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M. thermoresistible (build 8) TH_1451 (-)

annotation: amidohydrolase family protein
coordinates: 2755281 - 2756138
length: 286

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1451--100% (286)amidohydrolase family protein
M. thermoresistible (build 8)TH_1218-4e-0927.83% (212) amidohydrolase family protein
M. thermoresistible (build 8)TH_4033-4e-0726.90% (145) PUTATIVE amidohydrolase 2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3540c-3e-0724.88% (209) hypothetical protein Mb3540c
M. gilvum PYR-GCKMflv_1007-1e-10965.37% (283) amidohydrolase 2
M. tuberculosis H37RvRv3510c-3e-0724.88% (209) hypothetical protein Rv3510c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4667-1e-12370.18% (285) putative amidohydrolase
M. marinum MMMAR_4998-3e-0726.80% (153) hypothetical protein MMAR_4998
M. avium 104MAV_0646-4e-0826.25% (259) amidohydrolase family protein
M. smegmatis MC2 155MSMEG_0628-1e-12672.98% (285) amidohydrolase family protein
M. ulcerans Agy99MUL_3876-3e-0627.85% (158) metal-dependent hydrolase
M. vanbaalenii PYR-1Mvan_0424-1e-12470.92% (282) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


TH_1451|M.thermoresistible__bu      -----------------VRELWRGLGLPGLIDVHTHFMPKRVMDKVWRYF
MSMEG_0628|M.smegmatis_MC2_155      ------MMDE----IAAVRSIWSDLGLPGLIDVHTHFMPKNVMDKVWQYF
Mvan_0424|M.vanbaalenii_PYR-1       -------MDE----PESARRIWQALELPGIVDVHTHFMPKNVMDKVWRYF
MAB_4667|M.abscessus_ATCC_1997      -------MSESAFDPAPVRQIWQELGIPGIVDVHTHFMPKSVMDKVWAYF
Mflv_1007|M.gilvum_PYR-GCK          MCDDHGSSTVPHDEPERIRSLREDLGLDAIVDVHTHFMPKRVMDKVWAYF
Mb3540c|M.bovis_AF2122/97           ------------------MTIDVWMQHP-----TQRFLHGDMFASLRRWT
Rv3510c|M.tuberculosis_H37Rv        ------------------MTIDVWMQHP-----TQRFLHGDMFASLRRWT
MAV_0646|M.avium_104                ------------------MTIDVWMQHP-----TVRFLRSDMLASLRRWT
MMAR_4998|M.marinum_M               ------------------MTIDAWMQHP-----TQRFLRSDMLASLRRWT
MUL_3876|M.ulcerans_Agy99           ---------------MTDRAIDCLVNVHFG---EAEAQPNWMLKVRDDYF
                                                        :   :          .     ::     : 

TH_1451|M.thermoresistible__bu      DSAGPLVGREWPISYRLAETERVEVLRGFGVTRFTSLVYPHKPDMAAWLN
MSMEG_0628|M.smegmatis_MC2_155      DSQGPLIGREWPITYRADEQQRLATLREFGVRRFSSLVYPHKPDMAAWLN
Mvan_0424|M.vanbaalenii_PYR-1       DDAGPLVGRPWPITYRSDENARLHTLRSFGVLAFTSLIYAHKPDMAAWLN
MAB_4667|M.abscessus_ATCC_1997      DSAGPLVGRPWPITYRADESQRVTTLRDFGVLRFTSLVYPHKPQMAAWLN
Mflv_1007|M.gilvum_PYR-GCK          DSAGPLTGRPWPISYRQDEQTRVAGLREFGVSAFTSLVYPHKPDMAAWLN
Mb3540c|M.bovis_AF2122/97           GGSIPETDIPIEATVSSMDAGGVTLGLLSAWRGPNGQDLISNDAVAEWVR
Rv3510c|M.tuberculosis_H37Rv        GGSIPETDIPIEATVSSMDAGGVTLGLLSAWRGPNGQDLISNDAVAEWVR
MAV_0646|M.avium_104                GGSIPDTDIPIEATLASMDAAGVGYGLLSAWRGPNGQDLVSNDEVAQWVA
MMAR_4998|M.marinum_M               DSSIPEAQIPIEATIASMDAADVEFGLLSAWRGPNGQDLVSNDEVAGWVD
MUL_3876|M.ulcerans_Agy99           KGP-DSMFAPVDLAQLLDEMDEQGVQRAILMDSLASPSLTACKFVQAKPD
                                     .           :    :                .        :     

