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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_3699 | - | - | 100% (396) | thiolase |
M. thermoresistible (build 8) | TH_3906 | - | 2e-61 | 36.34% (388) | PUTATIVE Thiolase |
M. thermoresistible (build 8) | TH_2654 | - | 4e-61 | 37.63% (388) | PUTATIVE Thiolase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0938c | - | 9e-40 | 34.40% (343) | acetyl-CoA acetyltransferase |
M. gilvum PYR-GCK | Mflv_2505 | - | 2e-57 | 36.22% (381) | thiolase |
M. tuberculosis H37Rv | Rv0914c | - | 9e-40 | 34.40% (343) | acetyl-CoA acetyltransferase |
M. leprae Br4923 | MLBr_01158 | fadA4 | 3e-10 | 21.96% (378) | acetyl-CoA acetyltransferase |
M. abscessus ATCC 19977 | MAB_1864 | - | 5e-42 | 32.91% (398) | lipid-transfer protein |
M. marinum M | MMAR_0142 | ltp1_1 | 1e-40 | 32.14% (392) | lipid-transfer protein Ltp1_1 |
M. avium 104 | MAV_5079 | - | 0.0 | 84.34% (396) | acetyl-CoA acetyltransferase |
M. smegmatis MC2 155 | MSMEG_5608 | - | 7e-41 | 33.99% (406) | acetyl-CoA acetyltransferase |
M. ulcerans Agy99 | MUL_4955 | ltp1_1 | 1e-40 | 32.14% (392) | lipid-transfer protein Ltp1_1 |
M. vanbaalenii PYR-1 | Mvan_4153 | - | 2e-54 | 35.70% (381) | thiolase family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0938c|M.bovis_AF2122/97 -----MDDGVWILGGYQSDFARNLSKENRDFADLTREVVDGTLTAAK--V Rv0914c|M.tuberculosis_H37Rv -----MDDGVWILGGYQSDFARNLSKENRDFADLTREVVDGTLTAAK--V MSMEG_5608|M.smegmatis_MC2_155 -----MEN-VWVLGGYQSDFARNLTRENLDFADLTREVVENTLAHAK--I TH_3699|M.thermoresistible__bu MASNGIAGKVAVVGMGCTRFG---ERWDASADDLILEAYAEALDSAG--I MAV_5079|M.avium_104 MPSNGIAGKVAVVAMGCSHFG---ERWDASTEDLILEAYQECLDSVPN-L Mflv_2505|M.gilvum_PYR-GCK ------MRRAAIVGAGMTPFA---EHFALGIKDLIPMAFSACASSVDKGL Mvan_4153|M.vanbaalenii_PYR-1 ------MRRVAIVGAGMTPFG---EHFALGMKDLLPMAFSECARTVDKGL MMAR_0142|M.marinum_M ---MSASDEIWILGIRMTKFG---KHPDLDTVDLAAQAAMSALDDAG--V MUL_4955|M.ulcerans_Agy99 ---MSASDEIWILGIRMTKFG---KHPDLDTVDLAAQAAMSALDDAG--V MAB_1864|M.abscessus_ATCC_1997 ---MKQQNKVFVVGVGMTKFEKPGRREGWDYPAMVKEAGTKALEDAG--V MLBr_01158|M.leprae_Br4923 -----MTTSVIVTGARTPIGKLMGSLKDFSASDLGAITIAAALKKAN--V : . . . : . . : Mb0938c|M.bovis_AF2122/97 DAADLAAAGVVHVANAFGEMFARQGHLGAMPATVCDD--LWDTPATRHEA Rv0914c|M.tuberculosis_H37Rv