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MTSTRQAGEATEASVRWRAVLLAAVAACAACGLVYELALLTLAASLNGGGIVATSLIVAGYIAALGAGAL LIKPLLAHAAIAFIAVEAVLGIIGGLSAAALYAAFAFLDELDGSTLVLAVGTALIGGLVGAEVPLLMTLL QRGRVAGAADAGRTLANLNAADYLGALVGGLAWPFLLLPQLGMIRGAAVTGIVNLAAAGVVSIFLLRHVV SGRQLVTALCALAAALGLIATLLVHSHDIETTGRQQLYADPIIAYRHSAYQEIVVTRRGDDLRLYLDGGL QFCTRDEYRYTESLVYPAVSDGARSVLVLGGGDGLAARELLRQPGIEQIVQVELDPAVIELARTTLRDVN AGSLDNPRVHVVIDDAMSWLRGAAVPPAGFDAVIVDLRDPDTPVLGRLYSTEFYALAARALAPGGLMVVQ AGSPYSTPTAFWRIISTIRSAGYAVTPYHVHVPTFGDWGFALARLTDIAPTPAVPSTAPALRFLDQQVLE AATVFSGDIRPRTLDPSTLDNPHIVEDMRHGWD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2601 | speE | - | 100% (523) | spermidine synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2632 | speE | 0.0 | 100.00% (523) | spermidine synthase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2104 | speE | 0.0 | 81.21% (511) | spermidine synthase, SpeE |
| M. avium 104 | MAV_3480 | - | 0.0 | 81.69% (508) | spermidine synthase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_0626 | speE | 0.0 | 77.84% (501) | PROBABLE SPERMIDINE SYNTHASE SPEE (PUTRESCINE |
| M. ulcerans Agy99 | MUL_1708 | speE | 0.0 | 80.78% (510) | spermidine synthase |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2601|M.tuberculosis_H37Rv MTSTRQAGEATEAS-----VRWRAVLLAAVAACAACGLVYELALLTLAAS
Mb2632|M.bovis_AF2122/97 MTSTRQAGEATEAS-----VRWRAVLLAAVAACAACGLVYELALLTLAAS
MMAR_2104|M.marinum_M MTATDHAPAPDTVGTVTASGRWRALLLAAVAACAACGIIYELALLTLSTS
MUL_1708|M.ulcerans_Agy99 MTATDHAPAPDTVGTVTASGRSRTLLLAAVAACAACGIIYEIALLTLSTS
MAV_3480|M.avium_104 -MSTVEVSAPEAAP--PSPGRWRALLLAAVAACAACGIIYELALLTLSAS
TH_0626|M.thermoresistible__bu -----------------------------VAACAACGLIYELALLTLSAS
********::**:*****::*
Rv2601|M.tuberculosis_H37Rv LNGGGIVATSLIVAGYIAALGAGALLIKPLLAHAAIAFIAVEAVLGIIGG
Mb2632|M.bovis_AF2122/97 LNGGGIVATSLIVAGYIAALGAGALLIKPLLAHAAIAFIAVEAVLGIIGG
MMAR_2104|M.marinum_M LDGGGIVATSLIVAGYIAALGAGALLVKPLLAHAAIAFIAVEVLLGIIGG
MUL_1708|M.ulcerans_Agy99 LDGGGIVATSLIVAGYIAALGAGALLVKPLLAHAAIAFIAVEVLLGMIGG
MAV_3480|M.avium_104 LDGGGIVATSLIVAGYIAALGVGALLAKPLLAHAALGFIAVEALLGVVGG
TH_0626|M.thermoresistible__bu VHGGGIVATSLIVAGYVAALGAGALLVKPLLGHAAITFIAVETLLGIIGG
:.**************:****.**** ****.***: *****.:**::**
