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VTETTGAGTRLDDERLELLRRKLAERGLSRSAGTARHDEPRMSVGQHRMWFVQSVDPDSALLNICVSYRL TGGVDTGRLHRAVDAVAARHPVLHTTYDTTDEGDPRPVLRADLRPEWAEHDLSGLTEQARRLRLDVLAQR DFRRPFDLSKDSPLRVTAARLADDELMLLITAHHIAWDDGSWAPFFADLTRAYTAPGDFDATPVVPDLSA DPTAIRREDLDYWRPLMADLPEPLELPGPNGSVVPSTWRAQRAFAELPAEIVDRAAALARETGATPYMVL MAAFAALVHRYTGSTDFLVAAPVLNRGAATENVIGYYGNTVVIRLRPQSHQSFRELLAQTRDGAVGAFAH SRADLDWLVRESNPDRRHGADRMTRVSFGQREPDGAGFCPPGVRCERGDLRGHFNQLPLSLMVELNRTPD GSGGGLVEAEYLVEVLDQQLVEQMLRHYRTLLDSLLSDPDATLSACALMSDADAEWLRAVSTGEQFITPA ATLSELVSRRAARTPDAVAVVYEGRTYTYRDIEEESNRVAHWLIERGVGTEDRVAVLLDKSPELVITALG VLKAGGVYLPVDPTYPQDRLNFILGDADAKLVLREPVTDLADYPATAPTELLRPLTPQNTAYLIYTSGST GLPKGVPVPHAPIAEYFVWFGDEYRIDETDRLLQVASPSFDVSIGEIFGTLIMGARLVIPRPDGLRDIGY LTELLAREGITSMHFVPSLLGLFLSLPGVSQWRTLRRVPIGGEALPGEIADKFHATFDASLYNFYGPTET VVNCTSYPVEGAQGTRVVPIGRPKINTRVYLLDNALQPVPPGVIGEIYIAGTHVAHGYHRRPQLTAERFV ADPFSRGGRMYRSGDLARRNANGDIEFVGRADEQVKIRGFRIELGEIAAAISVDPSVGQAVVLAMDLPQL GKSLVGYVTPAQGAGTETVDVERIRARVAAALPDYMTPAAYVVLDEIPITAHQKIDRAALPQPQIGAGTE YRDPTTPTEHRIAQLFSGLLGHERVGVDDSFFDLGGHSLVATKLVTAIRAECGVEIGIRDVFELATVGLL AERVDQLSSGELTGTRPKLIATAHDEPLPLSASQLRSWFAYRMDGPSPVNNIPFAARLTGPWDIDALIAA VGDVVARHEILRTRYVELDGVPYQVVGPPGVEIPVRREDGPDDPWLQQQLDAERRHCFELDGELPIRVAV LRVANAAEHVLSLVVHHIASDHWSAGVLFADVMTAYRARRGGEAPSWAPLRVQYADYAAWQRTFLGDAGG QESAVAGAQREYWTRQLAGLPEDTGLRPDFPRQPVPSGDGESVDFHIDAATRAKLADVCRELGITEFMLL QTAVAVVLHKAGGGVDIPLGTPVAGRTEAELDQLIGFFVNILVLRNDLDGNPTLRELLKRARETALAAYA HQDLPFDRVVDSVSPVRSLSRNPLFQVVVHVRDHLSATRVIETAPVGGDGQDTVCTSLDPVFDMAHADLS VNFFGTDGAGDIGYNCHLIFRTDLYRRTTIERLAGWLVRAVTAFADDLDQTLRDVALIDAGEQQRILRQW SRGAQPPRDRPRTIPELLQASRSLGADRIAVRCGAEHIDYPALHRRSDNLAALLVDRGVGPGTLVGLSTR RSIELVVALVAIMKAGAGYFPVDPGYPSARKQFMLDDVRPPVVVATVEAVDTMPGLPGVELLSLDDPQVR ALVDRDDVDPRAGRLRPPHPDDPMYLVFTSGSTGKPKGAVGTHRSMAARLDWQLRHYPPRTDDVRLAQAS ITFLEGGMEMLAGLAAGATMILADDAEHRDPEALGELMHRHSVAQVTAVPSLVSALLDSRPDAVRSLSRL VCGGEPVSTSLLQRLVSVCDEADGGGPELLNNIGSTETSGAVSRGPLSPPNPLVGKPVPGAQAYLLDDGL RPVPVGVVGELYYAGDQLARGYWKRPGLTAARFVANPFGAEPGSRLYRSGDLARWTEDGQLEFVGRSDHQ VQVRGFRVELAEVEAALAGADGVAAAAARTWEVHGGTSLAGYVVPQRPIADEAEKAAFAAQVRAEIAATL PGYMMPSSLTVLDALPKTESGKLNRPGLPRPAVSTGGRTEPARTDTERALANVFAELLSTPEVGRFDDFF ALGGDSILSVQLASRARAAGLPVSPRMIFENPTVQQLAAALDALGDNDSDGRLDDQPADTRFEPMSTSGL SASDLAAVTQLWSSSREGTA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_2013 | - | - | 100% (2190) | linear gramicidin synthetase subunit D |
M. avium 104 | MAV_3056 | - | 0.0 | 37.38% (2202) | linear gramicidin synthetase subunit D |
M. avium 104 | MAV_3239 | - | 0.0 | 36.77% (2238) | syringomycin synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2401c | mbtE | 0.0 | 65.41% (1506) | peptide synthetase MBTE (peptide synthase) |
M. gilvum PYR-GCK | Mflv_2696 | - | 0.0 | 65.34% (1529) | amino acid adenylation domain-containing protein |
M. tuberculosis H37Rv | Rv2380c | mbtE | 0.0 | 65.41% (1506) | peptide synthetase MBTE (peptide synthase) |
M. leprae Br4923 | MLBr_00134 | fadD22 | 7e-25 | 26.03% (484) | acyl-CoA synthetase |
M. abscessus ATCC 19977 | MAB_2122 | - | 0.0 | 43.48% (1571) | putative peptide synthetase MbtE |
M. marinum M | MMAR_3691 | mbtE | 0.0 | 43.61% (1566) | non-ribosomal peptide synthetase MbtE |
M. smegmatis MC2 155 | MSMEG_4511 | - | 0.0 | 65.17% (1559) | linear gramicidin synthetase subunit B |
M. thermoresistible (build 8) | TH_3141 | - | 0.0 | 66.30% (1558) | PUTATIVE amino acid adenylation domain |
M. ulcerans Agy99 | MUL_3634 | mbtE | 0.0 | 43.47% (1569) | non-ribosomal peptide synthetase MbtE |
M. vanbaalenii PYR-1 | Mvan_3845 | - | 0.0 | 62.46% (1569) | amino acid adenylation domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb2401c|M.bovis_AF2122/97 -------------------------------------------------- Rv2380c|M.tuberculosis_H37Rv -------------------------------------------------- TH_3141|M.thermoresistible__bu VTDTTETRPAGADDEARLALLRRRLSERGLSA--QQTTG---AASEDR-- Mvan_3845|M.vanbaalenii_PYR-1 ---MTDIDTGALLDERRLELLRRRMQERGLSAGTDTAEP---AGDTDV-- MSMEG_4511|M.smegmatis_MC2_155 MTDIADTATAS-TVEARLELMRRKLAERGLAAGRAAAEGSAAAVDPTV-- Mflv_2696|M.gilvum_PYR-GCK -------MTDTDLDARRLELLRRRLAGSGLRE-QDPAEPVAVAADPARGE MAV_2013|M.avium_104 --MTETTGAGTRLDDERLELLRRKLAERGLSRSAGTARH-----DEPR-- MMAR_3691|M.marinum_M -----MADDVRTLQDRRRELLRRRIAESGLAAEQSSDQPGICPGERYR-- MUL_3634|M.ulcerans_Agy99 -----MADDVRTLQDRRRELLRRRIAESGLAAEQSSDQPRICPGERYR-- MAB_2122|M.abscessus_ATCC_1997 -----MTGDQLSALDRRRELLRRRLAESGVAAQAVESAPRVQAGERRG-- MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 -------MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHR Rv2380c|M.tuberculosis_H37Rv -------MWFVQMADPSGALLNICVSYRITGDIDLARLRDAVNAVARRHR TH_3141|M.thermoresistible__bu LSDGQLRMWFVHQADPSGALLNICLSYRISGPVDLAALRGALDAVARRHP Mvan_3845|M.vanbaalenii_PYR-1 LTEGQLRMWFVHNADPSGALLNVCLSYRLSGEIDVARLHDAVGAVARRHR MSMEG_4511|M.smegmatis_MC2_155 LSDGQRRMWFVQGFDPSGVLLNVSLSYRLTGDIDAERMQAAVEAVARRHP Mflv_2696|M.gilvum_PYR-GCK FTDGQKRMWFVHSVDPSGVLLNVCLSYRISGEVDLARLHDAVTAVARRHP MAV_2013|M.avium_104 MSVGQHRMWFVQSVDPDSALLNICVSYRLTGGVDTGRLHRAVDAVAARHP MMAR_3691|M.marinum_M LSDGQRRMWFLQTMDPDDVTLNICVAYRLAGLVDEDRLHTAVNDVVARHA MUL_3634|M.ulcerans_Agy99 