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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2512 | - | - | 100% (274) | 6-phosphogluconate dehydrogenase, NAD-binding |
| M. thermoresistible (build 8) | TH_1259 | - | 3e-37 | 36.82% (220) | putative oxidoreductase |
| M. thermoresistible (build 8) | TH_0328 | mmsB | 8e-23 | 30.31% (254) | PROBABLE 3-HYDROXYISOBUTYRATE DEHYDROGENASE MMSB (HIBADH) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0793 | - | 8e-34 | 33.19% (229) | dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_2481 | - | 1e-129 | 83.09% (272) | 6-phosphogluconate dehydrogenase, NAD-binding |
| M. tuberculosis H37Rv | Rv0770 | - | 1e-34 | 33.62% (229) | dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_02065 | gnd | 6e-05 | 24.22% (223) | 6-phosphogluconate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1220 | - | 2e-30 | 34.63% (231) | dehydrogenase/reductase |
| M. marinum M | MMAR_4926 | - | 3e-33 | 33.47% (245) | dehydrogenase/reductase |
| M. avium 104 | MAV_0917 | - | 4e-96 | 63.97% (272) | 6-phosphogluconate dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4816 | - | 1e-111 | 72.43% (272) | 6-phosphogluconate dehydrogenase, NAD-binding |
| M. ulcerans Agy99 | MUL_0835 | mmsB | 8e-21 | 27.24% (257) | 3-hydroxyisobutyrate dehydrogenase, MmsB |
| M. vanbaalenii PYR-1 | Mvan_4173 | - | 1e-129 | 83.82% (272) | 6-phosphogluconate dehydrogenase, NAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0793|M.bovis_AF2122/97 ---MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFV
Rv0770|M.tuberculosis_H37Rv ---MTAHPETPRLGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFV
MMAR_4926|M.marinum_M ---MSEH---PKLGYIGLGNQGAPMAKRLLDWPGGLVVYDVRAEAMTPLA
MAB_1220|M.abscessus_ATCC_1997 ---MTQQ--AMKLGYIGLGNMGAPMARRLVDWPGGLTVFDLRAEAVAPLV
Mflv_2481|M.gilvum_PYR-GCK ----------MRVGFIGLGSQGGPMARRIAEGGFETTLWARRQASLEPYS
Mvan_4173|M.vanbaalenii_PYR-1 ----------MRVGFIGLGSQGGPMARRIAEGGFETTLWARRPASLEPYA
TH_2512|M.thermoresistible__bu ----------MRVGFIGLGSQGGPMARRIAENGYETTLWARRAATLEPFA
MSMEG_4816|M.smegmatis_MC2_155 ----------MRVGFIGLGSQGAPMARRIVEGGFETTLWARRPASLEPFA
MAV_0917|M.avium_104 ----------MRVGFIGLGSQGGPMARRIVEGGYPTTLWARRPATLEVFA
MUL_0835|M.ulcerans_Agy99 ------MTKSCQIAFLGLGHMGAPMSANLIGAGHTVRGFDPVPAAASATA
MLBr_02065|M.leprae_Br4923 MSAPESKTAIAQIGVTGLAVMGSNIARNFARHGYTVALHNRSIAKTDTLL
::. **. *. :: .:
Mb0793|M.bovis_AF2122/97 EGGAT-----AAASVSDVAEA-DIISITVFDDAQVSSVITADNGLATHAK
Rv0770|M.tuberculosis_H37Rv EGGAT-----AAASVSDVAEA-DIISITVFDDAQVSSVITADNGLATHAK
MMAR_4926|M.marinum_M EAGAS-----AAASVAEVAGA-DIISVTVLNDAQVREVITGANGLAAHAR
MAB_1220|M.abscessus_ATCC_1997 EEGAV-----GASDVADIADA-DLISVTVLDDAQVRQVVG---QVAPKAK
Mflv_2481|M.gilvum_PYR-GCK DTPAK-----TASTPAELGAASDLVCLCVVGDDDVREVLYGEQGVLAGLA
Mvan_4173|M.vanbaalenii_PYR-1 DTPAK-----TAATPAELGANSDLVCLCVVGDDDVREVLYGESGVLAGLA
TH_2512|M.thermoresistible__bu DTPAK-----TAGSPAELGAASDLVCLCVVGDDDVREVLYGDTGVLAGLA
MSMEG_4816|M.smegmatis_MC2_155 DTAAK-----VAGTPAELAAASDLVCLCVVGDDDVREVLDGETGVLAGLA
