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M. leprae Br4923 MLBr_02158 (-)

annotation: hypothetical protein MLBr_02158
coordinates: 2561022 - 2561414
length: 130

CSVASRFLRTRSLTQCMFCALNKGAFAVIVCLGDIAHKFTDKTVHVHVTEIRTRRYGAYEVHATFAPLVE
DASPKRCTIAKAVYRGRQASDLRTSTSPSCRTSVPAPEVIQMDETVLCADGEQEKLASW*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02158--100% (130)hypothetical protein MLBr_02158

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2519-7e-2657.02% (114) thiolase
M. tuberculosis H37Rv-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104MAV_0989-1e-2758.77% (114) putative thiolase
M. smegmatis MC2 155MSMEG_4778-1e-2454.39% (114) putative thiolase
M. thermoresistible (build 8)TH_0532-1e-2757.89% (114) putative thiolase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_4139-7e-2657.02% (114) thiolase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2519|M.gilvum_PYR-GCK          MTSS----ANDVAIIGVGLHPFGRFDKTAMEMGAEAIQSALTDAGVDWKD
Mvan_4139|M.vanbaalenii_PYR-1       MTNSSPNAAGEVAIIGVGLHPFGRFDKTAMQMGAEAIQSALTDAGVEWKD
MSMEG_4778|M.smegmatis_MC2_155      MTND-------VAIIGVGLHPFGRFDKPAVQMGAEAIRLALKDAGVEWKD
MAV_0989|M.avium_104                MTND-------VAIIGVGLHPFGRFDKTAMQMGAEAVQLALADAGVAWKD
TH_0532|M.thermoresistible__bu      MSNE-----NSVAIIGVGLHPFGRFDKTAMEMGAEAIAAALADAGLEWKD
MLBr_02158|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_2519|M.gilvum_PYR-GCK          IQFGFGGSYEVSNPDAVTRLVGLTGITFTNVFNACATAASAIQQTADTIR
Mvan_4139|M.vanbaalenii_PYR-1       IQFGFGGSYEVSNPDAVTRLVGLTGITFTNVFNACATAASAIQQTADTIR
MSMEG_4778|M.smegmatis_MC2_155      IQFGFGGSYEVSNPDSVTRLVGLTGITFTNVFNACATSASAIQQTADTIR
MAV_0989|M.avium_104                IQFGFGGSYEVSNPDAVTRLVGLTGITFTNVFNACATAASAIQQTADTIR
TH_0532|M.thermoresistible__bu      IQFGYGGSYEISNPDAVTRLVGLTGITFTNVFNACATAASAIQETADTIR
MLBr_02158|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_2519|M.gilvum_PYR-GCK          LGKYDIGIAIGLDKHPRGAFTDDPAKLALPQWYANNGQFVTTKFFGMKAN
Mvan_4139|M.vanbaalenii_PYR-1       LGKYDIGIAIGLDKHPRGAFTDDPAKLALPQWYAENGQFVTTKFFGMKAN
MSMEG_4778|M.smegmatis_MC2_155      LGKYDIGVAVGLDKHPRGAFTDDPAKLALPQWYAQNGQFVTTKFFGMKAN
MAV_0989|M.avium_104                LGKYDLGIAIGLDKHPRGAFTDDPAKLALPQWYANNGQFVTTKFFGMKAN
TH_0532|M.thermoresistible__bu      LGKYDIGIAIGMDKHPRGAFTDDPAKLALPQWYAQNGQFVTTKFFGMKAN
MLBr_02158|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_2519|M.gilvum_PYR-GCK          HYLHKHNISEETLARVANKNFRNGVINPNAFRRKEISVEEIMASPVLNYP
Mvan_4139|M.vanbaalenii_PYR-1       HYIHKHNISEETLARVANKNFRNGVLNPNAFRRKEISVEEIMASPVLNYP
MSMEG_4778|M.smegmatis_MC2_155      KYLHDHNISQDTLARVANKNFRNGALNPNAFRRKEISVEEILASPTLNHP
MAV_0989|M.avium_104                KYIHDHNISQETLARVANKNFRNGALNPNAFRRKEIPVEEILNSAVLNYP
TH_0532|M.thermoresistible__bu      RYLHDHGISQETLARVANKNFRNGSLNPNAFRRKEISVEDILNSPVLNYP
MLBr_02158|M.leprae_Br4923          ------------MCSVASRFLR-------------------------TRS
                                                :. **.: :*                         . .

