For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_0097 | - | - | 100% (796) | P-type ATPase - metal cation transport |
M. thermoresistible (build 8) | TH_4494 | - | 1e-55 | 27.45% (736) | PUTATIVE cation-transporting ATPase Pma1 |
M. thermoresistible (build 8) | TH_2842 | - | 6e-54 | 25.91% (911) | PUTATIVE ATPase, P-type (transporting), HAD superfamily, |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0932 | ctpE | 0.0 | 76.90% (788) | metal cation transporter ATPase P-type CtpE |
M. gilvum PYR-GCK | Mflv_1758 | - | 0.0 | 81.42% (791) | ATPase, P-type (transporting), HAD superfamily, subfamily IC |
M. tuberculosis H37Rv | Rv0908 | ctpE | 0.0 | 76.90% (788) | metal cation transporter ATPase P-type CtpE |
M. leprae Br4923 | MLBr_02671 | - | 2e-44 | 26.26% (834) | putative cation transport ATPase |
M. abscessus ATCC 19977 | MAB_0962 | - | 0.0 | 77.64% (787) | cation-transporting ATPase E |
M. marinum M | MMAR_4622 | ctpE | 0.0 | 74.94% (790) | metal cation transporter ATPase p-type CtpE |
M. avium 104 | MAV_1031 | - | 0.0 | 76.27% (788) | cation-transporting ATPase Exp7 |
M. smegmatis MC2 155 | MSMEG_5636 | - | 0.0 | 81.76% (795) | P-type ATPase - metal cation transport |
M. ulcerans Agy99 | MUL_0233 | ctpE | 0.0 | 74.43% (790) | metal cation transporter ATPase p-type CtpE |
M. vanbaalenii PYR-1 | Mvan_4989 | - | 0.0 | 80.79% (807) | ATPase, P-type (transporting), HAD superfamily, subfamily IC |
CLUSTAL 2.0.9 multiple sequence alignment Mb0932|M.bovis_AF2122/97 -------------------------------------------------- Rv0908|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4622|M.marinum_M -------------------------------------------------- MUL_0233|M.ulcerans_Agy99 -------------------------------------------------- MAV_1031|M.avium_104 -------------------------------------------------- Mflv_1758|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5636|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4989|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0097|M.thermoresistible__bu -------------------------------------------------- MAB_0962|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02671|M.leprae_Br4923 MKIPHVTDPVSNMVGGMAQVVRASTHAATGAVNTMQMLASPVAEFAWPVV Mb0932|M.bovis_AF2122/97 -------------------------------------------------- Rv0908|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4622|M.marinum_M -------------------------------------------------- MUL_0233|M.ulcerans_Agy99 -------------------------------------------------- MAV_1031|M.avium_104 -------------------------------------------------- Mflv_1758|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5636|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4989|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0097|M.thermoresistible__bu -------------------------------------------------- MAB_0962|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02671|M.leprae_Br4923 QSVAKSTGRALGTGHSPNFANRVDPPVRWHNGQRVHLDLDPLLPFPRWHE Mb0932|M.bovis_AF2122/97 -------------------------------------------------- Rv0908|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4622|M.marinum_M -------------------------------------------------- MUL_0233|M.ulcerans_Agy99 -------------------------------------------------- MAV_1031|M.avium_104 -------------------------------------------------- Mflv_1758|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5636|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4989|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0097|M.thermoresistible__bu -------------------------------------------------- MAB_0962|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02671|M.leprae_Br4923 