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M. vanbaalenii PYR-1 Mvan_3845 (-)

annotation: amino acid adenylation domain-containing protein
coordinates: 4099381 - 4104546
length: 1721

TDIDTGALLDERRLELLRRRMQERGLSAGTDTAEPAGDTDVLTEGQLRMWFVHNADPSGALLNVCLSYRL
SGEIDVARLHDAVGAVARRHRVLRTTYRTESTAAGDSGMPVPTVHTGLMPGWAEHDLSELSERARGLRLE
VLAQREFGRPFDLGAESPLRITVIRTAPAEYVMLLVAHHIAWDDASWEVFFDDLTGAYVGEKLRPARRPV
VAAGGSDEDDVAYWRAVMADPPEPLELPGPTGSAVPTSWRSQRTTLRLDGETARRVTALADEVGATPYAV
LLAVFGVLIHRYSHVDDFLVATPVLNRNGDTDDVIGYFGNTVAMRLRPHPAMTFRDLLTQTRDTALGAFA
HQRVGLDRMVRELNPDRRHGAERMTRVSFGFRSRDRFGFTPPGVTCERADLRSHLTHLPLGIMVEFDPDE
VVVELEHLVEIIEPGLARQLLDHYAVLIRSALDDPDTTLSGLQLMGDDDLEWLRAVSVGPTFDTPPATIT
DLIEAQVRRSPDGTAVVYEGRHYTYREINEAANRVAHWLIGEDVGAEDRVAVMLDKSPELVVTALGVLKA
GAVYVPIDPAYPQDRLEFILGDCDAKVVVREPVTGLDGYRADDPGDNDRRRPVGPYNTAYLIYTSGSTGL
PKGVPVPHRPVAEYFVWFKGDYRVDAGDRMLQVASPSFDISIAEVFGTLACGARLVIHRPGGLNDIGYLT
ALLRDEGITAMHFVPSLLGLFLSLPGVNQWRTLQRVPIGGEALPGEVADKFRATFDALLHNFYGPTETVI
NATRFKVEGRQGTRIVPIGKPKINTAIHILDDALQPVPVGSIGEIYIGGTHVARGYHHRPGLTAERFVAD
PFTPGARMYRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAAITVDPSVGQAVVVVSDLPNLGK
SLVAYLTPADGAGVDVDRIRTRVAAALPEYMTPAAYVVVDEIPITAHGKIDRAALPEPEIAPTTEFREPA
AGTEAHLAQLFAELLGHEKVGADDSFFDLGGHSLLATKLVAELRAGFGVDVEVRDIFENATIARLAAHLD
TMGRATIGTRRPRLVAAPLDGPAPLSSSQLRSWFGYRIEGRSPVNNIPFAARLTGPCDVDAFVAAIRDVV
ERHAILRTTYREIDGVPYQIVNPISDVPVRRARGEGEQWLQAELDRERKHTFDLEEDWPIRAAVFTVGAV
SPASDGGAVSPASDGGAVDPASDHVLSVVIHHIAGDHWSGGVLFTDLVAAYRARKAGERPTWAPLPVQYT
DYGAWQAELLSDDTGIAGPQREYWIRQLADAPVESGLPLEFSRPRLPSGKGDAVEFTIDGQVRRQITELC
RELGITEFMLLQAAVAVTLAKVGGGLDIPLGTPVAGRSEAELEQLVGFFVNFVVLRNDLRGNPTLREVLI
RAREMALSAYSNQDVPFEQVVEAVNPPRTLARNPLFQVVVHVREQLPQRQMIDTDTEFTALEPTFDIAQA
DLSLNFLADGTGYRGYLIYRPELYARRTIERLGRWLPRVVAAFVDTPDRALGDVDIVSAEERQRVSQEWS
TGARVQVLDADLAPAPVGVFGDLYLSGGPFAQRHRTGDRARWDDDGRLEIAARAPGATVVEVAPPAVEFE
EPRTDSERALAALLSELLATEEVGRHDDFFGLGGDSVLAVQLAARARDTGLDLTARMVFEHPRLAELAAA
LDSGAGAAAEQPDTHHAPMSVSGLSEDELAALTASWGTGE*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_3845--100% (1721)amino acid adenylation domain-containing protein
M. vanbaalenii PYR-1Mvan_1000-e-14828.44% (1505) amino acid adenylation domain-containing protein
M. vanbaalenii PYR-1Mvan_3844-2e-9728.43% (1379) amino acid adenylation domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2401cmbtE0.066.69% (1711) peptide synthetase MBTE (peptide synthase)
M. gilvum PYR-GCKMflv_2696-0.061.47% (1801) amino acid adenylation domain-containing protein
M. tuberculosis H37RvRv2380cmbtE0.066.69% (1711) peptide synthetase MBTE (peptide synthase)
M. leprae Br4923MLBr_01996nrp3e-2627.42% (445) putative peptide synthase
M. abscessus ATCC 19977MAB_2122-0.040.78% (1758) putative peptide synthetase MbtE
M. marinum MMMAR_3691mbtE0.041.13% (1758) non-ribosomal peptide synthetase MbtE
M. avium 104MAV_2013-0.062.46% (1569) linear gramicidin synthetase subunit D
M. smegmatis MC2 155MSMEG_4511-0.062.17% (1734) linear gramicidin synthetase subunit B
M. thermoresistible (build 8)TH_3141-0.068.16% (1784) PUTATIVE amino acid adenylation domain
M. ulcerans Agy99MUL_3634mbtE0.041.18% (1758) non-ribosomal peptide synthetase MbtE

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_3845|M.vanbaalenii_PYR-1       ---MTDIDTGALLDERRLELLRRRMQERGLSAG---TDTAEPAG-DTDVL
TH_3141|M.thermoresistible__bu      VTDTTETRPAGADDEARLALLRRRLSERGLSAQ---QTTGAAS---EDRL
Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      MTDIADTATAS-TVEARLELMRRKLAERGLAAGRAAAEGSAAAV-DPTVL
Mflv_2696|M.gilvum_PYR-GCK          -------MTDTDLDARRLELLRRRLAGSGLREQDPAEPVAVAADPARGEF
MAV_2013|M.avium_104                --MTETTGAGTRLDDERLELLRRKLAERGLSRS------AGTARHDEPRM
MMAR_3691|M.marinum_M               -----MADDVRTLQDRRRELLRRRIAESGLAAEQSSDQPGICPG-ERYRL
MUL_3634|M.ulcerans_Agy99           -----MADDVRTLQDRRRELLRRRIAESGLAAEQSSDQPRICPG-ERYRL
MAB_2122|M.abscessus_ATCC_1997      -----MTGDQLSALDRRRELLRRRLAESGVAAQAVESAPRVQAG-ERRGL
MLBr_01996|M.leprae_Br4923          ------------------------------------MTAPNTRRVDRVPL
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       TEGQLRMWFVHNADPSGALLNVCLSYRLSGEIDVARLHDAVGAVARRHRV
TH_3141|M.thermoresistible__bu      SDGQLRMWFVHQADPSGALLNICLSYRISGPVDLAALRGALDAVARRHPV
Mb2401c|M.bovis_AF2122/97           ------MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHRI
Rv2380c|M.tuberculosis_H37Rv        ------MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHRI
MSMEG_4511|M.smegmatis_MC2_155      SDGQRRMWFVQGFDPSGVLLNVSLSYRLTGDIDAERMQAAVEAVARRHPI
Mflv_2696|M.gilvum_PYR-GCK          TDGQKRMWFVHSVDPSGVLLNVCLSYRISGEVDLARLHDAVTAVARRHPV
MAV_2013|M.avium_104                SVGQHRMWFVQSVDPDSALLNICVSYRLTGGVDTGRLHRAVDAVAARHPV
MMAR_3691|M.marinum_M               SDGQRRMWFLQTMDPDDVTLNICVAYRLAGLVDEDRLHTAVNDVVARHAI
MUL_3634|M.ulcerans_Agy99           SDGQRRMWFLQTMDPDDVTLNICVAYRLTGLVDEDRLHTAVNDVVARHAI
MAB_2122|M.abscessus_ATCC_1997      APGQRRMWFMQTKDPADTSLNICVAHRMRGALDQTRLRDAVAAVIRRHDV
MLBr_01996|M.leprae_Br4923          SRSQQNIYNGMLQDNDPALYFIGKSYRFH-QLELSVFLAALEATILKNPG
                                          ::     *   .   :  ::*:   ::   :  *:  .  ::  