Mflv_2519|M.gilvum_PYR-GCK          LRQYMFCAPDEGAAAVIMCRADIAHKYTDKPVYVRASEIRTRTYGAYEVH
Mvan_4139|M.vanbaalenii_PYR-1       LRQYMFCAPDEGAAAVIMCRGDIAHRFTDKPVFVRASEIRTRTFGAYEVH
MSMEG_4778|M.smegmatis_MC2_155      LTQYMFCAPDEGAAAVIMCRADIAHKFTDKPVYVRASEIRTRTFGAYEVH
MAV_0989|M.avium_104                LTQYMFCAPDEGAAAVIMCRADLAHKFTDKPVYVRACEIRTRRYGAYEVH
TH_0532|M.thermoresistible__bu      LTQYMFCAPDEGAAAVIMCRGDIAHRFTDKPVYVRASEIRTRRYGAYEVH
MLBr_02158|M.leprae_Br4923          LTQCMFCALNKGAFAVIVCLGDIAHKFTDKTVHVHVTEIRTRRYGAYEVH
                                    * * **** ::** ***:* .*:**::***.*.*:. ***** :******

Mflv_2519|M.gilvum_PYR-GCK          ATSAPLDEDPSP-TVFAAKAAYEAAGIGPEDVDIAQLQDTDAGA-EVIHM
Mvan_4139|M.vanbaalenii_PYR-1       ATSAPLEEDPSP-TVFAAKAAYEAAGIGPEDVDIAQLQDTDAGA-EVIHM
MSMEG_4778|M.smegmatis_MC2_155      ATSAPPESDAAP-TVYAARAAYEAAGIGPEDVDIAQLQDTDAGA-EVIHM
MAV_0989|M.avium_104                ATSAPLDEDASP-TVYAARAAYEAAGIGPEDVDVAQLQDTDAGA-EVIHM
TH_0532|M.thermoresistible__bu      ATSAPLEEDVAP-TVYAARAAYEAAGIGPEDVDIAQLQDTDAGA-EVIHM
MLBr_02158|M.leprae_Br4923          ATFAPLVEDASPKRCTIAKAVYRGRQASDLRTSTSPSCRTSVPAPEVIQM
                                    ** **  .* :*     *:*.*..   .   .. :    *.. * ***:*

Mflv_2519|M.gilvum_PYR-GCK          AETGLCADGEQEKLLADGATEIHGSIPVNTDGGLIANGEPIGASGLRQVH
Mvan_4139|M.vanbaalenii_PYR-1       AETGLCADGEQEKLLADGATEIHGSIPVNTDGGLIANGEPIGASGLRQVH
MSMEG_4778|M.smegmatis_MC2_155      AETGLCADGDQEKLIAEGATEIDGSIPVNTDGGLIANGEPIGASGLRQMH
MAV_0989|M.avium_104                AETGLCADGEQEKLLADGATEIHGSMPVNTDGGLIANGEPIGASGLRQVH
TH_0532|M.thermoresistible__bu      AETGLCADGEQEKLLAEGATEINGSLPINTDGGLIANGEPIGASGLRQIH
MLBr_02158|M.leprae_Br4923          DETVLCADGEQEKLASW---------------------------------
                                     ** *****:**** :                                  

Mflv_2519|M.gilvum_PYR-GCK          ELVRQLRGEAGDRQVPGAPRVGLAQVYGAPGTASATILSL
Mvan_4139|M.vanbaalenii_PYR-1       ELVRQLRGQAGDRQVPGQPRVGLAQVYGAPGTASATILSL
MSMEG_4778|M.smegmatis_MC2_155      ELVRQLRGEAGDRQVPGNPRVGLAQVYGAPGTASATILSL
MAV_0989|M.avium_104                ELVRQLRGEAGERQVPGNPRVGLAQVYGAPGTASATILSL
TH_0532|M.thermoresistible__bu      ELVRQLRGQAGDRQVPGNPKVGFAQLYGAPGTAAATVLTT
MLBr_02158|M.leprae_Br4923          ----------------------------------------