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MSASDEIWILGIRMTKFGKHPDLDTVDLAAQAAMSALDDAGVSMADIGVLAAGNLMAANAGIGQQLQKQI GQTGIPVYNVANACATGATALRTAIMAVKAGEVDYGMAVGVEKLSGAGLLGGGGKKKSDADVWTPAGRYG AVAPVDGRIGTETMPGVFAQIGTEYGHKYGGTSFELFAKISEKNHAHSTLNPLAAYQKRFTLEQIMNDVM IAYPNTRPMCSANCDGAAAAIVCNGETLKSLSARQRRRAVKVSASVLTTDPYEPGCQVLPNVNTLTRNAA KTAYEQAGVGPSDLDLVELHDCFATAELVHYDNLMLCEQGGAADFFESGAPWRHGSTPVNVSGGLQSKGH PIAATGIANVWEICHQLRGEAGDRQIDNAKVGLAHVIGLGSACGVHILERSAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4955 | ltp1_1 | - | 100% (403) | lipid-transfer protein Ltp1_1 |
| M. ulcerans Agy99 | MUL_2143 | ltp1 | 1e-63 | 36.21% (406) | lipid-transfer protein |
| M. ulcerans Agy99 | MUL_4101 | ltp2_1 | 9e-24 | 28.76% (379) | lipid-transfer protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2813c | ltp1 | 4e-66 | 37.53% (405) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_2025 | - | 8e-62 | 35.57% (402) | lipid-transfer protein |
| M. tuberculosis H37Rv | Rv2790c | ltp1 | 4e-66 | 37.53% (405) | lipid-transfer protein |
| M. leprae Br4923 | MLBr_02162 | fadA | 2e-09 | 24.27% (375) | acetyl-CoA acetyltransferase |
| M. abscessus ATCC 19977 | MAB_0378 | - | 2e-59 | 36.23% (403) | lipid-transfer protein |
| M. marinum M | MMAR_0142 | ltp1_1 | 0.0 | 99.50% (403) | lipid-transfer protein Ltp1_1 |
| M. avium 104 | MAV_3681 | - | 6e-65 | 37.28% (405) | lipid-transfer protein |
| M. smegmatis MC2 155 | MSMEG_2236 | - | 3e-47 | 32.52% (409) | putative thiolase |
| M. thermoresistible (build 8) | TH_0532 | - | 6e-49 | 32.43% (404) | putative thiolase |
| M. vanbaalenii PYR-1 | Mvan_2338 | - | 8e-63 | 36.23% (403) | lipid-transfer protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4955|M.ulcerans_Agy99 ------MSASDEIWILGIRMTKFG---KHPDLDTVDLAAQAAMSALDDAG
MMAR_0142|M.marinum_M ------MSASDEIWILGIRMTKFG---KHPDLDTVDLAAQAAMSALDDAG
MSMEG_2236|M.smegmatis_MC2_155 ------MSHD--VAIIGVGIHPFG---RFEGKTAMQMGVDAIFAAVADAG
TH_0532|M.thermoresistible__bu ------MSNENSVAIIGVGLHPFG---RFD-KTAMEMGAEAIAAALADAG
Mb2813c|M.bovis_AF2122/97 MPNQGSS---NKVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAG
Rv2790c|M.tuberculosis_H37Rv MPNQGSS---NKVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAG
Mflv_2025|M.gilvum_PYR-GCK ------M---NRVFVVGVGMTKFEKPGRMENWDYPDMARESGTKALEDAG
MAV_3681|M.avium_104 -----MS---NKVYVVGVGMTKFEKPGRREGWDYPGMARESGTNALADAG
Mvan_2338|M.vanbaalenii_PYR-1 -----MP---NKVFVIGVGMTKFEKPGSREGWDYPDMAREAGTKALDDAG
MAB_0378|M.abscessus_ATCC_1997 MPPKGSSKVLEKVYVIGVGMTKFEKPGRREGWDYPAMAKESGTNALTDAG
MLBr_02162|M.leprae_Br4923 -----MSEEAFIYEAIRTPRGKQKNGSLHEVKPVSLVVGLVEELRKRNPD
: : :..
