For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MDDGVWILGGYQSDFARNLSKENRDFADLTREVVDGTLTAAKVDAADLAAAGVVHVANAFGEMFARQGHL GAMPATVCDDLWDTPATRHEAACASGSVATLAAMADLRSGAYRVALVVGLELEKTVPGDTAAEHLSAAAW TGHEGAEARYLWPSMFAQVADEYDRRYGLDDTHLRAIAQLNFANARRNPNAQTRGWTIPDPITDDDATNP LTEGRLRRFDCSQMTDGGAGLVLVSDAYLRDHRDARPIGRIDGWGHRTVGLGLRQKLDRVAQGDSAPYLL PHVRATVLDALRRARVTLDDLDGIEVHDCFTPSEYLAIDHIGLTGPGESWKAIENGEIEIGGRLPINPSG GLIGGGHPVGASGVRMLLDAAKQVSGIAGDYQVENAEAFGTLNFGGSTATTVSFVVSTTRGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0938c | - | - | 100% (412) | acetyl-CoA acetyltransferase |
| M. bovis AF2122 / 97 | Mb2813c | ltp1 | 3e-32 | 28.09% (413) | lipid-transfer protein |
| M. bovis AF2122 / 97 | Mb3553 | - | 1e-21 | 30.17% (401) | acetyl-CoA acetyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1808 | - | 0.0 | 76.66% (407) | acetyl-CoA acetyltransferase |
| M. tuberculosis H37Rv | Rv0914c | - | 0.0 | 100.00% (412) | acetyl-CoA acetyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0378 | - | 3e-32 | 27.68% (401) | lipid-transfer protein |
| M. marinum M | MMAR_4613 | - | 0.0 | 87.47% (407) | lipid carrier protein or keto acyl-CoA thiolase |
| M. avium 104 | MAV_5079 | - | 3e-40 | 34.76% (351) | acetyl-CoA acetyltransferase |
| M. smegmatis MC2 155 | MSMEG_5608 | - | 0.0 | 78.27% (405) | acetyl-CoA acetyltransferase |
| M. thermoresistible (build 8) | TH_3699 | - | 9e-40 | 34.40% (343) | PUTATIVE thiolase |
| M. ulcerans Agy99 | MUL_2143 | ltp1 | 1e-30 | 27.78% (414) | lipid-transfer protein |
| M. vanbaalenii PYR-1 | Mvan_4939 | - | 1e-180 | 76.35% (406) | acetyl-CoA acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1808|M.gilvum_PYR-GCK ------MRSADDVWILGGYQSDFACNYHRDGRGFSELTAEVVESTLRDAC
Mvan_4939|M.vanbaalenii_PYR-1 -------MSSTGVWILGGYQSDFARNYDREGLDFAGLTAEVVEATLEASG
Mb0938c|M.bovis_AF2122/97 ------MD--DGVWILGGYQSDFARNLSKENRDFADLTREVVDGTLTAAK
Rv0914c|M.tuberculosis_H37Rv ------MD--DGVWILGGYQSDFARNLSKENRDFADLTREVVDGTLTAAK
MMAR_4613|M.marinum_M ------MDGTTGVWILGGYQSDFARNLTKENRDFADLTAEVVPGTLAAAQ
MSMEG_5608|M.smegmatis_MC2_155 ------MEN---VWVLGGYQSDFARNLTRENLDFADLTREVVENTLAHAK