LSDGQRRMWFLQTMDPDDVTLNICVAYRLTGLVDEDRLHTAVNDVVARHA MAB_2122|M.abscessus_ATCC_1997 LAPGQRRMWFMQTKDPADTSLNICVAHRMRGALDQTRLRDAVAAVIRRHD MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 ILRTTY-----PVGDDGVAQPTVHADLRPGWTQYDLTDLS---QRAQRLR Rv2380c|M.tuberculosis_H37Rv ILRTTY-----PVGDDGVAQPTVHADLRPGWTQYDLTDLS---QRAQRLR TH_3141|M.thermoresistible__bu VLRTTY-----AADENGEPRPTVHAELRPGWTEHDLTDLADQSEQARRLR Mvan_3845|M.vanbaalenii_PYR-1 VLRTTYRTESTAAGDSGMPVPTVHTGLMPGWAEHDLSELS---ERARGLR MSMEG_4511|M.smegmatis_MC2_155 ILRTTF-----HADENGEPRAEVHDDLTPSWTTHDLSEKS---ERARKLR Mflv_2696|M.gilvum_PYR-GCK VLRTTF-----AADEAGEPQRTVHDDLLPGWTVQDISELS---EHARRLR MAV_2013|M.avium_104 VLHTTY-----DTTDEGDPRPVLRADLRPEWAEHDLSGLT---EQARRLR MMAR_3691|M.marinum_M ILRTTY-----GVDTEGEPYQVFSDDVEVGWRREDLTRLP---EAGHERQ MUL_3634|M.ulcerans_Agy99 ILRTTY-----GVDTEGEPYQVFSDDVEVGWRREDLTRLP---EAGHEQQ MAB_2122|M.abscessus_ATCC_1997 VLRTVY-----GVDSAGEPYQLFVEEFEVPWTAVDLTDLT---GDAQDRQ MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 LEVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDDGSWR Rv2380c|M.tuberculosis_H37Rv LEVLAQREFCAPFELSRDAPLRITVVRTAADEHVLLLVAHHIAWDDGSWR TH_3141|M.thermoresistible__bu LEVLAQREFTAPFDLSVDSPLRITMIRTGADEHIMLLVAHHIAWDDGSWE Mvan_3845|M.vanbaalenii_PYR-1 LEVLAQREFGRPFDLGAESPLRITVIRTAPAEYVMLLVAHHIAWDDASWE MSMEG_4511|M.smegmatis_MC2_155 LEVLAQREFGTPFDLGTESPLRLTLIRTGPAEHVLLLVAHHIAWDDGSWR Mflv_2696|M.gilvum_PYR-GCK LEVLAQREFGTPFDLATESPLRITVARTAPAEYIMLLVVHHIAWDDGCWR MAV_2013|M.avium_104 LDVLAQRDFRRPFDLSKDSPLRVTAARLADDELMLLITAHHIAWDDGSWA MMAR_3691|M.marinum_M IESLAADEFGRPFDLTNELPLRITVIRTRADELVLLLVVHHICWDDDSWE MUL_3634|M.ulcerans_Agy99 IESLAADEFGRPFDLTNELPLRITVIRTRADELVLLLVVHHICWDDDSWE MAB_2122|M.abscessus_ATCC_1997 VRALADSEFGRPFDLAADRPLRVTLLRLGAEDFVVLLVVHHICWDDNSWE MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 VFFTDLTQAYSRADL-GADLGPEHRPSAASGPDTTEADLNYWRAIMADPP Rv2380c|M.tuberculosis_H37Rv VFFTDLTQAYSRADL-GADLGPEHRPSAASGPDTTEADLNYWRAIMADPP TH_3141|M.thermoresistible__bu VFFDDLTRAYTGVDL-GEELAPQLPP----GPRDPDADLAYWREVLADPP Mvan_3845|M.vanbaalenii_PYR-1 VFFDDLTGAY----V-GEKLRPARRPVVAAGGSD-EDDVAYWRAVMADPP MSMEG_4511|M.smegmatis_MC2_155 VFFTDLTRAYS-----GEQL-PETPRVGAAAPDTTDEDLAYWREVMANPP Mflv_2696|M.gilvum_PYR-GCK VFFADLTRAYT-----GAELGPTPAP--VVEPPTSDEDLRFWRSAMTDLP MAV_2013|M.avium_104 PFFADLTRAYTAPG--DFDATPVVPDLSADPTAIRREDLDYWRPLMADLP MMAR_3691|M.marinum_M VFFGELSAAYNDLPINDPAAQFLSVEVLQNSAAPSVADVGYWAETLRPLP MUL_3634|M.ulcerans_Agy99 VFFGELSAAYNDLPINDPAAQFLSVEVLQNSAAPSVADVGYWAETLRPLP MAB_2122|M.abscessus_ATCC_1997 VFFAELSEYYHGRPVQGEAPQFMVVS--ADTEPSSDADLTYWRRALTPLP MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 EPLELPGPAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLL Rv2380c|M.tuberculosis_H37Rv EPLELPGPAGTCVPTSWRAARATLRLPADTAARVATMAKNTGCTPYMVLL TH_3141|M.thermoresistible__bu EPLELPGPHGSAVPSGWRSARDSVTLGADTARRVVELAQETGCTPYAVLL Mvan_3845|M.vanbaalenii_PYR-1 EPLELPGPTGSAVPTSWRSQRTTLRLDGETARRVTALADEVGATPYAVLL MSMEG_4511|M.smegmatis_MC2_155 EPLELPGPMGSVVPTGFRSQRSTVRLSAETVEKVTVLARETGATPYMVLL Mflv_2696|M.gilvum_PYR-GCK EPLELPGPHGSAVPTTWRCRRVTATLSADTVERVRVAAREAGATPYMVML MAV_2013|M.avium_104 EPLELPGPNGSVVPSTWRAQRAFAELPAEIVDRAAALARETGATPYMVLM MMAR_3691|M.marinum_M EPPELPGVSG--ANPCRRAQRRVRPLPAGLFSRVEDFARKCSASPFMVLL MUL_3634|M.ulcerans_Agy99 EPPELPGVSG--ANPCRRAQRRVRPLPAGLFSRVEEFARKCSASPFMVLL MAB_2122|M.abscessus_ATCC_1997 DPLELPGAAS--TYSSRAARRLAVPMPAETAARIEEFAREHSATPFMVLL MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 AAFGALVHRYTHSDDFLVAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAM Rv2380c|M.tuberculosis_H37Rv AAFGALVHRYTHSDDFLVAAPVLNRGAGTEDAIGYFGNTVAMRLRPQSAM TH_3141|M.thermoresistible__bu AVFGTLIFRYTHADDFLVATPVLNRDSGAEQRIGYYGNTVAMRLRPNAAM Mvan_3845|M.vanbaalenii_PYR-1 AVFGVLIHRYSHVDDFLVATPVLNRNGDTDDVIGYFGNTVAMRLRPHPAM MSMEG_4511|M.smegmatis_MC2_155 AAFGALIRRYTHTDDFLVATPVLNR--DTEDTIGYHGNTVAMRMRPRSDA Mflv_2696|M.gilvum_PYR-GCK AAFGALLHRYTHADDVLIASPVLLRGPDSEDVIGYHGNSAVMRLRPQPMQ MAV_2013|M.avium_104 AAFAALVHRYTGSTDFLVAAPVLNRGAATENVIGYYGNTVVIRLRPQSHQ MMAR_3691|M.marinum_M AAYGVLVRRYTGASDFLVSVPVTERSGAAAGALGYFGNTLLLRITTRSQD MUL_3634|M.ulcerans_Agy99 AAYGVLVRRYTGASDFLVSVPVTERSGAAAGALGYFGNTLLLRITTRSQD MAB_2122|M.abscessus_ATCC_1997 AAFGVLVHRYTGSRDFVTAIPVAERKSNAEKAIGYFGNTLLLRTVVNPDD MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 SFRELLTATRDIASGAFAHQRINLDRVVRELNPDR---RHGAERMTRVSF Rv2380c|M.tuberculosis_H37Rv SFRELLTATRDIASGAFAHQRINLDRVVRELNPDR---RHGAERMTRVSF TH_3141|M.thermoresistible__bu SFRDMLAQSRDTALGAFAHQGINLDRVVRELNPDR---RHGTERMTRVSF Mvan_3845|M.vanbaalenii_PYR-1 TFRDLLTQTRDTALGAFAHQRVGLDRMVRELNPDR---RHGAERMTRVSF MSMEG_4511|M.smegmatis_MC2_155 GFRDLVLQTRDVALGAFAHQRVNLDRVVRELNPDR---RHGAERMTRVSF Mflv_2696|M.gilvum_PYR-GCK TFTELLSRTRDFALDAFAHQQVNLDRVVRELNLDR---RHGAERMTRVSF MAV_2013|M.avium_104 SFRELLAQTRDGAVGAFAHSRADLDWLVRESNPDR---RHGADRMTRVSF MMAR_3691|M.marinum_M TFTSFVNEVRETCLAGFAHQSVGIDRVVREANPER-MGRDGMDLLVRLGF MUL_3634|M.ulcerans_Agy99 TFTSFVNEVRETCLAGFAHQSVGIDRVVREANPER-MGRDGMDLLVRLGF MAB_2122|M.abscessus_ATCC_1997 SFASHVAAVREVCLDAFGHQNVGIDEVVREVNPSRSIGHDGMDELVRLGF MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 GFREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDR-----AGVLVE