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MTSPPLDPDAAARIASFGETAPMRQRGLPAVRAGLESAPRPATMPEMASVTEALVPSAAGGIPVRIYRPT TDSGVAVLVYLHGGGLVMGSNRSFEPLARELASASAATVVAVDYRLAPESPPPAQFDDAYAATEWVSRKA GELGVDADRLAVIGDSAGGSLAAAVALAARDRRGPPICAQVLLYPGLDRDMSVASIAAMPDAPLLIRDDI DYMHALVDGDAGPPTDPYLVPAYAADLSGLPPAIVVTAGCDPIRDWGERYADRLRDAGVQTTVTRYPGMY HGFLMRSDATARGRLAIAEIGGLLRAKFTHPLRFDVPITGRHSTPTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3032 | - | - | 100% (327) | alpha/beta hydrolase domain-containing protein |
| M. avium 104 | MAV_3377 | - | 8e-48 | 43.18% (264) | alpha/beta hydrolase domain-containing protein |
| M. avium 104 | MAV_3025 | - | 3e-45 | 39.67% (305) | esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1435c | lipI | 3e-48 | 40.77% (287) | lipase LipH |
| M. gilvum PYR-GCK | Mflv_4562 | - | 1e-125 | 71.02% (314) | alpha/beta hydrolase domain-containing protein |
| M. tuberculosis H37Rv | Rv1400c | lipI | 3e-48 | 40.77% (287) | lipase LipH |
| M. leprae Br4923 | MLBr_00314 | - | 3e-15 | 26.73% (318) | putative esterase |
| M. abscessus ATCC 19977 | MAB_2814 | - | 4e-48 | 42.69% (260) | lipase LipH |
| M. marinum M | MMAR_1746 | lipN | 4e-46 | 39.44% (284) | lipase/esterase LipN |
| M. smegmatis MC2 155 | MSMEG_2875 | - | 1e-123 | 71.88% (313) | esterase |
| M. thermoresistible (build 8) | TH_2802 | - | 1e-125 | 70.93% (313) | PUTATIVE esterase |
| M. ulcerans Agy99 | MUL_1989 | lipN | 4e-46 | 39.44% (284) | lipase/esterase LipN |
| M. vanbaalenii PYR-1 | Mvan_2872 | - | 1e-115 | 65.52% (319) | alpha/beta hydrolase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1435c|M.bovis_AF2122/97 ----------------------MPSLDNTADEK-----------------
Rv1400c|M.tuberculosis_H37Rv ----------------------MPSLDNTADEK-----------------
MAB_2814|M.abscessus_ATCC_1997 -------------------------MTATAG-------------------
MMAR_1746|M.marinum_M MTNSLPGETDLHPETVHATMSWLSRVQNTVTVVGAKVIPWVPDVAKRLIT
MUL_1989|M.ulcerans_Agy99 MTNSLPGETDLHPETVHATMSWLSRVQNTVTVVGAKVIPWVPDVAKRLIT
TH_2802|M.thermoresistible__bu -----------------MNHP-VPPLDPDAAAR-----------------
Mvan_2872|M.vanbaalenii_PYR-1 -----------------MNDPHRPALDPDAAAR-----------------
MSMEG_2875|M.smegmatis_MC2_155 ------------MTTSPPSPPQGPPLDPDAAAR-----------------
Mflv_4562|M.gilvum_PYR-GCK -------------------MP-GPTLDPDAAAR-----------------
