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M. thermoresistible (build 8) TH_3628 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 3220074 - 3220844
length: 257

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_3628 - - 100% (257) short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8) TH_3170 - 2e-75 56.38% (243) PUTATIVE short-chain type dehydrogenase/reductase
M. thermoresistible (build 8) TH_3708 - 1e-69 52.87% (244) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2788c fabG 7e-37 35.51% (245) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCK Mflv_1202 - 1e-128 90.44% (251) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37Rv Rv2766c fabG 7e-37 35.51% (245) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923 MLBr_01807 fabG1 1e-18 28.23% (248) 3-oxoacyl-
M. abscessus ATCC 19977 MAB_4913c - 1e-69 54.51% (244) putative short chain dehydrogenase/reductase
M. marinum M MMAR_5310 - 1e-113 79.37% (252) short-chain type dehydrogenase/reductase
M. avium 104 MAV_0311 - 1e-113 79.76% (252) short-chain dehydrogenase/reductase SDR
M. smegmatis MC2 155 MSMEG_6340 - 1e-111 78.49% (251) short-chain dehydrogenase/reductase SDR
M. ulcerans Agy99 MUL_4384 - 1e-112 79.37% (252) short-chain type dehydrogenase/reductase
M. vanbaalenii PYR-1 Mvan_5605 - 1e-120 83.67% (251) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb2788c|M.bovis_AF2122/97           -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
Rv2766c|M.tuberculosis_H37Rv        -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
TH_3628|M.thermoresistible__bu      ------VVHVGYADELFDLTDRVVLITGGSRGLGREMAMAAARCGADVII
Mflv_1202|M.gilvum_PYR-GCK          --------MTGFADRLFDLTDRVVLITGGSRGLGREMAVAAAHCGADVII
Mvan_5605|M.vanbaalenii_PYR-1       -----MTASGGFADQLFDLTDRVVLVTGGSRGLGREMAFAAARCGADVVI
MMAR_5310|M.marinum_M               ---------MGYADQLFDLTDHVVLITGGSRGLGRQMAFAAARCGADVVI
MUL_4384|M.ulcerans_Agy99           ---------MGYADQLFDLTDHVVLITGGSRGLGRQMAFAAARCGANVVI
MAV_0311|M.avium_104                ---------MGYAEQLFDLADRVVLITGGSRGLGREMAFGAARCGADVVI
MSMEG_6340|M.smegmatis_MC2_155      ---------MGYADQLFDLTDRVVLITGGSRGLGREMAFGAARCGADVII
MAB_4913c|M.abscessus_ATCC_199      -----------------MLQDKVVVVTGGSRGLGRAMVRAFAAHGADVVI
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
                                                      : .:  ::**..**:*  :.   .  *  * :

Mb2788c|M.bovis_AF2122/97           TARRQE----AADEAAAQVGDRALGVGAHAVDEDAARRCVDLTLERFGSV
Rv2766c|M.tuberculosis_H37Rv        TARRQE----AADEAAAQVGDRALGVGAHAVDEDAARRCVDLTLERFGSV
TH_3628|M.thermoresistible__bu      ASRKMDNCVATAQEITEQTGRAALPYQVHVGRWDQLDGLVEAAYDRFGKV
Mflv_1202|M.gilvum_PYR-GCK          ASRKYDACVATAEEITAQTGRAALPYGVHVGRWDELDGLVDAAYARFGKV
Mvan_5605|M.vanbaalenii_PYR-1       ASRKYEACVATADEIAAETGRAAFPYQVHVGRWDELDGLVDAAYDRFGRV
MMAR_5310|M.marinum_M               ASRNLDNCVATATEIESETGRCAMAYQVHVGRWDQLDGLVAASYERFGKI
MUL_4384|M.ulcerans_Agy99           ASRNLDNCVATATEIESETGRSALAYQVHVGRWDQLDGLVAASYERFGKI
MAV_0311|M.avium_104                ASRNLDNCVATAQQIEHETGRRAMAYQVHVGRWDQLDGLVEASYDRFGKI
MSMEG_6340|M.smegmatis_MC2_155      ASRNLDSCVVTAEEIASETGRTAFPYSVHVGHWDELDGLVDAAYERFGKV
MAB_4913c|M.abscessus_ATCC_199      ASRKIDSCQELAAQVEAEHGRRALPVACNVSSWEQCDHLVDTVYREFGRV
MLBr_01807|M.leprae_Br4923          THR------------ASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPV
                                    : *                    :    ..   :     .     . * :

Mb2788c|M.bovis_AF2122/97           DILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEH
Rv2766c|M.tuberculosis_H37Rv        DILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEH
TH_3628|M.thermoresistible__bu      DVLVNNAGMSPVYDKQSDVTEQLFDAVVNLNLKGPFRLSALIGERMVADG
Mflv_1202|M.gilvum_PYR-GCK          DVLVNNAGMSPVYDKQSDVTEKLFDAVVNLNLKGPFRLSALIGERMVADG
Mvan_5605|M.vanbaalenii_PYR-1       DVLVNNAGMSPLYESLSAVTEKLFDSVVNLNLKGPFRLSVLVGDRMVADG
MMAR_5310|M.marinum_M               DTLINNAGMSPLYDKLSDVTEKLFDAVLNLNLKGPFRLSALVGERMVAAG
MUL_4384|M.ulcerans_Agy99           DTLINNAGMSPLYDKLSDVTEKLFDAVLNLNLKGPFRLSALVGERMVAAD
MAV_0311|M.avium_104                DTLINNAGMSPLYDKLTDVTEKLFDAVVNLNLKGPFRLSALVGERMVAAG
MSMEG_6340|M.smegmatis_MC2_155      DVLVNNAGMSPLYESLSAVTEKLYDAVFNLNLKGPFRLSALIGERMVADG
MAB_4913c|M.abscessus_ATCC_199      DVLVNNAGLSPLYPSLDQVSEALFDKVIGVNLKGPFRLSASIATKMAAGA
MLBr_01807|M.leprae_Br4923          EVLVANAGITSDMLIMR-MSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
                                    : *: *** ..         .  :  :..:** . :  :           

