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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2476 | - | - | 100% (539) | putative AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_2434 | - | 2e-51 | 30.32% (531) | PUTATIVE very-long-chain acyl-CoA synthetase |
| M. thermoresistible (build 8) | TH_2591 | - | 2e-49 | 31.01% (503) | PUTATIVE feruloyl-CoA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1238 | fadD6 | 3e-50 | 30.40% (523) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_2185 | - | 7e-54 | 31.29% (521) | acyl-CoA synthetase |
| M. tuberculosis H37Rv | Rv1206 | fadD6 | 3e-50 | 30.40% (523) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 4e-36 | 27.14% (490) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_3628c | - | 1e-47 | 29.59% (517) | acyl-CoA synthetase |
| M. marinum M | MMAR_4232 | fadD6 | 1e-55 | 30.65% (535) | fatty-acid-CoA ligase FadD6 |
| M. avium 104 | MAV_1639 | - | 1e-70 | 35.17% (489) | AMP-binding enzyme, putative |
| M. smegmatis MC2 155 | MSMEG_5086 | - | 2e-50 | 30.13% (531) | acyl-CoA synthetase |
| M. ulcerans Agy99 | MUL_0957 | fadD6 | 8e-56 | 30.09% (535) | acyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_0898 | - | 1e-90 | 37.88% (520) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1639|M.avium_104 -----------------------------------MRAPADFGVDRFTVP
Mvan_0898|M.vanbaalenii_PYR-1 -------------------------------------MKDNTIKTETTVV
TH_2476|M.thermoresistible__bu -----------------------------------MHWIEDSSRENVAAG
Mb1238|M.bovis_AF2122/97 MSDYYGGAHTTVRLIDLATRMPRVLADTPVIVRGAMTGLLARPNSKASIG
Rv1206|M.tuberculosis_H37Rv MSDYYGGAHTTVRLIDLATRMPRVLADTPVIVRGAMTGLLARPNSKASIG
MMAR_4232|M.marinum_M MSDRQSHVRTRVKLTDVAARVPGLLIDAPSIMRGAVTGLLPRPKSKASIG
MUL_0957|M.ulcerans_Agy99 MSDRQSHVRTRVKLTDVAARVPGLLIDAPSIMRGAVTGLLPRPKSKASIG
Mflv_2185|M.gilvum_PYR-GCK MSN-KSGTRSSVGLLDIAKQVPGLVKDTPTMLRGVVTGFGARPSAKTSIG
MSMEG_5086|M.smegmatis_MC2_155 MTD-QKATRNSVGLLDLATRLPGFLMDAPVILRGVATGFTARPSAKTSIG
MAB_3628c|M.abscessus_ATCC_199 ---------------------------------MTAVSVPRAGVPRVDIA
