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M. thermoresistible (build 8) TH_3699 (-)

annotation: thiolase
coordinates: 28735 - 29922
length: 396

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3699--100% (396)thiolase
M. thermoresistible (build 8)TH_3906-2e-6136.34% (388) PUTATIVE Thiolase
M. thermoresistible (build 8)TH_2654-4e-6137.63% (388) PUTATIVE Thiolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0938c-9e-4034.40% (343) acetyl-CoA acetyltransferase
M. gilvum PYR-GCKMflv_2505-2e-5736.22% (381) thiolase
M. tuberculosis H37RvRv0914c-9e-4034.40% (343) acetyl-CoA acetyltransferase
M. leprae Br4923MLBr_01158fadA43e-1021.96% (378) acetyl-CoA acetyltransferase
M. abscessus ATCC 19977MAB_1864-5e-4232.91% (398) lipid-transfer protein
M. marinum MMMAR_0142ltp1_11e-4032.14% (392) lipid-transfer protein Ltp1_1
M. avium 104MAV_5079-0.084.34% (396) acetyl-CoA acetyltransferase
M. smegmatis MC2 155MSMEG_5608-7e-4133.99% (406) acetyl-CoA acetyltransferase
M. ulcerans Agy99MUL_4955ltp1_11e-4032.14% (392) lipid-transfer protein Ltp1_1
M. vanbaalenii PYR-1Mvan_4153-2e-5435.70% (381) thiolase family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0938c|M.bovis_AF2122/97           -----MDDGVWILGGYQSDFARNLSKENRDFADLTREVVDGTLTAAK--V
Rv0914c|M.tuberculosis_H37Rv        -----MDDGVWILGGYQSDFARNLSKENRDFADLTREVVDGTLTAAK--V
MSMEG_5608|M.smegmatis_MC2_155      -----MEN-VWVLGGYQSDFARNLTRENLDFADLTREVVENTLAHAK--I
TH_3699|M.thermoresistible__bu      MASNGIAGKVAVVGMGCTRFG---ERWDASADDLILEAYAEALDSAG--I
MAV_5079|M.avium_104                MPSNGIAGKVAVVAMGCSHFG---ERWDASTEDLILEAYQECLDSVPN-L
Mflv_2505|M.gilvum_PYR-GCK          ------MRRAAIVGAGMTPFA---EHFALGIKDLIPMAFSACASSVDKGL
Mvan_4153|M.vanbaalenii_PYR-1       ------MRRVAIVGAGMTPFG---EHFALGMKDLLPMAFSECARTVDKGL
MMAR_0142|M.marinum_M               ---MSASDEIWILGIRMTKFG---KHPDLDTVDLAAQAAMSALDDAG--V
MUL_4955|M.ulcerans_Agy99           ---MSASDEIWILGIRMTKFG---KHPDLDTVDLAAQAAMSALDDAG--V
MAB_1864|M.abscessus_ATCC_1997      ---MKQQNKVFVVGVGMTKFEKPGRREGWDYPAMVKEAGTKALEDAG--V
MLBr_01158|M.leprae_Br4923          -----MTTSVIVTGARTPIGKLMGSLKDFSASDLGAITIAAALKKAN--V
                                               : .   .           .   :   .       .   :

Mb0938c|M.bovis_AF2122/97           DAADLAAAGVVHVANAFGEMFARQGHLGAMPATVCDD--LWDTPATRHEA
Rv0914c|M.tuberculosis_H37Rv        DAADLAAAGVVHVANAFGEMFARQGHLGAMPATVCDD--LWDTPATRHEA
MSMEG_5608|M.smegmatis_MC2_155      DASDIG---VVHVANAFGELFARQGHLGAMPATVHEG--LWDTPSSRHEA
TH_3699|M.thermoresistible__bu      SRDDID-------AYWLGTLSSGLGGLT--LSRAIG---SDDKPVTRVEN
MAV_5079|M.avium_104                GADDVD-------AFWLGTLSSGLGGLT--LSRAIG---NDDKPVTRVEN
Mflv_2505|M.gilvum_PYR-GCK          AKDDLQ-------AAWIGAMGTADGFPSGILADTLG---LPNLPVTRVEN
Mvan_4153|M.vanbaalenii_PYR-1       SKADLQ-------AAWFGAMGTADGFPSGILADTLG---LPELPVTRVEN
MMAR_0142|M.marinum_M               SMADIG-------VLAAGNLMAANAGIGQQLQKQIG---QTGIPVYNVAN
MUL_4955|M.ulcerans_Agy99           SMADIG-------VLAAGNLMAANAGIGQQLQKQIG---QTGIPVYNVAN
MAB_1864|M.abscessus_ATCC_1997      QYPEIE-------QAFIGNVYG-DSCSGHRALYELG---HTGIPIYNVNS
MLBr_01158|M.leprae_Br4923          APSIVQ-------YVIIGQVLTAGAGQMPARQAAVAAGIGWDVPALTINK
                                        :            * :    .                  *      

