For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_0532 (-)

annotation: putative thiolase
coordinates: 1140431 - 1141582
length: 384

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0532--100% (384)putative thiolase
M. thermoresistible (build 8)TH_3921-e-13660.42% (384) PUTATIVE lipid-transfer protein
M. thermoresistible (build 8)TH_4006-e-13460.21% (377) PUTATIVE conserved hypothetical protein; putative thiolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1653c-4e-5134.24% (403) lipid-transfer protein
M. gilvum PYR-GCKMflv_2519-0.088.19% (381) thiolase
M. tuberculosis H37RvRv1627c-4e-5134.24% (403) lipid-transfer protein
M. leprae Br4923MLBr_02158-3e-2757.89% (114) hypothetical protein MLBr_02158
M. abscessus ATCC 19977MAB_2619-1e-5435.79% (394) lipid-transfer protein
M. marinum MMMAR_2430-1e-5035.25% (400) nonspecific lipid-transfer protein
M. avium 104MAV_0989-0.089.15% (378) putative thiolase
M. smegmatis MC2 155MSMEG_4778-0.088.36% (378) putative thiolase
M. ulcerans Agy99MUL_4955ltp1_16e-4932.43% (404) lipid-transfer protein Ltp1_1
M. vanbaalenii PYR-1Mvan_4139-0.089.63% (376) thiolase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1653c|M.bovis_AF2122/97           --MRMS-APEPVYILGAGMHPWGKW-GNDFTEYGVVAARAALRDAGVDWR
Rv1627c|M.tuberculosis_H37Rv        --MRMS-APEPVYILGAGMHPWGKW-GNDFTEYGVVAARAALRDAGVDWR
MMAR_2430|M.marinum_M               ----MS-APEPLYILGAGMHPWGKW-GNDFTEYGVAAARAALREAGLEWR
MAB_2619|M.abscessus_ATCC_1997      ----MSRTPDPVYILGAGMHPWGKW-GRDFTEYGVAAARTALQDAELDWR
MAV_0989|M.avium_104                -------MTNDVAIIGVGLHPFGRF-DKTAMQMGAEAVQLALADAGVAWK
MSMEG_4778|M.smegmatis_MC2_155      -------MTNDVAIIGVGLHPFGRF-DKPAVQMGAEAIRLALKDAGVEWK
Mflv_2519|M.gilvum_PYR-GCK          MTSS----ANDVAIIGVGLHPFGRF-DKTAMEMGAEAIQSALTDAGVDWK
Mvan_4139|M.vanbaalenii_PYR-1       MTNSSPNAAGEVAIIGVGLHPFGRF-DKTAMQMGAEAIQSALTDAGVEWK
TH_0532|M.thermoresistible__bu      -----MSNENSVAIIGVGLHPFGRF-DKTAMEMGAEAIAAALADAGLEWK
MLBr_02158|M.leprae_Br4923          --------------------------------------------------
MUL_4955|M.ulcerans_Agy99           -----MSASDEIWILGIRMTKFGKHPDLDTVDLAAQAAMSALDDAGVSMA
                                                                                      

Mb1653c|M.bovis_AF2122/97           HVQLVAGADTIRNGYPGFVAGATFAQKLGWTGVPVSSSYAACASGSQALQ
Rv1627c|M.tuberculosis_H37Rv        HVQLVAGADTIRNGYPGFVAGATFAQKLGWTGVPVSSSYAACASGSQALQ
MMAR_2430|M.marinum_M               QIQLVAGADTIRNGYPGFVAGATFAQKLGWNGVPVSSSYAACASGSQALQ
MAB_2619|M.abscessus_ATCC_1997      QIQFVAGADTIRNGYPGFIAGSTFAQKLGWNGVPISSTYAACASGSQALQ
MAV_0989|M.avium_104                DIQFGFGGSYEVS------NPDAVTRLVGLTGITFTNVFNACATAASAIQ
MSMEG_4778|M.smegmatis_MC2_155      DIQFGFGGSYEVS------NPDSVTRLVGLTGITFTNVFNACATSASAIQ
Mflv_2519|M.gilvum_PYR-GCK          DIQFGFGGSYEVS------NPDAVTRLVGLTGITFTNVFNACATAASAIQ
Mvan_4139|M.vanbaalenii_PYR-1       DIQFGFGGSYEVS------NPDAVTRLVGLTGITFTNVFNACATAASAIQ
TH_0532|M.thermoresistible__bu      DIQFGYGGSYEIS------NPDAVTRLVGLTGITFTNVFNACATAASAIQ
MLBr_02158|M.leprae_Br4923          --------------------------------------------------
MUL_4955|M.ulcerans_Agy99           DIGVLAAGNLMAANAG---IGQQLQKQIGQTGIPVYNVANACATGATALR
                                                                                      