MAV_0917|M.avium_104 DTDAK-----VAGSPAELAAASDLVCLCVIGDADIDELTDGEHGLLSAMQ
MUL_0835|M.ulcerans_Agy99 AKGAT-----MFDSAAEAVARADVVITMLPNGAVVKRCYA---EVLPAAR
MLBr_02065|M.leprae_Br4923 KEHGSEGNFVRTETIPEFLAALQTPRRVLIMVKAGDATDAVINELADVME
. .: : : :
Mb0793|M.bovis_AF2122/97 PGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPGSGGAAAAAKGELAVM
Rv0770|M.tuberculosis_H37Rv PGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSGGAAAAAKGELAVM
MMAR_4926|M.marinum_M AGTIIAIHSTISDTTAEELARELRPRGIHVIDAPVSGGAGAASKGQLATM
MAB_1220|M.abscessus_ATCC_1997 PGTIIAIHSTISDTTAVELAQAWRPRDIHVIDAPVSGGAPGAHKGELATM
Mflv_2481|M.gilvum_PYR-GCK EGGIIAIHSTVHPQTCQEIAEKGAAQGVSVIDAPVSGGGPAVEQGTLLVM
Mvan_4173|M.vanbaalenii_PYR-1 EGGIIAIHSTVHPDTCREIAEKSAAQGISVIDAPVSGGGPAVEQGTLLVM
TH_2512|M.thermoresistible__bu PGGVVAIHSTVHPDTCREISEKAAAQQVSVIDAPVSGGGPAVEEGKLLVM
MSMEG_4816|M.smegmatis_MC2_155 PGGIIAIHSTVHPDTCTEIAEQVAEKGISLIDAPVSGGEPAAKAGTLLVM
MAV_0917|M.avium_104 PGGVIAVHSTVHPDTCRKLAKRAAALGVSVVDAPVSGGGGAAAEGRLLVM
MUL_0835|M.ulcerans_Agy99 SGALFIDSSTISVNDAREVHALAESHGMAQLDAPVSGGVKGAVAGTLAFM
MLBr_02065|M.leprae_Br4923 PSDIIIDGGNSLFTDTIRREKAMRERGLHFVGAGISGGEEGALNG-PSIM
. :. .. : :.* *** .. * *
Mb0793|M.bovis_AF2122/97 VGADDEAFQRIKEPFSRWASLLI------HAGEPGAGTRMKLARNMLTFV
Rv0770|M.tuberculosis_H37Rv VGADDEAFQRIKEPFSRWASLLI------HAGEPGAGTRMKLARNMLTFV
MMAR_4926|M.marinum_M VGAGDDVFARVKEPFSCWASLVV------HAGPPGAGTRMKLARNMLTFT
MAB_1220|M.abscessus_ATCC_1997 VGADGETFARVKEAFSKWASLVI------HAGAPGAGTRMKLARNLLHFV
Mflv_2481|M.gilvum_PYR-GCK VGGDEEVAERCRPVFATYADPIV------HLGPLGSGQNTKILNNLLFSA
Mvan_4173|M.vanbaalenii_PYR-1 VGGDEEVAQRCRPVFATYADPIV------HLGPLGSGQNTKILNNLLFSA
TH_2512|M.thermoresistible__bu VGGDEEVVERCRPVFASYADPIV------HLGPLGSGQVTKILNNLLFTA
MSMEG_4816|M.smegmatis_MC2_155 AGGDEDIVDKVRPVFATYADPVV------RLGGVGSGQVAKILNNLLFSA
MAV_0917|M.avium_104 AGGDADVVERCRPVFETYADPVV------HLGELGSGQTTKLLNNLLFTA
MUL_0835|M.ulcerans_Agy99 VGGDQSALAQARPVLEPMAGKII------HCGAAGAGQAAKVCNNMVLAV
MLBr_02065|M.leprae_Br4923 PGGPAESYTSLGPLLEEISAHVDGVSCCTHIGPGGSGHFVKMVHNGIEYS
*. . : : : : * *:* *: .* :
Mb0793|M.bovis_AF2122/97 SYAAAAEAQRLA-EACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPME
Rv0770|M.tuberculosis_H37Rv SYAAAAEAQRLA-EACGLDLVALGKVVRHSDSFTGGAGAIMFRNTTAPME
MMAR_4926|M.marinum_M IYAAVGEAWKLA-EASGVNLQDLGNVVRHTDKLTSGAGSIMFRDNTKDLE
MAB_1220|M.abscessus_ATCC_1997 AFTAAGEAQRLA-ESCGLDITDLGKVVRHTDAITGGPGAIMLRDTTEPVT
Mflv_2481|M.gilvum_PYR-GCK NLGSAVSTLELG-ESLGIPRAKLVEVLSKGSATSKAVSSISMFGGTLDGL
Mvan_4173|M.vanbaalenii_PYR-1 NLGAAVSTLELG-ESLGIPRQKLVEVLNRGSATSKAVASISMFGGTLEGL
TH_2512|M.thermoresistible__bu NLGSALSTLELG-ESLGIPRVKLAEVLNGGSATSKALGSISVFGGTVEGL
MSMEG_4816|M.smegmatis_MC2_155 NLGAAMSALELG-EALGVPRSALCEVITRGSANSKALGSIAMFGGTLDNL
MAV_0917|M.avium_104 NLATAATALSLA-EQLGVRPERLTEVVSRSSGNSFALNALGGIGG-LDQL
MUL_0835|M.ulcerans_Agy99 QQIAIGEAFVLA-ENLGLDAQSLFDVITGATGNCWAVHTNCPVPGPVPTS
MLBr_02065|M.leprae_Br4923 DMQLIGEAYQLLRDGLGMSAPQIADVFTEWNRGDLNSYLVEITAEVLRQT
: * : *: : .*.
