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M. thermoresistible (build 8) TH_0097 (-)

annotation: P-type ATPase - metal cation transport
coordinates: 181704 - 184091
length: 796

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0097--100% (796)P-type ATPase - metal cation transport
M. thermoresistible (build 8)TH_4494-1e-5527.45% (736) PUTATIVE cation-transporting ATPase Pma1
M. thermoresistible (build 8)TH_2842-6e-5425.91% (911) PUTATIVE ATPase, P-type (transporting), HAD superfamily,

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0932ctpE0.076.90% (788) metal cation transporter ATPase P-type CtpE
M. gilvum PYR-GCKMflv_1758-0.081.42% (791) ATPase, P-type (transporting), HAD superfamily, subfamily IC
M. tuberculosis H37RvRv0908ctpE0.076.90% (788) metal cation transporter ATPase P-type CtpE
M. leprae Br4923MLBr_02671-2e-4426.26% (834) putative cation transport ATPase
M. abscessus ATCC 19977MAB_0962-0.077.64% (787) cation-transporting ATPase E
M. marinum MMMAR_4622ctpE0.074.94% (790) metal cation transporter ATPase p-type CtpE
M. avium 104MAV_1031-0.076.27% (788) cation-transporting ATPase Exp7
M. smegmatis MC2 155MSMEG_5636-0.081.76% (795) P-type ATPase - metal cation transport
M. ulcerans Agy99MUL_0233ctpE0.074.43% (790) metal cation transporter ATPase p-type CtpE
M. vanbaalenii PYR-1Mvan_4989-0.080.79% (807) ATPase, P-type (transporting), HAD superfamily, subfamily IC

CLUSTAL 2.0.9 multiple sequence alignment


Mb0932|M.bovis_AF2122/97            --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4622|M.marinum_M               --------------------------------------------------
MUL_0233|M.ulcerans_Agy99           --------------------------------------------------
MAV_1031|M.avium_104                --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0097|M.thermoresistible__bu      --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02671|M.leprae_Br4923          MKIPHVTDPVSNMVGGMAQVVRASTHAATGAVNTMQMLASPVAEFAWPVV
                                                                                      

Mb0932|M.bovis_AF2122/97            --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4622|M.marinum_M               --------------------------------------------------
MUL_0233|M.ulcerans_Agy99           --------------------------------------------------
MAV_1031|M.avium_104                --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0097|M.thermoresistible__bu      --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02671|M.leprae_Br4923          QSVAKSTGRALGTGHSPNFANRVDPPVRWHNGQRVHLDLDPLLPFPRWHE
                                                                                      

Mb0932|M.bovis_AF2122/97            --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4622|M.marinum_M               --------------------------------------------------
MUL_0233|M.ulcerans_Agy99           --------------------------------------------------
MAV_1031|M.avium_104                --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0097|M.thermoresistible__bu      --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02671|M.leprae_Br4923          YAAVVEEPVRRIPGVAKGHVEGSLGRLVIELDKNADSDVVLGKVRDVVIA
                                                                                      

Mb0932|M.bovis_AF2122/97            --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4622|M.marinum_M               --------------------------------------------------
MUL_0233|M.ulcerans_Agy99           --------------------------------------------------
MAV_1031|M.avium_104                --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0097|M.thermoresistible__bu      --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02671|M.leprae_Br4923          LAADLALTGARSAPKVAPFADPGNPLAILMPLTAAVMDLVALSAAVTGWV
                                                                                      

Mb0932|M.bovis_AF2122/97            --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4622|M.marinum_M               --------------------------------------------------
MUL_0233|M.ulcerans_Agy99           --------------------------------------------------
MAV_1031|M.avium_104                --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0097|M.thermoresistible__bu      --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02671|M.leprae_Br4923          TRLPAVPQTIRAAAALVNHQPRMVSLLESRLGRVGTDIALSITTAAASGL
                                                                                      

Mb0932|M.bovis_AF2122/97            --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4622|M.marinum_M               --------------------------------------------------
MUL_0233|M.ulcerans_Agy99           --------------------------------------------------
MAV_1031|M.avium_104                --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0097|M.thermoresistible__bu      --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02671|M.leprae_Br4923          TQAVGTPLLDLACRGLQLSEAAAHQRVWRDREPQLASPKRPQAPVVPVIS
                                                                                      

Mb0932|M.bovis_AF2122/97            --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4622|M.marinum_M               --------------------------------------------------
MUL_0233|M.ulcerans_Agy99           --------------------------------------------------
MAV_1031|M.avium_104                --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0097|M.thermoresistible__bu      --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02671|M.leprae_Br4923          SAGEKSHAAGHNWTAAASNEASHLVVGGSIDAAIDTAKGSMKGPVESYVD
                                                                                      

Mb0932|M.bovis_AF2122/97            --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4622|M.marinum_M               --------------------------------------------------
MUL_0233|M.ulcerans_Agy99           --------------------------------------------------
MAV_1031|M.avium_104                --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0097|M.thermoresistible__bu      --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02671|M.leprae_Br4923          SAANGSLIAAASALLAGGGTEDAAGAILAGVPRAAHMGQQAFAATLGRGL
                                                                                      

