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RTPRCAIVWCMQARPDGPPAFTKPDAIDPALRAISRILPRGYGLHRGLKLPRALMKLAGITGRLRDVPVV AVNDAVSVRSHRPAGLPDPGPALLWIHGGGTVMGSAAQEDQYCRKLSHLAGVAVAAVDYRLAPEHPYPTP VEDCYAALLWLRQQQWVDPSRIAVAGASAGDLFAATLVQLACDRGDVEPVLQMLVYPMLDDRTGSGPNGH KRIMWSERDNQQAWQLYLAGADPSTAAPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3141 | - | - | 100% (240) | esterase/lipase |
| M. ulcerans Agy99 | MUL_1989 | lipN | 3e-22 | 37.27% (161) | lipase/esterase LipN |
| M. ulcerans Agy99 | MUL_1054 | lipW | 3e-22 | 37.93% (174) | esterase LipW |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0223c | lipW | 5e-52 | 48.84% (215) | esterase LipW |
| M. gilvum PYR-GCK | Mflv_0442 | - | 5e-53 | 50.23% (215) | alpha/beta hydrolase domain-containing protein |
| M. tuberculosis H37Rv | Rv0217c | lipW | 3e-51 | 48.37% (215) | esterase LipW |
| M. leprae Br4923 | MLBr_00314 | - | 1e-12 | 30.25% (162) | putative esterase |
| M. abscessus ATCC 19977 | MAB_0826c | - | 7e-58 | 52.51% (219) | esterase LipW |
| M. marinum M | MMAR_2621 | - | 1e-131 | 98.25% (229) | esterase/lipase |
| M. avium 104 | MAV_2513 | - | 4e-88 | 69.55% (220) | alpha/beta hydrolase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0280 | - | 1e-45 | 45.33% (225) | alpha/beta hydrolase fold |
| M. thermoresistible (build 8) | TH_2573 | - | 5e-49 | 48.13% (214) | PUTATIVE Alpha/beta hydrolase fold-3 domain protein |
| M. vanbaalenii PYR-1 | Mvan_0225 | - | 3e-50 | 48.39% (217) | alpha/beta hydrolase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3141|M.ulcerans_Agy99 MRTPRCAIVWCMQARPDGPPAFTKPDAIDPALRAISRILPRGYGLHRG--
MMAR_2621|M.marinum_M -----------MQARSDGPPAFTKPDAIDPALRAISRILPRGYGLHRG--
MAV_2513|M.avium_104 -----------MADRLP-DDAFTAPQVVDPGLRKVARFLPRGYALHRG--
Mflv_0442|M.gilvum_PYR-GCK ----------------------MHGVDFHPELRRAARMLPRQVVTPVT--
Mvan_0225|M.vanbaalenii_PYR-1 ------------MPLPHTHTERVPDIEFHPELRRSARLLPKQVITPLT--
TH_2573|M.thermoresistible__bu ----------------VARSSKLP-LDFHPDLRRLARFIPRQAVSPVT--
MSMEG_0280|M.smegmatis_MC2_155 -------------------MTATTPTRFHPDLERVARYIPRHMVNRAT--
Mb0223c|M.bovis_AF2122/97 ----------------------MSGNEVHPDLRRIAVVTPRQLVGPRT--
Rv0217c|M.tuberculosis_H37Rv ----------------------MSGNEVHPDLRRIAVVTPRQLVGPRT--
MAB_0826c|M.abscessus_ATCC_199 ----------------------MSSPDIHPDLRLAARAFPRQVGLPRT--
MLBr_00314|M.leprae_Br4923 ----------MAISAGAPVEIVESGPSIAARLASLTSRLTIRPILAVGSY
. . * : .
MUL_3141|M.ulcerans_Agy99 ---LKLPRALMKLAGITGR--LRDVPVVAVNDAVSVRSHRPAGLPD---P
MMAR_2621|M.marinum_M ---LKLPRALMKLAGITGR--LRDVPVVAVNDAVSVRLHRPTGLPD---P
MAV_2513|M.avium_104 ---LKLQRAIMNLMGNAGR--LRTVPVVAVNEHVTVRLHRPPNLAE---H
Mflv_0442|M.gilvum_PYR-GCK ---LPLLRRASRLMWRRAP-AP-DVEVLTLESGVGVRLFRPAGATR---P
Mvan_0225|M.vanbaalenii_PYR-1 ---LPFIRAASRLMWRRND-SPADVEVLTLSSGVGVRLFRPSGVAPG--R
TH_2573|M.thermoresistible__bu ---LPLMRLATRPMTRR---APRDIEVLTLSSGIGIRLFRPPGGGT----
MSMEG_0280|M.smegmatis_MC2_155 ---LPVFQRLTRLMGRR---VPPGCEVLTLPSGVGIRLFRPPASTTL--P
Mb0223c|M.bovis_AF2122/97 ---LPVMRALIVVAGLRMSRTPPDIEVLTLESGVGVRLYRPAGSNE---P
Rv0217c|M.tuberculosis_H37Rv ---LPVMRALIVVAGLRMSRTPPDIEVLTLESGVGVRLYRPAGSNE---P
MAB_0826c|M.abscessus_ATCC_199 ---LSILRASIYLTDLLPR---HGVRRIAVNDNVTVRAHVPKNLEE---P
MLBr_00314|M.leprae_Br4923 VPQLPWPFGLIDHAARVLLPVTNAARAEVNLSNTSAQLVRAAGVRPADGS
* . . : .
