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M. thermoresistible (build 8) TH_3906 (-)

annotation: Thiolase
coordinates: 3969398 - 3970528
length: 377

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3906--100% (377)Thiolase
M. thermoresistible (build 8)TH_2654-0.092.00% (375) PUTATIVE Thiolase
M. thermoresistible (build 8)TH_2717-e-16874.39% (371) PUTATIVE thiolase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2813cltp17e-5035.77% (355) lipid-transfer protein
M. gilvum PYR-GCKMflv_2505-1e-16069.27% (371) thiolase
M. tuberculosis H37RvRv2790cltp17e-5035.77% (355) lipid-transfer protein
M. leprae Br4923MLBr_01158fadA45e-0723.32% (313) acetyl-CoA acetyltransferase
M. abscessus ATCC 19977MAB_0378-3e-4936.67% (360) lipid-transfer protein
M. marinum MMMAR_1918ltp11e-5136.97% (357) lipid-transfer protein Ltp1
M. avium 104MAV_2557-0.090.13% (375) thiolase family protein
M. smegmatis MC2 155MSMEG_4778-2e-4435.77% (383) putative thiolase
M. ulcerans Agy99MUL_2143ltp11e-5136.97% (357) lipid-transfer protein
M. vanbaalenii PYR-1Mvan_4153-1e-16170.35% (371) thiolase family protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_3906|M.thermoresistible__bu      -------------------MTPFGEHFDLGIKDLVPMA-FAEAVGNVDKG
MAV_2557|M.avium_104                ---------MRKVAIVGAGMTPFAEHFELGIKDLVPMA-YAEAVANVDKG
Mflv_2505|M.gilvum_PYR-GCK          ---------MRRAAIVGAGMTPFAEHFALGIKDLIPMA-FSACASSVDKG
Mvan_4153|M.vanbaalenii_PYR-1       ---------MRRVAIVGAGMTPFGEHFALGMKDLLPMA-FSECARTVDKG
MSMEG_4778|M.smegmatis_MC2_155      --------MTNDVAIIGVGLHPFGR---FDKPAVQMGA-EAIRLALKDAG
MMAR_1918|M.marinum_M               MPNNGS----NRVFVIGVGMTKFEKPGRREGWDYPDMARESGTNALNDAG
MUL_2143|M.ulcerans_Agy99           MPNNGS----NRVFVIGVGMTKFEKPGRREGWDYPDMARESGTNALNDAG
Mb2813c|M.bovis_AF2122/97           MPNQGSS---NKVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAG
Rv2790c|M.tuberculosis_H37Rv        MPNQGSS---NKVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAG
MAB_0378|M.abscessus_ATCC_1997      MPPKGSSKVLEKVYVIGVGMTKFEKPGRREGWDYPAMAKESGTNALTDAG
MLBr_01158|M.leprae_Br4923          --------MTTSVIVTGARTPIGKLMGSLKDFSASDLGAITIAAALKKAN
                                                                         .  :      . .

TH_3906|M.thermoresistible__bu      IEKAEIEAAWFGELSTTDG--FPSGILADTLDL-TDIPVTRIENACATGN
MAV_2557|M.avium_104                IQKSELEAAWFGELATTDG--FPSGILADTLDL-TDIPVTRVENACATGN
Mflv_2505|M.gilvum_PYR-GCK          LAKDDLQAAWIGAMGTADG--FPSGILADTLGL-PNLPVTRVENSCATGH
Mvan_4153|M.vanbaalenii_PYR-1       LSKADLQAAWFGAMGTADG--FPSGILADTLGL-PELPVTRVENSCATGH
MSMEG_4778|M.smegmatis_MC2_155      VEWKDIQFGFGGSYEVSN-----PDSVTRLVGL-TGITFTNVFNACATSA
MMAR_1918|M.marinum_M               IEYREVEHAYVG-YVYGES--TSGQRAVYELGM-TGIPVVNVNNNCSTGS
MUL_2143|M.ulcerans_Agy99           IEYREVEHAYVG-YVYGES--TSGQRAVYELGM-TGIPVVNVNNNCSTGS
Mb2813c|M.bovis_AF2122/97           IDYREVEQGYVG-YVYGES--TSGQRALYELGM-TGIPIVNVNNNCSTGS
Rv2790c|M.tuberculosis_H37Rv        IDYREVEQGYVG-YVYGES--TSGQRALYELGM-TGIPIVNVNNNCSTGS
MAB_0378|M.abscessus_ATCC_1997      IDYGKVEAAYVG-YCAGES--TSGQRAVYELGM-TGIPVTNVNNNCSTGS
MLBr_01158|M.leprae_Br4923          VAPSIVQYVIIGQVLTAGAGQMPARQAAVAAGIGWDVPALTINKMCLSGL
                                    :    ::    *                   .:   :.   : : * :. 

