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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3227 | - | - | 100% (194) | 3-alpha-hydroxysteroid dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0874c | - | 8e-05 | 23.30% (176) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1565 | - | 3e-37 | 69.30% (114) | NAD-dependent epimerase/dehydratase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0248 | - | 1e-39 | 70.43% (115) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_5233 | - | 2e-43 | 73.91% (115) | 3-alpha-hydroxysteroid dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3704 | - | 2e-38 | 67.54% (114) | 3-alpha-hydroxysteroid dehydrogenase |
| M. ulcerans Agy99 | MUL_4865 | - | 4e-37 | 68.70% (115) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_5193 | - | 2e-40 | 57.93% (164) | NAD-dependent epimerase/dehydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1565|M.gilvum_PYR-GCK -----------------MGTYAITGSASGMGAAAVARLRADGHTVLTVDI
Mvan_5193|M.vanbaalenii_PYR-1 -----------------MGTYAITGSASGMGAAAVARLRADGHTVITVDI
MMAR_0248|M.marinum_M -----------------MGTYAITGSASGMGNATASRLREAGHRVIGVDL
MUL_4865|M.ulcerans_Agy99 -----------------MGTYAITGSASGMGNATASRLWEAGHRVIGVDL
MAV_5233|M.avium_104 -----------------MGTYAITGSASGMGRETAQRLRDGGHTVIGVDI
MSMEG_3704|M.smegmatis_MC2_155 MPQFLSTFSVGGCPGGIIGTYAVTGAASGMGYQAAQKLREQGHTVIGVDL
TH_3227|M.thermoresistible__bu -----------------------------MGRAAAEKLRAAGHRVIGVDL
Mb0874c|M.bovis_AF2122/97 ------------MDGFPGRGAVITGGASGIGLATGTEFARRGARVVLGDV
:* : .: * *: *:
Mflv_1565|M.gilvum_PYR-GCK KDADVVADLSTADGRADAAAQVLAACAGRLDGAVLAAGLGPSQGAERLRL
Mvan_5193|M.vanbaalenii_PYR-1 KDADVVADLSTSDGRAAAAAQVLTACDGRLDGAVLAAGLGPSQGAERLRM
MMAR_0248|M.marinum_M DGADVVADLSTQQGRLRAASDVIAACDGRLDGAVLAAGLGPSPGPGRLHR
MUL_4865|M.ulcerans_Agy99 DGADVVADLSTQQGRLRAASDVIAACDGRLDGAVLAAGLGPSPGPGRLHR
MAV_5233|M.avium_104 KDADVIADLSTPAGRADAAARVLSQAGDRLDGAVLAAGLGPSPARDRVRQ
MSMEG_3704|M.smegmatis_MC2_155 KEGEVVSDLSTPEGRRRAADEVMRLSGGRLDGAVLAAGLGPGPGAERPRL
TH_3227|M.thermoresistible__bu KDAEVVADLSTPAGRAAAADQVLAAAESRLDGAVLAAGLGPRPGRDSARM
Mb0874c|M.bovis_AF2122/97 DKPGLRQAVNHLRAEGFDVHGVMCDVRHREEVTHLAD--------EAFRL
. : :. .. . *: * : : ** :
Mflv_1565|M.gilvum_PYR-GCK IGAVNYLGVVDLLTRWRPALAVAQNAKVVVVGSNSTTTTPAVPGRAVRAL
Mvan_5193|M.vanbaalenii_PYR-1 IATVNYLGVVELLERWRPALAAAANAKVVVIGSNSTTTTPAVPARAVRAL
MMAR_0248|M.marinum_M IAQVNYLGVVELLQAWRPALAAAERAKAVVIASNSTTTVPMVPRRSVRAL
MUL_4865|M.ulcerans_Agy99 IAQVNYLGVVELLQARRPALAAAERAKAVVIASNSTTTVPMVPRRSVRAL