MLBr_02546|M.leprae_Br4923 -MTKLRHYLERGAAEVHYLRSIFESGALGFEPPLTYAAMAVAMRKWGDLA
MAV_1639|M.avium_104 AVLDRRAEQHPDRVMMSIAGVDVTFAQMRQRSCAAANMLSDLGVGRGDRV
Mvan_0898|M.vanbaalenii_PYR-1 GLLRKCVDEHPDTLFLDLAGDTYSYADVWQRSCDLAGMLHAGGVGAGQTV
TH_2476|M.thermoresistible__bu RALALQADAIGDAPFLASGDRRYSYGEANETVNRYANSLRALGVEAGDPV
Mb1238|M.bovis_AF2122/97 TVFQDRAARYGDRVFLKFGDQQLTYRDANATANRYAAVLAARGVGPGDVV
Rv1206|M.tuberculosis_H37Rv TVFQDRAARYGDRVFLKFGDQQLTYRDANATANRYAAVLAARGVGPGDVV
MMAR_4232|M.marinum_M TVFQDRAARFGDRVFLKFGDQQMTYGEANATANRYAAVLAARGVGPGDVV
MUL_0957|M.ulcerans_Agy99 TVFQDRAARFGDRVFLKFGDQQMTYGEANATANRYAAVLAARGVGPGDVV
Mflv_2185|M.gilvum_PYR-GCK KVFQDRAAQYSNNVFLKFEDREITYGEANEIVNRYAAVLAAKGVGHGDVV
MSMEG_5086|M.smegmatis_MC2_155 KVFQDRAAQYADRVFIKFGDERLTYKTANETVNRYAAVLAARGVGHGDVV
MAB_3628c|M.abscessus_ATCC_199 AMLLDRVGDS--HLGLRTRDRDWTWDQVVDESAARGALARKLRADGPFHI
MLBr_02546|M.leprae_Br4923 MLPAMPARRSPHRAALIDEEGTLTYKELDRAAHALANGLIAKGVRGGDGI
. : :: . . :
MAV_1639|M.avium_104 ALFSGTCPEWVYFWLGAARIGAVSAAINAAHKGDFLLHALRLCRPAVIFT
Mvan_0898|M.vanbaalenii_PYR-1 VSLQDTQIDAIASWFGANMLGAIWVGTNTALRGEFLRHVITDTGARVVVA
TH_2476|M.thermoresistible__bu AMLMDNSLEFVFTALGTNKLGAMWVPTNTSYRGEWLARTFVDGGAKVLVV
Mb1238|M.bovis_AF2122/97 GIMLRNSPSTVLAMLATVKCGAIAGMLNYHQRGEVLAHSLGLLDAKVLIA
Rv1206|M.tuberculosis_H37Rv GIMLRNSPSTVLAMLATVKCGAIAGMLNYHQRGEVLAHSLGLLDAKVLIA
MMAR_4232|M.marinum_M GIMLRNSPNTVVAMLAVVKCGAIAGMLNYHQRGEVLAHSLGLLDAKVLVA
MUL_0957|M.ulcerans_Agy99 GIMLRNSPNTVVAMLAVVKCGAIAGMLNYHQRGEVLAHSLGLLDAKVLVA
Mflv_2185|M.gilvum_PYR-GCK GIMMRNSPEPILLMLAAVKCGAISGMLNYHQRDEVLKHSVGLLSASVMVA
MSMEG_5086|M.smegmatis_MC2_155 GVMLRNSPDAVLLMLAIVKCGAIAGMLNYHQRGDVLKHSIGLLSATAVVA
MAB_3628c|M.abscessus_ATCC_199 GVLLDNVPDFVFWLGGAALAGATIVGINPTRGPAEMAAEIRHTDCQLIVT
MLBr_02546|M.leprae_Br4923 AILARNHRWFVIANYGCARVGARIILLNSEFSGPQIKEVSEREGAKVIIY
: . : . ** * : :.
MAV_1639|M.avium_104 DPEHRSRAERAAAALEGPARIVVQGDSLTAT--------LSRAADR--AP
Mvan_0898|M.vanbaalenii_PYR-1 EADLVDRIRAIGQHLPDVDLVLQRGDERPAADPHL---RIERLVDLGGHT
TH_2476|M.thermoresistible__bu DESLLDRATDNGLARR-FERVVVNGDPAAIADEAVRQRAVALADFAEGAG