TH_3906|M.thermoresistible__bu      DAIRNGVLAIASGLYDVVLVVGADKVRETSSTTTFWDWAAMTRDNAWDYP
MAV_2557|M.avium_104                DAIRNGTLAIASGLYDVVLVVGADKVRETSSNTTFWDWAAMTRDNAWDYP
Mflv_2505|M.gilvum_PYR-GCK          DAIRNALFGVSSGAFDVALVIGADKLRDTTSAGMLWEWEAMARDMAWDYP
Mvan_4153|M.vanbaalenii_PYR-1       DAIRNALFGIASGAFDVALVMGADKLRDTTSAEMLWEWEAMARDMAWDYP
MSMEG_4778|M.smegmatis_MC2_155      SAIQQTADTIRLGKYDIGVAVGLDKHPRG---AFTDDPAKLALPQWYAQN
MMAR_1918|M.marinum_M               TALFLAAQAIRGGLADCTVALGFEKMKPGSLSSSYDDRTQPMDKHVKALA
MUL_2143|M.ulcerans_Agy99           TALFLAAQAIRGGLADCTVALGFEKMKPGSLSSSYDDRTQPMDKHVKALA
Mb2813c|M.bovis_AF2122/97           TALYLGAQAIRGGLADCVLALGFEKMQPGALGGGADDRESPLGRHVKALA
Rv2790c|M.tuberculosis_H37Rv        TALYLGAQAIRGGLADCVLALGFEKMQPGALGGGADDRESPLGRHVKALA
MAB_0378|M.abscessus_ATCC_1997      TALYNAAQAIRGGLADVTLALGFEKMQPGSLGATFTDREQPMQRHIEALA
MLBr_01158|M.leprae_Br4923          DAIALADQLIRAGEFDVVVAGGQESMTKAPHLLMDSRSGYKYGDVTIVDH
                                     *:      :  *  *  :. * :.                         

TH_3906|M.thermoresistible__bu      -----LGLVAPANFALHITRYLHESPATKEHMAMIAVKNHFHALKNPKAQ
MAV_2557|M.avium_104                -----LGLVAPANFALHVMRYLHESPATKEHMAMVAVKNHFHAVNNPKAQ
Mflv_2505|M.gilvum_PYR-GCK          -----LGLVAPAGFALHVRRYLHESPATEEHLAMVAVKNHRHGVNNPKAR
Mvan_4153|M.vanbaalenii_PYR-1       -----LGLVAPAGFALHVRRYLHESPATEEHLAMVAVKNHRHGVNNTKAR
MSMEG_4778|M.smegmatis_MC2_155      -----GQFVTTKFFGMKANKYLHDHNISQDTLARVANKNFRNGALNPNAF
MMAR_1918|M.marinum_M               QIAEFAFPVAPWMFGAAGREHMQQYGSTAEHFAKIGFKNHKHSVNNPFAQ
MUL_2143|M.ulcerans_Agy99           QIAEFAFPVAPWMFGAAGREHMQQYGSTAEHFAKIGFKNHKHSVNNPFAQ
Mb2813c|M.bovis_AF2122/97           EIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIGYKNHKHSVNNPYAQ
Rv2790c|M.tuberculosis_H37Rv        EIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIGYKNHKHSVNNPYAQ
MAB_0378|M.abscessus_ATCC_1997      GVFDFAFPPAPWMFGAAGREHMQKYGTTAEHFAKIGYKNHKHSVNNPYAQ
MLBr_01158|M.leprae_Br4923          ----LAYDGLHDVFTNQPMGALTEQRNDVEKFTRQEQDEFAARSHQKAAA
                                                 *       : .     : ::    .:.     :  * 