DAADLAAAGVVHVANAFGEMFARQGHLGAMPATVCDD--LWDTPATRHEA MSMEG_5608|M.smegmatis_MC2_155 DASDIG---VVHVANAFGELFARQGHLGAMPATVHEG--LWDTPSSRHEA TH_3699|M.thermoresistible__bu SRDDID-------AYWLGTLSSGLGGLT--LSRAIG---SDDKPVTRVEN MAV_5079|M.avium_104 GADDVD-------AFWLGTLSSGLGGLT--LSRAIG---NDDKPVTRVEN Mflv_2505|M.gilvum_PYR-GCK AKDDLQ-------AAWIGAMGTADGFPSGILADTLG---LPNLPVTRVEN Mvan_4153|M.vanbaalenii_PYR-1 SKADLQ-------AAWFGAMGTADGFPSGILADTLG---LPELPVTRVEN MMAR_0142|M.marinum_M SMADIG-------VLAAGNLMAANAGIGQQLQKQIG---QTGIPVYNVAN MUL_4955|M.ulcerans_Agy99 SMADIG-------VLAAGNLMAANAGIGQQLQKQIG---QTGIPVYNVAN MAB_1864|M.abscessus_ATCC_1997 QYPEIE-------QAFIGNVYG-DSCSGHRALYELG---HTGIPIYNVNS MLBr_01158|M.leprae_Br4923 APSIVQ-------YVIIGQVLTAGAGQMPARQAAVAAGIGWDVPALTINK : * : . * Mb0938c|M.bovis_AF2122/97 ACASGSVATLAAMADLRSGAYRVALVVGLELEKTVPGDT-------AAEH Rv0914c|M.tuberculosis_H37Rv ACASGSVATLAAMADLRSGAYRVALVVGLELEKTVPGDT-------AAEH MSMEG_5608|M.smegmatis_MC2_155 ACASGSVAALAAIADLRSGAYDTALVVGVELEKTVPGDD-------AAAN TH_3699|M.thermoresistible__bu FCATGSEAFRNACYAVASGAYDIAMAVGVEKLKDSGYSG-------LLRQ MAV_5079|M.avium_104 FCATGSEAFRNACYAVAAGAYDVAMALGVEKLKDSGYSG-------LLRQ Mflv_2505|M.gilvum_PYR-GCK SCATGHDAIRNALFGVSSGAFDVALVIGADKLRDTTSAG-------MLWE Mvan_4153|M.vanbaalenii_PYR-1 SCATGHDAIRNALFGIASGAFDVALVMGADKLRDTTSAE-------MLWE MMAR_0142|M.marinum_M ACATGATALRTAIMAVKAGEVDYGMAVGVEKLSGAGLLGGGGKKKSDADV MUL_4955|M.ulcerans_Agy99 ACATGATALRTAIMAVKAGEVDYGMAVGVEKLSGAGLLGGGGKKKSDADV MAB_1864|M.abscessus_ATCC_1997 NCSTGSTALFMAANAIRSGQSDVVMAAGFEKME-PGSLG-----MKFSDR MLBr_01158|M.leprae_Br4923 MCLSGLDAIALADQLIRAGEFDVVVAGGQESMTKAPHLL----------- * :* * * : :* :. * : Mb0938c|M.bovis_AF2122/97 LSAAAWTGHEGAEAR----YLWPSMFAQVADEYDRRYG----LDDTHLRA Rv0914c|M.tuberculosis_H37Rv LSAAAWTGHEGAEAR----YLWPSMFAQVADEYDRRYG----LDDTHLRA MSMEG_5608|M.smegmatis_MC2_155 LGTAAWTGHEGADAT----YMWPWMFSKVADEYDRRYC----LDPAHLRV TH_3699|M.thermoresistible__bu DPPGD---GTAPEIS----MTAPAAFSMLDPAYCARYGVHPDEMRAAMTH MAV_5079|M.avium_104 DPPGD---GTAPELS----MTAPAAFSMLDPAYCARHGVHPDEMRAAMTH Mflv_2505|M.gilvum_PYR-GCK WEAMARDMAWDYPLG----LVAPAGFALHVRRYLHES----PATEEHLAM Mvan_4153|M.vanbaalenii_PYR-1 WEAMARDMAWDYPLG----LVAPAGFALHVRRYLHES----PATEEHLAM MMAR_0142|M.marinum_M WTPAGRYGAVAPVDGRIGTETMPGVFAQIGTEYGHKYGG---TSFELFAK MUL_4955|M.ulcerans_Agy99 