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M. thermoresistible (build 8) TH_3575 (-)

annotation: acyl-CoA dehydrogenase
coordinates: 3782946 - 3783932
length: 329

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3575--100% (329)acyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_3944-1e-3635.34% (266) PUTATIVE acyl-CoA dehydrogenase, C- domain protein
M. thermoresistible (build 8)TH_4038-1e-2130.74% (270) PUTATIVE putative acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3535fadE271e-9368.46% (260) acyl-CoA dehydrogenase FADE27
M. gilvum PYR-GCKMflv_1550-7e-9871.59% (264) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv3505fadE275e-9468.85% (260) acyl-CoA dehydrogenase FADE27
M. leprae Br4923MLBr_00661fadE242e-0929.46% (129) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_4159-2e-8661.54% (260) acyl-CoA dehydrogenase
M. marinum MMMAR_4993fadE271e-9366.92% (260) acyl-CoA dehydrogenase FadE27
M. avium 104MAV_0651-4e-9468.08% (260) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_5907-1e-10068.85% (260) acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_4068fadE279e-9466.92% (260) acyl-CoA dehydrogenase FadE27
M. vanbaalenii PYR-1Mvan_5207-2e-9367.05% (264) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1550|M.gilvum_PYR-GCK          -------------------------------------MDFTTTEASEDLG
Mvan_5207|M.vanbaalenii_PYR-1       -------------------------------------MDFKTTEASEDLG
MSMEG_5907|M.smegmatis_MC2_155      -------------------------------------MDFTTTEAAADLG
Mb3535|M.bovis_AF2122/97            -------------------------------------MDFTTTEAAQDLG
Rv3505|M.tuberculosis_H37Rv         -------------------------------------MDFTTTEAAQDLG
MMAR_4993|M.marinum_M               -------------------------------------MDFSTTEAAQDLG
MUL_4068|M.ulcerans_Agy99           -------------------------------------MDFSTTEAAQDLG
MAV_0651|M.avium_104                -------------------------------------MDFTTTEAAHDLG
MAB_4159|M.abscessus_ATCC_1997      -------------------------------------MDFSLTEAQTDLA
TH_3575|M.thermoresistible__bu      -------------------------------------MDFTSTEAAEELG
MLBr_00661|M.leprae_Br4923          MTDTAPSAKPSSVRLKRGGLRSGVGMQPHKRTGFDVAIAMLTPLVGQDFL
                                                                         : :  . .  :: 

Mflv_1550|M.gilvum_PYR-GCK          ---------------GLVRTITESVCTPEHQRELDGLGP-----------
Mvan_5207|M.vanbaalenii_PYR-1       ---------------GLVRTITESVCTPEHQRELDGLRP-----------
MSMEG_5907|M.smegmatis_MC2_155      ---------------GLVRTITESVCTPEHQRELDGLP------------
Mb3535|M.bovis_AF2122/97            ---------------GLVDTIVDAVCTPEHQRELDKLE------------
Rv3505|M.tuberculosis_H37Rv         ---------------GLVDTIVDAVCTPEHQRELDKLE------------
MMAR_4993|M.marinum_M               ---------------GLVDTIVDAVCTPEHQRQLDRLE------------
MUL_4068|M.ulcerans_Agy99           ---------------GLVATIVDAVCTPEHQRQLDGLE------------
MAV_0651|M.avium_104                ---------------NLVDTIVDSVCTPEHQRELDGLD------------
MAB_4159|M.abscessus_ATCC_1997      ---------------GLTRTIASTISTPERQKELDKQD------------
TH_3575|M.thermoresistible__bu      ---------------GLVRTITESVCTHEHQRELDKLE------------
MLBr_00661|M.leprae_Br4923          DKYHLRYPLNRALRYGVKATFSTAAATSRQFKRVQNLRGGATRLQPSGRN
                                                   .:  *:  : .* .: :.::               