Rv2380c|M.tuberculosis_H37Rv GFREPDGGGFNPPGIECERYDLRSNITQLPLGFMVEFDR-----AGVLVE TH_3141|M.thermoresistible__bu GFRGPDRFGFTPPGVRCERAELRSHLTQLPLGVMIEFDPDP-ADPGATVE Mvan_3845|M.vanbaalenii_PYR-1 GFRSRDRFGFTPPGVTCERADLRSHLTHLPLGIMVEFDP-----DEVVVE MSMEG_4511|M.smegmatis_MC2_155 GFREPDGGGFCPAGVRCERAELRGNHTQLPLGFMVEWEA-----TGATVE Mflv_2696|M.gilvum_PYR-GCK GFREPDGGGFSPPGVTCRRAELRGQITQLPLGLMVELHE-----SGAVVE MAV_2013|M.avium_104 GQREPDGAGFCPPGVRCERGDLRGHFNQLPLSLMVELNRTPDGSGGGLVE MMAR_3691|M.marinum_M NMR-KSAGGLALDGVVVRQLGLGAVAAHLPLSLTIALDP-----DDVSVE MUL_3634|M.ulcerans_Agy99 NMR-KSAGGLALDGVVVRQLGLGAIAAHLPLSLTIALDP-----DDVSVE MAB_2122|M.abscessus_ATCC_1997 SMR-KDASGYRLEGVDVTQLDLAAVSAQLPLSLAIATES-----SGTIVE MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 AEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDERDAARLR Rv2380c|M.tuberculosis_H37Rv AEHLVEILEPALAKQMLRHFGVLLDNALAAPDNTLSGLALMDERDAARLR TH_3141|M.thermoresistible__bu IEHLVEVIEPALGRQLLRHFVVLLEDALRRPDTPLSRLRLMDDADLAWLR Mvan_3845|M.vanbaalenii_PYR-1 LEHLVEIIEPGLARQLLDHYAVLIRSALDDPDTTLSGLQLMGDDDLEWLR MSMEG_4511|M.smegmatis_MC2_155 AEHLTEVLDAALAEQMLRHFTVLLDNALADPDRALWRLDLFTAEDTAWLT Mflv_2696|M.gilvum_PYR-GCK AEFLVEVLDDTLVTQMLDHYVVLLEAAVAQPDTVLSRLELMDGDDAEWLR MAV_2013|M.avium_104 AEYLVEVLDQQLVEQMLRHYRTLLDSLLSDPDATLSACALMSDADAEWLR MMAR_3691|M.marinum_M FEYQQQLS-SVLVDQMLVHYLQLVDKALAEPERPLSSLDILGAGERDSVL MUL_3634|M.ulcerans_Agy99 FEYQQQLS-SVLVDQMLAHYLQLVDKALAEPERPLSSLDILGAGERDSVL MAB_2122|M.abscessus_ATCC_1997 FEYQTDVLPQWLVGQLLVHYQRLLADGLSRPEETLARLELFDAEEHSALL MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 EVSRGERFDTPVKTLVDLVNEQTTRT--PDATAVVYEGQHFTYHDLNEAS Rv2380c|M.tuberculosis_H37Rv EVSRGERFDTPVKTLVDLVNEQTTRT--PDATAVVYEGQHFTYHDLNEAS TH_3141|M.thermoresistible__bu DVSRGDRFDTPARTLPDLIESQVRQT--PDAVAVVYEGRHYSYRELNEAA Mvan_3845|M.vanbaalenii_PYR-1 AVSVGPTFDTPPATITDLIEAQVRRS--PDGTAVVYEGRHYTYREINEAA MSMEG_4511|M.smegmatis_MC2_155 RMATGEAFDTPAATLTDLVTQQAERT--PDATAVVYEGRHFTYREINESA Mflv_2696|M.gilvum_PYR-GCK RVSHGPEFDVPAATIGELIEARTDLT--PDTVAVVYEGRRYTYREINESA MAV_2013|M.avium_104 AVSTGEQFITPAATLSELVSRRAART--PDAVAVVYEGRTYTYRDIEEES MMAR_3691|M.marinum_M AQSHGELVEMPATTMVKLLEATASAAGTATALALVSDEAELTYSELHRRA MUL_3634|M.ulcerans_Agy99 AQSHGELVEMPATTMVKLLEATASAAGTATALALVSDEAELTYSELHRRA MAB_2122|M.abscessus_ATCC_1997 DQSHGVLTRPSAATLVDLLDAAARAT--PEALAVVSDDVELTYELLQQRS MLBr_00134|M.leprae_Br4923 ---------MRSENLAALLARQAAEAG-WYDKPAYFAPDVVTHGQIHDGA .: *: . : . :: :. : Mb2401c|M.bovis_AF2122/97 NRLGHWLIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAVYVPVDPSYP Rv2380c|M.tuberculosis_H37Rv NRLGHWLIEQGIGSEDRVAVLLDKSPDLIVTALGVVKSGAVYVPVDPSYP TH_3141|M.thermoresistible__bu NRVAHWLIGQGIGTEDRVAVLLDKSPELVITALGVLKAGAVYLPIDPTYP Mvan_3845|M.vanbaalenii_PYR-1 NRVAHWLIGEDVGAEDRVAVMLDKSPELVVTALGVLKAGAVYVPIDPAYP MSMEG_4511|M.smegmatis_MC2_155 NRLAHWLIGQGIGTEDRVAVLLEKSPELVITALGIVKAGAVYLPVDPTYP Mflv_2696|M.gilvum_PYR-GCK NRVAHWLIGQGIGAEDRVAVLMDRSPELLITALGIIKAGAVYLPVDPSYP MAV_2013|M.avium_104 NRVAHWLIERGVGTEDRVAVLLDKSPELVITALGVLKAGGVYLPVDPTYP MMAR_3691|M.marinum_M NRLARWFIGQGFGPEDIIGLRMANSIEFIVAMLAVLKAGAAYLPIDPAYP MUL_3634|M.ulcerans_Agy99 NRLARWFIGQGFGPEDIIGLRMANSIEFIVAMLAVLKAGAAYLPIDPAYP MAB_2122|M.abscessus_ATCC_1997 NRFARWLVAQGAGTEDVIALQMSTSVEFIVAMLGVLKSGAAYMPIDPALP MLBr_00134|M.leprae_Br4923 VRLGEVLRNRGLSAGDRVLLCLPDSPDLVQLLLACLARGIMAFLANPELH *... : .. .. * : : : * ::: *. : * . :* Mb2401c|M.bovis_AF2122/97 QDRLDFILADCDAKLVLR------TPVRELAGYRSD-----DPTDADRIR Rv2380c|M.tuberculosis_H37Rv QDRLDFILADCDAKLVLR------TPVRELAGYRSD-----DPTDADRIR TH_3141|M.thermoresistible__bu DDRLSFILGDCDARLVLR------EPVSDLDGQPTT-----DPTDTDRVR Mvan_3845|M.vanbaalenii_PYR-1 QDRLEFILGDCDAKVVVR------EPVTGLDGYRAD-----DPGDNDRRR MSMEG_4511|M.smegmatis_MC2_155 EDRLNYILSDSDPKIVLR------EFVTGLDDQPTT-----DPTDAERVR Mflv_2696|M.gilvum_PYR-GCK QDRMSFVLSDSDPTLVIR------EPVAGLDGHRTD-----NPTDDVRVR MAV_2013|M.avium_104 QDRLNFILGDADAKLVLR------EPVTDLADYPAT-----APT--ELLR MMAR_3691|M.marinum_M DERIDYLITDARPQTVIG------RPELDVAERAAADNSDLPLSDSDRLR MUL_3634|M.ulcerans_Agy99 DERIDYLITDARPQTVIG------RPELDVAERAAADNSDLPLSDGDRLR MAB_2122|M.abscessus_ATCC_1997 EERIEYLIADAKPRIVMR------PQEFRVAEAAATGLGDAPITDADRLR MLBr_00134|M.leprae_Br4923 RDDYAFPERDTAAALVITNGSLRDRFQSSNVVEPAELLSDATRVEPSDYE : : * . *: : . Mb2401c|M.bovis_AF2122/97 PLRPDNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFK-GEYDVDDTDRL Rv2380c|M.tuberculosis_H37Rv PLRPDNTAYLIYTSGTTGLPKGVAVPHRPVAEYFVWFK-GEYDVDDTDRL TH_3141|M.thermoresistible__bu RLLPGNTAYLIYTSGTTGLPKGVPVPHRPVAEYFVWFK-GDYQVDANDRL Mvan_3845|M.vanbaalenii_PYR-1 PVGPYNTAYLIYTSGSTGLPKGVPVPHRPVAEYFVWFK-GDYRVDAGDRM MSMEG_4511|M.smegmatis_MC2_155 PLRPDNTAYLIYTSGSTGLPKGVPVPHRPIAEYFVWFG-GEYDVTNEDRL Mflv_2696|M.gilvum_PYR-GCK PLRPENAAYLIYTSGSTGQPKGVPVPHRPVAEYFVWFK-DEYEISESDRL MAV_2013|M.avium_104 PLTPQNTAYLIYTSGSTGLPKGVPVPHAPIAEYFVWFG-DEYRIDETDRL MMAR_3691|M.marinum_M PLRPGHLAYVIYTSGSTGRPKGVAVSHHAIAEHVQGFV-AEWTMTAEDRW MUL_3634|M.ulcerans_Agy99 PLRPGHLAYVIYTSGSTGRPKGVAVSHHAIAEHVQGFV-AEWTMTAEDRW MAB_2122|M.abscessus_ATCC_1997 PLLPDNLAYVIYTSGSTGRPKGVAVAHAAIAEHVVSFT-AEWSMTADDRM MLBr_00134|M.leprae_Br4923 