Mvan_3845|M.vanbaalenii_PYR-1       LRTTYRTESTAAGDSGMPVPTVHTGLMPGWAEHDLSELS---ERARGLRL
TH_3141|M.thermoresistible__bu      LRTTY-----AADENGEPRPTVHAELRPGWTEHDLTDLADQSEQARRLRL
Mb2401c|M.bovis_AF2122/97           LRTTY-----PVGDDGVAQPTVHADLRPGWTQYDLTDLS---QRAQRLRL
Rv2380c|M.tuberculosis_H37Rv        LRTTY-----PVGDDGVAQPTVHADLRPGWTQYDLTDLS---QRAQRLRL
MSMEG_4511|M.smegmatis_MC2_155      LRTTF-----HADENGEPRAEVHDDLTPSWTTHDLSEKS---ERARKLRL
Mflv_2696|M.gilvum_PYR-GCK          LRTTF-----AADEAGEPQRTVHDDLLPGWTVQDISELS---EHARRLRL
MAV_2013|M.avium_104                LHTTY-----DTTDEGDPRPVLRADLRPEWAEHDLSGLT---EQARRLRL
MMAR_3691|M.marinum_M               LRTTY-----GVDTEGEPYQVFSDDVEVGWRREDLTRLP---EAGHERQI
MUL_3634|M.ulcerans_Agy99           LRTTY-----GVDTEGEPYQVFSDDVEVGWRREDLTRLP---EAGHEQQI
MAB_2122|M.abscessus_ATCC_1997      LRTVY-----GVDSAGEPYQLFVEEFEVPWTAVDLTDLT---GDAQDRQV
MLBr_01996|M.leprae_Br4923          QLCVL---------EAPSTEGDYPDLVPRLQFGDIVRVR--SDEQPQTDS
                                       .           . .       .       *:               

Mvan_3845|M.vanbaalenii_PYR-1       EVLAQREFGRPFDLGAESPLRITVIRTAPAEYVMLLVAHHIAWDDASWEV
TH_3141|M.thermoresistible__bu      EVLAQREFTAPFDLSVDSPLRITMIRTGADEHIMLLVAHHIAWDDGSWEV
Mb2401c|M.bovis_AF2122/97           EVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDDGSWRV
Rv2380c|M.tuberculosis_H37Rv        EVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDDGSWRV
MSMEG_4511|M.smegmatis_MC2_155      EVLAQREFGTPFDLGTESPLRLTLIRTGPAEHVLLLVAHHIAWDDGSWRV
Mflv_2696|M.gilvum_PYR-GCK          EVLAQREFGTPFDLATESPLRITVARTAPAEYIMLLVVHHIAWDDGCWRV
MAV_2013|M.avium_104                DVLAQRDFRRPFDLSKDSPLRVTAARLADDELMLLITAHHIAWDDGSWAP
MMAR_3691|M.marinum_M               ESLAADEFGRPFDLTNELPLRITVIRTRADELVLLLVVHHICWDDDSWEV
MUL_3634|M.ulcerans_Agy99           ESLAADEFGRPFDLTNELPLRITVIRTRADELVLLLVVHHICWDDDSWEV
MAB_2122|M.abscessus_ATCC_1997      RALADSEFGRPFDLAADRPLRVTLLRLGAEDFVVLLVVHHICWDDNSWEV
MLBr_01996|M.leprae_Br4923          RDYDLMHAWSPDILAKPLVRYTVRTDKNGFVARLDVFTHHILVDGGAIRI
                                          .   *  *        .          : : .***  *. .   

Mvan_3845|M.vanbaalenii_PYR-1       FFDDLTGAYV----------GEKLRPARRPVVAAGGSD-EDDVAYWRAVM
TH_3141|M.thermoresistible__bu      FFDDLTRAYT----------GVDLGEELAPQLPPGPRDPDADLAYWREVL
Mb2401c|M.bovis_AF2122/97           FFTDLTQAYSRA-----DL-GADLGPEHRPSAASGPDTTEADLNYWRAIM
Rv2380c|M.tuberculosis_H37Rv        FFTDLTQAYSRA-----DL-GADLGPEHRPSAASGPDTTEADLNYWRAIM
MSMEG_4511|M.smegmatis_MC2_155      FFTDLTRAYS----------GEQLPETPR-VGAAAPDTTDEDLAYWREVM
Mflv_2696|M.gilvum_PYR-GCK          FFADLTRAYT----------GAELGPTPAPVVEP--PTSDEDLRFWRSAM
MAV_2013|M.avium_104                FFADLTRAYTAP-----G--DFDATPVVPDLSADPTAIRREDLDYWRPLM
MMAR_3691|M.marinum_M               FFGELSAAYNDL-----PINDPAAQFLSVEVLQNSAAPSVADVGYWAETL
MUL_3634|M.ulcerans_Agy99           FFGELSAAYNDL-----PINDPAAQFLSVEVLQNSAAPSVADVGYWAETL
MAB_2122|M.abscessus_ATCC_1997      FFAELSEYYHGR-----PVQGEAPQFMVVS--ADTEPSSDADLTYWRRAL
MLBr_01996|M.leprae_Br4923          IEENLAHHLDTDNRLEIPCIRQALDKLAEAHRREATKVEESLQRLANVVQ
                                    :  :*:                                            

Mvan_3845|M.vanbaalenii_PYR-1       ADPPEPLELPGPTGSAVPTSWRSQR----TTLRLDGETARRVTALADEVG
TH_3141|M.thermoresistible__bu      ADPPEPLELPGPHGSAVPSGWRSAR----DSVTLGADTARRVVELAQETG
Mb2401c|M.bovis_AF2122/97           ADPPEPLELPGPAGTCVPTSWRAAR----ATLRLPADTAARVATMAKNTG
Rv2380c|M.tuberculosis_H37Rv        ADPPEPLELPGPAGTCVPTSWRAAR----ATLRLPADTAARVATMAKNTG
MSMEG_4511|M.smegmatis_MC2_155      ANPPEPLELPGPMGSVVPTGFRSQR----STVRLSAETVEKVTVLARETG
Mflv_2696|M.gilvum_PYR-GCK          TDLPEPLELPGPHGSAVPTTWRCRR----VTATLSADTVERVRVAAREAG
MAV_2013|M.avium_104                ADLPEPLELPGPNGSVVPSTWRAQR----AFAELPAEIVDRAAALARETG
MMAR_3691|M.marinum_M               RPLPEPPELPGVSG--ANPCRRAQR----RVRPLPAGLFSRVEDFARKCS
MUL_3634|M.ulcerans_Agy99           RPLPEPPELPGVSG--ANPCRRAQR----RVRPLPAGLFSRVEEFARKCS
MAB_2122|M.abscessus_ATCC_1997      TPLPDPLELPGAAS--TYSSRAARR----LAVPMPAETAARIEEFAREHS
MLBr_01996|M.leprae_Br4923          RELADEVRNGGYGQVSNDAPGNAARGVLHESMIICGKAFDNIIALSETKQ
                                       .:  .  *       .   . *        : .    .    :    

Mvan_3845|M.vanbaalenii_PYR-1       ATPYAVLLAVFGVLIHRYSHVDDFLVATPVLNRNGDTDDVIG-YFGNTVA
TH_3141|M.thermoresistible__bu      CTPYAVLLAVFGTLIFRYTHADDFLVATPVLNRDSGAEQRIG-YYGNTVA
Mb2401c|M.bovis_AF2122/97           CTPYMVLLAAFGALVHRYTHSDDFLVAAPVLNRGAGTEDAIG-YFGNTVA
Rv2380c|M.tuberculosis_H37Rv        CTPYMVLLAAFGALVHRYTHSDDFLVAAPVLNRGAGTEDAIG-YFGNTVA
MSMEG_4511|M.smegmatis_MC2_155      ATPYMVLLAAFGALIRRYTHTDDFLVATPVLNR--DTEDTIG-YHGNTVA
Mflv_2696|M.gilvum_PYR-GCK          ATPYMVMLAAFGALLHRYTHADDVLIASPVLLRGPDSEDVIG-YHGNSAV
MAV_2013|M.avium_104                ATPYMVLMAAFAALVHRYTGSTDFLVAAPVLNRGAATENVIG-YYGNTVV
MMAR_3691|M.marinum_M               ASPFMVLLAAYGVLVRRYTGASDFLVSVPVTERSGAAAGALG-YFGNTLL
MUL_3634|M.ulcerans_Agy99           ASPFMVLLAAYGVLVRRYTGASDFLVSVPVTERSGAAAGALG-YFGNTLL
MAB_2122|M.abscessus_ATCC_1997      ATPFMVLLAAFGVLVHRYTGSRDFVTAIPVAERKSNAEKAIG-YFGNTLL
MLBr_01996|M.leprae_Br4923          VPLNILVATAAVAVDASLRQSTEGLLVHAVDNRFGDPYLDVATCLVNSVA
                                     .   :: :.  .:        : :   .*  *   .   :.    *:  

Mvan_3845|M.vanbaalenii_PYR-1       MRLRPHPAMTFRDLLTQTRDTALGAFAHQRVGLDRMVRELNPDR---RHG
TH_3141|M.thermoresistible__bu      MRLRPNAAMSFRDMLAQSRDTALGAFAHQGINLDRVVRELNPDR---RHG
Mb2401c|M.bovis_AF2122/97           MRLRPQSAMSFRELLTATRDIASGAFAHQRINLDRVVRELNPDR---RHG
Rv2380c|M.tuberculosis_H37Rv        MRLRPQSAMSFRELLTATRDIASGAFAHQRINLDRVVRELNPDR---RHG
MSMEG_4511|M.smegmatis_MC2_155      MRMRPRSDAGFRDLVLQTRDVALGAFAHQRVNLDRVVRELNPDR---RHG
Mflv_2696|M.gilvum_PYR-GCK          MRLRPQPMQTFTELLSRTRDFALDAFAHQQVNLDRVVRELNLDR---RHG
MAV_2013|M.avium_104                IRLRPQSHQSFRELLAQTRDGAVGAFAHSRADLDWLVRESNPDR---RHG
MMAR_3691|M.marinum_M               LRITTRSQDTFTSFVNEVRETCLAGFAHQSVGIDRVVREANPER-MGRDG
MUL_3634|M.ulcerans_Agy99           LRITTRSQDTFTSFVNEVRETCLAGFAHQSVGIDRVVREANPER-MGRDG
MAB_2122|M.abscessus_ATCC_1997      LRTVVNPDDSFASHVAAVREVCLDAFGHQNVGIDEVVREVNPSRSIGHDG
MLBr_01996|M.leprae_Br4923          HSIRFPPFASVQDVVRTLDRSYVKAIRLRWLREEYYRRIYLALN----QT
                                          .   . . :         .:       :   *     .    . 

