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M. thermoresistible (build 8) TH_2297 (-)

annotation: alpha-amylase 3
coordinates: 4503637 - 4504968
length: 444

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2297--100% (444)alpha-amylase 3
M. thermoresistible (build 8)TH_1780treS3e-1725.72% (416) trehalose synthase
M. thermoresistible (build 8)TH_0920-2e-1627.86% (384) PROBABLE ALPHA-GLUCOSIDASE AGLA (MALTASE) (GLUCOINVERTASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2498aglA5e-1826.96% (382) alpha-glucosidase AglA
M. gilvum PYR-GCKMflv_3333-0.068.03% (441) alpha amylase, catalytic region
M. tuberculosis H37RvRv2471aglA6e-1826.96% (382) alpha-glucosidase AglA
M. leprae Br4923MLBr_02045-2e-2153.93% (89) hypothetical protein MLBr_02045
M. abscessus ATCC 19977MAB_1565c-3e-1324.23% (388) Alpha-amylase family protein
M. marinum MMMAR_2753treS_11e-17667.05% (437) trehalose synthase TreS_1
M. avium 104MAV_2842-0.067.79% (444) alpha-amylase 3
M. smegmatis MC2 155MSMEG_3576-0.072.69% (443) alpha-amylase 3
M. ulcerans Agy99MUL_3001treS_11e-17666.37% (443) trehalose synthase TreS_1
M. vanbaalenii PYR-1Mvan_3059-0.070.75% (441) alpha amylase, catalytic region

CLUSTAL 2.0.9 multiple sequence alignment


TH_2297|M.thermoresistible__bu      -------------------------VTGPDWVRHTIWWQIYPLGFVGAHP
MSMEG_3576|M.smegmatis_MC2_155      -------------------------MTMPDWVTHAIWWQIYPLGFVGAHP
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                -------------------------MTGPDWVQHVIWWQVYPLGFVGAYP
MMAR_2753|M.marinum_M               -------------------------------MQHAIWWQVYPLGFVGAFP
MUL_3001|M.ulcerans_Agy99           -------------------------MSKPTWVQHAIWWQVYPLGFVGAFP
Mflv_3333|M.gilvum_PYR-GCK          -------------------------MSDPAWVEHVLWWQVYPLGFVGVHP
Mvan_3059|M.vanbaalenii_PYR-1       -------------------------MTEPDWVDHVVWWQVYPLGFVGAYP
Mb2498|M.bovis_AF2122/97            MDQHQRPDPMGPGSPRASARRPEPDPMGEPWWSRAVFYQVYPRSFADSNG
Rv2471|M.tuberculosis_H37Rv         MDQHQRPDPMGPGSPRASARRPEPDPMGEPWWSRAVFYQVYPRSFADSNG
MAB_1565c|M.abscessus_ATCC_199      ---------------MTAAYLGQHD---DPWWSRAVFYQIYPRSFGDSDG
                                                                                      

TH_2297|M.thermoresistible__bu      WTDPTTGPPGPDEHRLRRVLDWLDHVVDLGASGLALGPVFAS--RSHGYD
MSMEG_3576|M.smegmatis_MC2_155      -ADP---PPGPEEHRLRRIVEWLDHAVELGASGLALGPVFAS--RTHGYD
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                LPQSSE-PPQPEHHRLRRLVDWFDHAIELGASGIALGPIFTS--RTHGYD
MMAR_2753|M.marinum_M               ---ANQ-PPDPGEHRLRRLVGWFDHAVELGASGVALGPIFDS--RTHGYD
MUL_3001|M.ulcerans_Agy99           ---ANQ-PPNPGEHRLRRLVGWFDHAVELGASGVALGPIFDS--RTHGYD
Mflv_3333|M.gilvum_PYR-GCK          ---ADT-APEPGEHRLRRIVDWLDYAVELGASGVALGPVFHS--RTHGYD
Mvan_3059|M.vanbaalenii_PYR-1       ---ADP-PPPPGEHRLRRIVDWLDYAIELGASGLALGPVFAS--RTHGYD
Mb2498|M.bovis_AF2122/97            ----------DGVGDLDGLASRLDHLQQLGVDAIWINPVTVSPMADHGYD
Rv2471|M.tuberculosis_H37Rv         ----------DGVGDLDGLASRLDHLQQLGVDAIWINPVTVSPMADHGYD
MAB_1565c|M.abscessus_ATCC_199      ----------DGVGDIDGISAKLGYLDLLGVEGIWLNPVTRSPMADHGYD
                                                                                      

