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M. thermoresistible (build 8) TH_0465 (-)

annotation: conserved hypothetical protein
coordinates: 1002584 - 1003786
length: 401

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0465--100% (401)conserved hypothetical protein
M. thermoresistible (build 8)TH_3043-7e-2633.21% (268) PUTATIVE Triacylglycerol lipase
M. thermoresistible (build 8)TH_2810-4e-0624.62% (264) PUTATIVE Triacylglycerol lipase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1618c-1e-0525.38% (264) hypothetical protein Mb1618c
M. gilvum PYR-GCKMflv_3922-1e-14968.77% (365) secretory lipase
M. tuberculosis H37RvRv1592c-1e-0525.38% (264) hypothetical protein Rv1592c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0965-3e-2237.65% (170) putative lipase
M. marinum MMMAR_1029-4e-2333.75% (240) lipase
M. avium 104MAV_5251-7e-2328.85% (312) secretory lipase family protein
M. smegmatis MC2 155MSMEG_2381-1e-17074.94% (387) hypothetical protein MSMEG_2381
M. ulcerans Agy99MUL_0787-3e-2231.87% (273) lipase
M. vanbaalenii PYR-1Mvan_2478-1e-15570.78% (373) secretory lipase

CLUSTAL 2.0.9 multiple sequence alignment


TH_0465|M.thermoresistible__bu      ----------------MMTTRAGWSRLIFAAVLCAAGLLIAPTPNAVAAA
MSMEG_2381|M.smegmatis_MC2_155      ----------------MLTGVS-----LICAPVCA--LVLAPT-AAWAAE
Mflv_3922|M.gilvum_PYR-GCK          -------------------------------------------------M
Mvan_2478|M.vanbaalenii_PYR-1       ---------------------------------------MGCATTADAAT
MMAR_1029|M.marinum_M               ------------MRAARGRLQSRLQVVVVAMLSCATITVVAPDSARADGG
MUL_0787|M.ulcerans_Agy99           MVIEKRDLFVRGMRAARGRLQSRLQVVVVAMLSCATITVVAPDSARADGG
MAV_5251|M.avium_104                ------------MRDCYRSVMRRVAGVFAALVLMAG-TLTGPAIARADG-
Mb1618c|M.bovis_AF2122/97           -------------------------MVEPGNLAGATGAEWIGRPPHEELQ
Rv1592c|M.tuberculosis_H37Rv        -------------------------MVEPGNLAGATGAEWIGRPPHEELQ
MAB_0965|M.abscessus_ATCC_1997      ---------------------------------------MLVLITAACAR
                                                                                      

TH_0465|M.thermoresistible__bu      PNWSWLDARH---YAGPIPAEP----TLLESVRLDPALSVRG-----AGE
MSMEG_2381|M.smegmatis_MC2_155      PEWSNLDARR---YDAPIPRAG----TLIAAVPLDPALSVAG-----AER
Mflv_3922|M.gilvum_PYR-GCK          PAWSGLDVRG---YDAPIPAPG----ALLDAVPLDPALSVPG-----AGS
Mvan_2478|M.vanbaalenii_PYR-1       PTWSGLDARDASVLEAPVPAPG----ALLETVPLDPALSVAG-----AAG
MMAR_1029|M.marinum_M               FESEGDQSQYDQFYTPPDPLPPGEPGDVIRTEPSRLVLEPSGQLGAIMAT
MUL_0787|M.ulcerans_Agy99           FESEGDQSQYDQFYTPPDPLPPGEPGDVIRTEPSRLALEPSGQLGAIMAT
MAV_5251|M.avium_104                -----DEPQYADFYTPPDPLPPGRPGDLIRTEPSRLVLEPSGQLGAIMAT
Mb1618c|M.bovis_AF2122/97           RKVRPLLPSDDPFYFPPAGYQHAVPGTVLRSRDVELAFMGLIP---QPVT
Rv1592c|M.tuberculosis_H37Rv        RKVRPLLPSDDPFYFPPAGYQHAVPGTVLRSRDVELAFMGLIP---QPVT
MAB_0965|M.abscessus_ATCC_1997      VEAEGVAPQP------PSPPPG----EVLSDVPLSLAPDLDA-----IAD
                                                    *          ::       .             

