For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MDVIRWARRLAVVAGTAAAVTTPGLLSAHVPMVSAEPCPDVEVVFARGTGEPPGIGSVGGLFVDALRFPG WRQVTRGLRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3724A | cut5a | - | 100% (80) | PROBABLE CUTINASE PRECURSOR |
| M. tuberculosis H37Rv | Rv3452 | cut4 | 5e-12 | 55.22% (67) | cutinase precursor CUT4 |
| M. tuberculosis H37Rv | Rv3451 | cut3 | 2e-11 | 56.14% (57) | cutinase precursor CUT3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3751 | cut5 | 3e-34 | 100.00% (67) | cutinase precursor CUT5 |
| M. gilvum PYR-GCK | Mflv_3373 | - | 1e-11 | 48.39% (62) | cutinase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3763 | - | 4e-10 | 47.54% (61) | cutinase cut2 precursor |
| M. marinum M | MMAR_5251 | cut5 | 5e-17 | 66.13% (62) | cutinase, Cut5 |
| M. avium 104 | MAV_4394 | - | 6e-14 | 56.06% (66) | serine esterase, cutinase family protein |
| M. smegmatis MC2 155 | MSMEG_1526 | - | 5e-13 | 46.97% (66) | cutinase |
| M. thermoresistible (build 8) | TH_0238 | - | 1e-13 | 55.77% (52) | serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_4327 | cut5 | 7e-18 | 66.13% (62) | cutinase, Cut5 |
| M. vanbaalenii PYR-1 | Mvan_5793 | - | 4e-14 | 55.93% (59) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3724A|M.tuberculosis_H37Rv --------MDVIRWARRLAVVAGTAAAVTTPGLLSAHVPMVSAEPCPDVE
Mb3751|M.bovis_AF2122/97 --------MDVIRWARRLAVVAGTAAAVTTPGLLSAHVPMVSAEPCPDVE
MMAR_5251|M.marinum_M --------MRNATWTRRLAVGAATAVTALVG--WGIRVPFAAAEPCPDVE
MUL_4327|M.ulcerans_Agy99 --------MRNATWTRRLAVGAATAVTALVG--GGIRVPFVAAEPCPDVE
Mvan_5793|M.vanbaalenii_PYR-1 --------MKMSRVAGIAGAVALGACSAVTG----LGAPSAAAQPCPDVE
TH_0238|M.thermoresistible__bu -----LSRIGSAVGAALTTASLITGTVITSTVVAGTAVPAAAAQPCPDVQ
Mflv_3373|M.gilvum_PYR-GCK --------MRSKRLRAVAGAVFVATAASVQT---VAGTPAAAADPCPDVE
MSMEG_1526|M.smegmatis_MC2_155 MVEHSSSPQLLKWLSAVVIVAATAVALVVAPTVTTRGLPMAGAAPCADVE
MAB_3763|M.abscessus_ATCC_1997 MTLQPNPRPASKLLTAAARAAVVSVAAIMLTTGLAVVIPATASAACPNVE
MAV_4394|M.avium_104 MKTHRIGR-----LLGLGSSALITAAGLLGAP---AAVPVASADDCPDVE
* ..: *.:*:
Rv3724A|M.tuberculosis_H37Rv VVFARGTGEPPGIGSVGGLFVDALR-------------------------
Mb3751|M.bovis_AF2122/97 VVFARGTGEPPGIGSVGGLFVDALRSQVGAKSLGVYAVNYPASNDFAS-S
MMAR_5251|M.marinum_M VLFARGTGEPPGIGGIGGSFVAALRSDIGAKSLAVYAVDYPASSDFSS-S
MUL_4327|M.ulcerans_Agy99 VLFARGTGEPPGIGGIGGSFVAALRSDIGAKSSAVYAIDYPASSDFSS-S
Mvan_5793|M.vanbaalenii_PYR-1 VVFARGTSEPPGVGGVGQAFVDALRAQAAPRTVGVYAVNYPAANNFTDRA
TH_0238|M.thermoresistible__bu VVFARGTGEPPGVGPTGQAFIDALRPRVGDRSLDVYAVNYPAIDVWNT--
Mflv_3373|M.gilvum_PYR-GCK VIWARGTGAPAGLGWLGTAFVDSLRAKVGGRSVGAYGVNYPASFDFDA--
MSMEG_1526|M.smegmatis_MC2_155 VIFARGRTEPAGVGTLGNAFVNALRPKVK-KSMNVYAVKYPADTEVDV--
MAB_3763|M.abscessus_ATCC_1997 VSFARGRSQPPGLGNIGDAFVSALRNRVK--NLSVYAVRYDAN---TDVG
MAV_4394|M.avium_104 VIFARGTNEPPGMGRVGDAFVESLRQQTSGLNIDTYGVNYAASKLQLHGG
* :*** *.*:* * *: :**
Rv3724A|M.tuberculosis_H37Rv -----------------------FPGWRQVTRGLRR--------------
Mb3751|M.bovis_AF2122/97 DFPKTVIDGIRDAGSHIQSMAMSCPQTRQVLGGYSQGAAVAGYVTSAVVP