PVSGDAYAFATYTSGTTGKPKAAIHRHADPFTFVDAMCRKALRLTPQDIG : *: ****:** **.. * .. : : * Mb2401c|M.bovis_AF2122/97 LQVASPSFDVSIA-EIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGIT Rv2380c|M.tuberculosis_H37Rv LQVASPSFDVSIA-EIFGTLACGARMVIPRPGGLTDIGYLTALLRDEGIT TH_3141|M.thermoresistible__bu LQVASPSFDVSIA-EIFGTLACGARLVIHRPGGLNDIGYLTALLQDEGIT Mvan_3845|M.vanbaalenii_PYR-1 LQVASPSFDISIA-EVFGTLACGARLVIHRPGGLNDIGYLTALLRDEGIT MSMEG_4511|M.smegmatis_MC2_155 LQVASQSFDVSIG-EIFGMLAAGARLVIPKPGGLTDIGYLTDLLRNEGIT Mflv_2696|M.gilvum_PYR-GCK LQVASPSFDVSIG-EIFGTLACGGRLVIPKPDGLTDVAYLTELLQREGIT MAV_2013|M.avium_104 LQVASPSFDVSIG-EIFGTLIMGARLVIPRPDGLRDIGYLTELLAREGIT MMAR_3691|M.marinum_M LQFSSVSFDASLA-DIFVTLFLGAQLIVPKPDAFGDISYVADLISRRGVT MUL_3634|M.ulcerans_Agy99 LQFSSVSFDASLA-DIFVTLFLGAQLIVPKPDAFGDISYVADLISRRGVT MAB_2122|M.abscessus_ATCC_1997 LQSTSVSFDASLA-DILCPLSLGAQLVIPKPNPFSDIGYVADLVRRRGVT MLBr_00134|M.leprae_Br4923 LCSARMYFAYGLGNSVWFPLATGGSAVISSVPVSAES--AAMLSTRFEPS * : * .:. .: * *. :: : : * : Mb2401c|M.bovis_AF2122/97 AMHFVPSLLGLFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALL Rv2380c|M.tuberculosis_H37Rv AMHFVPSLLGLFLSLPGVSQWRTLQRVPIGGEPLPGEVADKFHATFDALL TH_3141|M.thermoresistible__bu AMHFVPSLLGLFLSLPGVNQWRTLQRVPIGGEPLPGEVADKFHATFDALL Mvan_3845|M.vanbaalenii_PYR-1 AMHFVPSLLGLFLSLPGVNQWRTLQRVPIGGEALPGEVADKFRATFDALL MSMEG_4511|M.smegmatis_MC2_155 SMHFVPSLLGLFLSLPGVNEWRTLQRVPIGGEALPGEIADKFHATFDSLL Mflv_2696|M.gilvum_PYR-GCK AMHFVPSLLGLFLSLPGVNQWRTLERVPIGGEALPGELADRFHATFDALL MAV_2013|M.avium_104 SMHFVPSLLGLFLSLPGVSQWRTLRRVPIGGEALPGEIADKFHATFDASL MMAR_3691|M.marinum_M VLHLVPSMLSTLLLLPQVQQWRQLRHVPVGGEALPGEVADRFAGYFDAEL MUL_3634|M.ulcerans_Agy99 VLHLVPSMLSTLLLLPQVQQWRQLRHVPVGGEALPGEVADRFAGYFDAEL MAB_2122|M.abscessus_ATCC_1997 VLHMVPSLLGSVLLLPEARELRGLRHVPVGGEALPGEVADKFATMFDAEL MLBr_00134|M.leprae_Br4923 VLYGVPSFFARVVGACSPDSFRSLRCVVTAGEALEPALAERLVEFFGGIP :: ***::. .: . * *. * .**.* :*::: *.. Mb2401c|M.bovis_AF2122/97 HNFYGPTETVINASRFKVVGPQGTRIVPIGRPKINTTMHLLDDSLQPVPT Rv2380c|M.tuberculosis_H37Rv HNFYGPTETVINASRFKVVGPQGTRIVPIGRPKINTTMHLLDDSLQPVPT TH_3141|M.thermoresistible__bu HNFYGPTETVINASRYKVEGKQGTRIVPIGRPKINTQLHLLDNALQPVPV Mvan_3845|M.vanbaalenii_PYR-1 HNFYGPTETVINATRFKVEGRQGTRIVPIGKPKINTAIHILDDALQPVPV MSMEG_4511|M.smegmatis_MC2_155 HNFYGPTETVLNCTRYKVEGKQGARTVPIGKPKINTTIHLLDDALQPVPV Mflv_2696|M.gilvum_PYR-GCK HNFYGPTETIINTTRYKVEGTQGSRIVPIGTPKINTTVHLLDDALRPVPV MAV_2013|M.avium_104 YNFYGPTETVVNCTSYPVEGAQGTRVVPIGRPKINTRVYLLDNALQPVPP MMAR_3691|M.marinum_M RNHYGPTEAVVCSTHMVVTGSHGARVVPIGVPNRNVYAYVLDEQLHPVPD MUL_3634|M.ulcerans_Agy99 RNHYGPTEAVVCSTHMLVTGSHGARVVPIGVPNRNVYAYVLDEQLHPVPD MAB_2122|M.abscessus_ATCC_1997 RNHYGPTEAVVCSTYMSVRGPQGNSIVPIGRPNQNVYAYVLDQALKLVPA MLBr_00134|M.leprae_Br4923 --ILDGIGSSEVGQTFVSNSVDDWRVGTLGKVLPPYEIRVVAPDGATAGS . : . .. .:* :: . Mb2401c|M.bovis_AF2122/97 GVIGEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRMYRSGDLARRNA Rv2380c|M.tuberculosis_H37Rv GVIGEIYIGGTHVAYGYHRRAGLTAERFVADPFNPGSRMYRSGDLARRNA TH_3141|M.thermoresistible__bu GVIGEIYIGGTHVAHGYHRRPGLTAERFVADPFNPGGRLYRSGDLARRNA Mvan_3845|M.vanbaalenii_PYR-1 GSIGEIYIGGTHVARGYHHRPGLTAERFVADPFTPGARMYRSGDLARRNA MSMEG_4511|M.smegmatis_MC2_155 GVIGEIYIGGTHVAHGYHRRPGMTAERFVADPFNPGGRMYRSGDLARRNA Mflv_2696|M.gilvum_PYR-GCK GAIGEIYIGGGHVARGYHRRPALTAERFVADPFTVGGRLYRSGDLARRNA MAV_2013|M.avium_104 GVIGEIYIAGTHVAHGYHRRPQLTAERFVADPFSRGGRMYRSGDLARRNA MMAR_3691|M.marinum_M QVIGELYLGGSQLARGYLGRPTLTAQRFIADPFNPGMRLYRTGDLVRRNH MUL_3634|M.ulcerans_Agy99 QVVGELYLGGSQLARGYLGRPTLTAQRFIADPFNPGMRLYRTGDLVRRNH MAB_2122|M.abscessus_ATCC_1997 GVVGELYLGGAQLARGYRARPVLTAERFVADPFGSGGRLYRTGDLVRRNA MLBr_00134|M.leprae_Br4923 GIEGNLWVRGPSIAQSYWNRP---------DSLLENGDWLNTRDRVRIDG *:::: * :* .* *. *.: . .: * .* : Mb2401c|M.bovis_AF2122/97 DGDIEFVGRADEQVKIRGFRIELGDVAAAIAVDPTVGQAVVVVSDLPRLG Rv2380c|M.tuberculosis_H37Rv DGDIEFVGRADEQVKIRGFRIELGDVAAAIAVDPTVGQAVVVVSDLPRLG TH_3141|M.thermoresistible__bu DGDIEFVGRADEQVKIRGFRIELGDVAAAISVDPSVGQAVVVATDLPNVG Mvan_3845|M.vanbaalenii_PYR-1 DGDIEFVGRADEQVKIRGFRIELGDVAAAITVDPSVGQAVVVVSDLPNLG MSMEG_4511|M.smegmatis_MC2_155 DGDIEFVGRADEQVKIRGFRIELGEVSAAISVDPSVGQAVVVVSDLPSLG Mflv_2696|M.gilvum_PYR-GCK DGDLEFVGRADDQVKIRGFRIELGEVAAAISVDPSVGQAVVLGQDLPGLG MAV_2013|M.avium_104 NGDIEFVGRADEQVKIRGFRIELGEIAAAISVDPSVGQAVVLAMDLPQLG MMAR_3691|M.marinum_M CGELEFVGRADEQVKIRGFRIELGEVESVITTHPAVRHCLV-VAEETEAG MUL_3634|M.ulcerans_Agy99 CGELEFVGRADEQVKIRGFRIELGEVESVITTHPAVRHCLV-VAEETEAG MAB_2122|M.abscessus_ATCC_1997 RGELEFVGRADEQVKVRGYRIELGEIEAVIGADPRVGHCVATVVDDPQVG MLBr_00134|M.leprae_Br4923 DGWVTYGCRADDTEIVGGVNINPREVERLIIEADAVAEAAVVGVREFTGA * : : ***: : * .*: :: * * .. . . Mb2401c|M.bovis_AF2122/97 KSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYMLPAAYVVLDEIP Rv2380c|M.tuberculosis_H37Rv KSLVGYVTPAAGGDGPADVGVDLDRIRARVAAALPEYMLPAAYVVLDEIP TH_3141|M.thermoresistible__bu RSLVGYLTPVSG---ESTDSVAVERIRARVAAALPEYMVPAAYVVLDEIP Mvan_3845|M.vanbaalenii_PYR-1 KSLVAYLTPADG------AGVDVDRIRTRVAAALPEYMTPAAYVVVDEIP MSMEG_4511|M.smegmatis_MC2_155 KSLVAYITPAAG-----ADHVDIERIRARVTAALPEYMVPAAYVELDEIP Mflv_2696|M.gilvum_PYR-GCK MSLVGYVTPAAG------EDVDLARVRERVAAALPDYMTPAGYVVLDEIP MAV_2013|M.avium_104 KSLVGYVTPAQG---AGTETVDVERIRARVAAALPDYMTPAAYVVLDEIP MMAR_3691|M.marinum_M PMLAAYLVPA-------AAQVDLEEIRAHTAAAVPEYMVPGAFAVIPEIP MUL_3634|M.ulcerans_Agy99 PMLAAYLVPA-------AAQVDLEEIRAHTAAAVPEYMVPGAFAVIPEIP MAB_2122|M.abscessus_ATCC_1997 SLLAAYVVPAGG-----TREIDLDELRARAQEALPAYMVPTAFAVIPEIP MLBr_00134|M.leprae_Br4923 STLQAFLVPAVG---AFIDESVMRDVHRRLLTQLTAFKVPHRFAIIERLP * .::.