MUL_3141|M.ulcerans_Agy99 GPALLWIHGGGTVMGSAAQEDQYCRKLSHLAGVAVAAVDYRLAPEHPYPT
MMAR_2621|M.marinum_M GPALLWIHGGGTVMGSAAQEDQYCRKLSHLAGVAVAAVDYRLAPEHPYPT
MAV_2513|M.avium_104 APALLWTHGGGTVMGHAAQDDKYLRKLSHRTGVAIAAVEHRLAPEHPYPA
Mflv_0442|M.gilvum_PYR-GCK GPALLWIHGGGYILGDAAQDDVLCRRFAHELGATVASVDYRLAPEFPYPA
Mvan_0225|M.vanbaalenii_PYR-1 GPALLWIHGGGYVIGDAAQDDVLCRRFARELGATVASVNYRLAPEYPYPV
TH_2573|M.thermoresistible__bu GAAMLWIHGGGYVIGCAAQDDALCRRYARELDVTVAAVDYRLAPENPYPI
MSMEG_0280|M.smegmatis_MC2_155 GPALVWIHGGGYVLGSAAQDDAQCLQFARQAGVTVASVEYRLAPQNPYPA
Mb0223c|M.bovis_AF2122/97 APALLWIHAGGYVMGTAQQDDRLCLRFSSRLGITVASVDYRLAPENPYPA
Rv0217c|M.tuberculosis_H37Rv APALLWIHAGGYVMGTAQQDDRLCLRFSSRLGITVASVDYRLAPENPYPA
MAB_0826c|M.abscessus_ATCC_199 SAALLWIHGGGYVMGTARQDDFFCRKVMHETGIPVVSVDYRLAPEHPYPI
MLBr_00314|M.leprae_Br4923 GRIVLYLHGGAFLGCGANSHRRLVETLSKLADSPILVVNYRLLPKHSIGM
. ::: *.*. : * .. . .: *::** *: .
MUL_3141|M.ulcerans_Agy99 PVEDCYAALLWLRQQQWVDPSRIAVAGASAGDLFAATLVQLACDRGDVEP
MMAR_2621|M.marinum_M PVEDCYAALLWLRQQQWVDPSRIAVAGASAGGLFAATLVQLACDRGDVEP
MAV_2513|M.avium_104 PVEDCYAALLWLARQPWVDPERVAVGGASAGGLFAATLAQRAHDRNDVKI
Mflv_0442|M.gilvum_PYR-GCK PVEDCYSALKWLSALPAVDPSRVAIGGASAGGGIAAALAFLARDRGEIPL
Mvan_0225|M.vanbaalenii_PYR-1 PVEDCYSALHWLTQLPSVDPARVAIGGASAGGGLAAALALLTRDRGEIEL
TH_2573|M.thermoresistible__bu PLEDCYAALLWLTRLPTVDPQRVVIAGGSAGGGLAAALALLARDRGEVAP
MSMEG_0280|M.smegmatis_MC2_155 GLEDCFAALRWLTALPSVDPARVAIGGASAGGGLAASLALLARDRG-IDV
Mb0223c|M.bovis_AF2122/97 ALGDCYSALTWLASLPAVDPARVAIGGASAGGGLAAALALLARDRGGITP
Rv0217c|M.tuberculosis_H37Rv ALGDCYSALTWLASLPAVDPARVAIGGASAGGGLAAALALLARDRGGITP
MAB_0826c|M.abscessus_ATCC_199 PLEDCYAALRWLSVQGWIDPTRIAVGGASAGGGLAAALALLARDRGEVAP
MLBr_00314|M.leprae_Br4923 ALDDCHDGYQWLRRLG-YDPEQIVLAGDSAGGYLALALAQRLQDVGEEPA
: **. . ** ** ::.:.* ***. :* :*. * .
