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M. leprae Br4923 MLBr_02045 (-)

annotation: hypothetical protein MLBr_02045
coordinates: 2434923 - 2435180
length: 85

VSRIASQLGQPEHLTHALIILLTVAGVPSVYAGDEFGFRGLKEERYGVDDAVLPEFFSPPMQLDVFGVHA
WALHQYLIGLRRRHP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02045--100% (85)hypothetical protein MLBr_02045

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3333-4e-2460.00% (85) alpha amylase, catalytic region
M. tuberculosis H37Rv-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_2753treS_12e-3168.24% (85) trehalose synthase TreS_1
M. avium 104MAV_2842-4e-3475.29% (85) alpha-amylase 3
M. smegmatis MC2 155MSMEG_3576-3e-2463.53% (85) alpha-amylase 3
M. thermoresistible (build 8)TH_2297-4e-2253.93% (89) alpha-amylase 3
M. ulcerans Agy99MUL_3001treS_16e-3065.88% (85) trehalose synthase TreS_1
M. vanbaalenii PYR-1Mvan_3059-2e-2460.00% (85) alpha amylase, catalytic region

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_3576|M.smegmatis_MC2_155      MTMPDWVTHAIWWQIYPLGFVGAHP-ADP---PPGPEEHRLRRIVEWLDH
TH_2297|M.thermoresistible__bu      VTGPDWVRHTIWWQIYPLGFVGAHPWTDPTTGPPGPDEHRLRRVLDWLDH
Mflv_3333|M.gilvum_PYR-GCK          MSDPAWVEHVLWWQVYPLGFVGVHP-ADT---APEPGEHRLRRIVDWLDY
Mvan_3059|M.vanbaalenii_PYR-1       MTEPDWVDHVVWWQVYPLGFVGAYP-ADP---PPPPGEHRLRRIVDWLDY
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                MTGPDWVQHVIWWQVYPLGFVGAYPLPQSSE-PPQPEHHRLRRLVDWFDH
MMAR_2753|M.marinum_M               ------MQHAIWWQVYPLGFVGAFP---ANQ-PPDPGEHRLRRLVGWFDH
MUL_3001|M.ulcerans_Agy99           MSKPTWVQHAIWWQVYPLGFVGAFP---ANQ-PPNPGEHRLRRLVGWFDH
                                                                                      

MSMEG_3576|M.smegmatis_MC2_155      AVELGASGLALGPVFASRTHGYDTTDHLRIDPRLGDDADFDHVVAEAHRR
TH_2297|M.thermoresistible__bu      VVDLGASGLALGPVFASRSHGYDTTDHYRIDPRLGTDADFDELVEQAHRR
Mflv_3333|M.gilvum_PYR-GCK          AVELGASGVALGPVFHSRTHGYDTIDHYRVDPRLGDDSDFDHLIEESHSR
Mvan_3059|M.vanbaalenii_PYR-1       AIELGASGLALGPVFASRTHGYDTTDHYRIDPRLGEDGDFDHLVAEARDR
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                AIELGASGIALGPIFTSRTHGYDTTDHYRIDPRLGDDADFDHLIAQAHRR
MMAR_2753|M.marinum_M               AVELGASGVALGPIFDSRTHGYDTTDHFRIDPRLGDEGDFDHLVAEAHRR
MUL_3001|M.ulcerans_Agy99           AVELGASGVALGPIFDSRTHGYDTTDHFRIDPRLGDEGDFDHLVAEAHRR
                                                                                      

MSMEG_3576|M.smegmatis_MC2_155      GLRVLLDGVFNHVGTDFARYRQALGGDADSAA-WFRHRDGKFEVFEGHGE
TH_2297|M.thermoresistible__bu      GLRVLLDGVFHHVGTDFARYRDAAAG--GSSG-WFRRRGDRFETFEGHDE
Mflv_3333|M.gilvum_PYR-GCK          GLRVLLDGVFNHVGTEFPRYREAVDG--GDRS-WFATRGDDFATFEGHEG
Mvan_3059|M.vanbaalenii_PYR-1       GLRILLDGVFNHVGTDFPRYRDAAAG--GDSA-WFRRRGGDFATFEGHGD
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                GLRVLLDGVFNHVGVDFPRYRAAIDSDDHAAARWFRGSRGRFHTFEGHDG
MMAR_2753|M.marinum_M               GLRVLLDGVFNHVGMDFHRYRHAAD--DPSSAGWFRGRAGNFRTFEGHSE
MUL_3001|M.ulcerans_Agy99           GLRVLLDGVFNHVGVDFHSYRHAAD--DPSSAGWFRGRAGNFRTFEGHSG
                                                                                      