Mb1238|M.bovis_AF2122/97 ESDLVSAVAECGASRGRVAGDVLTVEDVERFATTAP-----------ATN
Rv1206|M.tuberculosis_H37Rv ESDLVSAVAECGASRGRVAGDVLTVEDVERFATTAP-----------ATN
MMAR_4232|M.marinum_M ESDLVSAVSESGG----AAGEVVTIEDLERFAATAP-----------ANN
MUL_0957|M.ulcerans_Agy99 ESDLVSAVSESGG----AAGEVVTIEALERFAATAP-----------ANN
Mflv_2185|M.gilvum_PYR-GCK ETDFVEPITESGA----DTDGLMTLDELKKLAETAP-----------TTN
MSMEG_5086|M.smegmatis_MC2_155 EPDFVDHIVESGA----DTTGLMTVEELRRLATTAP-----------TTN
MAB_3628c|M.abscessus_ATCC_199 DTAHLGRLQSLELGLSADRLLVIDSPEYLQRIAESR------------CT
MLBr_02546|M.leprae_Br4923 DDEYTKVVSKAEPALGKLRALGVNPDEEEPPGSTDET-----LAELIARS
:
MAV_1639|M.avium_104 AEDRGD--AGELGCLFYTSGTTGPSKA-VATTWHYLFSVAATVAAAWEFR
Mvan_0898|M.vanbaalenii_PYR-1 VNEPGDGAVDDLTCLTYTGGTTGPSKG-CMISNGYAINIARRGLAQTQRQ
TH_2476|M.thermoresistible__bu TEVTSSADAATISSVMWTSGTTGRSKG-VMQPYGAWYAAARIFASARDLA
Mb1238|M.bovis_AF2122/97 PASASAVQAKDTAFYIFTSGTTGFPKASVMTHHRWLRALAVFGGMGLRLK
Rv1206|M.tuberculosis_H37Rv PASASAVQAKDTAFYIFTSGTTGFPKASVMTHHRWLRALAVFGGMGLRLK
MMAR_4232|M.marinum_M PASASAVQAQDTAFYIFTSGTTGFPKASVMTHHRWLRALAVFGGLGLRLK
MUL_0957|M.ulcerans_Agy99 PASASAVQAQDTAFYIFTSGTTGFPKASVMTHHRWLRALAVFGGLGLRLK
Mflv_2185|M.gilvum_PYR-GCK PATTSAVLAKDKAFYIFTSGTTGMPKASVMTHYRWLRALAGFGGLGMRLN
MSMEG_5086|M.smegmatis_MC2_155 PASASAVLAKDKAFYIFTSGTTGLPKASVMTHYRWLRALAGFGGLGLRLR
MAB_3628c|M.abscessus_ATCC_199 AQASEGVGADSLLLLLFTSGTTGASKA-VKCSQGRLAQIAHLATEKFGHV
MLBr_02546|M.leprae_Br4923 SSAPAPKVRKRASIIILTSGTTGTPKGANRNTPASLAPLGGILSK-VPFR
*.**** .*. .
MAV_1639|M.avium_104 QGEVLWTAMPLFHLS-AAPSVLAPMLVGATTVLAAAFHPREVWDDIRAHG
Mvan_0898|M.vanbaalenii_PYR-1 TDELNWSPLPMFHLNVLAMTLIGTMLVGGSAALAQRFSASRFWPEIERTG
TH_2476|M.thermoresistible__bu PGDVLYCCVPLFNSGGWSLNVFQALYSGLSIAIDREFSVSRFWDRVRRYG
Mb1238|M.bovis_AF2122/97 GSDTLYSCLPLYHNNALTVAVSSVINSGATLALGKSFSASRFWDEVIANR
Rv1206|M.tuberculosis_H37Rv GSDTLYSCLPLYHNNALTVAVSSVINSGATLALGKSFSASRFWDEVIANR
MMAR_4232|M.marinum_M SSDTLYSCLPLYHNNALTVAVSSVINSGATLALGKSFSASRFWDEVIASN
MUL_0957|M.ulcerans_Agy99 SSDTLYSCLPLYHNNALTVAVSSVINSGATLALGKSFSASRFWDEVIASN