*. : :: : :. : * :. : .:* Mb2401c|M.bovis_AF2122/97 ITAHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGR-DRVGA Rv2380c|M.tuberculosis_H37Rv ITAHGKIDRAALPEPQIASDTEFRAPQTATERRLAQLFGELLGR-DRVGA TH_3141|M.thermoresistible__bu ITTHGKIDRAALPEPQIASMIEYREPATDTEREVARLFGDLLGRSERIGA Mvan_3845|M.vanbaalenii_PYR-1 ITAHGKIDRAALPEPEIAPTTEFREPAAGTEAHLAQLFAELLGH-EKVGA MSMEG_4511|M.smegmatis_MC2_155 ITTHGKIDRRALPEPEITSTTRFREPSTDTERTVAGLFAELLER-DEVGA Mflv_2696|M.gilvum_PYR-GCK ITAHGKIDRAALPLPEITTATDYREPQTETEQHLAQLFSELLGV-ARVGV MAV_2013|M.avium_104 ITAHQKIDRAALPQPQIGAGTEYRDPTTPTEHRIAQLFSGLLGH-ERVGV MMAR_3691|M.marinum_M MTVSGKLDRRALPAPTPIATRRYREPETATERWICSIFAQLFGR-QRVGA MUL_3634|M.ulcerans_Agy99 MTVSGKLDRRALPAPTPIATRRYREPETATERWICSIFAQLFGR-QRVGA MAB_2122|M.abscessus_ATCC_1997 LTTSGKLDKRALPTPDALTERAFRLPVTPTERRMCAIYSHLFGK-ERVGL MLBr_00134|M.leprae_Br4923 RSTNGKLLRNVLR------------------------------------- :. *: : .* Mb2401c|M.bovis_AF2122/97 DDSFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFEFATVTALAG----- Rv2380c|M.tuberculosis_H37Rv DDSFFDLGGHSLLATKLVAAVRNAFGVDVGVREIFEFATVTALAG----- TH_3141|M.thermoresistible__bu DDSFFDLGGHSLLATKLVAAVRSAFGVDIGVQDVFELGTVARLAG----- Mvan_3845|M.vanbaalenii_PYR-1 DDSFFDLGGHSLLATKLVAELRAGFGVDVEVRDIFENATIARLAA----- MSMEG_4511|M.smegmatis_MC2_155 DDSFFDLGGHSLLATKLVAAVRARCAVDVGVQDVFEHATVSGLAA----- Mflv_2696|M.gilvum_PYR-GCK DDSFFELGGHSLLATKLVSAVRSRCGVDMEIREIFELGTVARLAE----- MAV_2013|M.avium_104 DDSFFDLGGHSLVATKLVTAIRAECGVEIGIRDVFELATVGLLAE----- MMAR_3691|M.marinum_M EDSFFGLGGHSLLAARLVAQIRAEFGVDLTVRTIFDAPTPAGLAARLVER MUL_3634|M.ulcerans_Agy99 EDSFFGLGGHSLLAARLVAQIRAEFGVDLTVRTIFDVPTPAGLAARLVER MAB_2122|M.abscessus_ATCC_1997 DDSFFELGGHSLLAARLVAQIRAQFGIDLTVRAVFDRPTPAGLAEQLVTY MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 -------HIDTLDSDS----------ARPRLTRVDHDGPVRLSSSQMRSW Rv2380c|M.tuberculosis_H37Rv -------HIDTLDSDS----------ARPRLTRVDHDGPVRLSSSQMRSW TH_3141|M.thermoresistible__bu -------RIDELRSGSG-------GPLRPRLTPQHFDGPAPLSSSQLRSW Mvan_3845|M.vanbaalenii_PYR-1 -------HLDTMGRATI-------GTRRPRLVAAPLDGPAPLSSSQLRSW MSMEG_4511|M.smegmatis_MC2_155 -------HIEDLVASGA-------SSGRPAIVAVPHDGPLQMSAAQLRQW Mflv_2696|M.gilvum_PYR-GCK -------RVDELAAGGS-------APLRPRLLAVPHDGPAPMSAAQLRQW MAV_2013|M.avium_104 -------RVDQLSSGEL-------TGTRPKLIATAHDEPLPLSASQLRSW MMAR_3691|M.marinum_M FRNDFELDLDNLAADD---MPLDPKRARPGFVKSARPQRLPLSHSQLAAW MUL_3634|M.ulcerans_Agy99 FRNDFELDLDNLAADD---MPLDPKQARPGFVKSARPQWLPLSHSQLAAW MAB_2122|M.abscessus_ATCC_1997 FREEFEIELDELDLDESDEMEAAPQDGRPDLVAAERPERLPLSSSQLSMW MLBr_00134|M.leprae_Br4923 -------------------------------AQSPTKPIWELSLTESQSA :* :: Mb2401c|M.bovis_AF2122/97 FNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEILRTVYREI Rv2380c|M.tuberculosis_H37Rv FNYRFDGPNAVNNIPFAAALHGPCDTNAFAAAITDVVARHEILRTVYREI TH_3141|M.thermoresistible__bu FAYRVDGPSVVNNIPFAARLHGPVDVDALEAAIGDVIARHEILRTVYREI Mvan_3845|M.vanbaalenii_PYR-1 FGYRIEGRSPVNNIPFAARLTGPCDVDAFVAAIRDVVERHAILRTTYREI MSMEG_4511|M.smegmatis_MC2_155 FQFRIDGPNPVNNVPFAARLSGPCDVDALIAAVGDVVARHEILRTTYREI Mflv_2696|M.gilvum_PYR-GCK FQYRIEGPGPVNNVPFAARFAGPCDVDALIEAVRDVVNRHESLRTTFCEI MAV_2013|M.avium_104 FAYRMDGPSPVNNIPFAARLTGPWDIDALIAAVGDVVARHEILRTRYVEL MMAR_3691|M.marinum_M FQYRIEGAREEFNMPLALRFEGPLDSVALAAALNDVVARHEALRTNFDEH MUL_3634|M.ulcerans_Agy99 FQYRIEGAREEFNMPLALRFEGPLDSVALAAALNDVVARHEALRTNFDEH MAB_2122|M.abscessus_ATCC_1997 FECQMEGVTDIGNMWLALRFDGPLQTPALIAALNDVVARHEALRTNIAIH MLBr_00134|M.leprae_Br4923 TKAQLDGR--------------PASNAHAQAAVGHAAG------------ :.:* * . *: .. Mb2401c|M.bovis_AF2122/97 GGVPHQIIQPPAE-VPVRCAAGSDAAWLRAELNNERGYVFDLETDWPIRA Rv2380c|M.tuberculosis_H37Rv GGVPHQIIQPPAE-VPVRCAAGSDAAWLRAELNNERGYVFDLETDWPIRA TH_3141|M.thermoresistible__bu DGVPYQIVLPTEP-VPVRRADGQGEQWLRAELDAERRHVFDLENERPIRP Mvan_3845|M.vanbaalenii_PYR-1 DGVPYQIVNPISD-VPVRRARGEGEQWLQAELDRERKHTFDLEEDWPIRA MSMEG_4511|M.smegmatis_MC2_155 DGAPYQIIHPPAP-VPVRQARGDGEDWVQAQLDAERRYCFDLETDWPIRA Mflv_2696|M.gilvum_PYR-GCK DGVPYQLVNAPDPGFPVRRDSGPDDAWLVGALDDERRRVFDLENQWPIRV MAV_2013|M.avium_104 DGVPYQVVGPPGVEIPVRREDGPDDPWLQQQLDAERRHCFELDGELPIRV MMAR_3691|M.marinum_M EGVPYQIVHPSRTVQLAVRAIDQDE--FDDVSTQLRRHVFTPESGPLLQA MUL_3634|M.ulcerans_Agy99 EGVPYQIVHPSRTVQLAVRAIDQDE--FDDVSTQLRRHVFTPESGPLLQA MAB_2122|M.abscessus_ATCC_1997 EGAPYQIVHPSRELAVPILRSSPEG--LSDTLAELRHHIFGLETESLIRP MLBr_00134|M.leprae_Br4923 -------------------------ATLKQRLSALQQERERLVVEAVCAE . : Mb2401c|M.bovis_AF2122/97 ALLSTP-----------------------EQTVLSLVVHHIAGDHWSAGV Rv2380c|M.tuberculosis_H37Rv ALLSTP-----------------------EQTVLSLVVHHIAGDHWSAGV TH_3141|M.thermoresistible__bu AILSLRPDAGSPDS------------PAGDVHVLSLVMHHIAGDHWSATV Mvan_3845|M.vanbaalenii_PYR-1 AVFTVGAVSPASDGGAVSPASDGGAVDPASDHVLSVVIHHIAGDHWSGGV MSMEG_4511|M.smegmatis_MC2_155 AVLTTA-----------------------EHHVLSLVVHHIAADHWSGTV Mflv_2696|M.gilvum_PYR-GCK