MAV_5079|M.avium_104 --------------MPSNGIAGKVAVVAMGCSHFGERWDASTEDLILEAY
TH_3699|M.thermoresistible__bu --------------MASNGIAGKVAVVGMGCTRFGERWDASADDLILEAY
MAB_0378|M.abscessus_ATCC_1997 MPPKGSSKVLEKVYVIGVGMTKFEKPGRREGWDYPAMAKESGTNALTDAG
MUL_2143|M.ulcerans_Agy99 MPNNGSN----RVFVIGVGMTKFEKPGRREGWDYPDMARESGTNALNDAG
: . : : : :
Mflv_1808|M.gilvum_PYR-GCK VDARDIG---VVHVANAFGELFAHQGHLGAMPATVVDGLWDTPATRHEAA
Mvan_4939|M.vanbaalenii_PYR-1 VDAADIG---VVHVANAFGGLFARQGHLGAMPATVNDGLWGTPAVRHEAA
Mb0938c|M.bovis_AF2122/97 VDAADLAAAGVVHVANAFGEMFARQGHLGAMPATVCDDLWDTPATRHEAA
Rv0914c|M.tuberculosis_H37Rv VDAADLAAAGVVHVANAFGEMFARQGHLGAMPATVCDDLWDTPATRHEAA
MMAR_4613|M.marinum_M IEAADIG---VVHVANAFGEMFAGQGHLGAMPATVSDGLWDTPASRHEAA
MSMEG_5608|M.smegmatis_MC2_155 IDASDIG---VVHVANAFGELFARQGHLGAMPATVHEGLWDTPSSRHEAA
MAV_5079|M.avium_104 QECLDSVPNLGADDVDAFWLGTLSSG-LGGLTLSRAIGNDDKPVTRVENF
TH_3699|M.thermoresistible__bu AEALDSAG-ISRDDIDAYWLGTLSSG-LGGLTLSRAIGSDDKPVTRVENF
MAB_0378|M.abscessus_ATCC_1997 IDY---------GKVEAAYVGYCAGESTSGQRAVYELGMTGIPVTNVNNN
MUL_2143|M.ulcerans_Agy99 IEY---------REVEHAYVGYVYGESTSGQRAVYELGMTGIPVVNVNNN
: : .. . . * . :
Mflv_1808|M.gilvum_PYR-GCK CASGSVAALAAIADLRSGAYRTALVVGVELEKTVPGDTATSILGAAAWTG
Mvan_4939|M.vanbaalenii_PYR-1 CASGSVAALAAIADLRSGAYTSALVVGVELEKTVPGDEATSILGSAAWTG
Mb0938c|M.bovis_AF2122/97 CASGSVATLAAMADLRSGAYRVALVVGLELEKTVPGDTAAEHLSAAAWTG
Rv0914c|M.tuberculosis_H37Rv CASGSVATLAAMADLRSGAYRVALVVGLELEKTVPGDTAAEHLSAAAWTG
MMAR_4613|M.marinum_M CASGSVATLAAIADLRSGFYNSALVVGLELEKTVPGDTAAQYLGAAGWTG
MSMEG_5608|M.smegmatis_MC2_155 CASGSVAALAAIADLRSGAYDTALVVGVELEKTVPGDDAAANLGTAAWTG
MAV_5079|M.avium_104 CATGSEAFRNACYAVAAGAYDVAMALGVEKLKDS---GYSGLLRQDPPGD
TH_3699|M.thermoresistible__bu CATGSEAFRNACYAVASGAYDIAMAVGVEKLKDS---GYSGLLRQDPPGD
MAB_0378|M.abscessus_ATCC_1997 CSTGSTALYNAAQAIRGGLADVTLALGFEKMQPGSLGATFTDREQPMQRH
MUL_2143|M.ulcerans_Agy99 CSTGSTALFLAAQAIRGGLADCTVALGFEKMKPGSLSSSYDDRTQPMDKH
*::** * * : .* ::.:*.* :
Mflv_1808|M.gilvum_PYR-GCK HEGRD-----AKFMWPHMFNAVADEYDRRYGLDESHLRAIADLNFTNARA
Mvan_4939|M.vanbaalenii_PYR-1 HEGQQ-----AKYMWPYMFETVAAEYDRRYGLDESHLHAIASLNFANAKT
Mb0938c|M.bovis_AF2122/97 HEGAE-----ARYLWPSMFAQVADEYDRRYGLDDTHLRAIAQLNFANARR
