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MGGARRLKLDGSIPNQLARAADAAVALERNGFDGGWTAEASHDPFLPLLLAAEHTSRLELGTNIAVAFAR NPMIVANVGWDLQTYSKGRLILGLGTQIRPHIEKRFSMPWGHPARRMREFVAALRAIWLAWQDGTKLCFE GEFYTHKIMTPMFTPEPQPYPVPRVFIAAVGEAMTEMCGEVADGHLGHPMVSKRYLTEVSVPALLRGLAR SGRDRSAFEVSCEVMVATGADDAELAAACTATRKQIAFYGSTPAYRKVLEQHGWGDLHPELHRLSKLGEW EAMGGLIDDEMLGAFAVVGPVDTIAGALRNRCEGVVDRVLPIFMAASQECINAALQDFRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1360 | - | - | 100% (340) | PROBABLE OXIDOREDUCTASE |
| M. tuberculosis H37Rv | Rv3520c | - | 3e-17 | 26.91% (301) | coenzyme F420-dependent oxidoreductase |
| M. tuberculosis H37Rv | Rv3192 | - | 3e-13 | 37.04% (108) | hypothetical protein Rv3192 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1395 | - | 0.0 | 100.00% (340) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4326 | - | 1e-120 | 63.55% (321) | putative oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 2e-18 | 26.49% (302) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3914c | - | 7e-87 | 55.16% (281) | oxidoreductase |
| M. marinum M | MMAR_1390 | - | 2e-71 | 46.20% (303) | oxidoreductase |
| M. avium 104 | MAV_4719 | - | 6e-71 | 45.60% (318) | hypothetical protein MAV_4719 |
| M. smegmatis MC2 155 | MSMEG_2256 | - | 1e-133 | 67.37% (334) | hypothetical protein MSMEG_2256 |
| M. thermoresistible (build 8) | TH_1626 | - | 1e-132 | 64.90% (339) | PROBABLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_2486 | - | 7e-70 | 45.54% (303) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_2020 | - | 1e-120 | 62.01% (329) | putative oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1360|M.tuberculosis_H37Rv ---MGGAR--RLKLDGSIPNQLARAADAAVALERNGFDGGWTAEAS-HDP
Mb1395|M.bovis_AF2122/97 ---MGGAR--RLKLDGSIPNQLARAADAAVALERNGFDGGWTAEAS-HDP
MSMEG_2256|M.smegmatis_MC2_155 ---MTDAQNPGVKVDRGISSRLSDVAQTARDLETAGCDGCWTGEIN-HDP
TH_1626|M.thermoresistible__bu ---MGGGAVSGLKIDRGIPSQLDRVPDVARTLERQGYDGCWTGEIN-HDP
Mflv_4326|M.gilvum_PYR-GCK -------------MDAAVVSQLSHVPAAARTLEQRGYDGCWTAEIN-HDP
Mvan_2020|M.vanbaalenii_PYR-1 ---MGAGG--GLKVDAAVVSQLSQVPAAARRLERRGYDGCWTAEIN-HDP
MAB_3914c|M.abscessus_ATCC_199 -----------MLIDVTLTTGLNTMAAEAAEAEESGYAGIWTFEGA-HDP
MMAR_1390|M.marinum_M -----------MRVFTALYG-LADAAERARELRDAGATGVATFEGP-HDV
MUL_2486|M.ulcerans_Agy99 -----------MRVFTALYG-LADAAERARELRDAGASGVATFEGP-HDV