Mvan_3845|M.vanbaalenii_PYR-1       AERMTRVSFGFRSRDRFGFTPPGVTCERADLRSHLTHLPLGIMVEFDPD-
TH_3141|M.thermoresistible__bu      TERMTRVSFGFRGPDRFGFTPPGVRCERAELRSHLTQLPLGVMIEFDPDP
Mb2401c|M.bovis_AF2122/97           AERMTRVSFGFREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDRA-
Rv2380c|M.tuberculosis_H37Rv        AERMTRVSFGFREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDRA-
MSMEG_4511|M.smegmatis_MC2_155      AERMTRVSFGFREPDGGGFCPAGVRCERAELRGNHTQLPLGFMVEWEAT-
Mflv_2696|M.gilvum_PYR-GCK          AERMTRVSFGFREPDGGGFSPPGVTCRRAELRGQITQLPLGLMVELHES-
MAV_2013|M.avium_104                ADRMTRVSFGQREPDGAGFCPPGVRCERGDLRGHFNQLPLSLMVELNRTP
MMAR_3691|M.marinum_M               MDLLVRLGFNMR-KSAGGLALDGVVVRQLGLGAVAAHLPLSLTIALDPD-
MUL_3634|M.ulcerans_Agy99           MDLLVRLGFNMR-KSAGGLALDGVVVRQLGLGAIAAHLPLSLTIALDPD-
MAB_2122|M.abscessus_ATCC_1997      MDELVRLGFSMR-KDASGYRLEGVDVTQLDLAAVSAQLPLSLAIATESS-
MLBr_01996|M.leprae_Br4923          SHIEALTLNFIREPCAPGLRPFLSEVPTVTDIGPVEGMTVACVLNEDER-
                                     .  .      *     *              .    :.:.  :  .   

Mvan_3845|M.vanbaalenii_PYR-1       ----EVVVELEHLVEIIEPGLARQLLDHYAVLIRSALDDPDTTLSGLQLM
TH_3141|M.thermoresistible__bu      ADP-GATVEIEHLVEVIEPALGRQLLRHFVVLLEDALRRPDTPLSRLRLM
Mb2401c|M.bovis_AF2122/97           ----GVLVEAEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALM
Rv2380c|M.tuberculosis_H37Rv        ----GVLVEAEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALM
MSMEG_4511|M.smegmatis_MC2_155      ----GATVEAEHLTEVLDAALAEQMLRHFTVLLDNALADPDRALWRLDLF
Mflv_2696|M.gilvum_PYR-GCK          ----GAVVEAEFLVEVLDDTLVTQMLDHYVVLLEAAVAQPDTVLSRLELM
MAV_2013|M.avium_104                DGSGGGLVEAEYLVEVLDQQLVEQMLRHYRTLLDSLLSDPDATLSACALM
MMAR_3691|M.marinum_M               ----DVSVEFEYQQQLS-SVLVDQMLVHYLQLVDKALAEPERPLSSLDIL
MUL_3634|M.ulcerans_Agy99           ----DVSVEFEYQQQLS-SVLVDQMLAHYLQLVDKALAEPERPLSSLDIL
MAB_2122|M.abscessus_ATCC_1997      ----GTIVEFEYQTDVLPQWLVGQLLVHYQRLLADGLSRPEETLARLELF
MLBr_01996|M.leprae_Br4923          ----TLDLSIWNRVDLPQGKSCTRVAKRIAAALELMAAAWDQPIAMIVN-
                                           :.     ::       ::  :    :       :  :      

Mvan_3845|M.vanbaalenii_PYR-1       GDDDLEWLRAVSVGPTFDTPPATITDLIEAQVRRS--PDGTAVVYEGRHY
TH_3141|M.thermoresistible__bu      DDADLAWLRDVSRGDRFDTPARTLPDLIESQVRQT--PDAVAVVYEGRHY
Mb2401c|M.bovis_AF2122/97           DERDAARLREVSRGERFDTPVKTLVDLVNEQTTRT--PDATAVVYEGQHF
Rv2380c|M.tuberculosis_H37Rv        DERDAARLREVSRGERFDTPVKTLVDLVNEQTTRT--PDATAVVYEGQHF
MSMEG_4511|M.smegmatis_MC2_155      TAEDTAWLTRMATGEAFDTPAATLTDLVTQQAERT--PDATAVVYEGRHF
Mflv_2696|M.gilvum_PYR-GCK          DGDDAEWLRRVSHGPEFDVPAATIGELIEARTDLT--PDTVAVVYEGRRY
MAV_2013|M.avium_104                SDADAEWLRAVSTGEQFITPAATLSELVSRRAART--PDAVAVVYEGRTY
MMAR_3691|M.marinum_M               GAGERDSVLAQSHGELVEMPATTMVKLLEATASAAGTATALALVSDEAEL
MUL_3634|M.ulcerans_Agy99           GAGERDSVLAQSHGELVEMPATTMVKLLEATASAAGTATALALVSDEAEL
MAB_2122|M.abscessus_ATCC_1997      DAEEHSALLDQSHGVLTRPSAATLVDLLDAAARAT--PEALAVVSDDVEL
MLBr_01996|M.leprae_Br4923          -----EWFGISSDGALCLGNEVTQTTRPLAPAWFLDPGGSVHLTVDKRRY
                                           .   : *        *        .          :. :    

Mvan_3845|M.vanbaalenii_PYR-1       TYREINEAANRVAHWLIGEDVGAEDRVAVMLDKSPELVVTALGVLKAGAV
TH_3141|M.thermoresistible__bu      SYRELNEAANRVAHWLIGQGIGTEDRVAVLLDKSPELVITALGVLKAGAV
Mb2401c|M.bovis_AF2122/97           TYHDLNEASNRLGHWLIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAV
Rv2380c|M.tuberculosis_H37Rv        TYHDLNEASNRLGHWLIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAV
MSMEG_4511|M.smegmatis_MC2_155      TYREINESANRLAHWLIGQGIGTEDRVAVLLEKSPELVITALGIVKAGAV
Mflv_2696|M.gilvum_PYR-GCK          TYREINESANRVAHWLIGQGIGAEDRVAVLMDRSPELLITALGIIKAGAV
MAV_2013|M.avium_104                TYRDIEEESNRVAHWLIERGVGTEDRVAVLLDKSPELVITALGVLKAGGV
MMAR_3691|M.marinum_M               TYSELHRRANRLARWFIGQGFGPEDIIGLRMANSIEFIVAMLAVLKAGAA
MUL_3634|M.ulcerans_Agy99           TYSELHRRANRLARWFIGQGFGPEDIIGLRMANSIEFIVAMLAVLKAGAA
MAB_2122|M.abscessus_ATCC_1997      TYELLQQRSNRFARWLVAQGAGTEDVIALQMSTSVEFIVAMLGVLKSGAA
MLBr_01996|M.leprae_Br4923          VHPWIA--------WLVRGSVVPGDVLVFTDDNTDKTIDLLIACHLAGCG
                                     :  :         *::  .  . * : .    : . :   :.   :*  

Mvan_3845|M.vanbaalenii_PYR-1       YVPIDPAYPQDRLEFILGDCDAKVVVREPVTGLDGYRAD-----DPGDND
TH_3141|M.thermoresistible__bu      YLPIDPTYPDDRLSFILGDCDARLVLREPVSDLDGQPTT-----DPTDTD
Mb2401c|M.bovis_AF2122/97           YVPVDPSYPQDRLDFILADCDAKLVLRTPVRELAGYRSD-----DPTDAD
Rv2380c|M.tuberculosis_H37Rv        YVPVDPSYPQDRLDFILADCDAKLVLRTPVRELAGYRSD-----DPTDAD
MSMEG_4511|M.smegmatis_MC2_155      YLPVDPTYPEDRLNYILSDSDPKIVLREFVTGLDDQPTT-----DPTDAE
Mflv_2696|M.gilvum_PYR-GCK          YLPVDPSYPQDRMSFVLSDSDPTLVIREPVAGLDGHRTD-----NPTDDV
MAV_2013|M.avium_104                YLPVDPTYPQDRLNFILGDADAKLVLREPVTDLADYPAT-----APT--E
MMAR_3691|M.marinum_M               YLPIDPAYPDERIDYLITDARPQTVIGRPELDVAERAAADNSDLPLSDSD
MUL_3634|M.ulcerans_Agy99           YLPIDPAYPDERIDYLITDARPQTVIGRPELDVAERAAADNSDLPLSDGD
MAB_2122|M.abscessus_ATCC_1997      YMPIDPALPEERIEYLIADAKPRIVMRPQEFRVAEAAATGLGDAPITDAD
MLBr_01996|M.leprae_Br4923          YSVCDTVAEVPLRAKAITDHGGGVSARVIDVAATQLAVTPDNEQSKLADK
                                    *   *.          : *                               

