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M. thermoresistible (build 8) TH_3948 (snm)

annotation: secretion protein Snm4
coordinates: 4146387 - 4147790
length: 468

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3948snm-100% (468)secretion protein Snm4
M. thermoresistible (build 8)TH_3996-7e-2327.10% (487) PUTATIVE -
M. thermoresistible (build 8)TH_2236-4e-2227.85% (517) PROBABLE CONSERVED TRANSMEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0298-1e-15662.37% (473) transmembrane protein
M. gilvum PYR-GCKMflv_0321-1e-16864.35% (474) hypothetical protein Mflv_0321
M. tuberculosis H37RvRv0290-1e-15662.37% (473) transmembrane protein
M. leprae Br4923MLBr_02529-1e-14859.24% (476) hypothetical protein MLBr_02529
M. abscessus ATCC 19977MAB_2226c-1e-14859.49% (469) hypothetical protein MAB_2226c
M. marinum MMMAR_0549-1e-15864.06% (473) transmembrane protein
M. avium 104MAV_4863-1e-15461.57% (484) hypothetical protein MAV_4863
M. smegmatis MC2 155MSMEG_0623snm0.071.79% (475) secretion protein Snm4
M. ulcerans Agy99MUL_1212-1e-15763.64% (473) transmembrane protein
M. vanbaalenii PYR-1Mvan_0420-1e-16263.42% (473) hypothetical protein Mvan_0420

CLUSTAL 2.0.9 multiple sequence alignment


TH_3948|M.thermoresistible__bu      ------MSDN-------TVMPIVRVAVLAAG-------DDGGRLTEMALP
MSMEG_0623|M.smegmatis_MC2_155      ------MSEN-------TVMPIVRVAVLAAG-------DDGGRLTEMALP
Mflv_0321|M.gilvum_PYR-GCK          ------MPQSALSDTN-TAMPIVRVAVLTATAGDEDG-DRAGRLTEIALP
Mvan_0420|M.vanbaalenii_PYR-1       ------MPPLDTNTLAGVVMPIVRVAVLTAAVGDEAAADRTGRITEIALP
Mb0298|M.bovis_AF2122/97            --------------MSGTVMQIVRVAILADS-----------RLTEMALP
Rv0290|M.tuberculosis_H37Rv         --------------MSGTVMQIVRVAILADS-----------RLTEMALP
MMAR_0549|M.marinum_M               --------------MSGTVMPIVRVAILADS-----------RLTEVALP
MUL_1212|M.ulcerans_Agy99           --------------MSGTVMPIVRVAILADS-----------RLTEVALP
MAV_4863|M.avium_104                -------------MTSGTVMPIVRVAILADS-----------RLTEMALP
MLBr_02529|M.leprae_Br4923          MVYVFAEEFCEGPVTSGAVMPIVRVAILADS-----------RLIEMALP
MAB_2226c|M.abscessus_ATCC_199      -------------MSDNAVMPIVRVAVLGEE-----------KLTEVALP
                                                     ..* *****:*              :: *:***

TH_3948|M.thermoresistible__bu      AELPLREILPAVQQMAAPTEDG------------ADVPDAVRLSLAPIGG
MSMEG_0623|M.smegmatis_MC2_155      SELPLREILPAVQRIVQPARENDGAA------DPAAAPNPVRLSLAPIGG
Mflv_0321|M.gilvum_PYR-GCK          AQLPLREIIPAVQRIVAPSDDAPG---------------TDPVSLAPIGG
Mvan_0420|M.vanbaalenii_PYR-1       ADLPLREIVPAVQRIVAPSDDSAGG--------------AEQLSLAPIGG
Mb0298|M.bovis_AF2122/97            AELPLREILPAVQRLVVPSAQNGDG-------GQADSGAAVQLSLAPVGG
Rv0290|M.tuberculosis_H37Rv         AELPLREILPAVQRLVVPSAQNGDG-------GQADSGAAVQLSLAPVGG
MMAR_0549|M.marinum_M               AELPLREILPAVQRLVIPVAEDGDA-------GSADLGIAGHLSLAPVGG
MUL_1212|M.ulcerans_Agy99           AELPLREILPAVQRLVIPVAEDGDA-------GSADLGIAGHLSLAPVGG
MAV_4863|M.avium_104                AELPLREILPAVQRLVVPAAANGDSEDGAPSRGAAEVGGAVQLSLAPIGG
MLBr_02529|M.leprae_Br4923          TELPLREILPAVKRLVVPAASDNDS--------PLAANASLHLSLAPIGG
MAB_2226c|M.abscessus_ATCC_199      TQLPMRDIIPAVHRMVAPDATEATT--------------PQRLSLAPVNG
                                    ::**:*:*:***:::. *                     .  :****:.*