Mb0932|M.bovis_AF2122/97            --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4622|M.marinum_M               --------------------------------------------------
MUL_0233|M.ulcerans_Agy99           --------------------------------------------------
MAV_1031|M.avium_104                --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0097|M.thermoresistible__bu      --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02671|M.leprae_Br4923          ANAGQLVLDPGALRRLDQVKVVVIDGAALRGDHRAVLLARGNTPGWDDDR
                                                                                      

Mb0932|M.bovis_AF2122/97            --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4622|M.marinum_M               --------------------------------------------------
MUL_0233|M.ulcerans_Agy99           --------------------------------------------------
MAV_1031|M.avium_104                --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0097|M.thermoresistible__bu      --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02671|M.leprae_Br4923          VYEVTDALLHGERAPEPDPDESPATGARLRWVPLQGPSATPVQGREHADL
                                                                                      

Mb0932|M.bovis_AF2122/97            --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4622|M.marinum_M               --------------------------------------------------
MUL_0233|M.ulcerans_Agy99           --------------------------------------------------
MAV_1031|M.avium_104                --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0097|M.thermoresistible__bu      --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02671|M.leprae_Br4923          VVNGECVGGVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGTEDLSASVG
                                                                                      

Mb0932|M.bovis_AF2122/97            --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4622|M.marinum_M               --------------------------------------------------
MUL_0233|M.ulcerans_Agy99           --------------------------------------------------
MAV_1031|M.avium_104                --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0097|M.thermoresistible__bu      --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02671|M.leprae_Br4923          ATHPPGTPLLKLVRELRTDRGPVLLITAVHRDFASTDTLAALAIADVGVA
                                                                                      

Mb0932|M.bovis_AF2122/97            --------------------------------------------------
Rv0908|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4622|M.marinum_M               --------------------------------------------------
MUL_0233|M.ulcerans_Agy99           --------------------------------------------------
MAV_1031|M.avium_104                --------------------------------------------------
Mflv_1758|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5636|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0097|M.thermoresistible__bu      --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02671|M.leprae_Br4923          LDDPHAATPWTADIITGTDLAAAVRILSALPVARSASESSVHLAQGGTTL
                                                                                      

Mb0932|M.bovis_AF2122/97            --------------------MTRSASATAGLTDAEVAQRVAEGKSNDIPE
Rv0908|M.tuberculosis_H37Rv         --------------------MTRSASATAGLTDAEVAQRVAEGKSNDIPE
MMAR_4622|M.marinum_M               --------------------MT-----AIGLTDAEVAARLAEGKSNDIPE
MUL_0233|M.ulcerans_Agy99           --------------------MT-----AIGLTDVEVAARLAEGKSNDIPE
MAV_1031|M.avium_104                --------------------MN------TGLTDAEVAQRVAHGQSNAVRQ
Mflv_1758|M.gilvum_PYR-GCK          -----------------MSAPS--DNLVAGLSDAEVAARVAEGKTNDVPT
MSMEG_5636|M.smegmatis_MC2_155      --------------------MT--TMAAAGLTDAEVAQRIAEGKTNDVPT
Mvan_4989|M.vanbaalenii_PYR-1       --------------------MT--VSVVTGLSEAEVAQRVAEGKTNDVPT
TH_0097|M.thermoresistible__bu      --------------------VT--TTLAPGLSDAEVAQRVAAGQTNDVPT
MAB_0962|M.abscessus_ATCC_1997      -------------------MATIEGLTISGLTAAEVAERVAQGKTNDVPS
MLBr_02671|M.leprae_Br4923          AGLLLITASAGSKSASPITLRRWFSPVNAAAATALVTGVVSASKVLRLPD
                                                                 . : . *:  :: .:   :  

Mb0932|M.bovis_AF2122/97            RVTRTVGQIVRAN---VFTRINAILG------------------------
Rv0908|M.tuberculosis_H37Rv         RVTRTVGQIVRAN---VFTRINAILG------------------------
MMAR_4622|M.marinum_M               RATRSVAQIVRAN---VFTRINAILG------------------------
MUL_0233|M.ulcerans_Agy99           RATRRVAQIVRAN---VFTRINAILG------------------------
MAV_1031|M.avium_104                RATRSITDIVRAN---VFTRINAILG------------------------
Mflv_1758|M.gilvum_PYR-GCK          RAARSVSEIIRGN---VFTRINAILG------------------------
MSMEG_5636|M.smegmatis_MC2_155      RAARTVSEIVRAN---VFTRINAILG------------------------
Mvan_4989|M.vanbaalenii_PYR-1       RAARSVSEIVRGN---VFTRINAILG------------------------
TH_0097|M.thermoresistible__bu      RAARTTGEIIRAN---VFTRINGILG------------------------
MAB_0962|M.abscessus_ATCC_1997      RAARSVSDIVRAN---VFTRINAILG------------------------
MLBr_02671|M.leprae_Br4923          PTPQPLTAWHALDPEIVYSRLAGVTQPLAVEPGTPDWRRRLDDLSYTRAL
                                     ..:        :   *::*: .:                          