TH_3906|M.thermoresistible__bu      LRYEITVEQALAAPIIVEPFGLYDCTPQSDGAAAVILAAEEVVDR--YTD
MAV_2557|M.avium_104                LRYEITVEQALAAPIVVEPFGLYDCTPQSDGAAAVILAAEDVVDR--YTD
Mflv_2505|M.gilvum_PYR-GCK          LRFEITMEQALNAPTVVTPFRLYDCAPQSDGAAALVIASEDVVDK--FTD
Mvan_4153|M.vanbaalenii_PYR-1       LRFEITMEQALNAPTVVTPFRLYDCAPQSDGAAALVIAADDVVDR--FTD
MSMEG_4778|M.smegmatis_MC2_155      RRKEISVEEILASPTLNHPLTQYMFCAPDEGAAAVIMCRADIAHK--FTD
MMAR_1918|M.marinum_M               FQEAYTLDDILASRMIYEPLTKLQCSPTSDGSGAAILASESFVDSHGLAG
MUL_2143|M.ulcerans_Agy99           FQEAYTLDDILASRMIYEPLTKLRCSPTSDGSGAAILASESFVDSHGLAG
Mb2813c|M.bovis_AF2122/97           FQDEYTLDDILASKMISDPLTKLQCSPTSDGSAAVVLASEDYLANHNLAG
Rv2790c|M.tuberculosis_H37Rv        FQDEYTLDDILASKMISDPLTKLQCSPTSDGSAAVVLASEDYLANHNLAG
MAB_0378|M.abscessus_ATCC_1997      FQEEYTLQDILDAKEIYAPLTKLQCSPTSDGSGAAILASERFVEQNGLGD
MLBr_01158|M.leprae_Br4923          AWKDGVFADEVVPVSIPQSKGDSLQFTEDEGIRANTSAESLAGLKPAFRC
                                          . : : .  :  .       . .:*  *   .            

TH_3906|M.thermoresistible__bu      SPVWVRG-----VGIGMDRVMHQHKKDMTTFPPTVRAAKSAMKMAGLTPG
MAV_2557|M.avium_104                RPVWVRG-----VGLGMDRVMHQHKTDMTTFPPTVRAAKAAMAMAGVTPR
Mflv_2505|M.gilvum_PYR-GCK          RPVWIRG-----VGLGLDSVMHQHKPDLTTFPATTRAAKQAFAMAGMTPS
Mvan_4153|M.vanbaalenii_PYR-1       RPVWITG-----VGLGLDSVMHQHKPDLTTFPATTRAAKQAFAMAGRSPS
MSMEG_4778|M.smegmatis_MC2_155      KPVYVRASEIRTRTFGAYEVHATSAPPESDAAPTVYAARAAYEAAGIGPE
MMAR_1918|M.marinum_M               RAVEIVG--QAMTTDFASTFDG-SAKNLIGYDMNVQAAQRVYQQSGLGPE
MUL_2143|M.ulcerans_Agy99           RAVEIVG--QAMTTDFASTFDG-SAKNLIGYDMNVQAARRVYQQSGLGPE
Mb2813c|M.bovis_AF2122/97           RAVEIVG--QAMTTDFASTFDG-SARNIIGYDMTVQAAQRVYQQSGLGPK
Rv2790c|M.tuberculosis_H37Rv        RAVEIVG--QAMTTDFASTFDG-SARNIIGYDMTVQAAQRVYQQSGLGPK
MAB_0378|M.abscessus_ATCC_1997      RAVEIVG--QAMTTDIPGTLESKSAITLVGFDMAKLAAQKVYEQAQISAD
MLBr_01158|M.leprae_Br4923          GGTITPG-SASQISDGAATVVVMNKEKAQQLGLTWLVEIGAHGVVAGPDS
                                      .   .            .                .   .         

