPEDELLANGVTERTLSNR--SYVRRAGLMPGIDEFDAD
Mb2960|M.bovis_AF2122/97            NLRRGKESIVTLSEQELRDAGVSDKTLADP--AYVRRAPLLDGIDEFDAG
Rv2935|M.tuberculosis_H37Rv         NLRRGKESIVTLSEQELRDAGVSDKTLADP--AYVRRAPLLDGIDEFDAG
MLBr_02353|M.leprae_Br4923          NLRRGKESIVTLSEQELRDNGVSDKALADP--AYVRRAPLLDGIDEFDAD
MMAR_1772|M.marinum_M               NLRRGKESIVTLSEEELREAGVSDKTLADP--SYVRRAPLVDGIDEFDAD
MUL_2015|M.ulcerans_Agy99           NLRRGKESIVTLSEEELREAGVSDKTLADP--SYVRRAPLVDGIDEFDAD
MAB_2256|M.abscessus_ATCC_1997      NLCAGEESLTRFTDEELLSAGVTPEELRDP--RLVRVRPILADVADFDTK
MAV_1763|M.avium_104                LLSGGVDAIREVPEDRFDIDEFYDPDPETPGKMYSRFGGYLDQIDEFDPE
MSMEG_0408|M.smegmatis_MC2_155      LLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRFGGFLDGIDGFDPE
TH_4621|M.thermoresistible__bu      ALLRGDDMVTEIPVDRWDADDYFDPEPGVPGRTVSRWGAFLDDVAGFDPE
                                     *  * : :  .. ..                   *    :  :  **. 

Mflv_3390|M.gilvum_PYR-GCK          FFGFTPQAAKALDPQHRLFLQTVFHAFEDAGYDPKGLEATVGVFGTSSTS
Mvan_3123|M.vanbaalenii_PYR-1       FFGFTPYAARMLDPQHRLFLQTVFHAMEDAGYDPKGLEATVGVFGTSSSS
Mb2960|M.bovis_AF2122/97            FFGFPPLAAQVLDPQHRLFLQCAWHALEDAGADPARFDGSIGVYGTSSPS
Rv2935|M.tuberculosis_H37Rv         FFGFPPLAAQVLDPQHRLFLQCAWHALEDAGADPARFDGSIGVYGTSSPS
MLBr_02353|M.leprae_Br4923          FFGLPPLAAQVLDPQHRLFLQCAWHALEDAGCDPAQFDGSIGVYGTSSPS
MMAR_1772|M.marinum_M               FFGFPPLAAQVLDPQHRLFLQCAWHALEDANCDPAKFDGSIGVYGTSSPS
MUL_2015|M.ulcerans_Agy99           FFGFPPLAAQVLDPQHRLFLQCAWHALEDANCDPAKFDGSIGVYGTSSPS
MAB_2256|M.abscessus_ATCC_1997      FFGYAPSEARSIDPQQRLFLECAWEAVESAGYDLQRYDGSVGVFGGSAGS
MAV_1763|M.avium_104                FFGISPREAVWIDPQQRLVLETVWEGLERAGYSPAALRGSR---------
MSMEG_0408|M.smegmatis_MC2_155      FFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSR---------
TH_4621|M.thermoresistible__bu      FFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSS---------
                                    *** .   *  ::**:**.*:  :...* *.       .:          

Mflv_3390|M.gilvum_PYR-GCK          GYLLHNLMSNYDPMMVIGQGASFDMVSLSLSNDKDHLATRVAHSYDLRGP
Mvan_3123|M.vanbaalenii_PYR-1       GYLLHNLMSNFDPMMVIGQGASFEMVNLSLQNDKDHLATRAAHQFDFRGP
Mb2960|M.bovis_AF2122/97            GYLLHNLLSHRDPNAVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGP
Rv2935|M.tuberculosis_H37Rv         GYLLHNLLSHRDPNAVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGP
MLBr_02353|M.leprae_Br4923          GYLLHNLLSHRDPHTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGP
MMAR_1772|M.marinum_M               GYLLHNLLSHRDPNTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGP
MUL_2015|M.ulcerans_Agy99           GYLLHNLLSHRDPNTVLAEGLNFDQFSLFLQNDKDFLATRISHAFNLRGP
MAB_2256|M.abscessus_ATCC_1997      TYYRAVLSTDYG------NLNGTEYLQTALATENDFLAPRVSYKLNLRGP
MAV_1763|M.avium_104                SGIFVGVGANEYSHLLSAESVDKIEPHFITGNALNAISGRVAFALGLEGP
MSMEG_0408|M.smegmatis_MC2_155      TGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGP
TH_4621|M.thermoresistible__bu      TGVFVGLSHDDYA-LLTSDAGALEEAYGFTGSAFSMASGRIAYRLGVHGP
                                          :  .        :            .  .  : * :.  ...**

Mflv_3390|M.gilvum_PYR-GCK          ALSVATACSSSLVAVHLACQSILNGECDIALAGGSSLRIPNRVGYWYAQG
Mvan_3123|M.vanbaalenii_PYR-1       ALSVATACSSSLVAVHLACQSLLNGECDIALAGGSSLRIPHHVGYWYEQG
Mb2960|M.bovis_AF2122/97            SIAVQTACSSSLVAVHLACLSLLSGECDMALAGGSSLCIPHRVGYFTSPG
Rv2935|M.tuberculosis_H37Rv         SIAVQTACSSSLVAVHLACLSLLSGECDMALAGGSSLCIPHRVGYFTSPG
MLBr_02353|M.leprae_Br4923          SIAVQTACSSSLVALHLACLSLLSGECDMALAGGSSLCIPHRVGYWHSPG
MMAR_1772|M.marinum_M               SIAVQTACSSSLVAVHLACLSLLSGECDVALAGGSSLCVPHHVGYFTSPG
MUL_2015|M.ulcerans_Agy99           SIAVQTACSSSLVAVHLACLSLLSGECDVALAGGSSLCVPHHVGYFTSPG
MAB_2256|M.abscessus_ATCC_1997      SISLGTGCSTSLVAIHLAVQSVLTGESDMALAGGASITFPQTAGYVATES
MAV_1763|M.avium_104                AVAVDTACSSSLVAVHQACQALHSGDCDLALAGGVNVLLSPVSNIAASRA
MSMEG_0408|M.smegmatis_MC2_155      AVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRA
TH_4621|M.thermoresistible__bu      AVTVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGL
                                    :::: *.**::*:*:* *  ::  *:.*:*****  : .           

