For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3747 (-)

annotation: phage integrase family protein
coordinates: 4188467 - 4190422
length: 652

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3747--100% (652)phage integrase family protein
M. thermoresistible (build 8)TH_0846xerC6e-1330.48% (269) PROBABLE INTEGRASE/RECOMBINASE XERC
M. thermoresistible (build 8)TH_2462-9e-1333.50% (206) PUTATIVE phage integrase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2918cxerC8e-1229.72% (286) site-specific tyrosine recombinase XerC
M. gilvum PYR-GCKMflv_4644-1e-10238.15% (637) phage integrase family protein
M. tuberculosis H37RvRv2894cxerC8e-1229.72% (286) site-specific tyrosine recombinase XerC
M. leprae Br4923MLBr_01600xerC1e-1029.70% (266) site-specific tyrosine recombinase XerC
M. abscessus ATCC 19977MAB_3204cxerC2e-1631.68% (303) site-specific tyrosine recombinase XerC
M. marinum MMMAR_1817xerC2e-1231.14% (273) integrase/recombinase XerC
M. avium 104MAV_3746xerC3e-1230.51% (272) site-specific tyrosine recombinase XerC
M. smegmatis MC2 155MSMEG_4156-9e-2124.46% (462) putative transposase
M. ulcerans Agy99MUL_2065xerC2e-1230.77% (273) site-specific tyrosine recombinase XerC
M. vanbaalenii PYR-1Mvan_5498-0.074.49% (635) phage integrase family protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_3747|M.thermoresistible__bu      --------------------------------------------------
Mvan_5498|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_4644|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_1817|M.marinum_M               --------------------------------------------------
MUL_2065|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01600|M.leprae_Br4923          --------------------------------------------------
Mb2918c|M.bovis_AF2122/97           --------------------------------------------------
Rv2894c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_3746|M.avium_104                --------------------------------------------------
MAB_3204c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_4156|M.smegmatis_MC2_155      MTALDPNSTLGLLGRLMAGVRSEFRRDVLEFAADDAVFGGGSCRVTDCGR
                                                                                      

TH_3747|M.thermoresistible__bu      --------------------------MTTPALAMVDPLADPDTVLADYLE
Mvan_5498|M.vanbaalenii_PYR-1       --------------------------MTT---VLVGQPVGADEVVADYLD
Mflv_4644|M.gilvum_PYR-GCK          --------------------------MLP----EHDYAPTPETPAQIYAA
MMAR_1817|M.marinum_M               --------------------------------------------------
MUL_2065|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01600|M.leprae_Br4923          --------------------------------------------------
Mb2918c|M.bovis_AF2122/97           --------------------------------------------------
Rv2894c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_3746|M.avium_104                --------------------------------------------------
MAB_3204c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_4156|M.smegmatis_MC2_155      SARGHGLCQGHHQRWANAGRPDLEEFTVSTDPRWRKHRPNQACRVDGCGY
                                                                                      

TH_3747|M.thermoresistible__bu      YVAALGLSGRSVRARTLIATTFLTSHPDLRDWMTRPAAERLIELRRTGAW
Mvan_5498|M.vanbaalenii_PYR-1       HVATLGLSGRAVRDRIRIARDFTARHRDLHAWMTLPAAERIAEIRDTGAW
Mflv_4644|M.gilvum_PYR-GCK          YLVHLQRRDRGNTAYAQAARSFLRRWPRVQSWADIPLDEQLAANCST--R
MMAR_1817|M.marinum_M               --------------------------------------------------
MUL_2065|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01600|M.leprae_Br4923          --------------------------------------------------
Mb2918c|M.bovis_AF2122/97           --------------------------------------------------
Rv2894c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_3746|M.avium_104                --------------------------------------------------
MAB_3204c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_4156|M.smegmatis_MC2_155      GSARGGLCQLHAQRWERAGRPHLASWLRDPLPVKQPRPGATCRIRHCSLW
                                                                                      

TH_3747|M.thermoresistible__bu      PLLCHLIGRGELRLDLELAAVKNLTGLGRAVEDRDPD-GFAAVRAAGLAL
Mvan_5498|M.vanbaalenii_PYR-1       PLICHTIGTGRLRLDVELAAVKQLTGLGRAVEDRDPS-GFATLRNAGIRL
Mflv_4644|M.gilvum_PYR-GCK          PFVTFLMVSRRLQPGYDYLVHRKLSSLWHELTDSCLQPDLDQFISAALEL
MMAR_1817|M.marinum_M               --------------------------------------------------
MUL_2065|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01600|M.leprae_Br4923          --------------------------------------------------
Mb2918c|M.bovis_AF2122/97           --------------------------------------------------
Rv2894c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_3746|M.avium_104                --------------------------------------------------
MAB_3204c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_4156|M.smegmatis_MC2_155      PQAESPLCHSHTNTWKANGRTDIDGFVTRFESNDTPANETIQLGMLTPQL
                                                                                      

