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M. tuberculosis H37Rv Rv1627c (-)

annotation: lipid-transfer protein
coordinates: 1828865 - 1830073
length: 402

RMSAPEPVYILGAGMHPWGKWGNDFTEYGVVAARAALRDAGVDWRHVQLVAGADTIRNGYPGFVAGATFA
QKLGWTGVPVSSSYAACASGSQALQSARAQILAGFCDVALVIGADTTPKGFFAPVGGERKGDPDWQRFHL
IGATNTVYFALLARRRMDLYGATVEDFAQVKVKNSRHGLDNPNARYRKENSIDDVLASPVVSDPLRLLDI
CATSDGAAALIVASKSFTEKHLGSVAGVPSVRAISTVTPKYPQHLPELPDIATDSTAAVPAPERVFKDQI
LDAAYAEAGIGPEDLSLAEVYDLSTALELDWYEHLGLCPKGEAEALLRSGATTLGGRVPVNPSGGLACFG
EAIPAQAIAQVCELTWQLRGQATGRQVADAKVGVTANQGLFGHGSSVIVAR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1627c--100% (402)lipid-transfer protein
M. tuberculosis H37RvRv2790cltp16e-5434.94% (415) lipid-transfer protein
M. tuberculosis H37RvRv3540cltp22e-2433.73% (252) lipid-transfer protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1653c-0.0100.00% (402) lipid-transfer protein
M. gilvum PYR-GCKMflv_3568-0.088.69% (398) lipid-transfer protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2619-0.088.41% (397) lipid-transfer protein
M. marinum MMMAR_2430-0.091.25% (400) nonspecific lipid-transfer protein
M. avium 104MAV_3157-0.091.44% (397) lipid-transfer protein
M. smegmatis MC2 155MSMEG_3844-0.091.50% (400) lipid-transfer protein
M. thermoresistible (build 8)TH_2429-0.091.71% (398) PUTATIVE lipid-transfer protein
M. ulcerans Agy99MUL_2143ltp11e-5234.87% (413) lipid-transfer protein
M. vanbaalenii PYR-1Mvan_2862-0.089.70% (398) lipid-transfer protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv1627c|M.tuberculosis_H37Rv        --MRMSAPEPVYILGAGMHPWGKWGN----DFTEYGVVAARAALRDAGVD
Mb1653c|M.bovis_AF2122/97           --MRMSAPEPVYILGAGMHPWGKWGN----DFTEYGVVAARAALRDAGVD
Mflv_3568|M.gilvum_PYR-GCK          -----MSPDPVYILGAGMHPWGKWGR----DFTEYGVVAARAALADAGLD
Mvan_2862|M.vanbaalenii_PYR-1       -----MSPEPVYILGAGMHPWGKWGR----DFTEYGVVAARAALAEAGLH
MSMEG_3844|M.smegmatis_MC2_155      ----MSAPEPVYILGAGMHPWGKWGR----DFTEYGVVAARAALAEAGLD
TH_2429|M.thermoresistible__bu      -----MSPEPVYILGAGMHPWGKWGR----DFTEYGVAAARAALAEAGLD
MMAR_2430|M.marinum_M               ----MSAPEPLYILGAGMHPWGKWGN----DFTEYGVAAARAALREAGLE
MAV_3157|M.avium_104                MTTPSTPPEPLYILGAGMHPWGKWGN----DFTEYGVAAARAALAEAGLD
MAB_2619|M.abscessus_ATCC_1997      ---MSRTPDPVYILGAGMHPWGKWGR----DFTEYGVAAARTALQDAELD
MUL_2143|M.ulcerans_Agy99           --MPNNGSNRVFVIGVGMTKFEKPGRREGWDYPDMARESGTNALNDAGIE
                                           .: ::::*.**  : * *.    *:.: .  :.  ** :* :.