Mflv_3390|M.gilvum_PYR-GCK          SMVTPTGQCRPFDVRADGTVFGSGVGVLVLKALEDAVADGDRIHAVIRGS
Mvan_3123|M.vanbaalenii_PYR-1       AMVSPTGQCRPFDVRSDGTIFASGVGVVVLKALADAIDDGDHIHAVIRGS
Mb2960|M.bovis_AF2122/97            SMVSAVGHCRPFDVRADGTVFGSGVGLVVLKPLAAAIDAGDRIHAVIRGS
Rv2935|M.tuberculosis_H37Rv         SMVSAVGHCRPFDVRADGTVFGSGVGLVVLKPLAAAIDAGDRIHAVIRGS
MLBr_02353|M.leprae_Br4923          SMVSAVGHCRPFDVRADGTVFGSGVALVALKPLQAAIDASDRIHAVILGS
MMAR_1772|M.marinum_M               SMVSAVGHCRPFDVRSDGTVFGSGVAMVVLKPLQAAIDAGDRIHAVIRGS
MUL_2015|M.ulcerans_Agy99           SMVSAVGHCRPFDVRSDGTVFGSGAAMVVLKPLQAAIDAGDRIHAVIRAS
MAB_2256|M.abscessus_ATCC_1997      GAISTSGRCRAFDASADGTLVGDGIGIVLLKRASNAVADGDSILGIIRGT
MAV_1763|M.avium_104                RMLSPVGRCKTFDATADGYVRSEGCGILVLKRMSDAVRDGDRVCAVIPAS
MSMEG_0408|M.smegmatis_MC2_155      RMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPAS
TH_4621|M.thermoresistible__bu      GMLSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGT
                                      ::. *:*:.**. :** : ..*  :: **    *:  .* : .:: .:

Mflv_3390|M.gilvum_PYR-GCK          ALNNDGATKMTYAAPNALGQAEVIAEAHAIAGVDASTITYVETHGTGTPL
Mvan_3123|M.vanbaalenii_PYR-1       ALNNDGSTKMTYAAPNALGQAEVIAEAHAIAGVDASSITYVETHGTGTPL
Mb2960|M.bovis_AF2122/97            AINNDGSAKMGYAAPNPAAQADVIAEAHAVSGIDSSTVSYVECHGTGTPL
Rv2935|M.tuberculosis_H37Rv         AINNDGSAKMGYAAPNPAAQADVIAEAHAVSGIDSSTVSYVECHGTGTPL
MLBr_02353|M.leprae_Br4923          AINNDGSMKMGYAAPNPAAQADVIAEAHAVAGIDSSTVSYVETHGTGTPL
MMAR_1772|M.marinum_M               AINNDGSAKMGYAAPNPAAQADVIAEAHAVSGIDASTVSYVECHGTGTPL
MUL_2015|M.ulcerans_Agy99           AINNDGSAKMGYAAPNPAAQADVIAEAHAVSGIDASTVSYVECHGTGTPL
MAB_2256|M.abscessus_ATCC_1997      AVNNDGGNKAGFAAPSISGQVEVITEALAVAEVPAQTVDYVETHGTGTPL
MAV_1763|M.avium_104                AVNQDGASSG-LTVPNGGAQQRLIATALSRAGLSGDDVDYLEAHGTGTAL
MSMEG_0408|M.smegmatis_MC2_155      SVNQDGASSG-LTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPL
TH_4621|M.thermoresistible__bu      AANQDGRTEN-ISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPV
                                    : *:**  .   :.*.  .*  :   : : : :    :  :* *****.:

Mflv_3390|M.gilvum_PYR-GCK          GDPIEVEGLRQAFELAEDERSAPCYLGSVKSNIGHLETAAGIAGLIKAIL
Mvan_3123|M.vanbaalenii_PYR-1       GDPIEIEGLRQAFELSEETRSAPCYLGSVKSNIGHLETAAGIAGLIKAIL
Mb2960|M.bovis_AF2122/97            GDPIEIQGLRAAFEVSQTSRSAPCVLGSVKSNIGHLEVAAGIAGLIKTIL
Rv2935|M.tuberculosis_H37Rv         GDPIEIQGLRAAFEVSQTSRSAPCVLGSVKSNIGHLEVAAGIAGLIKTIL
MLBr_02353|M.leprae_Br4923          GDPIEIQGLKTAFEVSQIPRPGPCVLGSVKSNIGHLEVAAGIAGLIKTIL
MMAR_1772|M.marinum_M               GDPIEIQGLRTAFEASETTRTGPCVLGSVKSNIGHLEVAAGIAGLIKTIL
MUL_2015|M.ulcerans_Agy99           GDPIEIQGLRTAFEASETTRTGPCVLGSVKSNIGHLEVAAGIAGLIKTIL
MAB_2256|M.abscessus_ATCC_1997      GDPIEIAALHKAFREAGDTRTQACRLGTLKPNIGHTGPASGVLALIKVLL
MAV_1763|M.avium_104                GDPIEVQAAGAVYGATRDT-DRPLLIGSVKTNIGHLEAASGVAGLIKVVL
MSMEG_0408|M.smegmatis_MC2_155      GDPIEVQAAAAAYGAGRDA-DRPLLMGSVKTNIGHTESASGAAGLIKVVL
TH_4621|M.thermoresistible__bu      GDPIEYNSLTQVYGKTG-----PCALTSVKTNFGHAESAAGALGMMKAIL
                                    *****  .   .:         .  : ::*.*:**   *:*  .::*.:*

Mflv_3390|M.gilvum_PYR-GCK          CLEHKAIPATLHYTSPNPELHLDRGPFRVRAQDGPWESDG--IRRAGVSS
Mvan_3123|M.vanbaalenii_PYR-1       CLEHKAIPATLHYTSPNPELHLDRGPFRIRSSDGPWESDG--IRRAGVSS
Mb2960|M.bovis_AF2122/97            CLKNKALPATLHYTSPNPELRLDQSPFVVQSKYGPWECDG--VRRAGVSS
Rv2935|M.tuberculosis_H37Rv         CLKNKALPATLHYTSPNPELRLDQSPFVVQSKYGPWECDG--VRRAGVSS
MLBr_02353|M.leprae_Br4923          CLKNKAIPATLHYTSPNRELRLDQTPFVVQSNYGPWKWDG--VRRAGVSS
MMAR_1772|M.marinum_M               CLKNRAIPATLHYTSPNPELRLEQSPFVVQNKYGPWEWDG--VLRAGVSS
MUL_2015|M.ulcerans_Agy99           CLKNRAIPATLHYTSPNPELRLEQSPFVVQNKYGPWEWDG--VLRAGVSS
MAB_2256|M.abscessus_ATCC_1997      AFQHRMYPPAANFTAPNPQIEFSKSPFYVGTRLRRWNAPGGKPRRAGVSS
MAV_1763|M.avium_104                SLQHEMLPQSLHFETPSPHIPWDSLPLRVVDKAVPWQT-NGRPRRAGVSS
MSMEG_0408|M.smegmatis_MC2_155      SLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQT-NGRVRRAGVSS
TH_4621|M.thermoresistible__bu      ALQHGVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVREGCPRRAAVSS
                                    .:::   *   ::     .:      . :      *        **.***

