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RRVAIVGAGMTPFGEHFALGMKDLLPMAFSECARTVDKGLSKADLQAAWFGAMGTADGFPSGILADTLGL PELPVTRVENSCATGHDAIRNALFGIASGAFDVALVMGADKLRDTTSAEMLWEWEAMARDMAWDYPLGLV APAGFALHVRRYLHESPATEEHLAMVAVKNHRHGVNNTKARLRFEITMEQALNAPTVVTPFRLYDCAPQS DGAAALVIAADDVVDRFTDRPVWITGVGLGLDSVMHQHKPDLTTFPATTRAAKQAFAMAGRSPSDVDVAE VHDFLTGIELMSYEDLGFAERLGGYKLLEAEVTSLGGALPVNPSGGLKAKGHPPGATGVAQCVELFAQLR GEAVNQVDGARIGLAHNIGGPTAVSAVTILEGPSGN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4153 | - | - | 100% (387) | thiolase family protein |
| M. vanbaalenii PYR-1 | Mvan_4694 | - | 1e-47 | 33.91% (404) | lipid-transfer protein |
| M. vanbaalenii PYR-1 | Mvan_2338 | - | 1e-47 | 33.42% (392) | lipid-transfer protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2813c | ltp1 | 3e-46 | 31.97% (391) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_2505 | - | 0.0 | 93.01% (386) | thiolase |
| M. tuberculosis H37Rv | Rv2790c | ltp1 | 3e-46 | 31.97% (391) | lipid-transfer protein |
| M. leprae Br4923 | MLBr_01158 | fadA4 | 5e-05 | 28.68% (129) | acetyl-CoA acetyltransferase |
| M. abscessus ATCC 19977 | MAB_0378 | - | 3e-48 | 34.62% (390) | lipid-transfer protein |
| M. marinum M | MMAR_1918 | ltp1 | 5e-46 | 32.65% (392) | lipid-transfer protein Ltp1 |
| M. avium 104 | MAV_2557 | - | 1e-168 | 72.97% (381) | thiolase family protein |
| M. smegmatis MC2 155 | MSMEG_3844 | - | 2e-45 | 35.99% (389) | lipid-transfer protein |
| M. thermoresistible (build 8) | TH_2717 | - | 0.0 | 85.68% (384) | PUTATIVE thiolase family protein |
| M. ulcerans Agy99 | MUL_2143 | ltp1 | 4e-46 | 32.65% (392) | lipid-transfer protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4153|M.vanbaalenii_PYR-1 ---------MRRVAIVGAGMTPFGEHFALGMKDLLPMAFS-ECARTVDKG
Mflv_2505|M.gilvum_PYR-GCK ---------MRRAAIVGAGMTPFAEHFALGIKDLIPMAFS-ACASSVDKG
TH_2717|M.thermoresistible__bu ---------MRKVAVVGAGMTAFREHFALGIKDLLPMAFA-ECAASVDKG
MAV_2557|M.avium_104 ---------MRKVAIVGAGMTPFAEHFELGIKDLVPMAYA-EAVANVDKG
MSMEG_3844|M.smegmatis_MC2_155 ------MSAPEPVYILGAGMHPWGK-WGRDFTEYGVVAAR-AALAEAGLD
MMAR_1918|M.marinum_M MPNNGS----NRVFVIGVGMTKFEKPGRREGWDYPDMARESGTNALNDAG
MUL_2143|M.ulcerans_Agy99 MPNNGS----NRVFVIGVGMTKFEKPGRREGWDYPDMARESGTNALNDAG
Mb2813c|M.bovis_AF2122/97 MPNQGSS---NKVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAG
Rv2790c|M.tuberculosis_H37Rv MPNQGSS---NKVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAG
MAB_0378|M.abscessus_ATCC_1997 MPPKGSSKVLEKVYVIGVGMTKFEKPGRREGWDYPAMAKESGTNALTDAG
MLBr_01158|M.leprae_Br4923 --------MTTSVIVTGARTPIGKLMGSLKDFSASDLGAITIAAALKKAN
. : *. . :. .
