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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_0259 | - | 100% (624) | POSSIBLE BIFUNCTIONAL ENZYME: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD ISOMERASE) + CYCLASE/DEHYDRASE | |
| M. thermoresistible (build 8) | TH_2040 | - | 5e-13 | 29.25% (212) | POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD |
| M. thermoresistible (build 8) | TH_4414 | - | 7e-13 | 28.50% (207) | PUTATIVE fumarylacetoacetate (FAA) hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0964 | - | 0.0 | 74.47% (619) | bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate |
| M. gilvum PYR-GCK | Mflv_4230 | - | 3e-18 | 30.67% (238) | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase |
| M. tuberculosis H37Rv | Rv0939 | - | 0.0 | 74.47% (619) | bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate |
| M. leprae Br4923 | MLBr_01689 | - | 1e-16 | 30.54% (239) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_2020c | - | 5e-41 | 34.56% (298) | bifunctional HHDD isomerase/cyclase/dehydrase |
| M. marinum M | MMAR_4572 | - | 0.0 | 73.39% (620) | bifunctional enzyme: 2-hydroxyhepta-2,4-diene- 1,7-dioate |
| M. avium 104 | MAV_1057 | - | 0.0 | 76.29% (620) | fumarylacetoacetate hydrolase family protein, putative |
| M. smegmatis MC2 155 | MSMEG_6588 | - | 5e-23 | 34.15% (205) | fumarylacetoacetate |
| M. ulcerans Agy99 | MUL_1956 | - | 6e-14 | 30.17% (242) | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase |
| M. vanbaalenii PYR-1 | Mvan_4532 | - | 8e-21 | 30.65% (199) | fumarylacetoacetate (FAA) hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01689|M.leprae_Br4923 --------------------------------------------------
MUL_1956|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4230|M.gilvum_PYR-GCK --------------------------------------------------
Mb0964|M.bovis_AF2122/97 MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAV
Rv0939|M.tuberculosis_H37Rv MKWVTYRSDHGERTGVLSGDAIYAMPPDVSLLDLVGRGADGLRTAGERAV
MMAR_4572|M.marinum_M MKWVTYRSADGERVGVLSDGSIYAMAPGVALLDLIKRGADGLREAGENVL
MAV_1057|M.avium_104 MKWVTYQGDDGERVGVLRDDTIYAMGSGVTLLDLIARGAEGLRHAGEEAQ
TH_0259|M.thermoresistible__bu ------------------------MPPGTELIDLVALGADGLRDAGERAL
MAB_2020c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6588|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4532|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01689|M.leprae_Br4923 --------------------------------------------------
MUL_1956|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4230|M.gilvum_PYR-GCK --------------------------------------------------
Mb0964|M.bovis_AF2122/97 RSPAAVVALDEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDT
Rv0939|M.tuberculosis_H37Rv RSPAAVVALDEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAMGGGRVLMDT
MMAR_4572|M.marinum_M RSPSEVVALDEVTLAAPIPRPPSIRDSLCFLDHMRNCQEAVGGGRVLMDT
MAV_1057|M.avium_104 RSPAATVPAARARLLAPIPRPPSIRDSLCFLDHMRNCQAALGAGRVLADT