MAV_5233|M.avium_104 IAAVNYFGVVELLQAWRPALAAAGNAKVVVVASNSATTMPTVPRRTVNAL
MSMEG_3704|M.smegmatis_MC2_155 IAEVNFLGVVELLEAWRPALAAADRAKVVVLSSNSTTTTPAVPARAIRAL
TH_3227|M.thermoresistible__bu IVQVNYFGVVELLQSWRPALAAAGNAKVVVIGSNSTTTIPLVPRX-----
Mb0874c|M.bovis_AF2122/97 LGHFDVVFSNAGIVVGGPIVEMTHDDWRWVIDVDLWGSIHTVEAFLPRLL
: .: . : * : : *: : : *
Mflv_1565|M.gilvum_PYR-GCK LAGDVDRAIRAVRLYGPGKPAMMYAASKIAVTRWARRTAVLPEWAGAGIR
Mvan_5193|M.vanbaalenii_PYR-1 LAGDVDKALRATRLYGPGRPAMVYAASKIAVTRWARRHAVRPEWAGAGIR
MMAR_0248|M.marinum_M LDHDADKAVRAVRLFGKAAPSLMYAASKIAVSHWVRRQAVLPEWAGSGVR
MUL_4865|M.ulcerans_Agy99 LDHDADKAVRAVRLFGRAAPSLMYGASKIAVSHWARRQAVLPEWAGSGVR
MAV_5233|M.avium_104 LAHDADKALRSVRLFGPAAPTMMYGASKLAVSRWVRRHAVLAEWAGSGVR
MSMEG_3704|M.smegmatis_MC2_155 LARDTDKAVRTVRVLGRAGTPIMYAASKIAVSRWVRRTAVSAAWAGAGIR
TH_3227|M.thermoresistible__bu --------XRLLTISG------ALGTGNILPS------PVRPPVSG----
Mb0874c|M.bovis_AF2122/97 EQGTGGHVVFTASFAGLVPNAGLGAYGVAKYGVVGLAETLAREVTADGIG
. * . . .: :.
Mflv_1565|M.gilvum_PYR-GCK LNVLAPGAVMTPLLQEQLDNKRQAKFVEKFPVPVGGYGEPDLLARWMCFM
Mvan_5193|M.vanbaalenii_PYR-1 LNVLAPGAVMTPLLQEQLDNKRQARFVERFPVPVGGYGQPEQLAEWMRFM
MMAR_0248|M.marinum_M LNALAPGAIMTPLLAEQLSDPTQAKAVRSFPIPIGGFGEVTHMADWICFM
MUL_4865|M.ulcerans_Agy99 LNALAPGAIMTPLLAEQLSVPTQAKAVRSFPIPVGGFGEVTHMADWICFM
MAV_5233|M.avium_104 LNALSPGAIMTPLLQEQLSTPRQARAVRSFPVPVGGFGDPGQLAEWMCFM
MSMEG_3704|M.smegmatis_MC2_155 LNALAPGAIMTPLLQSQLAEPLESKAVRAFPVPIGGFGDAGQLADWICFM
TH_3227|M.thermoresistible__bu ----------VPTVTWRIVGRRYAVHSRVHPGKACG--------------
Mb0874c|M.bovis_AF2122/97 VSVLCPMVVETNLVANSERIRGAACAQSSTTGSPGPLPLQDDNLGVDDIA
. : : .
Mflv_1565|M.gilvum_PYR-GCK LSDAADFVCGSVIFVDGGTDALFRGDDWPRPVPVRRIARYVKRFLGRR--
Mvan_5193|M.vanbaalenii_PYR-1 LSDAADFLCGSVIFVDGGTDSLFRRDDWPRPVPARRIIGYVQRFRGRG--
MMAR_0248|M.marinum_M LSDSADFLCGSVVFVDGGSDAYFRADDWPRSVPARRLPGYLLSFRRGSRS
MUL_4865|M.ulcerans_Agy99 LSDSADFLCGSVVFVDGGSDAYFRADDWPRPVPARRLPGYLLKFRRGTRT
MAV_5233|M.avium_104 LSDAADFLCGSVVFVDGGTDAYFRADDWPKVLPARRLPGYLRRFTR----
MSMEG_3704|M.smegmatis_MC2_155 LSDSADFLCGSVVFVDGGSDAYFRATSWPRAVPVRGLAQYLWRFKRGAGR
TH_3227|M.thermoresistible__bu -------------------QFKMRSSPWHRTRSG-GLRGYRRSSR-----
Mb0874c|M.bovis_AF2122/97 QLTADAILAN---------RLYVLPHAASRASIRRRFERIDRTFDEQAAE
. : :
Mflv_1565|M.gilvum_PYR-GCK ----
Mvan_5193|M.vanbaalenii_PYR-1 ----
MMAR_0248|M.marinum_M NIR-
MUL_4865|M.ulcerans_Agy99 TVR-
MAV_5233|M.avium_104 -FR-
MSMEG_3704|M.smegmatis_MC2_155 ----
TH_3227|M.thermoresistible__bu ----
Mb0874c|M.bovis_AF2122/97 GWRH