MAV_3032|M.avium_104 --------------------MTSPPLDPDAAAR-----------------
MLBr_00314|M.leprae_Br4923 ------------MAISAGAPVEIVESGPSIAAR-----------------
Mb1435c|M.bovis_AF2122/97 ---------PAIDPILLKVLDAVPFR----LSIDDGIEAVRQRLRDLP--
Rv1400c|M.tuberculosis_H37Rv ---------PAIDPILLKVLDAVPFR----LSIDDGIEAVRQRLRDLP--
MAB_2814|M.abscessus_ATCC_1997 -----------IDPIIVKILEAVPIQ----LVSPDGPQASRDAYRAIATA
MMAR_1746|M.marinum_M RGRSVIIDGNTLDPALQLMLSGMRVVGLDGLVIDDDLAASRAHMREAMLG
MUL_1989|M.ulcerans_Agy99 RGRSVIIDGNTLDPALQLMLSGMRVVGLDGLVIDDDLAASRAHMREAMLG
TH_2802|M.thermoresistible__bu ---------------IASLGPPAPMR-------RRGLQAVRDAIESAP-L
Mvan_2872|M.vanbaalenii_PYR-1 ---------------VAAFGPPVPIR-------DRGLQAVRDAIESAP-P
MSMEG_2875|M.smegmatis_MC2_155 ---------------IAGFGKPAPVR-------DRGLETVRAAIESAP-L
Mflv_4562|M.gilvum_PYR-GCK ---------------VASFGPIPPMH-------ERGLDAVRAGVENTP-V
MAV_3032|M.avium_104 ---------------IASFGETAPMR-------QRGLPAVRAGLESAP-R
MLBr_00314|M.leprae_Br4923 ---------------LASLTSRLTIR---------PILAVGSYVPQLPWP
: . . :
Mb1435c|M.bovis_AF2122/97 RQPVHPELRVVDLAIDGPAGPIGTR------IYWPPTCPDQAEAPVVLYF
Rv1400c|M.tuberculosis_H37Rv RQPVHPELRVVDLAIDGPAGPIGTR------IYWPPTCPDQAEAPVVLYF
MAB_2814|M.abscessus_ATCC_1997 RPPWIEVANIEDRTIPGPAGEIPVR------IYSP---AEGGVRPVFVLI
MMAR_1746|M.marinum_M FPGPQIHVDVEELTLPGPAGDISAR------HYRP---PGDAAAPLLVFY
MUL_1989|M.ulcerans_Agy99 FPGPQIHVDVEELTLPGPAGDISAR------HYRP---PGDAAAPLLVFY
TH_2802|M.thermoresistible__bu PTDMPAMASIVDRAVPGPGGDIPVR------IHRPERGCGDPAP-AVLYF
Mvan_2872|M.vanbaalenii_PYR-1 PTDMPTMADIGDAEVAGPGGRVPVR------IYRPAN-DGGPCP-VIVHL
MSMEG_2875|M.smegmatis_MC2_155 PSDMPPMAEIVDRTVPASDREIGVR------VYRPEQVGHDGAP-VILHF
Mflv_4562|M.gilvum_PYR-GCK PDDMPAMASIEERCAPGPDGPIPLR------IYRPTD--ATDAS-VVVYF
MAV_3032|M.avium_104 PATMPEMASVTEALVPSAAGGIPVR------IYRPTT--DSGVA-VLVYL
MLBr_00314|M.leprae_Br4923 FGLIDHAARVLLPVTNAARAEVNLSNTSAQLVRAAGVRPADGSGRIVLYL
: .. : . .:
Mb1435c|M.bovis_AF2122/97 HGGGFVMGDLDTHDGTCRQHAVGADAIVVSVDYRLAPEHPYPAAIEDAWA
Rv1400c|M.tuberculosis_H37Rv HGGGFVMGDLDTHDGTCRQHAVGADAIVVSVDYRLAPEHPYPAAIEDAWA
MAB_2814|M.abscessus_ATCC_1997 HGGGWVIGDLDTHDAVARAAAVQADAVVVSVDYRLAPEHPYPAAVEDCWA
MMAR_1746|M.marinum_M HGGGWALGDLDTHDAVCRLTCRDAGIHVLAIDYRLSPEDRAPAAIDDAFA
MUL_1989|M.ulcerans_Agy99 HGGGWALGDLDTHDAVCRLTCRDAGIHVLAIDYRLSPEHRAPAAIDDAFA
TH_2802|M.thermoresistible__bu HGGGLVMGSNHSFEPLARGLAAASGAVVVAVDYRLAPEHPPPAQFDDAWA
