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M. avium 104 MAV_1266 (-)

annotation: nitroreductase family protein
coordinates: 1211216 - 1211863
length: 215

NVEYLLTATPSARKSLDLDAPVEPGDIRECLRIGLQAANGSNAQSWRWLVVSDPALRARIAELYRDAYLR
RVGGRLLAGLMPAGTPESRIMSSTEWLVENLARVPMLVIPCYEPYLPRIDGDESFHLATLYGSIFPPVWN
FQLALHTRGYGTCITTLHLHHEDEVAQLLGIPPTYVQGCLLPVGRLRAGRTFRPARRRPIQEVIACDRWD
GPPL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1266--100% (215)nitroreductase family protein
M. avium 104MAV_4334-8e-3539.81% (216) nitroreductase family protein
M. avium 104MAV_0933-6e-1328.64% (199) nitroreductase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3403c-2e-3440.00% (220) oxidoreductase
M. gilvum PYR-GCKMflv_4892-3e-3237.96% (216) nitroreductase
M. tuberculosis H37RvRv3368c-2e-3440.00% (220) oxidoreductase
M. leprae Br4923MLBr_00418-3e-3238.43% (216) putative oxidoreductase
M. abscessus ATCC 19977MAB_3693c-2e-3437.50% (216) oxidoreductase
M. marinum MMMAR_1160-3e-3138.25% (217) nitroreductase
M. smegmatis MC2 155MSMEG_1635-6e-3236.62% (213) nitroreductase family protein
M. thermoresistible (build 8)TH_2121-1e-3640.27% (221) POSSIBLE OXIDOREDUCTASE
M. ulcerans Agy99MUL_2854-2e-3137.84% (222) nitroreductase
M. vanbaalenii PYR-1Mvan_1532-2e-3137.44% (219) nitroreductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4892|M.gilvum_PYR-GCK          -MTLNLSADEVLTTTRSVRKRLDFDRPVPREVLNECLEIALQAPTGSNAQ
Mvan_1532|M.vanbaalenii_PYR-1       -MTLNLSADEVLTTTRSVRKRLDFDKPVPRDVLMECLDIALQAPTGSNNQ
MSMEG_1635|M.smegmatis_MC2_155      -MTLNLSVDELLTTTRSVRKRLDFEKPVSREVILECLDLALQAPTGSNAQ
TH_2121|M.thermoresistible__bu      -MALNLSVDDVLTTTRSVRKRLDLEKPVPREVLMECLELALQAPTGSNAQ
Mb3403c|M.bovis_AF2122/97           -MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTGSNSQ
Rv3368c|M.tuberculosis_H37Rv        -MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLELALQAPTGSNSQ
MMAR_1160|M.marinum_M               -MTLNLSVDEVLTTTRSVRKRLDFDKPVSREVLMECLDLALQAPTGSNSQ
MUL_2854|M.ulcerans_Agy99           -MTLNLSVDEVLTTTRSVRKRLDFDKPVSREVLMECLDLALQAPTGSNSQ
MLBr_00418|M.leprae_Br4923          -----MSVDEVLTTTRSVRKRLDFDKPVPRDVLMECLQLALQAPTGSNSQ
MAB_3693c|M.abscessus_ATCC_199      MTSLNLSADEVLTTTRSVRKRLDFDKPVERAVVEECLNIAMQAPTGSNHQ
MAV_1266|M.avium_104                -----MNVEYLLTATPSARKSLDLDAPVEPGDIRECLRIGLQAANGSNAQ
                                         :..: :**:* *.** **:: **    : *** :.:**..*** *

Mflv_4892|M.gilvum_PYR-GCK          GWQFVFVDDPEKKKALADIYRIAADPYLEAEKPTF--GDVRDER-TPLVV
Mvan_1532|M.vanbaalenii_PYR-1       GWQWVFVEDPEKKKAIADIYRTNATPYLAMEKPAT--GDMRDGQ-RPRVE
MSMEG_1635|M.smegmatis_MC2_155      GWQWVFVEDEAKKKALADIYRSNAIPYLEQEAAER--GDIRDQQ-QPKVR
TH_2121|M.thermoresistible__bu      GWQWVFVEDPDTKKALADIYRVNADAYLDRPRPSY--DDVRGER-MDRVK
Mb3403c|M.bovis_AF2122/97           GWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDGDTRGER-MGRVR
Rv3368c|M.tuberculosis_H37Rv        GWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDGDTRGER-MGRVR
MMAR_1160|M.marinum_M               GWQWVFVEDADKKKAIAEVYLARARSYLSMPAPEYAEGDTRGER-MGKVR
MUL_2854|M.ulcerans_Agy99           GWQWVFVEDADKKKAIADVYLARARSYLSMPAPEYAEGDTRGER-MGKVR
MLBr_00418|M.leprae_Br4923          GWHWVFVEDAEKRKAIGDIYLVNARCYLSQPAPEYPEGDTRGER-MRLVR
MAB_3693c|M.abscessus_ATCC_199      GWHWVIVEDAEKKKAIADIYREGWNKYAKGAGATYAEGDTRAER-KAKVV
MAV_1266|M.avium_104                SWRWLVVSDPALRARIAELYR---DAYLRRVGGRLLAGLMPAGTPESRIM
                                    .*:::.*.*   :  :.::*      *          .          : 