Mflv_2185|M.gilvum_PYR-GCK SNDTLYCCLPLYHNNALTVALSSVLNSGATLAIGKSFSASKFWDDVIRYD
MSMEG_5086|M.smegmatis_MC2_155 SNDTLYCCLPLYHNNALTVSVGSVLNSGASLALGKSFSASRFWDEVIDYG
MAB_3628c|M.abscessus_ATCC_199 RSDVDYCCMPLFHGNALMALWAPALANGATVCLTPTFSASRFLPDVRYFG
MLBr_02546|M.leprae_Br4923 AHEVTLLPAPMFHALGYLHATLAMFLG-STLVLRRRFKPATVLEDIEKHQ
: *::: : : : * . :
MAV_1639|M.avium_104 AVGFAGAGAMVSMLQNLPADPGDARLP----LRFISAAPIDARSYRDIEK
Mvan_0898|M.vanbaalenii_PYR-1 ARVVNLIGGLPAILAQQPDTLEMARCFG--QIRMVHAVPFPPALQEIWRN
TH_2476|M.thermoresistible__bu ATQLLTLGSMHMYLWQREERDDDADNP----ARVAGLLPLPAEIREAFQK
Mb1238|M.bovis_AF2122/97 ATAFVYIGEICRYLLNQPAKPTDRAHQ----VRVICGNGLRPEIWDEFTT
Rv1206|M.tuberculosis_H37Rv ATAFVYIGEICRYLLNQPAKPTDRAHQ----VRVICGNGLRPEIWDEFTT
MMAR_4232|M.marinum_M ATAFIYIGEVCRYLLNQPTKPTDRKHK----VRVIAGNGLRPEIWGEFTK
MUL_0957|M.ulcerans_Agy99 ATAFIYIGEVCRYLLNQPTKPTDRKHK----VRVIAGNGLRPEIWGEFTK
Mflv_2185|M.gilvum_PYR-GCK ATAFVYIGEICAYLLNQPEKPTDRKHK----VRVICGNGLRPAIWDDFTK
MSMEG_5086|M.smegmatis_MC2_155 ATAFVYIGEICGYLLNQPPKPTDRAHK----VRVIVGNGLRPAIWDEFIE
MAB_3628c|M.abscessus_ATCC_199 ATFFTYVGKALGYLLATPERADDADNQ----LARGFGTEASPEDQAQFRR
MLBr_02546|M.leprae_Br4923 ATAMVVVPVMLSRILDTLENLETKSDLSSLRVVFVSGSQLGAELATRALE
* . : .
MAV_1639|M.avium_104 RYGCRIVT--------MYGMTEAFPIAVKALADAGI-PGTSGRPN-PDFE
Mvan_0898|M.vanbaalenii_PYR-1 RFGVKVPGSK------GYGMTEVFPITYQTPDEQSP-AESAGRINHEDLE
TH_2476|M.thermoresistible__bu RFGLERIWR-------GYGQSEIMPLSVSTPEREGN-PAGDGFPR-PDVE
Mb1238|M.bovis_AF2122/97 RFGVARVCEFYAASEGNSAFINIFNVPRTAGVSPMP-LAFVEYDLDTGDP
Rv1206|M.tuberculosis_H37Rv RFGVARVCEFYAASEGNSAFINIFNVPRTAGVSPMP-LAFVEYDLDTGDP
MMAR_4232|M.marinum_M RFDIDRVCEFYAASEGNSAFINIFNVPKSTGISPMP-LAYVAYDPDTGAP
MUL_0957|M.ulcerans_Agy99 RFDIDRVCEFYAASEGNSAFINIFNVPKSTGISPMP-LAYVAYDPDTGAP
Mflv_2185|M.gilvum_PYR-GCK RFGIDRVCEFYSASESNTAFVNFFNLDKTTGICPSP-IAFVEYD-ESGDP
MSMEG_5086|M.smegmatis_MC2_155 RFGISRVCEFYAASEGNTAFVNVFNVSKSTGICPSP-VAFVEYDPDTGEP
MAB_3628c|M.abscessus_ATCC_199 RFGAELFEGYGSSEGGGAVVLDPAAPPGALGRPAHEGVVVVDPETLQDCA
MLBr_02546|M.leprae_Br4923 ELGPVIYNMYG---------STEIAFATIAGPKDLQINSATVGPVVKGVK
. . .