Mb0932|M.bovis_AF2122/97            --------------------------VLLLIVLATGSLINGMFGLLIIA-
Rv0908|M.tuberculosis_H37Rv         --------------------------VLLLIVLATGSLINGMFGLLIIA-
MMAR_4622|M.marinum_M               --------------------------VLLLIVLATGSVINGMFGLLIIA-
MUL_0233|M.ulcerans_Agy99           --------------------------VLLLIVLATGSVINGMFGLLIIA-
MAV_1031|M.avium_104                --------------------------VLLLIVLATGSVINGMFGLLIIA-
Mflv_1758|M.gilvum_PYR-GCK          --------------------------VLFVIVLSTGSLINGAFGLLIIA-
MSMEG_5636|M.smegmatis_MC2_155      --------------------------VLFVIVLSTGSVINGAFGLLIIA-
Mvan_4989|M.vanbaalenii_PYR-1       --------------------------VLLIIVLATGSVINGAFGLLIIA-
TH_0097|M.thermoresistible__bu      --------------------------VLFLIVLSTGSIINGAFGLLIIA-
MAB_0962|M.abscessus_ATCC_1997      --------------------------VLLIIVLSTGSIINGAFGLLIIA-
MLBr_02671|M.leprae_Br4923          SPLRKPVTKLARLASATRQEFADPLTPILAVGAAASAIVGSNIDALLVAG
                                                               :: :  ::.:::.. :. *::* 

Mb0932|M.bovis_AF2122/97            ----NSVIGMVQEIRAKQTLDKLAIIG---------QAKPLVRRQSGT--
Rv0908|M.tuberculosis_H37Rv         ----NSVIGMVQEIRAKQTLDKLAIIG---------QAKPLVRRQSGT--
MMAR_4622|M.marinum_M               ----NSIIGMIQELRAKQTLDNLAILG---------QAKPLVRRQSGT--
MUL_0233|M.ulcerans_Agy99           ----NSIIGMIQELRAKQTLDNLAILG---------QAKPLVRRQSGT--
MAV_1031|M.avium_104                ----NSVVGMVQEIRAKQTLDKLAIVG---------QAKPMVRRQSGT--
Mflv_1758|M.gilvum_PYR-GCK          ----NSAIGIIQELRAKQTLDKLAIVG---------QAKPLVRRQSGT--
MSMEG_5636|M.smegmatis_MC2_155      ----NSAIGIIQEIRAKQTLDKLAIVG---------QAKPTVRRQSGT--
Mvan_4989|M.vanbaalenii_PYR-1       ----NSAIGIIQELRAKQTLDKLAIVG---------QAKPLVRRKSGTGS
TH_0097|M.thermoresistible__bu      ----NSAVGMIQELRAKRTLDNLAIIG---------QAKPMVRRRSGT--
MAB_0962|M.abscessus_ATCC_1997      ----NSAVGIIQELRAKQILDKLAIVG---------QTRPLVRRDGAA--
MLBr_02671|M.leprae_Br4923          VMTVNAITGGVQRLRAEAAAAELFAEQDQLVRRVVVPAVATTRRRLEAAQ
                                        *:  * :*.:**:    :*              : . .**   :  

Mb0932|M.bovis_AF2122/97            -----RTRSTNEVVLDDIIELGPGDQVVVDGEVVEEENLEIDESLLTGEA
Rv0908|M.tuberculosis_H37Rv         -----RTRSTNEVVLDDIIELGPGDQVVVDGEVVEEENLEIDESLLTGEA
MMAR_4622|M.marinum_M               -----RTMSPSEVVLDDVIELGPGDQVVVDGEVLEQDNLEIDESLLTGEA
MUL_0233|M.ulcerans_Agy99           -----RTMSPSEVVLDDVIELGPGDQVVVDGEVLEQDNLEIDESLLTGEA
MAV_1031|M.avium_104                -----HALPPDEVVLDDIIELGPGDQVVVDGEIVEEANLEVDESLLTGEA
Mflv_1758|M.gilvum_PYR-GCK          -----QPMPPSEVVLDDVIELGPGDQIVVDGVILEETNLEVDESLLTGEA
MSMEG_5636|M.smegmatis_MC2_155      -----RAVLPSEVVLDDIIELGPGDQIVVDGEVVEETNLEVDESLLTGEA
Mvan_4989|M.vanbaalenii_PYR-1       VS---LPLAPSEVVLDDVIELGPGDQIVVDGVILEESNLEIDESLLTGEA
TH_0097|M.thermoresistible__bu      -----RALAPSEVVLDDIIELGPGDQIVVDGEVVEAANLEIDESLLTGEA
MAB_0962|M.abscessus_ATCC_1997      -----TALAPNEVVLDDIIELGPGDQIVVDGEVIEESALEIDESLLTGEA
MLBr_02671|M.leprae_Br4923          HATRTVTVSAKSLRAGDVIDLAAPEVVPADARVLVAEDLEVDESLLTGES
                                          .  ...:  .*:*:*.. : : .*. ::    **:********:

Mb0932|M.bovis_AF2122/97            DPIAKDAG----DTVMSGSFVVSGAGAYR-ATKVGSEAYAAKLAAEASKF
Rv0908|M.tuberculosis_H37Rv         DPIAKDAG----DTVMSGSFVVSGAGAYR-ATKVGSEAYAAKLAAEASKF
MMAR_4622|M.marinum_M               DSIAKHVG----EQVMSGSFVVAGSGAYR-ATKVGHEAYAAKLAAEASKF
MUL_0233|M.ulcerans_Agy99           DSIAKHVG----EQVMSGSFVVAGSGAYR-ATKVGHEAYAAKLAAEASKF
MAV_1031|M.avium_104                DPIAKAVG----DSVMSGSFVVAGTGAYR-ATRVGSQAYAARLAEEASKF
Mflv_1758|M.gilvum_PYR-GCK          DAIAKDAG----DHVMSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF
MSMEG_5636|M.smegmatis_MC2_155      DPIAKDAG----DPVMSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF
Mvan_4989|M.vanbaalenii_PYR-1       DAIAKGID----DHVMSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF
TH_0097|M.thermoresistible__bu      DPIPKEPG----DQVMSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF
MAB_0962|M.abscessus_ATCC_1997      DAIEKTIG----SQVLSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF
MLBr_02671|M.leprae_Br4923          LPVDKRVDPVAINDADRASMLFEGSAIVAGHARAIVVATGVGTAAHRAIS
                                     .: *  .    . .  .*::. *:.     ::.   * ..  * . :  

Mb0932|M.bovis_AF2122/97            TLVKSELRNGINRILQFITYLLVP---AGLLTIYTQLFTTHVGWRESVLR
Rv0908|M.tuberculosis_H37Rv         TLVKSELRNGINRILQFITYLLVP---AGLLTIYTQLFTTHVGWRESVLR
MMAR_4622|M.marinum_M               TLVKSELRSGINKILQFITYLLIP---AGLLTIYTQLFTTHAGWRDSVLR
MUL_0233|M.ulcerans_Agy99           TLVKSELRSGINKILQFITYLLIP---AGLLTIYTQLFTTHAGWRDSVLR
MAV_1031|M.avium_104                TLVKSELRNGINRILQFITYLLVP---AGLLTIYTQLFTTHAGWQKSVLR
Mflv_1758|M.gilvum_PYR-GCK          TLVRSELRNGINQILRFITYLLIP---AGALIIYTQLFTTDSGWRESVLR
MSMEG_5636|M.smegmatis_MC2_155      TLVKSELRNGINKILQFITYLLVP---AGLLTIYTQLFTTDAGWREAVLR
Mvan_4989|M.vanbaalenii_PYR-1       TLVKSELRNGINKILQFITYLLVP---AGALTIYTQLFTTDAGWRRAVLA
TH_0097|M.thermoresistible__bu      TLVKSDLRNGINTILRFITYLLIP---AGLLTIYTQLFTTDADWRRAVLA
MAB_0962|M.abscessus_ATCC_1997      TLVHSELRNGINKILQFITYLLLP---AGALIIYTQLFTTDDSWQESVLR
MLBr_02671|M.leprae_Br4923          AVADVEVSAGVQARLRELTSKVLPLTLAGGAAVTGLALLRRASLRQAVAD
                                    ::.  ::  *::  *: :*  ::*   **   :    :    . : :*  

Mb0932|M.bovis_AF2122/97            MVGALVPMVPEGLVLMTSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVV
Rv0908|M.tuberculosis_H37Rv         MVGALVPMVPEGLVLMTSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVV
MMAR_4622|M.marinum_M               TVGALVPMVPEGLVLMTSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVV
MUL_0233|M.ulcerans_Agy99           TVGALVPMVPEGLVLITSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVV
MAV_1031|M.avium_104                TVGALVPMVPEGLVLLTSVAFAVGVVRLGQRRCLVQELPAIEGLARVDVV
Mflv_1758|M.gilvum_PYR-GCK          MVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVNELPAIEGLARVDVV
MSMEG_5636|M.smegmatis_MC2_155      MVGALVPMVPEGLVLMTSIAFAVGVVRLGRRQCLVNELPAIEGLARVDVV
Mvan_4989|M.vanbaalenii_PYR-1       MVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVNELPAIEGLARVDVV
TH_0097|M.thermoresistible__bu      MVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVNELPAIEGLARVDVV
MAB_0962|M.abscessus_ATCC_1997      MVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVQELPAIEGLARVDTV
MLBr_02671|M.leprae_Br4923          GVAIAVAAVPEGLPLVATLSQLAAAQRLTAKGALVRSPRTIEALGRVDTI
                                     *.  *. ***** *:::::  ... **  : .**..  :**.*.***.:

Mb0932|M.bovis_AF2122/97            CADKTGTLTESGMRVCEVEELDG--------AGRQESVADVLAALAAADA
Rv0908|M.tuberculosis_H37Rv         CADKTGTLTESGMRVCEVEELDG--------AGRQESVADVLAALAAADA
MMAR_4622|M.marinum_M               CADKTGTLTETGMRVSDVDELI---------ADQHGAVADVLAFLAAADA
MUL_0233|M.ulcerans_Agy99           CADKTGTLTETGMRVSDVDELI---------ADQHGAVADVLAFLAAADA
MAV_1031|M.avium_104                CADKTGTLTESGMRVARVDELD---------GSGHDRIADVLAALAAADP
Mflv_1758|M.gilvum_PYR-GCK          CADKTGTLTENGMRVSDLKVLES------------RSVTDVLAQLAADDA
MSMEG_5636|M.smegmatis_MC2_155      CADKTGTLTENGMRVSDLKSLTE------------GHVADVLAQLASDDA
Mvan_4989|M.vanbaalenii_PYR-1       CADKTGTLTENGMRVSEVKRIDARPTGEERSDRGMGTVADVLAQLAADDP
TH_0097|M.thermoresistible__bu      CADKTGTLTENGMRVAELRHLTE--------SGDRSRVEAVLASLAADDP
MAB_0962|M.abscessus_ATCC_1997      CADKTGTLTENGMRLADVHFPDR---------DGDEDALAVLAQLAADDP
MLBr_02671|M.leprae_Br4923          CFDKTGTLTENRLRVVCAVPNTR-MPHDPLPDITDPHSAAVLRDAARAST
                                    * ********. :*:                         **   *  ..

Mb0932|M.bovis_AF2122/97            RPNAS------------MQAIAEAFHSPPGWVVAANAPFKSATKWSGVSF
Rv0908|M.tuberculosis_H37Rv         RPNAS------------MQAIAEAFHSPPGWVVAANAPFKSATKWSGVSF
MMAR_4622|M.marinum_M               RPNAS------------MQAIAQAFPSPPDWTPTATAPFKSATKWSGISF
MUL_0233|M.ulcerans_Agy99           RPNAS------------MQAIAQAFPSPPDWTSTATAPFKSATKWSGISF
MAV_1031|M.avium_104                RPNAS------------MRAIAQTYSRPPGWTVTATAPFKSATKWSGVSF
Mflv_1758|M.gilvum_PYR-GCK          RPNAS------------MAAIAEAYAVPPGWTATATAPFKSATKWSGASY
MSMEG_5636|M.smegmatis_MC2_155      RPNAS------------MAAIAEAYQTPPGWSATATAPFKSATKWSGTSY
Mvan_4989|M.vanbaalenii_PYR-1       RPNAS------------MAAIAEAYKMPPGWTATATAPFKSATKWSGTSY
TH_0097|M.thermoresistible__bu      RPNAS------------MQAIAEAYPDPPGWAATAIAPFKSALKWSGVSY
MAB_0962|M.abscessus_ATCC_1997      RPNAS------------IAAIAEAYDTPPGWETTAIAPFSSAKKWSGASY
MLBr_02671|M.leprae_Br4923          QPHDGQGHTHATDEAILTAASSLNSHTDSTWSLIAEVPFESSRGYAAAIG
                                    :*: .              * :      . *   * .**.*:  ::.   

Mb0932|M.bovis_AF2122/97            RDHGN-----WVIGAPDVLLDPASVAARQAERIGAQ---------GLRVL
Rv0908|M.tuberculosis_H37Rv         RDHGN-----WVIGAPDVLLDPASVAARQAERIGAQ---------GLRVL
MMAR_4622|M.marinum_M               RDHGN-----WVIGAPDVLLDSASDAAREAERIGAQ---------GLRIL
MUL_0233|M.ulcerans_Agy99           RDHGN-----WVIGAPDVLLDSASEAAREAERIGAQ---------GLRIL
MAV_1031|M.avium_104                AGHGD-----WVMGAPDVLLDSCSAAAGQAERLGAQ---------GLRVL
Mflv_1758|M.gilvum_PYR-GCK          AEHGN-----WVIGAPDVLLDPASPVAEDAERIGAR---------GLRVL
MSMEG_5636|M.smegmatis_MC2_155      GEHGN-----WVIGAPDVLLDPASPVAEEAERIGAQ---------GLRVL
Mvan_4989|M.vanbaalenii_PYR-1       GDHGN-----WVIGAPDVLLDPTSTAAEEAERIGAQ---------GLRVL
TH_0097|M.thermoresistible__bu      GEHGN-----WVIGAPDVLLDPASPAARQAEEIGSR---------GLRVL
MAB_0962|M.abscessus_ATCC_1997      GEHGN-----WVIGAPDVLLDPADAIATAAEEIGAR---------GLRVL
MLBr_02671|M.leprae_Br4923          ITGNGKAPMLMLKGAPEKILPRCRFADPEADVAHAESLVRHLAEQGLRVL
                                       ..      : ***: :*         *:   :.         ***:*