TH_0465|M.thermoresistible__bu      AYRILYSTVN-QYGQPAVSTAAVFVPHGEAPSGG-WPVVAWAHGTVGLGD
MSMEG_2381|M.smegmatis_MC2_155      AYRILYSTVD-QHDSPAVSTAAVFVPRGQAPEGG-WPVIAWAHGTVGLGD
Mflv_3922|M.gilvum_PYR-GCK          AYRILYSTVD-QHDRPAVSTAAVFLPRTPAPPGG-WPVLAWAHGTVGLGD
Mvan_2478|M.vanbaalenii_PYR-1       AYRILYSTVD-QHGRPAVSTAVVFTPKTPAPEGG-WPVVAWAHGTVGLGD
MMAR_1029|M.marinum_M               GTRIMYRSTD-TRGNPIAVTGTYFEPDNPWPGSGPRPLLSYAPGTVGQGD
MUL_0787|M.ulcerans_Agy99           GTRIMYRSTD-TRGNPIAVTGTYFEPDNPWPGSGPRPLLRYAPGTVGQGD
MAV_5251|M.avium_104                GTRIMYRSTD-TRGNPIAVTGTYFEPYNDWPYGGPRPLISYAPGTQGQGN
Mb1618c|M.bovis_AF2122/97           ATQLLYRTTN-MYGNPEATVTTVIVPAELAPGQT-CPLLSYQCAIDAMSS
Rv1592c|M.tuberculosis_H37Rv        ATQLLYRTTN-MYGNPEATVTTVIVPAELAPGQT-CPLLSYQCAIDAMSS
MAB_0965|M.abscessus_ATCC_1997      GHLIRYMSTSGATGTPTEVTGVVFAPKGEPPQAG-WPIVSVGHGTTGLDD
                                    .  : * :..   . *   . . : *    *     *::    .  . ..

TH_0465|M.thermoresistible__bu      DCTPSALPRS------------ARDDEYLSHWLDQGYAVVATDYVGLGTP
MSMEG_2381|M.smegmatis_MC2_155      DCAPSAQPRS------------ARDNEYLTHWLDQGYAVVGSDYAGLGTP
Mflv_3922|M.gilvum_PYR-GCK          ACTPSARERS------------DRDGDYLSHWLDEGYAVVGSDYTGLGTP
Mvan_2478|M.vanbaalenii_PYR-1       DCTPSALPRS------------GRDDEYLSHWLDQGYVVVGSDYAGLGTP
MMAR_1029|M.marinum_M               QCALSRVFNQGIHWSPWLDLMVNYEETFVATMVARGFAIVMTDYEGLGTP
MUL_0787|M.ulcerans_Agy99           QCALSRVFNQGIHWSPWLDLMVNYEETFVATMVARGFAIVMTDYEGLGTP
MAV_5251|M.avium_104                QCAPSRMFNQGIHYSGGWDIMFNYEELFVATMVARGFAIVMTDYQGLGTP
Mb1618c|M.bovis_AF2122/97           RCFPSYALRRRAKALG---SLTQMELLMISAALAEGWAVSVPDHE--GPK
Rv1592c|M.tuberculosis_H37Rv        RCFPSYALRRRAKALG---SLTQMELLMISAALAEGWAVSVPDHE--GPK
MAB_0965|M.abscessus_ATCC_1997      ECAVSRAPDLR------------GYIWLVRNLSKRGWVVAITDYEGLGVP
                                     *  *                       :     .*:.:  .*:   *  

TH_0465|M.thermoresistible__bu      GLMSYLNSVATAHAVIDSVVAAHQLD---LPLSPKWAIVGQSQGGGAAVN
MSMEG_2381|M.smegmatis_MC2_155      GLMSYLNSVATAHSVVDSVIAMHEMD---LPLSPEWAIVGQSQGGGAAVN
Mflv_3922|M.gilvum_PYR-GCK          GLMSYLNSVTTARGVVDSVLAAHHLD---VDLSPKWAVVGQSQGGGAAVA
Mvan_2478|M.vanbaalenii_PYR-1       GLMSYLNSVTTARGVVDSVLAAHHMD---LPLSPKWAVVGQSQGGGAAVA
MMAR_1029|M.marinum_M               GTHTYVNRLAEGHAVLDAARAAQRLPGTSLDPHGPVAFWGYSQGGGAAAS
MUL_0787|M.ulcerans_Agy99           GTHTYVNRLAEGHAVLDAARAAQRLPGTSLDPHGPVAFWGYSQGGGAAAS
MAV_5251|M.avium_104                PMHTYVGRVAEGQAVLDAARAAMRLPGTSLDPHGPVAFWGYSQGGGATAS
Mb1618c|M.bovis_AF2122/97           GLWG--SPYEPGYRVLDGIRAALNSERVGLSPATPIGLWGYSGGGLASAW
Rv1592c|M.tuberculosis_H37Rv        GLWG--SPYEPGYRVLDGIRAALNSERVGLSPATPIGLWGYSGGGLASAW
MAB_0965|M.abscessus_ATCC_1997      GPHPYLEPRSEGFNVIDAARAAVSLIP---GASTKWAAIGASQGGQATWA
                                               .  *:*.  *               .  * * ** *:  