WTPAGRYGAVAPVDGRIGTETMPGVFAQIGTEYGHKYGG---TSFELFAK MAB_1864|M.abscessus_ATCC_1997 ESPLQPHIMALGELSQPQFPMTAWMFAAAAEEYMREYG----LTAEQLAW MLBr_01158|M.leprae_Br4923 --MDSRSGYKYGDVT----IVDHLAYDGLHDVFTNQPMGALTEQRNDVEK : : . . Mb0938c|M.bovis_AF2122/97 IAQLNFANARRNPNAQTRGWTIPDPITDDDATNPLTEGRLRRFDCSQMTD Rv0914c|M.tuberculosis_H37Rv IAQLNFANARRNPNAQTRGWTIPDPITDDDATNPLTEGRLRRFDCSQMTD MSMEG_5608|M.smegmatis_MC2_155 IAAVNFANARRNPNAQTRTWNVPDPLTDDDATNPVVEGRIRRFDCSQMTD TH_3699|M.thermoresistible__bu VAWKNHDNGSRNPKAQFR----SGVSKETIDKAVKVAGRLGVFDCSGVSD MAV_5079|M.avium_104 VAWKNHDNGTRNPKAQFR----SPVSRDTIDNAPKVAGRLGVFDCSGISD Mflv_2505|M.gilvum_PYR-GCK VAVKNHRHGVNNPKARLR----FEITMEQALNAPTVVTPFRLYDCAPQSD Mvan_4153|M.vanbaalenii_PYR-1 VAVKNHRHGVNNTKARLR----FEITMEQALNAPTVVTPFRLYDCAPQSD MMAR_0142|M.marinum_M ISEKNHAHSTLNPLAAYQ----KRFTLEQIMNDVMIAYPNTRPMCSANCD MUL_4955|M.ulcerans_Agy99 ISEKNHAHSTLNPLAAYQ----KRFTLEQIMNDVMIAYPNTRPMCSANCD MAB_1864|M.abscessus_ATCC_1997 IGYKNHKHSVNNPYSQFQ----DEYSLEDILSSRTIVGPLTKLQCSPTSD MLBr_01158|M.leprae_Br4923 FTRQEQDEFAARSHQKAAAAWKDGVFADEVVP---VSIPQSKGDSLQFTE . : . .. : . : Mb0938c|M.bovis_AF2122/97 GGAGLVLVSDAYLRDHRDARPIGRIDGWGHRTVGLGLRQKLDRVAQGDSA Rv0914c|M.tuberculosis_H37Rv GGAGLVLVSDAYLRDHRDARPIGRIDGWGHRTVGLGLRQKLDRVAQGDSA MSMEG_5608|M.smegmatis_MC2_155 GGAGVVLVTDRWLRAHPGVTPQARIAGWGHRTVGLGLQQKIDR---ADAD TH_3699|M.thermoresistible__bu GAACAVIVPADRAHEYTDTPMYVRALSLVSGSA----RGAVDAGYDYTTF MAV_5079|M.avium_104 GAACALIVPAERAREYTDTPMYVEALSLIAGSA----RASMDPGYDFTTF Mflv_2505|M.gilvum_PYR-GCK GAAALVIASEDVVDKFTDRPVWIRGVGLGLDSV----MHQHKP--DLTTF Mvan_4153|M.vanbaalenii_PYR-1 GAAALVIAADDVVDRFTDRPVWITGVGLGLDSV----MHQHKP--DLTTF MMAR_0142|M.marinum_M GAAAAIVCNGETLKSLSARQRRRAVKVSASVLT----TDPYEPGCQVLPN MUL_4955|M.ulcerans_Agy99 GAAAAIVCNGETLKSLSARQRRRAVKVSASVLT----TDPYEPGCQVLPN MAB_1864|M.abscessus_ATCC_1997 GSAAAIVASEEFVDTHGLADQAVEIVGQATVTD----REDTFDGTAAGIV MLBr_01158|M.leprae_Br4923 DEGIRANTSAESLAGLKPAFRCGGTITPGSASQISDGAATVVVMNKEKAQ . . Mb0938c|M.bovis_AF2122/97 PYLLPHVRATVLDALRRARVTLDDLDGIEVHDCFTPSEYLAIDHIGLTGP Rv0914c|M.tuberculosis_H37Rv PYLLPHVRATVLDALRRARVTLDDLDGIEVHDCFTPSEYLAIDHIGLTGP MSMEG_5608|M.smegmatis_MC2_155 PYLLPHVRGAVQDAFGRAQVTLDDIDGFEVHDCFTPSEYLAIDHIGLTGP TH_3699|M.thermoresistible__bu PEVVR--SARDAYAQAGIDDPATQLSFAEVHDCFTPTEIVLMEDLGFTEP