Mb0932|M.bovis_AF2122/97            LLAAGSVAVDHA-----------QAPGQVTPVALVVLEQKVRPDARETLD
Rv0908|M.tuberculosis_H37Rv         LLAAGSVAVDHA-----------QAPGQVTPVALVVLEQKVRPDARETLD
MMAR_4622|M.marinum_M               LLGVADVAVDDP-----------CAPGQVTPAALVILEQKVRPDARETME
MUL_0233|M.ulcerans_Agy99           LLGVAAVAVDDP-----------CAPGQVTPAALVILEQKVRPDARETME
MAV_1031|M.avium_104                LLGAADRAVDHP-----------DAPGPITPVALVVLEQKVRPDARETLD
Mflv_1758|M.gilvum_PYR-GCK          LLGSSDRPVDAP-----------DAPGVVTPAALVVLEQRVRPDARGTLD
MSMEG_5636|M.smegmatis_MC2_155      LLGSSDRSVDAP-----------DAPGVVTPAALVVLEQRIRPDAGDTLD
Mvan_4989|M.vanbaalenii_PYR-1       LLGSSDRSVDAP-----------DAPGTVTPSALVVLEQRIRPDARDTLD
TH_0097|M.thermoresistible__bu      LLGSSDLPVDHP-----------QAPGAVTPVALVVLEQRIRSDARDTLE
MAB_0962|M.abscessus_ATCC_1997      LLASAELSVDDA-----------HAPGAVTPRALVVLEQKIRPDARETLD
MLBr_02671|M.leprae_Br4923          AVAQCSWGHDTTDDNDTDADAVDAAAHDLELVGYIGLADTARPSSRPLIE
                                     :.      * .            *.  :   . : * :  *..:   ::

Mb0932|M.bovis_AF2122/97            YFAVQNVSVKVISGDNAVSVGAVADRLGLHGEAMDAR---ALPTGREELA
Rv0908|M.tuberculosis_H37Rv         YFAVQNVSVKVISGDNAVSVGAVADRLGLHGEAMDAR---ALPTGREELA
MMAR_4622|M.marinum_M               YFAAQNVSVKVISGDNAVSVGAVAAKLGLQVQTMDAR---QLPSEQPELA
MUL_0233|M.ulcerans_Agy99           YFAAQNVSVKVISGDNAVSVGAVAAKLGLQGQTMDAR---QLPSEQPELA
MAV_1031|M.avium_104                YFADQGVSVKVLSGDNAVSVGAVAGELGLHGETLDAR---QLPSDLAQLA
Mflv_1758|M.gilvum_PYR-GCK          YFASQHVAIKVISGDNAVSVGAVAGSLGLQGETMDAR---RLPEQQDELA
MSMEG_5636|M.smegmatis_MC2_155      YFASQHVSVKVISGDNAVSVGAVAGKLGLHGETMDAR---RLPEQPEKLA
Mvan_4989|M.vanbaalenii_PYR-1       YFASQKVSVKVISGDNAVSVGAVAGSLGLGGETMDAR---RLPDQPDALA
TH_0097|M.thermoresistible__bu      YFASQQVSIKVISGDNAASVGAVSESLGLEGEAIDAR---RLPEDPDELA
MAB_0962|M.abscessus_ATCC_1997      YFASQHVSIKVISGDNAVSVSAVAQTLGLTGAAVDAR---TLPTDTDKLA
MLBr_02671|M.leprae_Br4923          ALVTAGRNVVLITGDHPITARAIAQQLGLRSDARVVNGTELIGLDEDACA
                                     :.     : :::**:. :. *::  ***   :  ..    :       *

Mb0932|M.bovis_AF2122/97            DTLDSYTSFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG
Rv0908|M.tuberculosis_H37Rv         DTLDSYTSFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG
MMAR_4622|M.marinum_M               DVLDTYTTFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG
MUL_0233|M.ulcerans_Agy99           DVLDTYITFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG
MAV_1031|M.avium_104                DMLDTYTTFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG
Mflv_1758|M.gilvum_PYR-GCK          ETLEECTTFGRVRPDQKRAMVHALQSRGHTVAMTGDGVNDVLALKDADIG
MSMEG_5636|M.smegmatis_MC2_155      ETLEECTTFGRVRPDQKRAMVHALQSRGHTVAMTGDGVNDVLALKDSDIG
Mvan_4989|M.vanbaalenii_PYR-1       DTLEQCTTFGRVRPDQKRAMVHALQSRGHTVAMTGDGVNDVLALKDADIG
TH_0097|M.thermoresistible__bu      DTLQRYTTFGRVRPDQKRSMVHALQSRGHTVAMTGDGVNDVLALKDADIG
MAB_0962|M.abscessus_ATCC_1997      ATLADATTFGRVRPDQKRAMVKALQSHGHTVAMTGDGVNDVLALKDADIG
MLBr_02671|M.leprae_Br4923          ELAADVQVFARVSPEQKVQIVAALQRCGQVTAMVGDGANDAAAIRMADVG
                                            *.** *:**  :* ***  *:..**.***.**. *:: :*:*

