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M. thermoresistible (build 8) TH_4414 (-)

annotation: fumarylacetoacetate (FAA) hydrolase
coordinates: 3111918 - 3112886
length: 323

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4414--100% (323)fumarylacetoacetate (FAA) hydrolase
M. thermoresistible (build 8)TH_2040-2e-2129.09% (220) POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD
M. thermoresistible (build 8)TH_3311-1e-1727.66% (235) PUTATIVE putative HpcE protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3017c-1e-2631.64% (256) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
M. gilvum PYR-GCKMflv_4230-3e-2229.41% (221) 5-carboxymethyl-2-hydroxymuconate Delta-isomerase
M. tuberculosis H37RvRv2993c-1e-2631.64% (256) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
M. leprae Br4923MLBr_01689-4e-2229.41% (221) putative hydrolase
M. abscessus ATCC 19977MAB_3299c-3e-2230.86% (256) hypothetical protein MAB_3299c
M. marinum MMMAR_1718-2e-2130.94% (223) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
M. avium 104MAV_3844-9e-2330.49% (223) 5-carboxymethyl-2-hydroxymuconate delta-isomerase
M. smegmatis MC2 155MSMEG_2382-2e-2129.69% (256) 5-carboxymethyl-2-hydroxymuconate delta-isomerase
M. ulcerans Agy99MUL_1956-1e-1930.04% (223) 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
M. vanbaalenii PYR-1Mvan_2132-3e-2228.96% (221) 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1718|M.marinum_M               --MRLGRIASPDGVAFASIEGELDNPGAMTAREIAEH----PFGTPNFTG
MUL_1956|M.ulcerans_Agy99           ----------------------------MTAREIAED----PFGTPNFTG
MAV_3844|M.avium_104                --MRLGRIASPDGVAFVSIEGELDNPAEMIAREIAEH----PFGTPNFTG
Mb3017c|M.bovis_AF2122/97           ----------------------------MTAREIAEH----PFGTPTFTG
Rv2993c|M.tuberculosis_H37Rv        ----------------------------MTAREIAEH----PFGTPTFTG
MLBr_01689|M.leprae_Br4923          ----------------------------MFARELAEY----PFGELTFTG
Mflv_4230|M.gilvum_PYR-GCK          --MRLGRIASPDGVAFVAVEGPPDDPAAAVAREIAEH----PFGTPTFTG
Mvan_2132|M.vanbaalenii_PYR-1       --MRLGRIASPDGVAFVAIEGPPDDPGGAVAREIAEH----PFGNPTFTG
MAB_3299c|M.abscessus_ATCC_199      --MRLGRIASPDGVAFVSIEGEDGREESAIAREIAEH----PFGTPTFTG
MSMEG_2382|M.smegmatis_MC2_155      --MRLGRIASPDGVAFVSIEG-DGPD--AVCKEIAEH----PFGNPNFTG
TH_4414|M.thermoresistible__bu      VKLASVSVGGRRLLVIEGADGALIDASRLVGRDHLDMNAVLAEGEELLNA
                                                                   ::  :     . *   :..

MMAR_1718|M.marinum_M               RSWPLAD-----------VRLLAPILASKVVCVGKNYTDHIAEMGGQTGP
MUL_1956|M.ulcerans_Agy99           RSWPLAD-----------VRLLAPILASKVVCVGKNYTGHIAEMGGQTGP
MAV_3844|M.avium_104                RSWPLAD-----------VRLLAPILASKVVCVGKNYADHIAEMGEATGP
Mb3017c|M.bovis_AF2122/97           RSWPLAD-----------VRLLAPILASKVVCVGKNYADHIAEMGGRP--
Rv2993c|M.tuberculosis_H37Rv        RSWPLAD-----------VRLLAPILASKVVCVGKNYADHIAEMGGRP--
MLBr_01689|M.leprae_Br4923          RSWPLAD-----------VRLLAPMLASKVVCIGKNYADHIVEMGGQTGL
Mflv_4230|M.gilvum_PYR-GCK          RQWPLAD-----------VRLLAPILASKVVCMGKNYAAHIEEMGGGT--
Mvan_2132|M.vanbaalenii_PYR-1       RQWPLAD-----------VRLLAPILASKVVCMGKNYAAHIEEMGGGT--
MAB_3299c|M.abscessus_ATCC_199      RQWPLAD-----------VRLLAPILASKVVAMGKNYAAHAAEMGGDP--
MSMEG_2382|M.smegmatis_MC2_155      RSWPLAD-----------VRLLAPILASKVIAVGKNYAAHAEEMGGVA--
TH_4414|M.thermoresistible__bu      LRRRVADGVVETVVDPAAVRWLPPSPNPSKIIGVAVNNRSIAQYAHRP--
                                        :**           ** *.*   .. :           : .  .  