Mb1653c|M.bovis_AF2122/97           SARAQILAGFCDVALVIGADTTPKGFFAPVGGERKGDPDWQRFH------
Rv1627c|M.tuberculosis_H37Rv        SARAQILAGFCDVALVIGADTTPKGFFAPVGGERKGDPDWQRFH------
MMAR_2430|M.marinum_M               SARAQILAGFCDVALVVGADTTPKGFFAPVGGERKNDPDWQRFH------
MAB_2619|M.abscessus_ATCC_1997      SARAQILAGFCDVALVIGADTTPKGFFAPVGGERKADPDWQRFH------
MAV_0989|M.avium_104                QTADTIRLGKYDLGIAIGLDKHPRGAFTDDPAKLALPQWYANNG------
MSMEG_4778|M.smegmatis_MC2_155      QTADTIRLGKYDIGVAVGLDKHPRGAFTDDPAKLALPQWYAQNG------
Mflv_2519|M.gilvum_PYR-GCK          QTADTIRLGKYDIGIAIGLDKHPRGAFTDDPAKLALPQWYANNG------
Mvan_4139|M.vanbaalenii_PYR-1       QTADTIRLGKYDIGIAIGLDKHPRGAFTDDPAKLALPQWYAENG------
TH_0532|M.thermoresistible__bu      ETADTIRLGKYDIGIAIGMDKHPRGAFTDDPAKLALPQWYAQNG------
MLBr_02158|M.leprae_Br4923          --------------------------------------------------
MUL_4955|M.ulcerans_Agy99           TAIMAVKAGEVDYGMAVGVEKLSGAGLLGGGGKKKSDADVWTPAGRYGAV
                                                                                      

Mb1653c|M.bovis_AF2122/97           ------LIGATNTVYFALLARRRMDLYG-ATVEDFAQVKVKNSRHGLDNP
Rv1627c|M.tuberculosis_H37Rv        ------LIGATNTVYFALLARRRMDLYG-ATVEDFAQVKVKNSRHGLDNP
MMAR_2430|M.marinum_M               ------LIGATNPVYFALLARRRMDLYG-ATLEDFAQVKVKNSRHGLQNP
MAB_2619|M.abscessus_ATCC_1997      ------LIGATNPVYFALLARRRMDLFG-ATVEDFAQVKVKNSRHGLNNP
MAV_0989|M.avium_104                ------QFVTT--KFFGMKANKYIHDHN-ISQETLARVANKNFRNGALNP
MSMEG_4778|M.smegmatis_MC2_155      ------QFVTT--KFFGMKANKYLHDHN-ISQDTLARVANKNFRNGALNP
Mflv_2519|M.gilvum_PYR-GCK          ------QFVTT--KFFGMKANHYLHKHN-ISEETLARVANKNFRNGVINP
Mvan_4139|M.vanbaalenii_PYR-1       ------QFVTT--KFFGMKANHYIHKHN-ISEETLARVANKNFRNGVLNP
TH_0532|M.thermoresistible__bu      ------QFVTT--KFFGMKANRYLHDHG-ISQETLARVANKNFRNGSLNP
MLBr_02158|M.leprae_Br4923          ----------------------------------MCSVASRFLR------
MUL_4955|M.ulcerans_Agy99           APVDGRIGTETMPGVFAQIGTEYGHKYGGTSFELFAKISEKNHAHSTLNP
                                                                      :. :  :         