MAV_1639|M.avium_104 VRILDAHGNSLPP-DTVGEIACRPRHPHVMSEGYIG--DDLAVRPH----
Mvan_0898|M.vanbaalenii_PYR-1 VRIVDERDDDVKP-GEVGEVICRPRRSHVMFQGYWRRPDAMVDSCR----
TH_2476|M.thermoresistible__bu VALLDERGREVPV-GEVGEICVRPRRPDVMFRGYYNNEEGTAKAWR----
Mb1238|M.bovis_AF2122/97 LRDASGRVRRVPD-GEPGLLLSRVNR-LQPFDGYTDPVASEKKLVRNAFR
Rv1206|M.tuberculosis_H37Rv LRDASGRVRRVPD-GEPGLLLSRVNR-LQPFDGYTDPVASEKKLVRNAFR
MMAR_4232|M.marinum_M LRDESGRVRRVPA-GEPGLLLSRVNR-LQPFDGYTDPAASEKKLVRDAFR
MUL_0957|M.ulcerans_Agy99 LRDESGRVRRVPA-GEPGLLLSRVNR-LQPFDGYTDPAASEKKLVRDAFR
Mflv_2185|M.gilvum_PYR-GCK LRDENGRVKKVKK-GEPGLLLSKVSN-FQPFDGYTDKKESEKKLVRDAFK
MSMEG_5086|M.smegmatis_MC2_155 VRGADGKLRKVKS-GEPGLLLSKVSS-FQPFDGYTDSSATEKKLVRNAFK
MAB_3628c|M.abscessus_ATCC_199 AAVFDQHGRVLNADAAVGEIVDKQGR--RGFEGYYNNDDADADRIR----
MLBr_02546|M.leprae_Br4923 VKILDDSGKEVPR-GQVGRIFVGNAF---PFEGYTGGGGKQI--------
. : * : **
MAV_1639|M.avium_104 --PEWFRTGDLGRLDRDQNLTYVDRIKDALRRRGENISSVEVETVVMGHP
Mvan_0898|M.vanbaalenii_PYR-1 --NLWFHTGDLGRIDDAGYFYFADRKHDYLRRRGENISSQELETTYVAHP
TH_2476|M.thermoresistible__bu --DGWYHSNDLGRFDEAGELYFVDRASDYMRHKGRNIPSLELEELIGRHP
Mb1238|M.bovis_AF2122/97 DGDCWFNTGDVMSPQGMGHAAFVDRLGDTFRWKGENVATTQVEAALASDQ
Rv1206|M.tuberculosis_H37Rv DGDCWFNTGDVMSPQGMGHAAFVDRLGDTFRWKGENVATTQVEAALASDQ
MMAR_4232|M.marinum_M KGDCWFNTGDVMSPQGMGHAAFVDRLGDTFRWKGENVATTQVEAALASDP
MUL_0957|M.ulcerans_Agy99 KGDCWFNTGDVMSPQGMGHAAFVDRLGDTFRWKGENVATTQVEAALASDP
Mflv_2185|M.gilvum_PYR-GCK DGDVWFNTGDLMRSQGFGHAAFTDRLGDTFRWKGENVATTEVEAAVSTDP
MSMEG_5086|M.smegmatis_MC2_155 DGDVWFNTGDLMRSQGFGHAAFADRLGDTFRWKGENVATTEVEAAVASHH
MAB_3628c|M.abscessus_ATCC_199 --NGWYWTGDLGYLDAAGFIYFAGRRGDWIRVDGENMSALTVERVLRRHP
MLBr_02546|M.leprae_Br4923 -IDGLLSSGDVGYFDEHDLLYISGRDDEMIVSGGENVFPAEVEDLISGHP
:.*: : .* : : *.*: . :* .