Rv1627c|M.tuberculosis_H37Rv        WRHVQLVAGADTIRNGYPGFVAGATFAQKLGWTGVPVSSSYAACASGSQA
Mb1653c|M.bovis_AF2122/97           WRHVQLVAGADTIRNGYPGFVAGATFAQKLGWTGVPVSSSYAACASGSQA
Mflv_3568|M.gilvum_PYR-GCK          WQQIQLVAGADTIRNGYPGFVAGATFAQKLGWNGIPVTSSYAACASGSQA
Mvan_2862|M.vanbaalenii_PYR-1       WRQIQLVAGADTIRNGYPGFVAGATFAQKLGWNGIPITSSYAACASGSQA
MSMEG_3844|M.smegmatis_MC2_155      WRQIQLVAGADTIRNGYPGFVAGATFAQKLGWNGVPVTSSYAACASGSQA
TH_2429|M.thermoresistible__bu      WRQIQFVAGADTIRNGYPGFVAGSTFAQKLGWNGVPVSSSYAACASGSQA
MMAR_2430|M.marinum_M               WRQIQLVAGADTIRNGYPGFVAGATFAQKLGWNGVPVSSSYAACASGSQA
MAV_3157|M.avium_104                WRQIQLVAGADTIRNGYPGFVAGATFAQKLGWNGVPVSSSYAACASGSQA
MAB_2619|M.abscessus_ATCC_1997      WRQIQFVAGADTIRNGYPGFIAGSTFAQKLGWNGVPISSTYAACASGSQA
MUL_2143|M.ulcerans_Agy99           YREVEHAY----VGYVYGESTSGQRAVYELGMTGIPVVNVNNNCSTGSTA
                                    ::.:: .     :   *    :*   . :** .*:*: .    *::** *

Rv1627c|M.tuberculosis_H37Rv        LQSARAQILAGFCDVALVIGADTTPKGFFAPVGGERKGDPDWQRFHLIGA
Mb1653c|M.bovis_AF2122/97           LQSARAQILAGFCDVALVIGADTTPKGFFAPVGGERKGDPDWQRFHLIGA
Mflv_3568|M.gilvum_PYR-GCK          LQSARAHILAGLCDVALVIGADTTPKGFFAPVGGERKNDPDWQRFHLIGA
Mvan_2862|M.vanbaalenii_PYR-1       LQSARAQILAGLCDVALVIGADTTPKGFFAPVGGERRNDPDWQRFHLIGA
MSMEG_3844|M.smegmatis_MC2_155      LQSARAQILAGFCDVALVVGADTTPKGFFAPVGGERKNDPDWQRFHLIGA
TH_2429|M.thermoresistible__bu      LQSARAQILAGFCDVALVIGADTTPKGFFAPVGGERKNDPDWQRFHLIGA
MMAR_2430|M.marinum_M               LQSARAQILAGFCDVALVVGADTTPKGFFAPVGGERKNDPDWQRFHLIGA
MAV_3157|M.avium_104                LQSARAQILAGFCDVALVIGADTTPKGFFAPVGGERKNDPDWQRFHLIGA
MAB_2619|M.abscessus_ATCC_1997      LQSARAQILAGFCDVALVIGADTTPKGFFAPVGGERKADPDWQRFHLIGA
MUL_2143|M.ulcerans_Agy99           LFLAAQAIRGGLADCTVALGFEKMKPGSLSSSYDDRTQPMDKHVKALAQI
                                    *  *   * .*:.* ::.:* :.   * ::.  .:*    * :   *   

Rv1627c|M.tuberculosis_H37Rv        TNTVY------FALLARRRMDLYGATVEDFAQVKVKNSRHGLDNPNARYR
Mb1653c|M.bovis_AF2122/97           TNTVY------FALLARRRMDLYGATVEDFAQVKVKNSRHGLDNPNARYR
Mflv_3568|M.gilvum_PYR-GCK          TNTVY------FALLARRRMDLYGATTDDFATVKVKNARHGLANPNARYR
Mvan_2862|M.vanbaalenii_PYR-1       TNTVY------FALLARRRMDLYGATVDDFAQVKVKNARHGLHNPNARYR
MSMEG_3844|M.smegmatis_MC2_155      TNTVY------FALLARRRMDLYGATLEDFAQVKVKNARHGLNNPNARYR
TH_2429|M.thermoresistible__bu      TNTVY------FALLARRRMDLYGATAEDFAAVKVKNARHGLHNPYARYR
MMAR_2430|M.marinum_M               TNPVY------FALLARRRMDLYGATLEDFAQVKVKNSRHGLQNPNARYR
MAV_3157|M.avium_104                TNPVY------FALLARRRMDLYGATLEDFAQVKVKNSRHGLQNPNARYR
MAB_2619|M.abscessus_ATCC_1997      TNPVY------FALLARRRMDLFGATVEDFAQVKVKNSRHGLNNPNARFR
MUL_2143|M.ulcerans_Agy99           AEFAFPVAPWMFGAAGREHMQQYGSTAEHFAKIGFKNHKHSVNNPFAQFQ
                                    :: .:      *.  .*.:*: :*:* :.** : .** :*.: ** *:::