MUL_4955|M.ulcerans_Agy99 VSMADIGVLAAGNLMAANAGIGQQLQKQIGQTGIPVYN----VANACATG
MMAR_0142|M.marinum_M VSMADIGVLAAGNLMAANAGIGQQLQKQIGQTGIPVYN----VANACATG
MSMEG_2236|M.smegmatis_MC2_155 VDWKDIGAATGGSWTVANP---DAIVGMVGLSGIPFTN----VFNACATA
TH_0532|M.thermoresistible__bu LEWKDIQFGYGGSYEISNP---DAVTRLVGLTGITFTN----VFNACATA
Mb2813c|M.bovis_AF2122/97 IDYREVEQGYVG-YVYGESTSGQRALYELGMTGIPIVN----VNNNCSTG
Rv2790c|M.tuberculosis_H37Rv IDYREVEQGYVG-YVYGESTSGQRALYELGMTGIPIVN----VNNNCSTG
Mflv_2025|M.gilvum_PYR-GCK IAYSEIQQGYVG-YCSGDSTSGQRALYELGMTGIPIVN----VNNNCSTG
MAV_3681|M.avium_104 IDYREVQQGYVG-YVAGDSTSGQRALYELGMTGIPIVN----VNNNCSTG
Mvan_2338|M.vanbaalenii_PYR-1 VDYREVEEAYVG-YVYGESTSGQRAVYELGMTGVPVVN----VNNNCSTG
MAB_0378|M.abscessus_ATCC_1997 IDYGKVEAAYVG-YCAGESTSGQRAVYELGMTGIPVTN----VNNNCSTG
MLBr_02162|M.leprae_Br4923 LDENLISDVILGCVSPVGDQGGDIARATVLAAGLPVTAGGVQLNRFCASG
: : * : : :*:.. : . *::.
MUL_4955|M.ulcerans_Agy99 ATALRTAIMAVKAGEVDYGMAVGVEKLSGAGLLGGGGKK-----------
MMAR_0142|M.marinum_M ATALRTAIMAVKAGEVDYGMAVGVEKLSGAGLLGGGGKK-----------
MSMEG_2236|M.smegmatis_MC2_155 ASATKVCADGIRLGDYDIGIAVGLDKHPRG--------------------
TH_0532|M.thermoresistible__bu ASAIQETADTIRLGKYDIGIAIGMDKHPRG--------------------
Mb2813c|M.bovis_AF2122/97 STALYLGAQAIRGGLADCVLALGFEKMQPGALGGG---------------
Rv2790c|M.tuberculosis_H37Rv STALYLGAQAIRGGLADCVLALGFEKMQPGALGGG---------------
Mflv_2025|M.gilvum_PYR-GCK STALYLAAQSIRGGLADCVLALGFEKMQPGSLGGG---------------
MAV_3681|M.avium_104 STALFLAAQAIRGGLVDCAIALGFEKMQPGSLGGG---------------
Mvan_2338|M.vanbaalenii_PYR-1 STALYLAARAVRGGLADCTLALGFEKMQPGSLGST---------------
MAB_0378|M.abscessus_ATCC_1997 STALYNAAQAIRGGLADVTLALGFEKMQPGSLGAT---------------
MLBr_02162|M.leprae_Br4923 LEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSDGGAMGLDPATNYDVM
* :: * * :* *.:.
MUL_4955|M.ulcerans_Agy99 ----------KSDADVWTPAGRYGAVAPVDGRIGTETMPGVFAQIGTEYG
MMAR_0142|M.marinum_M ----------KSDADVWTPAGRYGAVAPVDGRIGTETMPGVFAQIGTEYG
MSMEG_2236|M.smegmatis_MC2_155 ---------------AFTEDPALVGMPKWYAENGQYLTTQFFGMKANRYL
TH_0532|M.thermoresistible__bu ---------------AFTDDPAKLALPQWYAQNGQFVTTKFFGMKANRYL
Mb2813c|M.bovis_AF2122/97 ------------ADDRESPLGRHVKALAEIDEFGFPVAPWMFGAAGREHM
Rv2790c|M.tuberculosis_H37Rv ------------ADDRESPLGRHVKALAEIDEFGFPVAPWMFGAAGREHM
Mflv_2025|M.gilvum_PYR-GCK ------------AQDRESPLGRHVKALSEIDEFAFPVAPWMFGAAGREHM
MAV_3681|M.avium_104 ------------AQDRESPMGRHVKAMAEIDEFAMPVAPWMFGAAGREHM
Mvan_2338|M.vanbaalenii_PYR-1 ------------YDDRAQPMEKHFLALAEISEVLFPPAPWMFGAAGREHM
MAB_0378|M.abscessus_ATCC_1997 ------------FTDREQPMQRHIEALAGVFDFAFPPAPWMFGAAGREHM
MLBr_02162|M.leprae_Br4923 FVPQGIGADLIATIEGFSRDDVDVYALRSQEKAAAAWSGGYFAKSVVPVR
*.