Mvan_2872|M.vanbaalenii_PYR-1 HGGGLVMGSNRSFEPMARAMAAASGAAVVAVDYRLAPENPPPAQFEDAWT
MSMEG_2875|M.smegmatis_MC2_155 HGGGLVMGSVHSFEPLARGLAAAAGAVVVAVDYRLAPEYPPPAQFDDAYA
Mflv_4562|M.gilvum_PYR-GCK HGGGMVMGSNRSFEPLARALAAGSTATVVSVDYRLAPEHPAPAQFVDCSA
MAV_3032|M.avium_104 HGGGLVMGSNRSFEPLARELASASAATVVAVDYRLAPESPPPAQFDDAYA
MLBr_00314|M.leprae_Br4923 HGGAFLGCGANSHRRLVETLSKLADSPILVVNYRLLPKHSIGMALDDCHD
***. . :. . . : :: ::*** *: . *.
Mb1435c|M.bovis_AF2122/97 ATRWVAEHGRQVGADLGRIAVAGDSAGGTIAAVIAQRARDMGG---PPIV
Rv1400c|M.tuberculosis_H37Rv ATRWVAEHGRQVGADLGRIAVAGDSAGGTIAAVIAQRARDMGG---PPIV
MAB_2814|M.abscessus_ATCC_1997 ALQWVHEHAAEIGGDPGRLAVGGDSAGGNLSAVMAQLARDNG----IDLA
MMAR_1746|M.marinum_M AFEWAHAHAAELGALPGRVAVGGDSAGGNLAAVVSQLARDSGG---PAPI
MUL_1989|M.ulcerans_Agy99 AFEWAHAHAAELGALPGRVAVGGDSAGGNLAAVVSQLARDSGG---PAPI
TH_2802|M.thermoresistible__bu TTRWVAAHADELGLDTSRLAVAGDSAGGALAAAVALAARDRGG---PELL
Mvan_2872|M.vanbaalenii_PYR-1 VTKWVAADAERLRFDPGKIVVSGDSAGGGLAAAVTLAARDEGG---PRLF
MSMEG_2875|M.smegmatis_MC2_155 ATEWVARHAEELGVDARRLVVAGDSAGGGLAAAVALAARDHGG---PAIF
Mflv_4562|M.gilvum_PYR-GCK VTTWVAENATSLGVDPARLAVAGDSAGGSLAAAVTLAARDCGG---PVIC
MAV_3032|M.avium_104 ATEWVSRKAGELGVDADRLAVIGDSAGGSLAAAVALAARDRRG---PPIC
MLBr_00314|M.leprae_Br4923 GYQWLRR----LGYDPEQIVLAGDSAGGYLALALAQRLQDVGEEPAALVA
* : ::.: ****** :: .:: :*
Mb1435c|M.bovis_AF2122/97 FQLLWYPSTLWDQSLPSLAENADAPILDVKAIAAFSRWYAGEIDLHNPPA
Rv1400c|M.tuberculosis_H37Rv FQLLWYPSTLWDQSLPSLAENADAPILDVKAIAAFSRWYAGEIDLHNPPA
MAB_2814|M.abscessus_ATCC_1997 FQVLWYPATTFDTTLPSMVENAEAPVLDFKTVGALSKWYLGDTNPATAGP
MMAR_1746|M.marinum_M FQWLIYPRTDFAGRTRSASLFARGFLLTKRDIDWFHSQYLKGSGIEPTDP
MUL_1989|M.ulcerans_Agy99 FQWLIYPRTDFAGRTRSASLFARGFLLTKRDIDWFHSQYLKGSGIEPTDP
TH_2802|M.thermoresistible__bu AQLLMYPGLDRDLAAPSIVAMPEAPMLSRDDIVYLHELADLGAGTP-HDP
Mvan_2872|M.vanbaalenii_PYR-1 AQVLMYPGLDRDMAAPSILANPHAPMLTHDDIVYLHELADIGAGTS-HDT
MSMEG_2875|M.smegmatis_MC2_155 AQVLLYPGLDRDMGAQSIVEMPDAPMLSRDDILYMHDLADIGAGSP-HDP