Mflv_3390|M.gilvum_PYR-GCK          FGVGGTNAHIILEEAP-VAPARAQTS----------SPARPSVLVLSART
Mvan_3123|M.vanbaalenii_PYR-1       FGVGGTNAHIVLEEAP-TAPVPAPRS----------G---PQVLVLSART
Mb2960|M.bovis_AF2122/97            FGVGGTNAHVVLEEAPAEASEVSAHA----------EPAGPQVILLSAQT
Rv2935|M.tuberculosis_H37Rv         FGVGGTNAHVVLEEAPAEASEVSAHA----------EPAGPQVILLSAQT
MLBr_02353|M.leprae_Br4923          FGVGGTNVHVVLEEASVEASTVAAS-------------TGPQVILLSAQT
MMAR_1772|M.marinum_M               FGVGGTNAHVVLEEAP----TVPAHD----------EPAGPQVLLLSAQT
MUL_2015|M.ulcerans_Agy99           FGVGGTNAHVVLEEAP----TVPAHD----------EPAGPQVLLLSAQT
MAB_2256|M.abscessus_ATCC_1997      YSMGGTNAHAVLQEPP---RAELPPK----------SQEGAHLLVLSART
MAV_1763|M.avium_104                FGFTGTNAHVLIEEAPQPVTTQDAT---PAAESDARPVD---VLPLSARS
MSMEG_0408|M.smegmatis_MC2_155      FGFTGTNAHVLVEEAPPQLHTADAAPVEPAATAEAGTDDSPQVLALSARS
TH_4621|M.thermoresistible__bu      YGMSGTNVHAVLEQAPEPVQRPEES--------ADTDAAGPLVFALSSTS
                                    :.. ***.* ::::..                          :: **: :

Mflv_3390|M.gilvum_PYR-GCK          QEALEDSRATLARELGENA-EISLPDVAYTLGR-RRKEPIRLAAVVRDQA
Mvan_3123|M.vanbaalenii_PYR-1       EETLAQSRAALAAELSEVD-EISLPDAAYTLTH-RRKDPVRLAAVVHDQE
Mb2960|M.bovis_AF2122/97            AAALGESRTALAAALETQD-GPRLSDVAYTLAR-RRKHNVTMAAVVHDRE
Rv2935|M.tuberculosis_H37Rv         AAALGESRTALAAALETQD-GPRLSDVAYTLAR-RRKHNVTMAAVVHDRE
MLBr_02353|M.leprae_Br4923          AAALGESREALATVLEKPG-APDLSDVAYTLAG-RRKHNITMAAVVRDRE
MMAR_1772|M.marinum_M               AAALTESRTALAEVLERSD-SPDLSDVAYTLSR-RRKHNVTMAAVVSDRE
MUL_2015|M.ulcerans_Agy99           AAALTESRTALAEVLGRSD-SPDLSDVAYTLSR-RRKHNVTMAAVVSDRE
MAB_2256|M.abscessus_ATCC_1997      APALEAARKNLAHHLARHP-EQDLAAVAATLRLGRRAFSHRFAAVCADRP
MAV_1763|M.avium_104                PEALLALAQRYGEWLHAHP-DADIGDLCFTVGAGRAHFEHRAALVVDSVR
MSMEG_0408|M.smegmatis_MC2_155      PEALVELARRYDDWLSATP-GLDIADVCHTAGVGRSHFEYRAALVVDSVE
TH_4621|M.thermoresistible__bu      AEELRRTAGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVRTTVIADGVE
                                       *          :            . *    *       : :  .  

Mflv_3390|M.gilvum_PYR-GCK          NAATVLSAAETDGATDNVFIGR--------GHPDWDSSATDRIAFLFPGQ
Mvan_3123|M.vanbaalenii_PYR-1       NAATVLSAAETD----NVFIGR--------AVPDLQDSA-ERVAFLFPGQ
Mb2960|M.bovis_AF2122/97            HAATVLRAAEHD----NVFVGEAAHDGEHGDRADAAPT-SDRVVFLFPGQ
Rv2935|M.tuberculosis_H37Rv         HAATVLRAAEHD----NVFVGEAAHDGEHGDRADAAPT-SDRVVFLFPGQ
MLBr_02353|M.leprae_Br4923          HAVTVLRAAEHD----NVFVGESGADTGRSAAASITTLGSDRVVFLFPGQ
MMAR_1772|M.marinum_M               EAATALRAADND----SIFVGESVAG-----VADATAAAAERVVFLFPGQ
MUL_2015|M.ulcerans_Agy99           EAATALRAADND----SIFVGESVAG-----VADATAAAAERVVFLFPGQ
MAB_2256|M.abscessus_ATCC_1997      EALQVLEGTGHAP-----------------FRTGTAADKPRPVVFLFPGQ
MAV_1763|M.avium_104                SAREALADLADN--------------RTRPGVARGECTDPPTTAWLFTGQ
MSMEG_0408|M.smegmatis_MC2_155      RAREGLAALAEG--------------RTPAGVVRGEHVHRPTTAWLFTGQ
TH_4621|M.thermoresistible__bu      ALTAGLREVADG--------------DAPYQPAVGMDDKAP--VWVFSGQ
                                         *                                     .::*.**

Mflv_3390|M.gilvum_PYR-GCK          GAQHIGMARGLHDNEPVFARYFDECATAFSDEMG-FDLRAEIFDG-----
Mvan_3123|M.vanbaalenii_PYR-1       GAQHVGMARGLYDNEPVFKRHFDECATAFSDDMG-YDLRAEIFDG-----
Mb2960|M.bovis_AF2122/97            GAQHVGMAKGLYDTEPVFAQHFDTCAAGFRDETG-IDLHAEVFDG-----
Rv2935|M.tuberculosis_H37Rv         GAQHVGMAKGLYDTEPVFAQHFDTCAAGFRDETG-IDLHAEVFDG-----
MLBr_02353|M.leprae_Br4923          GAQHVGMAKGLYDTESVFAEHFDTCSAGFREAMDDLDLHSAIFNG-----
MMAR_1772|M.marinum_M               GAQHVGMAKGLYETEPVFAEHFDACAAGFRAEMG-VDLNAEIFNG-----
MUL_2015|M.ulcerans_Agy99           GAQHVGMAKGLYETEPVFAEHFDACAAGFRAEMG-VDLNAEIFNG-----
MAB_2256|M.abscessus_ATCC_1997      GSQFSGMGEQLYTTSSMYRRHIDECATLFEPLIG-VDLRTMLCAEGDEA-
MAV_1763|M.avium_104                GSQYPGMARELFDAEPVFAETVTRCADAVDGLLPRPLTEVIFATDKDTGG
MSMEG_0408|M.smegmatis_MC2_155      GSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET--
TH_4621|M.thermoresistible__bu      GSQWAGMGAELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTG-
                                    *:*  **.  *   . ::   .      .                     