TH_2297|M.thermoresistible__bu      TTDHYRIDPRLGTDADFDELVEQAHRRGLRVLLDGVFHHVGTDFARYRDA
MSMEG_3576|M.smegmatis_MC2_155      TTDHLRIDPRLGDDADFDHVVAEAHRRGLRVLLDGVFNHVGTDFARYRQA
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                TTDHYRIDPRLGDDADFDHLIAQAHRRGLRVLLDGVFNHVGVDFPRYRAA
MMAR_2753|M.marinum_M               TTDHFRIDPRLGDEGDFDHLVAEAHRRGLRVLLDGVFNHVGMDFHRYRHA
MUL_3001|M.ulcerans_Agy99           TTDHFRIDPRLGDEGDFDHLVAEAHRRGLRVLLDGVFNHVGVDFHSYRHA
Mflv_3333|M.gilvum_PYR-GCK          TIDHYRVDPRLGDDSDFDHLIEESHSRGLRVLLDGVFNHVGTEFPRYREA
Mvan_3059|M.vanbaalenii_PYR-1       TTDHYRIDPRLGEDGDFDHLVAEARDRGLRILLDGVFNHVGTDFPRYRDA
Mb2498|M.bovis_AF2122/97            VADPRDIDPLFGGMPAFERLVAAAHRQGIKVTMDVVPNHTSSAHPWFQAA
Rv2471|M.tuberculosis_H37Rv         VADPRDIDPLFGGMPAFERLVAAAHRQGIKVTMDVVPNHTSSAHPWFQAA
MAB_1565c|M.abscessus_ATCC_199      VSNPREIDPLFGGSIAMHRLIASAHRHNIKVIMDLVPNHTSSEHPWFLEA
                                                                                      

TH_2297|M.thermoresistible__bu      AAG-------------------------------GSSGWFRRRG-----D
MSMEG_3576|M.smegmatis_MC2_155      LGGD-----------------------------ADSAAWFRHRD-----G
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                IDSD----------------------------DHAAARWFRGSR-----G
MMAR_2753|M.marinum_M               AD------------------------------DPSSAGWFRGRA-----G
MUL_3001|M.ulcerans_Agy99           AD------------------------------DPSSAGWFRGRA-----G
Mflv_3333|M.gilvum_PYR-GCK          VD-------------------------------GGDRSWFATRG-----D
Mvan_3059|M.vanbaalenii_PYR-1       AA-------------------------------GGDSAWFRRRG-----G
Mb2498|M.bovis_AF2122/97            LADLPGSPARDRYFFRDGRGPDGSLPPNNWESVFGGPAWTRVREPDGNPG
Rv2471|M.tuberculosis_H37Rv         LADLPGSPARDRYFFRDGRGPDGSLPPNNWESVFGGPAWTRVREPDGNPG
MAB_1565c|M.abscessus_ATCC_199      LQSPPGSDARERYIFRDGKGAHGELPPNNWPSVFGGPAWTRVTEADGTPG
                                                                                      