Mvan_3845|M.vanbaalenii_PYR-1       RRRPVGP-----YNTAYLIYTSGSTGLPKGVPVPHRPVAEYFVWFKGDYR
TH_3141|M.thermoresistible__bu      RVRRLLP-----GNTAYLIYTSGTTGLPKGVPVPHRPVAEYFVWFKGDYQ
Mb2401c|M.bovis_AF2122/97           RIRPLRP-----DNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFKGEYD
Rv2380c|M.tuberculosis_H37Rv        RIRPLRP-----DNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFKGEYD
MSMEG_4511|M.smegmatis_MC2_155      RVRPLRP-----DNTAYLIYTSGSTGLPKGVPVPHRPIAEYFVWFGGEYD
Mflv_2696|M.gilvum_PYR-GCK          RVRPLRP-----ENAAYLIYTSGSTGQPKGVPVPHRPVAEYFVWFKDEYE
MAV_2013|M.avium_104                LLRPLTP-----QNTAYLIYTSGSTGLPKGVPVPHAPIAEYFVWFGDEYR
MMAR_3691|M.marinum_M               RLRPLRP-----GHLAYVIYTSGSTGRPKGVAVSHHAIAEHVQGFVAEWT
MUL_3634|M.ulcerans_Agy99           RLRPLRP-----GHLAYVIYTSGSTGRPKGVAVSHHAIAEHVQGFVAEWT
MAB_2122|M.abscessus_ATCC_1997      RLRPLLP-----DNLAYVIYTSGSTGRPKGVAVAHAAIAEHVVSFTAEWS
MLBr_01996|M.leprae_Br4923          LIKQAAQDISLADKTAYIMPTSGSTGQPKLVQVSHGSLALFCDAVRNAYG
                                      :          : **:: ***:** ** * *.* .:* .   .   : 

Mvan_3845|M.vanbaalenii_PYR-1       VDAGDRMLQVASPSFDISIAEVFGTLACGARLVIHRPGGLNDIGYLTALL
TH_3141|M.thermoresistible__bu      VDANDRLLQVASPSFDVSIAEIFGTLACGARLVIHRPGGLNDIGYLTALL
Mb2401c|M.bovis_AF2122/97           VDDTDRLLQVASPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALL
Rv2380c|M.tuberculosis_H37Rv        VDDTDRLLQVASPSFDVSIAEIFGTLACGARMVIPRPGGLTDIGYLTALL
MSMEG_4511|M.smegmatis_MC2_155      VTNEDRLLQVASQSFDVSIGEIFGMLAAGARLVIPKPGGLTDIGYLTDLL
Mflv_2696|M.gilvum_PYR-GCK          ISESDRLLQVASPSFDVSIGEIFGTLACGGRLVIPKPDGLTDVAYLTELL
MAV_2013|M.avium_104                IDETDRLLQVASPSFDVSIGEIFGTLIMGARLVIPRPDGLRDIGYLTELL
MMAR_3691|M.marinum_M               MTAEDRWLQFSSVSFDASLADIFVTLFLGAQLIVPKPDAFGDISYVADLI
MUL_3634|M.ulcerans_Agy99           MTAEDRWLQFSSVSFDASLADIFVTLFLGAQLIVPKPDAFGDISYVADLI
MAB_2122|M.abscessus_ATCC_1997      MTADDRMLQSTSVSFDASLADILCPLSLGAQLVIPKPNPFSDIGYVADLV
MLBr_01996|M.leprae_Br4923          WGAHDTILQCAPLTSDISVEEIFGGAICGSKLVRSTAMKTGDLAELARDI
                                        *  ** :. : * *: :::     *.:::   .    *:. ::  :

Mvan_3845|M.vanbaalenii_PYR-1       RDEGITAMHFVPSLLGLFLSLPGVNQWR---TLQRVPIGGEALPGEVADK
TH_3141|M.thermoresistible__bu      QDEGITAMHFVPSLLGLFLSLPGVNQWR---TLQRVPIGGEPLPGEVADK
Mb2401c|M.bovis_AF2122/97           RDEGITAMHFVPSLLGLFLSLPGVSQWR---TLQRVPIGGEPLPGEVADK
Rv2380c|M.tuberculosis_H37Rv        RDEGITAMHFVPSLLGLFLSLPGVSQWR---TLQRVPIGGEPLPGEVADK
MSMEG_4511|M.smegmatis_MC2_155      RNEGITSMHFVPSLLGLFLSLPGVNEWR---TLQRVPIGGEALPGEIADK
Mflv_2696|M.gilvum_PYR-GCK          QREGITAMHFVPSLLGLFLSLPGVNQWR---TLERVPIGGEALPGELADR
MAV_2013|M.avium_104                AREGITSMHFVPSLLGLFLSLPGVSQWR---TLRRVPIGGEALPGEIADK
MMAR_3691|M.marinum_M               SRRGVTVLHLVPSMLSTLLLLPQVQQWR---QLRHVPVGGEALPGEVADR
MUL_3634|M.ulcerans_Agy99           SRRGVTVLHLVPSMLSTLLLLPQVQQWR---QLRHVPVGGEALPGEVADR
MAB_2122|M.abscessus_ATCC_1997      RRRGVTVLHMVPSLLGSVLLLPEARELR---GLRHVPVGGEALPGEVADK
MLBr_01996|M.leprae_Br4923          FVQRATVIDLPTAVWHLLCDHSDAIDEINRSCLRQIVIGGEAVRPCAVDK
                                      .  * :.: .::   .   . . :      *.:: :***.:    .*:

Mvan_3845|M.vanbaalenii_PYR-1       FRAT---FDALLHNFYGPTETVINATRFKVEGRQGTRIVPIGKPKINTAI
TH_3141|M.thermoresistible__bu      FHAT---FDALLHNFYGPTETVINASRYKVEGKQGTRIVPIGRPKINTQL
Mb2401c|M.bovis_AF2122/97           FHAT---FDALLHNFYGPTETVINASRFKVVGPQGTRIVPIGRPKINTTM
Rv2380c|M.tuberculosis_H37Rv        FHAT---FDALLHNFYGPTETVINASRFKVVGPQGTRIVPIGRPKINTTM
MSMEG_4511|M.smegmatis_MC2_155      FHAT---FDSLLHNFYGPTETVLNCTRYKVEGKQGARTVPIGKPKINTTI
Mflv_2696|M.gilvum_PYR-GCK          FHAT---FDALLHNFYGPTETIINTTRYKVEGTQGSRIVPIGTPKINTTV
MAV_2013|M.avium_104                FHAT---FDASLYNFYGPTETVVNCTSYPVEGAQGTRVVPIGRPKINTRV
MMAR_3691|M.marinum_M               FAGY---FDAELRNHYGPTEAVVCSTHMVVTGSHGARVVPIGVPNRNVYA
MUL_3634|M.ulcerans_Agy99           FAGY---FDAELRNHYGPTEAVVCSTHMLVTGSHGARVVPIGVPNRNVYA
MAB_2122|M.abscessus_ATCC_1997      FATM---FDAELRNHYGPTEAVVCSTYMSVRGPQGNSIVPIGRPNQNVYA
MLBr_01996|M.leprae_Br4923          WIDSGASQGISLMSTYGPTETTVVVTYLPIVCAP-------MTVESDARL
                                    :       .  * . *****: :  :   :              : :.  