MAV_4719|M.avium_104 -----------MKVQLQVDGSPVRAAASAAEIAATGADGLFTFEGQ-HDV
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDA
: . . * . * * *
Rv1360|M.tuberculosis_H37Rv FLPLLLAAEHTSRLELGTNIAVAFARNPMIVANVGWDLQTYSKGRLILGL
Mb1395|M.bovis_AF2122/97 FLPLLLAAEHTSRLELGTNIAVAFARNPMIVANVGWDLQTYSKGRLILGL
MSMEG_2256|M.smegmatis_MC2_155 FLPLALAAEHTRRIQIGTSIAVAFARNPMTVAHLGWDLQAYSGGRFILGL
TH_1626|M.thermoresistible__bu FLPLLLAAEHTTRLEIGTSIAVAFARNPMTVANIGWDLQAYSRGRFVLGL
Mflv_4326|M.gilvum_PYR-GCK FLPLTLAAEHTERMELGTSIAVAFARNPMSVAQIGWDLQDYSEGRLLLGL
Mvan_2020|M.vanbaalenii_PYR-1 FLPLTLAAEHTHSIELGTSIAVAFARNPMTVAQIGWDLQDYSGGRFILGL
MAB_3914c|M.abscessus_ATCC_199 FLPLLLAAEHTKNVMLGTSIAVAFARNPMLLATIGWDLQAYSGGRFILGL
MMAR_1390|M.marinum_M FAPLTLAATVGG-LDLMTNVAIAFPRNPIHLAHQAYDHQLLSGGRFILGL
MUL_2486|M.ulcerans_Agy99 FAPLTLAATVGG-LDLMTNVAIAFPRNPIHLAHQAYDHQLLSGGRFILGL
MAV_4719|M.avium_104 FFPLLIAAEATG-CELMTNVAIAPPRSPMHLAYAAYDLQLYSGGRFRLGL
MLBr_00348|M.leprae_Br4923 YTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILGL
: ** . : *.:. .*.* * . : * ** ***
Rv1360|M.tuberculosis_H37Rv GTQIRPHIEKRFSMPWGHPARRMREFVAALRAIWLAWQ----DGTKLCFE
Mb1395|M.bovis_AF2122/97 GTQIRPHIEKRFSMPWGHPARRMREFVAALRAIWLAWQ----DGTKLCFE
MSMEG_2256|M.smegmatis_MC2_155 GTQIRPHIEKRFSMPWSHPVRRMREYIAALQAIWTCWR----DGTSLRFE
TH_1626|M.thermoresistible__bu GTQIRPHVERRFSMPWSHPVRRMREFVTALREIWSCWR----DGTRLSFH
Mflv_4326|M.gilvum_PYR-GCK GSQIKPHIEKRFSMPWGRPVARMREFVQALHEIWACWR----DGTRLNFE
Mvan_2020|M.vanbaalenii_PYR-1 GSQIKPHIEKRFSMPWSKPVGRMREFVLALRAIWMSWS----DGSRLEFD
MAB_3914c|M.abscessus_ATCC_199 GTQIKPHITRRFDMPWSSPAARMRDMVLAVRAIWQSWQ----ERGALDYR
MMAR_1390|M.marinum_M GTQVRAQIENRFGAAFDHPVARMTELIAALRAIFAAWN----CGDRLNFR
MUL_2486|M.ulcerans_Agy99 GTQVRAQIENRFGAAFDHPVARMTELIAALRAIFAAWN----CGDRLNFR
MAV_4719|M.avium_104 GSQIKVHVEKRYGSKWEPPAARMAEAISAIKAIFAAWE----GRARLDFR
MLBr_00348|M.leprae_Br4923 GVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHYPLP
* . : :. : * * : : :: ::
Rv1360|M.tuberculosis_H37Rv GEFYTHKIMTPMFTPEP---QPYPVPRVFIAAVGEAMTEMCGEVADGHLG
Mb1395|M.bovis_AF2122/97 GEFYTHKIMTPMFTPEP---QPYPVPRVFIAAVGEAMTEMCGEVADGHLG
MSMEG_2256|M.smegmatis_MC2_155 GEFYTHKIMTPMFTPEP---SPAPFPKVFVAAVGERMTEMCGEAADGLLA
TH_1626|M.thermoresistible__bu GDFYSHTLMTPMFVPEP---QPHGDPRIFLAAVGPEMTRMCGEVADGLLA