Mvan_4153|M.vanbaalenii_PYR-1 LSKADLQAAWFGAMGTADGFPSG-ILADTLGLPE-----LPVTRVENSCA
Mflv_2505|M.gilvum_PYR-GCK LAKDDLQAAWIGAMGTADGFPSG-ILADTLGLPN-----LPVTRVENSCA
TH_2717|M.thermoresistible__bu IAKADLQAAWFGCMGTADGFPSG-ILADSLGLPE-----LPVTRVENSCA
MAV_2557|M.avium_104 IQKSELEAAWFGELATTDGFPSG-ILADTLDLTD-----IPVTRVENACA
MSMEG_3844|M.smegmatis_MC2_155 WRQIQLVAGADTIRNGYPGFVAGATFAQKLGWNG-----VPVTSSYAACA
MMAR_1918|M.marinum_M IEYREVEHAYVGYVYGES--TSGQRAVYELGMTG-----IPVVNVNNNCS
MUL_2143|M.ulcerans_Agy99 IEYREVEHAYVGYVYGES--TSGQRAVYELGMTG-----IPVVNVNNNCS
Mb2813c|M.bovis_AF2122/97 IDYREVEQGYVGYVYGES--TSGQRALYELGMTG-----IPIVNVNNNCS
Rv2790c|M.tuberculosis_H37Rv IDYREVEQGYVGYVYGES--TSGQRALYELGMTG-----IPIVNVNNNCS
MAB_0378|M.abscessus_ATCC_1997 IDYGKVEAAYVGYCAGES--TSGQRAVYELGMTG-----IPVTNVNNNCS
MLBr_01158|M.leprae_Br4923 VAPSIVQYVIIGQVLTAG---AGQMPARQAAVAAGIGWDVPALTINKMCL
: :* :* *
Mvan_4153|M.vanbaalenii_PYR-1 TGHDAIRNALFGIASGAFDVALVMGADKLRDTTSAEMLWEWE-----AMA
Mflv_2505|M.gilvum_PYR-GCK TGHDAIRNALFGVSSGAFDVALVIGADKLRDTTSAGMLWEWE-----AMA
TH_2717|M.thermoresistible__bu TGNDAVRNAVFAVASGAYDVALVMGADKLRDTTSKDMLWEWE-----AMA
MAV_2557|M.avium_104 TGNDAIRNGTLAIASGLYDVVLVVGADKVRETSSNTTFWDWA-----AMT
MSMEG_3844|M.smegmatis_MC2_155 SGSQALQSARAQILAGFCDVALVVGADTTPKGFFAPVGGERK-----NDP
MMAR_1918|M.marinum_M TGSTALFLAAQAIRGGLADCTVALGFEKMKPGSLSSSYDDRTQPMDKHVK
MUL_2143|M.ulcerans_Agy99 TGSTALFLAAQAIRGGLADCTVALGFEKMKPGSLSSSYDDRTQPMDKHVK
Mb2813c|M.bovis_AF2122/97 TGSTALYLGAQAIRGGLADCVLALGFEKMQPGALGGGADDRESPLGRHVK
Rv2790c|M.tuberculosis_H37Rv TGSTALYLGAQAIRGGLADCVLALGFEKMQPGALGGGADDRESPLGRHVK
MAB_0378|M.abscessus_ATCC_1997 TGSTALYNAAQAIRGGLADVTLALGFEKMQPGSLGATFTDREQPMQRHIE
MLBr_01158|M.leprae_Br4923 SGLDAIALADQLIRAGEFDVVVAGGQESMTKAPHLLMDSRSG----YKYG
:* *: . : .* * .:. * :.