TH_3948|M.thermoresistible__bu      APFSLDATLQTVGVVDGDLLALQPIPSGPPAPRIVEDIADAAVIFSAART
MSMEG_0623|M.smegmatis_MC2_155      APFSLDATLDTVGVVDGDLLALQAVPSGPPAPRIVEDIADAAVIFSEARR
Mflv_0321|M.gilvum_PYR-GCK          APYSLDATLTTVGVVDGDLLALQPIPAGPPAPRIVEDIADAAMIFSAARE
Mvan_0420|M.vanbaalenii_PYR-1       APFSLDATLNTVGVVDGDLLALQPVPAGPPAPRIVEDIADAAMIFSASRE
Mb0298|M.bovis_AF2122/97            QPFSLDASLDTVGVVDGDLLVLQPVPAGPAAPGIVEDIADAAMIFSTSRL
Rv0290|M.tuberculosis_H37Rv         QPFSLDASLDTVGVVDGDLLVLQPVPAGPAAPGIVEDIADAAMIFSTSRL
MMAR_0549|M.marinum_M               APFSLDASLDTVGVVDGDLLVLQPVPTGPAAPGIVEDIADAAMIFSTSRL
MUL_1212|M.ulcerans_Agy99           APFSLDASLDTVGVVDGDLLVLQPVPTGPAAPGIVEDIADAAMIFSTSRL
MAV_4863|M.avium_104                APFSLDASLDTVGVVDGDLLALQPVPAGPAAPGIVEDIADAAMIFSTSRL
MLBr_02529|M.leprae_Br4923          APFSLDASLDTVGVVDGDLLALQPVPVGPAAPGIVEDIADAAMIFSTARL
MAB_2226c|M.abscessus_ATCC_199      APFSADATLDTVGVVDGDLLTLRPTPAGPAAPGIVEDIADAAVIFSESRK
                                     *:* **:* **********.*:. * **.** *********:*** :* 

TH_3948|M.thermoresistible__bu      RPWSPAHIARAAAVALIGLILAASALSVAHRILTGDVLGLFVVSGVAVAT
MSMEG_0623|M.smegmatis_MC2_155      RQWGPTHIARGAALALIGLILVGTGLSVAHRVITGDLLGQFIVSGIALAT
Mflv_0321|M.gilvum_PYR-GCK          KPWGTPQIQRGATVAVVGLMLVATALAVAHRVVTDSIIGVFAVSAVAIAA
Mvan_0420|M.vanbaalenii_PYR-1       KPWGVANIRSGATAAVIGLTVVATALAVAHRVFTDSLIGLFAVSAVAIGA
Mb0298|M.bovis_AF2122/97            KPWGIAHIQRGALAAVIAVALLATGLTVTYRVATGVLAGLLAVAGIAVAS
Rv0290|M.tuberculosis_H37Rv         KPWGIAHIQRGALAAVIAVALLATGLTVTYRVATGVLAGLLAVAGIAVAS
MMAR_0549|M.marinum_M               RPWDARHLQRGALAALIGVALAGSGLAVAYRAATGALAGLLIVSVIAVAM
MUL_1212|M.ulcerans_Agy99           RPWDARHLQRGALAALIGVALAGSGLAVAYRVATGALAGLLIVSVIAVAM
MAV_4863|M.avium_104                RPWGTTHIQRFALATVIAVALLATGLSVSYRVATGALAGLVAVSAVAALT
MLBr_02529|M.leprae_Br4923          QSWGPTHIRRGALAATTAVTFAATGLGVTYRAVTGALTGLLVVIVIAVLI
MAB_2226c|M.abscessus_ATCC_199      RPWGAEHIARVGRFGVLGLIAAATILAIVHSIRTGSSLSLAGLAVVAVAA
                                    : *.  ::   .     .:   .: * : :   *.   .   :  :*   