TH_3747|M.thermoresistible__bu      GWTPQWIETV-----LGECLAVLLAWHGGLVSGVSADTVDEFDAALAATQ
Mvan_5498|M.vanbaalenii_PYR-1       GWRSSWVETV-----LGECLAVVLAHHGGMVADLTGDALDDFDATLSRT-
Mflv_4644|M.gilvum_PYR-GCK          GFTERVASAI-----GSQIIARLLIQTGRPLTGLRESDLQELLHACHVRQ
MMAR_1817|M.marinum_M               ------------------------------MPDNSEAILEEFDEYLALQC
MUL_2065|M.ulcerans_Agy99           ------------------------------MPDNSEAILEEFDEYLALQC
MLBr_01600|M.leprae_Br4923          -----------------------------------MAILDEFDEHLALRC
Mb2918c|M.bovis_AF2122/97           ----------------------------------MQAILDEFDEYLALQC
Rv2894c|M.tuberculosis_H37Rv        ----------------------------------MQAILDEFDEYLALQC
MAV_3746|M.avium_104                -------------------------------MPDSEPILEEFDEYLALQC
MAB_3204c|M.abscessus_ATCC_199      ------------------------------MTPQLAAILDEFAEHLALER
MSMEG_4156|M.smegmatis_MC2_155      KLEMQYVLQQRHDDRRGKLTPTVVARVVRLLIDTATTSLLDFDADEWRQR
                                                                          : ::        

TH_3747|M.thermoresistible__bu      SIPATSRRAYRNRIAGLRQMLFQARIVDTPPRRRRWARSYAQRFAEVPMA
Mvan_5498|M.vanbaalenii_PYR-1       AVPPSSRRAYRARLASLRQLLFETAVIDTAPKRRRWARSHEQRFTEVEMP
Mflv_4644|M.gilvum_PYR-GCK          ERTGRGAKHYRSTTHSARQILFHLGILDTQARPAVTALTLEQRMVDVPVA
MMAR_1817|M.marinum_M               GRSAHTRRAYLGDLR-----------------------------------
MUL_2065|M.ulcerans_Agy99           GRSAHTRRAYLGDLR-----------------------------------
MLBr_01600|M.leprae_Br4923          GRSEHTRRAYLGDLR-----------------------------------
Mb2918c|M.bovis_AF2122/97           GRSVHTRRAYLGDLR-----------------------------------
Rv2894c|M.tuberculosis_H37Rv        GRSVHTRRAYLGDLR-----------------------------------
MAV_3746|M.avium_104                GRSAHTRRAYLGDLR-----------------------------------
MAB_3204c|M.abscessus_ATCC_199      GRSVHTQRAYRGDLT-----------------------------------
MSMEG_4156|M.smegmatis_MC2_155      SAVLLNDTRSRGLLLYAHSTVLDLAEAGG------WEAEYPRDVWRMHRL
                                                                                      

TH_3747|M.thermoresistible__bu      DAIRATLLRYVTVRASVLRPKSVESLINDLLPFADYLTTAHPEVTSLEDL
Mvan_5498|M.vanbaalenii_PYR-1       DPIRQTLLRYIGVRAAVLRPKSVESLINDLLPFAEYLTAHHPDLTSLRGL
Mflv_4644|M.gilvum_PYR-GCK          --LRPAFVAYLNRKYATCVPKTVSSLATRLAHFGRYLAAADPSLTSLNQL
MMAR_1817|M.marinum_M               -----SLLDYLAGRG--ADLRALS-----LPVLRSWLATAAGAGAARTTL
MUL_2065|M.ulcerans_Agy99           -----SLLDYLAGRG--ADLRALS-----LPVLRSWLATAAGAGAARTTL
MLBr_01600|M.leprae_Br4923          -----SLLTHLEGRG--SRLDQLS-----LPVLRSWLATAAGAGAARTTL
Mb2918c|M.bovis_AF2122/97           -----SLFAFLADRG--SSLDALT-----LSVLRSWLAATAGAGAARTTL
Rv2894c|M.tuberculosis_H37Rv        -----SLFAFLADRG--SSLDALT-----LSVLRSWLAATAGAGAARTTL
MAV_3746|M.avium_104                -----SLLAFAGERG--TGLDGLS-----LPLLRSWLSAAAAGGVARTTL
MAB_3204c|M.abscessus_ATCC_199      -----LLFDHLSASNPEATLADLS-----LPVLRSWLGAQARQGAARSTV
MSMEG_4156|M.smegmatis_MC2_155      GYEGHYTLRFDRIPQPWLREPAKRWIRLRLSRGLNLEAGGGRPLLAIARF
                                           . .                   *               :   .