TH_2297|M.thermoresistible__bu      RFETFEGHDELIALDHDNPEVAAYTVDVLRHWLNRGADGWRLDAAYAVPD
MSMEG_3576|M.smegmatis_MC2_155      KFEVFEGHGELIALNHDNPEVVNYTAGVMRHWLGRGADGWRLDAAYAVPD
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                RFHTFEGHDGLITLNHDNPEVVDYTVDVMAHWLGRGADGWRLDAAYAVPE
MMAR_2753|M.marinum_M               NFRTFEGHSELITLNHANPEVADYVVDVMAHWLQRGADGWRLDAAYAVPQ
MUL_3001|M.ulcerans_Agy99           NFRTFEGHSGLITLNHANPEVADYVVDVMAHWLQRGADGWRLDAAYAVPQ
Mflv_3333|M.gilvum_PYR-GCK          DFATFEGHEGLITLDHDNADVVDYTVDVMSHWLARGADGWRLDAAYAVPD
Mvan_3059|M.vanbaalenii_PYR-1       DFATFEGHGDLIALDHRSAEVVDYTVDVMSHWLGRGADGWRLDAAYAVPD
Mb2498|M.bovis_AF2122/97            QWYLHLFDTEQPDLNSDNPEILDDFEKTLRFWLDRGVDGFRIDVAHGMAK
Rv2471|M.tuberculosis_H37Rv         QWYLHLFDTEQPDLNWDNPEILDDFEKTLRFWLDRGVDGFRIDVAHGMAK
MAB_1565c|M.abscessus_ATCC_199      QWYLHLFAPEQPDVNWDNPEVFDDFADTLRFWLDRGIDGFRLDVAHGMAK
                                                                                      

TH_2297|M.thermoresistible__bu      R-----------------------------FWARVLPDVRRSHPEAWFVG
MSMEG_3576|M.smegmatis_MC2_155      R-----------------------------FWAQVLPIVRSDFGDAWFVG
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                T-----------------------------FWAATLPRVRDRYPQAWFVG
MMAR_2753|M.marinum_M               Q-----------------------------FWAKVLPRVRDRYPRAWFVG
MUL_3001|M.ulcerans_Agy99           Q-----------------------------FWAKVLPRVRDRYPQAWFVG
Mflv_3333|M.gilvum_PYR-GCK          R-----------------------------FWAQVLPRVRQAHPAAWFVG
Mvan_3059|M.vanbaalenii_PYR-1       S-----------------------------FWAGVLPRVRERHPQAWFVG
Mb2498|M.bovis_AF2122/97            PPGLPDSPDLGIEVLHHRDDDPRFNHPNVHAIHRDIRTVIDEYPGAVTVG
Rv2471|M.tuberculosis_H37Rv         PPGLPDSPDLGIEVLHHRDDDPRFNHPNVHAIHRDIRTVIDEYPGAVTVG
MAB_1565c|M.abscessus_ATCC_199      PPGLPDIEDTETSMLHIADEDPRFNNEGVHEYHRKIRKVLDQYRDVVAVG
                                                                                      

TH_2297|M.thermoresistible__bu      EVIHGD---YAATVSAASFDSVTQYELWKAVWSSLNDGNFFELDWALQRH
MSMEG_3576|M.smegmatis_MC2_155      EVIHGD---YAATVAASTFDSVTQYELWKAVWSALNDGNFHELDWALQRH
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                ELIHGD---YAAVVRAAGFDSATQYELWKAIWSSLNDGNFYELDWALQRH
MMAR_2753|M.marinum_M               EIIHGD---YAAAVQGAGFDSVTQYELWKAIWSGLNDGNFFELDWALQRH
MUL_3001|M.ulcerans_Agy99           EIIHGD---YAAAVQGAGFDSVTQYELWKAIWSGLNDGNFFELDWALQRH
Mflv_3333|M.gilvum_PYR-GCK          EVIHGD---YVARVRDSGFDSVTQYELWKAVWSSINDANFHELDWALTRH
Mvan_3059|M.vanbaalenii_PYR-1       EVIHGD---YPARVRDSGFDSVTQYELWKAIWSSLNDGNFHELDWALTRH
Mb2498|M.bovis_AF2122/97            EVWVHDNARWAEYLRPDELHLGFNFRLARTEFDAAEIRDAVANSLAAAAL
Rv2471|M.tuberculosis_H37Rv         EVWVHDNARWAEYLRPDELHLGFNFRLARTEFDAAEIRDAVANSLAAAAL
MAB_1565c|M.abscessus_ATCC_199      EIWVNDNTRFAEYVRPDELHLGFNFKLVEADFDADQIRAAIQNSLAAVDS
                                                                                      