Mb0793|M.bovis_AF2122/97 PADPLRPLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGV
Rv0770|M.tuberculosis_H37Rv PADPLRPLLEHTRGLGEKDLSLALALGEVVSVDLPLAQLALQRLAAGLGV
MMAR_4926|M.marinum_M PGHFLYDGFVHARDLGEKDLGLALALGEALSVDLPLARLALERLAPGLGV
MAB_1220|M.abscessus_ATCC_1997 PDSFWLPIFTHVRGLGEKDLSLALALGEEQSVDLPLATLAREQLAASLGV
Mflv_2481|M.gilvum_PYR-GCK AP--------IAGGLLQKDVRHAASLAAAAKAPEGAVFTAADAALEAMDH
Mvan_4173|M.vanbaalenii_PYR-1 AP--------IAGALLQKDVRHAASLAASAEAAEGAVFTAADAALEAMDH
TH_2512|M.thermoresistible__bu AP--------IAGALLQKDVRHAANIAASASVPEGTVFTVADTALTAMGH
MSMEG_4816|M.smegmatis_MC2_155 AP--------IAGALLQKDCRHAASLADAASASQGAVFGAADEALRLMNV
MAV_0917|M.avium_104 AG--------VAGALLRKDVRLVVDLAEQAGAAGGAVLDAADAALALMGH
MUL_0835|M.ulcerans_Agy99 PANNDFKPG-FATALMNKDLGLAMDAVTSTASAAPLGSHAAEIYAKFATD
MLBr_02065|M.leprae_Br4923 DIKTGRPLVDVILDKAEQKGTGRWTVQSALDLGVPITGIAEAVFARALSG
.:. .
Mb0793|M.bovis_AF2122/97 PHPDTEPAKET---------------------------------------
Rv0770|M.tuberculosis_H37Rv PHPDTEPAKET---------------------------------------
MMAR_4926|M.marinum_M PHTQKDA-------------------------------------------
MAB_1220|M.abscessus_ATCC_1997 PHEEGASNG-----------------------------------------
Mflv_2481|M.gilvum_PYR-GCK RR------------------------------------------------
Mvan_4173|M.vanbaalenii_PYR-1 RR------------------------------------------------
TH_2512|M.thermoresistible__bu ARR-----------------------------------------------
MSMEG_4816|M.smegmatis_MC2_155 PR------------------------------------------------
MAV_0917|M.avium_104 PR------------------------------------------------
MUL_0835|M.ulcerans_Agy99 HADQDFSAVIEMLRGS----------------------------------
MLBr_02065|M.leprae_Br4923 SVLQRKAAIGLASGKLGNKPTDRETFIEDVRQALYASKIVAYAQGFNHIQ
Mb0793|M.bovis_AF2122/97 --------------------------------------------------
Rv0770|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4926|M.marinum_M --------------------------------------------------
MAB_1220|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2481|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4173|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2512|M.thermoresistible__bu --------------------------------------------------
MSMEG_4816|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0917|M.avium_104 --------------------------------------------------
MUL_0835|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02065|M.leprae_Br4923 TGSTEFGWNITPGDLATIWRGGCIIRAKFLNRIKEAFDAAPDLASLIVAP
Mb0793|M.bovis_AF2122/97 --------------------------------------------------
Rv0770|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4926|M.marinum_M --------------------------------------------------
MAB_1220|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2481|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4173|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2512|M.thermoresistible__bu --------------------------------------------------
MSMEG_4816|M.smegmatis_MC2_155 --------------------------------------------------
MAV_0917|M.avium_104 --------------------------------------------------
MUL_0835|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02065|M.leprae_Br4923 YFRSAVESAIDSWRRVVSTATQLGIPNPGFSSALSYYDALRTERLPAALT
Mb0793|M.bovis_AF2122/97 ----------------------------------
Rv0770|M.tuberculosis_H37Rv ----------------------------------
MMAR_4926|M.marinum_M ----------------------------------
MAB_1220|M.abscessus_ATCC_1997 ----------------------------------
Mflv_2481|M.gilvum_PYR-GCK ----------------------------------
Mvan_4173|M.vanbaalenii_PYR-1 ----------------------------------
TH_2512|M.thermoresistible__bu ----------------------------------
MSMEG_4816|M.smegmatis_MC2_155 ----------------------------------
MAV_0917|M.avium_104 ----------------------------------
MUL_0835|M.ulcerans_Agy99 ----------------------------------
MLBr_02065|M.leprae_Br4923 QAQRDFFGAHSYGRVDARGKFHTLWSEDRSEVTV