TH_0465|M.thermoresistible__bu      SARWATEFSAGSGLDYRGVVATGTPANIETVVKMGAPDMQLPPELGPAAN
MSMEG_2381|M.smegmatis_MC2_155      SARWATEFSRGTGLDYRGVVATGTPFNVESIVKQAGPDMALPPNLGPAAN
Mflv_3922|M.gilvum_PYR-GCK          TARWATEFSAGSGLDYRGVVATGTPANVESIVKQAGPDMTVPPELGPMGS
Mvan_2478|M.vanbaalenii_PYR-1       TARWASEFSAGSGLDYRGVVATGTPANVETIVKQAGPDMVVPPELGPMAN
MMAR_1029|M.marinum_M               AAELVSSYAP--ELDVVGTYAGAPPADLVEMLPYMDGNVLVG--------
MUL_0787|M.ulcerans_Agy99           AAELVSSYAP--ELDVVGTYAGAPPADLVEMLPYMDGNVLVG--------
MAV_5251|M.avium_104                AAELAAQYAP--DLHIVGTYAGAPPADLKELLPYADGSALVG--------
Mb1618c|M.bovis_AF2122/97           AAEACGEYAP--DLDIVGAVLGSPVGDLGHTFRRLNGTLLAG--------
Rv1592c|M.tuberculosis_H37Rv        AAEACGEYAP--DLDIVGAVLGSPVGDLGHTFRRLNGTLLAG--------
MAB_0965|M.abscessus_ATCC_1997      ASELAGDYAS--ELEFVGSANLSPAADLTDMATHVGDGRYHWSQLSMMPT
                                    ::.   .::    *.  *    ..  ::                      

TH_0465|M.thermoresistible__bu      SYTAYILAAFREARPDID--VDSVLTPAGLEAVAKAETVCKPQLDSELAG
MSMEG_2381|M.smegmatis_MC2_155      SYTGYILAGFREARPDID--VDSVLTPAGLDAVAKAETLCKPQLDAALAG
Mflv_3922|M.gilvum_PYR-GCK          AYTAYIVAALREARPDLD--LDRVLTPAGREAADRAETLCAADLAGSLTD
Mvan_2478|M.vanbaalenii_PYR-1       AYTAYIVAALREARPDLG--VDRVLTPAGRAAADKAETSCAADLAGALDG
MMAR_1029|M.marinum_M               -AAGYLINGFIYAYPELADAIHERMTPRGEDLLAKTRHQCVQETSFKFMF
MUL_0787|M.ulcerans_Agy99           -AAGCLINGFIYAYPELADAIHERMTPRGEDLLAKTRHQCVEETSFKFMF
MAV_5251|M.avium_104                -VVGYALNSVMAAYPEFADAIRSKMTPRGLAMLESVSRQCVGQTLLDFMF
Mb1618c|M.bovis_AF2122/97           -LPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRMAG
Rv1592c|M.tuberculosis_H37Rv        -LPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVIRMAG
MAB_0965|M.abscessus_ATCC_1997      LLTGLSVT-VPELRPENFLHGSFQDIPRDKALLLGCHNGLDPARSAAIIR
                                       .  :  .    *             .                  :  

TH_0465|M.thermoresistible__bu      MTPAQFFSAPLASVPGLPEALDEYMGTPVTGYDR--PIFLGVGLLDRDVP
MSMEG_2381|M.smegmatis_MC2_155      MTPTDFFRAPLARLPGVDAALDAYMGTPTSGYDR--PIFLGVGMQDRDVP
Mflv_3922|M.gilvum_PYR-GCK          LSVPGFFTAPVTSIPGAADAIDAYMGIPSSGYDR--PVFLGVGMRDRDVP
Mvan_2478|M.vanbaalenii_PYR-1       MTVPGFFTAPVTSIPGAIEAIDDFMGVPASGYDR--PVFLGVGMQDRDVP
MMAR_1029|M.marinum_M               RHLRGYFTKDLDQLVREEPFKTLFEAQRLGRHQPSAPVLIVNNRYDPLVP
MUL_0787|M.ulcerans_Agy99           RHLRGYFTKDLDQLVREEPFKTLFEAQRLGRHQPSAPVLIVNNRYDPLVP
MAV_5251|M.avium_104                RHIQPYFTEDINQLVNEEPFNSLFEAQRIGRYKPNAPVLINSNRYDPLVP
Mb1618c|M.bovis_AF2122/97           RDMGDFLDEPLEDILSTPEVSHVFGDTKLGSAVPTPPVLIVQAVHDYLID
Rv1592c|M.tuberculosis_H37Rv        RDMGDFLDEPLEDILSTPEISHVFGDTKLGSAVPTPPVLIVQAVHDYLID
MAB_0965|M.abscessus_ATCC_1997      LRAKDFHGTSPADPIVFAAALKR-IALPLGPASG--PMFVYAGGADRLIE
                                         :                              *:::     *  : 

TH_0465|M.thermoresistible__bu      PQSTLKFYDQLVAHNQNVELRIYPHE--------DHSGTVLASLPDSTPF
MSMEG_2381|M.smegmatis_MC2_155      PNLTLQLDEALRANGQDVTLKVYPDE--------DHSGTVLASVPDSTPF
Mflv_3922|M.gilvum_PYR-GCK          PGLTLRFADALSANGQDVTLKVYPDA--------DHSGTVLTSVPDSTAF
Mvan_2478|M.vanbaalenii_PYR-1       PSLTLRFSEKLSANGEDVTLKVYPDS--------DHSGTVLASMPDSTRF
MMAR_1029|M.marinum_M               WTQASQLGRDWCAQGAQVEFWTNEEPPFLNKASVNHALTFWVDGERALQW
MUL_0787|M.ulcerans_Agy99           WTQASQLGRDWCAQGAQVEFWTNEEPPFLNKASVNHALTFWVDGERALQW
MAV_5251|M.avium_104                WTAANQLGRDWCAQGADVEFRTNEEPPFLNKLVINHALPMLVDGEPAMQW
Mb1618c|M.bovis_AF2122/97           VSDIDALADSYTAGGANVTYHRDLFS--------EHVSLHPLSAPMTLRW
Rv1592c|M.tuberculosis_H37Rv        VSDIDALADSYTAGGANVTYHRDLFS--------EHVSLHPLSAPMTLRW
MAB_0965|M.abscessus_ATCC_1997      AGWIHAAVRRACALGDTVQEVVSPGK----------GHVDPEGERLGVQW
                                                * .  *                        .      :

TH_0465|M.thermoresistible__bu      LAAAFAD-------------------------------------------
MSMEG_2381|M.smegmatis_MC2_155      LRAAFDRG------------------------------------------
Mflv_3922|M.gilvum_PYR-GCK          LARAFS--------------------------------------------
Mvan_2478|M.vanbaalenii_PYR-1       LARAFS--------------------------------------------
MMAR_1029|M.marinum_M               VADRFNGLPAAPNCGQF---------------------------------
MUL_0787|M.ulcerans_Agy99           VADRFNGRPAAPNCGQF---------------------------------
MAV_5251|M.avium_104                IAARFRGEPTAPNCGQF---------------------------------
Mb1618c|M.bovis_AF2122/97           LTDRFAGKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRKLSRR
Rv1592c|M.tuberculosis_H37Rv        LTDRFAGKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGRKLSRR
MAB_0965|M.abscessus_ATCC_1997      IADRFAGLPAPSNC------------------------------------
                                    :   *                                             

TH_0465|M.thermoresistible__bu      --
MSMEG_2381|M.smegmatis_MC2_155      --
Mflv_3922|M.gilvum_PYR-GCK          --
Mvan_2478|M.vanbaalenii_PYR-1       --
MMAR_1029|M.marinum_M               --
MUL_0787|M.ulcerans_Agy99           --
MAV_5251|M.avium_104                --
Mb1618c|M.bovis_AF2122/97           PL
Rv1592c|M.tuberculosis_H37Rv        PL
MAB_0965|M.abscessus_ATCC_1997      --