Mvan_4153|M.vanbaalenii_PYR-1 RDMAWDYPLGLVAPAGFALHVRRYLHESPATEEHLAMVAVKN-HRHGVNN
Mflv_2505|M.gilvum_PYR-GCK RDMAWDYPLGLVAPAGFALHVRRYLHESPATEEHLAMVAVKN-HRHGVNN
TH_2717|M.thermoresistible__bu RDMAWDYPLGLVSPAGFALHLRRYLHESPATREHLAMVAVKN-HRHGVSN
MAV_2557|M.avium_104 RDNAWDYPLGLVAPANFALHVMRYLHESPATKEHMAMVAVKN-HFHAVNN
MSMEG_3844|M.smegmatis_MC2_155 -DWQRFHLIGATNTVYFALLARRRMDLYGATLEDFAQVKVKN-ARHGLNN
MMAR_1918|M.marinum_M ALAQIAEFAFPVAPWMFGAAGREHMQQYGSTAEHFAKIGFKN-HKHSVNN
MUL_2143|M.ulcerans_Agy99 ALAQIAEFAFPVAPWMFGAAGREHMQQYGSTAEHFAKIGFKN-HKHSVNN
Mb2813c|M.bovis_AF2122/97 ALAEIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIGYKN-HKHSVNN
Rv2790c|M.tuberculosis_H37Rv ALAEIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIGYKN-HKHSVNN
MAB_0378|M.abscessus_ATCC_1997 ALAGVFDFAFPPAPWMFGAAGREHMQKYGTTAEHFAKIGYKN-HKHSVNN
MLBr_01158|M.leprae_Br4923 DVTIVDHLAYDGLHDVFTNQPMGALTEQRNDVEKFTRQEQDEFAARSHQK
* : *.:: .: :. .:
Mvan_4153|M.vanbaalenii_PYR-1 TKARLRFEITMEQALNAPTVVTPFRLYDCAPQSDGAAALVIAADDVVDR-
Mflv_2505|M.gilvum_PYR-GCK PKARLRFEITMEQALNAPTVVTPFRLYDCAPQSDGAAALVIASEDVVDK-
TH_2717|M.thermoresistible__bu PKARLRFEITLEQALSAPIVVTPFGLYDCAPQSDGAAALILAAEDVVDR-
MAV_2557|M.avium_104 PKAQLRYEITVEQALAAPIVVEPFGLYDCTPQSDGAAAVILAAEDVVDR-
MSMEG_3844|M.smegmatis_MC2_155 PNARYRKEASVEDVLASPVVSDPLRLLDICATSDGAAALVVASKSFVEK-
MMAR_1918|M.marinum_M PFAQFQEAYTLDDILASRMIYEPLTKLQCSPTSDGSGAAILASESFVDSH
MUL_2143|M.ulcerans_Agy99 PFAQFQEAYTLDDILASRMIYEPLTKLRCSPTSDGSGAAILASESFVDSH
Mb2813c|M.bovis_AF2122/97 PYAQFQDEYTLDDILASKMISDPLTKLQCSPTSDGSAAVVLASEDYLANH
Rv2790c|M.tuberculosis_H37Rv PYAQFQDEYTLDDILASKMISDPLTKLQCSPTSDGSAAVVLASEDYLANH
MAB_0378|M.abscessus_ATCC_1997 PYAQFQEEYTLQDILDAKEIYAPLTKLQCSPTSDGSGAAILASERFVEQN
MLBr_01158|M.leprae_Br4923 AAAAWKDGVFADEVVPVSIPQSKGDSLQFTEDEGIRANTSAESLAGLKPA
. * : :: : .. . : :
Mvan_4153|M.vanbaalenii_PYR-1 -FTDRPVWITGVGLG--LDSVMHQ-HKPDLTTFPATTRAAK---------
Mflv_2505|M.gilvum_PYR-GCK -FTDRPVWIRGVGLG--LDSVMHQ-HKPDLTTFPATTRAAK---------
TH_2717|M.thermoresistible__bu -FTNRPVWIRGVGLG--LDSVMHQ-HKTDMTTFPATVRAAR---------
MAV_2557|M.avium_104 -YTDRPVWVRGVGLG--MDRVMHQ-HKTDMTTFPPTVRAAK---------
MSMEG_3844|M.smegmatis_MC2_155 -HLGSVEGVPSVRAISLQSPQYPQ-HLPELPDIATDSTAVVKAPERVFKD
MMAR_1918|M.marinum_M GLAGRAVEIVGQAMTTDFASTFDG-SAKNLIGYDMNVQAAQ---------
MUL_2143|M.ulcerans_Agy99 GLAGRAVEIVGQAMTTDFASTFDG-SAKNLIGYDMNVQAAR---------
Mb2813c|M.bovis_AF2122/97 NLAGRAVEIVGQAMTTDFASTFDG-SARNIIGYDMTVQAAQ---------
Rv2790c|M.tuberculosis_H37Rv NLAGRAVEIVGQAMTTDFASTFDG-SARNIIGYDMTVQAAQ---------
MAB_0378|M.abscessus_ATCC_1997 GLGDRAVEIVGQAMTTDIPGTLESKSAITLVGFDMAKLAAQ---------
MLBr_01158|M.leprae_Br4923 FRCGGTITPGSASQISDGAATVVVMNKEKAQQLGLTWLVEIGAHG-----
. . .
