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M. thermoresistible (build 8) TH_2856 (-)

annotation: cytochrome P450
coordinates: 3160231 - 3161439
length: 403

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2856--100% (403)cytochrome P450
M. thermoresistible (build 8)TH_2585-e-14966.16% (393) PUTATIVE putative cytochrome P450 123
M. thermoresistible (build 8)TH_2539-e-13059.39% (394) PUTATIVE cytochrome P450

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0789ccyp1233e-7239.25% (400) cytochrome P450 123
M. gilvum PYR-GCKMflv_2477-1e-16770.75% (400) cytochrome P450
M. tuberculosis H37RvRv0766ccyp1233e-7239.25% (400) cytochrome P450 123
M. leprae Br4923MLBr_02088-1e-4131.87% (342) putative cytochrome p450
M. abscessus ATCC 19977MAB_1216c-1e-7036.78% (397) cytochrome P450
M. marinum MMMAR_4733cyp190A31e-16569.75% (400) cytochrome P450 190A3 Cyp190A3
M. avium 104MAV_0916-1e-16469.00% (400) cytochrome P450 monooxygenase
M. smegmatis MC2 155MSMEG_4818-1e-15265.50% (400) putative cytochrome P450 123
M. ulcerans Agy99MUL_0324cyp189A72e-7240.00% (395) cytochrome P450 189A7 Cyp189A7
M. vanbaalenii PYR-1Mvan_2001-1e-15566.58% (395) cytochrome P450

CLUSTAL 2.0.9 multiple sequence alignment


Mb0789c|M.bovis_AF2122/97           --------------------------MTVRVGDPE-LVLDPYDYDFHEDP
Rv0766c|M.tuberculosis_H37Rv        --------------------------MTVRVGDPE-LVLDPYDYDFHEDP
MAB_1216c|M.abscessus_ATCC_199      --------------------------MTVAETSAVPLVFDPYDYDFHEDP
TH_2856|M.thermoresistible__bu      --------------------------MTTTKL-----IFDPFSEDFFNGP
MMAR_4733|M.marinum_M               --------------------------MTTSKV-----VFDPFSEEFFNGP
Mflv_2477|M.gilvum_PYR-GCK          --------------------------MTATDL-----VFDPFSEEFFNGP
Mvan_2001|M.vanbaalenii_PYR-1       --------------------------MAVVDVGRDPVVFDPFSEEFYRDP
MAV_0916|M.avium_104                --------------------------MTKPKL-----VFDPYSEDYFNNP
MSMEG_4818|M.smegmatis_MC2_155      --------------------------MTTPQM-----IFDPFSEQYFENP
MUL_0324|M.ulcerans_Agy99           --------------------------MTVTAAS--DVYFDPYDVELNADP
MLBr_02088|M.leprae_Br4923          MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP
                                                               .          :   .     .*

Mb0789c|M.bovis_AF2122/97           YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP
Rv0766c|M.tuberculosis_H37Rv        YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP
MAB_1216c|M.abscessus_ATCC_199      YPYYRRLRDEAPLYRNDDLKFWALSRHHDVLQGFRNSEALSNANGVSMDK
TH_2856|M.thermoresistible__bu      YETYRRMREEAPVYYSEEYDFYALSRHADVAAAFKDFETYSSARGVDLA-
MMAR_4733|M.marinum_M               WETYRRMQAEAPVYYSEQYDFYALTRHADVAAGLKNFERYSSAYGIDLS-
Mflv_2477|M.gilvum_PYR-GCK          WEIYRRMRSEAPVYYNAEYDFYALSRHEDVAAAYKDFETYSSAYGLDLA-
Mvan_2001|M.vanbaalenii_PYR-1       QGCYPRLRAEAPVYYNATYDFYALSRHADVAAGLKDFATYSSAYGVDLG-
MAV_0916|M.avium_104                YEIYRRMREEAPLYYDEKEDFYALTRHVDVAAAFKDYETYSSARGCDLA-
MSMEG_4818|M.smegmatis_MC2_155      FDIYRQMRDDAPLYYDSEQDFYALSRHEDVAAALKDHEAFSSSRGCDLA-
MUL_0324|M.ulcerans_Agy99           YPMFRRLREEAPLYYNAQHGFYALSRFADVDRAIVDYQTFSSARGAILE-
MLBr_02088|M.leprae_Br4923          FPVYRALIDYGPMQLPG-MPLTVFSSFSDCDEALRHPLSASDRLKATLAQ
                                       :  :   .*:       : ..: . *   .  .    *.     :  

