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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3498 | - | - | 100% (271) | enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_2728 | - | 1e-28 | 32.10% (243) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_1273 | - | 1e-21 | 31.15% (244) | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0464c | echA2 | 6e-29 | 27.82% (266) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2433 | - | 2e-27 | 32.13% (249) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv0456c | echA2 | 6e-29 | 27.82% (266) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01241 | - | 2e-19 | 28.21% (234) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0836c | - | 8e-21 | 29.52% (227) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_0778 | echA2 | 9e-28 | 26.69% (266) | enoyl-CoA hydratase EchA2 |
| M. avium 104 | MAV_1848 | - | 8e-91 | 60.22% (269) | enoyl-CoA hydratase/isomerase |
| M. smegmatis MC2 155 | MSMEG_4846 | - | 2e-27 | 33.61% (244) | enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_1414 | echA2 | 6e-28 | 26.69% (266) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4219 | - | 3e-27 | 32.10% (243) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3498|M.thermoresistible__bu ---------------LETRTLEHVIYEKDGPIARIILNNPDRANAQTSEM
MAV_1848|M.avium_104 -------------MAAHSRDLGVVRYERDGAIARIVLDWPERANAQSSEM
Mb0464c|M.bovis_AF2122/97 ---------------MPTPDFQTLLYTTAGPVATITLNRPEQLNTIVPPM
Rv0456c|M.tuberculosis_H37Rv ---------------MPTPDFQTLLYTTAGPVATITLNRPEQLNTIVPPM
MMAR_0778|M.marinum_M ---------------MPTPEFQTLLYSTAGPVATITLNRPEHLNTIVPPM
MUL_1414|M.ulcerans_Agy99 ---------------MPTPEFQTLLYSTAGPVATITLNRPEHLNTIVPPM
Mflv_2433|M.gilvum_PYR-GCK ---------------------MYIDYEVSDRIATITLNRPEAANAQNPEL
Mvan_4219|M.vanbaalenii_PYR-1 ---------------------MYIDYDVTDRIATITLNRPEAANAQNPEL
MSMEG_4846|M.smegmatis_MC2_155 ---------------------MYIDYGVADSIATITLNRPEAANAQNPEL
MLBr_01241|M.leprae_Br4923 MSQTDASCTIAELPYRSVTDLVVLDFPRPE-VALITLNRPGRMNSMALDL
MAB_0836c|M.abscessus_ATCC_199 -----------------MSAARELLVERDGPVVILTMNRPHRRNALSTNM
: :. : :: * *: :
TH_3498|M.thermoresistible__bu VHSVNTALDDAQYDYDIKVVIIKANGKGFCSGHIPD-GSYPEFKAEIEAS
MAV_1848|M.avium_104 VSQVDSCLDEARQDYGVKVVIVKGSGKGFCAGHVMAPDAYPEFADSQLHM
Mb0464c|M.bovis_AF2122/97 PDEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFG-GGFQHWGDAMMTD
Rv0456c|M.tuberculosis_H37Rv PDEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFG-GGFQHWGDAMMTD
MMAR_0778|M.marinum_M PDEIEAAVGLAERDQGIKVIVLRGAGRAFSGGYDFG-GGFQHWGETMMTD
MUL_1414|M.ulcerans_Agy99 PDEIEAAVGLAERDQGIKVIVLRGAGRAFSGGYDFG-GGFQHWGETMMTD
Mflv_2433|M.gilvum_PYR-GCK LDELDAAWTRAAEDNDVSVIVLRANGKHFSAGHDLR--GGGPVPDKITLE
Mvan_4219|M.vanbaalenii_PYR-1 LDELDAAWTRAAEDNEVSVIVLRANGKHFSAGHDLR--GGGPVPDKITLE
MSMEG_4846|M.smegmatis_MC2_155 LDELDAAWTRAAEDNEVKVIILRANGKHFSAGHDLR--GGGEVPEKISLE
MLBr_01241|M.leprae_Br4923 MKSLKQVLKRITYDHSVRVVVLTGAGRGFCSGADQKFTAPVPQVEGLTQP
MAB_0836c|M.abscessus_ATCC_199 VSQFAAAWDEIDHDDGIRAAILTGAGSAYCVGGDLS-DGWMVRDGSAPPL
.. * : . :: . * :. * .