Mb0938c|M.bovis_AF2122/97           ACASGSVATLAAMADLRSGAYRVALVVGLELEKTVPGDT-------AAEH
Rv0914c|M.tuberculosis_H37Rv        ACASGSVATLAAMADLRSGAYRVALVVGLELEKTVPGDT-------AAEH
MSMEG_5608|M.smegmatis_MC2_155      ACASGSVAALAAIADLRSGAYDTALVVGVELEKTVPGDD-------AAAN
TH_3699|M.thermoresistible__bu      FCATGSEAFRNACYAVASGAYDIAMAVGVEKLKDSGYSG-------LLRQ
MAV_5079|M.avium_104                FCATGSEAFRNACYAVAAGAYDVAMALGVEKLKDSGYSG-------LLRQ
Mflv_2505|M.gilvum_PYR-GCK          SCATGHDAIRNALFGVSSGAFDVALVIGADKLRDTTSAG-------MLWE
Mvan_4153|M.vanbaalenii_PYR-1       SCATGHDAIRNALFGIASGAFDVALVMGADKLRDTTSAE-------MLWE
MMAR_0142|M.marinum_M               ACATGATALRTAIMAVKAGEVDYGMAVGVEKLSGAGLLGGGGKKKSDADV
MUL_4955|M.ulcerans_Agy99           ACATGATALRTAIMAVKAGEVDYGMAVGVEKLSGAGLLGGGGKKKSDADV
MAB_1864|M.abscessus_ATCC_1997      NCSTGSTALFMAANAIRSGQSDVVMAAGFEKME-PGSLG-----MKFSDR
MLBr_01158|M.leprae_Br4923          MCLSGLDAIALADQLIRAGEFDVVVAGGQESMTKAPHLL-----------
                                     * :*  *   *   : :*     :. * :                    

Mb0938c|M.bovis_AF2122/97           LSAAAWTGHEGAEAR----YLWPSMFAQVADEYDRRYG----LDDTHLRA
Rv0914c|M.tuberculosis_H37Rv        LSAAAWTGHEGAEAR----YLWPSMFAQVADEYDRRYG----LDDTHLRA
MSMEG_5608|M.smegmatis_MC2_155      LGTAAWTGHEGADAT----YMWPWMFSKVADEYDRRYC----LDPAHLRV
TH_3699|M.thermoresistible__bu      DPPGD---GTAPEIS----MTAPAAFSMLDPAYCARYGVHPDEMRAAMTH
MAV_5079|M.avium_104                DPPGD---GTAPELS----MTAPAAFSMLDPAYCARHGVHPDEMRAAMTH
Mflv_2505|M.gilvum_PYR-GCK          WEAMARDMAWDYPLG----LVAPAGFALHVRRYLHES----PATEEHLAM
Mvan_4153|M.vanbaalenii_PYR-1       WEAMARDMAWDYPLG----LVAPAGFALHVRRYLHES----PATEEHLAM
MMAR_0142|M.marinum_M               WTPAGRYGAVAPVDGRIGTETMPGVFAQIGTEYGHKYGG---TSFELFAK
MUL_4955|M.ulcerans_Agy99           WTPAGRYGAVAPVDGRIGTETMPGVFAQIGTEYGHKYGG---TSFELFAK
MAB_1864|M.abscessus_ATCC_1997      ESPLQPHIMALGELSQPQFPMTAWMFAAAAEEYMREYG----LTAEQLAW
MLBr_01158|M.leprae_Br4923          --MDSRSGYKYGDVT----IVDHLAYDGLHDVFTNQPMGALTEQRNDVEK
                                                             :      :  .           .  