Mb0789c|M.bovis_AF2122/97           ----SSRTSEAYRVMSMLAMDDPAHLRMRTLVSKGFTPRRIRELEPQVLE
Rv0766c|M.tuberculosis_H37Rv        ----SSRTSEAYRVMSMLAMDDPAHLRMRTLVSKGFTPRRIRELEPQVLE
MAB_1216c|M.abscessus_ATCC_199      ----ASFGPHAKLVMSFLAMDDPEHLRLRALVSKGFTPRRIRELEGQVVA
TH_2856|M.thermoresistible__bu      ----MVRNPEPPPHRSIIMMDPPEHRHMRSLLNRVFTPRAIQSLRSMVEE
MMAR_4733|M.marinum_M               ----MVRSGQKPPQ-SIIFMDPPDHRHMRSLLNKVFTPRAIQAQRQTVID
Mflv_2477|M.gilvum_PYR-GCK          ----TVRSDEPIPAKMIIIMDPPEHRQMRSLVNKVFTPRAIEALRPMVTE
Mvan_2001|M.vanbaalenii_PYR-1       ----MVRRGEKVPAKMIISIDPPEHRAMRSLVNKVFTPRAIEALRTMVTD
MAV_0916|M.avium_104                ----MVRRGISPEQKSIIFMDPPEHRHMRSLLNKAFTPRAIQSQRETIIE
MSMEG_4818|M.smegmatis_MC2_155      ----MVK-GDEPPQKSIIFMDPPEHRHMRSLLNKAFTPRAVQAQRDTVVE
MUL_0324|M.ulcerans_Agy99           ----FIKANIDIPAGVLVFEDPPVHDVHRKLLSRMFTPRKINDLEPKIRE
MLBr_02088|M.leprae_Br4923          QAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQALEGDIAA
                                                    ::  * * *   * *:.: *:*: :.  .  :  

Mb0789c|M.bovis_AF2122/97           LARIHLDSALQTES---FDFVAEFAGKLPMDVISELIGVPDTDRARIRAL
Rv0766c|M.tuberculosis_H37Rv        LARIHLDSALQTES---FDFVAEFAGKLPMDVISELIGVPDTDRARIRAL
MAB_1216c|M.abscessus_ATCC_199      LARTHLDRALANASDRSFDFIAEYAGKLPMDVISELMGVPESDRARIREL
TH_2856|M.thermoresistible__bu      VVDDCLA-AVDPAG---FDAVQDFSALFPIEIISRMLGVPTEYRQQMRLW
MMAR_4733|M.marinum_M               KIDKYLG-ALDPEG---FDAVQEFSGPFPVEVITTMLGVPERHAQQVRHW
Mflv_2477|M.gilvum_PYR-GCK          TIDRYLS-QVDRDS---FDVVQDFSALFPVQVITQMLGVPEEYRKQVGEW
Mvan_2001|M.vanbaalenii_PYR-1       TVTRFLS-AVRGDS---FDVVQDFSVYFPVDVITQMLGVPEKYRQQVRLW
MAV_0916|M.avium_104                VVDKYLS-AADPDN---FDVVQDFSGPFPVEVITRMAGVPEEYRQQVRHW
MSMEG_4818|M.smegmatis_MC2_155      QVEHYLG-QIDSDE---FDVVQDFSGPFPVEVITRMAGVEPEYRQQVRHW
MUL_0324|M.ulcerans_Agy99           FCARSLDPLIGSGR---FDFVADLGAQMPMRVIGMLLGVPEEDQEAARDF
MLBr_02088|M.leprae_Br4923          LVDSLLDKGAAAGQ---FDVIADLAFPLAVAVICRLLGVPYEDAPEFGRV
                                         *           ** : : .  :.: :*  : **           