Mb0932|M.bovis_AF2122/97            VAMGS-GSPASRAVAQIVLLNNRFATLPHVVGEGRRVIGNIERVANLFLT
Rv0908|M.tuberculosis_H37Rv         VAMGS-GSPASRAVAQIVLLNNRFATLPHVVGEGRRVIGNIERVANLFLT
MMAR_4622|M.marinum_M               VAMGT-GSPASRAVAQIVLLDNRFATLPYVVGEGRRVIGNIERVANLFLT
MUL_0233|M.ulcerans_Agy99           VAMGT-GSPASRAVAQIVLLDNRFATLPYVVGEGRRVIRNIERVANLFLT
MAV_1031|M.avium_104                VAMGA-GSPASRAVAQIVLLDNRFATLPYVVGEGRRVIGNIERVANLFLT
Mflv_1758|M.gilvum_PYR-GCK          VAMGS-GSSASRAVAQIVLLDNKFATLPYVVGEGRRVIGNIERVSNLFLT
MSMEG_5636|M.smegmatis_MC2_155      VAMGS-GSSASRAVAQIVLLDNKFATLPYVVGEGRRVIGNIERVSNLFLT
Mvan_4989|M.vanbaalenii_PYR-1       VAMGS-GSSASRAVAQIVLLDNKFATLPYVVGEGRRVIGNIERVSNLFLT
TH_0097|M.thermoresistible__bu      VAMGS-GSPATRAVAQIVLLDNKFATLPHVVAEGRRVIGNIERVSNLFLT
MAB_0962|M.abscessus_ATCC_1997      VAMGA-GSSASRAVAQIVLLDNKFATLPYVVAEGRRVIGNIERVSNLFLT
MLBr_02671|M.leprae_Br4923          IGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMWAGVRDAVTILVG
                                    :.:.  **.*:*..*:*** :: :..*  .: *** :  .:. . .::: 

Mb0932|M.bovis_AF2122/97            KTVYSVLLALLVGIECLIAIPLRRDPLLFP------FQPIHVTIAAWFT-
Rv0908|M.tuberculosis_H37Rv         KTVYSVLLALLVGIECLIAIPLRRDPLLFP------FQPIHVTIAAWFT-
MMAR_4622|M.marinum_M               KTVYSALLALLVGIECLFAKPLGADPLLYP------FQPIHVTIAAWFT-
MUL_0233|M.ulcerans_Agy99           KAVYSALLALLVGIECLFAKPLGADPLLYP------FQPIHVTIAAWFT-
MAV_1031|M.avium_104                KTVYSVLLALLVGLECLFAKALKADPLLYP------FQPIHVTVAAWFT-
Mflv_1758|M.gilvum_PYR-GCK          KTVYSVLLAVLVGLAGLSAEIFDTDPLLFP------FQPIHVTIAAWFT-
MSMEG_5636|M.smegmatis_MC2_155      KTVYSVLLAILVGIGGLSAKIFGTDPLLFP------FQPIHVTIAAWFT-
Mvan_4989|M.vanbaalenii_PYR-1       KTVYSVLLAVLVGLGGLSAKLFGSDPLLFP------FQPIHVTIAAWFT-
TH_0097|M.thermoresistible__bu      KTVYSVLLAVLVGLGGLASVFFEADPLLFP------FQPIHVTIAAWFT-
MAB_0962|M.abscessus_ATCC_1997      KTVYSVLLALTVGLAGLGSKIFHYGAVPFP------FQPIHVTIAAWFT-
MLBr_02671|M.leprae_Br4923          GNVGEVVFTIIGTVFGAGRAPVGTRQLLLVNLLTDMFPALSIAVTSQYEE
                                      * ..::::   :       .    :         * .: ::::: :  

Mb0932|M.bovis_AF2122/97            IGIPAFILSLAPNNER------AYPGFVRRVMTSAVPFGLVIGVATFVTY
Rv0908|M.tuberculosis_H37Rv         IGIPAFILSLAPNNER------AYPGFVRRVMTSAVPFGLVIGVATFVTY
MMAR_4622|M.marinum_M               IGIPSFILSLAPNDER------AYPGFVRRVLTSALPSGLVVGVATFVSY
MUL_0233|M.ulcerans_Agy99           IGIPSFILSLAPNDER------AYPGFVRRVLTSALPSGLVVGVATFVSY
MAV_1031|M.avium_104                IGIPSFILSLAPNNER------AHPGFVRRVLSSALPSGLIVGAATFASY
Mflv_1758|M.gilvum_PYR-GCK          IGIPAFVLSLAPNNER------AHPGFVRRVMTAALPSGVVVGIATFTSY
MSMEG_5636|M.smegmatis_MC2_155      IGIPAFILSLAPNNER------AKTGFVRRVMTAALPSGLVVGTATFVSY
Mvan_4989|M.vanbaalenii_PYR-1       IGIPAFVLSLAPNNER------AHPGFVRRVMTSALPSGIVVGAATFTSY
TH_0097|M.thermoresistible__bu      IGIPAFILSLAPNTER------AKPHFVRRVMTSALPSGITIGIATFTSY
MAB_0962|M.abscessus_ATCC_1997      IGIPAFILSLAPNNER------AQTGFVRRVMLSAIPSGLTVGIATFLSY
MLBr_02671|M.leprae_Br4923          PGEDEYQTDEEADEARRTHQHEVLTGPTPSLDAPLMRQIVNRGVVTAAGA
                                     *   :  .  .:  *      . .  .  :  . :   :  * .*    