Mflv_3390|M.gilvum_PYR-GCK          -VGRNLEHTDRAQPALFTVEYALARLIQSYGVEPAIMAGHSIGEYPAATL
Mvan_3123|M.vanbaalenii_PYR-1       -VGRNLEHTDRAQPALFTVEYALAKLVQSYGVEPAIMAGHSIGEYPAATI
Mb2960|M.bovis_AF2122/97            -TATDLERIDRSQPALFTVEYALAKLVDTFGVRAGAYIGYSTGEYIAATL
Rv2935|M.tuberculosis_H37Rv         -TATDLERIDRSQPALFTVEYALAKLVDTFGVRAGAYIGYSTGEYIAATL
MLBr_02353|M.leprae_Br4923          -TAIDLERIDRSQPALFTVEYALAKLVESFGVGAGAYIGYSTGEYIAATL
MMAR_1772|M.marinum_M               -TATDLERIDRSQPALFTVEYALAKLVDTYGVRAGAYIGYSTGEYIAATL
MUL_2015|M.ulcerans_Agy99           -TGTDLERIDRSQPALFTVEYALAKLVDTYGVRAGAYIGYSTGEYIAATL
MAB_2256|M.abscessus_ATCC_1997      -TDAALMQTRLTQPALFTVGYALSQLLGAWGVQPVAMLGHSIGELVAACA
MAV_1763|M.avium_104                EAGKTLRNTAFAQPALFAVEMGLARLWQSWGVEPDVVLGHSVGQYAAACV
MSMEG_0408|M.smegmatis_MC2_155      --ADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACV
TH_4621|M.thermoresistible__bu      --------IDRVQPTLFAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVV
                                                **:**::  .*:    ::.: .    *:* *:  **  

Mflv_3390|M.gilvum_PYR-GCK          AGVFDLDTAVKVVATRAKLMHAAP-RGVMIAVPLSPDAVAEYLTP----D
Mvan_3123|M.vanbaalenii_PYR-1       AGVFDLDTAVKVVSKRAKLMHAAP-RGVMVAVPLSPEAVAEHLTP----D
Mb2960|M.bovis_AF2122/97            AGVFDLQTAIKTVSLRARLMHESP-PGAMVAVALGPDDVTQYLPP----E
Rv2935|M.tuberculosis_H37Rv         AGVFDLQTAIKTVSLRARLMHESP-PGAMVAVALGPDDVTQYLPP----E
MLBr_02353|M.leprae_Br4923          AGVFDLETAIKTVSLRARLMHESP-PGAMVAVALGPEDITEYLAEYSAKG
MMAR_1772|M.marinum_M               AGVFDLETAIKTVSLRARLMHESP-PGAMVAVAVGPDEIAQYLGD----G
MUL_2015|M.ulcerans_Agy99           AGVFDLETAIKTVSLRARLMHESP-PGAMVAVAVGPDDFAQYLGD----G
MAB_2256|M.abscessus_ATCC_1997      AGVFTIEEAVQLAARRGDLIQQCP-SGAMAAVGGSLEVVSALLPEG----
MAV_1763|M.avium_104                AGVFSLEDGARLMAERGRLFGGLPDGGRMVAVFADAQYVEELANDCPRVS
MSMEG_0408|M.smegmatis_MC2_155      AGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVS
TH_4621|M.thermoresistible__bu      AGALSLEDGVKVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDD
                                    **.: :: . :  . *. :    .  * * *:    : .           

Mflv_3390|M.gilvum_PYR-GCK          VDIATINDPGSCVVAGTDEAIRAFQAGLAEKGVAARRVRTAHAFHSRLMD
Mvan_3123|M.vanbaalenii_PYR-1       VDVATINDPGSCVVAGSEEAIRTFQAALAEKGVAARRVRTSHAFHSRLMD
Mb2960|M.bovis_AF2122/97            VELSAVNDPGNCVVAGPKDQIRALRQRLTEAGIPVRRVRATHAFHTSAMD
Rv2935|M.tuberculosis_H37Rv         VELSAVNDPGNCVVAGPKDQIRALRQRLTEAGIPVRRVRATHAFHTSAMD
MLBr_02353|M.leprae_Br4923          VELSAVNDPGNCVVAGPKDQIRAFSQRLDEVGIPVRRVRATHAFHTSSME
MMAR_1772|M.marinum_M               VELSAVNDPGNCVVAGPKDEIRAFSQRLNEAGIPVRRVRATHAFHSSSME
MUL_2015|M.ulcerans_Agy99           VELSAVNDPGNCVVAGPKDEIRAFSQRLNEAGIPVRRVRATHAFHSSSME
MAB_2256|M.abscessus_ATCC_1997      VSVAAVNGPEQIVVAGREEGIEALLSTGANVGVRCTRLPVNRGFHSALVD
MAV_1763|M.avium_104                VAAYNGPN---TVLSGPGADLEQIVARGASDGIRCSWLETSHAFHSELLD
MSMEG_0408|M.smegmatis_MC2_155      VGAYNGPN---TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLD
TH_4621|M.thermoresistible__bu      VVLSVIASPESTVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVD
                                    *      .    *:.*    :. :       *:    : .  . *:  ::

Mflv_3390|M.gilvum_PYR-GCK          PVVAEFTAFLSGLTLREPQIPLLSNVTGTTMSASEATNPSTWARQIRATV
Mvan_3123|M.vanbaalenii_PYR-1       PVVAEFGAFLSGVTLREPQIPLLSNITGTTMTAAEATNPSTWARQIRATV
Mb2960|M.bovis_AF2122/97            PMLGQFQEFLSRQQLRPPRTPLLSNLTGSWMSDQQVVDPASWTRQISSPI
Rv2935|M.tuberculosis_H37Rv         PMLGQFQEFLSRQQLRPPRTPLLSNLTGSWMSDQQVVDPASWTRQISSPI
MLBr_02353|M.leprae_Br4923          PMLREFSEFLSRQQLRVPNTPLLSNLTGTWMSEQQVTDPENWTRQISSTI
MMAR_1772|M.marinum_M               PMLGEFQEFLSRQQLRAPQTPLLSNLTGTWLSEQQVTDPATWARQISSTV
MUL_2015|M.ulcerans_Agy99           PMLGEFQEFLSRQQLRAPQTPLLSNLTGTWLSEQQVTDPATWARQISSTV
MAB_2256|M.abscessus_ATCC_1997      PAVSSFSAAVARMRLQQPQVPFISNVTGTWITGAQATEPEYWGRQLRETV
MAV_1763|M.avium_104                PVLDEFESYAAHLDFAVPTLPLVCNRTGTVLTTETPLDARYWRRHSRQPV
MSMEG_0408|M.smegmatis_MC2_155      PVLDEFEAYAAQFQFAAPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPV
TH_4621|M.thermoresistible__bu      PILDELEEILADLQPMTPTVPYYS-ATSYDPREKPVCDADYWVDNLRHEV
                                    * : .:    :      *  *  .  *.         :.  *  :    :

Mflv_3390|M.gilvum_PYR-GCK          RFADELDALLAA-PDRVLVEVGPGGTLTSSAGRHPRWSERHRAVRLMRHQ
Mvan_3123|M.vanbaalenii_PYR-1       RFADELDALLAA-PDRVLVEVGPGGTLTSSAGRHPKWTERHRAVRLMRHQ
Mb2960|M.bovis_AF2122/97            RFADELDVVLAA-PSRILVEVGPGGSLTGSAMRHPKWSTTHRTVRLMRHP
Rv2935|M.tuberculosis_H37Rv         RFADELDVVLAA-PSRILVEVGPGGSLTGSAMRHPKWSTTHRTVRLMRHP
MLBr_02353|M.leprae_Br4923          RFADELDVVLSQ-SGRVLVEVGPGGSLTGSAMRHPRWSSGHRAVRLMRHP
MMAR_1772|M.marinum_M               RFADELDVVLSQ-PNRILVEIGPGGSLTGSAIRHPKWSDGHRSVRLMRHP
MUL_2015|M.ulcerans_Agy99           RFADELDVVLSQ-PNRILVEIGPGGSLTGSAIRHPKWSDGHRSVRLMRHP
MAB_2256|M.abscessus_ATCC_1997      QFARGLTTLCAEYPDALLVEVGPGHTLRGIVAAN---TPASEVVSMLGDR
MAV_1763|M.avium_104                QFAESVRTVAAL-GCTVLMEIGPQPVLTG--AAVQVWPEHLAAPRAIVSL
MSMEG_0408|M.smegmatis_MC2_155      QFAESVRTVAAL-GCSVLMEIGPQPVLTG--AAVQVWPEHMAAPRAVASL
TH_4621|M.thermoresistible__bu      RFAAAVQAALED-GFRVFGELSPHPLLTR--AVEQTARGLDMPVAALPAM
                                    :**  : .        :: *:.*   *                   :   