TH_3948|M.thermoresistible__bu      VLAALLARPRSIPLAAALSVAALVPVGAAFALAVPGDFGAPHLLLAAAGV
MSMEG_0623|M.smegmatis_MC2_155      VIAALAVRNRSAVLATSLAVTALVPVAAAFALGVPGDFGAPNVLLAAAGV
Mflv_0321|M.gilvum_PYR-GCK          VLGALVARTGSPRVATALAAAALPSVGAAFTLAVPGDFGASAVLLGAAGI
Mvan_0420|M.vanbaalenii_PYR-1       VLGALLARASSPRLATALAAAALPSVAAAFTLAVPGDFGASNIVLGAAGV
Mb0298|M.bovis_AF2122/97            ALAGLLITIRSPRSGIALSIAALVPIGAALALAVPGKFGPAQVLLGAAGV
Rv0290|M.tuberculosis_H37Rv         ALAGLLITIRSPRSGIALSIAALVPIGAALALAVPGKFGPAQVLLGAAGV
MMAR_0549|M.marinum_M               ALAGLLLGARSPRTGIALSIAALAPVGAALALAVPGSFGAAQVLLAAAGV
MUL_1212|M.ulcerans_Agy99           ALAGLLLGARSPRTGIALSIAALAPVGAALALAVPGSFGAAQVLLAAAGV
MAV_4863|M.avium_104                AIVGLLATARSPRNGMALSIAALVPIGAALALAVPGRFGPAQVMLAAAGV
MLBr_02529|M.leprae_Br4923          ALGGLVLRSRAARTGLVLSIAALVPIGAVFALAVPGIFGPAQVLLASAGV
MAB_2226c|M.abscessus_ATCC_199      AIGALVAHVRSARLGAELAVAALVPIAGALALAVPGSGLAPRVLLGAAGV
                                    .: .*     :   .  *: :** .:...::*.***   .. ::*.:**:

TH_3948|M.thermoresistible__bu      TAWSIISIT--VAERS--VAVFTTASVLGVATMAAAAAATLWEPSWVVLG
MSMEG_0623|M.smegmatis_MC2_155      AAWSLISMAGSPDDRG--IAVFTATAVTGVGVLLVAGAASLWVISSDVIG
Mflv_0321|M.gilvum_PYR-GCK          AAWSIISIT--VGERA--IAVFTAVAAAALGVAVAAAAATVWSLSLLDIG
Mvan_0420|M.vanbaalenii_PYR-1       AAWSVISIT--VGERA--IALFTAAAASALGVLLVSAVASVWTLTPVHVG
Mb0298|M.bovis_AF2122/97            AAWSLIALMIPSAERERVVAFFTAAAVVGASVALAAGAQLLWQLPLLSIG
Rv0290|M.tuberculosis_H37Rv         AAWSLIALMIPSAERERVVAFFTAAAVVGASVALAAGAQLLWQLPLLSIG
MMAR_0549|M.marinum_M               TAWSLICLMVPGEQRERIVALFTAVAVVGAALLLAAGAELLWQLPVSSIG
MUL_1212|M.ulcerans_Agy99           TAWSLICLMVPGEQRERIVALFTAVAVVGAALLLAAGVELLWQLPVSSIG
MAV_4863|M.avium_104                TAWSLIALMAPSAERERLAGFFTATAVLGAAVLLAAGAELLWHITPVALG
MLBr_02529|M.leprae_Br4923          TAWSLIALIVPGPERVRIVAFFTATVVIGVAVMLEAGAALLWQLTPLTIG
MAB_2226c|M.abscessus_ATCC_199      AAWSLIYLIV----ARQLIAFFTATTVLSLGIAGAAGAHVLWHPSLLVVG
                                    :***:* :           ..**:. . . .    :..  :*  .   :*