Mvan_4153|M.vanbaalenii_PYR-1 ----QAFAMAGRSPSDVDVAEVHDFLTGIELMSYEDLGFAERLGGYKLLE
Mflv_2505|M.gilvum_PYR-GCK ----QAFAMAGMTPSDVDVAEVHDFLTGIELMSYEDLGFAEKLGGYKLLE
TH_2717|M.thermoresistible__bu ----QAFAMAGLTPADIDVAEVHDFFTGIELISYEDLGFVERFGAHKLVE
MAV_2557|M.avium_104 ----AAMAMAGVTPRDIDVAEVHDCFTGVELISYEDLGFAHRFEAYKLVE
MSMEG_3844|M.smegmatis_MC2_155 QILDAAYAEAGIGPEDLSLAEVYDLSTALELDWYEHLGLCEKGEAEQLLR
MMAR_1918|M.marinum_M ----RVYQQSGLGPEDFQVIELHDCFSANELLLYEALGLCGQGEAPKLID
MUL_2143|M.ulcerans_Agy99 ----RVYQQSGLGPEDFQVIELHDCFSANELLLYEALGLCGQGEAPKLID
Mb2813c|M.bovis_AF2122/97 ----RVYQQSGLGPKDFGVIELHDCFSANELLLYEALGLCGPGEAPELID
Rv2790c|M.tuberculosis_H37Rv ----RVYQQSGLGPKDFGVIELHDCFSANELLLYEALGLCGPGEAPELID
MAB_0378|M.abscessus_ATCC_1997 ----KVYEQAQISADDVDVIELHDCFSANELITYEALGLCAEGEGGKLVD
MLBr_01158|M.leprae_Br4923 ---VVAGPDSTLQSQPANAIKKAVDREGISVEQLDVVEINEAFAAVALAS
. : . : . .: : : : . *
Mvan_4153|M.vanbaalenii_PYR-1 AEVTSLGGALPVNPSGGLKAKGHPPGATGVAQCVELFAQLRGEAVN-QVD
Mflv_2505|M.gilvum_PYR-GCK AEVTSVGGALPVNPSGGLKAKGHPPGATGVAQCVELFAQLRGEAVN-QVD
TH_2717|M.thermoresistible__bu AEVTSVGGSLPVNPSGGLKAKGHPPGATGVAQCVELFGQLRGEAAN-QVD
MAV_2557|M.avium_104 GREHYVGGSIPINPSGGLKAKGHPPGATGVAQCYELFNQLRGEAEN-QVD
MSMEG_3844|M.smegmatis_MC2_155 SGATTIGGRIPVNASGGLACFGEAIPAQAIAQVCELTWQLKGQATGRQVE
MMAR_1918|M.marinum_M NGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCCELTWQLRGTADRRQVD
MUL_2143|M.ulcerans_Agy99 NGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCCELTWQLRGTADRRQVD
Mb2813c|M.bovis_AF2122/97 DNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGTAEARQVD
Rv2790c|M.tuberculosis_H37Rv DNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGTAEARQVD
MAB_0378|M.abscessus_ATCC_1997 NGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGDADKRQVA
MLBr_01158|M.leprae_Br4923 ARELGIAP-ELVNVNGGAIAVGHPLGMSGARITLHVALELARRGSG----
. :* .** . *.. . .: :* .
Mvan_4153|M.vanbaalenii_PYR-1 GAR----IGLAHNIGGPTAVSAVTILEGP--SGN
Mflv_2505|M.gilvum_PYR-GCK GAR----IGLAHNIGGPTAVAAVTILEGP--DGG
TH_2717|M.thermoresistible__bu GAR----IGLAHNIGGPTAVAAVTILEGPGTDGD
MAV_2557|M.avium_104 GAR----IALAHNIGGPTAVSAVTVLSNQ---KN
MSMEG_3844|M.smegmatis_MC2_155 GAK----VGITANQGLFGHGSSVIVAR-------
MMAR_1918|M.marinum_M DVT----AALQHNIGLGGAAVVTAYQRAER----
MUL_2143|M.ulcerans_Agy99 NVT----AALQHNIGLGGAAVVTAYQRAER----
Mb2813c|M.bovis_AF2122/97 NVT----AALQHNIGLGGAAVVTAYQRAER----
Rv2790c|M.tuberculosis_H37Rv NVT----AALQHNIGLGGAAVVTAYQRAER----
MAB_0378|M.abscessus_ATCC_1997 SASQKTGVALQHNLGLGGACVVTAYKPANR----
MLBr_01158|M.leprae_Br4923 -------YGVAALCGAGGQGDALILRAV------
.: *