Mflv_3390|M.gilvum_PYR-GCK          AQNRSDDDTFHLALGQLWAADVDVDWTQGDQDAADARTLVTLPGYPFARQ
Mvan_3123|M.vanbaalenii_PYR-1       AQNRNDHDTFLLALGQLWAADVEVDFNQG---AEEDRTLITLPGYPFAKQ
Mb2960|M.bovis_AF2122/97            LQDVDDRDTFLRALGELWSAGVEVDWTPR---RPAVPHLVSLPGYPFARQ
Rv2935|M.tuberculosis_H37Rv         LQDVDDRDTFLRALGELWSAGVEVDWTPR---RPAVPHLVSLPGYPFARQ
MLBr_02353|M.leprae_Br4923          LQNVDDHDTFLRALGELWSAGIEVDWAPQ---RSVMPHLVSLPGYPFARQ
MMAR_1772|M.marinum_M               IQNLDDRETFLRALGELWSAGVDVDWTPR---RAASPRIVSLPGYPFARQ
MUL_2015|M.ulcerans_Agy99           IQNLDDRETFLRALGELWSAGVDVDWTPR---RAASPRIVSLPGYPFARQ
MAB_2256|M.abscessus_ATCC_1997      TG--DSATVALAAAGRLWAGGAELAWQHFG----ASRPRVPLPTYPFERE
MAV_1763|M.avium_104                RKGVGDRRQIAEGLAAAYVSGHRPEFAALHR--RPRRK-LELPTYPFQRR
MSMEG_0408|M.smegmatis_MC2_155      RKGVADRRQIADALASAYVGGHRPDFAAVHR--QPRRP-VELPTYPFQRR
TH_4621|M.thermoresistible__bu      RREQEMPHGVRTMVGDLFAAGAAVDFAALYP--SGRLVDAPLPTWTRRKL
                                                  .  : ..    :               ** :.  : 

Mflv_3390|M.gilvum_PYR-GCK          RHWVEYN----ASSAWVANG--SGAAGVSATGAQAGSAAGGAGGGSSVEA
Mvan_3123|M.vanbaalenii_PYR-1       RHWVEHN----ANAAWLAGG--AGADGTAAAAGSAGVAPVAAGGTSTVEA
Mb2960|M.bovis_AF2122/97            RHWVEPNHTVWAQAPGANNG--SPAGTADGSTA--ATVDAARNGESQTEV
Rv2935|M.tuberculosis_H37Rv         RHWVEPNHTVWAQAPGANNG--SPAGTADGSTA--ATVDAARNGESQTEV
MLBr_02353|M.leprae_Br4923          RHWVEPRYTIWAQIPGASSG--SPVDSSVDS----ATVEGVRGGESQTEA
MMAR_1772|M.marinum_M               RHWVEPKHMAWAQIPTASNG--SSVGAKLGSGADSGIRGGAQTGESQTED
MUL_2015|M.ulcerans_Agy99           RHWVEPKHMAWAQIPTASNG--SSVGAKLGSGADSGIRGGAQTGESQTED
MAB_2256|M.abscessus_ATCC_1997      RLWMSPP--------RSVLD--KPVQAPIAPAVQVPLVTASTQTDVPDAA
MAV_1763|M.avium_104                RFWPKASGIAGIDGQGAAASGLLGSAKELASGDS--VYTSRLSVKSQPWL
MSMEG_0408|M.smegmatis_MC2_155      RFWPKASSIA-VDG-GTAASGILGSGKDLASGDT--IYTSRLSVKSQPWL
TH_4621|M.thermoresistible__bu      VLSRENGEQQTRGGCTITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWL
                                        .                                             

Mflv_3390|M.gilvum_PYR-GCK          SLQRIWAQCLGVNEIDRHANFFEIG-------------------------
Mvan_3123|M.vanbaalenii_PYR-1       KLARIWSQCLGLSDIDRNANFFEIG-------------------------
Mb2960|M.bovis_AF2122/97            TLQRIWSQCLGVSSVDRNANFFDLG-------------------------
Rv2935|M.tuberculosis_H37Rv         TLQRIWSQCLGVSSVDRNANFFDLG-------------------------
MLBr_02353|M.leprae_Br4923          TLQRIWSQCLGVSSVDRNANFFDLG-------------------------
MMAR_1772|M.marinum_M               VLQRIWSQCLGVGSVDRNANFFDMG-------------------------
MUL_2015|M.ulcerans_Agy99           VLQRIWSQCLGVGSVDRNANFFDMG-------------------------
MAB_2256|M.abscessus_ATCC_1997      VVEQIWCEALGVPSVESDDNFFDLG-------------------------
MAV_1763|M.avium_104                ADHVIYGTVVVPGATYAAMALAAVGPPARVQNVYFYEPIILPDKASREVQ
MSMEG_0408|M.smegmatis_MC2_155      ADHVIYGTVVVPGATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQ
TH_4621|M.thermoresistible__bu      ADHQIHTVAALPGAAYCEMALAAAREVIDSDGVEVRD-----VRFEQMLL
                                        *               :                             

