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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3536 | - | - | 100% (445) | transcriptional regulator, TetR family |
| M. thermoresistible (build 8) | TH_2070 | - | 9e-14 | 35.90% (156) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. thermoresistible (build 8) | TH_0256 | - | 6e-10 | 35.37% (164) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3587c | - | 1e-13 | 33.94% (165) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4158 | - | 1e-152 | 63.62% (426) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3557c | - | 1e-13 | 33.94% (165) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 4e-05 | 34.19% (117) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0599 | - | 8e-15 | 37.25% (153) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4325 | - | 1e-162 | 69.34% (411) | TetR family transcriptional regulator |
| M. avium 104 | MAV_1265 | - | 1e-159 | 69.16% (415) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6009 | - | 1e-13 | 43.93% (107) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0135 | - | 1e-129 | 68.88% (331) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5283 | - | 1e-13 | 33.13% (163) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4325|M.marinum_M ------------MADHRDQAGTD-----------DSGTRRTEILQTAAAL
MUL_0135|M.ulcerans_Agy99 ------------MADHRDQAGTD-----------DSGTRRTEILQTAAAL
MAV_1265|M.avium_104 ----------MAKAESLRTGSTA-----------DSPTRRAEILATAASL
TH_3536|M.thermoresistible__bu -----VVGRPQLTSEQRNVRKSAHTLASVAGRAYDDGTRRTEILQTAARL
Mflv_4158|M.gilvum_PYR-GCK MAADAAGQKPGRGRRAGRKRSGSAELAAVRDAAPADTTRRAEILKTANTV
Mb3587c|M.bovis_AF2122/97 ------------MDR-VAGQVN---------------SRRGELLELAAAM
Rv3557c|M.tuberculosis_H37Rv ------------MDR-VAGQVN---------------SRRGELLELAAAM
Mvan_5283|M.vanbaalenii_PYR-1 ------------MSSGQAPQAN---------------TRRDELLQLAATM
MSMEG_6009|M.smegmatis_MC2_155 ------------MAPDTPSQPA---------------SRRDELLQLAATM
MAB_0599|M.abscessus_ATCC_1997 ------------MDKVSEVRESD----ALRAGGSPQPSRRDELLSLAAEM
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQ----------LSGDDREQAILAVAERL
*. :* * :
MMAR_4325|M.marinum_M IASSGLR-TSLQEIADAAGILPGSLYHHFESKEAILIELIRRYQDDLHQI
MUL_0135|M.ulcerans_Agy99 IASSGLR-TSLQEIADAAGILPGSLYHHFESKEAILIELIRRYQDDLHQI
MAV_1265|M.avium_104 IASSGLR-TSLQEIADAAGILPGSLYHHFESKEAILVELIRRYQDDLERI
TH_3536|M.thermoresistible__bu IASSGLR-TSLQEIADAAGILPGSLYHHFESKEAILVELLRRYHTDLDTI
Mflv_4158|M.gilvum_PYR-GCK IAATGLR-SSLQQIADAAGILAGSLYHHFDSKEAILVELIRLYHDDLDRI
Mb3587c|M.bovis_AF2122/97 FAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFAR
Rv3557c|M.tuberculosis_H37Rv FAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFAR
Mvan_5283|M.vanbaalenii_PYR-1 FAERGLRATTVRDIADSAGILSGSLYHHFSSKEEMVDEVLRGFLDWLFDR
MSMEG_6009|M.smegmatis_MC2_155 FADRGLKATTVRDIADSAGILSGSLYHHFKSKEQMVEEVLRDFLDWLFGR
MAB_0599|M.abscessus_ATCC_1997 FAERGLRATTVRDIADAAGILSGSLYHHFDSKEAIVDELLRDFLEGLFAR
MLBr_01070|M.leprae_Br4923 LAERPLGDFSVDELAKGAGISRPTFYFYFPSKNAVLLSLL----DDLNMK
:* * :: ::*..*** ::*.:* **: :: .:: *