Rv2601|M.tuberculosis_H37Rv LSAAALYAAFAFLDELDGSTLVLAVGTALIGGLVGAEVPLLMTLLQRGRV
Mb2632|M.bovis_AF2122/97 LSAAALYAAFAFLDELDGSTLVLAVGTALIGGLVGAEVPLLMTLLQRGRV
MMAR_2104|M.marinum_M LSAAALYVAFAFIDG---STWVLALGTALIGGLVGAEVPLLMTLLQRGRL
MUL_1708|M.ulcerans_Agy99 LSAAALYVAFAFIDG---STWVLALGTALIGGLVGAEVPLLMTLLQRGRL
MAV_3480|M.avium_104 LSAAALYVVFAFLDGSVGSTWVLAVSTALIGGLVGAEVPLLMTLLQRGRT
TH_0626|M.thermoresistible__bu LSAAALYLAFVFIGG---SLWVLVVGTALIGCLVGAEVPLLMTLLQRGRV
******* .*.*:. * **.:.***** *****************
Rv2601|M.tuberculosis_H37Rv AGAADAGRTLANLNAADYLGALVGGLAWPFLLLPQLGMIRGAAVTGIVNL
Mb2632|M.bovis_AF2122/97 AGAADAGRTLANLNAADYLGALVGGLAWPFLLLPQLGMIRGAAVTGIVNL
MMAR_2104|M.marinum_M AEAADTGRTLANLNAADYLGALIGGLVWPFVLLPHLGMIRGAAATGIVNL
MUL_1708|M.ulcerans_Agy99 AEAADTGRTLANLNAADYLGALIGGLVWPFVLLPHLGMIRGAAATGIVNL
MAV_3480|M.avium_104 AGPADAGRTLANLNAADYLGALLGGLVWPFLLLPQLGMIRGAAATGMINL
TH_0626|M.thermoresistible__bu AGAADTGRVLANLNAADYLGALIGGLSWPFLLLPQLGMIRGAAVTGVINL
* .**:**.*************:*** ***:***:********.**::**
Rv2601|M.tuberculosis_H37Rv AAAGVVSIFLLRHVVSGRQLVTALCALAAALGLIATLLVHSHDIETTGRQ
Mb2632|M.bovis_AF2122/97 AAAGVVSIFLLRHVVSGRQLVTALCALAAALGLIATLLVHSHDIETTGRQ
MMAR_2104|M.marinum_M VAAAVVSIFLLRQVVSTRQLAMALSSLLAALGLLVTLLVHARDIETTSRQ
MUL_1708|M.ulcerans_Agy99 VAAAVVSIFLLRQVVSTRQLAMALCSLLAALGLLVTLLVHARDIETTSRQ
MAV_3480|M.avium_104 AAAAVVAIFLLRQVVSARQLALALCALAAALALLATLLLRSADVETTSRQ
TH_0626|M.thermoresistible__bu TAAAVVAVFLLRHIISGRQLAAALGVLAAALTLLTTLLVRADGIETTSRQ
.**.**::****:::* ***. ** * *** *:.***::: .:***.**
Rv2601|M.tuberculosis_H37Rv QLYADPIIAYRHSAYQEIVVTRRGDDLRLYLDGGLQFCTRDEYRYTESLV
Mb2632|M.bovis_AF2122/97 QLYADPIIAYRHSAYQEIVVTRRGDDLRLYLDGGLQFCTRDEYRYTESLV
MMAR_2104|M.marinum_M ELYADPIIAYRHTSYQEIVVTRRGNDLRLYLDGGLQFSTRDEYRYTESLV
MUL_1708|M.ulcerans_Agy99 ELYADPIIAYRHTSYQEIVVTRRGNDLRLYLDGGLQFSTRDEYRYTESLV
MAV_3480|M.avium_104 RLYADPIIAYRHTPYQEIVVTRRGDDTRLYLDGGLQFSTRDEYRYTESLV
TH_0626|M.thermoresistible__bu RLYADPIIAYERSPYQEIVITRRGADLRLYLDGGLQFSTRDEHRYTESLV
.*********.::.*****:**** * **********.****:*******
Rv2601|M.tuberculosis_H37Rv YPAVSDGARSVLVLGGGDGLAARELLRQPGIEQIVQVELDPAVIELARTT
Mb2632|M.bovis_AF2122/97 YPAVSDGARSVLVLGGGDGLAARELLRQPGIEQIVQVELDPAVIELARTT
