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VLVLITAACARVEAEGVAPQPPSPPPGEVLSDVPLSLAPDLDAIADGHLIRYMSTSGATGTPTEVTGVVF APKGEPPQAGWPIVSVGHGTTGLDDECAVSRAPDLRGYIWLVRNLSKRGWVVAITDYEGLGVPGPHPYLE PRSEGFNVIDAARAAVSLIPGASTKWAAIGASQGGQATWAASELAGDYASELEFVGSANLSPAADLTDMA THVGDGRYHWSQLSMMPTLLTGLSVTVPELRPENFLHGSFQDIPRDKALLLGCHNGLDPARSAAIIRLRA KDFHGTSPADPIVFAAALKRIALPLGPASGPMFVYAGGADRLIEAGWIHAAVRRACALGDTVQEVVSPGK GHVDPEGERLGVQWIADRFAGLPAPSNC
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0965 | - | - | 100% (378) | putative lipase |
| M. abscessus ATCC 19977 | MAB_2538c | - | 7e-24 | 29.97% (327) | hypothetical protein MAB_2538c |
| M. abscessus ATCC 19977 | MAB_4351 | - | 2e-14 | 28.92% (249) | secretory lipase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1618c | - | 7e-10 | 25.07% (343) | hypothetical protein Mb1618c |
| M. gilvum PYR-GCK | Mflv_2000 | - | 5e-35 | 31.79% (368) | secretory lipase |
| M. tuberculosis H37Rv | Rv1592c | - | 5e-10 | 25.07% (343) | hypothetical protein Rv1592c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1029 | - | 1e-31 | 34.33% (402) | lipase |
| M. avium 104 | MAV_5251 | - | 2e-23 | 38.64% (220) | secretory lipase family protein |
| M. smegmatis MC2 155 | MSMEG_2381 | - | 4e-21 | 34.32% (169) | hypothetical protein MSMEG_2381 |
| M. thermoresistible (build 8) | TH_3043 | - | 7e-28 | 31.53% (406) | PUTATIVE Triacylglycerol lipase |
| M. ulcerans Agy99 | MUL_0787 | - | 4e-31 | 33.58% (402) | lipase |
| M. vanbaalenii PYR-1 | Mvan_2478 | - | 9e-27 | 29.94% (344) | secretory lipase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2381|M.smegmatis_MC2_155 -----------------------MLTGVSLICAPVCALVLAPTAAWAAEP
Mvan_2478|M.vanbaalenii_PYR-1 -----------------------------MGCA---------TTADAATP
MMAR_1029|M.marinum_M ------------MRAARGRLQSRLQVVVVAMLSCATITVVAPDSARADGG
MUL_0787|M.ulcerans_Agy99 MVIEKRDLFVRGMRAARGRLQSRLQVVVVAMLSCATITVVAPDSARADGG
MAV_5251|M.avium_104 ------------MRDCY-RSVMRRVAGVFAALVLMAGTLTGPAIARADG-
TH_3043|M.thermoresistible__bu --------------------MVRGFAGSVCVLLIVSMGMSSP-LARAEDP
Mb1618c|M.bovis_AF2122/97 -----------------------MVEPGNLAGATGAEWIGRPPHEELQRK
Rv1592c|M.tuberculosis_H37Rv -----------------------MVEPGNLAGATGAEWIGRPPHEELQRK
Mflv_2000|M.gilvum_PYR-GCK -----------------------MTDPIRRVLAAAAAVATVVGCAHATEP
MAB_0965|M.abscessus_ATCC_1997 ---------------------------MLVLITAACARVEAEGVAPQP--
MSMEG_2381|M.smegmatis_MC2_155 -----EWSNLDAR---RYDAPIPRAGTLIAAVPLDPALSVAG-----AER
Mvan_2478|M.vanbaalenii_PYR-1 -----TWSGLDARDASVLEAPVPAPGALLETVPLDPALSVAG-----AAG
MMAR_1029|M.marinum_M FESEGDQSQYDQFYTPPDPLPPGEPGDVIRTEPSRLVLEPSGQLGAIMAT
MUL_0787|M.ulcerans_Agy99 FESEGDQSQYDQFYTPPDPLPPGEPGDVIRTEPSRLALEPSGQLGAIMAT
MAV_5251|M.avium_104 -----DEPQYADFYTPPDPLPPGRPGDLIRTEPSRLVLEPSGQLGAIMAT
TH_3043|M.thermoresistible__bu FT---HEQKYTAFYTPPDPLPPGEPGDLIRTEPARLVLEPSGQLGAIMAT
Mb1618c|M.bovis_AF2122/97 VR--PLLPSDDPFYFPPAGYQHAVPGTVLRSRDVELAFMGLIP---QPVT
Rv1592c|M.tuberculosis_H37Rv VR--PLLPSDDPFYFPPAGYQHAVPGTVLRSRDVELAFMGLIP---QPVT
Mflv_2000|M.gilvum_PYR-GCK ---------------------ELRAGQLLTARPLTTVAALPS------AD
MAB_0965|M.abscessus_ATCC_1997 --------------------PSPPPGEVLSDVPLSLAPDLDA-----IAD
.* :: .