Mb0938c|M.bovis_AF2122/97           IAQLNFANARRNPNAQTRGWTIPDPITDDDATNPLTEGRLRRFDCSQMTD
Rv0914c|M.tuberculosis_H37Rv        IAQLNFANARRNPNAQTRGWTIPDPITDDDATNPLTEGRLRRFDCSQMTD
MSMEG_5608|M.smegmatis_MC2_155      IAAVNFANARRNPNAQTRTWNVPDPLTDDDATNPVVEGRIRRFDCSQMTD
TH_3699|M.thermoresistible__bu      VAWKNHDNGSRNPKAQFR----SGVSKETIDKAVKVAGRLGVFDCSGVSD
MAV_5079|M.avium_104                VAWKNHDNGTRNPKAQFR----SPVSRDTIDNAPKVAGRLGVFDCSGISD
Mflv_2505|M.gilvum_PYR-GCK          VAVKNHRHGVNNPKARLR----FEITMEQALNAPTVVTPFRLYDCAPQSD
Mvan_4153|M.vanbaalenii_PYR-1       VAVKNHRHGVNNTKARLR----FEITMEQALNAPTVVTPFRLYDCAPQSD
MMAR_0142|M.marinum_M               ISEKNHAHSTLNPLAAYQ----KRFTLEQIMNDVMIAYPNTRPMCSANCD
MUL_4955|M.ulcerans_Agy99           ISEKNHAHSTLNPLAAYQ----KRFTLEQIMNDVMIAYPNTRPMCSANCD
MAB_1864|M.abscessus_ATCC_1997      IGYKNHKHSVNNPYSQFQ----DEYSLEDILSSRTIVGPLTKLQCSPTSD
MLBr_01158|M.leprae_Br4923          FTRQEQDEFAARSHQKAAAAWKDGVFADEVVP---VSIPQSKGDSLQFTE
                                    .   :  .   ..              :                .    :

Mb0938c|M.bovis_AF2122/97           GGAGLVLVSDAYLRDHRDARPIGRIDGWGHRTVGLGLRQKLDRVAQGDSA
Rv0914c|M.tuberculosis_H37Rv        GGAGLVLVSDAYLRDHRDARPIGRIDGWGHRTVGLGLRQKLDRVAQGDSA
MSMEG_5608|M.smegmatis_MC2_155      GGAGVVLVTDRWLRAHPGVTPQARIAGWGHRTVGLGLQQKIDR---ADAD
TH_3699|M.thermoresistible__bu      GAACAVIVPADRAHEYTDTPMYVRALSLVSGSA----RGAVDAGYDYTTF
MAV_5079|M.avium_104                GAACALIVPAERAREYTDTPMYVEALSLIAGSA----RASMDPGYDFTTF
Mflv_2505|M.gilvum_PYR-GCK          GAAALVIASEDVVDKFTDRPVWIRGVGLGLDSV----MHQHKP--DLTTF
Mvan_4153|M.vanbaalenii_PYR-1       GAAALVIAADDVVDRFTDRPVWITGVGLGLDSV----MHQHKP--DLTTF
MMAR_0142|M.marinum_M               GAAAAIVCNGETLKSLSARQRRRAVKVSASVLT----TDPYEPGCQVLPN
MUL_4955|M.ulcerans_Agy99           GAAAAIVCNGETLKSLSARQRRRAVKVSASVLT----TDPYEPGCQVLPN
MAB_1864|M.abscessus_ATCC_1997      GSAAAIVASEEFVDTHGLADQAVEIVGQATVTD----REDTFDGTAAGIV
MLBr_01158|M.leprae_Br4923          DEGIRANTSAESLAGLKPAFRCGGTITPGSASQISDGAATVVVMNKEKAQ
                                    . .                                               

Mb0938c|M.bovis_AF2122/97           PYLLPHVRATVLDALRRARVTLDDLDGIEVHDCFTPSEYLAIDHIGLTGP
Rv0914c|M.tuberculosis_H37Rv        PYLLPHVRATVLDALRRARVTLDDLDGIEVHDCFTPSEYLAIDHIGLTGP
MSMEG_5608|M.smegmatis_MC2_155      PYLLPHVRGAVQDAFGRAQVTLDDIDGFEVHDCFTPSEYLAIDHIGLTGP
TH_3699|M.thermoresistible__bu      PEVVR--SARDAYAQAGIDDPATQLSFAEVHDCFTPTEIVLMEDLGFTEP
MAV_5079|M.avium_104                PEVVK--SAKDAYTQAGIEHPARELSLAEVHDCFTPTEIVLMEDLGFSVA
Mflv_2505|M.gilvum_PYR-GCK          PATTR--AAKQAFAMAGMTP--SDVDVAEVHDFLTGIELMSYEDLGFAEK
Mvan_4153|M.vanbaalenii_PYR-1       PATTR--AAKQAFAMAGRSP--SDVDVAEVHDFLTGIELMSYEDLGFAER
MMAR_0142|M.marinum_M               VNTLTRNAAKTAYEQAGVGP--SDLDLVELHDCFATAELVHYDNLMLCEQ
MUL_4955|M.ulcerans_Agy99           VNTLTRNAAKTAYEQAGVGP--SDLDLVELHDCFATAELVHYDNLMLCEQ
MAB_1864|M.abscessus_ATCC_1997      GANMNKAAIASVYAQAQIGP--DDLDVVELHDCFSANEILVYEALGFCEP
MLBr_01158|M.leprae_Br4923          QLGLTWLVEIGAHGVVAGPDSTLQSQPANAIKKAVDREGISVEQLDVVEI
                                                           : .  :  .     * :  : : .   