TH_0259|M.thermoresistible__bu RDPSEVVPLSDVVLRAPIPRPPAIRDCLCFLDHMRNCQEALGGGRVLKDA
MAB_2020c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6588|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4532|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01689|M.leprae_Br4923 --------------------------------------------------
MUL_1956|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4230|M.gilvum_PYR-GCK --------------------------------------------------
Mb0964|M.bovis_AF2122/97 WYRIPAFYFACPSTVLGPYDDAPTAPGSAWQDFELEIAAVIGTSGKDLTV
Rv0939|M.tuberculosis_H37Rv WYRIPAFYFACPSTVLGPYDDAPTAPGSAWQDFELEIAAVIGTSGKDLTV
MMAR_4572|M.marinum_M WYRIPAFYFACPATVLGPYDDAPMAPGSAWQDFELEIAAVIGTGGQDLSV
MAV_1057|M.avium_104 WYRVPAFYFACPATVLGPYDDAPTAPGSAWQDFELEIAAVIGTGGKDLSV
TH_0259|M.thermoresistible__bu WYRIPAFYFANPSAVFGPYDDVPTAPGSAWQDFELEIAAVIGTGGADLTV
MAB_2020c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6588|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4532|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01689|M.leprae_Br4923 --------------------------------------------------
MUL_1956|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4230|M.gilvum_PYR-GCK --------------------------------------------------
Mb0964|M.bovis_AF2122/97 EQAERSIIGYTIFNDWSARDLQMLEGQLRIGQAKGKDSGITLGPYLVTPD
Rv0939|M.tuberculosis_H37Rv EQAERSIIGYTIFNDWSARDLQMLEGQLRIGQAKGKDSGITLGPYLVTPD
MMAR_4572|M.marinum_M EQAEQSIIGYTIFNDWSARDLQQLEGQLRIGQAKGKDSGVTLGPYLVTAD
MAV_1057|M.avium_104 EQAEQAIIGYTIFNDWSARDLQQLDSQLGIGQAKGKDSGVTLGPYLVTPD
TH_0259|M.thermoresistible__bu AEAEQAIIGYTIFNDWSARDLQSLESQLGIGQAKGKDSGITLGPYLVTPD
MAB_2020c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6588|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4532|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01689|M.leprae_Br4923 --------------------------------------------------
MUL_1956|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4230|M.gilvum_PYR-GCK --------------------------------------------------
Mb0964|M.bovis_AF2122/97 ELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVIAYASRGVTLT
Rv0939|M.tuberculosis_H37Rv ELEPYCRGGKLSLRVIALVNGTVIGSGSTAQMDWSFGEVIAYASRGVTLT
MMAR_4572|M.marinum_M ELQAYRRDGKLSLQVSALVNDTVIGSGSTATMDWTFGEVISYVSRGVMLA
MAV_1057|M.avium_104 ELEPYRRNGKLDLRVTASVNDTVIGSGSTAQMDWTFGEVISYASRGVTLV
TH_0259|M.thermoresistible__bu ELDEFRTDGRLDLTVTALVNGEVIGSGSTAAMDWTFAEVISYASRGVFLH
MAB_2020c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6588|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4532|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01689|M.leprae_Br4923 --------------------------------------------------
MUL_1956|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4230|M.gilvum_PYR-GCK --------------------------------------------------
Mb0964|M.bovis_AF2122/97 PGDVFGSGTVPTCTLVEHLRPP--ESFPGWLHDGDVVTLQVEGLGETRQT
Rv0939|M.tuberculosis_H37Rv PGDVFGSGTVPTCTLVEHLRPP--ESFPGWLHDGDVVTLQVEGLGETRQT
MMAR_4572|M.marinum_M PGDVIGSGTVPTCTLVEHLTNP--DSFPGWLRDGDVVTLEVEGLGQTRQR