MUL_4955|M.ulcerans_Agy99 HKYGGTSFELFAKISEKNHAHSTLNPLAAYQKRFTLEQIMNDVMIAYPNT
MMAR_0142|M.marinum_M HKYGGTSFELFAKISEKNHAHSTLNPLAAYQKRFTLEQIMNDVMIAYPNT
MSMEG_2236|M.smegmatis_MC2_155 HDHN-ISRRTLARVAAKNFRNGALNPNAFRRKPISEDDILNSTMLNYPLT
TH_0532|M.thermoresistible__bu HDHG-ISQETLARVANKNFRNGSLNPNAFRRKEISVEDILNSPVLNYPLT
Mb2813c|M.bovis_AF2122/97 KKYG-TTAEHFAKIGYKNHKHSVNNPYAQFQDEYTLDDILASKMISDPLT
Rv2790c|M.tuberculosis_H37Rv KKYG-TTAEHFAKIGYKNHKHSVNNPYAQFQDEYTLDDILASKMISDPLT
Mflv_2025|M.gilvum_PYR-GCK KKYG-TTAEHFAKIGFKNHKHSVNNPYAQFQDEYSLDDILAAKMISDPLT
MAV_3681|M.avium_104 RQYG-STAEHFAKIGYKNHKHSVNNPFAQFQESYTLEDILAARMISDPLT
Mvan_2338|M.vanbaalenii_PYR-1 KEYG-STAEHFAKIGYKNHKHSVNNPYAQFQDEYTLDDILDSRMIYDPLT
MAB_0378|M.abscessus_ATCC_1997 QKYG-TTAEHFAKIGYKNHKHSVNNPYAQFQEEYTLQDILDAKEIYAPLT
MLBr_02162|M.leprae_Br4923 DQNGLLILDHDEHMRPDTSKEGLAKLKPAFEGLAAMGGFDDVALQKYHWV
. . :: .. .. : . . : : .
MUL_4955|M.ulcerans_Agy99 RPMCSANCDGAAAAIVCNGETLKSLSAR-QRRRAVKVSASVLTTDPYEPG
MMAR_0142|M.marinum_M RPMCSANCDGAAAAIVCNGETLKSLSAR-QRRRAVKVSASVLTTDPYEPG
MSMEG_2236|M.smegmatis_MC2_155 QYMFCAPDEGAAAVVMCRADIAHRYTDKPVYLKAVEVRTRRYGAYEVNTT
TH_0532|M.thermoresistible__bu QYMFCAPDEGAAAVIMCRGDIAHRFTDKPVYVRASEIRTRRYGAYEVHAT
Mb2813c|M.bovis_AF2122/97 KLQCSPTSDGSAAVVLASEDYLANHNLAGRAVEIVGQAMTTDFASTFDG-
Rv2790c|M.tuberculosis_H37Rv KLQCSPTSDGSAAVVLASEDYLANHNLAGRAVEIVGQAMTTDFASTFDG-
Mflv_2025|M.gilvum_PYR-GCK KLQCSPTSDGSAAVVLASEDYVARHDLAGQAVEIVGQAMTTDFASTFDG-
MAV_3681|M.avium_104 KLQCSPTSDGSGAAILASEAFVDKHGLAGQAVEIVGQAMTTDFASTFDG-
Mvan_2338|M.vanbaalenii_PYR-1 KLQCSPTSDGSGAAILASEDFVDRHGLADRAVEIVGQAMTSDFSDSFDG-
MAB_0378|M.abscessus_ATCC_1997 KLQCSPTSDGSGAAILASERFVEQNGLGDRAVEIVGQAMTTDIPGTLESK
MLBr_02162|M.leprae_Br4923 EKINHVHTGGNSSGIVDGAALVMIGSEAVGKSQGLTPRARMVATATSGAD
. * .: :: . .