Mflv_4326|M.gilvum_PYR-GCK GEFYTHTLMTPMFVPQQ---HAYADPKVFVAAVGDRMTEMCGEVADGLLA
Mvan_2020|M.vanbaalenii_PYR-1 GEFYTHKLMTPMFVPPR---HPYGDPRVFVAAVGDRMTEMCGEVADGLLA
MAB_3914c|M.abscessus_ATCC_199 GDFYQNTLMTPMFMPDPAEVSAFGPPPIWLAGVGTGMTEVAGEVADGFMS
MMAR_1390|M.marinum_M GQFYRHTLMTPTFNPGP---IPFGPPPIYVGALGPRLTRAVAQHADGLLV
MUL_2486|M.ulcerans_Agy99 GQFYRHTLMTPTSNPGP---IPFGPPPIYVGALGPRLTRAVAQHADGLLV
MAV_4719|M.avium_104 GEFYTHTIMAPTFDPGP---NPYGPPPVLLGALGPMMTRTAAEVADGLLV
MLBr_00348|M.leprae_Br4923 LTGAGATGLGKALKPIT--HPLRADIPIMLGAEGPKNVALAAEICDGWLP
. : * : :.. * . .: .** :
Rv1360|M.tuberculosis_H37Rv HPMVSKRYLTEVSVPALLRGLARSG--RDRSAFEVSCEVMVATGADDAEL
Mb1395|M.bovis_AF2122/97 HPMVSKRYLTEVSVPALLRGLARSG--RDRSAFEVSCEVMVATGADDAEL
MSMEG_2256|M.smegmatis_MC2_155 HAFTTRRYLDEVTLPALQRGMDRTG--RSRNDFEVSCPVFLVTGSDEHQM
TH_1626|M.thermoresistible__bu HAFTTRRYLDEVTLPALLDGMNRAG--RRRGDFEVSCPVFVVTGTTETEL
Mflv_4326|M.gilvum_PYR-GCK HAFSTQRYVREVTIPTLERGIARAG--RTRADVVVSSPLFVVTGHDEQEL
Mvan_2020|M.vanbaalenii_PYR-1 HAFSTQRYVREVTIPTLTRGIERAG--RTRADIEVASPLFIVTGLDEQQM
MAB_3914c|M.abscessus_ATCC_199 HPFCTPDYLAQVTRPALGRGALKSG--KALADIQIHHSPMIIIGRDDAEL
MMAR_1390|M.marinum_M MPFGSKRFLHANTMPAVHEGLRAGG--RQAGEFTIIPEIIVSAGDTEADR
MUL_2486|M.ulcerans_Agy99 MPFGSKRFLHANTMPAVHEGLRAGG--RQAGDFTIIPEIIVSAGDTEADR
MAV_4719|M.avium_104 MPFNSARHFAERTLPAIGEGLRRSG--RTLTEFPIIAQAMVAVGRDEADL
MLBr_00348|M.leprae_Br4923 IFFSPR--MADMYNEWLDEGFARTGARRSREDFEICASAQIVVTEDR---
: . . : * * : . : :
Rv1360|M.tuberculosis_H37Rv AAACTATRKQIAFYGS------TPAYRKVLEQHGWGDLHPELHRLSKLGE
Mb1395|M.bovis_AF2122/97 AAACTATRKQIAFYGS------TPAYRKVLEQHGWGDLHPELHRLSKLGE
MSMEG_2256|M.smegmatis_MC2_155 AEAAVATRKQLAFYGS------TPAYRKVLELHGWGDLHTELHRLSLAGE
TH_1626|M.thermoresistible__bu RANAVATRRQLAFYAS------TPAYRSVLDLHGWGDLHTELHALSRRGE
Mflv_4326|M.gilvum_PYR-GCK AANAVATRKQIAFYAS------TPAYRGVLELHGWGDLQTELHRLSRAGE
Mvan_2020|M.vanbaalenii_PYR-1 AAAAVATRKQIAFYAS------TPAYRSVLELHGWGDLQTELHSLSREGD
MAB_3914c|M.abscessus_ATCC_199 ASARAAVRKQLAFYGS------TPAYWPILELHGRAEMGPELKERSKQGE
MMAR_1390|M.marinum_M EQAAAGTRRLLAFYGS------TPAYRPVLAAHGWEDLQPELNALSKQGR
MUL_2486|M.ulcerans_Agy99 EQAAAGTRRLLAFYGS------TPAYRPVLAAHGWEGLQPELNALSKQGR
MAV_4719|M.avium_104 ATAIDGVASLIAFYGS------TPAYLPVLQVEGWDGIQPELNALSKQGR
MLBr_00348|M.leprae_Br4923 AAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQ
. :*:* . * : : * : *: .