Mb0789c|M.bovis_AF2122/97           ADAVLH------REDGV-ADVPPPAMAASIELMRYYADLIAEFRRRPANN
Rv0766c|M.tuberculosis_H37Rv        ADAVLH------REDGV-ADVPPPAMAASIELMRYYADLIAEFRRRPANN
MAB_1216c|M.abscessus_ATCC_199      ADGVMH------REDGL-ADVPPEAIQASFDLMTYYIEMVRERRRRPTED
TH_2856|M.thermoresistible__bu      VDDFLH------REPGE-VEMSRRGVQAATEMAVYLYKLTKQRRHDLGDD
MMAR_4733|M.marinum_M               IDESLT------REPGQ-VEVGEQGMQANINTAMLYYDLVKQRRDDPRDD
Mflv_2477|M.gilvum_PYR-GCK          VDTSLR------REPGQ-IDMSDEGMQAVGELMGLYYSIIQQRREDPRDD
Mvan_2001|M.vanbaalenii_PYR-1       IDESLH------REPGQ-IDMSEAGMQAMAETWLMYYDLIKQRRADPRDD
MAV_0916|M.avium_104                IDTSLH------HEPGQ-IEVSEAGMQANIDTAMYYFGLVQERRQNPQDD
MSMEG_4818|M.smegmatis_MC2_155      IDTSLS------REPGQ-VAYSEAGMKANIDTAMYYYSLVQKRRENPQDD
MUL_0324|M.ulcerans_Agy99           ATAQLR------TEAGKPMKASADGMVS----GDFFAHYIDWRAEHPSSD
MLBr_02088|M.leprae_Br4923          SALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRGTPGED
                                        :          *         : :                    .:

Mb0789c|M.bovis_AF2122/97           LTSALLAAELDGD-----RLSDQEIMAFLFLMVIAGNETTTKLLANAVYW
Rv0766c|M.tuberculosis_H37Rv        LTSALLAAELDGD-----RLSDQEIMAFLFLMVIAGNETTTKLLANAVYW
MAB_1216c|M.abscessus_ATCC_199      LTSALLQAEIDGD-----RLTDEEVLAFLFLMVIAGNETTTKLLANAVYW
TH_2856|M.thermoresistible__bu      LLSRLITAEIERENGKRGPLDNVEITQFAMLLGGAGAETVTKLIGNAAVV
MMAR_4733|M.marinum_M               LFTKLINAEIEREDGQVTNLDDLEIAGFATLLGGAGAETVTKLVGNAAVV
Mflv_2477|M.gilvum_PYR-GCK          MFSRLIAAEITREDGEKESLDDFEIAGFATLLGGAGAETVTKLVGNAAVT
Mvan_2001|M.vanbaalenii_PYR-1       MISALIAAEVEREDGTVDRLKDSEIAGFATLLGGAGAETVTKLVGSAVVT
MAV_0916|M.avium_104                MISRLIAAEIPGENGQMRKLDDIEITGFATLLGGAGAETVTKLLGNAAVI
MSMEG_4818|M.smegmatis_MC2_155      MISRLIAAEIPGENGEMRRLDDVEITGFATLLGGAGAETVTKLIGTAMVT
MUL_0324|M.ulcerans_Agy99           IMTELLNAEFEDETGTVRRLRRDELLTYVSVVSGAGNETTTRLIGWAGKV
MLBr_02088|M.leprae_Br4923          LISRLIELDESGD-----QLTEEEIIATCGLLLVAGHETTVNLIANAVLA
                                    : : *:  :   :      *   *:     ::  ** **...*:. *   

Mb0789c|M.bovis_AF2122/97           AAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAHDLTLYDTTI
Rv0766c|M.tuberculosis_H37Rv        AAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAHDLTLYDTTI
MAB_1216c|M.abscessus_ATCC_199      GHRNPDQLATVHADHDRIPLWVEESLRYDTSSQILARTVAEDITVYDTKI
TH_2856|M.thermoresistible__bu      FAQHPDQWRLLLEDRSKIPAAVEELLRYEAPAQYNVRCSRREVTLHGVTI
MMAR_4733|M.marinum_M               FARNPEQWQKLLDDRSKVPAAVEELLRYEAPSQYQVRRAMEDVELHGVTI
Mflv_2477|M.gilvum_PYR-GCK          FARHPDQWQKLLDDRSKIPAAVEELLRFEAPNQYNVRRSMKDVELHGVTI
Mvan_2001|M.vanbaalenii_PYR-1       FARHPEQWQQLLDDRGKIGVAIEELLRYDAPVQYNVRRSNHPVTLHGVTI
MAV_0916|M.avium_104                FARHPDQWQKLQDDRDKIPGAVEELLRYEGPVQYNVRYTLKEAHVSGGVI
MSMEG_4818|M.smegmatis_MC2_155      FAKFPDQWQKLLDDRSKVPAAVEELLRYEGPVQYNVRYTLKEARVPSGTI
MUL_0324|M.ulcerans_Agy99           LAEHPDQRRALVEDPSLIPQAVEELLRYEAPAPHVARYVTRDLRYYGQSV
MLBr_02088|M.leprae_Br4923          MLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTTL
                                      . * *   :  :       :** **:: .     *   .        :

