For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_0626 (speE)

annotation: PROBABLE SPERMIDINE SYNTHASE SPEE (PUTRESCINE AMINOPROPYLTRANSFERASE) (AMINOPROPYLTRANSFERASE) (SPDSY)
coordinates: 1368025 - 1369524
length: 500

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0626speE-100% (500)PROBABLE SPERMIDINE SYNTHASE SPEE (PUTRESCINE AMINOPROPYLTRANSFERASE) (AMINOPROPYLTRANSFERASE) (SPDSY)
M. thermoresistible (build 8)TH_4293-7e-0525.42% (177) PUTATIVE putative protein of unknown function DUF81

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2632speE0.077.84% (501) spermidine synthase
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv2601speE0.077.84% (501) spermidine synthase
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_2104speE0.078.16% (499) spermidine synthase, SpeE
M. avium 104MAV_3480-0.077.64% (501) spermidine synthase
M. smegmatis MC2 155MSMEG_5387-8e-0628.70% (216) hypothetical protein MSMEG_5387
M. ulcerans Agy99MUL_1708speE0.077.87% (497) spermidine synthase
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2104|M.marinum_M               MTATDHAPAPDTVGTVTASGRWRALLLAAVAACAACGIIYELALLTLSTS
MUL_1708|M.ulcerans_Agy99           MTATDHAPAPDTVGTVTASGRSRTLLLAAVAACAACGIIYEIALLTLSTS
MAV_3480|M.avium_104                -MSTVEVSAPEAAP--PSPGRWRALLLAAVAACAACGIIYELALLTLSAS
Mb2632|M.bovis_AF2122/97            MTSTRQAGEATEAS-----VRWRAVLLAAVAACAACGLVYELALLTLAAS
Rv2601|M.tuberculosis_H37Rv         MTSTRQAGEATEAS-----VRWRAVLLAAVAACAACGLVYELALLTLAAS
TH_0626|M.thermoresistible__bu      -----------------------------VAACAACGLIYELALLTLSAS
MSMEG_5387|M.smegmatis_MC2_155      MIALTIVLAVFVG--------------IALGMLGGGGSILTVPLLAYVAG
                                                                 :.  .. * :  :.**:  :.

MMAR_2104|M.marinum_M               LDGGGIVATSLIVAGYIAALGAGALLVKPLLAHAAIAFIAVEVLLGIIGG
MUL_1708|M.ulcerans_Agy99           LDGGGIVATSLIVAGYIAALGAGALLVKPLLAHAAIAFIAVEVLLGMIGG
MAV_3480|M.avium_104                LDGGGIVATSLIVAGYIAALGVGALLAKPLLAHAALGFIAVEALLGVVGG
Mb2632|M.bovis_AF2122/97            LNGGGIVATSLIVAGYIAALGAGALLIKPLLAHAAIAFIAVEAVLGIIGG
Rv2601|M.tuberculosis_H37Rv         LNGGGIVATSLIVAGYIAALGAGALLIKPLLAHAAIAFIAVEAVLGIIGG
TH_0626|M.thermoresistible__bu      VHGGGIVATSLIVAGYVAALGAGALLVKPLLGHAAITFIAVETLLGIIGG
MSMEG_5387|M.smegmatis_MC2_155      MDAKQAVTTSLLVVGVTSAVSA--------VSHARAGRVQWR------AG
                                    :..   *:***:*.*  :*:..        :.**    :  .      .*

MMAR_2104|M.marinum_M               LSAAALYVAFAFIDG---STWVLALGTALIGGLVGAEVPLLMTLLQRGRL
MUL_1708|M.ulcerans_Agy99           LSAAALYVAFAFIDG---STWVLALGTALIGGLVGAEVPLLMTLLQRGRL
MAV_3480|M.avium_104                LSAAALYVVFAFLDGSVGSTWVLAVSTALIGGLVGAEVPLLMTLLQRGRT
Mb2632|M.bovis_AF2122/97            LSAAALYAAFAFLDELDGSTLVLAVGTALIGGLVGAEVPLLMTLLQRGRV
Rv2601|M.tuberculosis_H37Rv         LSAAALYAAFAFLDELDGSTLVLAVGTALIGGLVGAEVPLLMTLLQRGRV
TH_0626|M.thermoresistible__bu      LSAAALYLAFVFIGG---SLWVLVVGTALIGCLVGAEVPLLMTLLQRGRV
MSMEG_5387|M.smegmatis_MC2_155      LSFGAAGMAGAYAGG---VLGRFIPGTALLIAFAVVMVAAAIPMLR-GRR
                                    ** .*   . .: .        :  .***:  :. . *.  :.:*: ** 

MMAR_2104|M.marinum_M               AEAADTGRTLANLNAADYLGALIGGLVWPFVLLPHLGMIRGAAATGIVNL
MUL_1708|M.ulcerans_Agy99           AEAADTGRTLANLNAADYLGALIGGLVWPFVLLPHLGMIRGAAATGIVNL
MAV_3480|M.avium_104                AGPADAGRTLANLNAADYLGALLGGLVWPFLLLPQLGMIRGAAATGMINL
Mb2632|M.bovis_AF2122/97            AGAADAGRTLANLNAADYLGALVGGLAWPFLLLPQLGMIRGAAVTGIVNL
Rv2601|M.tuberculosis_H37Rv         AGAADAGRTLANLNAADYLGALVGGLAWPFLLLPQLGMIRGAAVTGIVNL
TH_0626|M.thermoresistible__bu      AGAADTGRVLANLNAADYLGALIGGLSWPFLLLPQLGMIRGAAVTGVINL
MSMEG_5387|M.smegmatis_MC2_155      APEATTAHGLPVVRVVS-LGLAVGGLT---------GMIG--AGGGFLVV
                                    *  * :.: *. :.... **  :***          ***   *  *.: :

MMAR_2104|M.marinum_M               VAAAVVSIFLLRQVVSTRQLAMALSSLLAALGLLVTLLVHARDIETTSRQ
MUL_1708|M.ulcerans_Agy99           VAAAVVSIFLLRQVVSTRQLAMALCSLLAALGLLVTLLVHARDIETTSRQ
MAV_3480|M.avium_104                AAAAVVAIFLLRQVVSARQLALALCALAAALALLATLLLRSADVETTSRQ
Mb2632|M.bovis_AF2122/97            AAAGVVSIFLLRHVVSGRQLVTALCALAAALGLIATLLVHSHDIETTGRQ
Rv2601|M.tuberculosis_H37Rv         AAAGVVSIFLLRHVVSGRQLVTALCALAAALGLIATLLVHSHDIETTGRQ
TH_0626|M.thermoresistible__bu      TAAAVVAVFLLRHIISGRQLAAALGVLAAALTLLTTLLVRADGIETTSRQ
MSMEG_5387|M.smegmatis_MC2_155      PALTLLGGLPMPAAVGTSLIVIALNSFSGLAGHLTGLQIDWALAAAVTG-
                                     *  ::. : :   :.   :. **  : .    :. * :      :.   

MMAR_2104|M.marinum_M               ELYADPIIAYRHTSYQEIVVTRRGNDLRLYLDGGLQFSTRDEYRYTESLV
MUL_1708|M.ulcerans_Agy99           ELYADPIIAYRHTSYQEIVVTRRGNDLRLYLDGGLQFSTRDEYRYTESLV
MAV_3480|M.avium_104                RLYADPIIAYRHTPYQEIVVTRRGDDTRLYLDGGLQFSTRDEYRYTESLV
Mb2632|M.bovis_AF2122/97            QLYADPIIAYRHSAYQEIVVTRRGDDLRLYLDGGLQFCTRDEYRYTESLV
Rv2601|M.tuberculosis_H37Rv         QLYADPIIAYRHSAYQEIVVTRRGDDLRLYLDGGLQFCTRDEYRYTESLV
TH_0626|M.thermoresistible__bu      RLYADPIIAYERSPYQEIVITRRGADLRLYLDGGLQFSTRDEHRYTESLV
MSMEG_5387|M.smegmatis_MC2_155      AAVAGCLIGTR------LITKINADALRKAFG---WFVLAMSSVILAQEI
                                       *. :*. .      :: . ..   *  :.    *    .     . :

MMAR_2104|M.marinum_M               YPALGDGARSVLVLGGGDGLAARELLRLPRIERIVQVELDPAVIELARTT
MUL_1708|M.ulcerans_Agy99           YPALGDGARSVLVLGGGDGLAARELLRLPRIERIVQVELDPAVIELARTT
MAV_3480|M.avium_104                YPALGNGARSVLVLGGGDGLAARELLRQPGISRIVQVELDPAVIEIARTT
Mb2632|M.bovis_AF2122/97            YPAVSDGARSVLVLGGGDGLAARELLRQPGIEQIVQVELDPAVIELARTT
Rv2601|M.tuberculosis_H37Rv         YPAVSDGARSVLVLGGGDGLAARELLRQPGIEQIVQVELDPAVIELARTT
TH_0626|M.thermoresistible__bu      HPALDESTRSVLILGGGDGLAARELLRYPGIDSIVQVELDPAVIELARTT
MSMEG_5387|M.smegmatis_MC2_155      HPFVGLAAASLTVIAASMTMVCARFSRCP---------------------
                                    :* :. .: *: ::...  :.. .: * *                     

