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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3555 | - | - | 100% (235) | - |
| M. thermoresistible (build 8) | TH_0771 | - | 7e-06 | 30.36% (112) | CONSERVED HYPOTHETICAL PROTEIN |
| M. thermoresistible (build 8) | TH_3756 | - | 1e-05 | 20.60% (199) | PUTATIVE putative conserved lipoprotein LppH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1297c | pknH | 1e-17 | 25.54% (231) | transmembrane serine/threonine-protein kinase H |
| M. gilvum PYR-GCK | Mflv_2675 | - | 2e-11 | 21.20% (217) | hypothetical protein Mflv_2675 |
| M. tuberculosis H37Rv | Rv1266c | pknH | 3e-17 | 25.54% (231) | transmembrane serine/threonine-protein kinase H |
| M. leprae Br4923 | MLBr_02320 | - | 8e-05 | 28.83% (111) | hypothetical protein MLBr_02320 |
| M. abscessus ATCC 19977 | MAB_0361 | - | 5e-09 | 25.52% (192) | hypothetical protein MAB_0361 |
| M. marinum M | MMAR_4171 | - | 4e-17 | 28.00% (200) | transmembrane serine/threonine-protein kinase |
| M. avium 104 | MAV_1417 | - | 2e-14 | 26.84% (231) | serine/threonine-protein kinase PknE |
| M. smegmatis MC2 155 | MSMEG_4554 | - | 2e-11 | 23.28% (232) | serine/threonine-protein kinase PknH, putative |
| M. ulcerans Agy99 | MUL_4150 | lppH | 5e-13 | 27.23% (213) | lipoprotein LppH |
| M. vanbaalenii PYR-1 | Mvan_3880 | - | 2e-13 | 24.22% (223) | hypothetical protein Mvan_3880 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1297c|M.bovis_AF2122/97 MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAE
Rv1266c|M.tuberculosis_H37Rv MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAE
MMAR_4171|M.marinum_M MSDAQGSRVGSTFGPYRLTRLLGRGGMGEVYEAEHTVKEWTVAVKLMSET
MAV_1417|M.avium_104 MSDERSSKVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLLNES
Mflv_2675|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02320|M.leprae_Br4923 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 FSKDPVFRERMKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTD
Rv1266c|M.tuberculosis_H37Rv FSKDPVFRERMKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTD
MMAR_4171|M.marinum_M FSKDPVFRERMKREARITGRLQEPHVVPIHDYGEIDGQMYLEMRLIEGTD
MAV_1417|M.avium_104 FSSDPVFRERMKREARTAGRLQEPHVVPVHDYGEIDGQMFLEMRLVEGTD
Mflv_2675|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02320|M.leprae_Br4923 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 LDSVLKRFGPLTPPRAVAIITQIASALDAAHADGVMHRDVKPQNILITRD
Rv1266c|M.tuberculosis_H37Rv LDSVLKRFGPLTPPRAVAIITQIASALDAAHADGVMHRDVKPQNILITRD
MMAR_4171|M.marinum_M LDNLLKRFGPLTPPRAVAIITQVASALDAAHAAGVMHRDVKPQNILVTRE