TH_2297|M.thermoresistible__bu      NDFLAVFTPLTFIGNHDVTRIASRLADRRHVEHAVVLLLTVGGVPSIYAG
MSMEG_3576|M.smegmatis_MC2_155      NDFLASFVPMTFVGNHDVTRIASQLSDARHLEHALVILFTTGGIPSVYAG
MLBr_02045|M.leprae_Br4923          -----------------MSRIASQLGQPEHLTHALIILLTVAGVPSVYAG
MAV_2842|M.avium_104                NAFLGRFSPLTFIGNHDVTRIASQLNNPAHLAHALVLLLTVGGVPSVYAG
MMAR_2753|M.marinum_M               NEFVASFAPLTFIGNHDVTRIASRLERPEHLAHALVILMTVGGIPSIYAG
MUL_3001|M.ulcerans_Agy99           NEFVASFAPLTFIGNHDVTRIASRLERPEHLAHALVILMTVGGIPSIYAG
Mflv_3333|M.gilvum_PYR-GCK          NEFLDTFVPLTFIGNHDVTRIASRLTDPAHVEHALVVLLTTGGTPSVYAG
Mvan_3059|M.vanbaalenii_PYR-1       DEFLDTFVPMTFVGNHDVTRIASQLTDPTHVEHALVLLMTVGGTPSVYAG
Mb2498|M.bovis_AF2122/97            QNATPTWTLANHDVGREVSRYGGGEIGLRRAKAMAVVMLALPGVVFLYNG
Rv2471|M.tuberculosis_H37Rv         QNATPTWTLANHDVGREVSRYGGGEIGLRRAKAMAVVMLALPGVVFLYNG
MAB_1565c|M.abscessus_ATCC_199      VGATPTWTLSNHDVEREVTRYGDGQIGQWRARAMALVMLALPGTVFIYNG
                                                     ::* ..      :     :::::  *   :* *

TH_2297|M.thermoresistible__bu      DEAGYLGVKE----------ERFSGDDAIRPEFGSPPIVS----GAGENT
MSMEG_3576|M.smegmatis_MC2_155      DEWGHQGVKE----------ERRGGDDAVRPEFGERP---------GPDA
MLBr_02045|M.leprae_Br4923          DEFGFRGLKE----------ERYGVDDAVLPEFFSPP--------MQLDV
MAV_2842|M.avium_104                DELGFRGVKE----------ERFGGDDAVRPEFGSPP--------IPLDD
MMAR_2753|M.marinum_M               DEFGWRAVKE----------ERYGGDDAIRPEFGSPP--------LQLTH
MUL_3001|M.ulcerans_Agy99           DEFGWRAVKE----------ERCGGDDAIRPEFGSPP--------FELTH
Mflv_3333|M.gilvum_PYR-GCK          DEVAYRGVKE----------ERFGGDDAVRPEFRSPF--------DGVGE
Mvan_3059|M.vanbaalenii_PYR-1       DEVAYRGVKE----------ERFGGDDAVRPEFGSPF--------EGVGE
Mb2498|M.bovis_AF2122/97            QELGLPDVDLPDEVLQDPTWERSGRTERGRDGCRVPIPWSGNIPPFGFST
Rv2471|M.tuberculosis_H37Rv         QELGLPDVDLPDEVLQDPTWERSGRTERGRDGCRVPIPWSGNIPPFGFST
MAB_1565c|M.abscessus_ATCC_199      SELGLPNVELPDEALQDPVWERSGHTERGRDGCRVPIPWEGTDPPYGFSS
                                    .* .   :.           ** .  :                       