Mflv_4562|M.gilvum_PYR-GCK AQVLMYPGLDRDMAAPSMVAMPDAPLLSRADIDYMHELADDGVGAP-HDA
MAV_3032|M.avium_104 AQVLLYPGLDRDMSVASIAAMPDAPLLIRDDIDYMHALVDGDAGPP-TDP
MLBr_00314|M.leprae_Br4923 ISPLLQLAKKGKQAHPNAKTDAMFPPKAFDALGRLVASSAAKNKVDDKPE
. * . . : :
Mb1435c|M.bovis_AF2122/97 PMAPGRAENLADLPPAYIAVAGYDPLRDDGIRYGELLAAAGVPVEVHNAQ
Rv1400c|M.tuberculosis_H37Rv PMAPGRAENLADLPPAYIAVAGYDPLRDDGIRYGELLAAAGVPVEVHNAQ
MAB_2814|M.abscessus_ATCC_1997 TLVPARAENFEGLAPAFIGTAQFDPLRDDGAKYAELLRDAGVPVQLHNAP
MMAR_1746|M.marinum_M RVSPLRAESLAGLAPALIAVAGFDPLRDEGENYATALRAAGTPVDLRAMG
MUL_1989|M.ulcerans_Agy99 RVSPLRAESLAGLAPALIAVAGFDPLRDEGENYATALRAAGTPVDLRAMG
TH_2802|M.thermoresistible__bu YRVPAYATDLGGLPQTIIVTGACDPIRDWGERYAGRLRDAGVQTTVTRYP
Mvan_2872|M.vanbaalenii_PYR-1 RRVPAYATDLTGLPQAIMVTGELDPISDWGERYAARLRDAGVQTTVTRYP
MSMEG_2875|M.smegmatis_MC2_155 YRVPAYADDLRGLPQAIVVTGECDPIRDWGERYADRLRAARVQTTLTRYP
Mflv_4562|M.gilvum_PYR-GCK YRIPAYAEDLSGLPPAIVVTGECDPIRDWGERYAQRLRDARVQTTLTRYP
MAV_3032|M.avium_104 YLVPAYAADLSGLPPAIVVTAGCDPIRDWGERYADRLRDAGVQTTVTRYP
MLBr_00314|M.leprae_Br4923 ELYEPLDHIAPGLPRTLIHVSGSEVLLHDAQLAATKLAAVGVPAEIRVWP
.*. : : .. : : . . . * . . . :
Mb1435c|M.bovis_AF2122/97 TLVHGYVGYAGVVPAATEATNRGLVALRVVLHG-----------------
Rv1400c|M.tuberculosis_H37Rv TLVHGYVGYAGVVPAATEATNRGLVALRVVLHG-----------------
MAB_2814|M.abscessus_ATCC_1997 TLIHGYLGYADIVPSATEERDLSLAALKQALHG-----------------
MMAR_1746|M.marinum_M SLTHGFLNLFPLGGGCAAATSELISALRAHLTRV----------------
MUL_1989|M.ulcerans_Agy99 SLTHGFLNLFPLGGGCAAATSELISALRAHLTRV----------------
TH_2802|M.thermoresistible__bu GMYHGFLMRYESTARGRLALAEIGALLRAKFANPLPF-------------
Mvan_2872|M.vanbaalenii_PYR-1 GIYHGFLMRSEATARGRLAMAEIGALLRAKFANPLPFTTPLRCR------
MSMEG_2875|M.smegmatis_MC2_155 GMYHGFLMRYEATARGRLALAETGALLRAKFADPLPFAG-----------
Mflv_4562|M.gilvum_PYR-GCK GMYHGFLMRPDGTARGRLAMAEIGALLRAKFAEPLPF-------------
MAV_3032|M.avium_104 GMYHGFLMRSDATARGRLAIAEIGGLLRAKFTHPLRFDVPITGRHSTPTR
MLBr_00314|M.leprae_Br4923 GQVHVFQAAAPMVPEATLSLRQISQYIREATASKASRDRQSL--------
* : ::