Mvan_3845|M.vanbaalenii_PYR-1       HILDDALQPVPVGSIGEIYIGGTHVARGYHHRPGLTAERFVADPFTPGAR
TH_3141|M.thermoresistible__bu      HLLDNALQPVPVGVIGEIYIGGTHVAHGYHRRPGLTAERFVADPFNPGGR
Mb2401c|M.bovis_AF2122/97           HLLDDSLQPVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSR
Rv2380c|M.tuberculosis_H37Rv        HLLDDSLQPVPTGVIGEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSR
MSMEG_4511|M.smegmatis_MC2_155      HLLDDALQPVPVGVIGEIYIGGTHVAHGYHRRPGMTAERFVADPFNPGGR
Mflv_2696|M.gilvum_PYR-GCK          HLLDDALRPVPVGAIGEIYIGGGHVARGYHRRPALTAERFVADPFTVGGR
MAV_2013|M.avium_104                YLLDNALQPVPPGVIGEIYIAGTHVAHGYHRRPQLTAERFVADPFSRGGR
MMAR_3691|M.marinum_M               YVLDEQLHPVPDQVIGELYLGGSQLARGYLGRPTLTAQRFIADPFNPGMR
MUL_3634|M.ulcerans_Agy99           YVLDEQLHPVPDQVVGELYLGGSQLARGYLGRPTLTAQRFIADPFNPGMR
MAB_2122|M.abscessus_ATCC_1997      YVLDQALKLVPAGVVGELYLGGAQLARGYRARPVLTAERFVADPFGSGGR
MLBr_01996|M.leprae_Br4923          RLGWPIVPNTVFIAFGELVIVGDLVSVGYLGIDSRNFG-TVTTTDGSCRR
                                     :    :  .    .**: : *  :: **      .    :: .     *

Mvan_3845|M.vanbaalenii_PYR-1       MYRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAAITVDPSVGQ
TH_3141|M.thermoresistible__bu      LYRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAAISVDPSVGQ
Mb2401c|M.bovis_AF2122/97           MYRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAAIAVDPTVGQ
Rv2380c|M.tuberculosis_H37Rv        MYRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAAIAVDPTVGQ
MSMEG_4511|M.smegmatis_MC2_155      MYRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGEVSAAISVDPSVGQ
Mflv_2696|M.gilvum_PYR-GCK          LYRSGDLARRNADGDLEFVGRADDQVKIRGFRIELGEVAAAISVDPSVGQ
MAV_2013|M.avium_104                MYRSGDLARRNANGDIEFVGRADEQVKIRGFRIELGEIAAAISVDPSVGQ
MMAR_3691|M.marinum_M               LYRTGDLVRRNHCGELEFVGRADEQVKIRGFRIELGEVESVITTHPAVRH
MUL_3634|M.ulcerans_Agy99           LYRTGDLVRRNHCGELEFVGRADEQVKIRGFRIELGEVESVITTHPAVRH
MAB_2122|M.abscessus_ATCC_1997      LYRTGDLVRRNARGELEFVGRADEQVKVRGYRIELGEIEAVIGADPRVGH
MLBr_01996|M.leprae_Br4923          AFATADCVILDDEGFPVFSGRKDAVVKISGKRVDTAELIRRISTDPNVSD
                                     : :.* .  :  *   * ** *  **: * *:: .::   * ..* * .

Mvan_3845|M.vanbaalenii_PYR-1       AVVVVSDLPNLGKSLVAYLTPADG------AGVDVDRIRTRVAAALPEYM
TH_3141|M.thermoresistible__bu      AVVVATDLPNVGRSLVGYLTPVSGE---STDSVAVERIRARVAAALPEYM
Mb2401c|M.bovis_AF2122/97           AVVVVSDLPRLGKSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYM
Rv2380c|M.tuberculosis_H37Rv        AVVVVSDLPRLGKSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYM
MSMEG_4511|M.smegmatis_MC2_155      AVVVVSDLPSLGKSLVAYITPAAG-----ADHVDIERIRARVTAALPEYM
Mflv_2696|M.gilvum_PYR-GCK          AVVLGQDLPGLGMSLVGYVTPAAG------EDVDLARVRERVAAALPDYM
MAV_2013|M.avium_104                AVVLAMDLPQLGKSLVGYVTPAQGAG---TETVDVERIRARVAAALPDYM
MMAR_3691|M.marinum_M               CLV-VAEETEAGPMLAAYLVPA-------AAQVDLEEIRAHTAAAVPEYM
MUL_3634|M.ulcerans_Agy99           CLV-VAEETEAGPMLAAYLVPA-------AAQVDLEEIRAHTAAAVPEYM
MAB_2122|M.abscessus_ATCC_1997      CVATVVDDPQVGSLLAAYVVPAGG-----TREIDLDELRARAQEALPAYM
MLBr_01996|M.leprae_Br4923          VAVEVYNG-RLGVWFETKLTREG---------VDDAAAATRSRLILASLG
                                      .   :    *  :   :.            :       :    :.   

Mvan_3845|M.vanbaalenii_PYR-1       TPAAYVV-VDEIPITAHGKIDR-AALPEPEIAPTTEFREPAAGTEAHLAQ
TH_3141|M.thermoresistible__bu      VPAAYVV-LDEIPITTHGKIDR-AALPEPQIASMIEYREPATDTEREVAR
Mb2401c|M.bovis_AF2122/97           LPAAYVV-LDEIPITAHGKIDR-AALPEPQIASDTEFRAPQTATERRLAQ
Rv2380c|M.tuberculosis_H37Rv        LPAAYVV-LDEIPITAHGKIDR-AALPEPQIASDTEFRAPQTATERRLAQ
MSMEG_4511|M.smegmatis_MC2_155      VPAAYVE-LDEIPITTHGKIDR-RALPEPEITSTTRFREPSTDTERTVAG
Mflv_2696|M.gilvum_PYR-GCK          TPAGYVV-LDEIPITAHGKIDR-AALPLPEITTATDYREPQTETEQHLAQ
MAV_2013|M.avium_104                TPAAYVV-LDEIPITAHQKIDR-AALPQPQIGAGTEYRDPTTPTEHRIAQ
MMAR_3691|M.marinum_M               VPGAFAV-IPEIPMTVSGKLDR-RALPAPTPIATRRYREPETATERWICS
MUL_3634|M.ulcerans_Agy99           VPGAFAV-IPEIPMTVSGKLDR-RALPAPTPIATRRYREPETATERWICS
MAB_2122|M.abscessus_ATCC_1997      VPTAFAV-IPEIPLTTSGKLDK-RALPTPDALTERAFRLPVTPTERRMCA
MLBr_01996|M.leprae_Br4923          VSSFFVVGVPCIPRKPNGKIDRDNLLVMPQLVDSVQNYAGSGEGAAGLAE
                                     .  :.  :  ** .   *:*:   *  *                  :. 

Mvan_3845|M.vanbaalenii_PYR-1       LFAELLG-HEKVGADDSFFDLGGHSLLATKLVAELRAGFGVDVEVRDIFE
TH_3141|M.thermoresistible__bu      LFGDLLGRSERIGADDSFFDLGGHSLLATKLVAAVRSAFGVDIGVQDVFE
Mb2401c|M.bovis_AF2122/97           LFGELLG-RDRVGADDSFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFE
Rv2380c|M.tuberculosis_H37Rv        LFGELLG-RDRVGADDSFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFE
MSMEG_4511|M.smegmatis_MC2_155      LFAELLE-RDEVGADDSFFDLGGHSLLATKLVAAVRARCAVDVGVQDVFE
Mflv_2696|M.gilvum_PYR-GCK          LFSELLG-VARVGVDDSFFELGGHSLLATKLVSAVRSRCGVDMEIREIFE
MAV_2013|M.avium_104                LFSGLLG-HERVGVDDSFFDLGGHSLVATKLVTAIRAECGVEIGIRDVFE
MMAR_3691|M.marinum_M               IFAQLFG-RQRVGAEDSFFGLGGHSLLAARLVAQIRAEFGVDLTVRTIFD
MUL_3634|M.ulcerans_Agy99           IFAQLFG-RQRVGAEDSFFGLGGHSLLAARLVAQIRAEFGVDLTVRTIFD
MAB_2122|M.abscessus_ATCC_1997      IYSHLFG-KERVGLDDSFFELGGHSLLAARLVAQIRAQFGIDLTVRAVFD
MLBr_01996|M.leprae_Br4923          IWSRHLG--RAILPDSSLLDEGIGSVDLIRILPDTRRHLGRHLSLLDLIS
                                    ::.  :     :  :.*::  *  *:   :::.  *   . .: :  ::.

Mvan_3845|M.vanbaalenii_PYR-1       NATIARLAA------------HLDTMGRATI-------GTRRPRLVAAPL
TH_3141|M.thermoresistible__bu      LGTVARLAG------------RIDELRSGSG-------GPLRPRLTPQHF
Mb2401c|M.bovis_AF2122/97           FATVTALAG------------HIDTLDSDS----------ARPRLTRVDH
Rv2380c|M.tuberculosis_H37Rv        FATVTALAG------------HIDTLDSDS----------ARPRLTRVDH
MSMEG_4511|M.smegmatis_MC2_155      HATVSGLAA------------HIEDLVASGA-------SSGRPAIVAVPH
Mflv_2696|M.gilvum_PYR-GCK          LGTVARLAE------------RVDELAAGGS-------APLRPRLLAVPH
MAV_2013|M.avium_104                LATVGLLAE------------RVDQLSSGEL-------TGTRPKLIATAH
MMAR_3691|M.marinum_M               APTPAGLAARLVERFRNDFELDLDNLAADD---MPLDPKRARPGFVKSAR
MUL_3634|M.ulcerans_Agy99           VPTPAGLAARLVERFRNDFELDLDNLAADD---MPLDPKQARPGFVKSAR
MAB_2122|M.abscessus_ATCC_1997      RPTPAGLAEQLVTYFREEFEIELDELDLDESDEMEAAPQDGRPDLVAAER
MLBr_01996|M.leprae_Br4923          ADNAANLTAA-----------QTANVWMDVG---------TAAEIERDLA
                                      .   *:                 :                . :     

