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M. thermoresistible (build 8) TH_2580 (-)

annotation: 2-nitropropane dioxygenase, NPD
coordinates: 3849469 - 3850470
length: 334

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2580 - - 100% (334) 2-nitropropane dioxygenase, NPD
M. thermoresistible (build 8) TH_3584 - e-169 91.51% (318) PUTATIVE 2-nitropropane dioxygenase, NPD
M. thermoresistible (build 8) TH_3625 - e-157 82.66% (323) PUTATIVE 2-Nitropropane dioxygenase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3583 - 3e-38 30.57% (350) oxidoreductase
M. gilvum PYR-GCK Mflv_2128 - 1e-159 83.69% (325) 2-nitropropane dioxygenase, NPD
M. tuberculosis H37Rv Rv3553 - 3e-38 30.57% (350) oxidoreductase
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_4001c - 4e-43 33.02% (318) putative 2-nitropropane dioxygenase, NPD
M. marinum M MMAR_5042 - 8e-38 30.57% (350) 2-nitropropane dioxygenase
M. avium 104 MAV_0607 - 2e-38 31.43% (350) oxidoreductase, 2-nitropropane dioxygenase family protein
M. smegmatis MC2 155 MSMEG_5182 - 1e-158 84.50% (329) 2-nitropropane dioxygenase
M. ulcerans Agy99 MUL_4116 - 3e-37 30.29% (350) 2-nitropropane dioxygenase
M. vanbaalenii PYR-1 Mvan_4576 - 1e-161 84.97% (326) 2-nitropropane dioxygenase, NPD

CLUSTAL 2.0.9 multiple sequence alignment


Mb3583|M.bovis_AF2122/97            --MRLRTPLTELIGIEHPVVQTGMGWVAGARLVSATANAGGLG-ILASAT
Rv3553|M.tuberculosis_H37Rv         --MRLRTPLTELIGIEHPVVQTGMGWVAGARLVSATANAGGLG-ILASAT
MMAR_5042|M.marinum_M               --MRLRTPLTDLVGVEHPVVQTGMGWVAGARLVSATANAGGLG-ILASAT
MUL_4116|M.ulcerans_Agy99           --MRLRTPLTDLVGVEHPVVQTGMGWVAGARLVSATANAGGLG-ILASAT
MAV_0607|M.avium_104                MDMRLRTPLTELVGVEHPVVQTGMGWVAGARLVSATANAGGLG-ILASAT
Mflv_2128|M.gilvum_PYR-GCK          --MTITTKFTETFGVEHPIAQGGMQWVGRAELVAAVANAGALGFITALTQ
Mvan_4576|M.vanbaalenii_PYR-1       --MTIRTKFTETFGVEHPIAQGGMQWVGRAELVAAVANAGALGFITALTQ
MSMEG_5182|M.smegmatis_MC2_155      --MALTTKFTEAFGVTHPIAQGGMQWVGRAELVAAVANAGALGFITALTQ
TH_2580|M.thermoresistible__bu      --MALKTKFTEAFGVEHPIVQGGMQWVGRAELVAAVANAGALGFLTALTQ
MAB_4001c|M.abscessus_ATCC_199      ---MITNRVTELLGVERPIVQAPMGWIARSQLASAVCNAGGLGIIETSSG
                                        : . .*: .*: :*:.*  * *:. :.*.:*..***.** : : : 

Mb3583|M.bovis_AF2122/97            MTLDELAAAITKVKAVTDKPFGVNIR----ADAADAGDRVELMIREGVRV
Rv3553|M.tuberculosis_H37Rv         MTLDELAAAITKVKAVTDKPFGVNIR----ADAADAGDRVELMIREGVRV
MMAR_5042|M.marinum_M               MTLDELATAIGKVKATTDKPFGVNIR----ADAADASDRVELMIREGVKV
MUL_4116|M.ulcerans_Agy99           MTLDELATAIGKVKATTDKPFGVNIR----ADAADASDRVELMIREGVKV
MAV_0607|M.avium_104                MTLDELATAIAKVKAATDKPFGVNIR----ADAADAADRVDLMIREGVKV
Mflv_2128|M.gilvum_PYR-GCK          PTPADLANEIARTRDLTDKPFGVNLTILPAINPPPYDEYRQVIVDAGIKI
Mvan_4576|M.vanbaalenii_PYR-1       PTPADLANEIAKTRDLTDKPFGVNLTILPAINPPPYDEYRQVIVDAGIKI
MSMEG_5182|M.smegmatis_MC2_155      PTPADLANEIARCRDLTDKPFGVNLTILPSINPPPYDEYRQVIVDSGVKI
TH_2580|M.thermoresistible__bu      PTPEALAKEIARTREMTDKPFGVNLTILPTINPPPYDEYRQVIVESGIKI
MAB_4001c|M.abscessus_ATCC_199      -ELDAIKDEIRAMREFTDKPFGVNIAQAFVRDPS----IAQFVVDQGVTF
                                         :   *   :  ********:      :..      :.::  *: .