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                LSLHPLQEG-GWSFRVDSRPYGVPDAEWSLNADGTV-VAGIEDEPAADP-
MSMEG_0408|M.smegmatis_MC2_155      LTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDAAADEQ
TH_4621|M.thermoresistible__bu      LDEQTEVSAVASAVEPGTLEFAVETAKDGEHERRATAVLGAADDTEPPQA
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          -------------------------------------------------G
Mvan_3123|M.vanbaalenii_PYR-1       -------------------------------------------------G
Mb2960|M.bovis_AF2122/97            -------------------------------------------------G
Rv2935|M.tuberculosis_H37Rv         -------------------------------------------------G
MLBr_02353|M.leprae_Br4923          -------------------------------------------------G
MMAR_1772|M.marinum_M               -------------------------------------------------G
MUL_2015|M.ulcerans_Agy99           -------------------------------------------------G
MAB_2256|M.abscessus_ATCC_1997      -------------------------------------------------G
MAV_1763|M.avium_104                ADHIDAVIERLDRNRPQLLFDSFAESELEWGTTWSTSLKSLWMGDGEAVG
MSMEG_0408|M.smegmatis_MC2_155      SDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVG
TH_4621|M.thermoresistible__bu      HDIDALLAEHPTRIEGDELRQWFDQRGVQFGPAFTG-LTAARIPEG-TVT
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          DSLVAISVAMTAGHAGLDLTPQDLYENQTVASLAKVLTARYAEGGLARQS
Mvan_3123|M.vanbaalenii_PYR-1       DSLIAISVAMTAGHEGLDLTPQDLYENQTVAALAKVLTARYAEGGLARQT
Mb2960|M.bovis_AF2122/97            DSLMAISIAMAAANEGLTITPQDLYEYPTLASLTAAVDASFASSGLAKP-
Rv2935|M.tuberculosis_H37Rv         DSLMAISIAMAAANEGLTITPQDLYEYPTLASLTAAVDASFASSGLAKP-
MLBr_02353|M.leprae_Br4923          DSLMAISISMAAANEGMTITPQDMYEHPTLASLTAAVDASFASSGLAKP-
MMAR_1772|M.marinum_M               DSLMAISIAMSAANEGLTITPQDLYEHPTLASLTAAIDASFASSGLAKP-
MUL_2015|M.ulcerans_Agy99           DSLMAISIAMSAANEGLTITPQDLYEHPTLASLTAAIDASFASSGLAKP-
MAB_2256|M.abscessus_ATCC_1997      DSLIAARVVTAIGER-----------CHIKVSVAELWDQGATLADLAELV
MAV_1763|M.avium_104                DVTVGDELAEHLGTEPMHPVLLDLCTGVVFPAFPALLAAEQGFNDLLLPL
MSMEG_0408|M.smegmatis_MC2_155      DILVGAELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPL
TH_4621|M.thermoresistible__bu      SVLAEVGLPGQIRSQQAPYGIHPALLDACFQSVAAHPDVQGAGSGLLLPL
                                    .      :                       :..          .*    