YAAVVEEPVRRIPGVAKGHVEGSLGRLVIELDKNADSDVVLGKVRDVVIA Mb0932|M.bovis_AF2122/97 -------------------------------------------------- Rv0908|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4622|M.marinum_M -------------------------------------------------- MUL_0233|M.ulcerans_Agy99 -------------------------------------------------- MAV_1031|M.avium_104 -------------------------------------------------- Mflv_1758|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5636|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4989|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0097|M.thermoresistible__bu -------------------------------------------------- MAB_0962|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02671|M.leprae_Br4923 LAADLALTGARSAPKVAPFADPGNPLAILMPLTAAVMDLVALSAAVTGWV Mb0932|M.bovis_AF2122/97 -------------------------------------------------- Rv0908|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4622|M.marinum_M -------------------------------------------------- MUL_0233|M.ulcerans_Agy99 -------------------------------------------------- MAV_1031|M.avium_104 -------------------------------------------------- Mflv_1758|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5636|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4989|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0097|M.thermoresistible__bu -------------------------------------------------- MAB_0962|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02671|M.leprae_Br4923 TRLPAVPQTIRAAAALVNHQPRMVSLLESRLGRVGTDIALSITTAAASGL Mb0932|M.bovis_AF2122/97 -------------------------------------------------- Rv0908|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4622|M.marinum_M -------------------------------------------------- MUL_0233|M.ulcerans_Agy99 -------------------------------------------------- MAV_1031|M.avium_104 -------------------------------------------------- Mflv_1758|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5636|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4989|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0097|M.thermoresistible__bu -------------------------------------------------- MAB_0962|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02671|M.leprae_Br4923 TQAVGTPLLDLACRGLQLSEAAAHQRVWRDREPQLASPKRPQAPVVPVIS Mb0932|M.bovis_AF2122/97 -------------------------------------------------- Rv0908|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4622|M.marinum_M -------------------------------------------------- MUL_0233|M.ulcerans_Agy99 -------------------------------------------------- MAV_1031|M.avium_104 -------------------------------------------------- Mflv_1758|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5636|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4989|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0097|M.thermoresistible__bu -------------------------------------------------- MAB_0962|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02671|M.leprae_Br4923 SAGEKSHAAGHNWTAAASNEASHLVVGGSIDAAIDTAKGSMKGPVESYVD Mb0932|M.bovis_AF2122/97 -------------------------------------------------- Rv0908|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4622|M.marinum_M -------------------------------------------------- MUL_0233|M.ulcerans_Agy99 -------------------------------------------------- MAV_1031|M.avium_104 -------------------------------------------------- Mflv_1758|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5636|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4989|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0097|M.thermoresistible__bu -------------------------------------------------- MAB_0962|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02671|M.leprae_Br4923 SAANGSLIAAASALLAGGGTEDAAGAILAGVPRAAHMGQQAFAATLGRGL Mb0932|M.bovis_AF2122/97 -------------------------------------------------- Rv0908|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4622|M.marinum_M -------------------------------------------------- MUL_0233|M.ulcerans_Agy99 -------------------------------------------------- MAV_1031|M.avium_104 -------------------------------------------------- Mflv_1758|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5636|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4989|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0097|M.thermoresistible__bu -------------------------------------------------- MAB_0962|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02671|M.leprae_Br4923 ANAGQLVLDPGALRRLDQVKVVVIDGAALRGDHRAVLLARGNTPGWDDDR Mb0932|M.bovis_AF2122/97 -------------------------------------------------- Rv0908|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4622|M.marinum_M -------------------------------------------------- MUL_0233|M.ulcerans_Agy99 -------------------------------------------------- MAV_1031|M.avium_104 -------------------------------------------------- Mflv_1758|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5636|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4989|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0097|M.thermoresistible__bu -------------------------------------------------- MAB_0962|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02671|M.leprae_Br4923 VYEVTDALLHGERAPEPDPDESPATGARLRWVPLQGPSATPVQGREHADL Mb0932|M.bovis_AF2122/97 -------------------------------------------------- Rv0908|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4622|M.marinum_M -------------------------------------------------- MUL_0233|M.ulcerans_Agy99 -------------------------------------------------- MAV_1031|M.avium_104 -------------------------------------------------- Mflv_1758|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5636|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4989|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0097|M.thermoresistible__bu -------------------------------------------------- MAB_0962|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02671|M.leprae_Br4923 VVNGECVGGVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGTEDLSASVG Mb0932|M.bovis_AF2122/97 -------------------------------------------------- Rv0908|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4622|M.marinum_M -------------------------------------------------- MUL_0233|M.ulcerans_Agy99 -------------------------------------------------- MAV_1031|M.avium_104 -------------------------------------------------- Mflv_1758|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5636|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4989|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0097|M.thermoresistible__bu -------------------------------------------------- MAB_0962|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02671|M.leprae_Br4923 ATHPPGTPLLKLVRELRTDRGPVLLITAVHRDFASTDTLAALAIADVGVA Mb0932|M.bovis_AF2122/97 -------------------------------------------------- Rv0908|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4622|M.marinum_M -------------------------------------------------- MUL_0233|M.ulcerans_Agy99 -------------------------------------------------- MAV_1031|M.avium_104 -------------------------------------------------- Mflv_1758|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5636|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4989|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0097|M.thermoresistible__bu -------------------------------------------------- MAB_0962|M.abscessus_ATCC_1997 -------------------------------------------------- MLBr_02671|M.leprae_Br4923 LDDPHAATPWTADIITGTDLAAAVRILSALPVARSASESSVHLAQGGTTL Mb0932|M.bovis_AF2122/97 --------------------MTRSASATAGLTDAEVAQRVAEGKSNDIPE Rv0908|M.tuberculosis_H37Rv --------------------MTRSASATAGLTDAEVAQRVAEGKSNDIPE MMAR_4622|M.marinum_M --------------------MT-----AIGLTDAEVAARLAEGKSNDIPE MUL_0233|M.ulcerans_Agy99 --------------------MT-----AIGLTDVEVAARLAEGKSNDIPE MAV_1031|M.avium_104 --------------------MN------TGLTDAEVAQRVAHGQSNAVRQ Mflv_1758|M.gilvum_PYR-GCK -----------------MSAPS--DNLVAGLSDAEVAARVAEGKTNDVPT MSMEG_5636|M.smegmatis_MC2_155 --------------------MT--TMAAAGLTDAEVAQRIAEGKTNDVPT Mvan_4989|M.vanbaalenii_PYR-1 --------------------MT--VSVVTGLSEAEVAQRVAEGKTNDVPT TH_0097|M.thermoresistible__bu --------------------VT--TTLAPGLSDAEVAQRVAAGQTNDVPT MAB_0962|M.abscessus_ATCC_1997 -------------------MATIEGLTISGLTAAEVAERVAQGKTNDVPS MLBr_02671|M.leprae_Br4923 AGLLLITASAGSKSASPITLRRWFSPVNAAAATALVTGVVSASKVLRLPD . : . *: :: .: : Mb0932|M.bovis_AF2122/97 RVTRTVGQIVRAN---VFTRINAILG------------------------ Rv0908|M.tuberculosis_H37Rv RVTRTVGQIVRAN---VFTRINAILG------------------------ MMAR_4622|M.marinum_M RATRSVAQIVRAN---VFTRINAILG------------------------ MUL_0233|M.ulcerans_Agy99 RATRRVAQIVRAN---VFTRINAILG------------------------ MAV_1031|M.avium_104 RATRSITDIVRAN---VFTRINAILG------------------------ Mflv_1758|M.gilvum_PYR-GCK RAARSVSEIIRGN---VFTRINAILG------------------------ MSMEG_5636|M.smegmatis_MC2_155 RAARTVSEIVRAN---VFTRINAILG------------------------ Mvan_4989|M.vanbaalenii_PYR-1 RAARSVSEIVRGN---VFTRINAILG------------------------ TH_0097|M.thermoresistible__bu RAARTTGEIIRAN---VFTRINGILG------------------------ MAB_0962|M.abscessus_ATCC_1997 RAARSVSDIVRAN---VFTRINAILG------------------------ MLBr_02671|M.leprae_Br4923 PTPQPLTAWHALDPEIVYSRLAGVTQPLAVEPGTPDWRRRLDDLSYTRAL ..: : *::*: .: Mb0932|M.bovis_AF2122/97 --------------------------VLLLIVLATGSLINGMFGLLIIA- Rv0908|M.tuberculosis_H37Rv --------------------------VLLLIVLATGSLINGMFGLLIIA- MMAR_4622|M.marinum_M --------------------------VLLLIVLATGSVINGMFGLLIIA- MUL_0233|M.ulcerans_Agy99 --------------------------VLLLIVLATGSVINGMFGLLIIA- MAV_1031|M.avium_104 --------------------------VLLLIVLATGSVINGMFGLLIIA- Mflv_1758|M.gilvum_PYR-GCK --------------------------VLFVIVLSTGSLINGAFGLLIIA- MSMEG_5636|M.smegmatis_MC2_155 --------------------------VLFVIVLSTGSVINGAFGLLIIA- Mvan_4989|M.vanbaalenii_PYR-1 --------------------------VLLIIVLATGSVINGAFGLLIIA- TH_0097|M.thermoresistible__bu --------------------------VLFLIVLSTGSIINGAFGLLIIA- MAB_0962|M.abscessus_ATCC_1997 --------------------------VLLIIVLSTGSIINGAFGLLIIA- MLBr_02671|M.leprae_Br4923 SPLRKPVTKLARLASATRQEFADPLTPILAVGAAASAIVGSNIDALLVAG :: : ::.:::.. :. *::* Mb0932|M.bovis_AF2122/97 ----NSVIGMVQEIRAKQTLDKLAIIG---------QAKPLVRRQSGT-- Rv0908|M.tuberculosis_H37Rv ----NSVIGMVQEIRAKQTLDKLAIIG---------QAKPLVRRQSGT-- MMAR_4622|M.marinum_M ----NSIIGMIQELRAKQTLDNLAILG---------QAKPLVRRQSGT-- MUL_0233|M.ulcerans_Agy99 ----NSIIGMIQELRAKQTLDNLAILG---------QAKPLVRRQSGT-- MAV_1031|M.avium_104 ----NSVVGMVQEIRAKQTLDKLAIVG---------QAKPMVRRQSGT-- Mflv_1758|M.gilvum_PYR-GCK ----NSAIGIIQELRAKQTLDKLAIVG---------QAKPLVRRQSGT-- MSMEG_5636|M.smegmatis_MC2_155 ----NSAIGIIQEIRAKQTLDKLAIVG---------QAKPTVRRQSGT-- Mvan_4989|M.vanbaalenii_PYR-1 ----NSAIGIIQELRAKQTLDKLAIVG---------QAKPLVRRKSGTGS TH_0097|M.thermoresistible__bu ----NSAVGMIQELRAKRTLDNLAIIG---------QAKPMVRRRSGT-- MAB_0962|M.abscessus_ATCC_1997 ----NSAVGIIQELRAKQILDKLAIVG---------QTRPLVRRDGAA-- MLBr_02671|M.leprae_Br4923 VMTVNAITGGVQRLRAEAAAAELFAEQDQLVRRVVVPAVATTRRRLEAAQ *: * :*.:**: :* : . .