MMAR_4325|M.marinum_M GQSWQAKLDQPDSRTVAEKITQLGAAIANCAVAHRAALQMSFYEGP-SAD
MUL_0135|M.ulcerans_Agy99 GQSWQAKLDQPDSRTVAEKITQLGAAIANCAVAHRAALQMSFYEGP-SAD
MAV_1265|M.avium_104 GRTAQARLDEPDSRPVPEQIIELGSAIANCAVEHRAALQMSFYEGP-GTD
TH_3536|M.thermoresistible__bu AAHAQERLDDPDPRSPSDRITDLGVAIARCAVTHRAALQMTFYEGP-TSH
Mflv_4158|M.gilvum_PYR-GCK GDLALRKLDEPDPEPVSAQITALGCAIARCAVEHRAALQMSFYEGP-SAD
Mb3587c|M.bovis_AF2122/97 YRDIVDSTANP-----LERLQGLFMASFEAIEHHHAQVVIYQDEAQRLAS
Rv3557c|M.tuberculosis_H37Rv YRDIVDSTANP-----LERLQGLFMASFEAIEHHHAQVVIYQDEAQRLAS
Mvan_5283|M.vanbaalenii_PYR-1 YQQIVATEPNP-----LERLKGLFMASFEAIETRHAEVVIYQDEAKRLSA
MSMEG_6009|M.smegmatis_MC2_155 YQQILDTATSP-----LEKLTGLFMASFEAIEHRHAQVVIYQDEAKRLSD
MAB_0599|M.abscessus_ATCC_1997 YREIAAANLNP-----VDTLKGLFLASFDAIETKHAQVAIYQAEAPRLLS
MLBr_01070|M.leprae_Br4923 SRSAVEALAEQLPADPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPE
. * ::*
MMAR_4325|M.marinum_M PE-LMKLTSQRPLAIQEAMLQTLRAGRWSGCIRTEIDLPTLADRICQT-M
MUL_0135|M.ulcerans_Agy99 PE-LMKLTSQRPLAIQEAMLQTLRAGRWSGYIRTEIDLPTFADRICQT-M
MAV_1265|M.avium_104 PE-LTKLTRQRPVAIQEAMLQTLRAGRWSGYIKPDIDLPTLADRICQT-M
TH_3536|M.thermoresistible__bu PE-VTALAQQRPTGILEAMLQTLRAARWSGYLRADIDLPILADRIVQT-M
Mflv_4158|M.gilvum_PYR-GCK PE-LQALSARAPEKVQAAMLQALRAGRWSGEIRSDVDLPTLADRLCQS-M
Mb3587c|M.bovis_AF2122/97 QP-RFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTW
Rv3557c|M.tuberculosis_H37Rv QP-RFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTW
Mvan_5283|M.vanbaalenii_PYR-1 QG-RFAYVEERNKEQRKMWVDVLTQGIDEGYFRPDVDVDLVYRFIRDTTW
MSMEG_6009|M.smegmatis_MC2_155 LP-QFDFVETRNKEQRKMWVDILQEGVADGSFRPDLDVDLVYRFIRDTTW
MAB_0599|M.abscessus_ATCC_1997 QE-RFAYLNELNTEQRQLWLEVLRDGIAQGYFRPDLDVAVVYRFIRDATW
MLBr_01070|M.leprae_Br4923 VRRLWSTVMQQWIDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTER-V
:: . *: : :
MMAR_4325|M.marinum_M LQVGLDMMRRNASADQVSGLMCRTILQGLASHAPTDVDLDGSNALSAAND
MUL_0135|M.ulcerans_Agy99 LQVGLDMMRRNASADQVSGLMCRTILQALASHAPTDVDPDGSNALSAAND
MAV_1265|M.avium_104 LQVGLDVMRHTASADQVAELLCRIILQGLASRPPSDAALDRSKAFVAANE
TH_3536|M.thermoresistible__bu LQVGLDVIRHNASPDKAATLLCRILLEGLATVLPTDEELDGSAAFRAADE
Mflv_4158|M.gilvum_PYR-GCK LHVGLDVIRHKARTDDLATLKCRIALNGLASEAPSDASLDRSKAFAAAQS
Mb3587c|M.bovis_AF2122/97 VSVRWYRPGGPLTAQQVGQQYLAIVLGGITKEGV----------------
Rv3557c|M.tuberculosis_H37Rv VSVRWYRPGGPLTAQQVGQQYLAIVLGGITKEGV----------------
Mvan_5283|M.vanbaalenii_PYR-1 VSVRWYQPGGPLTAQQVGRQYLSIVLGGITAEPTSKESTNG---------
MSMEG_6009|M.smegmatis_MC2_155 VSVRWYKPGGPLSAEQVGQQYLAIVLGGITQSQGDKHA------------
MAB_0599|M.abscessus_ATCC_1997 VSVRWFRPGGSRTAQEVAEQYLSIVLGGITVGSFSNSPEK----------
MLBr_01070|M.leprae_Br4923 MAATFSDEKPLIPDKKVIDTLVHIWLASIYGS------------------
: . .. * .:
MMAR_4325|M.marinum_M VIATWIDEKDADPSDKAAHVRAVARIEFGRKGYEVTTIRDIASASGLATG
MUL_0135|M.ulcerans_Agy99 VIATWIDEKDTDPSDKAAHVRAVARMEFGRKGYEVTTVRDIASASGLGTG
MAV_1265|M.avium_104 VIETWSDDSDADPGDKAALVRAVARAEFGRRGYEVTTIRDIAAAAGLGTG
TH_3536|M.thermoresistible__bu VVQSWSLEAEAEADDKAAHVRAVARAEFGRRGYEGTTIRDIARAAGLGTG
Mflv_4158|M.gilvum_PYR-GCK VISTWADD-EDETDLKAAHLRAVARAEFGRRGYEMTTIRDIASAAGLGTG