Mflv_1550|M.gilvum_PYR-GCK          --------------------------------DAGGRFDKTLWSKLIDAD
Mvan_5207|M.vanbaalenii_PYR-1       --------------------------------EAGGRFDRDLWGKLIDAD
MSMEG_5907|M.smegmatis_MC2_155      -----------------------------------ERFDRDLWAKLVEAD
Mb3535|M.bovis_AF2122/97            -----------------------------------QRFDRELWRKLIDAG
Rv3505|M.tuberculosis_H37Rv         -----------------------------------QRFDRELWRKLIDAG
MMAR_4993|M.marinum_M               -----------------------------------QRFDRELWRKLIDSD
MUL_4068|M.ulcerans_Agy99           -----------------------------------QRFDRELWRKLIDSD
MAV_0651|M.avium_104                -----------------------------------QRFDRDLWAKLIDAG
MAB_4159|M.abscessus_ATCC_1997      -----------------------------------SRFDRQLWTKLAEAD
TH_3575|M.thermoresistible__bu      -----------------------------------QRFDTELWAKLIDAD
MLBr_00661|M.leprae_Br4923          YFDLTPDDNQKLIVETIDEFSAEILRPAAHDADEAAAYPPDLIAKAAKLG
                                                                         :   *  *  . .

Mflv_1550|M.gilvum_PYR-GCK          VLSTTAPESLGGGGFGVLEEVAVLVALGRQLAAVPYLESVVLG---AGAL
Mvan_5207|M.vanbaalenii_PYR-1       ILSTTSPESLGGGGFGVLEEVAVLVALGRQLAAVPYLESVMLA---AGAL
MSMEG_5907|M.smegmatis_MC2_155      ILSAAAPESVGGGGFGVLEQTSVLTALGRQLAAVPYLESVVAA---AGAI
Mb3535|M.bovis_AF2122/97            ILSSAAPESLGGDGFGVLEQVAVLVALGHQLAAVPYLESVVLA---AGAL
Rv3505|M.tuberculosis_H37Rv         ILSSAAPESLGGDGFGVLEQVAVLVALGHQLAAVPYLESVVLA---AGAL
MMAR_4993|M.marinum_M               ILSSAAATQVGGDGFGVLEQVAILVALGHQLAAVPYLESVVLA---AGAL
MUL_4068|M.ulcerans_Agy99           ILSSAAATQVGGDGFGVLEQVAILVALGHQLAAVPYLESVVLA---AGAL
MAV_0651|M.avium_104                ILSSASATSLGGDGFGALEQIAILVALGHQLAAVPYLESVVLG---AGAL
MAB_4159|M.abscessus_ATCC_1997      ILSTAAPESVGGAGFGVLEQSSILVELGRELAAVPYLESVVLA---AGAL
TH_3575|M.thermoresistible__bu      VLSTAAPESIGGGGFGVLEQVAVLVALGRQLGAVPYLESVVLG---AGAL
MLBr_00661|M.leprae_Br4923          ITTINIPEYFDGIAERRSSVTNVLVAEALAYGDMGLTLPILAPGGVAATL
                                    : :   .  ..* .    .   :*.  .   . :    .::     *.::

Mflv_1550|M.gilvum_PYR-GCK          ARFGDDGLQQQWAAPAVTG--DKVLTVALDGEMGEGPVRATTTAD----G
Mvan_5207|M.vanbaalenii_PYR-1       ATFGSASLQQDWAAQAIKG--EKVLAVAFDGEMGEGPVLAQGSGD----G
MSMEG_5907|M.smegmatis_MC2_155      AEFGSDAQRAEWGAPAVAG--SKILTVALDGEMGQGPVQAQADGD----D
Mb3535|M.bovis_AF2122/97            ARFGSPELQQGWGVSAVSG--DRILTVALDGEMGEGPVQAAGTGH----G
Rv3505|M.tuberculosis_H37Rv         ARFGSPELQQGWGVSAVSG--DRILTVALDGEMGEGPVQAAGTGH----G
MMAR_4993|M.marinum_M               ARFGSEELQQSWGAAAVGG--EKILAVALDAEMGEGPVQAARSGA----G
MUL_4068|M.ulcerans_Agy99           ARFGSEELQQSWGAAAVGG--EKILAVALDAEMGEGPVQAARSGA----G
MAV_0651|M.avium_104                ARFGTEELQQGWGVPAVSG--EKTLTVALDPEMGEGPVQAVSAGA----G
MAB_4159|M.abscessus_ATCC_1997      AAFGSEAMRNDWAAPAVAG--KKVLTIALEGEPGEGPVAARTEGT----G
TH_3575|M.thermoresistible__bu      AEFGSDAQREQWAAPAVGG--QRILTAALEGETGEGPVRAEVNADS---G
MLBr_00661|M.leprae_Br4923          TYWGSADQQATYLKEFTGENVPQACVAIAEPQPLFDPTRLKTIAVRTPSG
                                    : :*    :  :          :  .   : :   .*.     .     .