** : Mb0932|M.bovis_AF2122/97 -----RTRSTNEVVLDDIIELGPGDQVVVDGEVVEEENLEIDESLLTGEA Rv0908|M.tuberculosis_H37Rv -----RTRSTNEVVLDDIIELGPGDQVVVDGEVVEEENLEIDESLLTGEA MMAR_4622|M.marinum_M -----RTMSPSEVVLDDVIELGPGDQVVVDGEVLEQDNLEIDESLLTGEA MUL_0233|M.ulcerans_Agy99 -----RTMSPSEVVLDDVIELGPGDQVVVDGEVLEQDNLEIDESLLTGEA MAV_1031|M.avium_104 -----HALPPDEVVLDDIIELGPGDQVVVDGEIVEEANLEVDESLLTGEA Mflv_1758|M.gilvum_PYR-GCK -----QPMPPSEVVLDDVIELGPGDQIVVDGVILEETNLEVDESLLTGEA MSMEG_5636|M.smegmatis_MC2_155 -----RAVLPSEVVLDDIIELGPGDQIVVDGEVVEETNLEVDESLLTGEA Mvan_4989|M.vanbaalenii_PYR-1 VS---LPLAPSEVVLDDVIELGPGDQIVVDGVILEESNLEIDESLLTGEA TH_0097|M.thermoresistible__bu -----RALAPSEVVLDDIIELGPGDQIVVDGEVVEAANLEIDESLLTGEA MAB_0962|M.abscessus_ATCC_1997 -----TALAPNEVVLDDIIELGPGDQIVVDGEVIEESALEIDESLLTGEA MLBr_02671|M.leprae_Br4923 HATRTVTVSAKSLRAGDVIDLAAPEVVPADARVLVAEDLEVDESLLTGES . ...: .*:*:*.. : : .*. :: **:********: Mb0932|M.bovis_AF2122/97 DPIAKDAG----DTVMSGSFVVSGAGAYR-ATKVGSEAYAAKLAAEASKF Rv0908|M.tuberculosis_H37Rv DPIAKDAG----DTVMSGSFVVSGAGAYR-ATKVGSEAYAAKLAAEASKF MMAR_4622|M.marinum_M DSIAKHVG----EQVMSGSFVVAGSGAYR-ATKVGHEAYAAKLAAEASKF MUL_0233|M.ulcerans_Agy99 DSIAKHVG----EQVMSGSFVVAGSGAYR-ATKVGHEAYAAKLAAEASKF MAV_1031|M.avium_104 DPIAKAVG----DSVMSGSFVVAGTGAYR-ATRVGSQAYAARLAEEASKF Mflv_1758|M.gilvum_PYR-GCK DAIAKDAG----DHVMSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF MSMEG_5636|M.smegmatis_MC2_155 DPIAKDAG----DPVMSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF Mvan_4989|M.vanbaalenii_PYR-1 DAIAKGID----DHVMSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF TH_0097|M.thermoresistible__bu DPIPKEPG----DQVMSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF MAB_0962|M.abscessus_ATCC_1997 DAIEKTIG----SQVLSGSFVVAGSGAYR-ATKVGREAYAAKLAEEASKF MLBr_02671|M.leprae_Br4923 LPVDKRVDPVAINDADRASMLFEGSAIVAGHARAIVVATGVGTAAHRAIS .: * . . . .*::. *:. ::. * .. * . : Mb0932|M.bovis_AF2122/97 TLVKSELRNGINRILQFITYLLVP---AGLLTIYTQLFTTHVGWRESVLR Rv0908|M.tuberculosis_H37Rv TLVKSELRNGINRILQFITYLLVP---AGLLTIYTQLFTTHVGWRESVLR MMAR_4622|M.marinum_M TLVKSELRSGINKILQFITYLLIP---AGLLTIYTQLFTTHAGWRDSVLR MUL_0233|M.ulcerans_Agy99 TLVKSELRSGINKILQFITYLLIP---AGLLTIYTQLFTTHAGWRDSVLR MAV_1031|M.avium_104 TLVKSELRNGINRILQFITYLLVP---AGLLTIYTQLFTTHAGWQKSVLR Mflv_1758|M.gilvum_PYR-GCK TLVRSELRNGINQILRFITYLLIP---AGALIIYTQLFTTDSGWRESVLR MSMEG_5636|M.smegmatis_MC2_155 TLVKSELRNGINKILQFITYLLVP---AGLLTIYTQLFTTDAGWREAVLR Mvan_4989|M.vanbaalenii_PYR-1 TLVKSELRNGINKILQFITYLLVP---AGALTIYTQLFTTDAGWRRAVLA TH_0097|M.thermoresistible__bu TLVKSDLRNGINTILRFITYLLIP---AGLLTIYTQLFTTDADWRRAVLA MAB_0962|M.abscessus_ATCC_1997 TLVHSELRNGINKILQFITYLLLP---AGALIIYTQLFTTDDSWQESVLR MLBr_02671|M.leprae_Br4923 AVADVEVSAGVQARLRELTSKVLPLTLAGGAAVTGLALLRRASLRQAVAD ::. :: *:: *: :* ::* ** : : . : :* Mb0932|M.bovis_AF2122/97 MVGALVPMVPEGLVLMTSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVV Rv0908|M.tuberculosis_H37Rv MVGALVPMVPEGLVLMTSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVV MMAR_4622|M.marinum_M TVGALVPMVPEGLVLMTSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVV MUL_0233|M.ulcerans_Agy99 TVGALVPMVPEGLVLITSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVV MAV_1031|M.avium_104 TVGALVPMVPEGLVLLTSVAFAVGVVRLGQRRCLVQELPAIEGLARVDVV Mflv_1758|M.gilvum_PYR-GCK MVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVNELPAIEGLARVDVV MSMEG_5636|M.smegmatis_MC2_155 MVGALVPMVPEGLVLMTSIAFAVGVVRLGRRQCLVNELPAIEGLARVDVV Mvan_4989|M.vanbaalenii_PYR-1 MVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVNELPAIEGLARVDVV TH_0097|M.thermoresistible__bu MVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVNELPAIEGLARVDVV MAB_0962|M.abscessus_ATCC_1997 MVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVQELPAIEGLARVDTV MLBr_02671|M.leprae_Br4923 GVAIAVAAVPEGLPLVATLSQLAAAQRLTAKGALVRSPRTIEALGRVDTI *. *. ***** *::::: ... ** : .