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PEPIPSAAEALARLDMPLVEAMMTQRAIRRVLPDPVDDEIVLKCLELALRAPTGANGQNWEFVVVKDPKI KRKLQRRYRLAWRVFHRTSIRDIASYDEEMAKSVRAIEWQLEHFHEIPVLVIACLRLSAREGKVPYVPMP HAAASAFFGSIYPSVQNLLLAARAMGLGASLITLPLWNLTSARRVLKLPTEVTPCCVVPLGWPRGRYGPT TRRPVDEVVHLDRYGNRAWFGPRGADRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3115 | - | - | 100% (239) | nitroreductase |
| M. vanbaalenii PYR-1 | Mvan_5547 | - | 2e-21 | 31.38% (239) | nitroreductase |
| M. vanbaalenii PYR-1 | Mvan_1532 | - | 2e-19 | 26.36% (220) | nitroreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3403c | - | 2e-19 | 30.56% (216) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3382 | - | 1e-101 | 69.83% (232) | nitroreductase |
| M. tuberculosis H37Rv | Rv3368c | - | 2e-19 | 30.56% (216) | oxidoreductase |
| M. leprae Br4923 | MLBr_00418 | - | 5e-20 | 29.72% (212) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3693c | - | 8e-22 | 30.49% (223) | oxidoreductase |
| M. marinum M | MMAR_2938 | - | 3e-67 | 59.53% (215) | nitroreductase |
| M. avium 104 | MAV_4334 | - | 3e-23 | 31.82% (220) | nitroreductase family protein |
| M. smegmatis MC2 155 | MSMEG_6627 | - | 3e-20 | 34.29% (210) | nitroreductase family protein |
| M. thermoresistible (build 8) | TH_2448 | - | 1e-104 | 75.86% (232) | PUTATIVE nitroreductase |
| M. ulcerans Agy99 | MUL_2198 | - | 2e-67 | 59.53% (215) | nitroreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3115|M.vanbaalenii_PYR-1 ---MPEPIPSAAEALARLDMPLVEAMMTQRAIRR--VLPDPVDDEIVLKC
TH_2448|M.thermoresistible__bu MPDTPKPIPSVAEALARLDMPLAEAMMTQRAVRR--VLPDPVDDELVLKC
Mflv_3382|M.gilvum_PYR-GCK ---MADPTPSTSEALARLDMSLIDVMMTQRAVRR--VYPDPVDDEIVMKC
MMAR_2938|M.marinum_M -------------------MPLEDAMRTQRSIRR--LKSDPVDDSLVLHL
MUL_2198|M.ulcerans_Agy99 -------------------MPLEDAMRTQRSIRR--LKSDPVDDSLVLHL
Mb3403c|M.bovis_AF2122/97 ---------------MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMEC
Rv3368c|M.tuberculosis_H37Rv ---------------MTLNLSVDEVLTTTRSVRKRLDFDKPVPRDVLMEC
MLBr_00418|M.leprae_Br4923 -------------------MSVDEVLTTTRSVRKRLDFDKPVPRDVLMEC
MAV_4334|M.avium_104 ---------------MTLNLSVDEVLTTTRSVRKRLDFDKPVPREVLMEC
MAB_3693c|M.abscessus_ATCC_199 --------------MTSLNLSADEVLTTTRSVRKRLDFDKPVERAVVEEC
MSMEG_6627|M.smegmatis_MC2_155 --------------MPQPTNDVWEVLSTARSIRR--FTDEPVDDATLHRC
:.: * *::*: .** : .
Mvan_3115|M.vanbaalenii_PYR-1 LELALRAPTGANGQNWEFVVVKDPKIKRKLQRRYRLAWRVFHRTSIRDIA
TH_2448|M.thermoresistible__bu IELALRAPTGSNGQNWEFIVVKDPAVKAKLADRYRQAWAVYGGIGRR-VT
Mflv_3382|M.gilvum_PYR-GCK LEVALHAPTGANGQNWEFIVVKDYETKKKLAKRYRQAWNLYYQTVIRRVS
MMAR_2938|M.marinum_M LELAMKAPTGSNAQNWEFIVVKDREVVAKLGRLNRRAMQLFGPIYRRSIA
MUL_2198|M.ulcerans_Agy99 LELAMKAPTGSNAQNWEFIVVKDREVVAKLGRLNRRAMQLFGPIYRRSIA
Mb3403c|M.bovis_AF2122/97 LELALQAPTGSNSQGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYP
Rv3368c|M.tuberculosis_H37Rv LELALQAPTGSNSQGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYP
MLBr_00418|M.leprae_Br4923 LQLALQAPTGSNSQGWHWVFVEDAEKRKAIGDIYLVNARCYLSQPAPEYP
MAV_4334|M.avium_104 LELALQAPTGSNAQGWQWVFVEDADKKKAIADIYLANARAYLSLPAAEYP
MAB_3693c|M.abscessus_ATCC_199 LNIAMQAPTGSNHQGWHWVIVEDAEKKKAIADIYREGWNKYAKGAGATYA
MSMEG_6627|M.smegmatis_MC2_155 LQAAAWAPNGANAQLWRFVVLDAPEQRAAVAGAARSALATIESIYGMSRP
:: * **.*:* * *.::.:. : .