Rv0914c|M.tuberculosis_H37Rv HEGAE-----ARYLWPSMFAQVADEYDRRYGLDDTHLRAIAQLNFANARR
MMAR_4613|M.marinum_M HEGAE-----ARYLWPSVFTQVADEYDRRYGLDDTHLHSIAQLNYANARR
MSMEG_5608|M.smegmatis_MC2_155 HEGAD-----ATYMWPWMFSKVADEYDRRYCLDPAHLRVIAAVNFANARR
MAV_5079|M.avium_104 GTAPE-----LSMTAPAAFSMLDPAYCARHGVHPDEMRAAMTHVAWKNHD
TH_3699|M.thermoresistible__bu GTAPE-----ISMTAPAAFSMLDPAYCARYGVHPDEMRAAMTHVAWKNHD
MAB_0378|M.abscessus_ATCC_1997 IEALAGVFDFAFPPAPWMFGAAGREHMQKYGTTAEHFAKIG----YKNHK
MUL_2143|M.ulcerans_Agy99 VKALAQIAEFAFPVAPWMFGAAGREHMQQYGSTAEHFAKIG----FKNHK
. * * : :: .: : :
Mflv_1808|M.gilvum_PYR-GCK NPLAQTRDWSVPSPPTADDTSNPVVDGRLRRLDCSQLTDGGAGLVLVSDA
Mvan_4939|M.vanbaalenii_PYR-1 NPRAQTRTWAVPERVSADDTQNPVIEGRLRRLDCSQLTDGGAGVVLVSDD
Mb0938c|M.bovis_AF2122/97 NPNAQTRGWTIPDPITDDDATNPLTEGRLRRFDCSQMTDGGAGLVLVSDA
Rv0914c|M.tuberculosis_H37Rv NPNAQTRGWTIPDPITDDDATNPLTEGRLRRFDCSQMTDGGAGLVLVSDA
MMAR_4613|M.marinum_M NPNAQTRGWTIPDPITDDDATNPITEGRLRRLDCSQMTDGGAGLVLVNDA
MSMEG_5608|M.smegmatis_MC2_155 NPNAQTRTWNVPDPLTDDDATNPVVEGRIRRFDCSQMTDGGAGVVLVTDR
MAV_5079|M.avium_104 NGTRNPKAQFRSPVSRDTIDNAPKVAGRLGVFDCSGISDGAACALIVPAE
TH_3699|M.thermoresistible__bu NGSRNPKAQFRSGVSKETIDKAVKVAGRLGVFDCSGVSDGAACAVIVPAD
MAB_0378|M.abscessus_ATCC_1997 HSVNNPYAQFQEEYTLQDILDAKEIYAPLTKLQCSPTSDGSGAAILASER
MUL_2143|M.ulcerans_Agy99 HSVNNPFAQFQEAYTLDDILASRMIYEPLTKLRCSPTSDGSGAAILASES
: :. : : ** :**.. ::.
Mflv_1808|M.gilvum_PYR-GCK WLRDNPAARPLGRIDGWGHRTVGLGLRQKLDH---SAGNPYVFPHVRSAV
Mvan_4939|M.vanbaalenii_PYR-1 WLRDHPTARPLGRIDGWGHRTVGLGLQQKLDH---SAGDPYVFPHVRAAV
Mb0938c|M.bovis_AF2122/97 YLRDHRDARPIGRIDGWGHRTVGLGLRQKLDRVAQGDSAPYLLPHVRATV
Rv0914c|M.tuberculosis_H37Rv YLRDHRDARPIGRIDGWGHRTVGLGLRQKLDRVAQGDSAPYLLPHVRATV
MMAR_4613|M.marinum_M YLRDHPGARPIGRIDGWGHCTVGLGLQQKLDRPAQGESGQYVLPHVRKAA
MSMEG_5608|M.smegmatis_MC2_155 WLRAHPGVTPQARIAGWGHRTVGLGLQQKIDR---ADADPYLLPHVRGAV
MAV_5079|M.avium_104 RAREYTDTPMYVEALSLIAGSARASMDPGYDFT--------TFPEVVKSA
TH_3699|M.thermoresistible__bu RAHEYTDTPMYVRALSLVSGSARGAVDAGYDYT--------TFPEVVRSA
MAB_0378|M.abscessus_ATCC_1997 FVEQNGLGDRAVEIVGQAMTTDIPGTLESKSAITLVG-----FDMAKLAA
MUL_2143|M.ulcerans_Agy99 FVDSHGLAGRAVEIVGQAMTTDFASTFDG-SAKNLIG-----YDMNVQAA
. . : . . :.