Mb3583|M.bovis_AF2122/97            ASFALAPKQQLIARLKEAGAVVIPSIGAAKHARKVAAWGADAMIVQGGEG
Rv3553|M.tuberculosis_H37Rv         ASFALAPKQQLIARLKEAGAVVIPSIGAAKHARKVAAWGADAMIVQGGEG
MMAR_5042|M.marinum_M               ASFALAPKPELIARLKEAGAVVIPSIGAAKHARKVAGWGADAMIVQGGEG
MUL_4116|M.ulcerans_Agy99           ASFALAPKPELIARLKEAGAVVIPSIGAAKHARKVAGWGADAMIVQGGEG
MAV_0607|M.avium_104                ASFALAPKQELIARLKEAGAVVIPSIGAAKHARKVAGWGADAMIVQGGEG
Mflv_2128|M.gilvum_PYR-GCK          VETAGSNPAPHLPMFHDNGIKVLHKCTSVRHAVKAQSLGVDGISIDGFEC
Mvan_4576|M.vanbaalenii_PYR-1       VETAGSNPAPHLPMFHDNGIKVLHKCTSVRHAVKAQSLGVDGISIDGFEC
MSMEG_5182|M.smegmatis_MC2_155      VETAGSNPAPHLPMFHDNGIKVLHKCTSVRHAVKAQSLGVDGISIDGFEC
TH_2580|M.thermoresistible__bu      VETAGSNPAPHLPMFHENGVKVLHKCTSVRHAVKAQSLGVDGISIDGFEC
MAB_4001c|M.abscessus_ATCC_199      VTTSAGDPNKYTRVLKDNGLTVFHVVPTLAAALKAVDAGVDGLVVEGVEG
                                    .  : .        ::: *  *:    :   * *.   *.*.: ::* * 

Mb3583|M.bovis_AF2122/97            GGHTGP--VATTLLLPSVLDAVAGTGIPVIAAGGFFDGRGLAAALCYGAA
Rv3553|M.tuberculosis_H37Rv         GGHTGP--VATTLLLPSVLDAVAGTGIPVIAAGGFFDGRGLAAALCYGAA
MMAR_5042|M.marinum_M               GGHTGP--VATTLLLPSVLDAVKGTGIPVIAAGGFFDGRGLAAALSYGAA
MUL_4116|M.ulcerans_Agy99           GGHTGP--VATTLLLPSVLDAVKGTGIPVIAAGGFFDGHGLAAALSYGAA
MAV_0607|M.avium_104                GGHTGP--VATTLLLPSVLDAVRGTGIPVIAAGGFFDGRGLAAALSYGAA
Mflv_2128|M.gilvum_PYR-GCK          AGHPGEDDVPGLVLIPAAADKIE---IPMIASGGFADGRGLAAALALGAD
Mvan_4576|M.vanbaalenii_PYR-1       AGHPGEDDVPGLVLIPAAADKIE---IPMIASGGFADARGLVAALALGAD
MSMEG_5182|M.smegmatis_MC2_155      AGHPGEDDIPGLVLIPAAADKIE---IPMIASGGFADGRGLAAALALGAD
TH_2580|M.thermoresistible__bu      AGHPGEDDIPGLVLIPAAADKIT---IPMIASGGFADARGLVAALALGAD
MAB_4001c|M.abscessus_ATCC_199      GGFKDPKGASTMVLLPLVRSHVD---IPIIAAGGICDGVSMAAAFALGAE
                                    .*. .    .  :*:* . . :    **:**:**: *. .:.**:. ** 

Mb3583|M.bovis_AF2122/97            GVAMGTRFLLTSDSTVPDAVKRRYLQAGLDGTVVTTRVDGMPHRVLRTEL
Rv3553|M.tuberculosis_H37Rv         GVAMGTRFLLTSDSTVPDAVKRRYLQAGLDGTVVTTRVDGMPHRVLRTEL
MMAR_5042|M.marinum_M               GVAMGTRFLLTSDSTVPEAVKRRYLQAALDGTVVTTRVDGMPHRVLRTGL
MUL_4116|M.ulcerans_Agy99           GVAMGTRFLLTSDSTVPDAVKRRYLQAALDGTVVTTRVDGMPHRVLRTGL
MAV_0607|M.avium_104                GVAMGTRFLLTSDSTVPDAVKKRYLEAALDGTVVTTRVDGMPHRVLRTGL
Mflv_2128|M.gilvum_PYR-GCK          GVNMGSRFMCTVESCIHQNVKEAIVAGDERGTELIFRSLHNTARVASNVV
Mvan_4576|M.vanbaalenii_PYR-1       GINMGSRFMCTVESCIHQNVKEAIVAGDERGTELIFRSLHNTARVASNEV
MSMEG_5182|M.smegmatis_MC2_155      GINMGSRFMCTVESSIHQNVKEAIVAGDERGTELIFRTLHNTARVASNKV
TH_2580|M.thermoresistible__bu      GINMGSRFMCTVESPIHQKVKEAIVAGTELDTELIFRPLRNTSRVASNAV
MAB_4001c|M.abscessus_ATCC_199      GVQMGTRMMSAAESPIHHNWKAAVVAARETDTVLLNRLTKPGLRALRSAR
                                    *: **:*:: : :* : .  *   : .   .* :  *      *.  .  