Mvan_3115|M.vanbaalenii_PYR-1 SY---DEEMAKSVRAIEWQLEHFHEIPVLVIACLRLSAREGKVPYVPMPH
TH_2448|M.thermoresistible__bu AG---DESMAKILRAVQWQVDHFTEIPVLVVACLRAGPREGRLPFMPAPP
Mflv_3382|M.gilvum_PYR-GCK KR---DPSMAKTARAVQWQVDHFTEVPVLIVACLKLGPKDGRIPFVPMPH
MMAR_2938|M.marinum_M RRG--DEKMLRLQKAVQWQADHFEEIPVVVVACLRG-------VIAPWPR
MUL_2198|M.ulcerans_Agy99 RRG--DEKMLRLQKAVQWQADHFEEIPVVVVACLRG-------VIAPWPR
Mb3403c|M.bovis_AF2122/97 DGDTRGERMGRVRDSATYLAEHMHRAPVLLIPCLKG-------REDESAV
Rv3368c|M.tuberculosis_H37Rv DGDTRGERMGRVRDSATYLAEHMHRAPVLLIPCLKG-------REDESAV
MLBr_00418|M.leprae_Br4923 EGDTRGERMRLVRDSATYLAEHMHEVPVLLIPCLLG-------RAEESPL
MAV_4334|M.avium_104 EGDTRGERMPKVKDSAVYLAEHMHEAPVLLIPCLEG-------RVENAPL
MAB_3693c|M.abscessus_ATCC_199 EGDTRAERKAKVVDSAGYLAENFERSPLFLIPCIEG-------RLDNLPV
MSMEG_6627|M.smegmatis_MC2_155 ADDD-HSRAARNNRATYELHDRAGELTSVLFVAYKN------------EF
: :. . . .:. .
Mvan_3115|M.vanbaalenii_PYR-1 AAASAFFGSIYPSVQNLLLAARAMGLGASLITLPLWN--LTSARRVLKLP
TH_2448|M.thermoresistible__bu VAASSFFGSIYPSVQNLLLAARAMGLGASLITLPLWS--MTSARRILKLP
Mflv_3382|M.gilvum_PYR-GCK AALSGFYGSIYPSVQNLLLAARAMGLGASLITLPLWS--VTSTRKTLGLP
MMAR_2938|M.marinum_M ISTSSAYGSIYPAVQNLLLAARAAGLGAGLITVPLWS--TVLARRALGLP
MUL_2198|M.ulcerans_Agy99 ISTSSAYGSIYPAVQNLLLAARAAGLGAGLITVPLWS--TVLARRALGLP
Mb3403c|M.bovis_AF2122/97 G-GVSFWASLFPAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIP
Rv3368c|M.tuberculosis_H37Rv G-GVSFWASLFPAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIP
MLBr_00418|M.leprae_Br4923 G-AVSYWASLFPAVWSFCLALRSRGLGTCWTSLHLLGDGEQRAAEVLGIP
MAV_4334|M.avium_104 GLSASFWASLFPAAWSFCLALRSRGLGTCWTTLHLINDGEKQAAELLGIP
MAB_3693c|M.abscessus_ATCC_199 VGAASSWGSLLPAVWSFMLAARNRGLGSAWTTLHLMDDGEKRTADIVGIP
MSMEG_6627|M.smegmatis_MC2_155 ASDYLQAGSIYPAMQNFYLAARAQGLGACFTSWAAYQ-GEQILRDAVGVP
.*: *: .: ** * ***: : : :*
Mvan_3115|M.vanbaalenii_PYR-1 TE-VTPCCVVPLGWPRGR-YGPTTRRPVDEVVHLDRYGNRAWFGPRGADR
TH_2448|M.thermoresistible__bu LS-VTPCCIVPLGWPRGR-YGPTTRRPVREVVHLDSYGNRAWQSPS----
Mflv_3382|M.gilvum_PYR-GCK VS-VTPCCVVPLGWPRGR-YGPTTRRPVAEVMHLNTYGNRPWMGTG----
MMAR_2938|M.marinum_M WN-VTPCAVVPLGWPIGK-YGPTTRRPVAEIVSLDRYGNRAFR-------
MUL_2198|M.ulcerans_Agy99 RN-VTPCAVVPLGWPIGK-YGPTTRRPVAEIVSLDRYGNRAFR-------
Mb3403c|M.bovis_AF2122/97 YDEYSQGGLLPIAYTQGIDFRPAKRLPAESVTHWNGW-------------
Rv3368c|M.tuberculosis_H37Rv YDEYSQGGLLPIAYTQGIDFRPAKRLPAESVTHWNGW-------------
MLBr_00418|M.leprae_Br4923 SDKYSQGGLFPIAYTKGTDFRPANRLPAENVTHWDIW-------------
MAV_4334|M.avium_104 HDRYSQGGLFPIAYTKGTDFRPAKRLPAEQVTHWDSW-------------
MAB_3693c|M.abscessus_ATCC_199 FDKVTQGGLFPIAYTVGTDFRLAKRQPLADVLHWDTW-------------
MSMEG_6627|M.smegmatis_MC2_155 AEWFLAG-HVVIGRPRGR-HGPVRRRPLDDVVFRNTWDAARADIVYGQGA
. . :. . * . . * * .: : :
Mvan_3115|M.vanbaalenii_PYR-1 P----
TH_2448|M.thermoresistible__bu -----
Mflv_3382|M.gilvum_PYR-GCK -----
MMAR_2938|M.marinum_M -----
MUL_2198|M.ulcerans_Agy99 -----
Mb3403c|M.bovis_AF2122/97 -----
Rv3368c|M.tuberculosis_H37Rv -----
MLBr_00418|M.leprae_Br4923 -----
MAV_4334|M.avium_104 -----
MAB_3693c|M.abscessus_ATCC_199 -----
MSMEG_6627|M.smegmatis_MC2_155 RPSRT