MAV_1639|M.avium_104 AVAEAAAVGVPG--ELGEDDVLVVVTLRPGATLDCAELLDFC--ADRMPY
Mvan_0898|M.vanbaalenii_PYR-1 DIVAVAVHAVPS--ELTEDDVKVTVVLRPGSVLTPAELFEWS--KERVPY
TH_2476|M.thermoresistible__bu AVYEVAAHGVPSQDLAEEDEVKICVILREGHELEPEELIRFI--NERAPY
Mb1238|M.bovis_AF2122/97 TVEECTVYGVQIP-RTGGRAGMAAITLRAGAEFDGQALARTV--YGHLPG
Rv1206|M.tuberculosis_H37Rv TVEECTVYGVQIP-RTGGRAGMAAITLRAGAEFDGQALARTV--YGHLPG
MMAR_4232|M.marinum_M SVEECTVYGVEVP-NTGGRAGMAAVKLRDGAEFDGQSLARAV--YDQLPA
MUL_0957|M.ulcerans_Agy99 SVEECTVYGVEVP-NTGGRAGMAAVKLRDGAEFDGQSLVRAV--YDQLPA
Mflv_2185|M.gilvum_PYR-GCK QVEEATVFGVEVP-DTGGRAGMVAIQLKDGKEFDGKALAKAA--FDKLPG
MSMEG_5086|M.smegmatis_MC2_155 KIEECTVFGVEVP-GAGGRAGMAAVQLKDGEEFDGKALADAF--YGHLPA
MAB_3628c|M.abscessus_ATCC_199 LVIAAGVYAVPDP--RSGDQVMASIEVAEPDSFDVDGFTQYLSAQEELGS
MLBr_02546|M.leprae_Br4923 EVVEATAIGVDDK--EWGARLRAFVVKKQDATIDEDAIKAYVR--DHLAR
: . .* : : : .
MAV_1639|M.avium_104 FCVPRYVETVPELPKNAIGRIRKDLLRARGLT------------------
Mvan_0898|M.vanbaalenii_PYR-1 FALPRYVEFRTELPTSPLGRVHKYLLREQGCT------------------
TH_2476|M.thermoresistible__bu FMVPRYVEFVTELPHTPTGRVQKFKLRERGVT------------------
Mb1238|M.bovis_AF2122/97 YALPLFVRVVGSLAHTTTFKSRKVELRNQAYG----------ADIEDPLY
Rv1206|M.tuberculosis_H37Rv YALPLFVRVVGSLAHTTTFKSRKVELRNQAYG----------ADIEDPLY
MMAR_4232|M.marinum_M YALPLFVRLVQAMAHTTTFKSRKVELREQAYG----------ADVDDPLY
MUL_0957|M.ulcerans_Agy99 YALPLFVRLVQAMAHTTTFKSRKVELREQAYG----------ADVDDPLY
Mflv_2185|M.gilvum_PYR-GCK YAVPLFVRIVEELAHTSTFKSQKGDLRKEGYGGSSGEGDEDDVKVEDPIY
MSMEG_5086|M.smegmatis_MC2_155 YAVPLFVRVVPELAHTSTFKSQKVDLRKQGYG----------PDVTDPVY
MAB_3628c|M.abscessus_ATCC_199 KGIPRFLRISANLPVTGSNKVLKRELQEQRWHTDEP----VFRWVGRGGP
MLBr_02546|M.leprae_Br4923 YKVPREVIFLEELPRNPTGKVLKRELRDFEVH------------------
:* : :. . : * *:
MAV_1639|M.avium_104 ---------TNVWDREKHGYVVRR----
Mvan_0898|M.vanbaalenii_PYR-1 ---------PETWDREAAGVSWDRR---
TH_2476|M.thermoresistible__bu ---------PDTWDREAAGLVLER----
Mb1238|M.bovis_AF2122/97 VLAGPDEGYVPYYAEYPEEVSLGRRPQG
Rv1206|M.tuberculosis_H37Rv VLAGPDEGYVPYYAEYPEEVSLGRRPQG
MMAR_4232|M.marinum_M VLAGRSEGYVPYYDAYPDEVAAGKRPQG
MUL_0957|M.ulcerans_Agy99 VLAGRSEGYVPYYDAYPDEVAAGKRPQG
Mflv_2185|M.gilvum_PYR-GCK VLSGREEGYVEFYEEYLVEVKDGKKPT-
MSMEG_5086|M.smegmatis_MC2_155 VLAGRDEGYVPFYDEYPEEVTAGKRPKN
MAB_3628c|M.abscessus_ATCC_199 VFLRMSSDDKTALDAQFAVYGRQRLL--
MLBr_02546|M.leprae_Br4923 ----------------------------