MMAR_2104|M.marinum_M YPALGDGARSVLVLGGGDGLAARELLRLPRIERIVQVELDPAVIELARTT
MUL_1708|M.ulcerans_Agy99 YPALGDGARSVLVLGGGDGLAARELLRLPRIERIVQVELDPAVIELARTT
MAV_3480|M.avium_104 YPALGNGARSVLVLGGGDGLAARELLRQPGISRIVQVELDPAVIEIARTT
TH_0626|M.thermoresistible__bu HPALDESTRSVLILGGGDGLAARELLRYPGIDSIVQVELDPAVIELARTT
:**:.:.:****:************** * *. ************:****
Rv2601|M.tuberculosis_H37Rv LRDVNAGSLDNPRVHVVIDDAMSWLRGAAVP---PAGFDAVIVDLRDPDT
Mb2632|M.bovis_AF2122/97 LRDVNAGSLDNPRVHVVIDDAMSWLRGAAVP---PAGFDAVIVDLRDPDT
MMAR_2104|M.marinum_M MREANGGALDDPRVQVVIGDAMKWLRGTDSGQ--SRRFDAVIVDLPDPDT
MUL_1708|M.ulcerans_Agy99 MREANGGALDDPRVQVVIGDAMKWLRGTDSGQ--SRRFDAVIVDLPDPDT
MAV_3480|M.avium_104 LRAANGGSLDNPRVRVLTGDAMAWLRGPNPD-----RFDAVIVDLPDPDT
TH_0626|M.thermoresistible__bu LRPVNGGALDDPRVTVVTDDAMRWLREPPPDLRPPGGFDAVIVDLPDPDT
:* .*.*:**:*** *: .*** *** . ******** ****
Rv2601|M.tuberculosis_H37Rv PVLGRLYSTEFYALAARALAPGGLMVVQAGSPYSTPTAFWRIISTIRSAG
Mb2632|M.bovis_AF2122/97 PVLGRLYSTEFYALAARALAPGGLMVVQAGSPYSTPTAFWRIISTIRSAG
MMAR_2104|M.marinum_M PALGRLYSAEFYALAAHALAPDGLMVVQAGSPFSTPTAFWRTVSTIKAAG
MUL_1708|M.ulcerans_Agy99 PALGRLYSAEFYALAAHALAPDGLMVVQAGSPFSTPTAFWRTVSTIKAAG
MAV_3480|M.avium_104 PVLGRLYSTEFYTLAARALAPGGLLVVQAGSPFSTPTAYWRTVSTIRAAG
TH_0626|M.thermoresistible__bu PVLGRLYSTEFYALVTRALAPGGRMVVQAGSPYSTPTAFWRTVSTIASAG
*.******:***:*.::****.* :*******:*****:** :*** :**
Rv2601|M.tuberculosis_H37Rv YAVTPYHVHVPTFGDWGFALARLTDIAPTPAVPSTAPALRFLDQQVLEAA
Mb2632|M.bovis_AF2122/97 YAVTPYHVHVPTFGDWGFALARLTDIAPTPAVPSTAPALRFLDQQVLEAA
MMAR_2104|M.marinum_M YAVTPYHVHVPTFGDWGFALARRGGTAPIPAVPADAPSLRFLNQPVLNAA
MUL_1708|M.ulcerans_Agy99 YAVTPYHVHVPTFGDWGFALARRGGTAPIPAVPADAPSLRFLNQPVLNAA
MAV_3480|M.avium_104 YAVTPYHVHVPTFGDWGFVLAQRGDTPPAPKVPPDAPPLRFLDQRVLQAA
TH_0626|M.thermoresistible__bu YAVTPYHVHVPTFGDWGFVLATRGTEPPRPTVPANAPELRFLDQRVLDAA
******************.** .* * **. ** ****:* **:**
Rv2601|M.tuberculosis_H37Rv TVFSGDIRPRTLDPSTLDNPHIVEDMRHGWD--
Mb2632|M.bovis_AF2122/97 TVFSGDIRPRTLDPSTLDNPHIVEDMRHGWD--
MMAR_2104|M.marinum_M TVFSSDVGPTMLEPSTLDNPRIVEDMRRGYR--
MUL_1708|M.ulcerans_Agy99 TVFSSDVGPTMLEPSTLDNPRIVEDMRPGLRRC
MAV_3480|M.avium_104 VVFSGDVGPRPLEPSTLDNPRIVGDMRHGYD--
TH_0626|M.thermoresistible__bu TVFGKDRPPLTLEPSTLDRPRVVDDIRRGWQ--
.**. * * *:*****.*::* *:* *