MAV_1417|M.avium_104 LDSVLKRFGPLPPPRAVAIITQIASALDAAHAAGVMHRDVKPQNILVTRD
Mflv_2675|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02320|M.leprae_Br4923 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 DFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYA
Rv1266c|M.tuberculosis_H37Rv DFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYA
MMAR_4171|M.marinum_M DFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYA
MAV_1417|M.avium_104 DFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSDAEVTYRADIYA
Mflv_2675|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02320|M.leprae_Br4923 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 LACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVV
Rv1266c|M.tuberculosis_H37Rv LACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVV
MMAR_4171|M.marinum_M LACVLHECLTGSPPYRADSASMLVTAHMMDPIPQPSTVRAGIPKAFDTVI
MAV_1417|M.avium_104 LACVLFECLTGSAPYRADSAGVLVSAHVMDPIPAPSARRPGVPKAFDAVI
Mflv_2675|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02320|M.leprae_Br4923 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 ARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPG--
Rv1266c|M.tuberculosis_H37Rv ARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPP
MMAR_4171|M.marinum_M ARGMAKQPGDRYASAGDLALAAHEALSNPDQDHAADILRRSQEATLPGPP
MAV_1417|M.avium_104 ARGMAKKPEDRYASAGDLALAAKEALSTPDQDRAATILRRSQEAALPAAG
Mflv_2675|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02320|M.leprae_Br4923 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 ---------TAAVTAQPPTMPTVTPPPIQAAP------------------
Rv1266c|M.tuberculosis_H37Rv KPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAG----
MMAR_4171|M.marinum_M DPAAPPTMPATAAAPPARPGPAATPPRPAPTPQQPPYYPAAAAPAAGSPP
MAV_1417|M.avium_104 QR-------DAGASTVLAPPPAVNTRQPGSAAS-----------------
Mflv_2675|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02320|M.leprae_Br4923 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 ------------------------------TGQPSWAPNSGPMPASGPTP
Rv1266c|M.tuberculosis_H37Rv -------------------------QRPGPTGQPSWAPNSGPMPASGPTP
MMAR_4171|M.marinum_M SGPSAVAGPPRGVAPSGPAGPSGPIPRPPAAGQPGWQQASGPIPASQPTP
MAV_1417|M.avium_104 ------------------------------QAGRGWTPESGPIPAAG-QP
Mflv_2675|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3880|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4554|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4150|M.ulcerans_Agy99 --------------------------------------------------
TH_3555|M.thermoresistible__bu --------------------------------------------------