Mb0938c|M.bovis_AF2122/97           GESWKAIENGEIEIGGRLP--INPSGGLIGGGHPVGASGVRMLLDAAKQV
Rv0914c|M.tuberculosis_H37Rv        GESWKAIENGEIEIGGRLP--INPSGGLIGGGHPVGASGVRMLLDAAKQV
MSMEG_5608|M.smegmatis_MC2_155      GESWKAIENGEIEISGRLP--INPSGGLIGGGHPVGASGVRMLLDATKQV
TH_3699|M.thermoresistible__bu      GRAYKDVLSGEFDADGRLP--VNIDGGLKSFGHPVGASGLRMLYEAWLQF
MAV_5079|M.avium_104                GNAWKDVLSGEFDADGRLP--VNPDGGLKSFGHPVGASGLRMLYEAWLQF
Mflv_2505|M.gilvum_PYR-GCK          LGGYKLLEAEVTSVGGALP--VNPSGGLKAKGHPPGATGVAQCVELFAQL
Mvan_4153|M.vanbaalenii_PYR-1       LGGYKLLEAEVTSLGGALP--VNPSGGLKAKGHPPGATGVAQCVELFAQL
MMAR_0142|M.marinum_M               GGAADFFESGAPWRDGSTP--VNVSGGLQSKGHPIAATGIANVWEICHHL
MUL_4955|M.ulcerans_Agy99           GGAADFFESGAPWRHGSTP--VNVSGGLQSKGHPIAATGIANVWEICHQL
MAB_1864|M.abscessus_ATCC_1997      GAAGKLIDNQDTTFGGKWV--VNPSGGLISKGHPLGATGLAQCAELNWQL
MLBr_01158|M.leprae_Br4923          NEAFAAVALASARELGIAPELVNVNGGAIAVGHPLGMSGARITLHVALEL
                                      .   .        *     :* .**  . *** . :*     .   ..

Mb0938c|M.bovis_AF2122/97           SGIAGDYQVENAE----AFGTLNFGGSTATTVSFVVSTTRGS----
Rv0914c|M.tuberculosis_H37Rv        SGIAGDYQVENAE----AFGTLNFGGSTATTVSFVVSTTRGS----
MSMEG_5608|M.smegmatis_MC2_155      SASAGEYQVEAAK----TFGTLNFGGSTATTVSFVVTAGKE-----
TH_3699|M.thermoresistible__bu      RGAAGERQLAEPH----TALTHNLGGRPGGCVSFVSVVGRDR----
MAV_5079|M.avium_104                GGRAGARQLSDPH----TALTHNLGGRPGGCVSFVSIVSRTRRKRV
Mflv_2505|M.gilvum_PYR-GCK          RGEAVN-QVDGAR----IGLAHNIGG--PTAVAAVTILEGPDGG--
Mvan_4153|M.vanbaalenii_PYR-1       RGEAVN-QVDGAR----IGLAHNIGG--PTAVSAVTILEGPSGN--
MMAR_0142|M.marinum_M               RGEAGDRQIDNAK----VGLAHVIGLGSACGVHILERSAA------
MUL_4955|M.ulcerans_Agy99           RGEAGDRQIDNAK----VGLAHVIGLGSACGVHILERSAA------
MAB_1864|M.abscessus_ATCC_1997      RGKADKRQVAGAATKDGVALQHNIGLGGSVVVTAYRPANR------
MLBr_01158|M.leprae_Br4923          ARRGSGYGVAALC-----------GAGGQGDALILRAV--------
                                       .    :               *      .