Mb0789c|M.bovis_AF2122/97           PEGEVLLLLPGSANRDDRVFD-DPDDYRIGREIG-CKLVSFGSGAHFCLG
Rv0766c|M.tuberculosis_H37Rv        PEGEVLLLLPGSANRDDRVFD-DPDDYRIGREIG-CKLVSFGSGAHFCLG
MAB_1216c|M.abscessus_ATCC_199      PAGDILLLLPGSANRDDRVFD-DADQYRIGREIG-AKLVSFGSGAHFCLG
TH_2856|M.thermoresistible__bu      PAGKPVFLIGGSANRDPRAWT-DPDTFDIERDRTEAQNLGFGYGIHSCLG
MMAR_4733|M.marinum_M               PAGKPVFLINGAANRDPHAWT-DPDKFDIDRDPHEATNLGFGYGIHSCLG
Mflv_2477|M.gilvum_PYR-GCK          PEGKPVFLLAGSANRDPDAFT-DADTFDIDRDRSEAQNLGFGYGVHSCLG
Mvan_2001|M.vanbaalenii_PYR-1       PAGAPVFLLGASANRDPDAWT-APDVFDINRDRTEAQNLGFGYGIHSCLG
MAV_0916|M.avium_104                PAGKPVFLCGAAANRDPEAFT-DADTFDIERDQTEAQHLGLGYGIHSCLG
MSMEG_4818|M.smegmatis_MC2_155      PAGKPVFLLKASANRDERAWT-DPDVFDIDRDRTEAQNLGLGYGIHSCLG
MUL_0324|M.ulcerans_Agy99           PEGSIMMMLIGAANRDHRQFRPDGDVFNIRREP--HQHLTFSVGTHYCLG
MLBr_02088|M.leprae_Br4923          TEGDTMVLLLAAANRDPAVYS-RPDEFDPDRPSS--RHLAFAVGSHFCLG
                                    . *  :.:  .:****   :    * :   *       : :. * * ***

Mb0789c|M.bovis_AF2122/97           AHLARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR
Rv0766c|M.tuberculosis_H37Rv        AHLARMEARVALGALLRRIRNYEVDDDNVVRVHSSNVRGFAHLPISVQAR
MAB_1216c|M.abscessus_ATCC_199      AHLARMEAKVALTELFTRISGYEIDERNSVRVHSSNVRGFAHLPMTVQLR
TH_2856|M.thermoresistible__bu      AALARMESAIALERMLDFMPRYEVDWDNCRRVNMQNVAGWQNVPVRMLGR
MMAR_4733|M.marinum_M               AALARMESAIALEKLLDFMPAFEVDWAGCKRVHMQNVAGWQSVPVRVLR-
Mflv_2477|M.gilvum_PYR-GCK          AALARMESAIALDRLLDFMPRYEVLFDECRRVSAQNVAGWSHVPVRVLR-
Mvan_2001|M.vanbaalenii_PYR-1       AALARLESSIALDMLLDFMPRYGVEWDGCRRVSMQNVSGWANVPVRIL--
MAV_0916|M.avium_104                AALARLESRIALERLLDFMPRYEVDWAGCRRVTMQNVAGWKNVPVKVLR-
MSMEG_4818|M.smegmatis_MC2_155      AALARLESTIALERLLDFMPRYEVKWDGLQRVHMQNVAGYSHVPVKVLR-
MUL_0324|M.ulcerans_Agy99           SALARLEGRIALEDILKRFPEWDVDLGNAKLSPTSTVRGWESMPAVFD--
MLBr_02088|M.leprae_Br4923          AALARLEATVTLSAISARFPQVQLAG-ELVYKPNVAMRGMSALPVQV---
                                    : ***:*. ::*  :   :    :            : *   :*  .   

Mb0789c|M.bovis_AF2122/97           ---
Rv0766c|M.tuberculosis_H37Rv        ---
MAB_1216c|M.abscessus_ATCC_199      EGR
TH_2856|M.thermoresistible__bu      ---
MMAR_4733|M.marinum_M               ---
Mflv_2477|M.gilvum_PYR-GCK          ---
Mvan_2001|M.vanbaalenii_PYR-1       ---
MAV_0916|M.avium_104                ---
MSMEG_4818|M.smegmatis_MC2_155      ---
MUL_0324|M.ulcerans_Agy99           ---
MLBr_02088|M.leprae_Br4923          ---