MMAR_1718|M.marinum_M               TPADPVIFLKPNTAIVGPNVPIRLPANASPVHFEGELAIVIGRPCKDVSA
MUL_1956|M.ulcerans_Agy99           TPADPVIFLKSNTAIVGPNVPIRLPANASPVHFEGELAIVIGRPCKDVSA
MAV_3844|M.avium_104                VPADPVIFLKPNTAIIGPNVPIRLPANASPVHFEGELAVVIGRPCKDVSA
Mb3017c|M.bovis_AF2122/97           -PADPVIFLKPNTAIIGPNTPIRLPANASPVHFEGELAIVIGRACKDVPA
Rv2993c|M.tuberculosis_H37Rv        -PADPVIFLKPNTAIIGPNTPIRLPANASPVHFEGELAIVIGRACKDVPA
MLBr_01689|M.leprae_Br4923          ASADPVIFLKPNTAIIGPNVPIRLPANASPVHFEGELALVVGRSCKDVPA
Mflv_4230|M.gilvum_PYR-GCK          -FEDPIIFLKPNTAIIGPYTPIQLPADADPVHFEGELAAVIGRPCKDVPA
Mvan_2132|M.vanbaalenii_PYR-1       -FEDPIIFLKPNTAIIGPNTPIQLPADANPVHFEGELAAVIGRPCKDVPA
MAB_3299c|M.abscessus_ATCC_199      -PESPVIFIKPNTSIIGPGLPIQLPPSATEVHHEGELAIVIGRPCKDVPA
MSMEG_2382|M.smegmatis_MC2_155      -PEDPVIFLKPNTAIIGPNVPIQLPADADPVHHEGELAIVIGRPCKDVPA
TH_4414|M.thermoresistible__bu      -PTEPAYFLKPPSALVGHGDPIVVPSEFGLTHPEPELAAVIGRRVRNLTV
                                       .*  *:*. ::::*   ** :*..   .* * *** *:**  :::..

MMAR_1718|M.marinum_M               AQAVDNILGYTIGNDVSARDQQKSD-------------------------
MUL_1956|M.ulcerans_Agy99           AQAVDNILGYTIGNDVSARDQQKSD-------------------------
MAV_3844|M.avium_104                AQAAENILGYTIGNDVSARDQQRSD-------------------------
Mb3017c|M.bovis_AF2122/97           AQAVDNILGYTIGNDVSARDQQQSD-------------------------
Rv2993c|M.tuberculosis_H37Rv        AQAVDNILGYTIGNDVSARDQQQSD-------------------------
MLBr_01689|M.leprae_Br4923          VQAVDCILGYTIGNDMSARDQQRAD-------------------------
Mflv_4230|M.gilvum_PYR-GCK          SRAAENILGYTIANDVSARDQQKKD-------------------------
Mvan_2132|M.vanbaalenii_PYR-1       SRAAENILGYTIANDVSARDQQQKD-------------------------
MAB_3299c|M.abscessus_ATCC_199      ARAAENILGYTIGNDVSARDHQRAD-------------------------
MSMEG_2382|M.smegmatis_MC2_155      ARAAEFILGYTIGNDVSARDQQRKD-------------------------
TH_4414|M.thermoresistible__bu      EGALDAVLGFTIINDITSPSLKDRDSMELTPTVGAIGPVELDWREVRGPE
                                      * : :**:** **::: . :  *                         