Mflv_1550|M.gilvum_PYR-GCK          VTLTGTRTQVPFAVGADAFLVPAETDSGVAVFLVAAADAGVTVTPLDTTG
Mvan_5207|M.vanbaalenii_PYR-1       YTLTGSRTQVAFGVNADAFLVPAETDSGTAVFLVGSADDGVAVTALDTTG
MSMEG_5907|M.smegmatis_MC2_155      HRLTGSRTLVSYGPVADAYLVPAETGSGVSVFIVAADDAGVTETSLNTTG
Mb3535|M.bovis_AF2122/97            YRLTGTRTQVGYGPVADAFLVPAETDSGAAVFLVAAGDPGVAVTALATTG
Rv3505|M.tuberculosis_H37Rv         YRLTGTRTQVGYGPVADAFLVPAETDSGAAVFLVAAGDPGVAVTALATTG
MMAR_4993|M.marinum_M               FRLTGTRTQVGYGPVADAFLVPAETDSGTVVFLVAADDPGVSVTALQTTG
MUL_4068|M.ulcerans_Agy99           FRLTGTRTQVGYGPVADAFLVPAETDSGTVVFLVAADDPGVSVTALQTTG
MAV_0651|M.avium_104                YRLTGTRTQVGFGPVADAFLVPAETDSGTAVFLVAADDPGVTVTALETTG
MAB_4159|M.abscessus_ATCC_1997      YVLTGNRVLVPFGVEADAYLVPAETETGTAVFLVSADDAGVTQQALHTTG
TH_3575|M.thermoresistible__bu      HTLTGTRTLVRFGPVADGFLVPAETDSGTRVFLVAADDPGVTVTALNTTG
MLBr_00661|M.leprae_Br4923          YRLDGVKSLVPAAASAELFIIGAQLNGKPALFIVESSTKGLTVKADPSMG
                                      * * :  *  .  *: ::: *:      :*:* :   *::  .  : *

Mflv_1550|M.gilvum_PYR-GCK          H--GSVAALDLQGVGITGDRRVG---GSE-VLDWLVTRNALARSAYQLGV
Mvan_5207|M.vanbaalenii_PYR-1       H--GSVAGLQLQGVAIGSDRRVG---GPE-VLDWLVTRHALGRSAYQLGV
MSMEG_5907|M.smegmatis_MC2_155      K--GSVAHLDLQDVAVGADRVLG---GTQ-VAEWLTTRVTLGRTAYQLGV
Mb3535|M.bovis_AF2122/97            L--GSVGHLELNGAKVDAARRVG---GTD-VVVWLGTLSTLSRTAFQLGV
Rv3505|M.tuberculosis_H37Rv         L--GSVGHLELNGAKVDAARRVG---GTD-VAVWLGTLSTLSRTAFQLGV
MMAR_4993|M.marinum_M               L--GSVGHLALDGTEVDAARGIG---GSD-VTAWLRTINTLGRSAFQLGV
MUL_4068|M.ulcerans_Agy99           L--GSVGHLALDGTEVDAARGIG---GSD-VTAWLRTINTLGRSAFQLGV
MAV_0651|M.avium_104                L--GSVGHLALDGTQVDGTRQVG---GAE-VAAWLGTLGTLGRAAFQLGV
MAB_4159|M.abscessus_ATCC_1997      K--DSSAELILSEVPVPAERKVG---GAE-VVEWLRLRESLGHSAYQLGV
TH_3575|M.thermoresistible__bu      R--GSVGRLELAGTVLPPDRTVG---ADEAALRWIKIRNILGHSAFQLGV
MLBr_00661|M.leprae_Br4923          IRAAALGQVELCGVSAPLDARLGEDDATDNDYSEAIALARLGWAALAVGT
                                        : . : *  .       :*   . :           *. :*  :*.