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02320|M.leprae_Br4923 --------------------------------------------------
Mb1297c|M.bovis_AF2122/97 TPQYYQGGGWG-APPSG---GPSPWAQTP-----RKTNPWPLVAGAAAVV
Rv1266c|M.tuberculosis_H37Rv TPQYYQGGGWG-APPSG---GPSPWAQTP-----RKTNPWPLVAGAAAVV
MMAR_4171|M.marinum_M SPPYYQGAGWGGAPPPGQPAGPSTWNQGPQGPGPRGRNPWPIVA-AVAIV
MAV_1417|M.avium_104 GPPYYQGGNANWAAAPAQFAGPPPWGRPP-----PKRRVWPIVA-AVVAV
Mflv_2675|M.gilvum_PYR-GCK --------------------------------------------MTALML
Mvan_3880|M.vanbaalenii_PYR-1 ----------------------------------------MALAGLAVSL
MSMEG_4554|M.smegmatis_MC2_155 -----------------------------MTPGRRWTRLCTAGAAAAVMC
MUL_4150|M.ulcerans_Agy99 ---------------------------------MRQRVAALAALVGGAGM
TH_3555|M.thermoresistible__bu -------------------------------MTKLTRRILGGCAAAVVVL
MAB_0361|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02320|M.leprae_Br4923 -------------------------------------------------M
Mb1297c|M.bovis_AF2122/97 LVLVLGAIGIWIANRP-KPVQP-PQPVAEERLSALLLNSSEVNAVMGSSS
Rv1266c|M.tuberculosis_H37Rv LVLVLGAIGIWIAIRP-KPVQP-PQPVAEERLSALLLNSSEVNAVMGSSS
MMAR_4171|M.marinum_M LVLIVGGIGVWMITQPPKPSPP-PKPIAEDRLSSLLLSPAEVNSVMGASN
MAV_1417|M.avium_104 LVVIAGGVGVWLVIRP-KPEPPQAAPLTSDRLGALLLSASEVNAVMGSST
Mflv_2675|M.gilvum_PYR-GCK PMTACVETVDGTALRGHGAGLTDVAPLDESRLDSVLVGIDEINSIMGATG
Mvan_3880|M.vanbaalenii_PYR-1 WATACTSTVDGTAVRPDAAPSAVAGVLTERDLDAVLLDSAEIAALLNSPD
MSMEG_4554|M.smegmatis_MC2_155 LLSGCVTVVGGTATR-DPAAPPPGAAVTEVDLDNLLLPVTELGDIVGSDD
MUL_4150|M.ulcerans_Agy99 LVTGCTNIVDGNAVAADMSGPLNQTPIAVSALDDLLLDVSQIDSALGATS
TH_3555|M.thermoresistible__bu TGAACTHSVEGSAVYAPEVPRDDLPLVKIAELRDLIPTADEARTVVEAPN
MAB_0361|M.abscessus_ATCC_1997 ----MTIVLSAALACAAPALAEQGSPIPPAAIDDLMVTPDEASSVMKTG-
MLBr_02320|M.leprae_Br4923 SWVIRISAVVMSVGLGLGVPVASARPSEPGVVSYAVLGKGSVGNIIGRPM
: : . :
Mb1297c|M.bovis_AF2122/97 MQPGKPITSMDSSP-VTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSE
Rv1266c|M.tuberculosis_H37Rv MQPGKPITSMDSSP-VTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSE
MMAR_4171|M.marinum_M IQPGKPITSMDASP-VTLSLPECQGALYTSQDPVYSGTGYTAISGLVASE
MAV_1417|M.avium_104 MEPGKPITATDSSS-VTVSVPDCQGALYTTQDPVYAGSGYSAVNGLVSSE
Mflv_2675|M.gilvum_PYR-GCK MEVTGELDEMSDHS-ADVSDPDCLGAVYGAEAPVYEGTDWTAVRDQVARE
Mvan_3880|M.vanbaalenii_PYR-1 IEVTDEIDEMTDTS-ADVSNPECLGALYTAEDPVYESTGYTAVLTRLASE
MSMEG_4554|M.smegmatis_MC2_155 LTVTVELDQFNDSS-AAMDDPDCLAAAFGAQERVYAGTGWTAVRDQIVRE
MUL_4150|M.ulcerans_Agy99 MKVWFNAKAMWDWS-KNISDKNCLAVDGPAQDEVYAGTGWTAMRGQRMDD
TH_3555|M.thermoresistible__bu LIYLLAYTKPDSLPPDMLSEPECASAVIPNDASAYRGSGYAAVYGRLADD