MUL_4955|M.ulcerans_Agy99 CQVLPNVNTLTRNAAKTAYEQAGVGPSDLDLVELHDCFATAELVHYDNLM
MMAR_0142|M.marinum_M CQVLPNVNTLTRNAAKTAYEQAGVGPSDLDLVELHDCFATAELVHYDNLM
MSMEG_2236|M.smegmatis_MC2_155 CAPVEEDVAPTVYAARAAFEKAGVAPEDVDVIQLQDTDAGAEIIHMAECG
TH_0532|M.thermoresistible__bu SAPLEEDVAPTVYAARAAYEAAGIGPEDVDIAQLQDTDAGAEVIHMAETG
Mb2813c|M.bovis_AF2122/97 SARNIIGYDMTVQAAQRVYQQSGLGPKDFGVIELHDCFSANELLLYEALG
Rv2790c|M.tuberculosis_H37Rv SARNIIGYDMTVQAAQRVYQQSGLGPKDFGVIELHDCFSANELLLYEALG
Mflv_2025|M.gilvum_PYR-GCK SAANIIGHDMNVKAAQQVYSQSGLGPEDFQVIELHDCFSANELLLYEALG
MAV_3681|M.avium_104 SAKNLIGYDMNVQAAQQVYDQSGLGPQDFQVIELHDCFSANELLLYEALG
Mvan_2338|M.vanbaalenii_PYR-1 TCKALIGYHMNVAAAQSVYEQAGLGPEEFQVIELHDCFSANELLLYEALG
MAB_0378|M.abscessus_ATCC_1997 SAITLVGFDMAKLAAQKVYEQAQISADDVDVIELHDCFSANELITYEALG
MLBr_02162|M.leprae_Br4923 PVIMLTGPTP---ATRKVLDRAGLTVDDIDLFELNEAFASVVLKFQKDLN
*:: . . : : .:. : :*:: : :
MUL_4955|M.ulcerans_Agy99 LCEQGGAADFFESGAPWRHGSTPVNVSGGLQSKGHPIAATGIANVWEICH
MMAR_0142|M.marinum_M LCEQGGAADFFESGAPWRDGSTPVNVSGGLQSKGHPIAATGIANVWEICH
MSMEG_2236|M.smegmatis_MC2_155 FCAHGDQEKLLADGATEIGGSLPVNTDGGLIANGEPIGASGLRQIHELVR
TH_0532|M.thermoresistible__bu LCADGEQEKLLAEGATEINGSLPINTDGGLIANGEPIGASGLRQIHELVR
Mb2813c|M.bovis_AF2122/97 LCGPGEAPELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTW
Rv2790c|M.tuberculosis_H37Rv LCGPGEAPELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTW
Mflv_2025|M.gilvum_PYR-GCK LCGPGEAPRLIDDNDTTYGGRWVVNPSGGLISKGHPLGATGLAQCSELTW
MAV_3681|M.avium_104 LCGPGEAPKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTW
Mvan_2338|M.vanbaalenii_PYR-1 LCGEGEAPKLIDAGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTW
MAB_0378|M.abscessus_ATCC_1997 LCAEGEGGKLVDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTW
MLBr_02162|M.leprae_Br4923 IPDE------------------KLNVNGGAIAMGHPLGATGAMILGTMVD
: :* .** : *.*:.*:* :
MUL_4955|M.ulcerans_Agy99 QLRGEAGDRQIDN-AK---VGLAHVIGLGSACGVHILERSAA
MMAR_0142|M.marinum_M HLRGEAGDRQIDN-AK---VGLAHVIGLGSACGVHILERSAA
MSMEG_2236|M.smegmatis_MC2_155 QLRGEAGDRQVPGEPK---VGFAQLYGAPGTAGATILTR---
TH_0532|M.thermoresistible__bu QLRGQAGDRQVPGNPK---VGFAQLYGAPGTAAATVLTT---
Mb2813c|M.bovis_AF2122/97 QLRGTAEARQVDNVT----AALQHNIGLGGAAVVTAYQRAER
Rv2790c|M.tuberculosis_H37Rv QLRGTAEARQVDNVT----AALQHNIGLGGAAVVTAYQRAER
Mflv_2025|M.gilvum_PYR-GCK QLRGTADKRQVDGVT----AALQHNIGLGGAAVVTAYQRAER
MAV_3681|M.avium_104 QLRGTADKRQVENVS----AALQHNIGLGGAAVVTAYQRAER
Mvan_2338|M.vanbaalenii_PYR-1 QLRGDADKRQVNGVT----AALQHNIGLGGAAVVTAYQRAER
MAB_0378|M.abscessus_ATCC_1997 QLRGDADKRQVASASQKTGVALQHNLGLGGACVVTAYKPANR
MLBr_02162|M.leprae_Br4923 ELERCNARR-----------ALVTLCIGAGMGVATIIERV--
.*. * .: . .