Mflv_1550|M.gilvum_PYR-GCK          VERALELTAQYAREREQFDRPIGSFQAVSSRLADGYIDIKGLRLTVTQAA
Mvan_5207|M.vanbaalenii_PYR-1       LERALELTASYAREREQFDRPIGSFQAVSSRLADGYIDIKGLRLTLTQAA
MSMEG_5907|M.smegmatis_MC2_155      LERALELTASYAREREQFDRPIGSFQAVSSRLADGYIDVKGLRLTLTQAA
Mb3535|M.bovis_AF2122/97            LERGLQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAA
Rv3505|M.tuberculosis_H37Rv         LERGLQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAA
MMAR_4993|M.marinum_M               LERGLRMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAA
MUL_4068|M.ulcerans_Agy99           LERGLQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAA
MAV_0651|M.avium_104                LERGLQMTAEYARTREQFDRPIGSFQAVSQRLADGYIDVKGLRLTLTQAA
MAB_4159|M.abscessus_ATCC_1997      LERALELTADYARTREQFGKPIGGFQAVAQRLADGYIDVKGLCLTLWQAA
TH_3575|M.thermoresistible__bu      LERALEMTAAYAREREQFDRPLX---XXAGGCAGGGVPAG----------
MLBr_00661|M.leprae_Br4923          SHAVLDYVMPYVKEREAFGEPIARRQAVAFMCANIAIELDGLRLITWRGA
                                     .  *  .  *.: ** *..*:      .   *.  :             

Mflv_1550|M.gilvum_PYR-GCK          WRVSED--------LPADVDVASAAFWAAEAGHRVAHTAVHVHGGVGIDI
Mvan_5207|M.vanbaalenii_PYR-1       WRLSED--------LPADLDVASAAFWAAEAGHRVAHTTVHVHGGVGIDI
MSMEG_5907|M.smegmatis_MC2_155      WRLSED--------LPADVDVASAAFWAAEAGHRVAHTAVHVHGGVGIDM
Mb3535|M.bovis_AF2122/97            WRVAEDSLASRECPQPADIDVATAGFWAAEAGHRVAHTIVHVHGGVGVDT
Rv3505|M.tuberculosis_H37Rv         WRVAEDSLASRECPQPADIDVATAGFWAAEAGHRVAHTIVHVHGGVGVDT
MMAR_4993|M.marinum_M               WRVSED--------LPAEIDVASAGFWAAEAGHRVAHTIVHVHGGVGVDT
MUL_4068|M.ulcerans_Agy99           WRVSED--------LPAEIDVASAGFCAAEAGHRVAHTIVHVHGGVGVDT
MAV_0651|M.avium_104                WRVSED--------LPAEVDVATAAFWAADAGHRVAHTIVHVHGGVGVDT
MAB_4159|M.abscessus_ATCC_1997      WRVSED--------LPSDVDVATAKFWAADAGHRVAHTAVHVHGGVGIDE
TH_3575|M.thermoresistible__bu      --------------RPGHRGAAVGGGRAGPSG-RTAHPGRPGH-------
MLBr_00661|M.leprae_Br4923          SRAEQG--------LSFAREAALAKRLGSDKAMQIGLDGVQLLGGHGFIK
                                                   .    .* .   ..  . : .              

Mflv_1550|M.gilvum_PYR-GCK          DHPVHRYFLAAKQTEFAVGGATGQLLRIGRELADTPA
Mvan_5207|M.vanbaalenii_PYR-1       DHPVHRYFLAAKQTEFAVGGATGQLLRIGRELADTPA
MSMEG_5907|M.smegmatis_MC2_155      DHPVHRYFLAAKQSEFALGSATGQLLRIGRELADTPV
Mb3535|M.bovis_AF2122/97            DHPVHRYFLAAKQTEFALGGATGQLRRIGRELAETPA
Rv3505|M.tuberculosis_H37Rv         DHPVHRYFLAAKQTEFALGGATGQLRRIGRELAETPA
MMAR_4993|M.marinum_M               DHPVHRYFLAAKEAEFALGGATTALRQIGRELAETPA
MUL_4068|M.ulcerans_Agy99           DHPVHRYFLAAKEAEFALGGATTALRQIGRELAETPA
MAV_0651|M.avium_104                DHPVHRYFLAAKQAEFALGGATGQLRRIGRELAETPA
MAB_4159|M.abscessus_ATCC_1997      DHPVHRYFLAAKRGEFASGSATEQLRRIGRELADTPA
TH_3575|M.thermoresistible__bu      ---LRRRARDGVQDAAGRCADGGGARRW---------
MLBr_00661|M.leprae_Br4923          EHPVERWYRDLR----AIGVAEGVVVI----------
                                       :.*          .