MAB_0361|M.abscessus_ATCC_1997 ---FPVVDRFNALSALTTDRPDCGSVVLPS-VATYDRGPYMAAHQQYLQD
MLBr_02320|M.leprae_Br4923 GWESLLTEPLQAYS---VDLPMCNNWADIGLPEVYHDVDLASFNGAITQT
. . * .* :
Mb1297c|M.bovis_AF2122/97 PGDNYE---HWVNQAVVAFPTADKARAFVQTSADKWKNCAG-KTVTVTNK
Rv1266c|M.tuberculosis_H37Rv PGDNYE---HWVNQAVVAFPTADKARAFVQTSADKWKNCAG-KTVTVTNK
MMAR_4171|M.marinum_M PGDNND---HWVNQAVVSFPSAAKASSFVETMAGKWKNCAG-KTVTVTNK
MAV_1417|M.avium_104 PGDNYD---HWVNQAVVLFPSADKAKSFLQTSLQKWKGCAG-QTVTVTNK
Mflv_2675|M.gilvum_PYR-GCK PGAGND---HWVEQAVVLYPEERNARDFLESSQAVWRDCAN-NALGVGD-
Mvan_3880|M.vanbaalenii_PYR-1 PGDDNE---HWVEESAVLVPTAEDAEQFVERSAREWDDCAG-RQVSISDG
MSMEG_4554|M.smegmatis_MC2_155 PGSFSP---HWIEQVVVLFTSDLHARDFFDQSRETWRGCVG-TLTTYDID
MUL_4150|M.ulcerans_Agy99 SVDDSKRRKHYAIQAVVAFPSAHDASAFYNSSVRSWGNCSNRRFTDVSTD
TH_3555|M.thermoresistible__bu LR------SHRISTGVAAFAGAQEAHEWVTQQVDRWRDCTD-RTLTISLN
MAB_0361|M.abscessus_ATCC_1997 SAPWNV----QLAQSIAVFPTDDEARDFASTEMDMWLKCSK----HTVHD
MLBr_02320|M.leprae_Br4923 SANDQT---HFVKQAVGVFATNDAAVRAFHRVVDRTVGCSGQTTAMHLDN
. * *
Mb1297c|M.bovis_AF2122/97 AKTYRWTFADVKGSPPTIT--VIDTQEGAEGWECQRAMSVANNVVVDVNA
Rv1266c|M.tuberculosis_H37Rv AKTYRWTFADVKGSPPTIT--VIDTQEGAEGWECQRAMSVANNVVVDVNA
MMAR_4171|M.marinum_M SKTYRWTFAQVVGSPPRIT--MLETQEGAEGWECQRAMSVANNVIVDINS
MAV_1417|M.avium_104 SKTYRWTFAQVQGAPPKIT--LMDTQEGADGWECQRALSVANNVIVDINA
Mflv_2675|M.gilvum_PYR-GCK ---YLWELGAVEAADLMLT--QVTTQEGADGWSCQHALSLVSNVTVEAWA
Mvan_3880|M.vanbaalenii_PYR-1 EEWFDWELDAVVRDGGMVS--QQSTILDSIDWQCQHTVVSVSNLIIEASV
MSMEG_4554|M.smegmatis_MC2_155 QMPLEWVVGEVTAEESTIS--QLSVPETAVRGGCHHALSVAANLVAEAWA
MUL_4150|M.ulcerans_Agy99 QPDTIWTVSDVVNDNGMLS--TSQVQEAGDGWTCQRALTVRNNVAIDVVT
TH_3555|M.thermoresistible__bu GQELQWKTSGPTRAEGVHV--LLRRQEGTD-YACSRGVAARSNVAADVLV
MAB_0361|M.abscessus_ATCC_1997 SAQWRYAIGSLHRDDDAVVGSYVMITNDGARMSCSRLLARVRNTATDLRA
MLBr_02320|M.leprae_Br4923 GTTQVWSFVGGTPTYADAN---WTKQEAGTDRRCFVQTRLRENVLLQTKV
: * * :
Mb1297c|M.bovis_AF2122/97 CGYQITN---QAGQIAAKIVDKVNKE---
Rv1266c|M.tuberculosis_H37Rv CGYRITN---QAGQIAAKIVDKVNKE---
MMAR_4171|M.marinum_M CGYHITD---QGGALADKIVDKIHKETKY
MAV_1417|M.avium_104 CGYRITD---QGDQIADKIVAKIDNE---
Mflv_2675|M.gilvum_PYR-GCK CGYDITD---EAARIADAMIRNAAG----
Mvan_3880|M.vanbaalenii_PYR-1 CAERIHD---EATTVVAEMIAKASARTR-
MSMEG_4554|M.smegmatis_MC2_155 CGEGVED---QASEIVDQIVANIE-----
MUL_4150|M.ulcerans_Agy99 CAYSQSGS--VAADVAQQIAAKAAKQ---
TH_3555|M.thermoresistible__bu CGRNPEAVNPQAGKLANLMLSKIGD----
MAB_0361|M.abscessus_ATCC_1997 CSAGPES-YQRLLGIAKIIGPRYDAA---
MLBr_02320|M.leprae_Br4923 CQPGNAG--PAVNVLAGAMQNALGQ----
* :. :