TH_1451|M.thermoresistible__bu      QWAAEFARTTPDCLATATFYPEPGVAEYVTRAIDDG-VRVFKVHVQVGG-
MSMEG_0628|M.smegmatis_MC2_155      QWAREFARNTPDCLSTATFYPEEQAGRYVAEAIDAG-TQIFKAHIQVGA-
Mvan_0424|M.vanbaalenii_PYR-1       QWAAGFAADTPDCMATATFYPEPGAAGYVSAAIESG-TRVFKAHVQVGD-
MAB_4667|M.abscessus_ATCC_1997      QWAAQFAAQTPDCIHTATFFPEPGAADYVREAIDAG-VGVFKVHVQVGA-
Mflv_1007|M.gilvum_PYR-GCK          EWATGFARATPDCLHTATFYPERGAAGYVQRAIDAG-ARVFKAHIQVGD-
Mb3540c|M.bovis_AF2122/97           LYPNRFAG-----LAAVDLDRPMAAVRELRRRVGEG-FVGLRVVPWLWG-
Rv3510c|M.tuberculosis_H37Rv        LYPNRFAG-----LAAVDLDRPMAAVRELRRRVGEG-FVGLRVVPWLWG-
MAV_0646|M.avium_104                AHPNRFAG-----LAAVDLDRPMEAVRELRCRIADGGFVGLRVVPWLWN-
MMAR_4998|M.marinum_M               LHPQRFAG-----LAAVDLDRPMVAVRELRSRIASG-FVGLRVVPWLWE-
MUL_3876|M.ulcerans_Agy99           RFALAMGG--------INLLRPVRPLRELTAIVGELPVAYAAVGPSFWGE
                                      .  :.           :         :   :         .   .   

TH_1451|M.thermoresistible__bu      --YDPTDPLLDDVWGVIEDAGVPVVIHCG-SGPAPGEFTG-PEP-VRSLL
MSMEG_0628|M.smegmatis_MC2_155      --YDPNDPLLDEVWGMVEDAAVPVVIHCG-SGPAPGEYTG-PER-VEKLL
Mvan_0424|M.vanbaalenii_PYR-1       --YDPTDPLLDDVWGLIEDAGTPVVIHCG-SGPAPGRYTG-PAP-IRAVL
MAB_4667|M.abscessus_ATCC_1997      --FSPTDPLLVPVWGLIEDAGVPVVIHCG-SGPAPGEFTG-PDP-VTALL
Mflv_1007|M.gilvum_PYR-GCK          --YSPADPLLGEVWDILEHHRVPTVIHAG-SGPAPGRFTG-PAP-VAEIL
Mb3540c|M.bovis_AF2122/97           --APPTDRRYYPLFAECVQSAVPFCTQVGHTGPLRPSETGRPIPYIDQVA
Rv3510c|M.tuberculosis_H37Rv        --APPTDRRYYPLFAECVQSAVPFCTQVGHTGPLRPSETGRPIPYIDQVA
MAV_0646|M.avium_104                --APPTDRRYYPLFAACVEAGVPFCTQVGHTGPLRPSETGRPIPYIDQVA
MMAR_4998|M.marinum_M               --APPTDRRYYPLFAECVESGVPFCTQVGHTGPLRPSETGRPIPYIDQVA
MUL_3876|M.ulcerans_Agy99           GQYPPSDAVYYPLYVKCAELELALCINTGIPGPPIPGEVQHPMH-LDRVC
                                        * *     ::    .   .   : * .**     .  *   :  : 