AVLSIP-----------------------GEHALSVVVHHIAADHWSGGV MAV_2013|M.avium_104 AVLRVAN---------------------AAEHVLSLVVHHIASDHWSAGV MMAR_3691|M.marinum_M NLLVLG----------------------PDTHVLLLIVHHIVSDHASLEI MUL_3634|M.ulcerans_Agy99 NLLVLG----------------------PDTHVLLLIVHHIVSDHASLEI MAB_2122|M.abscessus_ATCC_1997 AIIELS----------------------AQEHVLALVVHHIVVDHASFTV MLBr_00134|M.leprae_Br4923 AVKMLG------------------------ESDPGLINRDLAFSDLGFDS : :: :.:. .. . Mb2401c|M.bovis_AF2122/97 LFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSALLDDGAG----IVG Rv2380c|M.tuberculosis_H37Rv LFTDLLTAYRARSTGQRPSWAPLPVQYADYSVWQSALLDDGAG----IVG TH_3141|M.thermoresistible__bu LFTDLLTAYRARTAGQEPAWAPLPVQYADFGAWESELLAEETG----IAG Mvan_3845|M.vanbaalenii_PYR-1 LFTDLVAAYRARKAGERPTWAPLPVQYTDYGAWQAELLSDDTG----IAG MSMEG_4511|M.smegmatis_MC2_155 LFTDLLTAYHARHAGSAVELPPLPVQYADFAAWQAELLAGTDD----TID Mflv_2696|M.gilvum_PYR-GCK LFTELLTAYRARRAGEAPTWAPLPVQYADYAAWQSALLADDSG----IVA MAV_2013|M.avium_104 LFADVMTAYRARRGGEAPSWAPLRVQYADYAAWQRTFLGDAGGQESAVAG MMAR_3691|M.marinum_M VFDDLIVAYRARLQHNAPQWDILPIQFADYAVWQRNTFESN------WGQ MUL_3634|M.ulcerans_Agy99 VFDDLIVAYRARLQHNAPQWDILPIQFADYAVWQRNTFESN------WGQ MAB_2122|M.abscessus_ATCC_1997 IVDDLIAAYRARLEGQAPQWDPQPVQYADYVLWQRDAFAPDSE----FGQ MLBr_00134|M.leprae_Br4923 QMTVTLCNRLAVVTG---------LRLPETVGWDYGSISGLSR------- . : * :: .: *: : Mb2401c|M.bovis_AF2122/97 PQRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAIRDKLAA Rv2380c|M.tuberculosis_H37Rv PQRDYWIRQLGGLAGETGLRPDFPRPALLSGAGDAVEFRLGAAIRDKLAA TH_3141|M.thermoresistible__bu PQREYWTRQLAGLPEETGLRPDFPRPPVPSGLAEAVEFTIDAAVREKLAG Mvan_3845|M.vanbaalenii_PYR-1 PQREYWIRQLADAPVESGLPLEFSRPRLPSGKGDAVEFTIDGQVRRQITE MSMEG_4511|M.smegmatis_MC2_155 EQRRYWTTQLAGLPEENGLYPDFPRPPVPTGDGAALDFSIDADTRARLIA Mflv_2696|M.gilvum_PYR-GCK AQRRYWTQQLEGLSAETGLQPDLVRPSVPSGAADAVEFTLDAAIREKLVT MAV_2013|M.avium_104 AQREYWTRQLAGLPEDTGLRPDFPRQPVPSGDGESVDFHIDAATRAKLAD MMAR_3691|M.marinum_M TELDYWRDALAGLPDEISVATDRARPRVLGKRGEVVQFSVPAARRAALTQ MUL_3634|M.ulcerans_Agy99 TELDYWRDALAGLPDEISVATDRARPRVLGKRGEVVQFSVPAARRSALTQ MAB_2122|M.abscessus_ATCC_1997 AEVNFWRQQLAGVPTEIAVAHDRARPQILGKRGEVAKFVMEPERRQALTR MLBr_00134|M.leprae_Br4923 ----YLEAELSGVRS----RPETPLSANSGAKG--------------LSP : * . : . : Mb2401c|M.bovis_AF2122/97 VSRDLGVTEFMLLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANLDQLIGF Rv2380c|M.tuberculosis_H37Rv VSRDLGVTEFMLLQAAVAVVLHKAGGGVDVPIGAPVAGRSEANLDQLIGF TH_3141|M.thermoresistible__bu LCRDLGITEFMALQAAVAVVLHKAGSGSDIPLGTPVAGRSEPELDQLVGF Mvan_3845|M.vanbaalenii_PYR-1 LCRELGITEFMLLQAAVAVTLAKVGGGLDIPLGTPVAGRSEAELEQLVGF MSMEG_4511|M.smegmatis_MC2_155 LTRELGVTEFMLLQAAVAIALHKSGQGTDIPLGTPVAGRTAPELDALIGF Mflv_2696|M.gilvum_PYR-GCK LSREVGATEFMLLQAAVAVTLYKAGEGPDIPLGTPVAGRTESELDQLIGF MAV_2013|M.avium_104 VCRELGITEFMLLQTAVAVVLHKAGGGVDIPLGTPVAGRTEAELDQLIGF MMAR_3691|M.marinum_M LAERNGATEFMLYQAALAVVLHKLGGGTDIALGSPVAARVEPATAQLVGL MUL_3634|M.ulcerans_Agy99 LAERNGATEFMLYQAALAVVLHKLGGGTDIALGSPVAARVEPATAQLVGL MAB_2122|M.abscessus_ATCC_1997 MAEQRGVTEFMVYQAALAVVLHRLGGGTDIVIGSPVAARVHPHVAKLVGL MLBr_00134|M.leprae_Br4923 IDEELKKVEEMV-----------------VAIGASEKQRVADRLRALLGI : . .* * : :*:. * *:*: Mb2401c|M.bovis_AF2122/97 FINIVVLRNDLRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVEAVNPQR Rv2380c|M.tuberculosis_H37Rv FINIVVLRNDLRGNPTLREVLQRTRQMALAAYAHQDLPFDQVVEAVNPQR TH_3141|M.thermoresistible__bu FINILVLRNDLSGNPSLREVCRRAREMALAAYAHQDLPFDQVVDAVSPVR Mvan_3845|M.vanbaalenii_PYR-1 FVNFVVLRNDLRGNPTLREVLIRAREMALSAYSNQDVPFEQVVEAVNPPR MSMEG_4511|M.smegmatis_MC2_155 FINIVVLRNDLSGNPSLREVLRRSREMALAAYQHQDLPFDRVVDAVSPVR Mflv_2696|M.gilvum_PYR-GCK FINILVLRNDLRDNPSLRDVGFRSREMALAAYAHQDLPFDQVVDAVSPVR MAV_2013|M.avium_104 FVNILVLRNDLDGNPTLRELLKRARETALAAYAHQDLPFDRVVDSVSPVR MMAR_3691|M.marinum_M FANVVVLRTDLSGDPTLRSILVGSRDTVLDALAHQELPIERLVEALNPPR MUL_3634|M.ulcerans_Agy99 FANVVVLRTDLSGDPTLRSILVGSRDTVLDALAHQELPIERLVEALNPPR MAB_2122|M.abscessus_ATCC_1997 FANMVALRNDLSGDPSLRSVLERSRDATLNAHAHQELPIEKLVEAVNPVR MLBr_00134|M.leprae_Br4923 IVDGEAGLSKRIQAASTPDEIFQLIDSELCE------------------- : : . .. .: . : * Mb2401c|M.bovis_AF2122/97 SLSRNPLFDIVVHVREQMPQDHVIDTGPDG----DTTLRVLEPTFDAAQA Rv2380c|M.tuberculosis_H37Rv SLSRNPLFDIVVHVREQMPQDHVIDTGPDG----DTTLRVLEPTFDAAQA TH_3141|M.thermoresistible__bu TLARNPLFSVVVHVREQLPENRVIDHGPDG----DTTVTVLEPPFDAAHA Mvan_3845|M.vanbaalenii_PYR-1 TLARNPLFQVVVHVREQLPQRQMIDT--------DTEFTALEPTFDIAQA MSMEG_4511|M.smegmatis_MC2_155 SLSRNPLFGVVVHVRDDLPADQVIDDGGNG----ETRFTALEPTFDVAHA Mflv_2696|M.gilvum_PYR-GCK SLSRNPLFGVVVHVREELPQDRVIATGSDG----ETTFTALEPTFDMAHA MAV_2013|M.avium_104 SLSRNPLFQVVVHVRDHLSATRVIETAPVGGDGQDTVCTSLDPVFDMAHA MMAR_3691|M.marinum_M ALSRNPLFQNMLNFRGEDWALVPRDLTGRG----ETTVVPLPVNFEVALL MUL_3634|M.ulcerans_Agy99 ALSRNPLFQNMLNFRGEDWALVPRDLTGRG----ETTVVPLPVNFEVALL MAB_2122|M.abscessus_ATCC_1997 SLSWNPLFQTMVNFRGADWGTAARDVTVSG----ETTVVPLPMEVDVSYL MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 DLSVNFFA-------CGD--EYRGHVIYRTELYERATAQRFADWLVRVVE Rv2380c|M.tuberculosis_H37Rv DLSVNFFA-------CGD--EYRGHVIYRTELYERATAQRFADWLVRVVE TH_3141|M.thermoresistible__bu DLSLNFFA-------AEDGGGYRGHVIYRPELYSRDTAQRFADWLGRVVT Mvan_3845|M.vanbaalenii_PYR-1 