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MPNRGGFVHAARERAGLTCRELAEKAGCSLRYVHDIEQGCSPSIRVLNGLVRALQLSAWEQRFLFAACGR ILPDPALTDTDISQRYLDALQPHPAAALHPSWRFKAWNQQWQRLFQGVLLAPSMHQWLYLSTTSRRILRN WDEVSQWCVGWLRYGLAVDVDAVKPMVSALMPVTEFRREWEAQVIPVDPATRLWVVRDGGTELRIDMRFW HASPMPGGLLLGVILDAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3947 | - | - | 100% (228) | transcriptional regulatory protein |
| M. marinum M | MMAR_0799 | - | 2e-06 | 34.83% (89) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0484 | - | 3e-07 | 33.01% (103) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_5170 | - | 2e-11 | 30.77% (182) | XRE family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0474 | - | 3e-07 | 33.01% (103) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4084c | - | 2e-08 | 38.30% (94) | transcriptional regulator |
| M. avium 104 | MAV_4676 | - | 9e-08 | 37.08% (89) | transcriptional regulator, XRE family protein |
| M. smegmatis MC2 155 | MSMEG_1289 | - | 4e-13 | 29.47% (207) | hypothetical protein MSMEG_1289 |
| M. thermoresistible (build 8) | TH_0868 | - | 6e-08 | 37.23% (94) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_4542 | - | 1e-06 | 34.83% (89) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1162 | - | 3e-12 | 34.04% (141) | XRE family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0484|M.bovis_AF2122/97 MSSEEKLAAKVSTKASDVAS-----DIGSFIRSQRETAHVSMRQLAERSG
Rv0474|M.tuberculosis_H37Rv MSSEEKLAAKVSTKASDVAS-----DIGSFIRSQRETAHVSMRQLAERSG
MUL_4542|M.ulcerans_Agy99 MPGEEKLGAKVS-AVSSKAS-----DIGSFIRTQRENAHVSMRQLAERSG
MAV_4676|M.avium_104 MAPEEKLSAKVSNAASDMAS-----DIGSFIRSQRELAQVSVRQLAEKSG
TH_0868|M.thermoresistible__bu --------------VSNAAQ-----DIGSFIRSQREAAQVSLRQLAEKAG
MAB_4084c|M.abscessus_ATCC_199 MPQE----SDLATAVSNAAS-----DIGGFIRAQREAAQVSVRQLAEKAG
Mflv_5170|M.gilvum_PYR-GCK MDTRAQRRLALGEFLRARREAIRRADVGLPELPRARTGGLRREEVAVTAG
Mvan_1162|M.vanbaalenii_PYR-1 MDRRAQQRLALGEFLRARRRAAVRAELGLPDMPRSRTSGLRREEVAVQAG
MSMEG_1289|M.smegmatis_MC2_155 MATQEEHRAELGAFLRASRERLNRAEFGLPPAGRNRTVGLRREEVSYLSG
MMAR_3947|M.marinum_M -----------------------MPNRGGFVHAARERAGLTCRELAEKAG
: * . : .::: :*
Mb0484|M.bovis_AF2122/97 VSNPYLSQVERGLRK-PSADVLSQIAKALRVS------------------
Rv0474|M.tuberculosis_H37Rv VSNPYLSQVERGLRK-PSADVLSQIAKALRVS------------------
MUL_4542|M.ulcerans_Agy99 VSNPYLSQVERGLRK-PSADVLAQIAKALRVS------------------
MAV_4676|M.avium_104 VSNPYLSQVERGLRK-PSADVLNQIAKALRVS------------------
TH_0868|M.thermoresistible__bu VSNPYLSQIERGLRK-PSADVLNQIAKALRVS------------------
MAB_4084c|M.abscessus_ATCC_199 VSNPYLSQIERGLRR-PSAEVLNQIAKALRVS------------------
Mflv_5170|M.gilvum_PYR-GCK VSVTWYTWLEQGRDINPSKQVLDAVADALRLSPAEHEYVLALGGYAVDAA
Mvan_1162|M.vanbaalenii_PYR-1 VSVTWYTWLEQGRDINPSRQVLDAIARALRLSPSEHDYVLALGGYTVDHA
MSMEG_1289|M.smegmatis_MC2_155 VSVTWYTWLEQGRDINPSRQVLDAVSRTLRLSAAQHRYVLTLAGFAPVSA
MMAR_3947|M.marinum_M CSLRYVHDIEQGCSP--SIRVLNGLVRALQLSAWEQRFLFAACGRILPDP
* : :*:* * ** : :*::*