Mb3583|M.bovis_AF2122/97            VEKLESGSRARGFAAALRNAGKFRRMSQMTWRSMIRDGLTMRHGKELTWS
Rv3553|M.tuberculosis_H37Rv         VEKLESGSRARGFAAALRNAGKFRRMSQMTWRSMIRDGLTMRHGKELTWS
MMAR_5042|M.marinum_M               VEKLEGGSRARGFTAAIRNAAKFKQMSQMSWASMIKDGLAMRHGKELTWS
MUL_4116|M.ulcerans_Agy99           VEKLEGGSRARGFTAAIRNAAKFKQMSQMSWASMIKDGLAMRHGKELTWS
MAV_0607|M.avium_104                VEKLESGSPVRGLTAAVRNAAKFKHMSKMTWRSMISDGLAMRHGKEMTWS
Mflv_2128|M.gilvum_PYR-GCK          SREVVQILKEGGQFEDVKDLVAGVRGRKVFDD------------------
Mvan_4576|M.vanbaalenii_PYR-1       SREVVQILKDGGQFEDVKDLVAGVRGRKVFDD------------------
MSMEG_5182|M.smegmatis_MC2_155      SREVVEILNKGGQFEDVKDLVAGVRGRKVFEN------------------
TH_2580|M.thermoresistible__bu      SREVVEILNRGGKFEDVKDLVAGTRGAKVYET------------------
MAB_4001c|M.abscessus_ATCC_199      TEEMER--------RDLVSLLETGDPLDLYFG------------------
                                     .::            : .        .:                     

Mb3583|M.bovis_AF2122/97            QVLMAANTPMLLKAGLVDGNTEAGVLASGQVAGILDDLPSCKELIESIVL
Rv3553|M.tuberculosis_H37Rv         QVLMAANTPMLLKAGLVDGNTEAGVLASGQVAGILDDLPSCKELIESIVL
MMAR_5042|M.marinum_M               QVVMAANTPMLLKAGLVDGNPEAGVLASGQVAGILDDLPSCAQLVESIVH
MUL_4116|M.ulcerans_Agy99           QVLMAANTPMLLKAGLVDGNPEAGVLASGQVAGILDDLPSCAQLVESIVH
MAV_0607|M.avium_104                QVVMAANTPMLLKAGLVEGNTEAGVLASGQVAGILEDLPSCAELIDSIVR
Mflv_2128|M.gilvum_PYR-GCK          ------------------GDIDAGIWTVGTAMGLINDIPTVGDLVSRIVG
Mvan_4576|M.vanbaalenii_PYR-1       ------------------GDIDAGIWTVGTAMGLINDIPTVGELVSRIVG
MSMEG_5182|M.smegmatis_MC2_155      ------------------GDVDAGIWTVGTAMGLIDDIPTVQDLVTRIVR
TH_2580|M.thermoresistible__bu      ------------------GDLDAGIWWVGTSMGLINDIPTVGELVSRMVA
MAB_4001c|M.abscessus_ATCC_199      ------------------GNMETFVPLGGQVAGRIGGVESVKDILDATMD
                                                      *: :: :   *   * : .: :  :::   : 

Mb3583|M.bovis_AF2122/97            DAITHLQTASALVE--------------
Rv3553|M.tuberculosis_H37Rv         DAITHLQTASALVE--------------
MMAR_5042|M.marinum_M               DAIEHLRAAAALVE--------------
MUL_4116|M.ulcerans_Agy99           DAIEHLRAAAALVE--------------
MAV_0607|M.avium_104                DAIAHLRSASGLIEE-------------
Mflv_2128|M.gilvum_PYR-GCK          DAEEIISGRLAGMVS---PVAQRV----
Mvan_4576|M.vanbaalenii_PYR-1       EAEQLITGRLGEMVT---PTAARV----
MSMEG_5182|M.smegmatis_MC2_155      DAEVLISGRLLNMISADEPDAEKETVPA
TH_2580|M.thermoresistible__bu      EAEDLIAGRLAELIEPSVDEAGSA----
MAB_4001c|M.abscessus_ATCC_199      EFTAVIGKLAAQYV--------------
                                    :    :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2580	-	-	100% (334)	2-nitropropane dioxygenase, NPD
M. thermoresistible (build 8)	TH_3584	-	e-169	91.51% (318)	PUTATIVE 2-nitropropane dioxygenase, NPD
M. thermoresistible (build 8)	TH_3625	-	e-157	82.66% (323)	PUTATIVE 2-Nitropropane dioxygenase