TH_3747|M.thermoresistible__bu      DRN-HIEGFLVWNRTRTWRGQRAASGAGRIISKAVIQSTVLSVRNLLDDI
Mvan_5498|M.vanbaalenii_PYR-1       DRS-CIEGYLKWNRTRGWRGQRAAAGAGRTVSAAVAQSAVLSLRNLLDDI
Mflv_4644|M.gilvum_PYR-GCK          DRRRHIEPFITSLTTATN------SVTGEPITVADRIRCIHAVGNFLAEI
MMAR_1817|M.marinum_M               ARR------------------------------------TSAVKAFTAWA
MUL_2065|M.ulcerans_Agy99           ARR------------------------------------TSAVKAFTAWA
MLBr_01600|M.leprae_Br4923          ARR------------------------------------ISAVKAFTAWA
Mb2918c|M.bovis_AF2122/97           ARR------------------------------------TSAVKAFTAWA
Rv2894c|M.tuberculosis_H37Rv        ARR------------------------------------TSAVKAFTAWA
MAV_3746|M.avium_104                ARR------------------------------------TSAVKAFTAWA
MAB_3204c|M.abscessus_ATCC_199      ARR------------------------------------TSAVKIFTAWA
MSMEG_4156|M.smegmatis_MC2_155      GRFLAEVDIEDISRIDRELLERYLAHLNREYSPQRRGAHIGLLNGFFAAI
                                     *                                        :  :    

TH_3747|M.thermoresistible__bu      TEWGWEQAPPRRLVFAVDVPKLDQPLPRALPPDIDVAVMNAVSGLDDS--
Mvan_5498|M.vanbaalenii_PYR-1       TAWGWAQAPPRRLVFAADVPKLDQPLPRALAPDVDAAVMNAVAHLQDP--
Mflv_4644|M.gilvum_PYR-GCK          TEWGWDDAPPRRLIFRTDLPRPPRCLPRYLPVDSDRKLTAALAKSPYR--
MMAR_1817|M.marinum_M               VRRGLLATDP---AARLQVPKAHRTLPAVLRQDQALAAMTAAKSGAQQGD
MUL_2065|M.ulcerans_Agy99           VRRGLLATDP---AARLQVPKAHRTLPAVLRQDQALAAMTAAKSSAQQGD
MLBr_01600|M.leprae_Br4923          KWRGQLAADP---AARLQVPRAYRTLPAVLRQDQALQIMAAAKSGAEQGD
Mb2918c|M.bovis_AF2122/97           VRRGLLAGDP---AARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQGD
Rv2894c|M.tuberculosis_H37Rv        VRRGLLAGDP---AARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQGD
MAV_3746|M.avium_104                VRRGLLTADP---AARLQVPKTHRTLPAVLRQDQALGAMAAAKNGAAQGD
MAB_3204c|M.abscessus_ATCC_199      TRRGLLPTDP---AIRLQQPKSRRTLPAVLRQDQAAAAMEAAHSGAEQDD
MSMEG_4156|M.smegmatis_MC2_155      RQHCWATGLP---ATAMFFAEDHPKRGEHLPRALAEHVMTQLEHRDNLDR
                                             *         ..        *                    