Rv1627c|M.tuberculosis_H37Rv        KENSIDDVLASPVVSDPLRLLDICATSDGAAALIVASKSFTEKHLGSVAG
Mb1653c|M.bovis_AF2122/97           KENSIDDVLASPVVSDPLRLLDICATSDGAAALIVASKSFTEKHLGSVAG
Mflv_3568|M.gilvum_PYR-GCK          KEATLDDVHASPVVSDPLRLLDICATSDGAAALIVASKEFTEKHLGSAAG
Mvan_2862|M.vanbaalenii_PYR-1       KEATLDDVAASPVVSDPLRLLDICATSDGAAALIVASKAFTEKHLGSVNG
MSMEG_3844|M.smegmatis_MC2_155      KEASVEDVLASPVVSDPLRLLDICATSDGAAALVVASKSFVEKHLGSVEG
TH_2429|M.thermoresistible__bu      KETSIEDVLASPVVSDPLRLLDICATSDGAAALIVASRSFAEKHLGSVQG
MMAR_2430|M.marinum_M               KEVSVEDVLASQVVAEPLRLLDICATSDGAAALIVASAKFAREHLGSLDG
MAV_3157|M.avium_104                KEVSVEDVLASAVVADPLRLLDICATSDGAAALVVASAKFAREHLGSLAG
MAB_2619|M.abscessus_ATCC_1997      KESSVADVLASPVVSDPLRLLDICATSDGAAALIVASADFAKKHLGSVDG
MUL_2143|M.ulcerans_Agy99           EAYTLDDILASRMIYEPLTKLRCSPTSDGSGAAILASESFVDSHG--LAG
                                    :  :: *: ** :: :**  *  ..****:.* ::**  *. .*     *

Rv1627c|M.tuberculosis_H37Rv        VPSVRAISTVTPKYPQHLPELPDIATDSTAAVPAPERVFKDQILDAAYAE
Mb1653c|M.bovis_AF2122/97           VPSVRAISTVTPKYPQHLPELPDIATDSTAAVPAPERVFKDQILDAAYAE
Mflv_3568|M.gilvum_PYR-GCK          VPSVRAISLQSPQYPQHLPELPDIATDSTAVVPGPDRVFKDQILDAAYTE
Mvan_2862|M.vanbaalenii_PYR-1       VPSVRAISLQSPQYPQHLPELPDIATDSTAVVPAPERVFKDQILDAAYTE
MSMEG_3844|M.smegmatis_MC2_155      VPSVRAISLQSPQYPQHLPELPDIATDSTAVVKAPERVFKDQILDAAYAE
TH_2429|M.thermoresistible__bu      VPSVRAVSTVTPRYPQHLPELPDIATDSTAVVDAPERVFKDQILDAAYAE
MMAR_2430|M.marinum_M               VPSVRAVSTVTPRYPQHLPELPDIATDSTAVVPAPERVFKDQILDAAYTE
MAV_3157|M.avium_104                VPSVRAVSTVTPRYPQHLPELPDIATDSTAAVPAPDRVFKDQIIDAAYAE
MAB_2619|M.abscessus_ATCC_1997      VPSVRAVATITPKYPQHLPELPDIATDSTAVVPAPERVFKDQIVDAAYAE
MUL_2143|M.ulcerans_Agy99           RAVEIVGQAMTTDFASTFDGSAKNLIGYDMNVQAARRVYQ---------Q
                                     .   .    :. :.. :   ..   .    * .. **::         :