Mb1653c|M.bovis_AF2122/97           NARYRKENSIDDVLASPVVSDPLRLLDICATSDGAAALIVASKSFTEKHL
Rv1627c|M.tuberculosis_H37Rv        NARYRKENSIDDVLASPVVSDPLRLLDICATSDGAAALIVASKSFTEKHL
MMAR_2430|M.marinum_M               NARYRKEVSVEDVLASQVVAEPLRLLDICATSDGAAALIVASAKFAREHL
MAB_2619|M.abscessus_ATCC_1997      NARFRKESSVADVLASPVVSDPLRLLDICATSDGAAALIVASADFAKKHL
MAV_0989|M.avium_104                NAFRRKEIPVEEILNSAVLNYPLTQYMFCAPDEGAAAVIMCRADLAHKFT
MSMEG_4778|M.smegmatis_MC2_155      NAFRRKEISVEEILASPTLNHPLTQYMFCAPDEGAAAVIMCRADIAHKFT
Mflv_2519|M.gilvum_PYR-GCK          NAFRRKEISVEEIMASPVLNYPLRQYMFCAPDEGAAAVIMCRADIAHKYT
Mvan_4139|M.vanbaalenii_PYR-1       NAFRRKEISVEEIMASPVLNYPLRQYMFCAPDEGAAAVIMCRGDIAHRFT
TH_0532|M.thermoresistible__bu      NAFRRKEISVEDILNSPVLNYPLTQYMFCAPDEGAAAVIMCRGDIAHRFT
MLBr_02158|M.leprae_Br4923          -------------------TRSLTQCMFCALNKGAFAVIVCLGDIAHKFT
MUL_4955|M.ulcerans_Agy99           LAAYQKRFTLEQIMNDVMIAYPNTRPMCSANCDGAAAAIVCNGETLKSLS
                                                         .      .*  .** * *:.  .  .   

Mb1653c|M.bovis_AF2122/97           GSVAGVPSVRAISTVTPKYPQHLPELPDIATDSTAAVPAPERVFKDQILD
Rv1627c|M.tuberculosis_H37Rv        GSVAGVPSVRAISTVTPKYPQHLPELPDIATDSTAAVPAPERVFKDQILD
MMAR_2430|M.marinum_M               GSLDGVPSVRAVSTVTPRYPQHLPELPDIATDSTAVVPAPERVFKDQILD
MAB_2619|M.abscessus_ATCC_1997      GSVDGVPSVRAVATITPKYPQHLPELPDIATDSTAVVPAPERVFKDQIVD
MAV_0989|M.avium_104                DKPVYVRACEIRTRRYGAYEVHATSAPLDEDASP-TVYAAR---------
MSMEG_4778|M.smegmatis_MC2_155      DKPVYVRASEIRTRTFGAYEVHATSAPPESDAAP-TVYAAR---------
Mflv_2519|M.gilvum_PYR-GCK          DKPVYVRASEIRTRTYGAYEVHATSAPLDEDPSP-TVFAAK---------
Mvan_4139|M.vanbaalenii_PYR-1       DKPVFVRASEIRTRTFGAYEVHATSAPLEEDPSP-TVFAAK---------
TH_0532|M.thermoresistible__bu      DKPVYVRASEIRTRRYGAYEVHATSAPLEEDVAP-TVYAAR---------
MLBr_02158|M.leprae_Br4923          DKTVHVHVTEIRTRRYGAYEVHATFAPLVEDASPKRCTIAK---------
MUL_4955|M.ulcerans_Agy99           ARQR--RRAVKVSASVLTTDPYEPGCQVLPNVNTLTRNAAK---------
                                                :        : .         .     ..         