Mb2788c|M.bovis_AF2122/97           GGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSP-RIRVNAI
Rv2766c|M.tuberculosis_H37Rv        GGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSP-RIRVNAI
TH_3628|M.thermoresistible__bu      GGSIINVSTHGSLRPHPTFIPYAASKAGLNVMTEGLALAFGP-TVRVNTL
Mflv_1202|M.gilvum_PYR-GCK          GGSIVNVSTHGSLRPHPSFIPYAASKAGLNAMTEGLALAFGP-SVRVNTL
Mvan_5605|M.vanbaalenii_PYR-1       GGSIINVSTHGSIRPHPSFVPYAASKAGLNAMTEALALAYGP-TVRVNTL
MMAR_5310|M.marinum_M               GGSIINVSSAGSLRPSADIIPYAAAKAGLNAMTEGLARAFGP-TVRVNTL
MUL_4384|M.ulcerans_Agy99           GGSIINVSSAGSLRPSADIIPYAAAKAGLNAMTEGLARAFGP-TVRVNTL
MAV_0311|M.avium_104                RGSIINVSTAGSLRPTPDIVPYAASKAGLNAMTEALAKAFGP-AVRVNTL
MSMEG_6340|M.smegmatis_MC2_155      GGRIINVSSSGSLRPDQYMLPYAAAKAGLNVLTEGLAKAYGP-TVRVNTL
MAB_4913c|M.abscessus_ATCC_199      GGSIINISSIEAVRPDATALPYAAAKAGLNALTLGLSHTFGP-TVRTNTI
MLBr_01807|M.leprae_Br4923          FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVV
                                     *  :  .:  .:        * *:*:.*  ::  *:   ..  : .*.:

Mb2788c|M.bovis_AF2122/97           CPGVVRTRLAEALWKDHED-PLAATIALGRIGEPADIASAVAFLVSDAAS
Rv2766c|M.tuberculosis_H37Rv        CPGVVRTRLAEALWKDHED-PLAATIALGRIGEPADIASAVAFLVSDAAS
TH_3628|M.thermoresistible__bu      MPGPFLTDISKAWNLPEGS-NPFAGSALQRAGQPAEIVGAALFLMSDASS
Mflv_1202|M.gilvum_PYR-GCK          MPGPFLTDISNAWNFEGTD-NPFRGSALQRAGQPAEIVGAALFLMSDASS
Mvan_5605|M.vanbaalenii_PYR-1       MPGPFLTDISDAWTFTDGDTNPFGHSALQRAGQPAEIVGAALFLMSDASS
MMAR_5310|M.marinum_M               MAGPFLTDVSKAWNLDAATQNPFGHLTLRRAGNPPEIVGAALFLASDASS
MUL_4384|M.ulcerans_Agy99           MAGPFLTDVSKAWNLDAATQNPFGHLALRRAGNPPEIVGAALFLASDASS
MAV_0311|M.avium_104                MAGPFLTDVSRAWNLEAAQENPFRHLALQRAGDPREIVGAALFLASDASS
MSMEG_6340|M.smegmatis_MC2_155      MAGPFLTDVSRAWNMSGD---PFSHLALRRAGDPREIVGAALFLMSDASS
MAB_4913c|M.abscessus_ATCC_199      QCGLFNTDIAAAWP-EGFAEALIPSIPLRRVGEPEDIVGAALYLASEASA
MLBr_01807|M.leprae_Br4923          APGFIDTEMTRAMDSKYQE-AALQAIPLGRIGAVEEIAGAVSFLASEDAG
                                      * . * :: *              .* * *   :*..*. :* *: :.

Mb2788c|M.bovis_AF2122/97           WITGETMIIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv        WITGETMIIDGGLLLGNALGFRAAPSTEH
TH_3628|M.thermoresistible__bu      FTTGSIVRADGGSV---------------
Mflv_1202|M.gilvum_PYR-GCK          FTTGSIVRADGGSA---------------
Mvan_5605|M.vanbaalenii_PYR-1       FTTGSIVRADGGIP---------------
MMAR_5310|M.marinum_M               FTTGSILRADGGIP---------------
MUL_4384|M.ulcerans_Agy99           FTTGSILRADGGIP---------------
MAV_0311|M.avium_104                FTTGSILRADGGIP---------------
MSMEG_6340|M.smegmatis_MC2_155      FTTGSIVRADGGLP---------------
MAB_4913c|M.abscessus_ATCC_199      YCTGTTIRLDGGIL---------------
MLBr_01807|M.leprae_Br4923          YISGAVIPVDGGLGMGH------------
                                    : :*  :  ***

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_3628	-	-	100% (257)	short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)	TH_3170	-	2e-75	56.38% (243)	PUTATIVE short-chain type dehydrogenase/reductase
M. thermoresistible (build 8)	TH_3708	-	1e-69	52.87% (244)	PUTATIVE short-chain dehydrogenase/reductase SDR