Mvan_3845|M.vanbaalenii_PYR-1       DGPAPLSSSQLRSWFGYRIEGRSPVNNIPFAARLTGPCDVDAFVAAIRDV
TH_3141|M.thermoresistible__bu      DGPAPLSSSQLRSWFAYRVDGPSVVNNIPFAARLHGPVDVDALEAAIGDV
Mb2401c|M.bovis_AF2122/97           DGPVRLSSSQMRSWFNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDV
Rv2380c|M.tuberculosis_H37Rv        DGPVRLSSSQMRSWFNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDV
MSMEG_4511|M.smegmatis_MC2_155      DGPLQMSAAQLRQWFQFRIDGPNPVNNVPFAARLSGPCDVDALIAAVGDV
Mflv_2696|M.gilvum_PYR-GCK          DGPAPMSAAQLRQWFQYRIEGPGPVNNVPFAARFAGPCDVDALIEAVRDV
MAV_2013|M.avium_104                DEPLPLSASQLRSWFAYRMDGPSPVNNIPFAARLTGPWDIDALIAAVGDV
MMAR_3691|M.marinum_M               PQRLPLSHSQLAAWFQYRIEGAREEFNMPLALRFEGPLDSVALAAALNDV
MUL_3634|M.ulcerans_Agy99           PQWLPLSHSQLAAWFQYRIEGAREEFNMPLALRFEGPLDSVALAAALNDV
MAB_2122|M.abscessus_ATCC_1997      PERLPLSSSQLSMWFECQMEGVTDIGNMWLALRFDGPLQTPALIAALNDV
MLBr_01996|M.leprae_Br4923          SLCRQRNATEFSVKQTRNSHQKQAIVVLGASGILGTGFAQAVLDLRQSGV
                                          . :::      . .       :  :  :       .:     .*

Mvan_3845|M.vanbaalenii_PYR-1       VERHAILRTTYREIDGVPYQIVNPISD-VPVRRARGEGEQWLQAELDRER
TH_3141|M.thermoresistible__bu      IARHEILRTVYREIDGVPYQIVLPTEP-VPVRRADGQGEQWLRAELDAER
Mb2401c|M.bovis_AF2122/97           VARHEILRTVYREIGGVPHQIIQPPAE-VPVRCAAGSDAAWLRAELNNER
Rv2380c|M.tuberculosis_H37Rv        VARHEILRTVYREIGGVPHQIIQPPAE-VPVRCAAGSDAAWLRAELNNER
MSMEG_4511|M.smegmatis_MC2_155      VARHEILRTTYREIDGAPYQIIHPPAP-VPVRQARGDGEDWVQAQLDAER
Mflv_2696|M.gilvum_PYR-GCK          VNRHESLRTTFCEIDGVPYQLVNAPDPGFPVRRDSGPDDAWLVGALDDER
MAV_2013|M.avium_104                VARHEILRTRYVELDGVPYQVVGPPGVEIPVRREDGPDDPWLQQQLDAER
MMAR_3691|M.marinum_M               VARHEALRTNFDEHEGVPYQIVHPSRTVQLAVRAIDQDE--FDDVSTQLR
MUL_3634|M.ulcerans_Agy99           VARHEALRTNFDEHEGVPYQIVHPSRTVQLAVRAIDQDE--FDDVSTQLR
MAB_2122|M.abscessus_ATCC_1997      VARHEALRTNIAIHEGAPYQIVHPSRELAVPILRSSPEG--LSDTLAELR
MLBr_01996|M.leprae_Br4923          LCPEVVLATRARLPEGDPWTALQGVDG-----------------------
                                    :  .  * *      * *   :                            

Mvan_3845|M.vanbaalenii_PYR-1       KHTFDLEEDWPIRAAVFTVGAVSPASDGGAVSPASDGGAVDPASDHVLSV
TH_3141|M.thermoresistible__bu      RHVFDLENERPIRPAILSLRPDAGSPD----SPAGD--------VHVLSL
Mb2401c|M.bovis_AF2122/97           GYVFDLETDWPIRAALLSTPEQT-----------------------VLSL
Rv2380c|M.tuberculosis_H37Rv        GYVFDLETDWPIRAALLSTPEQT-----------------------VLSL
MSMEG_4511|M.smegmatis_MC2_155      RYCFDLETDWPIRAAVLTTAEHH-----------------------VLSL
Mflv_2696|M.gilvum_PYR-GCK          RRVFDLENQWPIRVAVLSIPGEH-----------------------ALSV
MAV_2013|M.avium_104                RHCFELDGELPIRVAVLRVANAAEH---------------------VLSL
MMAR_3691|M.marinum_M               RHVFTPESGPLLQANLLVLGPDTH----------------------VLLL
MUL_3634|M.ulcerans_Agy99           RHVFTPESGPLLQANLLVLGPDTH----------------------VLLL
MAB_2122|M.abscessus_ATCC_1997      HHIFGLETESLIRPAIIELSAQEH----------------------VLAL
MLBr_01996|M.leprae_Br4923          -----------VRIERISFENGPG----------------------ELEA
                                               ::   :                              *  

Mvan_3845|M.vanbaalenii_PYR-1       VIHHIAGDHWSGGVLFTDLVAAYRARKAGERPTWAPLPVQYTDYGAWQAE
TH_3141|M.thermoresistible__bu      VMHHIAGDHWSATVLFTDLLTAYRARTAGQEPAWAPLPVQYADFGAWESE
Mb2401c|M.bovis_AF2122/97           VVHHIAGDHWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSA
Rv2380c|M.tuberculosis_H37Rv        VVHHIAGDHWSAGVLFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSA
MSMEG_4511|M.smegmatis_MC2_155      VVHHIAADHWSGTVLFTDLLTAYHARHAGSAVELPPLPVQYADFAAWQAE
Mflv_2696|M.gilvum_PYR-GCK          VVHHIAADHWSGGVLFTELLTAYRARRAGEAPTWAPLPVQYADYAAWQSA
MAV_2013|M.avium_104                VVHHIASDHWSAGVLFADVMTAYRARRGGEAPSWAPLRVQYADYAAWQRT
MMAR_3691|M.marinum_M               IVHHIVSDHASLEIVFDDLIVAYRARLQHNAPQWDILPIQFADYAVWQRN
MUL_3634|M.ulcerans_Agy99           IVHHIVSDHASLEIVFDDLIVAYRARLQHNAPQWDILPIQFADYAVWQRN
MAB_2122|M.abscessus_ATCC_1997      VVHHIVVDHASFTVIVDDLIAAYRARLEGQAPQWDPQPVQYADYVLWQRD
MLBr_01996|M.leprae_Br4923          LIRDTDAGTLVNGVGNTNMLVPYRELRLANVELVSAIVDICASYSTRLVH
                                    :::.   .     :   :::..*:     .           :.:      

Mvan_3845|M.vanbaalenii_PYR-1       LLSDDTG----IAGPQREYWIRQLADAPVESGLPLEFSRPRLPSGKGDAV
TH_3141|M.thermoresistible__bu      LLAEETG----IAGPQREYWTRQLAGLPEETGLRPDFPRPPVPSGLAEAV
Mb2401c|M.bovis_AF2122/97           LLDDGAG----IVGPQRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAV
Rv2380c|M.tuberculosis_H37Rv        LLDDGAG----IVGPQRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAV
MSMEG_4511|M.smegmatis_MC2_155      LLAGTDD----TIDEQRRYWTTQLAGLPEENGLYPDFPRPPVPTGDGAAL
Mflv_2696|M.gilvum_PYR-GCK          LLADDSG----IVAAQRRYWTQQLEGLSAETGLQPDLVRPSVPSGAADAV
MAV_2013|M.avium_104                FLGDAGGQESAVAGAQREYWTRQLAGLPEDTGLRPDFPRQPVPSGDGESV
MMAR_3691|M.marinum_M               TFESN------WGQTELDYWRDALAGLPDEISVATDRARPRVLGKRGEVV
MUL_3634|M.ulcerans_Agy99           TFESN------WGQTELDYWRDALAGLPDEISVATDRARPRVLGKRGEVV
MAB_2122|M.abscessus_ATCC_1997      AFAPDSE----FGQAEVNFWRQQLAGVPTEIAVAHDRARPQILGKRGEVA
MLBr_01996|M.leprae_Br4923          LSSFVVN---------------ADVTVPQVTDPRETPYPYAASKSLAELV
                                                               .                  .   