**.. :**.*.***.: Mb0932|M.bovis_AF2122/97 CADKTGTLTESGMRVCEVEELDG--------AGRQESVADVLAALAAADA Rv0908|M.tuberculosis_H37Rv CADKTGTLTESGMRVCEVEELDG--------AGRQESVADVLAALAAADA MMAR_4622|M.marinum_M CADKTGTLTETGMRVSDVDELI---------ADQHGAVADVLAFLAAADA MUL_0233|M.ulcerans_Agy99 CADKTGTLTETGMRVSDVDELI---------ADQHGAVADVLAFLAAADA MAV_1031|M.avium_104 CADKTGTLTESGMRVARVDELD---------GSGHDRIADVLAALAAADP Mflv_1758|M.gilvum_PYR-GCK CADKTGTLTENGMRVSDLKVLES------------RSVTDVLAQLAADDA MSMEG_5636|M.smegmatis_MC2_155 CADKTGTLTENGMRVSDLKSLTE------------GHVADVLAQLASDDA Mvan_4989|M.vanbaalenii_PYR-1 CADKTGTLTENGMRVSEVKRIDARPTGEERSDRGMGTVADVLAQLAADDP TH_0097|M.thermoresistible__bu CADKTGTLTENGMRVAELRHLTE--------SGDRSRVEAVLASLAADDP MAB_0962|M.abscessus_ATCC_1997 CADKTGTLTENGMRLADVHFPDR---------DGDEDALAVLAQLAADDP MLBr_02671|M.leprae_Br4923 CFDKTGTLTENRLRVVCAVPNTR-MPHDPLPDITDPHSAAVLRDAARAST * ********. :*: ** * .. Mb0932|M.bovis_AF2122/97 RPNAS------------MQAIAEAFHSPPGWVVAANAPFKSATKWSGVSF Rv0908|M.tuberculosis_H37Rv RPNAS------------MQAIAEAFHSPPGWVVAANAPFKSATKWSGVSF MMAR_4622|M.marinum_M RPNAS------------MQAIAQAFPSPPDWTPTATAPFKSATKWSGISF MUL_0233|M.ulcerans_Agy99 RPNAS------------MQAIAQAFPSPPDWTSTATAPFKSATKWSGISF MAV_1031|M.avium_104 RPNAS------------MRAIAQTYSRPPGWTVTATAPFKSATKWSGVSF Mflv_1758|M.gilvum_PYR-GCK RPNAS------------MAAIAEAYAVPPGWTATATAPFKSATKWSGASY MSMEG_5636|M.smegmatis_MC2_155 RPNAS------------MAAIAEAYQTPPGWSATATAPFKSATKWSGTSY Mvan_4989|M.vanbaalenii_PYR-1 RPNAS------------MAAIAEAYKMPPGWTATATAPFKSATKWSGTSY TH_0097|M.thermoresistible__bu RPNAS------------MQAIAEAYPDPPGWAATAIAPFKSALKWSGVSY MAB_0962|M.abscessus_ATCC_1997 RPNAS------------IAAIAEAYDTPPGWETTAIAPFSSAKKWSGASY MLBr_02671|M.leprae_Br4923 QPHDGQGHTHATDEAILTAASSLNSHTDSTWSLIAEVPFESSRGYAAAIG :*: . * : . * * .**.*: ::. Mb0932|M.bovis_AF2122/97 RDHGN-----WVIGAPDVLLDPASVAARQAERIGAQ---------GLRVL Rv0908|M.tuberculosis_H37Rv RDHGN-----WVIGAPDVLLDPASVAARQAERIGAQ---------GLRVL MMAR_4622|M.marinum_M RDHGN-----WVIGAPDVLLDSASDAAREAERIGAQ---------GLRIL MUL_0233|M.ulcerans_Agy99 RDHGN-----WVIGAPDVLLDSASEAAREAERIGAQ---------GLRIL MAV_1031|M.avium_104 AGHGD-----WVMGAPDVLLDSCSAAAGQAERLGAQ---------GLRVL Mflv_1758|M.gilvum_PYR-GCK AEHGN-----WVIGAPDVLLDPASPVAEDAERIGAR---------GLRVL MSMEG_5636|M.smegmatis_MC2_155 GEHGN-----WVIGAPDVLLDPASPVAEEAERIGAQ---------GLRVL Mvan_4989|M.vanbaalenii_PYR-1 GDHGN-----WVIGAPDVLLDPTSTAAEEAERIGAQ---------GLRVL TH_0097|M.thermoresistible__bu GEHGN-----WVIGAPDVLLDPASPAARQAEEIGSR---------GLRVL MAB_0962|M.abscessus_ATCC_1997 GEHGN-----WVIGAPDVLLDPADAIATAAEEIGAR---------GLRVL MLBr_02671|M.leprae_Br4923 ITGNGKAPMLMLKGAPEKILPRCRFADPEADVAHAESLVRHLAEQGLRVL .. : ***: :* *: :. ***:* Mb0932|M.bovis_AF2122/97 LLAAGSVAVDHA-----------QAPGQVTPVALVVLEQKVRPDARETLD Rv0908|M.tuberculosis_H37Rv LLAAGSVAVDHA-----------QAPGQVTPVALVVLEQKVRPDARETLD MMAR_4622|M.marinum_M LLGVADVAVDDP-----------CAPGQVTPAALVILEQKVRPDARETME MUL_0233|M.ulcerans_Agy99 LLGVAAVAVDDP-----------CAPGQVTPAALVILEQKVRPDARETME MAV_1031|M.avium_104 LLGAADRAVDHP-----------DAPGPITPVALVVLEQKVRPDARETLD Mflv_1758|M.gilvum_PYR-GCK LLGSSDRPVDAP-----------DAPGVVTPAALVVLEQRVRPDARGTLD MSMEG_5636|M.smegmatis_MC2_155 