Mflv_3390|M.gilvum_PYR-GCK          ---------------------VDDSTSPPVPPNVAYFLEHGLRDVGRWRI
Mvan_3123|M.vanbaalenii_PYR-1       ---------------------LDDAVNPPVPPNVAYFLEHGLRDIGRWRI
Mb2960|M.bovis_AF2122/97            ---------------------PEAQANPAVPPNVTYFLDRGLRDTGRCRV
Rv2935|M.tuberculosis_H37Rv         ---------------------PEAQANPAVPPNVTYFLDRGLRDTGRCRV
MLBr_02353|M.leprae_Br4923          ---------------------PEAAAHPAVPPNIAYFLERGLCDTGRWRV
MMAR_1772|M.marinum_M               ---------------------PEADANPAVPPNIAYFLDRGLRDTGRWRV
MUL_2015|M.ulcerans_Agy99           ---------------------PEADANPAVPPNIAYFLDRGLRDTGRWRV
MAB_2256|M.abscessus_ATCC_1997      ---------------------ERRAINSKVGEQLK---------------
MAV_1763|M.avium_104                RYGQVSLREKMPRRFYCRGKWRPSALDSETQVFDIDFIDRDGRHLGGIRE
MSMEG_0408|M.smegmatis_MC2_155      RYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIRE
TH_4621|M.thermoresistible__bu      GVRRLQAFGPTRGARYCYARVT--DADGSKAEADLDVLDEHGNVLLRVQG
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          PVILGLRSDVGEDDVRAVLTAVTDAHDVLRVRLVERSGIWDQIIAEPGEF
Mvan_3123|M.vanbaalenii_PYR-1       PVILGLRSDVGEDDVRAVLTAVTEVHDALRVHLVERAGTWDQHIAEPGEF
Mb2960|M.bovis_AF2122/97            PLILRLDPKIGLPDIRAVLTAVVNHHDALRLHLVGNDGIWEQHIAAPAEF
Rv2935|M.tuberculosis_H37Rv         PLILRLDPKIGLPDIRAVLTAVVNHHDALRLHLVGNDGIWEQHIAAPAEF
MLBr_02353|M.leprae_Br4923          PLILRLDPKIGSDDIRAVLTAVVNHHDVLRLSLVDNDGMWEQHIAATGEF
MMAR_1772|M.marinum_M               PLILRLDPQVGPEDIRAVLSAVTNHHDALRLRLVENGGVWEQHIAAPADF
MUL_2015|M.ulcerans_Agy99           PLILRLDPQVGPEDIRAVLSAVTNHHDALRLRLVENGGVWEQHIAAPADF
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                FTVKRAPREALLRGLGGDATRLLYTLGWHEVPPQPSNDG---VANPSGTW
MSMEG_0408|M.smegmatis_MC2_155      FTVKRAPREALLRGLGGDATRLLYTLGWHEVPPPPSAD------DAVGTW
TH_4621|M.thermoresistible__bu      LLMGGAAADGDDRDRVLGERLLTIEWQRRDLPEADSAAGKWLLVSTSATA
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          TELASRELPSGVAAGSPQEREAVLAFLDEQVREH-QVVVPLTATLIRSGS
Mvan_3123|M.vanbaalenii_PYR-1       TELVARQLPEGLAAGSPQEREAVLGFLDEQVREH-QVVVPLAATFIRGVT
Mb2960|M.bovis_AF2122/97            TGLSNRSVPDGVAAGSPEERAAVLGILAELLEDQTDPNAPLAAVHIAAAH
Rv2935|M.tuberculosis_H37Rv         TGLSNRSVPNGVAAGSPEERAAVLGILAELLEDQTDPNAPLAAVHIAAAH
MLBr_02353|M.leprae_Br4923          TRLLTQTLPDGVAAGSAEERAVVSSILAELIASQSDLNEPLTAVQITTAH
MMAR_1772|M.marinum_M               TELATRQLPGDLAAGEADEHGAVSNIVAELIAEQGDSNAPLIAVHVTAPN
MUL_2015|M.ulcerans_Agy99           TELATRQLPDDLAADEADEHSAVSNIVAELIAEQGDSNAPLIAVHVTAPN
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                LIAGFDELGAQLPGCIPFDRNTDPESFGQLLARAEDRGGPVTGIVWRATQ
MSMEG_0408|M.smegmatis_MC2_155      LIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCAT
TH_4621|M.thermoresistible__bu      DVSATRLSDALKQAGAESTSMCWPQQADHADNVDRFRAGIADGVTGVVVL
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          GG--------------PSYLALSLHGIAGDVSGDSASRDVLLTDLFTAFN
Mvan_3123|M.vanbaalenii_PYR-1       GG--------------PSYLALSLHGIAG----DDVSRDVLLTDVFTAFS
Mb2960|M.bovis_AF2122/97            GG--------------PHYLCLAIHAMVT----DDSSRQILATDIVTAFG
Rv2935|M.tuberculosis_H37Rv         GG--------------PHYLCLAIHAMVT----DDSSRQILATDIVTAFG
MLBr_02353|M.leprae_Br4923          GG--------------PHYLGLAVHQMVI----DDASRQILGTDIITAFG
MMAR_1772|M.marinum_M               GG--------------AQYLGLALHEMVA----DDASRQLLGADIITAFA
MUL_2015|M.ulcerans_Agy99           GG--------------AQYLGLALHETVA----DDASRQLLGADIITAFA
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                SGGRES--SAESVARLETEIAGLLTAVHALQNADGSAVKLPGGLWIVTER
MSMEG_0408|M.smegmatis_MC2_155      PGRKESGSASAESARLEAEITNLLSAVHAAQ---GPSVKLPGGLWIVTEH
TH_4621|M.thermoresistible__bu      TGPKNGNPDDAAARRGSDYVRHLVRITRELAEIDGDAP----RLFVVTRG
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          QRMAGEEIVLAPVTASWREWSQRCAGLAGHPAVLDSRDYWLQTAHRSTLR
Mvan_3123|M.vanbaalenii_PYR-1       QRMAGEEIVLAPVPASWREWSQRCAGLASHPAVLDSRDYWLQTAGASTLR
Mb2960|M.bovis_AF2122/97            QRLAGEEITLEPVSTGWREWSLRCAALATHPAALDTRSYWIENSTKATLW
Rv2935|M.tuberculosis_H37Rv         QRLAGEEITLEPVSTGWREWSLRCAALATHPAALDTRSYWIENSTKATLW
MLBr_02353|M.leprae_Br4923          QRLAGEEITLEPVTTGWREWSLRCAALATHPAALDTRSFWIENANKVNLW
MMAR_1772|M.marinum_M               QRLGDQEIKLDPVTTGWRDWSVRCAALATHPAALDTRSYWIEQSTKANLW
MUL_2015|M.ulcerans_Agy99           QRLDDQEIKLDPVTTGWRDWSVRCAALATHPAALDTRSYWIEQSTKANLW
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                GVATESGEPVDPVQAALWGLGRTIVNEEPALRCRLVDSDGSEQAVRSLAG
MSMEG_0408|M.smegmatis_MC2_155      GVACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDLLAA
TH_4621|M.thermoresistible__bu      AQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIADDADLDRVAVQ
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          VAGG----EPADRPG--AADLERLSTMLSAAETGEFDDARRRLRLSAEEI
Mvan_3123|M.vanbaalenii_PYR-1       IAGP----EHSERPG--VDDVTRLSTALSAAETGEIDDARRRLRLPVEEI
Mb2960|M.bovis_AF2122/97            LADALPNAHTAHPPR--ADELTKLSSTLSVEQTSELDDGRRRFRRSIQTI
Rv2935|M.tuberculosis_H37Rv         LADALPNAHTAHPPR--ADELTKLSSTLSVEQTSELDDGRRRFRRSIQTI
MLBr_02353|M.leprae_Br4923          LADVSLNTDVIQPPG--ADDLIRMPCTLSVEQTSELDDARRRFRRSIQAI
MMAR_1772|M.marinum_M               LTDG----DAAQPPS--ATDLTKLPSVLNAEQTSELDDARRRFRRSIQTI
MUL_2015|M.ulcerans_Agy99           LTDG----DAAQPPS--ATDLTKLPSVLNAEQTSELDDARRRFRRSIQTI
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                LLGAP-LDEPELAVR---QGKLLASRLLPWARSGHLAVPRGTDYVLAPTE
MSMEG_0408|M.smegmatis_MC2_155      LLAAPGIQEPEIAVR---QGKLLASRLLPWARSGHLTLPRGGDFVLAPTE
TH_4621|M.thermoresistible__bu      LLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQAVVDCERDGMRLEIRT
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          LLAALGRAVAVTVGEGAVAVDLGGRGRSVLKPDVDLARTVGSFAALHPVV
Mvan_3123|M.vanbaalenii_PYR-1       LLAALGRAVAATVGEGAVSVDLGGRGRSVLKPDVDLQRTVGWFTTIHPVV
Mb2960|M.bovis_AF2122/97            LLAALGRTIAQTVGEGVVAVELEGEGRSVLRPDVDLRRTVGWFTTYYPVP
Rv2935|M.tuberculosis_H37Rv         LLAALGRTIAQTVGEGVVAVELEGEGRSVLRPDVDLRRTVGWFTTYYPVP
MLBr_02353|M.leprae_Br4923          VLAALGRTIAQTVGDGVVAVELEGEGRSVLRPDVDVRRTIGWFTNYYPIP
MMAR_1772|M.marinum_M               LLAALGRTIAQTVGDGVVAVELDGEGRSVLRPDVDVRRTVGRFTTYYPVA
MUL_2015|M.ulcerans_Agy99           LLAALGRTIAQTVGDGVVAVELDGEGRSVLRPDVDVRRTVGRFTTYYPVA
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                RGAIDNLRLIEQEAPPPAEGCVQVRVEAGGLNFREVLNVLGLYPGDPG--
MSMEG_0408|M.smegmatis_MC2_155      RGAIDNLRLTETDVPEPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPG--
TH_4621|M.thermoresistible__bu      PGDLETMELAAFDRVPPGPGQIEVAVTASSINFADVLIAFGRYPTFDGRR
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          LT-ASGQ--TASAALAEVRQTLDAVPHYGIGYGLLRYLYAPTARLLGDGR
Mvan_3123|M.vanbaalenii_PYR-1       LT-AARQG-SATQALGDVRETLKAVPHYGIGYGLLRYLYAPTARVLGASR
Mb2960|M.bovis_AF2122/97            LACATGLG--ALAQLDAVHNTLKSVPHYGIGYGLLRYVYAPTGRVLGAQR
Rv2935|M.tuberculosis_H37Rv         LACATGLG--ALAQLDAVHNTLKSVPHYGIGYGLLRYVYAPTGRVLGAQR
MLBr_02353|M.leprae_Br4923          LVCVKGQG--ALAQLDAVHNTLKSIPHYGIGYGLLRYMYAPTGRVFSAQR
MMAR_1772|M.marinum_M               LTCATGQGAAALKGLDAVHDTLKSVPHYGIGYGLLRYLYAPTGRVLGAQR