TH_3498|M.thermoresistible__bu GKVWRSAAQLFLWP--------VLKLWEFPKPVIAQVHGYAIGGGTTWAL
MAV_1848|M.avium_104 GSNYQGSKELFLWP--------TLRYWEFPKPMIAQVHGYAIGGGTYWAL
Mb0464c|M.bovis_AF2122/97 GRWDPGKDFAMVTARETGPTQKFMAIWRASKPVIAQVHGWCVGGASDYAL
Rv0456c|M.tuberculosis_H37Rv GRWDPGKDFAMVTARETGPTQKFMAIWRASKPVIAQVHGWCVGGASDYAL
MMAR_0778|M.marinum_M GQWDPGKDFAMVTARETAPTQKFMAIWRASKPVIAQIHGWCVGGASDYAL
MUL_1414|M.ulcerans_Agy99 GQWDPGKDFAMVTARETAPTQKFMAIWRASKPVIAQIHGWCVGGASDYAL
Mflv_2433|M.gilvum_PYR-GCK FIIQHEAKRYLEYT---------LRWRNVPKPSIAAVQGRCISGGLLLCW
Mvan_4219|M.vanbaalenii_PYR-1 FIIAHEAKRYLEYT---------LRWRNVPKPSIAAVQGRCISGGLLLCW
MSMEG_4846|M.smegmatis_MC2_155 FIIQHEARRYLDYT---------LRWRNVPKPSIAAVQGRCISGGLLLCW
MLBr_01241|M.leprae_Br4923 VRALRAMELLEEVI---------LALRRLHQPVIAAINGPAIGGGLCLAL
MAB_0836c|M.abscessus_ATCC_199 DPATIGKGLLLSHT--------------LTKPLIAAVNGACLGGGCEMLQ
:* ** ::* .:.*.
TH_3498|M.thermoresistible__bu IPEITVCSEDAWFQMPLVPGFGLPGSETMFEPWVF-MNYKRAAEYLYTAQ
MAV_1848|M.avium_104 LPELTIASEDAYFQMPLVPGLGFAGGETMIEPWVF-MNYKRAAEYLYTAQ
Mb0464c|M.bovis_AF2122/97 CADIVIASEDAVIGTPYSR----MWGAYLTGMWLYRLSLAKVKWHSLTGR
Rv0456c|M.tuberculosis_H37Rv CADIVIASEDAVIGTPYSR----MWGAYLTGMWLYRLSLAKVKWHSLTGR
MMAR_0778|M.marinum_M CADIVIASDDAVIGTPYSR----MWGAYLSGMWLYRLSFAKAKWHSLTGR
MUL_1414|M.ulcerans_Agy99 CADIVIASDDAVIGTPYSR----MWGAYLSGMWLYRLSFAKAKWHSLTGR
Mflv_2433|M.gilvum_PYR-GCK PCDLIVAADDAQFSDPVVLMG---IGGVEYHGHTWELGPRKAKEILFTGR
Mvan_4219|M.vanbaalenii_PYR-1 PCDLIVAADDAQFSDPVVLMG---IGGVEYHGHTWELGPRKAKEILFTGR
MSMEG_4846|M.smegmatis_MC2_155 PCDLILASDDALFSDPVALMG---IGGVEYHGHTWELGPRKAKEILFTGR
MLBr_01241|M.leprae_Br4923 AADVRVASTRAYFRAAGINNGLSASELGLSYLLPRAVGSSRAFEIMLSGR
MAB_0836c|M.abscessus_ATCC_199 QTDIRVSDEHATFGLPEVQRG-LVPGAGSMVRLKRQIPYTKAMEMILTGE
:: :. * : . : :. :..