TH_3747|M.thermoresistible__bu      ----FARIGLTVLRGAGLRVGELLDLELGSVIDYGPAGTWLKVPLGKLAT
Mvan_5498|M.vanbaalenii_PYR-1       ----FARIGLTVLRGAGLRAGELLDLELGSIIDYGPAGTWLKVPLGKLAT
Mflv_4644|M.gilvum_PYR-GCK          ----LAADALLVQRACGLRIGELLDLELDCIHEIPGQGSWLKVPLGKLNS
MMAR_1817|M.marinum_M               PLALRDRLIVELLYATGIRVSELCGLDIDDVD----TGHRLVRVLGKGNK
MUL_2065|M.ulcerans_Agy99           PLALRDRLIVELLYATGIRVSELRGLDIDDVD----TGHRLVRVLGKGNK
MLBr_01600|M.leprae_Br4923          PLALRDRLIVEMLYATGIRVSELCGLDIDDVD----TRHRLVRVLGKGNK
Mb2918c|M.bovis_AF2122/97           PLALRDRLIVELLYATGIRVSELCGLDVDDID----TGHRLVRVLGKGNK
Rv2894c|M.tuberculosis_H37Rv        PLALRDRLIVELLYATGIRVSELCGLDVDDID----TGHRLVRVLGKGNK
MAV_3746|M.avium_104                PIALRDRLIVEMLYATGIRVSELCGLDIDDVD----TGRRLVRVLGKGNK
MAB_3204c|M.abscessus_ATCC_199      PMALRDRLIVEMLYATGIRVSELCGLDIDDID----RPRKVLRVLGKGDK
MSMEG_4156|M.smegmatis_MC2_155      FNNPVYRLITVILMRCGLRITDALRLRGDCVTTDANGAPYLRYFNHKMKR
                                               :    *:*  :   *  . :         :     *   

TH_3747|M.thermoresistible__bu      ERMVPLSVATIAALDEWTTGRGICRPLPHPRTGALTDFLFVAHGRRLS--
Mvan_5498|M.vanbaalenii_PYR-1       ERMVPLSAATLAALDEWVALRGTHRPLPHPRTGVLTDFLFTRHGRRLG--
Mflv_4644|M.gilvum_PYR-GCK          ERMIPVDDEVLTLVDRITTTRSSGRPMIHPRTGAPADFLFTHHGKRLS--
MMAR_1817|M.marinum_M               QRTAPFGQPAAEALQAWLADGR--PALATAESGP--ALLLGARGRRLD--
MUL_2065|M.ulcerans_Agy99           QRTAPFGQPAAEALQAWLADGR--PALATAESGP--ALLLGARGRRLD--
MLBr_01600|M.leprae_Br4923          QRTAPFGVPAADALRGWLDDGR--PALVTVESGP--ALLLGSRGRRLD--
Mb2918c|M.bovis_AF2122/97           QRTVPFGQPAADALHAWLVDGR--RALVTAESGH--ALLLGARGRRLD--
Rv2894c|M.tuberculosis_H37Rv        QRTVPFGQPAADALHAWLVDGR--RALVTAESGH--ALLLGARGRRLD--
MAV_3746|M.avium_104                QRSVPFGAPAGEALHAWLADGR--PALANAESGP--ALLLGARGRRLD--
MAB_3204c|M.abscessus_ATCC_199      ERTVPFGDPAADALSAWLDRGR--PHLAVPASGA--ALLLGARGRRVD--
MSMEG_4156|M.smegmatis_MC2_155      DALVPIAPDLVDMIGYQR-------RLVSERWPDGTALLFPRPTKNIDGQ
                                    :   *.       :            :          :*:    :.:.  

TH_3747|M.thermoresistible__bu      ----QTRLRNGLIAAVETCGLRGAGGAPLVVTPHQLRHTWATELANAGMG
Mvan_5498|M.vanbaalenii_PYR-1       ----YTRLRNGLLTAAESAGLHRPDGGVLMVTPHQLRHTWATELANAGMS
Mflv_4644|M.gilvum_PYR-GCK          ----QNAVREELNRAAQAASLG-------HITPHQLRHTYATALINAGVS
MMAR_1817|M.marinum_M               ----VRQARTVVHQTVAAVDGAP------DMGPHGLRHSAATHLLEGGAD
MUL_2065|M.ulcerans_Agy99           ----VRQARTVVHQTIAAVDGAP------DMGPHGLRHSAATHLLEGGAD
MLBr_01600|M.leprae_Br4923          ----VRQARTVVHQTVAVVAGAP------DMGPHGLRHSAATHLLEGGAD
Mb2918c|M.bovis_AF2122/97           ----VRQARTAVHQTVAAVDGAP------DMGPHGLRHSAATHLLEGGAD
Rv2894c|M.tuberculosis_H37Rv        ----VRQARTAVHQTVAAVDGAP------DMGPHGLRHSAATHLLEGGAD
MAV_3746|M.avium_104                ----VRQARTVVHQTIAAVSGAP------DMGPHGLRHSAATHLLEGGAD
MAB_3204c|M.abscessus_ATCC_199      ----PRQVRTVVHQTMSAVPGAP------DIGPHGLRHSAATHLLEGGAD
MSMEG_4156|M.smegmatis_MC2_155      IPLAIPTYREALHRWLAVCDIRDEHSDPVHLTPHQWRHTLGTRLINRDVP
                                            *  :                  : **  **: .* * : .  