Rv1360|M.tuberculosis_H37Rv WEAMGGLIDDEMLGAFAVVGP-VDTIAGALRNRCEGVVDRVLPIFMAAS-
Mb1395|M.bovis_AF2122/97 WEAMGGLIDDEMLGAFAVVGP-VDTIAGALRNRCEGVVDRVLPIFMAAS-
MSMEG_2256|M.smegmatis_MC2_155 WDTMGTLIDDDVLDAFAVVAP-LDELADALRRRCEGAIDRVLPGFPAAVP
TH_1626|M.thermoresistible__bu WDAMGERIDDDVLAAFAVVAP-LDELAGRLRERCAGVIDRVLPAFPAGVP
Mflv_4326|M.gilvum_PYR-GCK WDTMGALIDDTMLAEFAVVAP-VDELVHTIRARCDGLIDRVLVGFPPSID
Mvan_2020|M.vanbaalenii_PYR-1 WDTMGSLIDDGMLAEFAVVAL-VDDVVDKIRARCDGLIDRVLVGFPPSID
MAB_3914c|M.abscessus_ATCC_199 WEAMAALVDDDFVDTAAVTVTDPGQGARELQERYGDLVHRLGFNTPYRPD
MMAR_1390|M.marinum_M WQEMGALIDDTMMHTLAACGT-PADVAAHIRDRVDGISDTVCLYQAAPIG
MUL_2486|M.ulcerans_Agy99 WQEMGALIDDTMMHTLAACGT-PADVAARIRDRVDGISDTVCLYQAAPIG
MAV_4719|M.avium_104 FAQMRGLITDELVARIGIVGT-PEQCAEQIAARFGEHADEVCCYFPGYTP
MLBr_00348|M.leprae_Br4923 KDKAAEIIPNELVDSTMIVGD-VDYVCKQIAAWSAAGVTMMMVSASSVEQ
: : .: : :
Rv1360|M.tuberculosis_H37Rv -QECINAALQDFRR-----------------
Mb1395|M.bovis_AF2122/97 -QECINAALQDFRR-----------------
MSMEG_2256|M.smegmatis_MC2_155 -PATVNAVLDEFRDRP-----PVTRL-----
TH_1626|M.thermoresistible__bu -ETAVTAVLHELRAAPSPTTSPVSTERSRHP
Mflv_4326|M.gilvum_PYR-GCK -EATVVGLVSELQAEETS-------------
Mvan_2020|M.vanbaalenii_PYR-1 -EATVVDLVTDLRTGA---------------
MAB_3914c|M.abscessus_ATCC_199 -RALLPELLAAFPTR----------------
MMAR_1390|M.marinum_M -LRTLAAIIDELR------------------
MUL_2486|M.ulcerans_Agy99 -LRTLAAIIDELR------------------
MAV_4719|M.avium_104 RPADVADLIGALHRVPALP------------
MLBr_00348|M.leprae_Br4923 -VRDLAGLF----------------------
: .