LLGSSDRSVDAP-----------DAPGVVTPAALVVLEQRIRPDAGDTLD Mvan_4989|M.vanbaalenii_PYR-1 LLGSSDRSVDAP-----------DAPGTVTPSALVVLEQRIRPDARDTLD TH_0097|M.thermoresistible__bu LLGSSDLPVDHP-----------QAPGAVTPVALVVLEQRIRSDARDTLE MAB_0962|M.abscessus_ATCC_1997 LLASAELSVDDA-----------HAPGAVTPRALVVLEQKIRPDARETLD MLBr_02671|M.leprae_Br4923 AVAQCSWGHDTTDDNDTDADAVDAAAHDLELVGYIGLADTARPSSRPLIE :. * . *. : . : * : *..: :: Mb0932|M.bovis_AF2122/97 YFAVQNVSVKVISGDNAVSVGAVADRLGLHGEAMDAR---ALPTGREELA Rv0908|M.tuberculosis_H37Rv YFAVQNVSVKVISGDNAVSVGAVADRLGLHGEAMDAR---ALPTGREELA MMAR_4622|M.marinum_M YFAAQNVSVKVISGDNAVSVGAVAAKLGLQVQTMDAR---QLPSEQPELA MUL_0233|M.ulcerans_Agy99 YFAAQNVSVKVISGDNAVSVGAVAAKLGLQGQTMDAR---QLPSEQPELA MAV_1031|M.avium_104 YFADQGVSVKVLSGDNAVSVGAVAGELGLHGETLDAR---QLPSDLAQLA Mflv_1758|M.gilvum_PYR-GCK YFASQHVAIKVISGDNAVSVGAVAGSLGLQGETMDAR---RLPEQQDELA MSMEG_5636|M.smegmatis_MC2_155 YFASQHVSVKVISGDNAVSVGAVAGKLGLHGETMDAR---RLPEQPEKLA Mvan_4989|M.vanbaalenii_PYR-1 YFASQKVSVKVISGDNAVSVGAVAGSLGLGGETMDAR---RLPDQPDALA TH_0097|M.thermoresistible__bu YFASQQVSIKVISGDNAASVGAVSESLGLEGEAIDAR---RLPEDPDELA MAB_0962|M.abscessus_ATCC_1997 YFASQHVSIKVISGDNAVSVSAVAQTLGLTGAAVDAR---TLPTDTDKLA MLBr_02671|M.leprae_Br4923 ALVTAGRNVVLITGDHPITARAIAQQLGLRSDARVVNGTELIGLDEDACA :. : :::**:. :. *:: *** : .. : * Mb0932|M.bovis_AF2122/97 DTLDSYTSFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG Rv0908|M.tuberculosis_H37Rv DTLDSYTSFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG MMAR_4622|M.marinum_M DVLDTYTTFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG MUL_0233|M.ulcerans_Agy99 DVLDTYITFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG MAV_1031|M.avium_104 DMLDTYTTFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIG Mflv_1758|M.gilvum_PYR-GCK ETLEECTTFGRVRPDQKRAMVHALQSRGHTVAMTGDGVNDVLALKDADIG MSMEG_5636|M.smegmatis_MC2_155 ETLEECTTFGRVRPDQKRAMVHALQSRGHTVAMTGDGVNDVLALKDSDIG Mvan_4989|M.vanbaalenii_PYR-1 DTLEQCTTFGRVRPDQKRAMVHALQSRGHTVAMTGDGVNDVLALKDADIG TH_0097|M.thermoresistible__bu DTLQRYTTFGRVRPDQKRSMVHALQSRGHTVAMTGDGVNDVLALKDADIG MAB_0962|M.abscessus_ATCC_1997 ATLADATTFGRVRPDQKRAMVKALQSHGHTVAMTGDGVNDVLALKDADIG MLBr_02671|M.leprae_Br4923 ELAADVQVFARVSPEQKVQIVAALQRCGQVTAMVGDGANDAAAIRMADVG *.** *:** :* *** *:..**.***.**. *:: :*:* Mb0932|M.bovis_AF2122/97 VAMGS-GSPASRAVAQIVLLNNRFATLPHVVGEGRRVIGNIERVANLFLT Rv0908|M.tuberculosis_H37Rv VAMGS-GSPASRAVAQIVLLNNRFATLPHVVGEGRRVIGNIERVANLFLT MMAR_4622|M.marinum_M VAMGT-GSPASRAVAQIVLLDNRFATLPYVVGEGRRVIGNIERVANLFLT MUL_0233|M.ulcerans_Agy99 VAMGT-GSPASRAVAQIVLLDNRFATLPYVVGEGRRVIRNIERVANLFLT MAV_1031|M.avium_104 VAMGA-GSPASRAVAQIVLLDNRFATLPYVVGEGRRVIGNIERVANLFLT Mflv_1758|M.gilvum_PYR-GCK VAMGS-GSSASRAVAQIVLLDNKFATLPYVVGEGRRVIGNIERVSNLFLT MSMEG_5636|M.smegmatis_MC2_155 VAMGS-GSSASRAVAQIVLLDNKFATLPYVVGEGRRVIGNIERVSNLFLT Mvan_4989|M.vanbaalenii_PYR-1 VAMGS-GSSASRAVAQIVLLDNKFATLPYVVGEGRRVIGNIERVSNLFLT TH_0097|M.thermoresistible__bu VAMGS-GSPATRAVAQIVLLDNKFATLPHVVAEGRRVIGNIERVSNLFLT MAB_0962|M.abscessus_ATCC_1997 VAMGA-GSSASRAVAQIVLLDNKFATLPYVVAEGRRVIGNIERVSNLFLT MLBr_02671|M.leprae_Br4923 IGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMWAGVRDAVTILVG :.:. **.*:*..*:*** :: :..