Mflv_1808|M.gilvum_PYR-GCK QDAFGRARVT--LDEVDGFEVHDCFTPSEYLAIDHIGLTEPGQSWKAIEH
Mvan_4939|M.vanbaalenii_PYR-1 LDAFGRAEVT--LDDVDGFEVHDCFTPSEYLAIDHIGLTAPGESWKAIEH
Mb0938c|M.bovis_AF2122/97 LDALRRARVT--LDDLDGIEVHDCFTPSEYLAIDHIGLTGPGESWKAIEN
Rv0914c|M.tuberculosis_H37Rv LDALRRARVT--LDDLDGIEVHDCFTPSEYLAIDHIGLTGPGESWKAIEN
MMAR_4613|M.marinum_M LDALRRAHVS--LDDLNGYEVHDCFTPSEYLAIDHIGLTGPGESWKAIEN
MSMEG_5608|M.smegmatis_MC2_155 QDAFGRAQVT--LDDIDGFEVHDCFTPSEYLAIDHIGLTGPGESWKAIEN
MAV_5079|M.avium_104 KDAYTQAGIEHPARELSLAEVHDCFTPTEIVLMEDLGFSVAGNAWKDVLS
TH_3699|M.thermoresistible__bu RDAYAQAGIDDPATQLSFAEVHDCFTPTEIVLMEDLGFTEPGRAYKDVLS
MAB_0378|M.abscessus_ATCC_1997 QKVYEQAQIS--ADDVDVIELHDCFSANELITYEALGLCAEGEGGKLVDN
MUL_2143|M.ulcerans_Agy99 RRVYQQSGLG--PEDFQVIELHDCFSANELLLYEALGLCGQGEAPKLIDN
. :: : :.. *:****:..* : : :*: *.. * :
Mflv_1808|M.gilvum_PYR-GCK GEIAIGGRLPVNPSGGLIGGGHPVGASGVRMLLDAARQVSDTAGDYQVEG
Mvan_4939|M.vanbaalenii_PYR-1 GEIALGGTLPINPSGGLIGGGHPVGASGVRMLLDAARQVSDTAGDYQVDG
Mb0938c|M.bovis_AF2122/97 GEIEIGGRLPINPSGGLIGGGHPVGASGVRMLLDAAKQVSGIAGDYQVEN
Rv0914c|M.tuberculosis_H37Rv GEIEIGGRLPINPSGGLIGGGHPVGASGVRMLLDAAKQVSGIAGDYQVEN
MMAR_4613|M.marinum_M GEIEIGGRLPINPSGGLIGGGHPVGASGVRMLLDAAKQVSGAAGDYQVEN
MSMEG_5608|M.smegmatis_MC2_155 GEIEISGRLPINPSGGLIGGGHPVGASGVRMLLDATKQVSASAGEYQVEA
MAV_5079|M.avium_104 GEFDADGRLPVNPDGGLKSFGHPVGASGLRMLYEAWLQFGGRAGARQLSD
TH_3699|M.thermoresistible__bu GEFDADGRLPVNIDGGLKSFGHPVGASGLRMLYEAWLQFRGAAGERQLAE
MAB_0378|M.abscessus_ATCC_1997 GDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGDADKRQVAS
MUL_2143|M.ulcerans_Agy99 GDTTYGGRWVVNPSGGLISKGHPLGATGLAQCCELTWQLRGTADRRQVDN
*: .* :* .*** . ***:**:*: : *. *. *:
Mflv_1808|M.gilvum_PYR-GCK AKTFGTLNFGGSTATTVSFVVGSTP------
Mvan_4939|M.vanbaalenii_PYR-1 AKTFGTLNFGGSTATTVSFVVGRTP------
Mb0938c|M.bovis_AF2122/97 AEAFGTLNFGGSTATTVSFVVSTTRGS----
Rv0914c|M.tuberculosis_H37Rv AEAFGTLNFGGSTATTVSFVVSTTRGS----
MMAR_4613|M.marinum_M ATKFGTLNFGGSTATTVSFVVSTTKDA----
MSMEG_5608|M.smegmatis_MC2_155 AKTFGTLNFGGSTATTVSFVVTAGKE-----
MAV_5079|M.avium_104 PHTALTHNLGGRPGGCVSFVSIVSRTRRKRV
TH_3699|M.thermoresistible__bu PHTALTHNLGGRPGGCVSFVSVVGRDR----
MAB_0378|M.abscessus_ATCC_1997 ASQKTGVALQHNLGLGGACVVTAYKPANR--
MUL_2143|M.ulcerans_Agy99 VT----AALQHNIGLGGAAVVTAYQRAER--
: . : *