TH_3747|M.thermoresistible__bu      LQALMALLGHVTPQMTLRYATLASPTLRDAYDQAMGKMR---RRFTLTPV
Mvan_5498|M.vanbaalenii_PYR-1       LQALMSLLGHVTPQMTIRYATLASPTLRAAYDEAMGKMR---RQFTLTPV
Mflv_4644|M.gilvum_PYR-GCK          LQALMALLGHVSTQMSLRYAHLFDHTVRTEYERALDLAKSHIGALPKTAV
MMAR_1817|M.marinum_M               LRVVQELLGHSSLATTQLYTHVAVSRLRAVHDQAHPRA------------
MUL_2065|M.ulcerans_Agy99           LRVVQELLGHSSLATTQLYTHVAVSRLRAVHDQAHPRA------------
MLBr_01600|M.leprae_Br4923          LRVVQELLGHSSLATTQLYTHVAVSRLRVVHDQAHPRA------------
Mb2918c|M.bovis_AF2122/97           LRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA------------
Rv2894c|M.tuberculosis_H37Rv        LRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA------------
MAV_3746|M.avium_104                LRVVQELLGHSSLATTQLYTHVAVSRLRAVHDQAHPRA------------
MAB_3204c|M.abscessus_ATCC_199      LRVVQELLGHSTLATTQLYTHVTVARLRAVHDQAHPRA------------
MSMEG_4156|M.smegmatis_MC2_155      QEVVRRILDHDSPQMTAHYARLHDTTVRRAWEAAR-KVDSHGREVNLDPD
                                     ..:  :*.* :   :  *: :    :*   : *                

TH_3747|M.thermoresistible__bu      GKPIVPDA-VIWLGSEMLKTRVAHGYCSRHESAGACPYANICETCDNFVT
Mvan_5498|M.vanbaalenii_PYR-1       GKPILPDK-VGWLHSEMLKTRVAHGYCARHESAGACPYANICETCDNYIT
Mflv_4644|M.gilvum_PYR-GCK          GLPITDITGTGWKDTPAIKSRLAGGYCLRAPAQGSCPYANICEHCPSFHT
MMAR_1817|M.marinum_M               --------------------------------------------------
MUL_2065|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01600|M.leprae_Br4923          --------------------------------------------------
Mb2918c|M.bovis_AF2122/97           --------------------------------------------------
Rv2894c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_3746|M.avium_104                --------------------------------------------------
MAB_3204c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_4156|M.smegmatis_MC2_155      GP--LAEAAWAKQRLGRATQALPNGYCG-LPVQQSCPHANACLTCPMFLT
                                                                                      

TH_3747|M.thermoresistible__bu      GPEFRDALEAQRTDVEALEVDARDRGWPDEAARHHRVADALTDHLQRLDR
Mvan_5498|M.vanbaalenii_PYR-1       APEFRDTLTNQLADVQDLRTDAECRGWTDEAARHDRVAHALTDHLHRLDH
Mflv_4644|M.gilvum_PYR-GCK          DSTHLAVLAAQRIDAQDLAADAEKRGWIDEAERHHNLVSRLDALITGSAS
MMAR_1817|M.marinum_M               --------------------------------------------------
MUL_2065|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01600|M.leprae_Br4923          --------------------------------------------------
Mb2918c|M.bovis_AF2122/97           --------------------------------------------------
Rv2894c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_3746|M.avium_104                --------------------------------------------------
MAB_3204c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_4156|M.smegmatis_MC2_155      TQEFLPQHRTQREQTLHLITAAEARGHQRLAEMNRQVLGNLDAIITSLDT
                                                                                      

TH_3747|M.thermoresistible__bu      -----------
Mvan_5498|M.vanbaalenii_PYR-1       -----------
Mflv_4644|M.gilvum_PYR-GCK          A----------
MMAR_1817|M.marinum_M               -----------
MUL_2065|M.ulcerans_Agy99           -----------
MLBr_01600|M.leprae_Br4923          -----------
Mb2918c|M.bovis_AF2122/97           -----------
Rv2894c|M.tuberculosis_H37Rv        -----------
MAV_3746|M.avium_104                -----------
MAB_3204c|M.abscessus_ATCC_199      -----------
MSMEG_4156|M.smegmatis_MC2_155      PTDPKAAEHAS