DLSLNFLA-------DGT--GYRGYLIYRPELYARRTIERLGRWLPRVVA MSMEG_4511|M.smegmatis_MC2_155 DLSLNFFAQNGNGGRAGEPAGYKGTVIYRTELYEPATARRLIGWLHRIID Mflv_2696|M.gilvum_PYR-GCK DLSVNFFA-------GGN--GYRGHVIYRTELYTRATAERFAGWLSAVIT MAV_2013|M.avium_104 DLSVNFFG-----TDGAGDIGYNCHLIFRTDLYRRTTIERLAGWLVRAVT MMAR_3691|M.marinum_M FLAIGMSV--------TPSGELDVQVIANADLYEPATVALIADALDAALA MUL_3634|M.ulcerans_Agy99 FLAIGMSV--------TPSGELDVQVIANADLYEPATVALIADALDAALA MAB_2122|M.abscessus_ATCC_1997 DLNFALNV--------TPSGGLDVSVVANADLYDHETTRMIAQALDTAFD MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 AFADRPDQPLREVEMVSAQARRRILDRSNAGAGT---------------- Rv2380c|M.tuberculosis_H37Rv AFADRPDQPLREVEMVSAQARRRILDRSNAGAGT---------------- TH_3141|M.thermoresistible__bu AFAERPDITLRELEIGAPGERRRILEEWGGGT------------------ Mvan_3845|M.vanbaalenii_PYR-1 AFVDTPDRALGDVDIVSAEERQRVSQEWSTGAR----------------- MSMEG_4511|M.smegmatis_MC2_155 AFATDADTTLRDIAVIDADERTLLIEDWSRRAVPPA-------------- Mflv_2696|M.gilvum_PYR-GCK AFADDPERHVDDVVIAEPVRPGDGAEA----------------------- MAV_2013|M.avium_104 AFADDLDQTLRDVALIDAGEQQRILRQWSRGAQPPRDRPRTIPELLQASR MMAR_3691|M.marinum_M AFATTPDLPLSAVQLLPSADLAK--------------------------- MUL_3634|M.ulcerans_Agy99 AFATTPDLPLSAVQLLPRADLAK--------------------------- MAB_2122|M.abscessus_ATCC_1997 AFVNNQESRVSEIVLLPADAMAQ--------------------------- MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 -------------------------------------------------- Rv2380c|M.tuberculosis_H37Rv -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_4511|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2013|M.avium_104 SLGADRIAVRCGAEHIDYPALHRRSDNLAALLVDRGVGPGTLVGLSTRRS MMAR_3691|M.marinum_M -------------------------------------------------- MUL_3634|M.ulcerans_Agy99 -------------------------------------------------- MAB_2122|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 -------------------------------------------------- Rv2380c|M.tuberculosis_H37Rv -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_4511|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2013|M.avium_104 IELVVALVAIMKAGAGYFPVDPGYPSARKQFMLDDVRPPVVVATVEAVDT MMAR_3691|M.marinum_M -------------------------------------------------- MUL_3634|M.ulcerans_Agy99 -------------------------------------------------- MAB_2122|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 -------------------------------------------------- Rv2380c|M.tuberculosis_H37Rv -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_4511|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2013|M.avium_104 MPGLPGVELLSLDDPQVRALVDRDDVDPRAGRLRPPHPDDPMYLVFTSGS MMAR_3691|M.marinum_M -------------------------------------------------- MUL_3634|M.ulcerans_Agy99 -------------------------------------------------- MAB_2122|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 -------------------------------------------------- Rv2380c|M.tuberculosis_H37Rv -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_4511|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2013|M.avium_104 TGKPKGAVGTHRSMAARLDWQLRHYPPRTDDVRLAQASITFLEGGMEMLA MMAR_3691|M.marinum_M -------------------------------------------------- MUL_3634|M.ulcerans_Agy99 -------------------------------------------------- MAB_2122|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 -------------------------------------------------- Rv2380c|M.tuberculosis_H37Rv -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_4511|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2013|M.avium_104 GLAAGATMILADDAEHRDPEALGELMHRHSVAQVTAVPSLVSALLDSRPD MMAR_3691|M.marinum_M -------------------------------------------------- MUL_3634|M.ulcerans_Agy99 -------------------------------------------------- MAB_2122|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 -------------------------------------------------- Rv2380c|M.tuberculosis_H37Rv -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_4511|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_2013|M.avium_104 AVRSLSRLVCGGEPVSTSLLQRLVSVCDEADGGGPELLNNIGSTETSGAV MMAR_3691|M.marinum_M -------------------------------------------------- MUL_3634|M.ulcerans_Agy99 -------------------------------------------------- MAB_2122|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 ------------------ARVYLLDDALKPVPVGVVGDVYYGGGPAVGAR Rv2380c|M.tuberculosis_H37Rv ------------------ARVYLLDDALKPVPVGVVGDVYYGGGPAVGAR TH_3141|M.thermoresistible__bu --------------------VYVLDETLQPVPVGVVGDVYTAGPALAAAH Mvan_3845|M.vanbaalenii_PYR-1 --------------------VQVLDADLAPAPVGVFGDLYLSGG------ MSMEG_4511|M.smegmatis_MC2_155 -----------LPQTEGATNVYVLDEWLEPVAIGVIGDVYYAGGAVDASA Mflv_2696|M.gilvum_PYR-GCK ---------------------VLLDGAGHPVPVGVVADVHYAGAPDRRGD MAV_2013|M.avium_104 SRGPLSPPNPLVGKPVPGAQAYLLDDGLRPVPVGVVGELYYAGDQLARGY MMAR_3691|M.marinum_M -------------------------------------------------- MUL_3634|M.ulcerans_Agy99 -------------------------------------------------- MAB_2122|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 LARPSETA-------------TRFVADPFAAQPGSRLYRNGER------- Rv2380c|M.tuberculosis_H37Rv LARPSETA-------------TRFVADPFAAQPGSRLYRNGER------- TH_3141|M.thermoresistible__bu WTRAGVTA-------------TRLVADPVGNRPGARLYRTGDR------- Mvan_3845|M.vanbaalenii_PYR-1 ---------------------------PFAQR-----HRTGDR------- MSMEG_4511|M.smegmatis_MC2_155 EAANGVAA-------------QRFVPNPFGAG---RLYRTGDR------- Mflv_2696|M.gilvum_PYR-GCK RARWTEDGRLQYVERVDHDLEAALAAVPGVAAAAVRTWEIGHRTAVVGYV MAV_2013|M.avium_104 WKRPGLTA-------------ARFVANPFGAEPGSRLYRSGDL------- MMAR_3691|M.marinum_M -------------------------------------------------- MUL_3634|M.ulcerans_Agy99 -------------------------------------------------- MAB_2122|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 ---------GVWKADGQLELL-------------AEIERLPTAQAAP--- Rv2380c|M.tuberculosis_H37Rv ---------GVWKADGQLELL-------------AEIERLPTAQAAP--- TH_3141|M.thermoresistible__bu ---------ARWIADGVLEFVD------------AQPPTIPAVRPDSG-- Mvan_3845|M.vanbaalenii_PYR-1 ---------ARWDDDGRLEIA-------------ARAPGATVVEVAPP-- MSMEG_4511|M.smegmatis_MC2_155 ---------ARWTPDGRLEPVT------------AGEPRLQAALEAVDGV Mflv_2696|M.gilvum_PYR-GCK VPAEPVDDPASFAETVRAAVAP------------ESAPTSITVLDALPAT MAV_2013|M.avium_104 ---------ARWTEDGQLEFVGRSDHQVQVRGFRVELAEVEAALAGADGV MMAR_3691|M.marinum_M ----------------------------------LLAPPLPAGPAASP-- MUL_3634|M.ulcerans_Agy99 ----------------------------------LLAPPLPAGPAASQ-- MAB_2122|M.abscessus_ATCC_1997 ----------------------------------LMAPPAAAVEPVTT-- MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 -------------------------------------------------- Rv2380c|M.tuberculosis_H37Rv -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_4511|M.smegmatis_MC2_155 AAAATRYWENRSAPLLAAYVVADAAHAADPQFAEQVRTALPDEFAGAA-- Mflv_2696|M.gilvum_PYR-GCK R------------------------------------------------- MAV_2013|M.avium_104 AAAAARTWEVHGGTSLAGYVVPQRPIADEAEKAAFAAQVRAEIAATLPGY MMAR_3691|M.marinum_M -------------------------------------------------- MUL_3634|M.ulcerans_Agy99 -------------------------------------------------- MAB_2122|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 ---------------------------------VPAEPADTETERALAAI Rv2380c|M.tuberculosis_H37Rv ---------------------------------VPAEPADTETERALAAI TH_3141|M.thermoresistible__bu --------------------------------QRPGGPPATDTERALATL Mvan_3845|M.vanbaalenii_PYR-1 --------------------------------AVEFEEPRTDSERALAAL MSMEG_4511|M.smegmatis_MC2_155 -----------ITVVDDLTPAALTRPRVSATASGPFEAPATPTERAVAAM Mflv_2696|M.gilvum_PYR-GCK ------------------------RALPAPRVGGPSEPARTDTEKALVGM MAV_2013|M.avium_104 MMPSSLTVLDALPKTESGKLNRPGLPRPAVSTGGRTEPARTDTERALANV MMAR_3691|M.marinum_M ----------------------------------PVAAGSAETERRLTAM MUL_3634|M.ulcerans_Agy99 ----------------------------------PVAAGSAETERRLTAM MAB_2122|M.abscessus_ATCC_1997 ----------------------------------PSVEGSEETKLVLISI MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 LADVLEVGEVG----RYDDFFNLGGDSILATQVAARARDGGIPLTARMVF Rv2380c|M.tuberculosis_H37Rv LADVLEVGEVG----RYDDFFNLGGDSILATQVAARARDGGIPLTARMVF TH_3141|M.thermoresistible__bu LAEVLDTEVTG----RDDDFFSLGGDSILAVQLAARARDTGLKLTARMVF Mvan_3845|M.vanbaalenii_PYR-1 LSELLATEEVG----RHDDFFGLGGDSVLAVQLAARARDTGLDLTARMVF MSMEG_4511|M.smegmatis_MC2_155 LVELLGVTQVG----RHDDFFTLGGDSILAVQLAARARDAGVAMTARMVF Mflv_2696|M.gilvum_PYR-GCK LADVLVEVHDGTGIGRFDDFFELGGDSILAVQLAARAKQAGLRLSARMVF MAV_2013|M.avium_104 FAELLSTPEVG----RFDDFFALGGDSILSVQLASRARAAGLPVSPRMIF MMAR_3691|M.marinum_M LEELLEITGID----RDENYFALGGDSIIAIKWSAQAGALGLPFPPAMVF MUL_3634|M.ulcerans_Agy99 LEELLEITGID----RDENYFALGGDSIIAIKWSAQAGALGLPFPPAMVF MAB_2122|M.abscessus_ATCC_1997 LEELLEISDVD----PEDNFFALGGDSVISIQWSTRAAERGLAMTPQMVF MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 EHPVLCELAAAVDAKPHVEAEPDDKH------------------------ Rv2380c|M.tuberculosis_H37Rv EHPVLCELAAAVDAKPHVEAEPDDKH------------------------ TH_3141|M.thermoresistible__bu EHPTLHELAAAVEAREAVEARETAEAGGAEAGGAESGGGADGAERGAAAG Mvan_3845|M.vanbaalenii_PYR-1 EHPRLAELAAALDSGAGAAAEQPDTH------------------------ MSMEG_4511|M.smegmatis_MC2_155 EHPVLSELAAAIDAAGEGSAAQDVHH------------------------ Mflv_2696|M.gilvum_PYR-GCK EHPVVHDLAVALDTAKTPEVADVRHD------------------------ MAV_2013|M.avium_104 ENPTVQQLAAALDALGDNDSDGRLDDQ----------------------- MMAR_3691|M.marinum_M EHMTIAELAAAVDAANGEPVVEAD-------------------------- MUL_3634|M.ulcerans_Agy99 EHMTIAELAAAVDAANGEPVVEAD-------------------------- MAB_2122|M.abscessus_ATCC_1997 ECATIAQLAGAVDAADR-VVTEGDSHL----------------------- MLBr_00134|M.leprae_Br4923 -------------------------------------------------- Mb2401c|M.bovis_AF2122/97 --------HAPMSTSGLSPDELSALTASWDQWP---- Rv2380c|M.tuberculosis_H37Rv --------HAPMSTSGLSPDELSALTASWDQWP---- TH_3141|M.thermoresistible__bu DSGNGAASHAPMSTSGLSAEQLSALTASWNPAGEDAP Mvan_3845|M.vanbaalenii_PYR-1 --------HAPMSVSGLSEDELAALTASWGTGE---- MSMEG_4511|M.smegmatis_MC2_155 ---------APMEASGLSSDELAALTAAWGQSQDGKR Mflv_2696|M.gilvum_PYR-GCK ----------PMSASGLTPEELAMVATSWAAEQDGSP MAV_2013|M.avium_104 ---PADTRFEPMSTSGLSASDLAAVTQLWSSSREGTA MMAR_3691|M.marinum_M --PPPAQEYTPMSASGLAPDALAKLSASWLQQGSAS- MUL_3634|M.ulcerans_Agy99 --PPPAQEYTPMSASGLAPDALAKLSASWLQQGSAS- MAB_2122|M.abscessus_ATCC_1997 --VTPPVQSAPMSASGLSADALAELTASWQAQS---- MLBr_00134|M.leprae_Br4923 -------------------------------------