Mb1653c|M.bovis_AF2122/97           AAYAEAGIGPEDLSLAEVYDLSTAL-ELDWYEHLGLCPKGEAEALLRSGA
Rv1627c|M.tuberculosis_H37Rv        AAYAEAGIGPEDLSLAEVYDLSTAL-ELDWYEHLGLCPKGEAEALLRSGA
MMAR_2430|M.marinum_M               AAYTEAGIGPEDLSLAEVYDLSTAL-ELDWYEHLGLCPKGEAEALLRSGA
MAB_2619|M.abscessus_ATCC_1997      AAYAEAGIGPEDISLAEVYDLSTAL-ELDWYEHLGLCAKGEGEQLLRSGA
MAV_0989|M.avium_104                AAYEAAGIGPEDVDVAQLQDTDAGA-EVIHMAETGLCADGEQEKLLADGA
MSMEG_4778|M.smegmatis_MC2_155      AAYEAAGIGPEDVDIAQLQDTDAGA-EVIHMAETGLCADGDQEKLIAEGA
Mflv_2519|M.gilvum_PYR-GCK          AAYEAAGIGPEDVDIAQLQDTDAGA-EVIHMAETGLCADGEQEKLLADGA
Mvan_4139|M.vanbaalenii_PYR-1       AAYEAAGIGPEDVDIAQLQDTDAGA-EVIHMAETGLCADGEQEKLLADGA
TH_0532|M.thermoresistible__bu      AAYEAAGIGPEDVDIAQLQDTDAGA-EVIHMAETGLCADGEQEKLLAEGA
MLBr_02158|M.leprae_Br4923          AVYRGRQASDLRTSTSPSCRTSVPAPEVIQMDETVLCADGEQEKLASW--
MUL_4955|M.ulcerans_Agy99           TAYEQAGVGPSDLDLVELHDCFATA-ELVHYDNLMLCEQGGAADFFESGA
                                    :.*     .    .        .   *:    .  ** .*    :     

Mb1653c|M.bovis_AF2122/97           TTLGGRVPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQATGRQVAD-A
Rv1627c|M.tuberculosis_H37Rv        TTLGGRVPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQATGRQVAD-A
MMAR_2430|M.marinum_M               TTIGGRVPVNPSGGLACFGEAIPAQAIAQVCELNWQLRGQATGRQVEN-A
MAB_2619|M.abscessus_ATCC_1997      TTVGGRVPVNASGGLACFGEAIPAQAIAQVCELTWQLRGQAGDRQVEG-A
MAV_0989|M.avium_104                TEIHGSMPVNTDGGLIANGEPIGASGLRQVHELVRQLRGEAGERQVPGNP
MSMEG_4778|M.smegmatis_MC2_155      TEIDGSIPVNTDGGLIANGEPIGASGLRQMHELVRQLRGEAGDRQVPGNP
Mflv_2519|M.gilvum_PYR-GCK          TEIHGSIPVNTDGGLIANGEPIGASGLRQVHELVRQLRGEAGDRQVPGAP
Mvan_4139|M.vanbaalenii_PYR-1       TEIHGSIPVNTDGGLIANGEPIGASGLRQVHELVRQLRGQAGDRQVPGQP
TH_0532|M.thermoresistible__bu      TEINGSLPINTDGGLIANGEPIGASGLRQIHELVRQLRGQAGDRQVPGNP
MLBr_02158|M.leprae_Br4923          --------------------------------------------------
MUL_4955|M.ulcerans_Agy99           PWRHGSTPVNVSGGLQSKGHPIAATGIANVWEICHQLRGEAGDRQIDN-A
                                                                                      

Mb1653c|M.bovis_AF2122/97           KVGVTANQGLFGHGSSVIVAR---
Rv1627c|M.tuberculosis_H37Rv        KVGVTANQGLFGHGSSVIVAR---
MMAR_2430|M.marinum_M               RVGVTANQGLFGHGSSVIVAR---
MAB_2619|M.abscessus_ATCC_1997      RVGITANQGLFGNGSSVIVAR---
MAV_0989|M.avium_104                RVGLAQVYGAPGTASATILSL---
MSMEG_4778|M.smegmatis_MC2_155      RVGLAQVYGAPGTASATILSL---
Mflv_2519|M.gilvum_PYR-GCK          RVGLAQVYGAPGTASATILSL---
Mvan_4139|M.vanbaalenii_PYR-1       RVGLAQVYGAPGTASATILSL---
TH_0532|M.thermoresistible__bu      KVGFAQLYGAPGTAAATVLTT---
MLBr_02158|M.leprae_Br4923          ------------------------
MUL_4955|M.ulcerans_Agy99           KVGLAHVIGLGSACGVHILERSAA