Rv1627c|M.tuberculosis_H37Rv        AGIGPEDLSLAEVYDLSTALELDWYEHLGLCPKGEAEALLRSGATTLGGR
Mb1653c|M.bovis_AF2122/97           AGIGPEDLSLAEVYDLSTALELDWYEHLGLCPKGEAEALLRSGATTLGGR
Mflv_3568|M.gilvum_PYR-GCK          AGIAPQDLSLAEVYDLSTALELDWYEHLGLCPRGDAEHLLRSGATTIGGR
Mvan_2862|M.vanbaalenii_PYR-1       AGIGPQDLSLAEVYDLSTALELDWYEHLGLCAKGEAEHLLRSGATTLGGT
MSMEG_3844|M.smegmatis_MC2_155      AGIGPEDLSLAEVYDLSTALELDWYEHLGLCEKGEAEQLLRSGATTIGGR
TH_2429|M.thermoresistible__bu      AGIGPEDLSLAEVYDLSTALELDWYEHLGLCAKGEAEQLLRSGATALGGR
MMAR_2430|M.marinum_M               AGIGPEDLSLAEVYDLSTALELDWYEHLGLCPKGEAEALLRSGATTIGGR
MAV_3157|M.avium_104                AGVAPEDLSLAEVYDLSTALELDWYEHLGLCPKGEAEALLRSGATTLGGR
MAB_2619|M.abscessus_ATCC_1997      AGIGPEDISLAEVYDLSTALELDWYEHLGLCAKGEGEQLLRSGATTVGGR
MUL_2143|M.ulcerans_Agy99           SGLGPEDFQVIELHDCFSANELLLYEALGLCGQGEAPKLIDNGDTTYGGR
                                    :*:.*:*:.: *::*  :* **  ** **** :*:.  *: .* *: ** 

Rv1627c|M.tuberculosis_H37Rv        VPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQATGRQVADAKVGVTAN
Mb1653c|M.bovis_AF2122/97           VPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQATGRQVADAKVGVTAN
Mflv_3568|M.gilvum_PYR-GCK          IPVNPSGGLASFGEAIPAQAIAQVCELTWQLRGQATGRQVEDATVGITAN
Mvan_2862|M.vanbaalenii_PYR-1       IPVNPSGGLASFGEAIPAQAIAQVCELTWQLKGQATGRQVEGATVGITAN
MSMEG_3844|M.smegmatis_MC2_155      IPVNASGGLACFGEAIPAQAIAQVCELTWQLKGQATGRQVEGAKVGITAN
TH_2429|M.thermoresistible__bu      IPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQATGRQVENAKVGITAN
MMAR_2430|M.marinum_M               VPVNPSGGLACFGEAIPAQAIAQVCELNWQLRGQATGRQVENARVGVTAN
MAV_3157|M.avium_104                VPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQATGRQVENATVGITAN
MAB_2619|M.abscessus_ATCC_1997      VPVNASGGLACFGEAIPAQAIAQVCELTWQLRGQAGDRQVEGARVGITAN
MUL_2143|M.ulcerans_Agy99           WVVNPSGGLISKGHPLGATGLAQCCELTWQLRGTADRRQVDNVTAALQHN
                                      **.**** . *..: * .:** ***.***:* *  *** .. ..:  *

Rv1627c|M.tuberculosis_H37Rv        QGLFGHGSSVIVAR---
Mb1653c|M.bovis_AF2122/97           QGLFGHGSSVIVAR---
Mflv_3568|M.gilvum_PYR-GCK          QGLFGHGSSVILAR---
Mvan_2862|M.vanbaalenii_PYR-1       QGLFGHGSSVIVAR---
MSMEG_3844|M.smegmatis_MC2_155      QGLFGHGSSVIVAR---
TH_2429|M.thermoresistible__bu      QGLFGHGSSVIVAR---
MMAR_2430|M.marinum_M               QGLFGHGSSVIVAR---
MAV_3157|M.avium_104                QGLFGHGSSVIVAR---
MAB_2619|M.abscessus_ATCC_1997      QGLFGNGSSVIVAR---
MUL_2143|M.ulcerans_Agy99           IGLGGAAVVTAYQRAER
                                     ** * .  .   *