MAV_5079|M.avium_104 PEVVK--SAKDAYTQAGIEHPARELSLAEVHDCFTPTEIVLMEDLGFSVA Mflv_2505|M.gilvum_PYR-GCK PATTR--AAKQAFAMAGMTP--SDVDVAEVHDFLTGIELMSYEDLGFAEK Mvan_4153|M.vanbaalenii_PYR-1 PATTR--AAKQAFAMAGRSP--SDVDVAEVHDFLTGIELMSYEDLGFAER MMAR_0142|M.marinum_M VNTLTRNAAKTAYEQAGVGP--SDLDLVELHDCFATAELVHYDNLMLCEQ MUL_4955|M.ulcerans_Agy99 VNTLTRNAAKTAYEQAGVGP--SDLDLVELHDCFATAELVHYDNLMLCEQ MAB_1864|M.abscessus_ATCC_1997 GANMNKAAIASVYAQAQIGP--DDLDVVELHDCFSANEILVYEALGFCEP MLBr_01158|M.leprae_Br4923 QLGLTWLVEIGAHGVVAGPDSTLQSQPANAIKKAVDREGISVEQLDVVEI : . : . * : : : . Mb0938c|M.bovis_AF2122/97 GESWKAIENGEIEIGGRLP--INPSGGLIGGGHPVGASGVRMLLDAAKQV Rv0914c|M.tuberculosis_H37Rv GESWKAIENGEIEIGGRLP--INPSGGLIGGGHPVGASGVRMLLDAAKQV MSMEG_5608|M.smegmatis_MC2_155 GESWKAIENGEIEISGRLP--INPSGGLIGGGHPVGASGVRMLLDATKQV TH_3699|M.thermoresistible__bu GRAYKDVLSGEFDADGRLP--VNIDGGLKSFGHPVGASGLRMLYEAWLQF MAV_5079|M.avium_104 GNAWKDVLSGEFDADGRLP--VNPDGGLKSFGHPVGASGLRMLYEAWLQF Mflv_2505|M.gilvum_PYR-GCK LGGYKLLEAEVTSVGGALP--VNPSGGLKAKGHPPGATGVAQCVELFAQL Mvan_4153|M.vanbaalenii_PYR-1 LGGYKLLEAEVTSLGGALP--VNPSGGLKAKGHPPGATGVAQCVELFAQL MMAR_0142|M.marinum_M GGAADFFESGAPWRDGSTP--VNVSGGLQSKGHPIAATGIANVWEICHHL MUL_4955|M.ulcerans_Agy99 GGAADFFESGAPWRHGSTP--VNVSGGLQSKGHPIAATGIANVWEICHQL MAB_1864|M.abscessus_ATCC_1997 GAAGKLIDNQDTTFGGKWV--VNPSGGLISKGHPLGATGLAQCAELNWQL MLBr_01158|M.leprae_Br4923 NEAFAAVALASARELGIAPELVNVNGGAIAVGHPLGMSGARITLHVALEL . . * :* .** . *** . :* . .. Mb0938c|M.bovis_AF2122/97 SGIAGDYQVENAE----AFGTLNFGGSTATTVSFVVSTTRGS---- Rv0914c|M.tuberculosis_H37Rv SGIAGDYQVENAE----AFGTLNFGGSTATTVSFVVSTTRGS---- MSMEG_5608|M.smegmatis_MC2_155 SASAGEYQVEAAK----TFGTLNFGGSTATTVSFVVTAGKE----- TH_3699|M.thermoresistible__bu RGAAGERQLAEPH----TALTHNLGGRPGGCVSFVSVVGRDR---- MAV_5079|M.avium_104 GGRAGARQLSDPH----TALTHNLGGRPGGCVSFVSIVSRTRRKRV Mflv_2505|M.gilvum_PYR-GCK RGEAVN-QVDGAR----IGLAHNIGG--PTAVAAVTILEGPDGG-- Mvan_4153|M.vanbaalenii_PYR-1 RGEAVN-QVDGAR----IGLAHNIGG--PTAVSAVTILEGPSGN-- MMAR_0142|M.marinum_M RGEAGDRQIDNAK----VGLAHVIGLGSACGVHILERSAA------ MUL_4955|M.ulcerans_Agy99 RGEAGDRQIDNAK----VGLAHVIGLGSACGVHILERSAA------ MAB_1864|M.abscessus_ATCC_1997 RGKADKRQVAGAATKDGVALQHNIGLGGSVVVTAYRPANR------ MLBr_01158|M.leprae_Br4923 ARRGSGYGVAALC-----------GAGGQGDALILRAV-------- . : * .