MUL_3141|M.ulcerans_Agy99 VLQMLVYPMLDDRTGSGP--NGHKRIMWSERDNQQAWQLYLA-------G
MMAR_2621|M.marinum_M VLQMLVYPMLDDRTGSGP--NGHKRIMWSERDNQQAWQLYLA-------G
MAV_2513|M.avium_104 AFQMLVYPMLDDRTGAQR--DGPRRLMWTESDNQLAWQWYLN-------G
Mflv_0442|M.gilvum_PYR-GCK AAQLLVYPMIDDRTVLRTGLDNPGHRLWNQAANRFGWQAYLG-------D
Mvan_0225|M.vanbaalenii_PYR-1 AAQLLVYPMIDDRTVHRKGLDHPGHRLWNQSSNRFGWRAYLG-------D
TH_2573|M.thermoresistible__bu VAQLLVYPMLDDRTLHRTDLDHPGLRLWNQSSNRFGWSAYLG-------D
MSMEG_0280|M.smegmatis_MC2_155 AAQLLVYPMLDDRSSFVPSLDHPGQRLWNQGSNRFGWKAYLG-------D
Mb0223c|M.bovis_AF2122/97 AFQLLVYPMLDDRTSIAP--ANPHYRLWNGRANRFGWRAYLG-------D
Rv0217c|M.tuberculosis_H37Rv AFQLLVYPMLDDRPSIAP--ANPHYRLWNGRANRFGWRAYLG-------D
MAB_0826c|M.abscessus_ATCC_199 AAQLLIYPMLDDRSSERTDIDGTNLRLWSGDSNRFGWDSYLG-------D
MLBr_00314|M.leprae_Br4923 ALVAISPLLQLAKKGKQAHPNAKTDAMFPPKAFDALGRLVASSAAKNKVD
. : : : :: .
MUL_3141|M.ulcerans_Agy99 ADPSTAAPA-----------------------------------------
MMAR_2621|M.marinum_M ADPSTAAPARRADLSNLPPAWIGVGTLDLFHQECLDYAARLRDAGVEVHE
MAV_2513|M.avium_104 ADPDEAAPARRKDLSGLPPAWIGVGTLDLFYPECLEYARRLREAGVPVQE
Mflv_0442|M.gilvum_PYR-GCK ADRDVAVPARRDDLAGLPPAWIGVGTLDLFHDEDLAYAERLRAAGVPCEV
Mvan_0225|M.vanbaalenii_PYR-1 ADPNEAVPARRDDLAGLPPAWIGVGTLDLFHDEDLAYAERLRVAGVQCEV
TH_2573|M.thermoresistible__bu ADPEVAVPARQTDLAGLPPAWIGVGTYDLFHDEDLAYAERLRAAGVPCEV
MSMEG_0280|M.smegmatis_MC2_155 ADPDVAVPARREDLSGLPPAWVGVGTLDLFHDEDLAYAGRLHAAGVPCEI
Mb0223c|M.bovis_AF2122/97 ADARVAVPGRRDDLGGLAPAWIGVGTHDLLHDEDLAYAERLTAAGVPCQV
Rv0217c|M.tuberculosis_H37Rv ADARVAVPGRRDDLGGLAPAWIGVGTHDLLHDEDLAYAERLTAAGVPCQV
MAB_0826c|M.abscessus_ATCC_199 ADRDIAVPGRRTDVAGLAPAWIGIGTADLFHDEDLAYAERLRTAGVPCEL
MLBr_00314|M.leprae_Br4923 DKPEELYEPLDHIAPGLPRTLIHVSGSEVLLHDAQLAATKLAAVGVPAEI
.
MUL_3141|M.ulcerans_Agy99 ----------------------------------------------
MMAR_2621|M.marinum_M QIADGAFHAFDLLAPNAQVSLGFFASQCQFLRTHLHATVSDQPQAP
MAV_2513|M.avium_104 EIVPGAFHAFDQIVDKAPISAKFFESQCDFLRGALAPNG-------
Mflv_0442|M.gilvum_PYR-GCK EVVKGAFHGFDGIAPKAEVSQSFFRSQCALLRGAFEPAAA------
Mvan_0225|M.vanbaalenii_PYR-1 MVVDGAFHGFDGIAPKADVSQSFFNSQCALLRTVFASAAP------
TH_2573|M.thermoresistible__bu EVVPGAFHGFDAIAPRAGVSRQFFDSQCAMLRGLLRPEAA------
MSMEG_0280|M.smegmatis_MC2_155 DVVHGAFHGFDGVAPKAAVSRAFRNAQCAFLKRALT----------
Mb0223c|M.bovis_AF2122/97 EVVEGAFHGFDRVAPNVGVSQRFFTSQCNSLRAALALSNRT-----
Rv0217c|M.tuberculosis_H37Rv EVVEGAFHGFDRVAPNVGVSQRFFTSQCNSLRAALALSNRT-----
MAB_0826c|M.abscessus_ATCC_199 EVVPGAFHGFDKLVPWAGVSRDFVAKACRSLLGALS----------
MLBr_00314|M.leprae_Br4923 RVWPGQVHVFQAAAPMVPEATLSLRQISQYIREATASKASRDRQSL