Mb0484|M.bovis_AF2122/97 ----------------------------------------AEVLYVRAGI
Rv0474|M.tuberculosis_H37Rv ----------------------------------------AEVLYVRAGI
MUL_4542|M.ulcerans_Agy99 ----------------------------------------AEVLYVRAGI
MAV_4676|M.avium_104 ----------------------------------------AEVLYVRAGI
TH_0868|M.thermoresistible__bu ----------------------------------------AEVLYVRAGI
MAB_4084c|M.abscessus_ATCC_199 ----------------------------------------AEVLYVRAGI
Mflv_5170|M.gilvum_PYR-GCK VSRGPL---PPHIQHFLDALEGYPAFAITPDWGIAAWNTTYAALYPNVER
Mvan_1162|M.vanbaalenii_PYR-1 VTAGPP---PPQIQRFLDALGGHPAFAITSDWGIAAWNTAYAALYPNIER
MSMEG_1289|M.smegmatis_MC2_155 APADDVTDVPGHVQRLLDAIGDNPAYALTPEWGIAGWNAAYQRLYPNVAT
MMAR_3947|M.marinum_M ALTDTD---------------------ISQRYLDALQPHPAAALHPSWRF
*:
Mb0484|M.bovis_AF2122/97 LEP-SETSQVRDAIITDTAITERQ-------KQILLDIYASFTHQN-EAT
Rv0474|M.tuberculosis_H37Rv LEP-SETSQVRDAIITDTAITERQ-------KQILLDIYASFTHQN-EAT
MUL_4542|M.ulcerans_Agy99 LEP-SETSQVRDVIITDTAITERQ-------KQILLDIYASFTQQN-EAV
MAV_4676|M.avium_104 LEP-SDKSQVRDAIVTDTAITERQ-------KQILLDIYASFTQQN-EAT
TH_0868|M.thermoresistible__bu LEP-GEPSEVRDAIVNDTAITERQ-------KQVLLDIYTSFCRQN-EQD
MAB_4084c|M.abscessus_ATCC_199 LDR-SDASPVRDAIIADTFITERQ-------KQVLLDVYSSFVQQNAEAQ
Mflv_5170|M.gilvum_PYR-GCK VPE-TDRN-LLWLVFTDPYIHELLPNWDTDSRRFLAEFRADAGPRVGEPS
Mvan_1162|M.vanbaalenii_PYR-1 VPP-PDRN-LLWLVFMDPAIRELLPDWDADSRRFLAEFRADAGPMVGEPS
MSMEG_1289|M.smegmatis_MC2_155 TPP-AERN-LLWAVFTDPFVRDLLDDWPVTSQRFLAEFRAEIGPRLGNPT
MMAR_3947|M.marinum_M KAWNQQWQRLFQGVLLAPSMHQWLYLS--TTSRRILRNWDEVSQWCVGWL
: . : :. . : : : : .
Mb0484|M.bovis_AF2122/97 REECPSDPTPTDD-------------------------------------
Rv0474|M.tuberculosis_H37Rv REECPSDPTPTDD-------------------------------------
MUL_4542|M.ulcerans_Agy99 CEEYSS-PSEIDD-------------------------------------
MAV_4676|M.avium_104 HEECPTQPDSE---------------------------------------
TH_0868|M.thermoresistible__bu ADADEEQPTASRD-------------------------------------
MAB_4084c|M.abscessus_ATCC_199 SDVAESDLELPATTE-----------------------------------
Mflv_5170|M.gilvum_PYR-GCK YTALVSRLSSESPHFAAAWQATSIERFTSRERLFRHPAAGELRLEHHQVA
Mvan_1162|M.vanbaalenii_PYR-1 YTALVSRLSSESPHFATAWRAADIERFTSRERLFRHPVVGELRLEHHQVA
MSMEG_1289|M.smegmatis_MC2_155 LLGLIERLSEASDEFRAGWERHDIRGFESRERVFHHPEFGVVTYEHHQLR
MMAR_3947|M.marinum_M RYGLAVDVDAVKPMVSALMPVTEFRREWEAQVIPVDPATRLWVVRDG--G
Mb0484|M.bovis_AF2122/97 ------------------------------------
Rv0474|M.tuberculosis_H37Rv ------------------------------------
MUL_4542|M.ulcerans_Agy99 ------------------------------------
MAV_4676|M.avium_104 ------------------------------------
TH_0868|M.thermoresistible__bu ------------------------------------
MAB_4084c|M.abscessus_ATCC_199 ------------------------------------
Mflv_5170|M.gilvum_PYR-GCK PVDVPDIQIVAYLPVPDSVASERLRMLTGQA-DTAR
Mvan_1162|M.vanbaalenii_PYR-1 PVDVPDIQIVAYLPEPGSVAAERLRRLVGQAGDTAR
MSMEG_1289|M.smegmatis_MC2_155 PSDQPELQLVVYTPTHRNP-----------------
MMAR_3947|M.marinum_M TELRIDMRFWHASPMPGGLLLGVILDAG--------