TH_3948|M.thermoresistible__bu      CGLIVLGLLVTVQAAQLSAMFARFPLPVIPAPGDPTPSAQPLRVLEDLPR
MSMEG_0623|M.smegmatis_MC2_155      CALVLLGLIVTVQAAQLSAMWARFPLPVIPAPGDPTPAARPLSVLADLPR
Mflv_0321|M.gilvum_PYR-GCK          CVLILIALLITVQAAQLSAMCARLPVPVIPAPGDPAPSALPRRVLEDLPR
Mvan_0420|M.vanbaalenii_PYR-1       CILILAGLVVTVQAAQLSAMCARLPVPVIPAPGDPTPSAPPLRVLEDLPR
Mb0298|M.bovis_AF2122/97            CGLIVAALLVTIQAAQLSALWARFPLPVIPAPGDPTPSAPPLRLLEDLPR
Rv0290|M.tuberculosis_H37Rv         CGLIVAALLVTIQAAQLSALWARFPLPVIPAPGDPTPSAPPLRLLEDLPR
MMAR_0549|M.marinum_M               CGLIVAALLVTIQAAQLSAVWARFPLPVIPAPGDPTPSAPSLRVLEDLPR
MUL_1212|M.ulcerans_Agy99           CGLIVAALLVTIQAAQLSAVWARFPLPVIPAPGDPTPSAPSLRVLEDLPR
MAV_4863|M.avium_104                CGLIVAALLVTVEAAPLSALWARFPLPVIPAPGDPTPSAPPLPVLEDLPR
MLBr_02529|M.leprae_Br4923          CGLILAALLVTVEAAQLSALWARFPLPVIPAPGDPTPSAPSFQVLEDLPR
MAB_2226c|M.abscessus_ATCC_199      CGLIIVALLVTVRAAQLSAFAARFPLPTIPAPGDATPSAPAMSVLKDLPR
                                    * *:: .*::*:.** ***. **:*:*.******.:*:* .  :* ****

TH_3948|M.thermoresistible__bu      RVRVGDSHQTGLIAAGVLLSVAGSVALVAP-----PGASGWAWYVVVAAA
MSMEG_0623|M.smegmatis_MC2_155      RVRVSQAHQTGVIAAGVLLGVAGSVALVSS-----ANASPWAWYIVVAAA
Mflv_0321|M.gilvum_PYR-GCK          RIRAGDAYQTGFIAAGVLLAVTGSVLVVWPAVSGDGGVPVWSWYLVAATA
Mvan_0420|M.vanbaalenii_PYR-1       RIRASDAHQTGFIAAGVLLGVAGSVFAVWPGVGGDGSASPWAWLLVGATA
Mb0298|M.bovis_AF2122/97            RVRVSDAHQSGFIAAAVLLSVLGSVAIAVR----PEALSVVGWYLVAATA
Rv0290|M.tuberculosis_H37Rv         RVRVSDAHQSGFIAAAVLLSVLGSVAIAVR----PEALSVVGWYLVAATA
MMAR_0549|M.marinum_M               RVRVSDAHQSGFIAAAVLLSVLGSVAIALR----PDTVSALGWYVVAATA
MUL_1212|M.ulcerans_Agy99           RVRVSDAHQSGFIAAAVLLSVLGSVAIALR----PDTVSALGWYVVAATA
MAV_4863|M.avium_104                RVRIGDAHQSGFIAAAVLLSALGSVAIALR----PETLSAAGWYVVGATA
MLBr_02529|M.leprae_Br4923          RVRISSAHQSGFIAAATLLSMLGSVAIALR----PEAVSSVGWYLVAATA
MAB_2226c|M.abscessus_ATCC_199      RVQLSDSHQSGFIAGASILAILGSLAVVGG----AAPASPWAWYLVAAVS
                                    *:: ..::*:*.**.. :*.  **:  .          .  .* :* *.:

TH_3948|M.thermoresistible__bu      AGSTLRARVWDAASCKLWLLSHSYLITVALLIGFTVTERYPAAWLALAVL
MSMEG_0623|M.smegmatis_MC2_155      AGAALRARVWDSAACKAWLLGHSYLLAVALLVAFVIGDRYQAALWALAAL
Mflv_0321|M.gilvum_PYR-GCK          LAAALRARVWDSSACKAWLLGHGYLVTTVLLVLSAAHEKYSAAWWALGVL
Mvan_0420|M.vanbaalenii_PYR-1       LGAVLRARVWDSASCKAWLLAQPFLMSAVLLGIFAVTGRYDAAWWTLGAF
Mb0298|M.bovis_AF2122/97            AAATLRARVWDSAACKAWLLAQPYLVAGVLLVFYTTTGRYVAAFGAVLVL
Rv0290|M.tuberculosis_H37Rv         AAATLRARVWDSAACKAWLLAQPYLVAGVLLVFYTATGRYVAAFGAVLVL
MMAR_0549|M.marinum_M               ATATLRARIWDSAACKAWLLTQPYLVGGTLLVLYAATGHFIAAFGALVVL
MUL_1212|M.ulcerans_Agy99           ATATLRARIWDSAACKAWLLTQPYLVGGTLLVLYAATGHFIAAFGALVVL
MAV_4863|M.avium_104                ATSVLRARVWDSAACKAWLLAQPYLAAGVLLVLYTATGRYAGALGAVLVL
MLBr_02529|M.leprae_Br4923          VAATLRARVWDSVACKAWLLAQPYLVASVLLGLYTATGRYVAASAALLVL
MAB_2226c|M.abscessus_ATCC_199      AGAALRARVWDSAVCKAWLLAVPFLVSTALLVIFAVEDRYTGALVALGVL
                                      :.****:**:  ** ***   :*   .**   .   :: .*  :: .:

TH_3948|M.thermoresistible__bu      ALLVTVWAVVVAYPRIASPDSYSLPMRRLTGFLATALDASLIPVMAYLVG
MSMEG_0623|M.smegmatis_MC2_155      AVLVLVWIVAALNPKIASPDTYSLPMRRMVGFLATGLDASLIPVMALLVG
Mflv_0321|M.gilvum_PYR-GCK          AVLVAAWAVAALNPRIAQPDTYSLPMRRVVGFVATALDASVIPVMAYLVG
Mvan_0420|M.vanbaalenii_PYR-1       AVLAAAWVVAALNPRIAEPQTYSLPMRRLLGFVAAAVDASVIPVMAYLVG
Mb0298|M.bovis_AF2122/97            AVLMLAWVVVALNPGIASPESYSLPLRRLLGLVAAGLDVSLIPVMAYLVG
Rv0290|M.tuberculosis_H37Rv         AVLMLAWVVVALNPGIASPESYSLPLRRLLGLVAAGLDVSLIPVMAYLVG
MMAR_0549|M.marinum_M               AVLAVAWVVVALNPVIASPESYSLPLRRLLGFLAAGLDASLIPVMAYLVG
MUL_1212|M.ulcerans_Agy99           AVLAVAWVVVALNPVIASPESYSLPLRRLLGFLAAGLDASLIPVMAYLAG
MAV_4863|M.avium_104                LALVAVWIVVALNPGIAAPESYSLPVRRLVGFVATGLDASLIPVMAFVVG
MLBr_02529|M.leprae_Br4923          VVVVLAWAVVALNPRIASSDSYSLPLRRLLGMVASGLDASLIPAMAYLVS
MAB_2226c|M.abscessus_ATCC_199      ALLVAAVAVVVFNPKIGEAESYSLPSRRLLGFLASGIDASLLPVIAYLTG
                                      :  .  *..  * *. .::**** **: *::*:.:*.*::*.:* :..

TH_3948|M.thermoresistible__bu      LFSWVLNR-
MSMEG_0623|M.smegmatis_MC2_155      LFSLVLDR-
Mflv_0321|M.gilvum_PYR-GCK          LFTLVLNGF
Mvan_0420|M.vanbaalenii_PYR-1       LFAWALNGV
Mb0298|M.bovis_AF2122/97            LFAWVLNR-
Rv0290|M.tuberculosis_H37Rv         LFAWVLNR-
MMAR_0549|M.marinum_M               LFTWVLNR-
MUL_1212|M.ulcerans_Agy99           LFTWVLNR-
MAV_4863|M.avium_104                LFGWVLDR-
MLBr_02529|M.leprae_Br4923          LFSWVLNR-
MAB_2226c|M.abscessus_ATCC_199      LFSWILNR-
                                    **   *: