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TATDHAPAPDTVGTVTASGRSRTLLLAAVAACAACGIIYEIALLTLSTSLDGGGIVATSLIVAGYIAALG AGALLVKPLLAHAAIAFIAVEVLLGMIGGLSAAALYVAFAFIDGSTWVLALGTALIGGLVGAEVPLLMTL LQRGRLAEAADTGRTLANLNAADYLGALIGGLVWPFVLLPHLGMIRGAAATGIVNLVAAAVVSIFLLRQV VSTRQLAMALCSLLAALGLLVTLLVHARDIETTSRQELYADPIIAYRHTSYQEIVVTRRGNDLRLYLDGG LQFSTRDEYRYTESLVYPALGDGARSVLVLGGGDGLAARELLRLPRIERIVQVELDPAVIELARTTMREA NGGALDDPRVQVVIGDAMKWLRGTDSGQSRRFDAVIVDLPDPDTPALGRLYSAEFYALAAHALAPDGLMV VQAGSPFSTPTAFWRTVSTIKAAGYAVTPYHVHVPTFGDWGFALARRGGTAPIPAVPADAPSLRFLNQPV LNAATVFSSDVGPTMLEPSTLDNPRIVEDMRPGLRRC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1708 | speE | - | 100% (528) | spermidine synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2632 | speE | 0.0 | 80.78% (510) | spermidine synthase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2601 | speE | 0.0 | 80.78% (510) | spermidine synthase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2104 | speE | 0.0 | 98.67% (526) | spermidine synthase, SpeE |
| M. avium 104 | MAV_3480 | - | 0.0 | 82.48% (508) | spermidine synthase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_0626 | speE | 0.0 | 77.87% (497) | PROBABLE SPERMIDINE SYNTHASE SPEE (PUTRESCINE |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1708|M.ulcerans_Agy99 MTATDHAPAPDTVGTVTASGRSRTLLLAAVAACAACGIIYEIALLTLSTS
MMAR_2104|M.marinum_M MTATDHAPAPDTVGTVTASGRWRALLLAAVAACAACGIIYELALLTLSTS
MAV_3480|M.avium_104 -MSTVEVSAPEAAP--PSPGRWRALLLAAVAACAACGIIYELALLTLSAS
Mb2632|M.bovis_AF2122/97 MTSTRQAGEATEAS-----VRWRAVLLAAVAACAACGLVYELALLTLAAS
Rv2601|M.tuberculosis_H37Rv MTSTRQAGEATEAS-----VRWRAVLLAAVAACAACGLVYELALLTLAAS
TH_0626|M.thermoresistible__bu -----------------------------VAACAACGLIYELALLTLSAS
********::**:*****::*
MUL_1708|M.ulcerans_Agy99 LDGGGIVATSLIVAGYIAALGAGALLVKPLLAHAAIAFIAVEVLLGMIGG
MMAR_2104|M.marinum_M LDGGGIVATSLIVAGYIAALGAGALLVKPLLAHAAIAFIAVEVLLGIIGG
MAV_3480|M.avium_104 LDGGGIVATSLIVAGYIAALGVGALLAKPLLAHAALGFIAVEALLGVVGG
Mb2632|M.bovis_AF2122/97 LNGGGIVATSLIVAGYIAALGAGALLIKPLLAHAAIAFIAVEAVLGIIGG
Rv2601|M.tuberculosis_H37Rv LNGGGIVATSLIVAGYIAALGAGALLIKPLLAHAAIAFIAVEAVLGIIGG
TH_0626|M.thermoresistible__bu VHGGGIVATSLIVAGYVAALGAGALLVKPLLGHAAITFIAVETLLGIIGG
:.**************:****.**** ****.***: *****.:**::**
MUL_1708|M.ulcerans_Agy99 LSAAALYVAFAFIDG---STWVLALGTALIGGLVGAEVPLLMTLLQRGRL
MMAR_2104|M.marinum_M LSAAALYVAFAFIDG---STWVLALGTALIGGLVGAEVPLLMTLLQRGRL
MAV_3480|M.avium_104 LSAAALYVVFAFLDGSVGSTWVLAVSTALIGGLVGAEVPLLMTLLQRGRT
Mb2632|M.bovis_AF2122/97 LSAAALYAAFAFLDELDGSTLVLAVGTALIGGLVGAEVPLLMTLLQRGRV
Rv2601|M.tuberculosis_H37Rv LSAAALYAAFAFLDELDGSTLVLAVGTALIGGLVGAEVPLLMTLLQRGRV
TH_0626|M.thermoresistible__bu LSAAALYLAFVFIGG---SLWVLVVGTALIGCLVGAEVPLLMTLLQRGRV
******* .*.*:. * **.:.***** *****************
MUL_1708|M.ulcerans_Agy99 AEAADTGRTLANLNAADYLGALIGGLVWPFVLLPHLGMIRGAAATGIVNL
MMAR_2104|M.marinum_M AEAADTGRTLANLNAADYLGALIGGLVWPFVLLPHLGMIRGAAATGIVNL
MAV_3480|M.avium_104 AGPADAGRTLANLNAADYLGALLGGLVWPFLLLPQLGMIRGAAATGMINL
Mb2632|M.bovis_AF2122/97 AGAADAGRTLANLNAADYLGALVGGLAWPFLLLPQLGMIRGAAVTGIVNL
Rv2601|M.tuberculosis_H37Rv AGAADAGRTLANLNAADYLGALVGGLAWPFLLLPQLGMIRGAAVTGIVNL
TH_0626|M.thermoresistible__bu AGAADTGRVLANLNAADYLGALIGGLSWPFLLLPQLGMIRGAAVTGVINL
* .**:**.*************:*** ***:***:********.**::**
MUL_1708|M.ulcerans_Agy99 VAAAVVSIFLLRQVVSTRQLAMALCSLLAALGLLVTLLVHARDIETTSRQ
MMAR_2104|M.marinum_M VAAAVVSIFLLRQVVSTRQLAMALSSLLAALGLLVTLLVHARDIETTSRQ
MAV_3480|M.avium_104 AAAAVVAIFLLRQVVSARQLALALCALAAALALLATLLLRSADVETTSRQ
Mb2632|M.bovis_AF2122/97 AAAGVVSIFLLRHVVSGRQLVTALCALAAALGLIATLLVHSHDIETTGRQ
Rv2601|M.tuberculosis_H37Rv AAAGVVSIFLLRHVVSGRQLVTALCALAAALGLIATLLVHSHDIETTGRQ
TH_0626|M.thermoresistible__bu TAAAVVAVFLLRHIISGRQLAAALGVLAAALTLLTTLLVRADGIETTSRQ
.**.**::****:::* ***. ** * *** *:.***::: .:***.**
MUL_1708|M.ulcerans_Agy99 ELYADPIIAYRHTSYQEIVVTRRGNDLRLYLDGGLQFSTRDEYRYTESLV
MMAR_2104|M.marinum_M ELYADPIIAYRHTSYQEIVVTRRGNDLRLYLDGGLQFSTRDEYRYTESLV
MAV_3480|M.avium_104 RLYADPIIAYRHTPYQEIVVTRRGDDTRLYLDGGLQFSTRDEYRYTESLV
Mb2632|M.bovis_AF2122/97 QLYADPIIAYRHSAYQEIVVTRRGDDLRLYLDGGLQFCTRDEYRYTESLV
Rv2601|M.tuberculosis_H37Rv QLYADPIIAYRHSAYQEIVVTRRGDDLRLYLDGGLQFCTRDEYRYTESLV
TH_0626|M.thermoresistible__bu RLYADPIIAYERSPYQEIVITRRGADLRLYLDGGLQFSTRDEHRYTESLV
.*********.::.*****:**** * **********.****:*******
MUL_1708|M.ulcerans_Agy99 YPALGDGARSVLVLGGGDGLAARELLRLPRIERIVQVELDPAVIELARTT
MMAR_2104|M.marinum_M YPALGDGARSVLVLGGGDGLAARELLRLPRIERIVQVELDPAVIELARTT
MAV_3480|M.avium_104 YPALGNGARSVLVLGGGDGLAARELLRQPGISRIVQVELDPAVIEIARTT
Mb2632|M.bovis_AF2122/97 YPAVSDGARSVLVLGGGDGLAARELLRQPGIEQIVQVELDPAVIELARTT
Rv2601|M.tuberculosis_H37Rv YPAVSDGARSVLVLGGGDGLAARELLRQPGIEQIVQVELDPAVIELARTT
TH_0626|M.thermoresistible__bu HPALDESTRSVLILGGGDGLAARELLRYPGIDSIVQVELDPAVIELARTT
:**:.:.:****:************** * *. ************:****
MUL_1708|M.ulcerans_Agy99 MREANGGALDDPRVQVVIGDAMKWLRGTDSGQ--SRRFDAVIVDLPDPDT
MMAR_2104|M.marinum_M MREANGGALDDPRVQVVIGDAMKWLRGTDSGQ--SRRFDAVIVDLPDPDT
MAV_3480|M.avium_104 LRAANGGSLDNPRVRVLTGDAMAWLRGPNPD-----RFDAVIVDLPDPDT
Mb2632|M.bovis_AF2122/97 LRDVNAGSLDNPRVHVVIDDAMSWLRGAAVP---PAGFDAVIVDLRDPDT
Rv2601|M.tuberculosis_H37Rv LRDVNAGSLDNPRVHVVIDDAMSWLRGAAVP---PAGFDAVIVDLRDPDT
TH_0626|M.thermoresistible__bu LRPVNGGALDDPRVTVVTDDAMRWLREPPPDLRPPGGFDAVIVDLPDPDT
:* .*.*:**:*** *: .*** *** . ******** ****
MUL_1708|M.ulcerans_Agy99 PALGRLYSAEFYALAAHALAPDGLMVVQAGSPFSTPTAFWRTVSTIKAAG
MMAR_2104|M.marinum_M PALGRLYSAEFYALAAHALAPDGLMVVQAGSPFSTPTAFWRTVSTIKAAG
MAV_3480|M.avium_104 PVLGRLYSTEFYTLAARALAPGGLLVVQAGSPFSTPTAYWRTVSTIRAAG
Mb2632|M.bovis_AF2122/97 PVLGRLYSTEFYALAARALAPGGLMVVQAGSPYSTPTAFWRIISTIRSAG
Rv2601|M.tuberculosis_H37Rv PVLGRLYSTEFYALAARALAPGGLMVVQAGSPYSTPTAFWRIISTIRSAG
TH_0626|M.thermoresistible__bu PVLGRLYSTEFYALVTRALAPGGRMVVQAGSPYSTPTAFWRTVSTIASAG
*.******:***:*.::****.* :*******:*****:** :*** :**
MUL_1708|M.ulcerans_Agy99 YAVTPYHVHVPTFGDWGFALARRGGTAPIPAVPADAPSLRFLNQPVLNAA
MMAR_2104|M.marinum_M YAVTPYHVHVPTFGDWGFALARRGGTAPIPAVPADAPSLRFLNQPVLNAA
MAV_3480|M.avium_104 YAVTPYHVHVPTFGDWGFVLAQRGDTPPAPKVPPDAPPLRFLDQRVLQAA
Mb2632|M.bovis_AF2122/97 YAVTPYHVHVPTFGDWGFALARLTDIAPTPAVPSTAPALRFLDQQVLEAA
Rv2601|M.tuberculosis_H37Rv YAVTPYHVHVPTFGDWGFALARLTDIAPTPAVPSTAPALRFLDQQVLEAA
TH_0626|M.thermoresistible__bu YAVTPYHVHVPTFGDWGFVLATRGTEPPRPTVPANAPELRFLDQRVLDAA
******************.** .* * **. ** ****:* **:**
MUL_1708|M.ulcerans_Agy99 TVFSSDVGPTMLEPSTLDNPRIVEDMRPGLRRC
MMAR_2104|M.marinum_M TVFSSDVGPTMLEPSTLDNPRIVEDMRRGYR--
MAV_3480|M.avium_104 VVFSGDVGPRPLEPSTLDNPRIVGDMRHGYD--
Mb2632|M.bovis_AF2122/97 TVFSGDIRPRTLDPSTLDNPHIVEDMRHGWD--
Rv2601|M.tuberculosis_H37Rv TVFSGDIRPRTLDPSTLDNPHIVEDMRHGWD--
TH_0626|M.thermoresistible__bu TVFGKDRPPLTLEPSTLDRPRVVDDIRRGWQ--
.**. * * *:*****.*::* *:* *