MSMEG_3576|M.smegmatis_MC2_155      LIALNHDNPEVVNYTAGVMRHWLGRGADGWRLDAAYAVPDRFWAQVLPIV
TH_2297|M.thermoresistible__bu      LIALDHDNPEVAAYTVDVLRHWLNRGADGWRLDAAYAVPDRFWARVLPDV
Mflv_3333|M.gilvum_PYR-GCK          LITLDHDNADVVDYTVDVMSHWLARGADGWRLDAAYAVPDRFWAQVLPRV
Mvan_3059|M.vanbaalenii_PYR-1       LIALDHRSAEVVDYTVDVMSHWLGRGADGWRLDAAYAVPDSFWAGVLPRV
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                LITLNHDNPEVVDYTVDVMAHWLGRGADGWRLDAAYAVPETFWAATLPRV
MMAR_2753|M.marinum_M               LITLNHANPEVADYVVDVMAHWLQRGADGWRLDAAYAVPQQFWAKVLPRV
MUL_3001|M.ulcerans_Agy99           LITLNHANPEVADYVVDVMAHWLQRGADGWRLDAAYAVPQQFWAKVLPRV
                                                                                      

MSMEG_3576|M.smegmatis_MC2_155      RSDFGDAWFVGEVIHGDYAATVAASTFDSVTQYELWKAVWSALNDGNFHE
TH_2297|M.thermoresistible__bu      RRSHPEAWFVGEVIHGDYAATVSAASFDSVTQYELWKAVWSSLNDGNFFE
Mflv_3333|M.gilvum_PYR-GCK          RQAHPAAWFVGEVIHGDYVARVRDSGFDSVTQYELWKAVWSSINDANFHE
Mvan_3059|M.vanbaalenii_PYR-1       RERHPQAWFVGEVIHGDYPARVRDSGFDSVTQYELWKAIWSSLNDGNFHE
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                RDRYPQAWFVGELIHGDYAAVVRAAGFDSATQYELWKAIWSSLNDGNFYE
MMAR_2753|M.marinum_M               RDRYPRAWFVGEIIHGDYAAAVQGAGFDSVTQYELWKAIWSGLNDGNFFE
MUL_3001|M.ulcerans_Agy99           RDRYPQAWFVGEIIHGDYAAAVQGAGFDSVTQYELWKAIWSGLNDGNFFE
                                                                                      

MSMEG_3576|M.smegmatis_MC2_155      LDWALQRHNDFLASFVPMTFVGNHDVTRIASQLSDARHLEHALVILFTTG
TH_2297|M.thermoresistible__bu      LDWALQRHNDFLAVFTPLTFIGNHDVTRIASRLADRRHVEHAVVLLLTVG
Mflv_3333|M.gilvum_PYR-GCK          LDWALTRHNEFLDTFVPLTFIGNHDVTRIASRLTDPAHVEHALVVLLTTG
Mvan_3059|M.vanbaalenii_PYR-1       LDWALTRHDEFLDTFVPMTFVGNHDVTRIASQLTDPTHVEHALVLLMTVG
MLBr_02045|M.leprae_Br4923          -------------------------MSRIASQLGQPEHLTHALIILLTVA
MAV_2842|M.avium_104                LDWALQRHNAFLGRFSPLTFIGNHDVTRIASQLNNPAHLAHALVLLLTVG
MMAR_2753|M.marinum_M               LDWALQRHNEFVASFAPLTFIGNHDVTRIASRLERPEHLAHALVILMTVG
MUL_3001|M.ulcerans_Agy99           LDWALQRHNEFVASFAPLTFIGNHDVTRIASRLERPEHLAHALVILMTVG
                                                             ::****:*    *: **:::*:*..