MAV_1057|M.avium_104 PGDVIGSGTVPTCTLVEHLDPAALESFPGWLHDGDVVTLRVEGLGETRQT
TH_0259|M.thermoresistible__bu PGEVFGSGTVPTCTLVEHLDMTDLAGFRGWLSDGDEVTLQVQGLGETRQT
MAB_2020c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_6588|M.smegmatis_MC2_155 --------------------------------------MKLRRVRTAADL
Mvan_4532|M.vanbaalenii_PYR-1 --------------------------------------MKLRRVIADGRL
MLBr_01689|M.leprae_Br4923 --------------------------------MFARELAEYPFGELTFTG
MUL_1956|M.ulcerans_Agy99 --------------------------------MTAREIAEDPFGTPNFTG
Mflv_4230|M.gilvum_PYR-GCK ------MRLGRIASPDGVAFVAVEGPPDDPAAAVAREIAEHPFGTPTFTG
Mb0964|M.bovis_AF2122/97 VRTSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTL
Rv0939|M.tuberculosis_H37Rv VRTSGTPFPLALRPNPDAEPDRRGVNPAPTRVPFTRGLHEVADRVWAWTL
MMAR_4572|M.marinum_M VCATPPPQPLAPRVDPNAAPEAARVNPAPPLVPYTRGLHQVADRVWAWTL
MAV_1057|M.avium_104 VRASGAPHPLAARPNPDAPPAAPRVNRAAARVPYTRGLHQVGDRVWAWTL
TH_0259|M.thermoresistible__bu VRHRPAPTLLPPRPNPDAAPAPARVNPAPAKVPYRRGLHQVGENVWAWTL
MAB_2020c|M.abscessus_ATCC_199 ---------------------------MAQDFAFQKGLVPLGGGAHVFLS
MSMEG_6588|M.smegmatis_MC2_155 RVESLDADGNWVPHDDVAPLGGRVFDAEWLAAAADRQLQHSPHLLPFQPV
Mvan_4532|M.vanbaalenii_PYR-1 ELQSLGPDGSWAPAPDPSVLGGPVFDPAWELAAAQRHHGLAGCVLPFQPA
:
MLBr_01689|M.leprae_Br4923 --RSWPLADVRLLAP---MLASKVVCIGKNYADHIVEMGGQTGLASADPV
MUL_1956|M.ulcerans_Agy99 --RSWPLADVRLLAP---ILASKVVCVGKNYTGHIAEMGGQTGPTPADPV
Mflv_4230|M.gilvum_PYR-GCK --RQWPLADVRLLAP---ILASKVVCMGKNYAAHIEEMGGGT---FEDPI
Mb0964|M.bovis_AF2122/97 PDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDA
Rv0939|M.tuberculosis_H37Rv PDGGYGFSNAGLVAGDGASLLVDTLFDLALTREMLAAMKPVTERAPITDA
MMAR_4572|M.marinum_M PDGGFGWSNAGLVAGDGASLLVDTLFDLALTREMLDAMRPITDAAPITDA
MAV_1057|M.avium_104 PDGGYGWSNAGLIAGDGASLLVDTLFDLALTREMLTAMRPITASAPITDA
TH_0259|M.thermoresistible__bu PDGGYGWSNAGLVAGEGASLLVDTLFDLTLTREMLDAMQSITQRAPITDM
MAB_2020c|M.abscessus_ATCC_199 GDEGFGLANAGLVVSDDESLVVDTLYDVRHAREMLDEFGRHTATAPVRYV
MSMEG_6588|M.smegmatis_MC2_155 SFRDFMLYEQHNIDAARGLIRRFHPGLYRATSAFERLTGRPVPQFKPKPL
Mvan_4532|M.vanbaalenii_PYR-1 SFRDFMLYEDHAIDAARGLVRRFHPAQSRAAETVEKLTRKPFPLFKPKPL
: : : :
MLBr_01689|M.leprae_Br4923 IFLKPN------TAIIGPNVPIRLPANASPVHFEG---ELALVVGRSCKD
MUL_1956|M.ulcerans_Agy99 IFLKSN------TAIVGPNVPIRLPANASPVHFEG---ELAIVIGRPCKD
Mflv_4230|M.gilvum_PYR-GCK IFLKPN------TAIIGPYTPIQLPADADPVHFEG---ELAAVIGRPCKD
Mb0964|M.bovis_AF2122/97 LITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQTADLG
Rv0939|M.tuberculosis_H37Rv LITHSNGDHTHGTQLLDRSVRIIAAKGTSEEIEHGPAPEMLARIQTADLG
MMAR_4572|M.marinum_M LITHSNGDHTHGNQLLSPSVRIIAAKGTAEEIAEDTGPTLLTAMQTIDLG
MAV_1057|M.avium_104 VITHSNGDHTHGNQLLDPAVRIIAAHGTAEEIAHGMAPEMLAMAQTANLG
TH_0259|M.thermoresistible__bu VITHCNGDHTHGNQLLDPSVRIIAAKETKDEIDHEMAPSMLALAQTGDLG
MAB_2020c|M.abscessus_ATCC_199 FNTHTDGDHFFGNQVFADDVEIITTEAARALMVQEHADLTAELLGGSSDP
MSMEG_6588|M.smegmatis_MC2_155 FYRQPIYYMSNAQTFVPTGTPVPVPDYSQALDFEL---EIGFVLAAPLFN
Mvan_4532|M.vanbaalenii_PYR-1 FYRQPIYYMSNHLSFVPSGAPVAFPSYSTALDFEL---ELGFVLKAPLFN
. : .. . : . : .