Mflv_4892|M.gilvum_PYR-GCK          DSAKYLAEHLHEAPVMLIPCLE---GRPDGAPAGMSAGFWGSLLPAVWSF
Mvan_1532|M.vanbaalenii_PYR-1       DSARYLNEHLEKVPVMLIPCLQ---GKPQDAVSGASAGYWGSLLPAVWSF
MSMEG_1635|M.smegmatis_MC2_155      DSARHLTDNFEKAPVLLIPCLE---GRPDGAPAGLSASFWGSLLPAVWSF
TH_2121|M.thermoresistible__bu      SSARYLSEHFHEVPVLLVPCLE---GRPDNQPAGVTASFWGSLLPAVWSF
Mb3403c|M.bovis_AF2122/97           DSATYLAEHMHRAPVLLIPCLK---GREDESAVGG-VSFWASLFPAVWSF
Rv3368c|M.tuberculosis_H37Rv        DSATYLAEHMHRAPVLLIPCLK---GREDESAVGG-VSFWASLFPAVWSF
MMAR_1160|M.marinum_M               DSATYLAEHMHEAPVLMIPCIQ---GREDKSPLGG-VSFWASLFPAVWSF
MUL_2854|M.ulcerans_Agy99           DSATYLAEHMHEAPVLMIPCIQ---GREDKSPLGG-VSLWASLFPAVWSF
MLBr_00418|M.leprae_Br4923          DSATYLAEHMHEVPVLLIPCLL---GRAEESPLGA-VSYWASLFPAVWSF
MAB_3693c|M.abscessus_ATCC_199      DSAGYLAENFERSPLFLIPCIE---GRLDNLPVVGAASSWGSLLPAVWSF
MAV_1266|M.avium_104                SSTEWLVENLARVPMLVIPCYEPYLPRIDGDESFHLATLYGSIFPPVWNF
                                    .*:  * ::: . *::::**      : :       .  :.*::*.**.*

Mflv_4892|M.gilvum_PYR-GCK          MLALRSRGLGSAWTTLHLIGDGEKQAAEVLGIPFDKYSQGGLFPIA-YTK
Mvan_1532|M.vanbaalenii_PYR-1       MLALRSRGLGSAWTTLHLLGDGERQAAEILGIPFDNYSQAGLFPIA-YTK
MSMEG_1635|M.smegmatis_MC2_155      MLALRSRGLGSAWTTLHLLGEGEKQAAEVVGIPFDKYSQAGLFPIA-YTI
TH_2121|M.thermoresistible__bu      MLALRSRGLGSAWTTLHLVGDGEQRAAEVLGIPFDRYSQAGLFPIA-YTK
Mb3403c|M.bovis_AF2122/97           CLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGLLPIA-YTQ
Rv3368c|M.tuberculosis_H37Rv        CLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGLLPIA-YTQ
MMAR_1160|M.marinum_M               CLALRSRGLGSCWTTLHLLADGERQVADVLGIPYDDYSQGGLFPIA-YTK
MUL_2854|M.ulcerans_Agy99           CLALRSRGLGSCWTTLHLLADGERQVADVLGIPYDDYSQGGLFPIA-YTK
MLBr_00418|M.leprae_Br4923          CLALRSRGLGTCWTSLHLLGDGEQRAAEVLGIPSDKYSQGGLFPIA-YTK
MAB_3693c|M.abscessus_ATCC_199      MLAARNRGLGSAWTTLHLMDDGEKRTADIVGIPFDKVTQGGLFPIA-YTV
MAV_1266|M.avium_104                QLALHTRGYGTCITTLHLHH--EDEVAQLLGIP-PTYVQGCLLPVGRLRA
                                     ** :.** *:. *:***    * ..*:::***     *. *:*:.    

Mflv_4892|M.gilvum_PYR-GCK          GTDFKKAKRLPAEQLTHWNTW-----
Mvan_1532|M.vanbaalenii_PYR-1       GTDFRRAKRLPAEQLTHWDTW-----
MSMEG_1635|M.smegmatis_MC2_155      GTDFKKAKRLPAEQFAHWDTW-----
TH_2121|M.thermoresistible__bu      GTDFRPAKRLPAEQVVHWNRW-----
Mb3403c|M.bovis_AF2122/97           GIDFRPAKRLPAESVTHWNGW-----
Rv3368c|M.tuberculosis_H37Rv        GIDFRPAKRLPAESVTHWNGW-----
MMAR_1160|M.marinum_M               GTDFRPAKRLPADRLTHWNSW-----
MUL_2854|M.ulcerans_Agy99           GTDFRPAKRLPADRLTHWNSW-----
MLBr_00418|M.leprae_Br4923          GTDFRPANRLPAENVTHWDIW-----
MAB_3693c|M.abscessus_ATCC_199      GTDFRLAKRQPLADVLHWDTW-----
MAV_1266|M.avium_104                GRTFRPARRRPIQEVIACDRWDGPPL
                                    *  *: *.* *   .   : *