TH_3906|M.thermoresistible__bu      DIDVAEVHDCFTGV--ELISYEDLGFADRFEAYKLVEAADNYVG--GSIP
MAV_2557|M.avium_104                DIDVAEVHDCFTGV--ELISYEDLGFAHRFEAYKLVEGREHYVG--GSIP
Mflv_2505|M.gilvum_PYR-GCK          DVDVAEVHDFLTGI--ELMSYEDLGFAEKLGGYKLLEAEVTSVG--GALP
Mvan_4153|M.vanbaalenii_PYR-1       DVDVAEVHDFLTGI--ELMSYEDLGFAERLGGYKLLEAEVTSLG--GALP
MSMEG_4778|M.smegmatis_MC2_155      DVDIAQLQDTDAGA--EVIHMAETGLCADGDQEKLIAEGATEID--GSIP
MMAR_1918|M.marinum_M               DFQVIELHDCFSAN--ELLLYEALGLCGQGEAPKLIDNGDTTYG--GRWV
MUL_2143|M.ulcerans_Agy99           DFQVIELHDCFSAN--ELLLYEALGLCGQGEAPKLIDNGDTTYG--GRWV
Mb2813c|M.bovis_AF2122/97           DFGVIELHDCFSAN--ELLLYEALGLCGPGEAPELIDDNQTTYG--GRWV
Rv2790c|M.tuberculosis_H37Rv        DFGVIELHDCFSAN--ELLLYEALGLCGPGEAPELIDDNQTTYG--GRWV
MAB_0378|M.abscessus_ATCC_1997      DVDVIELHDCFSAN--ELITYEALGLCAEGEGGKLVDNGDTTYG--GRWV
MLBr_01158|M.leprae_Br4923          TLQSQPANAIKKAVDREGISVEQLDVVEINEAFAAVALASARELGIAPEL
                                     .     :    .   * :     ..         :          .   

TH_3906|M.thermoresistible__bu      INASGGLKAKGHPPGATGVAQCYELFIQLRGQAEN-QVDG-AR---VALA
MAV_2557|M.avium_104                INPSGGLKAKGHPPGATGVAQCYELFNQLRGEAEN-QVDG-AR---IALA
Mflv_2505|M.gilvum_PYR-GCK          VNPSGGLKAKGHPPGATGVAQCVELFAQLRGEAVN-QVDG-AR---IGLA
Mvan_4153|M.vanbaalenii_PYR-1       VNPSGGLKAKGHPPGATGVAQCVELFAQLRGEAVN-QVDG-AR---IGLA
MSMEG_4778|M.smegmatis_MC2_155      VNTDGGLIANGEPIGASGLRQMHELVRQLRGEAGDRQVPGNPR---VGLA
MMAR_1918|M.marinum_M               VNPSGGLISKGHPLGATGLAQCCELTWQLRGTADRRQVDDVT----AALQ
MUL_2143|M.ulcerans_Agy99           VNPSGGLISKGHPLGATGLAQCCELTWQLRGTADRRQVDNVT----AALQ
Mb2813c|M.bovis_AF2122/97           VNPSGGLISKGHPLGATGLAQCAELTWQLRGTAEARQVDNVT----AALQ
Rv2790c|M.tuberculosis_H37Rv        VNPSGGLISKGHPLGATGLAQCAELTWQLRGTAEARQVDNVT----AALQ
MAB_0378|M.abscessus_ATCC_1997      VNPSGGLISKGHPLGATGLAQCAELTWQLRGDADKRQVASASQKTGVALQ
MLBr_01158|M.leprae_Br4923          VNVNGGAIAVGHPLGMSGARITLHVALELARRGSG-----------YGVA
                                    :* .**  : *.* * :*     .:  :*   .              .: 

TH_3906|M.thermoresistible__bu      HNIGGPTAVSAVTILSSDKK-
MAV_2557|M.avium_104                HNIGGPTAVSAVTVLSNQKN-
Mflv_2505|M.gilvum_PYR-GCK          HNIGGPTAVAAVTILEGPDGG
Mvan_4153|M.vanbaalenii_PYR-1       HNIGGPTAVSAVTILEGPSGN
MSMEG_4778|M.smegmatis_MC2_155      QVYGAPGTASATILSL-----
MMAR_1918|M.marinum_M               HNIGLGGAAVVTAYQRAER--
MUL_2143|M.ulcerans_Agy99           HNIGLGGAAVVTAYQRAER--
Mb2813c|M.bovis_AF2122/97           HNIGLGGAAVVTAYQRAER--
Rv2790c|M.tuberculosis_H37Rv        HNIGLGGAAVVTAYQRAER--
MAB_0378|M.abscessus_ATCC_1997      HNLGLGGACVVTAYKPANR--
MLBr_01158|M.leprae_Br4923          ALCGAGGQGDALILRAV----
                                       *      .