MUL_2015|M.ulcerans_Agy99           LTCATGQGAAALKGLDAVHDTLKSVPHYGIGYGLLRYLYAPTGRVLGAQR
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                -PLGGDFAGTVTQLGSGVTGLEVGTRVYGFMQG-AFASRFNVPVQLLAPI
MSMEG_0408|M.smegmatis_MC2_155      -PIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQG-AFASRFNVPAQFLAPI
TH_4621|M.thermoresistible__bu      PQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGCWSTFVTCDADLAVPL
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          PADILFSHVGTIPDAPADQPD--DAPVRFDPDTAMPIRDALPGLGHALEV
Mvan_3123|M.vanbaalenii_PYR-1       PADILFSHIGTIPEVPAEQPD--DAPVRFDADTAMPIRDALPGLGHAVEL
Mb2960|M.bovis_AF2122/97            TPDIHFRYAGVIPELPSG-----DAPVQFDSDMTLPVREPIPGMGHAIEL
Rv2935|M.tuberculosis_H37Rv         TPDIHFRYAGVIPELPSG-----DAPVQFDSDMTLPVREPIPGMGHAIEL
MLBr_02353|M.leprae_Br4923          TPDIHFRYVGVVPEPPSV-----DATVQFDSDMTIPVQEPVPGMGHAIEL
MMAR_1772|M.marinum_M               TPDIHFRYAGTIPELPPV-----DAPVQFDSDLAMPVREPLPGLGHAVEI
MUL_2015|M.ulcerans_Agy99           TPDIHFRYAGTIPELPPV-----DAPVQFDSDLAMPVREPLPGLGHAVEI
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                PDGVSAVDAATIPAAALTARL-AFDWAQLKPGDRVLIHAASGGVGLAAIQ
MSMEG_0408|M.smegmatis_MC2_155      PDGIGAVEAATIPAAALTVRL-AFDWAQLKPGDKVLIHAASGGVGLAAIQ
TH_4621|M.thermoresistible__bu      PDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLIHSATGGVGLAAIA
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          RIYRTGGELHLDWWY--DIRRLGPTDVESFSRQYSAAVLDISREALAEED
Mvan_3123|M.vanbaalenii_PYR-1       RVYRAAGVLHLDWWY--DNRRLGPTDVESFARQYSEALLDVTRDALAEED
Mb2960|M.bovis_AF2122/97            RVYRFGGSLHLDWWY--DTRRIPAATAEALERTFPLALSALIQEAIAAEH
Rv2935|M.tuberculosis_H37Rv         RVYRFGGSLHLDWWY--DTRRIPAATAEALERTFPLALSALIQEAIAAEH
MLBr_02353|M.leprae_Br4923          RTYRFGGSLHLDWWY--DIRRIPQVTAEALAQSFPVTLSKLIQEGIATQK
MMAR_1772|M.marinum_M               RAYRSGSSLHVDWWY--DTRRITAETATALARSFPTALSELIQESIAAEQ
MUL_2015|M.ulcerans_Agy99           RAYRSGSSLHVDWWY--DTRRITAETATALARSFPTALSELIQESIAAEQ
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                LAQRHGATVFATAST-YKRATLRKLGVEYVYDSRSTDFADQILADTDGAG
MSMEG_0408|M.smegmatis_MC2_155      MAQQSGAEVFATAST-FKRSTLRRLGVKYVYDSRTTDFADQILADTNGAG
TH_4621|M.thermoresistible__bu      IARSVGAQIYATAGSPARRDLLRDMGIEHVYDSRSTAFADEIRRDTDGYG
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          TDAAGDELA-------LVDLS-----------------------------
Mvan_3123|M.vanbaalenii_PYR-1       TDAAGDELA-------LVDLS-----------------------------
Mb2960|M.bovis_AF2122/97            TEHDDSEIVGEPEAGALVDLSSMDAG------------------------
Rv2935|M.tuberculosis_H37Rv         TEHDDSEIVGEPEAGALVDLSSMDAG------------------------
MLBr_02353|M.leprae_Br4923          DAHDESEMAGAPQAGVLVDLSTLDAG------------------------
MMAR_1772|M.marinum_M               EERDEDEKVGVIEAGALVDLSSLDAG------------------------
MUL_2015|M.ulcerans_Agy99           EERDEDEKVGVIEAGALVDLPSLDAG------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                VDVVLNSLTNEGFIEATVRATAQHGRFVEIAKRDIW--TREQMAAARPDI
MSMEG_0408|M.smegmatis_MC2_155      VDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIW--SHEQMAEARPDI
TH_4621|M.thermoresistible__bu      VDVVLNSLP-GAAQRAGLELLSFGGRFIEIGKRDIYGDTRLGLFPFRRNL
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                AYEIVALDWACVEQPEHIHALLTEVSDGLASGEWRPLPAEIYPLAEAKTA
MSMEG_0408|M.smegmatis_MC2_155      AYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIYPITEARSA
TH_4621|M.thermoresistible__bu      AFHGVDLGLMADSHPHKIRELLETVYRLTADGVLPMPQSTHYPLAEAATA
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                FRRMQQARHIGKIVLQMPKP------------LQPRGDRSYLITGGLGAI
MSMEG_0408|M.smegmatis_MC2_155      FRRMQQARHIGKIVLQVPKP------------LQPQQDRSYLITGGLGAI
TH_4621|M.thermoresistible__bu      IRVMSAAEHVGKLVLDVPHTGRADVVVPPEQASPFRSDGAYIVTGGMGGL
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                GLHLAAYLAQLGAGEIVLTSRRAPDAAAWRAIDDITERYRCRVHTFAADV
MSMEG_0408|M.smegmatis_MC2_155      GLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADV
TH_4621|M.thermoresistible__bu      GLYLAGEMAAAGAGCIVLNGRSAPSGEALRTIEQLRAAGTEVIVECGXXX
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                GDAAQVEQLLARIRAELPPLAGVAHLAGVLDDALLSQQSPERFRVALAPK
MSMEG_0408|M.smegmatis_MC2_155      GDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPK
TH_4621|M.thermoresistible__bu      --------------------RGQPVEVAVPTELRHADEHPDRRGAQLCDE
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                AFG-ASYLDHATRTDDLDFFIVSSSVSSLLGSPGQANYSTANAWLDGLVA
MSMEG_0408|M.smegmatis_MC2_155      AYG-ASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANYATANAMLDGLVA
TH_4621|M.thermoresistible__bu      FARGEQGAQRNQHRTDAGEGQRDAHPPGAVGHDQPDPGALSDTGLDERGG
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                ARQARGLPATGVNLGPWAQGGMASSEAARANIGAQGLIPLEPTAALAALA
MSMEG_0408|M.smegmatis_MC2_155      KRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPLDPSAALHALA
TH_4621|M.thermoresistible__bu      QFPGVGVQIPVADPG----VGIDHRGAVRVDSGVPAQQGVDGEVVRHRTL
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                EVVANGTGQATVIKANWQRAAKLLGGARPPILDLVLPSAVGEASGDSELL
MSMEG_0408|M.smegmatis_MC2_155      EVIANGSGQATVLKANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELL
TH_4621|M.thermoresistible__bu      SSVRSGRSSRWTAPGSRCGSGRRYGGESCRRTTGPAAGAAARRGRTRRRR
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                KQLQEIPVAQRAAFITEFLQREVQGFLRLAQPPAATSRFLDLGTDSLMAV
MSMEG_0408|M.smegmatis_MC2_155      KQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTDSLMAI
TH_4621|M.thermoresistible__bu      RPRRPPPPPDRVRHRAGPAHGPVRR-------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3123|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2960|M.bovis_AF2122/97            --------------------------------------------------
Rv2935|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_02353|M.leprae_Br4923          --------------------------------------------------
MMAR_1772|M.marinum_M               --------------------------------------------------
MUL_2015|M.ulcerans_Agy99           --------------------------------------------------
MAB_2256|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1763|M.avium_104                ELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYLAGQLPDAESEPGAAVA
MSMEG_0408|M.smegmatis_MC2_155      ELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEAPETA---
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_3390|M.gilvum_PYR-GCK          -------------------------
Mvan_3123|M.vanbaalenii_PYR-1       -------------------------
Mb2960|M.bovis_AF2122/97            -------------------------
Rv2935|M.tuberculosis_H37Rv         -------------------------
MLBr_02353|M.leprae_Br4923          -------------------------
MMAR_1772|M.marinum_M               -------------------------
MUL_2015|M.ulcerans_Agy99           -------------------------
MAB_2256|M.abscessus_ATCC_1997      -------------------------
MAV_1763|M.avium_104                ANPNPGSETGTGEAEPEREAAPEPS
MSMEG_0408|M.smegmatis_MC2_155      -------------------------
TH_4621|M.thermoresistible__bu      -------------------------