MLBr_01689|M.leprae_Br4923 VPAVQAVDCILGYTIGNDMSAR-DQQRADGQWTRAKGHDTFCPVGPWIVT
MUL_1956|M.ulcerans_Agy99 VSAAQAVDNILGYTIGNDVSAR-DQQKSDGQWTRAKGHDTFCPVGPWIVT
Mflv_4230|M.gilvum_PYR-GCK VPASRAAENILGYTIANDVSAR-DQQKKDGQWMRAKGHDTFCPVGPWIVT
Mb0964|M.bovis_AF2122/97 PVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAH
Rv0939|M.tuberculosis_H37Rv PVATRYLRDRFGHFDFSGIKLRNADLTFDRDLAIELGGRRVDLLNLGPAH
MMAR_4572|M.marinum_M PVATRFMRDRFGHFDFSGIRLRNADQTFDHELTIDVGGRRVDLINLGPAH
MAV_1057|M.avium_104 PVATRYTRERFGHFDFSNITLRNADETFDRSLAVEVGGRRVDVLNLGPAH
TH_0259|M.thermoresistible__bu PIATTYARDRFGHFDFSGITIRNADHTFDKRLDLEVGGRQVTLLNLGPAH
MAB_2020c|M.abscessus_ATCC_199 ASNMHVLAPLAKPFHFNEVRVRPADTTFSGERALRVGKLDVELHELGPAH
MSMEG_6588|M.smegmatis_MC2_155 ATPNEATAAIGAFVVLNDFSARDVQRAEMTSGFGPQKSKHFASSMSDTAV
Mvan_4532|M.vanbaalenii_PYR-1 ASSAEAVDAVGAFVVVNDFSARDVQRAEMATGLGPQKAKHFVSSMSAVAV
. . * : . .
MLBr_01689|M.leprae_Br4923 DLGPLDPADLELR--TAVNGEVKQHSRTSLMIHGIGAIMEWISAVMTLLP
MUL_1956|M.ulcerans_Agy99 DV---DPAGLELR--TEVNGAVKQHARTSLMIHDVGAIVEWISAVMTLLP
Mflv_4230|M.gilvum_PYR-GCK DI---DPSDLEIR--TEVNGELKQHSRTSLMIHDIGAIIEWISSVMTLLP
Mb0964|M.bovis_AF2122/97 TTADSVVHVADAG--VLFAGDLLFIGCTPIVWA--GPIANWVAACDAMIA
Rv0939|M.tuberculosis_H37Rv TTADSVVHVADAG--VLFAGDLLFIGCTPIVWA--GPIANWVAACDAMIA
MMAR_4572|M.marinum_M TAADSVVHVPDAG--VLFAGDLLFIGCTPIVWN--GPIANWIAACDAMIA
MAV_1057|M.avium_104 TAADSVVHVPDAG--VLFGGDLLFIGCTPIVWA--GPIANWVAACDAMIA
TH_0259|M.thermoresistible__bu TAADTVIHIPDAG--VLFGGDLLFIGCTPIVWG--GPIANWIAACDTMLA
MAB_2020c|M.abscessus_ATCC_199 TVGDAVAFLPEHR--VLFSGDLLTRGIVKVVWS--GSIPNWIVALERIRA
MSMEG_6588|M.smegmatis_MC2_155 TADEVLPRIDALTGSVAVNGEIVSTVDSAGMQHSLGEVLAHASRCEPLYP
Mvan_4532|M.vanbaalenii_PYR-1 TADEILPILESLSGSVTINGRTVSTVSSAGPQWTIGDMLAHASRDEKLYP
. . * * : : .
MLBr_01689|M.leprae_Br4923 GDLILTGTPAGVGPVEDGDIVSITVEG-------IGTLTNPVVRKGKS--
MUL_1956|M.ulcerans_Agy99 GDLILTGTPAGVGPIEDGDTVSITIEG-------IDTLTNPVVRKGKS--
Mflv_4230|M.gilvum_PYR-GCK GDLILTGTPEGVGPLEHGDTVSITVEG-------IGTLSNPVVRKGKS--
Mb0964|M.bovis_AF2122/97 LDAPTVVP--GHGPVTGPDGIRAVRG----YLAHIAEQAEAAYRKGLSLP
Rv0939|M.tuberculosis_H37Rv LDAPTVVP--GHGPVTGPDGIRAVRG----YLAHIAEQAEAAYRKGLSLP
MMAR_4572|M.marinum_M LDAPIVVP--GHGPVTDPDGIRAVRG----YFEHVNEQAEAAYRKGLSLA
MAV_1057|M.avium_104 LDAPTVVP--GHGPVTDPDGIRAVRG----YLVHIAEQAEAAYRKGLSWP
TH_0259|M.thermoresistible__bu LDAPTVVP--GHGPITGPEGIHAVRD----YFEYITEQADDAHRRGLSFI
MAB_2020c|M.abscessus_ATCC_199 FGAKIVVP--GHGPLLVDAEVDAAIDRGIAFWSDLHEQANRLYDQGVPAQ
MSMEG_6588|M.smegmatis_MC2_155 GELFGTGTLPGGSGMETGHWLRPGDT--------LTLILDDIGRIEHTIG
Mvan_4532|M.vanbaalenii_PYR-1 GELFATGTLPGGSGMETGHWLRPGDR--------ITLSIEQVGEISHQIT
. . * . : : : :
MLBr_01689|M.leprae_Br4923 --------------------------------------------------
MUL_1956|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4230|M.gilvum_PYR-GCK --------------------------------------------------
Mb0964|M.bovis_AF2122/97 EAVETIDLGEYASWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEW
Rv0939|M.tuberculosis_H37Rv EAVETIDLGEYASWLDSERVVVNVYQRYRELDPDTPRQDLLALLVMQAEW
MMAR_4572|M.marinum_M EAIETVELGDYAAWLDSERIVVNIYQRYRELDPHTPEVERLALLVMQAEW
MAV_1057|M.avium_104 EAADTIDLGEYATWLDAERVVVNVYQRYRELDPHTPQLEVMALLVMQAEW
TH_0259|M.thermoresistible__bu EAADTIDLGPYANWLDAERVVVNVYQRYRELDPDTPQLGVITLLTMQAEW
MAB_2020c|M.abscessus_ATCC_199 DATALIDIAKYPEAMVT--LPIIVTAIYHERNPEIPFQSLTQALESISGQ
MSMEG_6588|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4532|M.vanbaalenii_PYR-1 S-------------------------------------------------
MLBr_01689|M.leprae_Br4923 ---------
MUL_1956|M.ulcerans_Agy99 ---------
Mflv_4230|M.gilvum_PYR-GCK ---------
Mb0964|M.bovis_AF2122/97 AARHCT---
Rv0939|M.tuberculosis_H37Rv AARHCT---
MMAR_4572|M.marinum_M AAKRV----
MAV_1057|M.avium_104 LAKRS----
TH_0259|M.thermoresistible__bu HAKRGAR--
MAB_2020c|M.abscessus_ATCC_199 LAKAAAGPK
MSMEG_6588|M.smegmatis_MC2_155 ---------
Mvan_4532|M.vanbaalenii_PYR-1 ---------