TH_2297|M.thermoresistible__bu      VAADLVRLHQHLIGLRRRNPWLHTATTAPLHLTNTQYVYESRSGEHALVV
MSMEG_3576|M.smegmatis_MC2_155      PGADVLRLHQYLIGLRRRHPWLHSATTTPLLLTNTQYVYRSAGAAGALVV
MLBr_02045|M.leprae_Br4923          FGVHAWALHQYLIGLRRRHP------------------------------
MAV_2842|M.avium_104                FGTEVWRLHQYLIGLRRRHPWLHAATTTALLLQNRHYVYETRSGDEALLI
MMAR_2753|M.marinum_M               DQASVWALHQYLVGLRRRYPWLHTASTSALRLRNRQYVYQTRSADNALVV
MUL_3001|M.ulcerans_Agy99           DQASVWALHQYLVGLRRRYPWLHTASTSALRLRNRQYVYQTRSADNALVV
Mflv_3333|M.gilvum_PYR-GCK          QGHQMFRSHQHLIGLRRRHPWLHEARTTALSVTNTGYVYITRSGDDALVV
Mvan_3059|M.vanbaalenii_PYR-1       HGHQVFRSHQHLIGLRRRNPWLHTARTTPLRVTNRGYVYTTRHGDDALVV
Mb2498|M.bovis_AF2122/97            CPDTWLPMPPEWAALTAEKQRADAGSTLSFFRLALRLRRERNEFDG-DVD
Rv2471|M.tuberculosis_H37Rv         CPDTWLPMPPEWAALTAEKQRADAGSTLSFFRLALRLRRERNEFDG-DVD
MAB_1565c|M.abscessus_ATCC_199      NAQTWLPMPHGWAEYTVERQLEHTDSMLSLYRRAIELRKSRKEFTGTSLE
                                                     .                                

TH_2297|M.thermoresistible__bu      ALNIDTAPLPLRLSEIGLGAGRVVAGSGAPPAADLTNVDVAPHGWLIIEP
MSMEG_3576|M.smegmatis_MC2_155      ALNLDDAPLRVALPELGLASGVVVAGSKAPPQEQIEVTEVPPHGWLVIEP
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                VLNIGDEPLRVSLDELGGRRGRVIGGSAAPPPEVLDTVVVEPQGWRILSP
MMAR_2753|M.marinum_M               ILNADDEPLRMSLPDLGIPRAEVLAGSAAPPQEVTDEVLVEGHGWRILQP
MUL_3001|M.ulcerans_Agy99           ILNADDEPLRMSLPDLGIPHAEVLAGSAAPPQEVTDEVLVEGHGWRILQP
Mflv_3333|M.gilvum_PYR-GCK          ALNVADEPLPVALSGLGLGHAEIVAGSGAPPAEVVPDIVVPPHGWVILNP
Mvan_3059|M.vanbaalenii_PYR-1       ALNIDDDAMPVSLAEFGLARAEVVAGSGAPPAQVVADTVVPAHGWLILAP
Mb2498|M.bovis_AF2122/97            WLAAPDDALIFRRHGGGLVCALNAAERPLALPAGEPILASAPLTDATLPP
Rv2471|M.tuberculosis_H37Rv         WLAAPDDALIFRRHGGGLVCALNAAERPLALPAGEPILASAPLTDATLPP
MAB_1565c|M.abscessus_ATCC_199      WYGSPPGALAFRVKGGGLTCALNVSSDLVDLPEGEVILTSGPLVNGKLPR
                                                                                      

TH_2297|M.thermoresistible__bu      AR--------------
MSMEG_3576|M.smegmatis_MC2_155      R---------------
MLBr_02045|M.leprae_Br4923          ----------------
MAV_2842|M.avium_104                I---------------
MMAR_2753|M.marinum_M               A---------------
MUL_3001|M.ulcerans_Agy99           ASRFSCASVSGSSRRA
Mflv_3333|M.gilvum_PYR-GCK          R---------------
Mvan_3059|M.vanbaalenii_PYR-1       R---------------
Mb2498|M.bovis_AF2122/97            NAAAWLV---------
Rv2471|M.tuberculosis_H37Rv         NAAAWLV---------
MAB_1565c|M.abscessus_ATCC_199      NTAAWIV---------