Mb0932|M.bovis_AF2122/97            LAAYQGRYASWQEQEQASTAALITLLMTALWVLAVIARPYQWWRLALVLA
Rv0908|M.tuberculosis_H37Rv         LAAYQGRYASWQEQEQASTAALITLLMTALWVLAVIARPYQWWRLALVLA
MMAR_4622|M.marinum_M               LTAYPGRHSTWQEQTQASTAALITLLVTALWVLAVVARPYRWWRLGLVIA
MUL_0233|M.ulcerans_Agy99           LTAYPGRHSTWQEQTQASTAALITLLVTALWVLAVVARPYRWWRLGLVIA
MAV_1031|M.avium_104                LVAYHGRHATFQQQDQASTAALITLLVTALWVLAVVARPYQWWRVALVIA
Mflv_1758|M.gilvum_PYR-GCK          LLAYQGRAATETEQTQASTAALITLLVAALWVLAVVARPYEWWRVALVSI
MSMEG_5636|M.smegmatis_MC2_155      LVAYQGREATPVEQTQASTAALITLLASSLWVLAVVARPYQWWRVLLVAC
Mvan_4989|M.vanbaalenii_PYR-1       LLAYQGRAATEAEQTQASTAALITLLVAGVWVLSVVARPYEWWRVALVAV
TH_0097|M.thermoresistible__bu      LIAYQGREATAVQQTQASTAALITLLVAALWVLAVVARPYQWWRVALVLV
MAB_0962|M.abscessus_ATCC_1997      LLARQILHVSG-NSTQASTAALITELVAAVWVLAVVARPYQWWRVALVAL
MLBr_02671|M.leprae_Br4923          TTAWAIGRWTPGTERRTATMG-LTALVTTQLAQTLLTRRHSPLVVATALG
                                      *      :   . :::* . :* * :   . ::::* :    :  .  

Mb0932|M.bovis_AF2122/97            SGLAYVVIFSLPLAREKFLLDAS-NLATTSIALAVGVVGAATIEAMWWIR
Rv0908|M.tuberculosis_H37Rv         SGLAYVVIFSLPLAREKFLLDAS-NLATTSIALAVGVVGAATIEAMWWIR
MMAR_4622|M.marinum_M               CGLAYVAIFSLPLAQRKFFLDPS-NLATTSIALGIGLLGAALIEAMWWLR
MUL_0233|M.ulcerans_Agy99           CGLAYVAIFSLPLAQRKFFLDPS-NLATTSIALGIGVLGAALIEAMWWLR
MAV_1031|M.avium_104                SGLAYVVIFSLPLARKAFLLDPS-NVVVTLSALGIGVLGAAAIEAAWWIR
Mflv_1758|M.gilvum_PYR-GCK          SALAYVVIFSIPAARELFILDPT-NMTTTSTALAIGIAAAAAIEVLWWVQ
MSMEG_5636|M.smegmatis_MC2_155      SMLAYVLIFSIPLAQELFMLDPT-NMKVTSVALGIGLAGAALIEVLWWVQ
Mvan_4989|M.vanbaalenii_PYR-1       SGLAYVVIFSIPLARELFILDPS-NTALTSMALGIGLAAAVAIEVIWWVQ
TH_0097|M.thermoresistible__bu      SMLAYVVIFAIPLARDVFMLDPS-NVAVTATAFGIGVIAAAVIEAAWWVQ
MAB_0962|M.abscessus_ATCC_1997      SGLGYVAIFAIPLARKAFMLDPG-NLAVTGPALGIGIAAAAVIEAVWWLQ
MLBr_02671|M.leprae_Br4923          SAGVLIGIIQTPVISQFFGCTPLGPIAWSGVITATAGATAVSVLAPQWLN
                                    .    : *:  *     *   .      :    . .   *. : .  *:.

Mb0932|M.bovis_AF2122/97            SRMLGVKPRVWR----
Rv0908|M.tuberculosis_H37Rv         SRMLGVKPRVWR----
MMAR_4622|M.marinum_M               ARALGLRPRVWR----
MUL_0233|M.ulcerans_Agy99           ARALGLRPRVWR----
MAV_1031|M.avium_104                AKMLGVRPRVWR----
Mflv_1758|M.gilvum_PYR-GCK          GHVLGERRRLWRAADG
MSMEG_5636|M.smegmatis_MC2_155      GRVLGEERRVWR----
Mvan_4989|M.vanbaalenii_PYR-1       GRVLGEHRRLWRVRER
TH_0097|M.thermoresistible__bu      GRMLGETRRLWK----
MAB_0962|M.abscessus_ATCC_1997      GKWSGQPRHFWATGDD
MLBr_02671|M.leprae_Br4923          -KAFGIAQLNQE----
                                     :  *