* .: *** : .:. . .::: Mb0932|M.bovis_AF2122/97 KTVYSVLLALLVGIECLIAIPLRRDPLLFP------FQPIHVTIAAWFT- Rv0908|M.tuberculosis_H37Rv KTVYSVLLALLVGIECLIAIPLRRDPLLFP------FQPIHVTIAAWFT- MMAR_4622|M.marinum_M KTVYSALLALLVGIECLFAKPLGADPLLYP------FQPIHVTIAAWFT- MUL_0233|M.ulcerans_Agy99 KAVYSALLALLVGIECLFAKPLGADPLLYP------FQPIHVTIAAWFT- MAV_1031|M.avium_104 KTVYSVLLALLVGLECLFAKALKADPLLYP------FQPIHVTVAAWFT- Mflv_1758|M.gilvum_PYR-GCK KTVYSVLLAVLVGLAGLSAEIFDTDPLLFP------FQPIHVTIAAWFT- MSMEG_5636|M.smegmatis_MC2_155 KTVYSVLLAILVGIGGLSAKIFGTDPLLFP------FQPIHVTIAAWFT- Mvan_4989|M.vanbaalenii_PYR-1 KTVYSVLLAVLVGLGGLSAKLFGSDPLLFP------FQPIHVTIAAWFT- TH_0097|M.thermoresistible__bu KTVYSVLLAVLVGLGGLASVFFEADPLLFP------FQPIHVTIAAWFT- MAB_0962|M.abscessus_ATCC_1997 KTVYSVLLALTVGLAGLGSKIFHYGAVPFP------FQPIHVTIAAWFT- MLBr_02671|M.leprae_Br4923 GNVGEVVFTIIGTVFGAGRAPVGTRQLLLVNLLTDMFPALSIAVTSQYEE * ..:::: : . : * .: ::::: : Mb0932|M.bovis_AF2122/97 IGIPAFILSLAPNNER------AYPGFVRRVMTSAVPFGLVIGVATFVTY Rv0908|M.tuberculosis_H37Rv IGIPAFILSLAPNNER------AYPGFVRRVMTSAVPFGLVIGVATFVTY MMAR_4622|M.marinum_M IGIPSFILSLAPNDER------AYPGFVRRVLTSALPSGLVVGVATFVSY MUL_0233|M.ulcerans_Agy99 IGIPSFILSLAPNDER------AYPGFVRRVLTSALPSGLVVGVATFVSY MAV_1031|M.avium_104 IGIPSFILSLAPNNER------AHPGFVRRVLSSALPSGLIVGAATFASY Mflv_1758|M.gilvum_PYR-GCK IGIPAFVLSLAPNNER------AHPGFVRRVMTAALPSGVVVGIATFTSY MSMEG_5636|M.smegmatis_MC2_155 IGIPAFILSLAPNNER------AKTGFVRRVMTAALPSGLVVGTATFVSY Mvan_4989|M.vanbaalenii_PYR-1 IGIPAFVLSLAPNNER------AHPGFVRRVMTSALPSGIVVGAATFTSY TH_0097|M.thermoresistible__bu IGIPAFILSLAPNTER------AKPHFVRRVMTSALPSGITIGIATFTSY MAB_0962|M.abscessus_ATCC_1997 IGIPAFILSLAPNNER------AQTGFVRRVMLSAIPSGLTVGIATFLSY MLBr_02671|M.leprae_Br4923 PGEDEYQTDEEADEARRTHQHEVLTGPTPSLDAPLMRQIVNRGVVTAAGA * : . .: * . . . : . : : * .* Mb0932|M.bovis_AF2122/97 LAAYQGRYASWQEQEQASTAALITLLMTALWVLAVIARPYQWWRLALVLA Rv0908|M.tuberculosis_H37Rv LAAYQGRYASWQEQEQASTAALITLLMTALWVLAVIARPYQWWRLALVLA MMAR_4622|M.marinum_M LTAYPGRHSTWQEQTQASTAALITLLVTALWVLAVVARPYRWWRLGLVIA MUL_0233|M.ulcerans_Agy99 LTAYPGRHSTWQEQTQASTAALITLLVTALWVLAVVARPYRWWRLGLVIA MAV_1031|M.avium_104 LVAYHGRHATFQQQDQASTAALITLLVTALWVLAVVARPYQWWRVALVIA Mflv_1758|M.gilvum_PYR-GCK LLAYQGRAATETEQTQASTAALITLLVAALWVLAVVARPYEWWRVALVSI MSMEG_5636|M.smegmatis_MC2_155 LVAYQGREATPVEQTQASTAALITLLASSLWVLAVVARPYQWWRVLLVAC Mvan_4989|M.vanbaalenii_PYR-1 LLAYQGRAATEAEQTQASTAALITLLVAGVWVLSVVARPYEWWRVALVAV TH_0097|M.thermoresistible__bu LIAYQGREATAVQQTQASTAALITLLVAALWVLAVVARPYQWWRVALVLV MAB_0962|M.abscessus_ATCC_1997 LLARQILHVSG-NSTQASTAALITELVAAVWVLAVVARPYQWWRVALVAL MLBr_02671|M.leprae_Br4923 TTAWAIGRWTPGTERRTATMG-LTALVTTQLAQTLLTRRHSPLVVATALG * : . :::* . :* * : . ::::* : : . Mb0932|M.bovis_AF2122/97 SGLAYVVIFSLPLAREKFLLDAS-NLATTSIALAVGVVGAATIEAMWWIR Rv0908|M.tuberculosis_H37Rv SGLAYVVIFSLPLAREKFLLDAS-NLATTSIALAVGVVGAATIEAMWWIR MMAR_4622|M.marinum_M CGLAYVAIFSLPLAQRKFFLDPS-NLATTSIALGIGLLGAALIEAMWWLR MUL_0233|M.ulcerans_Agy99 CGLAYVAIFSLPLAQRKFFLDPS-NLATTSIALGIGVLGAALIEAMWWLR MAV_1031|M.avium_104 SGLAYVVIFSLPLARKAFLLDPS-NVVVTLSALGIGVLGAAAIEAAWWIR Mflv_1758|M.gilvum_PYR-GCK SALAYVVIFSIPAARELFILDPT-NMTTTSTALAIGIAAAAAIEVLWWVQ MSMEG_5636|M.smegmatis_MC2_155 SMLAYVLIFSIPLAQELFMLDPT-NMKVTSVALGIGLAGAALIEVLWWVQ Mvan_4989|M.vanbaalenii_PYR-1 SGLAYVVIFSIPLARELFILDPS-NTALTSMALGIGLAAAVAIEVIWWVQ TH_0097|M.thermoresistible__bu SMLAYVVIFAIPLARDVFMLDPS-NVAVTATAFGIGVIAAAVIEAAWWVQ MAB_0962|M.abscessus_ATCC_1997 SGLGYVAIFAIPLARKAFMLDPG-NLAVTGPALGIGIAAAAVIEAVWWLQ MLBr_02671|M.leprae_Br4923 SAGVLIGIIQTPVISQFFGCTPLGPIAWSGVITATAGATAVSVLAPQWLN . : *: * * . : . . *. : . *:. Mb0932|M.bovis_AF2122/97 SRMLGVKPRVWR---- Rv0908|M.tuberculosis_H37Rv SRMLGVKPRVWR---- MMAR_4622|M.marinum_M ARALGLRPRVWR---- MUL_0233|M.ulcerans_Agy99 ARALGLRPRVWR---- MAV_1031|M.avium_104 AKMLGVRPRVWR---- Mflv_1758|M.gilvum_PYR-GCK GHVLGERRRLWRAADG MSMEG_5636|M.smegmatis_MC2_155 GRVLGEERRVWR---- Mvan_4989|M.vanbaalenii_PYR-1 GRVLGEHRRLWRVRER TH_0097|M.thermoresistible__bu GRMLGETRRLWK---- MAB_0962|M.abscessus_ATCC_1997 GKWSGQPRHFWATGDD MLBr_02671|M.leprae_Br4923 -KAFGIAQLNQE---- : *