TH_1451|M.thermoresistible__bu      GRHPRLRLIIAHMGMPEYVDFIDLAERFDGVRLDTTMAFTDFAEKVMPFP
MSMEG_0628|M.smegmatis_MC2_155      ARHPRLVLIIAHMGMPEYSEFLDLAERFDGVRLDTTMAFTPFSEAMMPFP
Mvan_0424|M.vanbaalenii_PYR-1       AEHPRLRLVIAHMGGPEYSEFLDLCRDFEQLHLDTTMAFTGFTEKNMPFP
MAB_4667|M.abscessus_ATCC_1997      KQFPHLRLIVAHMGMPEYSEFLDLCEQHDEVRLDTTMAFTAFSNEKAPFP
Mflv_1007|M.gilvum_PYR-GCK          RSRPHLPLIVAHMGMPEYRDFLDLAHRFDGVYLDTTMAFTDFSERTHPFP
Mb3540c|M.bovis_AF2122/97           LDFPELVIVCGHVGYPWTEEMVAVARKHENVYIDT----SAYTIKRLPGK
Rv3510c|M.tuberculosis_H37Rv        LDFPELVIVCGHVGYPWTEEMVAVARKHENVYIDT----SAYTIKRLPGK
MAV_0646|M.avium_104                LDFPELVIVCGHVGYPWTEEMVAVARKHENVYIDT----SAYTIERLPDE
MMAR_4998|M.marinum_M               LDFPELVIVCGHVGYPWTEEMVAVARKHENVYIDT----SAYTIKRLPHE
MUL_3876|M.ulcerans_Agy99           VRFPELRLCMIHGADPWWDVAIRLLLKYSNSRLMT----SAWTPKRLPES
                                       *.* :   * . *     : :   ..   : *    : ::    *  

TH_1451|M.thermoresistible__bu      ADQYPRLAGLGERIVFGSDFPNIPYPYPHALQVLTELPGIDDDWLCNVLY
MSMEG_0628|M.smegmatis_MC2_155      PADRARLYDLGERILFGSDFPNIPYGYADALRHTVDLPGIDDTWRRNVLH
Mvan_0424|M.vanbaalenii_PYR-1       AGEYGRLRDMGDRILFGSDFPNIPYGYTHAMSVLTELPCVDDTWLRNVFH
MAB_4667|M.abscessus_ATCC_1997      ESDYPRLVEMGHKIYFGSDFPNIPYGYAEAITALRRMPGIDDAWMRDVLY
Mflv_1007|M.gilvum_PYR-GCK          QSARADLLALGDKVLFGSDYPNIPYSYQHAVESITRL-GLGPEWCRKVLR
Mb3540c|M.bovis_AF2122/97           LVRFMKTDTGQRKVLFGTNYPMIAH--THALTGLDEL-GLSDEARRDFLH
Rv3510c|M.tuberculosis_H37Rv        LVRFMKTDTGQRKVLFGTNYPMIAH--THALTGLDEL-GLSDEARRDFLH
MAV_0646|M.avium_104                LVRFIKTGTGQRKVLFGTNYPMITA--EHALAGLDGL-GLSDEARRDFLH
MMAR_4998|M.marinum_M               LIRFMKTGTGRRKVMFGTNFPMIAH--AHALAGLDEL-GLEDEARRDFLH
MUL_3876|M.ulcerans_Agy99           LLHYMRTRG-KNKVIFASDWPVLRMR---RVVPEARALDLPADVLANYLY
                                                :: *.:::* :       :        :      . : 

TH_1451|M.thermoresistible__bu      RNAAELFRV--------------------
MSMEG_0628|M.smegmatis_MC2_155      DNAARLFGVASR-----------------
Mvan_0424|M.vanbaalenii_PYR-1       DNAVRLFGATGSCPGLPSAEPHRVRKAAP
MAB_4667|M.abscessus_ATCC_1997      HNGARLFGVDTSASGR-------------
Mflv_1007|M.gilvum_PYR-GCK          DNAVRLFAL--------------------
Mb3540c|M.bovis_AF2122/97           GNAVRVFKLDPRGKVQT------------
Rv3510c|M.tuberculosis_H37Rv        GNAVRVFKLDPRGKVQT------------
MAV_0646|M.avium_104                GNAERVFRLEAAT----------------
MMAR_4998|M.marinum_M               GNAERVFGLAQRPPR--------------
MUL_3876|M.ulcerans_Agy99           NNAQEFFFGEESGR---------------
                                     *. ..*