For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2856 | - | - | 100% (403) | cytochrome P450 |
M. thermoresistible (build 8) | TH_2585 | - | e-149 | 66.16% (393) | PUTATIVE putative cytochrome P450 123 |
M. thermoresistible (build 8) | TH_2539 | - | e-130 | 59.39% (394) | PUTATIVE cytochrome P450 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0789c | cyp123 | 3e-72 | 39.25% (400) | cytochrome P450 123 |
M. gilvum PYR-GCK | Mflv_2477 | - | 1e-167 | 70.75% (400) | cytochrome P450 |
M. tuberculosis H37Rv | Rv0766c | cyp123 | 3e-72 | 39.25% (400) | cytochrome P450 123 |
M. leprae Br4923 | MLBr_02088 | - | 1e-41 | 31.87% (342) | putative cytochrome p450 |
M. abscessus ATCC 19977 | MAB_1216c | - | 1e-70 | 36.78% (397) | cytochrome P450 |
M. marinum M | MMAR_4733 | cyp190A3 | 1e-165 | 69.75% (400) | cytochrome P450 190A3 Cyp190A3 |
M. avium 104 | MAV_0916 | - | 1e-164 | 69.00% (400) | cytochrome P450 monooxygenase |
M. smegmatis MC2 155 | MSMEG_4818 | - | 1e-152 | 65.50% (400) | putative cytochrome P450 123 |
M. ulcerans Agy99 | MUL_0324 | cyp189A7 | 2e-72 | 40.00% (395) | cytochrome P450 189A7 Cyp189A7 |
M. vanbaalenii PYR-1 | Mvan_2001 | - | 1e-155 | 66.58% (395) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment Mb0789c|M.bovis_AF2122/97 --------------------------MTVRVGDPE-LVLDPYDYDFHEDP Rv0766c|M.tuberculosis_H37Rv --------------------------MTVRVGDPE-LVLDPYDYDFHEDP MAB_1216c|M.abscessus_ATCC_199 --------------------------MTVAETSAVPLVFDPYDYDFHEDP TH_2856|M.thermoresistible__bu --------------------------MTTTKL-----IFDPFSEDFFNGP MMAR_4733|M.marinum_M --------------------------MTTSKV-----VFDPFSEEFFNGP Mflv_2477|M.gilvum_PYR-GCK --------------------------MTATDL-----VFDPFSEEFFNGP Mvan_2001|M.vanbaalenii_PYR-1 --------------------------MAVVDVGRDPVVFDPFSEEFYRDP MAV_0916|M.avium_104 --------------------------MTKPKL-----VFDPYSEDYFNNP MSMEG_4818|M.smegmatis_MC2_155 --------------------------MTTPQM-----IFDPFSEQYFENP MUL_0324|M.ulcerans_Agy99 --------------------------MTVTAAS--DVYFDPYDVELNADP MLBr_02088|M.leprae_Br4923 MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP . : . .* Mb0789c|M.bovis_AF2122/97 YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP Rv0766c|M.tuberculosis_H37Rv YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP MAB_1216c|M.abscessus_ATCC_199 YPYYRRLRDEAPLYRNDDLKFWALSRHHDVLQGFRNSEALSNANGVSMDK TH_2856|M.thermoresistible__bu YETYRRMREEAPVYYSEEYDFYALSRHADVAAAFKDFETYSSARGVDLA- MMAR_4733|M.marinum_M WETYRRMQAEAPVYYSEQYDFYALTRHADVAAGLKNFERYSSAYGIDLS- Mflv_2477|M.gilvum_PYR-GCK WEIYRRMRSEAPVYYNAEYDFYALSRHEDVAAAYKDFETYSSAYGLDLA- Mvan_2001|M.vanbaalenii_PYR-1 QGCYPRLRAEAPVYYNATYDFYALSRHADVAAGLKDFATYSSAYGVDLG- MAV_0916|M.avium_104 YEIYRRMREEAPLYYDEKEDFYALTRHVDVAAAFKDYETYSSARGCDLA- MSMEG_4818|M.smegmatis_MC2_155 FDIYRQMRDDAPLYYDSEQDFYALSRHEDVAAALKDHEAFSSSRGCDLA- MUL_0324|M.ulcerans_Agy99 YPMFRRLREEAPLYYNAQHGFYALSRFADVDRAIVDYQTFSSARGAILE- MLBr_02088|M.leprae_Br4923 FPVYRALIDYGPMQLPG-MPLTVFSSFSDCDEALRHPLSASDRLKATLAQ : : .*: : ..: . * . . *. : Mb0789c|M.bovis_AF2122/97 ----SSRTSEAYRVMSMLAMDDPAHLRMRTLVSKGFTPRRIRELEPQVLE Rv0766c|M.tuberculosis_H37Rv ----SSRTSEAYRVMSMLAMDDPAHLRMRTLVSKGFTPRRIRELEPQVLE MAB_1216c|M.abscessus_ATCC_199 ----ASFGPHAKLVMSFLAMDDPEHLRLRALVSKGFTPRRIRELEGQVVA TH_2856|M.thermoresistible__bu ----MVRNPEPPPHRSIIMMDPPEHRHMRSLLNRVFTPRAIQSLRSMVEE MMAR_4733|M.marinum_M ----MVRSGQKPPQ-SIIFMDPPDHRHMRSLLNKVFTPRAIQAQRQTVID Mflv_2477|M.gilvum_PYR-GCK ----TVRSDEPIPAKMIIIMDPPEHRQMRSLVNKVFTPRAIEALRPMVTE Mvan_2001|M.vanbaalenii_PYR-1 ----MVRRGEKVPAKMIISIDPPEHRAMRSLVNKVFTPRAIEALRTMVTD MAV_0916|M.avium_104 ----MVRRGISPEQKSIIFMDPPEHRHMRSLLNKAFTPRAIQSQRETIIE MSMEG_4818|M.smegmatis_MC2_155 ----MVK-GDEPPQKSIIFMDPPEHRHMRSLLNKAFTPRAVQAQRDTVVE MUL_0324|M.ulcerans_Agy99 ----FIKANIDIPAGVLVFEDPPVHDVHRKLLSRMFTPRKINDLEPKIRE MLBr_02088|M.leprae_Br4923 QAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDIAA :: * * * * *:.: *:*: :. . : Mb0789c|M.bovis_AF2122/97 LARIHLDSALQTES---FDFVAEFAGKLPMDVISELIGVPDTDRARIRAL Rv0766c|M.tuberculosis_H37Rv LARIHLDSALQTES---FDFVAEFAGKLPMDVISELIGVPDTDRARIRAL MAB_1216c|M.abscessus_ATCC_199 LARTHLDRALANASDRSFDFIAEYAGKLPMDVISELMGVPESDRARIREL TH_2856|M.thermoresistible__bu VVDDCLA-AVDPAG---FDAVQDFSALFPIEIISRMLGVPTEYRQQMRLW MMAR_4733|M.marinum_M KIDKYLG-ALDPEG---FDAVQEFSGPFPVEVITTMLGVPERHAQQVRHW Mflv_2477|M.gilvum_PYR-GCK TIDRYLS-QVDRDS---FDVVQDFSALFPVQVITQMLGVPEEYRKQVGEW Mvan_2001|M.vanbaalenii_PYR-1 TVTRFLS-AVRGDS---FDVVQDFSVYFPVDVITQMLGVPEKYRQQVRLW MAV_0916|M.avium_104 VVDKYLS-AADPDN---FDVVQDFSGPFPVEVITRMAGVPEEYRQQVRHW MSMEG_4818|M.smegmatis_MC2_155 QVEHYLG-QIDSDE---FDVVQDFSGPFPVEVITRMAGVEPEYRQQVRHW MUL_0324|M.ulcerans_Agy99 FCARSLDPLIGSGR---FDFVADLGAQMPMRVIGMLLGVPEEDQEAARDF MLBr_02088|M.leprae_Br4923 LVDSLLDKGAAAGQ---FDVIADLAFPLAVAVICRLLGVPYEDAPEFGRV * ** : : . :.: :* : ** Mb0789c|M.bovis_AF2122/97 ADAVLH------REDGV-ADVPPPAMAASIELMRYYADLIAEFRRRPANN Rv0766c|M.tuberculosis_H37Rv ADAVLH------REDGV-ADVPPPAMAASIELMRYYADLIAEFRRRPANN MAB_1216c|M.abscessus_ATCC_199 ADGVMH------REDGL-ADVPPEAIQASFDLMTYYIEMVRERRRRPTED TH_2856|M.thermoresistible__bu VDDFLH------REPGE-VEMSRRGVQAATEMAVYLYKLTKQRRHDLGDD MMAR_4733|M.marinum_M IDESLT------REPGQ-VEVGEQGMQANINTAMLYYDLVKQRRDDPRDD Mflv_2477|M.gilvum_PYR-GCK VDTSLR------REPGQ-IDMSDEGMQAVGELMGLYYSIIQQRREDPRDD Mvan_2001|M.vanbaalenii_PYR-1 IDESLH------REPGQ-IDMSEAGMQAMAETWLMYYDLIKQRRADPRDD MAV_0916|M.avium_104 IDTSLH------HEPGQ-IEVSEAGMQANIDTAMYYFGLVQERRQNPQDD MSMEG_4818|M.smegmatis_MC2_155 IDTSLS------REPGQ-VAYSEAGMKANIDTAMYYYSLVQKRRENPQDD MUL_0324|M.ulcerans_Agy99 ATAQLR------TEAGKPMKASADGMVS----GDFFAHYIDWRAEHPSSD MLBr_02088|M.leprae_Br4923 SALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRGTPGED : * : : .: Mb0789c|M.bovis_AF2122/97 LTSALLAAELDGD-----RLSDQEIMAFLFLMVIAGNETTTKLLANAVYW Rv0766c|M.tuberculosis_H37Rv LTSALLAAELDGD-----RLSDQEIMAFLFLMVIAGNETTTKLLANAVYW MAB_1216c|M.abscessus_ATCC_199 LTSALLQAEIDGD-----RLTDEEVLAFLFLMVIAGNETTTKLLANAVYW TH_2856|M.thermoresistible__bu LLSRLITAEIERENGKRGPLDNVEITQFAMLLGGAGAETVTKLIGNAAVV MMAR_4733|M.marinum_M LFTKLINAEIEREDGQVTNLDDLEIAGFATLLGGAGAETVTKLVGNAAVV Mflv_2477|M.gilvum_PYR-GCK MFSRLIAAEITREDGEKESLDDFEIAGFATLLGGAGAETVTKLVGNAAVT Mvan_2001|M.vanbaalenii_PYR-1 MISALIAAEVEREDGTVDRLKDSEIAGFATLLGGAGAETVTKLVGSAVVT MAV_0916|M.avium_104 MISRLIAAEIPGENGQMRKLDDIEITGFATLLGGAGAETVTKLLGNAAVI MSMEG_4818|M.smegmatis_MC2_155 MISRLIAAEIPGENGEMRRLDDVEITGFATLLGGAGAETVTKLIGTAMVT MUL_0324|M.ulcerans_Agy99 IMTELLNAEFEDETGTVRRLRRDELLTYVSVVSGAGNETTTRLIGWAGKV MLBr_02088|M.leprae_Br4923 LISRLIELDESGD-----QLTEEEIIATCGLLLVAGHETTVNLIANAVLA : : *: : : * *: :: ** **...*:. * Mb0789c|M.bovis_AF2122/97 AAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAHDLTLYDTTI Rv0766c|M.tuberculosis_H37Rv AAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAHDLTLYDTTI MAB_1216c|M.abscessus_ATCC_199 GHRNPDQLATVHADHDRIPLWVEESLRYDTSSQILARTVAEDITVYDTKI TH_2856|M.thermoresistible__bu FAQHPDQWRLLLEDRSKIPAAVEELLRYEAPAQYNVRCSRREVTLHGVTI MMAR_4733|M.marinum_M FARNPEQWQKLLDDRSKVPAAVEELLRYEAPSQYQVRRAMEDVELHGVTI Mflv_2477|M.gilvum_PYR-GCK FARHPDQWQKLLDDRSKIPAAVEELLRFEAPNQYNVRRSMKDVELHGVTI Mvan_2001|M.vanbaalenii_PYR-1 FARHPEQWQQLLDDRGKIGVAIEELLRYDAPVQYNVRRSNHPVTLHGVTI MAV_0916|M.avium_104 FARHPDQWQKLQDDRDKIPGAVEELLRYEGPVQYNVRYTLKEAHVSGGVI MSMEG_4818|M.smegmatis_MC2_155 FAKFPDQWQKLLDDRSKVPAAVEELLRYEGPVQYNVRYTLKEARVPSGTI MUL_0324|M.ulcerans_Agy99 LAEHPDQRRALVEDPSLIPQAVEELLRYEAPAPHVARYVTRDLRYYGQSV MLBr_02088|M.leprae_Br4923 MLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTTL . * * : : :** **:: . * . : Mb0789c|M.bovis_AF2122/97 PEGEVLLLLPGSANRDDRVFD-DPDDYRIGREIG-CKLVSFGSGAHFCLG Rv0766c|M.tuberculosis_H37Rv PEGEVLLLLPGSANRDDRVFD-DPDDYRIGREIG-CKLVSFGSGAHFCLG MAB_1216c|M.abscessus_ATCC_199 PAGDILLLLPGSANRDDRVFD-DADQYRIGREIG-AKLVSFGSGAHFCLG TH_2856|M.thermoresistible__bu PAGKPVFLIGGSANRDPRAWT-DPDTFDIERDRTEAQNLGFGYGIHSCLG MMAR_4733|M.marinum_M PAGKPVFLINGAANRDPHAWT-DPDKFDIDRDPHEATNLGFGYGIHSCLG Mflv_2477|M.gilvum_PYR-GCK PEGKPVFLLAGSANRDPDAFT-DADTFDIDRDRSEAQNLGFGYGVHSCLG Mvan_2001|M.vanbaalenii_PYR-1 PAGAPVFLLGASANRDPDAWT-APDVFDINRDRTEAQNLGFGYGIHSCLG MAV_0916|M.avium_104 PAGKPVFLCGAAANRDPEAFT-DADTFDIERDQTEAQHLGLGYGIHSCLG MSMEG_4818|M.smegmatis_MC2_155 PAGKPVFLLKASANRDERAWT-DPDVFDIDRDRTEAQNLGLGYGIHSCLG MUL_0324|M.ulcerans_Agy99 PEGSIMMMLIGAANRDHRQFRPDGDVFNIRREP--HQHLTFSVGTHYCLG MLBr_02088|M.leprae_Br4923 TEGDTMVLLLAAANRDPAVYS-RPDEFDPDRPSS--RHLAFAVGSHFCLG . * :.: .:**** : * : * : :. * * *** Mb0789c|M.bovis_AF2122/97 AHLARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR Rv0766c|M.tuberculosis_H37Rv AHLARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR MAB_1216c|M.abscessus_ATCC_199 AHLARMEAKVALTELFTRISGYEIDERNSVRVHSSNVRGFAHLPMTVQLR TH_2856|M.thermoresistible__bu AALARMESAIALERMLDFMPRYEVDWDNCRRVNMQNVAGWQNVPVRMLGR MMAR_4733|M.marinum_M AALARMESAIALEKLLDFMPAFEVDWAGCKRVHMQNVAGWQSVPVRVLR- Mflv_2477|M.gilvum_PYR-GCK AALARMESAIALDRLLDFMPRYEVLFDECRRVSAQNVAGWSHVPVRVLR- Mvan_2001|M.vanbaalenii_PYR-1 AALARLESSIALDMLLDFMPRYGVEWDGCRRVSMQNVSGWANVPVRIL-- MAV_0916|M.avium_104 AALARLESRIALERLLDFMPRYEVDWAGCRRVTMQNVAGWKNVPVKVLR- MSMEG_4818|M.smegmatis_MC2_155 AALARLESTIALERLLDFMPRYEVKWDGLQRVHMQNVAGYSHVPVKVLR- MUL_0324|M.ulcerans_Agy99 SALARLEGRIALEDILKRFPEWDVDLGNAKLSPTSTVRGWESMPAVFD-- MLBr_02088|M.leprae_Br4923 AALARLEATVTLSAISARFPQVQLAG-ELVYKPNVAMRGMSALPVQV--- : ***:*. ::* : : : : * :* . Mb0789c|M.bovis_AF2122/97 --- Rv0766c|M.tuberculosis_H37Rv --- MAB_1216c|M.abscessus_ATCC_199 EGR TH_2856|M.thermoresistible__bu --- MMAR_4733|M.marinum_M --- Mflv_2477|M.gilvum_PYR-GCK --- Mvan_2001|M.vanbaalenii_PYR-1 --- MAV_0916|M.avium_104 --- MSMEG_4818|M.smegmatis_MC2_155 --- MUL_0324|M.ulcerans_Agy99 --- MLBr_02088|M.leprae_Br4923 ---