MSMEG_2381|M.smegmatis_MC2_155 AYRILYSTVD-QHDSPAVSTAAVFVPRGQAPEGG-WPVIAWAHGTVGLGD
Mvan_2478|M.vanbaalenii_PYR-1 AYRILYSTVD-QHGRPAVSTAVVFTPKTPAPEGG-WPVVAWAHGTVGLGD
MMAR_1029|M.marinum_M GTRIMYRSTD-TRGNPIAVTGTYFEPDNPWPGSGPRPLLSYAPGTVGQGD
MUL_0787|M.ulcerans_Agy99 GTRIMYRSTD-TRGNPIAVTGTYFEPDNPWPGSGPRPLLRYAPGTVGQGD
MAV_5251|M.avium_104 GTRIMYRSTD-TRGNPIAVTGTYFEPYNDWPYGGPRPLISYAPGTQGQGN
TH_3043|M.thermoresistible__bu GTRIMYRSTD-SRGNPNVVTGMYFEPHNDWPHGGPRPLIAYGPGTQGQGD
Mb1618c|M.bovis_AF2122/97 ATQLLYRTTN-MYGNPEATVTTVIVP-AELAPGQTCPLLSYQCAIDAMSS
Rv1592c|M.tuberculosis_H37Rv ATQLLYRTTN-MYGNPEATVTTVIVP-AELAPGQTCPLLSYQCAIDAMSS
Mflv_2000|M.gilvum_PYR-GCK NRLITYVSDD-SAGEPIVVSGTVSVPKSEPPEGG-WPVINWAHGTTGYAD
MAB_0965|M.abscessus_ATCC_1997 GHLIRYMSTSGATGTPTEVTGVVFAPKGEPPQAG-WPIVSVGHGTTGLDD
: * : . . * * . . *:: . . .
MSMEG_2381|M.smegmatis_MC2_155 DCAPSAQPRS------------ARDNEYLTHWLDQGYAVVGSDYAGLGTP
Mvan_2478|M.vanbaalenii_PYR-1 DCTPSALPRS------------GRDDEYLSHWLDQGYVVVGSDYAGLGTP
MMAR_1029|M.marinum_M QCALSRVFNQGIHWSPWLDLMVNYEETFVATMVARGFAIVMTDYEGLGTP
MUL_0787|M.ulcerans_Agy99 QCALSRVFNQGIHWSPWLDLMVNYEETFVATMVARGFAIVMTDYEGLGTP
MAV_5251|M.avium_104 QCAPSRMFNQGIHYSGGWDIMFNYEELFVATMVARGFAIVMTDYQGLGTP
TH_3043|M.thermoresistible__bu QCAPSRMFSEGIHWTSGADIMFNYEEMFVATMVARGFAIVMTDYEGLGTP
Mb1618c|M.bovis_AF2122/97 RCFPSYALRRR---AKALGSLTQMELLMISAALAEGWAVSVPDHEGP---
Rv1592c|M.tuberculosis_H37Rv RCFPSYALRRR---AKALGSLTQMELLMISAALAEGWAVSVPDHEGP---
Mflv_2000|M.gilvum_PYR-GCK TCAPSAATADG-----LIQDYVQLVRPMLDRWVARGFAVVQTDYQGLGTP
MAB_0965|M.abscessus_ATCC_1997 ECAVSRAPDLR------------GYIWLVRNLSKRGWVVAITDYEGLGVP
* * : .*:.: .*: *
MSMEG_2381|M.smegmatis_MC2_155 GLMSYLNSVATAHSVVDSVIAMHEMD---LPLSPEWAIVGQSQGGGAAVN
Mvan_2478|M.vanbaalenii_PYR-1 GLMSYLNSVTTARGVVDSVLAAHHMD---LPLSPKWAVVGQSQGGGAAVA
MMAR_1029|M.marinum_M GTHTYVNRLAEGHAVLDAARAAQRLPGTSLDPHGPVAFWGYSQGGGAAAS
MUL_0787|M.ulcerans_Agy99 GTHTYVNRLAEGHAVLDAARAAQRLPGTSLDPHGPVAFWGYSQGGGAAAS
MAV_5251|M.avium_104 PMHTYVGRVAEGQAVLDAARAAMRLPGTSLDPHGPVAFWGYSQGGGATAS