MSMEG_3576|M.smegmatis_MC2_155      GIPSVYAGDEWGHQGVKEERRGGDDAVRPEFGERP-----GPDAPGADVL
TH_2297|M.thermoresistible__bu      GVPSIYAGDEAGYLGVKEERFSGDDAIRPEFGSPPIVSGAGENTVAADLV
Mflv_3333|M.gilvum_PYR-GCK          GTPSVYAGDEVAYRGVKEERFGGDDAVRPEFRSPF----DGVGEQGHQMF
Mvan_3059|M.vanbaalenii_PYR-1       GTPSVYAGDEVAYRGVKEERFGGDDAVRPEFGSPF----EGVGEHGHQVF
MLBr_02045|M.leprae_Br4923          GVPSVYAGDEFGFRGLKEERYGVDDAVLPEFFSPP----MQLDVFGVHAW
MAV_2842|M.avium_104                GVPSVYAGDELGFRGVKEERFGGDDAVRPEFGSPP----IPLDDFGTEVW
MMAR_2753|M.marinum_M               GIPSIYAGDEFGWRAVKEERYGGDDAIRPEFGSPP----LQLTHDQASVW
MUL_3001|M.ulcerans_Agy99           GIPSIYAGDEFGWRAVKEERCGGDDAIRPEFGSPP----FELTHDQASVW
                                    * **:***** .  .:**** . ***: *** .                 

MSMEG_3576|M.smegmatis_MC2_155      RLHQYLIGLRRRHPWLHSATTTPLLLTNTQYVYRSAGAAGALVVALNLDD
TH_2297|M.thermoresistible__bu      RLHQHLIGLRRRNPWLHTATTAPLHLTNTQYVYESRSGEHALVVALNIDT
Mflv_3333|M.gilvum_PYR-GCK          RSHQHLIGLRRRHPWLHEARTTALSVTNTGYVYITRSGDDALVVALNVAD
Mvan_3059|M.vanbaalenii_PYR-1       RSHQHLIGLRRRNPWLHTARTTPLRVTNRGYVYTTRHGDDALVVALNIDD
MLBr_02045|M.leprae_Br4923          ALHQYLIGLRRRHP------------------------------------
MAV_2842|M.avium_104                RLHQYLIGLRRRHPWLHAATTTALLLQNRHYVYETRSGDEALLIVLNIGD
MMAR_2753|M.marinum_M               ALHQYLVGLRRRYPWLHTASTSALRLRNRQYVYQTRSADNALVVILNADD
MUL_3001|M.ulcerans_Agy99           ALHQYLVGLRRRYPWLHTASTSALRLRNRQYVYQTRSADNALVVILNADD
                                      **:*:***** *                                    

MSMEG_3576|M.smegmatis_MC2_155      APLRVALPELGLASGVVVAGSKAPPQEQIEVTEVPPHGWLVIEPR-----
TH_2297|M.thermoresistible__bu      APLPLRLSEIGLGAGRVVAGSGAPPAADLTNVDVAPHGWLIIEPAR----
Mflv_3333|M.gilvum_PYR-GCK          EPLPVALSGLGLGHAEIVAGSGAPPAEVVPDIVVPPHGWVILNPR-----
Mvan_3059|M.vanbaalenii_PYR-1       DAMPVSLAEFGLARAEVVAGSGAPPAQVVADTVVPAHGWLILAPR-----
MLBr_02045|M.leprae_Br4923          --------------------------------------------------
MAV_2842|M.avium_104                EPLRVSLDELGGRRGRVIGGSAAPPPEVLDTVVVEPQGWRILSPI-----
MMAR_2753|M.marinum_M               EPLRMSLPDLGIPRAEVLAGSAAPPQEVTDEVLVEGHGWRILQPA-----
MUL_3001|M.ulcerans_Agy99           EPLRMSLPDLGIPHAEVLAGSAAPPQEVTDEVLVEGHGWRILQPASRFSC
                                                                                      

MSMEG_3576|M.smegmatis_MC2_155      ----------
TH_2297|M.thermoresistible__bu      ----------
Mflv_3333|M.gilvum_PYR-GCK          ----------
Mvan_3059|M.vanbaalenii_PYR-1       ----------
MLBr_02045|M.leprae_Br4923          ----------
MAV_2842|M.avium_104                ----------
MMAR_2753|M.marinum_M               ----------
MUL_3001|M.ulcerans_Agy99           ASVSGSSRRA