Mvan_3845|M.vanbaalenii_PYR-1       EFTIDGQVRRQITELCRELGITEFMLLQAAVAVTLAKVGGGLDIPLGTPV
TH_3141|M.thermoresistible__bu      EFTIDAAVREKLAGLCRDLGITEFMALQAAVAVVLHKAGSGSDIPLGTPV
Mb2401c|M.bovis_AF2122/97           EFRLGAAIRDKLAAVSRDLGVTEFMLLQAAVAVVLHKAGGGVDVPIGAPV
Rv2380c|M.tuberculosis_H37Rv        EFRLGAAIRDKLAAVSRDLGVTEFMLLQAAVAVVLHKAGGGVDVPIGAPV
MSMEG_4511|M.smegmatis_MC2_155      DFSIDADTRARLIALTRELGVTEFMLLQAAVAIALHKSGQGTDIPLGTPV
Mflv_2696|M.gilvum_PYR-GCK          EFTLDAAIREKLVTLSREVGATEFMLLQAAVAVTLYKAGEGPDIPLGTPV
MAV_2013|M.avium_104                DFHIDAATRAKLADVCRELGITEFMLLQTAVAVVLHKAGGGVDIPLGTPV
MMAR_3691|M.marinum_M               QFSVPAARRAALTQLAERNGATEFMLYQAALAVVLHKLGGGTDIALGSPV
MUL_3634|M.ulcerans_Agy99           QFSVPAARRSALTQLAERNGATEFMLYQAALAVVLHKLGGGTDIALGSPV
MAB_2122|M.abscessus_ATCC_1997      KFVMEPERRQALTRMAEQRGVTEFMVYQAALAVVLHRLGGGTDIVIGSPV
MLBr_01996|M.leprae_Br4923          VAGSPSALDFTIVRLPRVLGEDYQLRNSSDILLSIVDACIALRAYPSATV
                                               :  : .  *    :  .: : : :     .     .:.*

Mvan_3845|M.vanbaalenii_PYR-1       AGRSEA--ELEQLVGFFVNFVVLRNDLRGNPTLREVLIRAREMALSAYSN
TH_3141|M.thermoresistible__bu      AGRSEP--ELDQLVGFFINILVLRNDLSGNPSLREVCRRAREMALAAYAH
Mb2401c|M.bovis_AF2122/97           AGRSEA--NLDQLIGFFINIVVLRNDLRGNPTLREVLQRTRQMALAAYAH
Rv2380c|M.tuberculosis_H37Rv        AGRSEA--NLDQLIGFFINIVVLRNDLRGNPTLREVLQRTRQMALAAYAH
MSMEG_4511|M.smegmatis_MC2_155      AGRTAP--ELDALIGFFINIVVLRNDLSGNPSLREVLRRSREMALAAYQH
Mflv_2696|M.gilvum_PYR-GCK          AGRTES--ELDQLIGFFINILVLRNDLRDNPSLRDVGFRSREMALAAYAH
MAV_2013|M.avium_104                AGRTEA--ELDQLIGFFVNILVLRNDLDGNPTLRELLKRARETALAAYAH
MMAR_3691|M.marinum_M               AARVEP--ATAQLVGLFANVVVLRTDLSGDPTLRSILVGSRDTVLDALAH
MUL_3634|M.ulcerans_Agy99           AARVEP--ATAQLVGLFANVVVLRTDLSGDPTLRSILVGSRDTVLDALAH
MAB_2122|M.abscessus_ATCC_1997      AARVHP--HVAKLVGLFANMVALRNDLSGDPSLRSVLERSRDATLNAHAH
MLBr_01996|M.leprae_Br4923          TEEVTTGRAAAKAILGVVSALARSGQLGSGISVVRGEAVAYADFLSEFAS
                                    : .  .       :  . . :.   :* .. ::      :    *     

Mvan_3845|M.vanbaalenii_PYR-1       QDVPFEQVVEAVNPPRTLARNPLFQVVVHVREQLPQRQMIDT--------
TH_3141|M.thermoresistible__bu      QDLPFDQVVDAVSPVRTLARNPLFSVVVHVREQLPENRVIDHGPDG----
Mb2401c|M.bovis_AF2122/97           QDLPFDQVVEAVNPQRSLSRNPLFDIVVHVREQMPQDHVIDTGPDG----
Rv2380c|M.tuberculosis_H37Rv        QDLPFDQVVEAVNPQRSLSRNPLFDIVVHVREQMPQDHVIDTGPDG----
MSMEG_4511|M.smegmatis_MC2_155      QDLPFDRVVDAVSPVRSLSRNPLFGVVVHVRDDLPADQVIDDGGNG----
Mflv_2696|M.gilvum_PYR-GCK          QDLPFDQVVDAVSPVRSLSRNPLFGVVVHVREELPQDRVIATGSDG----
MAV_2013|M.avium_104                QDLPFDRVVDSVSPVRSLSRNPLFQVVVHVRDHLSATRVIETAPVGGDGQ
MMAR_3691|M.marinum_M               QELPIERLVEALNPPRALSRNPLFQNMLNFRGEDWALVPRDLTGRG----
MUL_3634|M.ulcerans_Agy99           QELPIERLVEALNPPRALSRNPLFQNMLNFRGEDWALVPRDLTGRG----
MAB_2122|M.abscessus_ATCC_1997      QELPIEKLVEAVNPVRSLSWNPLFQTMVNFRGADWGTAARDVTVSG----
MLBr_01996|M.leprae_Br4923          DELNMAEWKYRLDQSDWAKRNPRRWSVIDAWFTLG---------------
                                    ::: : .    :.       **    ::.                     

Mvan_3845|M.vanbaalenii_PYR-1       DTEFTALEPTFDIAQADLSLNFLA---------DGTGYRGYLIYRPELYA
TH_3141|M.thermoresistible__bu      DTTVTVLEPPFDAAHADLSLNFFAAE-------DGGGYRGHVIYRPELYS
Mb2401c|M.bovis_AF2122/97           DTTLRVLEPTFDAAQADLSVNFFA---------CGDEYRGHVIYRTELYE
Rv2380c|M.tuberculosis_H37Rv        DTTLRVLEPTFDAAQADLSVNFFA---------CGDEYRGHVIYRTELYE
MSMEG_4511|M.smegmatis_MC2_155      ETRFTALEPTFDVAHADLSLNFFAQNGNGGRAGEPAGYKGTVIYRTELYE
Mflv_2696|M.gilvum_PYR-GCK          ETTFTALEPTFDMAHADLSVNFFAG---------GNGYRGHVIYRTELYT
MAV_2013|M.avium_104                DTVCTSLDPVFDMAHADLSVNFFGTDG-----AGDIGYNCHLIFRTDLYR
MMAR_3691|M.marinum_M               ETTVVPLPVNFEVALLFLAIGMSVTP--------SGELDVQVIANADLYE
MUL_3634|M.ulcerans_Agy99           ETTVVPLPVNFEVALLFLAIGMSVTP--------SGELDVQVIANADLYE
MAB_2122|M.abscessus_ATCC_1997      ETTVVPLPMEVDVSYLDLNFALNVTP--------SGGLDVSVVANADLYD
MLBr_01996|M.leprae_Br4923          ---------------------------------MMFEMRSYAEYPTMALG
                                                                                 .    

Mvan_3845|M.vanbaalenii_PYR-1       RRTIERLGRWLPRVVAAFVDTPDRALGDVDIVSAEERQRVSQEWST----
TH_3141|M.thermoresistible__bu      RDTAQRFADWLGRVVTAFAERPDITLRELEIGAPGERRRILEEWG-----
Mb2401c|M.bovis_AF2122/97           RATAQRFADWLVRVVEAFADRPDQPLREVEMVSAQARRRILDRSNAGAG-
Rv2380c|M.tuberculosis_H37Rv        RATAQRFADWLVRVVEAFADRPDQPLREVEMVSAQARRRILDRSNAGAG-
MSMEG_4511|M.smegmatis_MC2_155      PATARRLIGWLHRIIDAFATDADTTLRDIAVIDADERTLLIEDWSRRAVP
Mflv_2696|M.gilvum_PYR-GCK          RATAERFAGWLSAVITAFADDPERHVDDVVIAEPVRPG------------
MAV_2013|M.avium_104                RTTIERLAGWLVRAVTAFADDLDQTLRDVALIDAGEQQRILRQWSRGAQP
MMAR_3691|M.marinum_M               PATVALIADALDAALAAFATTPDLPLSAVQLLPS----------------
MUL_3634|M.ulcerans_Agy99           PATVALIADALDAALAAFATTPDLPLSAVQLLPR----------------
MAB_2122|M.abscessus_ATCC_1997      HETTRMIAQALDTAFDAFVNNQESRVSEIVLLPA----------------
MLBr_01996|M.leprae_Br4923          VESVAELAAPPESIRALLAHGCSQPLKYTGR-------------------
                                      :   :          :.   .  :                        

Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      PA------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2013|M.avium_104                PRDRPRTIPELLQASRSLGADRIAVRCGAEHIDYPALHRRSDNLAALLVD
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2013|M.avium_104                RGVGPGTLVGLSTRRSIELVVALVAIMKAGAGYFPVDPGYPSARKQFMLD
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2013|M.avium_104                DVRPPVVVATVEAVDTMPGLPGVELLSLDDPQVRALVDRDDVDPRAGRLR
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2013|M.avium_104                PPHPDDPMYLVFTSGSTGKPKGAVGTHRSMAARLDWQLRHYPPRTDDVRL
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2013|M.avium_104                AQASITFLEGGMEMLAGLAAGATMILADDAEHRDPEALGELMHRHSVAQV
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2013|M.avium_104                TAVPSLVSALLDSRPDAVRSLSRLVCGGEPVSTSLLQRLVSVCDEADGGG
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       ---------------------------------GARVQVLDADLAPAPVG
TH_3141|M.thermoresistible__bu      ---------------------------------GGTVYVLDETLQPVPVG
Mb2401c|M.bovis_AF2122/97           ---------------------------------TARVYLLDDALKPVPVG
Rv2380c|M.tuberculosis_H37Rv        ---------------------------------TARVYLLDDALKPVPVG
MSMEG_4511|M.smegmatis_MC2_155      ---------------------------LPQTEGATNVYVLDEWLEPVAIG
Mflv_2696|M.gilvum_PYR-GCK          --------------------------------DGAEAVLLDGAGHPVPVG
MAV_2013|M.avium_104                PELLNNIGSTETSGAVSRGPLSPPNPLVGKPVPGAQAYLLDDGLRPVPVG
MMAR_3691|M.marinum_M               ---------------------------------ADLAKLLAPPLPAGPAA
MUL_3634|M.ulcerans_Agy99           ---------------------------------ADLAKLLAPPLPAGPAA
MAB_2122|M.abscessus_ATCC_1997      ---------------------------------DAMAQLMAPPAAAVEPV
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       VFGDLYLSG--------------------------------------GPF
TH_3141|M.thermoresistible__bu      VVGDVYTAGPALAAAHWTRAGVTA-------------TRLVADPVGNRPG
Mb2401c|M.bovis_AF2122/97           VVGDVYYGGGPAVGARLARPSETA-------------TRFVADPFAAQPG
Rv2380c|M.tuberculosis_H37Rv        VVGDVYYGGGPAVGARLARPSETA-------------TRFVADPFAAQPG
MSMEG_4511|M.smegmatis_MC2_155      VIGDVYYAGGAVDASAEAANGVAA-------------QRFVPNPFG---A
Mflv_2696|M.gilvum_PYR-GCK          VVADVHYAGAPDRRGDRARWTEDGRLQYVERVDHDLEAALAAVPGVAAAA
MAV_2013|M.avium_104                VVGELYYAGDQLARGYWKRPGLTA-------------ARFVANPFGAEPG
MMAR_3691|M.marinum_M               SP------------------------------------------------
MUL_3634|M.ulcerans_Agy99           SQ------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      TT------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       AQRHRTGDRARWD--------DDGRLEIAARAPGATVVEVAPPA------
TH_3141|M.thermoresistible__bu      ARLYRTGDRARWI--------ADGVLEFVDAQP-PTIPAVRPDS------
Mb2401c|M.bovis_AF2122/97           SRLYRNGERGVWK--------ADGQLELLAEIERLPTAQAAP--------
Rv2380c|M.tuberculosis_H37Rv        SRLYRNGERGVWK--------ADGQLELLAEIERLPTAQAAP--------
MSMEG_4511|M.smegmatis_MC2_155      GRLYRTGDRARWT--------PDGRLEPVTAGEPRLQAALEAVDGVAAAA
Mflv_2696|M.gilvum_PYR-GCK          VRTWEIGHRTAVVGYVVPAEPVDDPASFAETVRAAVAPESAPTSITVLDA
MAV_2013|M.avium_104                SRLYRSGDLARWT--------EDGQLEFVGRSDHQVQVRGFRVELAEVEA
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3141|M.thermoresistible__bu      --------------------------------------------------
Mb2401c|M.bovis_AF2122/97           --------------------------------------------------
Rv2380c|M.tuberculosis_H37Rv        --------------------------------------------------
MSMEG_4511|M.smegmatis_MC2_155      TRYWEN-------------------------RSAPLLAAYVVADAAHAAD
Mflv_2696|M.gilvum_PYR-GCK          LP------------------------------------------------
MAV_2013|M.avium_104                ALAGADGVAAAAARTWEVHGGTSLAGYVVPQRPIADEAEKAAFAAQVRAE
MMAR_3691|M.marinum_M               --------------------------------------------------
MUL_3634|M.ulcerans_Agy99           --------------------------------------------------
MAB_2122|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       ---------------------------------------VEFE--EPRTD
TH_3141|M.thermoresistible__bu      ---------------------------------------GQRPGGPPATD
Mb2401c|M.bovis_AF2122/97           -----------------------------------------VPAEPADTE
Rv2380c|M.tuberculosis_H37Rv        -----------------------------------------VPAEPADTE
MSMEG_4511|M.smegmatis_MC2_155      PQFAEQVRTALPDEFAGAAITVVDDLTPAALTRPRVSATASGPFEAPATP
Mflv_2696|M.gilvum_PYR-GCK          -----------------------------ATRRALPAPRVGGPSEPARTD
MAV_2013|M.avium_104                IAATLPGYMMPSSLTVLDALPKTESGKLNRPGLPRPAVSTGGRTEPARTD
MMAR_3691|M.marinum_M               ------------------------------------------PVAAGSAE
MUL_3634|M.ulcerans_Agy99           ------------------------------------------PVAAGSAE
MAB_2122|M.abscessus_ATCC_1997      ------------------------------------------PSVEGSEE
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       SERALAALLSELLATEEVG----RHDDFFGLGGDSVLAVQLAARARDTGL
TH_3141|M.thermoresistible__bu      TERALATLLAEVLDTEVTG----RDDDFFSLGGDSILAVQLAARARDTGL
Mb2401c|M.bovis_AF2122/97           TERALAAILADVLEVGEVG----RYDDFFNLGGDSILATQVAARARDGGI
Rv2380c|M.tuberculosis_H37Rv        TERALAAILADVLEVGEVG----RYDDFFNLGGDSILATQVAARARDGGI
MSMEG_4511|M.smegmatis_MC2_155      TERAVAAMLVELLGVTQVG----RHDDFFTLGGDSILAVQLAARARDAGV
Mflv_2696|M.gilvum_PYR-GCK          TEKALVGMLADVLVEVHDGTGIGRFDDFFELGGDSILAVQLAARAKQAGL
MAV_2013|M.avium_104                TERALANVFAELLSTPEVG----RFDDFFALGGDSILSVQLASRARAAGL
MMAR_3691|M.marinum_M               TERRLTAMLEELLEITGID----RDENYFALGGDSIIAIKWSAQAGALGL
MUL_3634|M.ulcerans_Agy99           TERRLTAMLEELLEITGID----RDENYFALGGDSIIAIKWSAQAGALGL
MAB_2122|M.abscessus_ATCC_1997      TKLVLISILEELLEISDVD----PEDNFFALGGDSVISIQWSTRAAERGL
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       DLTARMVFEHPRLAELAAALDS----------------------GAGAAA
TH_3141|M.thermoresistible__bu      KLTARMVFEHPTLHELAAAVEAREAVEARETAEAGGAEAGGAESGGGADG
Mb2401c|M.bovis_AF2122/97           PLTARMVFEHPVLCELAAAVDA----------------------KPHVEA
Rv2380c|M.tuberculosis_H37Rv        PLTARMVFEHPVLCELAAAVDA----------------------KPHVEA
MSMEG_4511|M.smegmatis_MC2_155      AMTARMVFEHPVLSELAAAIDA-----------------------AGEGS
Mflv_2696|M.gilvum_PYR-GCK          RLSARMVFEHPVVHDLAVALDT------------------------AKTP
MAV_2013|M.avium_104                PVSPRMIFENPTVQQLAAALDALGD-----------------NDSDGRLD
MMAR_3691|M.marinum_M               PFPPAMVFEHMTIAELAAAVDA---------------------ANGEPVV
MUL_3634|M.ulcerans_Agy99           PFPPAMVFEHMTIAELAAAVDA---------------------ANGEPVV
MAB_2122|M.abscessus_ATCC_1997      AMTPQMVFECATIAQLAGAVDA---------------------ADR-VVT
MLBr_01996|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mvan_3845|M.vanbaalenii_PYR-1       EQP----------DTHHAPMSVSGLSEDELAALTASWG-TGE---
TH_3141|M.thermoresistible__bu      AERGAAAGDSGNGAASHAPMSTSGLSAEQLSALTASWNPAGEDAP
Mb2401c|M.bovis_AF2122/97           EPD----------DKHHAPMSTSGLSPDELSALTASWDQWP----
Rv2380c|M.tuberculosis_H37Rv        EPD----------DKHHAPMSTSGLSPDELSALTASWDQWP----
MSMEG_4511|M.smegmatis_MC2_155      AAQ----------DVHHAPMEASGLSSDELAALTAAWGQSQDGKR
Mflv_2696|M.gilvum_PYR-GCK          EVA----------DVRHDPMSASGLTPEELAMVATSWAAEQDGSP
MAV_2013|M.avium_104                DQP---------ADTRFEPMSTSGLSASDLAAVTQLWSSSREGTA
MMAR_3691|M.marinum_M               EAD-------PPPAQEYTPMSASGLAPDALAKLSASWLQQGSAS-
MUL_3634|M.ulcerans_Agy99           EAD-------PPPAQEYTPMSASGLAPDALAKLSASWLQQGSAS-
MAB_2122|M.abscessus_ATCC_1997      EGDS----HLVTPPVQSAPMSASGLSADALAELTASWQAQS----
MLBr_01996|M.leprae_Br4923          ---------------------------------------------