TH_3498|M.thermoresistible__bu KITAQQALEFGLVNRVVPADELESTVEELAAKIAKAPLITLQATKAGILR
MAV_1848|M.avium_104 TLTAHEALRMGLVNRVVTRDELEPVTEALATKIARAPLSTLMATKTMLVR
Mb0464c|M.bovis_AF2122/97 PLTGVQAAEAELINEAVPFERLEARVAEIATELARIPLSQLQAQKLIVNQ
Rv0456c|M.tuberculosis_H37Rv PLTGVQAAEAELINEAVPFERLEARVAEIATELARIPLSQLQAQKLIVNQ
MMAR_0778|M.marinum_M PLSGVQAAQIELINEAVPFERLEARVAEVAAELAQIPLSQLQAQKLIVNQ
MUL_1414|M.ulcerans_Agy99 PLSGVQAAQIELINEAVPFERLEARVAEVAAELAQIPLSQLQAQKLIVNQ
Mflv_2433|M.gilvum_PYR-GCK AMTADEVAATGMVNKVVPRAELDAETRALAEQIAKMPPFALRQAKRAVNQ
Mvan_4219|M.vanbaalenii_PYR-1 AMTAEEVAATGMVNRVVPRDQLDAETRTLAEQIAKMPPFALRQAKRAVNQ
MSMEG_4846|M.smegmatis_MC2_155 ALTAEEAERTGMVNRVVARDELDAQTRELAEQIATMPPFALRQAKRAVNQ
MLBr_01241|M.leprae_Br4923 DVGAEEAEQIGLVSYRVSDDRLLDTCYSIAARMATFSRSGTELTKRALWG
MAB_0836c|M.abscessus_ATCC_199 PLTAFEAYHFGLVGHVVPAGTALDKARSLADRIVRNGPLAVRNAKEAIVR
: . :. ::. *. :* .:. * :
TH_3498|M.thermoresistible__bu AWETMGFRTHQQASNDLQAVVTGSREFQEYMAELMKRASKPADRV-----
MAV_1848|M.avium_104 AWEQMGMRQHLQLSADVMSVLENTSDAQALRAELVARGRLPRDQAGDG--
Mb0464c|M.bovis_AF2122/97 AYENMGLASTQLLGGILDGLMRNTPDALEFIRTAQTQGVRAAVERRDGPF
Rv0456c|M.tuberculosis_H37Rv AYENMGLASTQLLGGILDGLMRNTPDALEFIRTAQTQGVRAAVERRDGPF
MMAR_0778|M.marinum_M AYENMGLASTQTLGGILDGLMRNTPDALDFIKTAENQGVRAAVERRDGPF
MUL_1414|M.ulcerans_Agy99 AYENMGLASTQTLGGILDGLMRNTPDALDFIKTAENQGVRAAVERRDGPF
Mflv_2433|M.gilvum_PYR-GCK TLDVQGFYAAIQSVFDVHQTGHGNALSVGGWPVLVNLEEMKANIK-----
Mvan_4219|M.vanbaalenii_PYR-1 TLDVQGFYAAIQSVFDVHQTGHGNALSVGGWPVLVNLEEMKANIK-----
MSMEG_4846|M.smegmatis_MC2_155 TLDVQGFYAAIQSVFDIHQTGHGNALSVSGWPVLVDIEEMKANIK-----
MLBr_01241|M.leprae_Br4923 GLDAASLDKHMQSESLAQLFIALHTSNFEEAAAPCTEKRPTVLVDARGCA
MAB_0836c|M.abscessus_ATCC_199 S-GWLAEEDARAIEARLTRPVITSADAREGLAAFKEKREARFTGR-----
.
TH_3498|M.thermoresistible__bu ------------------------
MAV_1848|M.avium_104 ------------------------
Mb0464c|M.bovis_AF2122/97 GDYSQAPPELRPDPTHVITPDGSM
Rv0456c|M.tuberculosis_H37Rv GDYSQAPPELRPDPTHVITPDGSM
MMAR_0778|M.marinum_M GDYSQAPPELRPNPNHVIVPDRDR
MUL_1414|M.ulcerans_Agy99 GDYSQAPPELRPNPNHVIVPDRDR
Mflv_2433|M.gilvum_PYR-GCK ------------------------
Mvan_4219|M.vanbaalenii_PYR-1 ------------------------
MSMEG_4846|M.smegmatis_MC2_155 ------------------------
MLBr_01241|M.leprae_Br4923 TSPG--------------------
MAB_0836c|M.abscessus_ATCC_199 ------------------------