Mb3587c|M.bovis_AF2122/97 --------------------------------------------------
Rv3557c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_5283|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6009|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0599|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01070|M.leprae_Br4923 --------------------------------------------------
MMAR_4325|M.marinum_M TVYRVIGSKDKLLASIMRSFGQKVEAGWVAVLRSNATPIEKLDALSWVNI
MUL_0135|M.ulcerans_Agy99 TVYRVIGSKDKLLASIMRSFGQKVEAGWVAVRRSNATPIEKLDALSWVNI
MAV_1265|M.avium_104 TVYRVIGSKDELLDSIMRSFGKKVEAGWVSVLRSDATPTEKLDALSWVNV
TH_3536|M.thermoresistible__bu TVYRLIGSKEELLASIMRSFGEKIAVGWTDVLRTDAPAIAKLDALSWVNT
Mflv_4158|M.gilvum_PYR-GCK TVYRIIGSKDELLMSIMLEFGRKVGGAWSDIVRTDSTTVEKLDALSWLNI
Mb3587c|M.bovis_AF2122/97 --------------------------------------------------
Rv3557c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_5283|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6009|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0599|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01070|M.leprae_Br4923 --------------------------------------------------
MMAR_4325|M.marinum_M NALDQFSDEFRIQLAWMRQSPPDTPNPGWLYAARLRQMKSLLSEGLRSAE
MUL_0135|M.ulcerans_Agy99 NALDQFSDEFRIQLAWMRQ-------------------------------
MAV_1265|M.avium_104 NALDQFSDEFRIQLAWMRLSPP-TANPGWSYATRLRQMKSLLSEGLRTGE
TH_3536|M.thermoresistible__bu NALDRFGDEFRIQLAWMRQSPPDTPNPGWLFAKRVRQVKSLLAAAIRSGE
Mflv_4158|M.gilvum_PYR-GCK NALDQFPDEFRIQLAWLRQSPPDSANPAWSFTTRIRQMKSLLSEGIRAGE
Mb3587c|M.bovis_AF2122/97 --------------------------------------------------
Rv3557c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_5283|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6009|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0599|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01070|M.leprae_Br4923 --------------------------------------------------
MMAR_4325|M.marinum_M IQIEPPSITMLARCVIGLQWIPENILHFVGTRAALIHARDTVLRGVAVRG
MUL_0135|M.ulcerans_Agy99 --------------------------------------------------
MAV_1265|M.avium_104 IAIAAPSTAMLARCLIALQWIPENILAEIGKRPALLHVRDTVLRGVAVRG
TH_3536|M.thermoresistible__bu ISIDSPSNELLARSVIGVGWVPENILRQIGTRAAQILVRDTVLRGAADRD
Mflv_4158|M.gilvum_PYR-GCK IHIDSPTADMLARCIIGEQWIPENILQEVGPRNALILARDTILRGVAVRT
Mb3587c|M.bovis_AF2122/97 --------------------------------------------------
Rv3557c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_5283|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6009|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0599|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01070|M.leprae_Br4923 --------------------------------------------------
MMAR_4325|M.marinum_M Q----
MUL_0135|M.ulcerans_Agy99 -----
MAV_1265|M.avium_104 AAVDN
TH_3536|M.thermoresistible__bu VTR--
Mflv_4158|M.gilvum_PYR-GCK -----
Mb3587c|M.bovis_AF2122/97 -----
Rv3557c|M.tuberculosis_H37Rv -----
Mvan_5283|M.vanbaalenii_PYR-1 -----
MSMEG_6009|M.smegmatis_MC2_155 -----
MAB_0599|M.abscessus_ATCC_1997 -----
MLBr_01070|M.leprae_Br4923 -----