MMAR_2104|M.marinum_M               MREANGGALDDPRVQVVIGDAMKWLRGTDSGQ--SRRFDAVIVDLPDPDT
MUL_1708|M.ulcerans_Agy99           MREANGGALDDPRVQVVIGDAMKWLRGTDSGQ--SRRFDAVIVDLPDPDT
MAV_3480|M.avium_104                LRAANGGSLDNPRVRVLTGDAMAWLRGPNPD-----RFDAVIVDLPDPDT
Mb2632|M.bovis_AF2122/97            LRDVNAGSLDNPRVHVVIDDAMSWLRGAAVP---PAGFDAVIVDLRDPDT
Rv2601|M.tuberculosis_H37Rv         LRDVNAGSLDNPRVHVVIDDAMSWLRGAAVP---PAGFDAVIVDLRDPDT
TH_0626|M.thermoresistible__bu      LRPVNGGALDDPRVTVVTDDAMRWLREPPPDLRPPGGFDAVIVDLPDPDT
MSMEG_5387|M.smegmatis_MC2_155      LRRVTRLSMARPAVA-----------------------------------
                                    :* ..  ::  * *                                    

MMAR_2104|M.marinum_M               PALGRLYSAEFYALAAHALAPDGLMVVQAGSPFSTPTAFWRTVSTIKAAG
MUL_1708|M.ulcerans_Agy99           PALGRLYSAEFYALAAHALAPDGLMVVQAGSPFSTPTAFWRTVSTIKAAG
MAV_3480|M.avium_104                PVLGRLYSTEFYTLAARALAPGGLLVVQAGSPFSTPTAYWRTVSTIRAAG
Mb2632|M.bovis_AF2122/97            PVLGRLYSTEFYALAARALAPGGLMVVQAGSPYSTPTAFWRIISTIRSAG
Rv2601|M.tuberculosis_H37Rv         PVLGRLYSTEFYALAARALAPGGLMVVQAGSPYSTPTAFWRIISTIRSAG
TH_0626|M.thermoresistible__bu      PVLGRLYSTEFYALVTRALAPGGRMVVQAGSPYSTPTAFWRTVSTIASAG
MSMEG_5387|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2104|M.marinum_M               YAVTPYHVHVPTFGDWGFALARRGGTAPIPAVPADAPSLRFLNQPVLNAA
MUL_1708|M.ulcerans_Agy99           YAVTPYHVHVPTFGDWGFALARRGGTAPIPAVPADAPSLRFLNQPVLNAA
MAV_3480|M.avium_104                YAVTPYHVHVPTFGDWGFVLAQRGDTPPAPKVPPDAPPLRFLDQRVLQAA
Mb2632|M.bovis_AF2122/97            YAVTPYHVHVPTFGDWGFALARLTDIAPTPAVPSTAPALRFLDQQVLEAA
Rv2601|M.tuberculosis_H37Rv         YAVTPYHVHVPTFGDWGFALARLTDIAPTPAVPSTAPALRFLDQQVLEAA
TH_0626|M.thermoresistible__bu      YAVTPYHVHVPTFGDWGFVLATRGTEPPRPTVPANAPELRFLDQRVLDAA
MSMEG_5387|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2104|M.marinum_M               TVFSSDVGPTMLEPSTLDNPRIVEDMRRGYR--
MUL_1708|M.ulcerans_Agy99           TVFSSDVGPTMLEPSTLDNPRIVEDMRPGLRRC
MAV_3480|M.avium_104                VVFSGDVGPRPLEPSTLDNPRIVGDMRHGYD--
Mb2632|M.bovis_AF2122/97            TVFSGDIRPRTLDPSTLDNPHIVEDMRHGWD--
Rv2601|M.tuberculosis_H37Rv         TVFSGDIRPRTLDPSTLDNPHIVEDMRHGWD--
TH_0626|M.thermoresistible__bu      TVFGKDRPPLTLEPSTLDRPRVVDDIRRGWQ--
MSMEG_5387|M.smegmatis_MC2_155      ---------------------------------