MMAR_1718|M.marinum_M               ------GQWTRAKGHDTFCPVGPWIVTDV---DPADLELRTEVNGAVKQH
MUL_1956|M.ulcerans_Agy99           ------GQWTRAKGHDTFCPVGPWIVTDV---DPAGLELRTEVNGAVKQH
MAV_3844|M.avium_104                ------GQWTRAKGHDTFCPVGPWIVTDLNPLDPGDLELRTEVNGEVKQR
Mb3017c|M.bovis_AF2122/97           ------GQWTRAKGHDTFCPVGPWIVTDLAPFDPADLELRTVVNGDVKQH
Rv2993c|M.tuberculosis_H37Rv        ------GQWTRAKGHDTFCPVGPWIVTDLAPFDPADLELRTVVNGDVKQH
MLBr_01689|M.leprae_Br4923          ------GQWTRAKGHDTFCPVGPWIVTDLGPLDPADLELRTAVNGEVKQH
Mflv_4230|M.gilvum_PYR-GCK          ------GQWMRAKGHDTFCPVGPWIVTDI---DPSDLEIRTEVNGELKQH
Mvan_2132|M.vanbaalenii_PYR-1       ------GQWMRAKGHDTFCPVGPWIVTDL---DPSDLEIRTEVNGDVKQR
MAB_3299c|M.abscessus_ATCC_199      ------GQWTRAKGHDTFCPLGPWIVTDL---DPADLEIRTEVNGQVRQR
MSMEG_2382|M.smegmatis_MC2_155      ------GQWMRAKGHDTFCPLGPWIVTDL---DPSDVELRTEVNGQVRQR
TH_4414|M.thermoresistible__bu      DRSVYLTYHARSKGCDSFAPMGPWLVTTEAVGDPNNLDVTCLLDDEVILA
                                              *:** *:*.*:***:**     ** .:::   ::. :   

MMAR_1718|M.marinum_M               ARTSLMIHDVGAIVEWISAVMTLLPGDLILTGTPAGVGPIE---------
MUL_1956|M.ulcerans_Agy99           ARTSLMIHDVGAIVEWISAVMTLLPGDLILTGTPAGVGPIE---------
MAV_3844|M.avium_104                SRTSLLIHDIGSIVEWISAVMTLLPGDLILTGTPAGVGPIE---------
Mb3017c|M.bovis_AF2122/97           ARTSLMIHDIGAIVEWISAIMTLLPGDLILTGTPAGVGPIE---------
Rv2993c|M.tuberculosis_H37Rv        ARTSLMIHDIGAIVEWISAIMTLLPGDLILTGTPAGVGPIE---------
MLBr_01689|M.leprae_Br4923          SRTSLMIHGIGAIMEWISAVMTLLPGDLILTGTPAGVGPVE---------
Mflv_4230|M.gilvum_PYR-GCK          SRTSLMIHDIGAIIEWISSVMTLLPGDLILTGTPEGVGPLE---------
Mvan_2132|M.vanbaalenii_PYR-1       SRTSLMIHDIGAIIEWISAVMTLLPGDLILTGTPEGVGPLE---------
MAB_3299c|M.abscessus_ATCC_199      SRTSLLLHDVGAIVEWVSAVMTLLPGDVILTGTPEGVGPIV---------
MSMEG_2382|M.smegmatis_MC2_155      SRTSLLLHDIGRLVEWTSAVMTLLPGDVILTGTPEGVGPIE---------
TH_4414|M.thermoresistible__bu      DSTSRLTFSVETVLAHLTEYMTLEPGDVVHFGTAVKVAAPARFPTVRHVD
                                      ** : ..:  ::   :  *** ***::  **.  *..           

MMAR_1718|M.marinum_M               ---DGDTVSITIEGIGTLTNPVVRKGKS
MUL_1956|M.ulcerans_Agy99           ---DGDTVSITIEGIDTLTNPVVRKGKS
MAV_3844|M.avium_104                ---DGDTVSITIEGIGTLTNPVVRKGKS
Mb3017c|M.bovis_AF2122/97           ---DGDTVSITIEGIGTLTNPVVRKGKP
Rv2993c|M.tuberculosis_H37Rv        ---DGDTVSITIEGIGTLTNPVVRKGKP
MLBr_01689|M.leprae_Br4923          ---DGDIVSITVEGIGTLTNPVVRKGKS
Mflv_4230|M.gilvum_PYR-GCK          ---HGDTVSITVEGIGTLSNPVVRKGKS
Mvan_2132|M.vanbaalenii_PYR-1       ---HGDSVSITVEGIGTLTNPVVRKGRS
MAB_3299c|M.abscessus_ATCC_199      ---DGDTVSVTIEGIGTLSNPVVRKAK-
MSMEG_2382|M.smegmatis_MC2_155      ---DGDTVSITVEGIGTLTNPVVRKGKK
TH_4414|M.thermoresistible__bu      LSRLEGTLSVEIGGVGRLDNPIKRA---
                                         . :*: : *:. * **: *