TH_3043|M.thermoresistible__bu GVHTYVNRLAQGHALIDAARAAKRLPGTSLDPDGPVAFWGYSQGGGAAAS
Mb1618c|M.bovis_AF2122/97 -KGLWGSPYEPGYRVLDGIRAALNSERVGLSPATPIGLWGYSGGGLASAW
Rv1592c|M.tuberculosis_H37Rv -KGLWGSPYEPGYRVLDGIRAALNSERVGLSPATPIGLWGYSGGGLASAW
Mflv_2000|M.gilvum_PYR-GCK GGHPYVDGVSESNTVTDIVRAARHLDP---GIGTAWVVLGHSQGGQAALF
MAB_0965|M.abscessus_ATCC_1997 GPHPYLEPRSEGFNVIDAARAAVSLIP---GASTKWAAIGASQGGQATWA
: . : * * * * ** *:
MSMEG_2381|M.smegmatis_MC2_155 SARWATEFSRGTGLDYRGVVATGT----PFNVESIVKQAGPDMALPPNLG
Mvan_2478|M.vanbaalenii_PYR-1 TARWASEFSAGSGLDYRGVVATGT----PANVETIVKQAGPDMVVPPELG
MMAR_1029|M.marinum_M AAELVSSYAP--ELDVVGTYAGAP----PADLVEMLPYMDGNVLVG----
MUL_0787|M.ulcerans_Agy99 AAELVSSYAP--ELDVVGTYAGAP----PADLVEMLPYMDGNVLVG----
MAV_5251|M.avium_104 AAELAAQYAP--DLHIVGTYAGAP----PADLKELLPYADGSALVG----
TH_3043|M.thermoresistible__bu AAELASTYGP--ELDVVGTYAGSP----PADLVALLPFADGSVLVG----
Mb1618c|M.bovis_AF2122/97 AAEACGEYAP--DLDIVGAVLGSP----VGDLGHTFRRLNGTLLAG----
Rv1592c|M.tuberculosis_H37Rv AAEACGEYAP--DLDIVGAVLGSP----VGDLGHTFRRLNGTLLAG----
Mflv_2000|M.gilvum_PYR-GCK AAHDGPDRDP--DLRLLGAVAMAPGGVDMGATVDLLRAGDPGVEVAQR--
MAB_0965|M.abscessus_ATCC_1997 ASELAGDYAS--ELEFVGSANLSP----AADLTDMATHVGDGRYHWSQLS
::. * * .. .
MSMEG_2381|M.smegmatis_MC2_155 PAANSYTGYILAGFREARPDID--VDSVLTPAGLDAVAKAETLCKPQLDA
Mvan_2478|M.vanbaalenii_PYR-1 PMANAYTAYIVAALREARPDLG--VDRVLTPAGRAAADKAETSCAADLAG
MMAR_1029|M.marinum_M -----AAGYLINGFIYAYPELADAIHERMTPRGEDLLAKTRHQCVQETSF
MUL_0787|M.ulcerans_Agy99 -----AAGCLINGFIYAYPELADAIHERMTPRGEDLLAKTRHQCVEETSF
MAV_5251|M.avium_104 -----VVGYALNSVMAAYPEFADAIRSKMTPRGLAMLESVSRQCVGQTLL
TH_3043|M.thermoresistible__bu -----ALGYALNGAIAAYPEAEEKIRATLTPRGAHMLDEVKDQCVGETLM
Mb1618c|M.bovis_AF2122/97 -----LPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVI
Rv1592c|M.tuberculosis_H37Rv -----LPALVVAALQHSYPGLARVIKEHANDEGRQLLEQLTEMTTVDAVI
Mflv_2000|M.gilvum_PYR-GCK -----FVPLLVLGAAVVDPSVD--PDQIFTTRARPLLTTARNECLAQLNV
MAB_0965|M.abscessus_ATCC_1997 -----MMPTLLTGLSVTVPELRPENFLHGSFQDIPRDKALLLGCHNGLDP
: . * .
MSMEG_2381|M.smegmatis_MC2_155 ALAGMTPTDFFRAPLARLPGV-DAALDAYMGTPTSGYDR--PIFLGVGMQ
Mvan_2478|M.vanbaalenii_PYR-1 ALDGMTVPGFFTAPVTSIPGA-IEAIDDFMGVPASGYDR--PVFLGVGMQ
MMAR_1029|M.marinum_M KFMFRHLRGYFTKDLDQLVRE-EPFKTLFEAQRLGRHQPSAPVLIVNNRY
MUL_0787|M.ulcerans_Agy99 KFMFRHLRGYFTKDLDQLVRE-EPFKTLFEAQRLGRHQPSAPVLIVNNRY
MAV_5251|M.avium_104 DFMFRHIQPYFTEDINQLVNE-EPFNSLFEAQRIGRYKPNAPVLINSNRY
TH_3043|M.thermoresistible__bu KFAFRHLQPYFNVDIFTAVEE-EPFKSLFELQRLGGLKPEGPVLINANRF
Mb1618c|M.bovis_AF2122/97 RMAGRDMGDFLDEPLEDILST-PEVSHVFGDTKLGSAVPTPPVLIVQAVH
Rv1592c|M.tuberculosis_H37Rv RMAGRDMGDFLDEPLEDILST-PEISHVFGDTKLGSAVPTPPVLIVQAVH
Mflv_2000|M.gilvum_PYR-GCK VPTIPAS-----QVLAPDADV-RGLLAYLDRQDPLQLTPRVPVLIAQGTE
MAB_0965|M.abscessus_ATCC_1997 ARSAAIIRLRAKDFHGTSPADPIVFAAALKRIALPLGPASGPMFVYAGGA
*:::
MSMEG_2381|M.smegmatis_MC2_155 DRDVPPNLTLQLDEALRANGQDVTLKVYPDE--------DHSGTVLASVP
Mvan_2478|M.vanbaalenii_PYR-1 DRDVPPSLTLRFSEKLSANGEDVTLKVYPDS--------DHSGTVLASMP
MMAR_1029|M.marinum_M DPLVPWTQASQLGRDWCAQGAQVEFWTNEEPPFLNKASVNHALTFWVDGE
MUL_0787|M.ulcerans_Agy99 DPLVPWTQASQLGRDWCAQGAQVEFWTNEEPPFLNKASVNHALTFWVDGE
MAV_5251|M.avium_104 DPLVPWTAANQLGRDWCAQGADVEFRTNEEPPFLNKLVINHALPMLVDGE
TH_3043|M.thermoresistible__bu DPLVPWAPAMQMGRDWCAMGADVEARTNEQPPLFNKLIVNHGLPMLVDGE
Mb1618c|M.bovis_AF2122/97 DYLIDVSDIDALADSYTAGGANVTYHRDLFS--------EHVSLHPLSAP
Rv1592c|M.tuberculosis_H37Rv DYLIDVSDIDALADSYTAGGANVTYHRDLFS--------EHVSLHPLSAP
Mflv_2000|M.gilvum_PYR-GCK DVAVNPVGVDKLAKALCGKGVDVDYNTYPGK--------DHRGVIAAAEV
MAB_0965|M.abscessus_ATCC_1997 DRLIEAGWIHAAVRRACALGDTVQEVVSPGK----------GHVDPEGER
* : . * *
MSMEG_2381|M.smegmatis_MC2_155 DSTPFLRAAFDRG-------------------------------------
Mvan_2478|M.vanbaalenii_PYR-1 DSTRFLARAFS---------------------------------------
MMAR_1029|M.marinum_M RALQWVADRFNGLPAAPNCGQF----------------------------
MUL_0787|M.ulcerans_Agy99 RALQWVADRFNGRPAAPNCGQF----------------------------
MAV_5251|M.avium_104 PAMQWIAARFRGEPTAPNCGQF----------------------------
TH_3043|M.thermoresistible__bu PAMQWIADRFKGVPTAPNCGRF----------------------------
Mb1618c|M.bovis_AF2122/97 MTLRWLTDRFAGKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGR
Rv1592c|M.tuberculosis_H37Rv MTLRWLTDRFAGKPLTDHRVRTTWPTIFNPMTYAGMARLAVIAAKVITGR
Mflv_2000|M.gilvum_PYR-GCK TVKDFVDAVMDGRSPENCPR------------------------------
MAB_0965|M.abscessus_ATCC_1997 LGVQWIADRFAGLPAPSNC-------------------------------
:: :
MSMEG_2381|M.smegmatis_MC2_155 -------
Mvan_2478|M.vanbaalenii_PYR-1 -------
MMAR_1029|M.marinum_M -------
MUL_0787|M.ulcerans_Agy99 -------
MAV_5251|M.avium_104 -------
TH_3043|M.thermoresistible__bu -------
Mb1618c|M.bovis_AF2122/97 KLSRRPL
Rv1592c|M.tuberculosis_H37Rv KLSRRPL
Mflv_2000|M.gilvum_PYR-GCK -------
MAB_0965|M.abscessus_ATCC_1997 -------