MMAR_5251|M.marinum_M DFPRTVIEGIRDASSHIESMAAKCPATREVLGGYSQGAAVAGYVTSASVP
MUL_4327|M.ulcerans_Agy99 DFPRTVIDGIRDASSHIESMAAKCPATREVLGGYSQGAAVAGYVTSASVP
Mvan_5793|M.vanbaalenii_PYR-1 AFAGTVIDGIRDASNRLQAMSVNCPNTRLVLGGFSQGAVVSGFTTSDTVP
TH_0238|M.thermoresistible__bu -----GIDGIRDAGAHVVRMAEQCPDTRLVLGGFSQGAAVMGFVTSAEVP
Mflv_3373|M.gilvum_PYR-GCK ----SAPMGAADAAGRVQWMADNCPDTRLVLGGNSQGAGVIDLITLDATP
MSMEG_1526|M.smegmatis_MC2_155 --------GANDMSNRIKYMMDNCPNTRLVIGGYSLGAAVADVVLAVPFT
MAB_3763|M.abscessus_ATCC_1997 G-------GANDLSAHLQQTANNCPDTKLVVGGYSLGAGVVDTALGVPGP
MAV_4394|M.avium_104 D-------GANDTINRIKQAVQKCPNTKIVLGGYSQGASVMDIVAGVP--
* : * *
Rv3724A|M.tuberculosis_H37Rv --------------------------------------------------
Mb3751|M.bovis_AF2122/97 -PAVPVQAVPAPMAPEVANHVAAVTLFGAPSAQFLGQYGAPPIAIGPLYQ
MMAR_5251|M.marinum_M -PGVPAAAVPKPMAPDIADHVAAVTLFGTPSEQFLQHYGAPPITIGPLYQ
MUL_4327|M.ulcerans_Agy99 -PGVPAAAVPKPMAPDIADYVAAVTLFGTPSEQFLQHYGAPPITIGPLYQ
Mvan_5793|M.vanbaalenii_PYR-1 -SSVPAAAAPTPLPPKVAEHVAAVVLFGAPSGSFMEKYGAPAVTVGPLYA
TH_0238|M.thermoresistible__bu -AGVDPATVPKPLDPDIAEHVAAVVLFGMPNARAMNFLGTPPVVIGPLYE
Mflv_3373|M.gilvum_PYR-GCK -RGR---FTPTPLAPHLSDRVAAVAVFGNPLRDLPG--GGPLSQVSGVFG
MSMEG_1526|M.smegmatis_MC2_155 -AFG----FKNPLPAGADQHIAAVALFGNG-----AAWVGPITNFSPVYN
MAB_3763|M.abscessus_ATCC_1997 VQIGNLFSFDNPVPPEVGDHIRAIVTFGNIVN----RFA-PVQSLAGAYG
MAV_4394|M.avium_104 --IGGIN-WGSSITPDLASHVAAVATFGDVAD----RAGGTLPSQSALLG
Rv3724A|M.tuberculosis_H37Rv --------------------------------------------------
Mb3751|M.bovis_AF2122/97 PKTLQLCADGDSICG--------DGNSPVAHGLYAVNG-MVGQGANFAAS
MMAR_5251|M.marinum_M PRTVELCASGDPVCS--------GGNDAAAHALYAVNG-MTGQGADFAAH
MUL_4327|M.ulcerans_Agy99 PRTIELCASGDPVCS--------GGNDAAAHALYAVNG-MTGQGADFAAH
Mvan_5793|M.vanbaalenii_PYR-1 DRTVELCAAGDSICDGAP-----NGGPNLAHALYPVNG-MVGQGASYAAG
TH_0238|M.thermoresistible__bu DKTVKLCAVDDPVCS--------NGMNFAAHNTYATNAAMVDQGAAFAAD
Mflv_3373|M.gilvum_PYR-GCK SRSIDLCGLDDPFCS--------SGLNFPAHFSYIKNG-MVEEATNFVAG
MSMEG_1526|M.smegmatis_MC2_155 DRTIELCHGADPICNPADPNTWQNNWPDHLAGAYISGG-MVNQAADFVAS
MAB_3763|M.abscessus_ATCC_1997 DRVLDLCNDGDPVCMD-------GNQDTWKSHTS-YPPALINQAADFAAA
MAV_4394|M.avium_104 SKAIDLCNPNDPICHA-------GPGNEWSGHTEGYVPVYTTQAAAFVAS
Rv3724A|M.tuberculosis_H37Rv --------------------------------------------------
Mb3751|M.bovis_AF2122/97 RL------------------------------------------------
MMAR_5251|M.marinum_M HL------------------------------------------------
MUL_4327|M.ulcerans_Agy99 HL------------------------------------------------
Mvan_5793|M.vanbaalenii_PYR-1 RL------------------------------------------------
TH_0238|M.thermoresistible__bu RLGVASDKPLPTPSSGQNFGN-----------------------------
Mflv_3373|M.gilvum_PYR-GCK RLQ-----------------------------------------------
MSMEG_1526|M.smegmatis_MC2_155 KL------------------------------------------------
MAB_3763|M.abscessus_ATCC_1997 RVN-----------------------------------------------
MAV_4394|M.avium_104 KLMGAGQSVPGYGPSVPGAGPQSPGYGQQSPVYGQTPPGSGPSIHDNAPG
Rv3724A|M.tuberculosis_H37Rv --------------------
Mb3751|M.bovis_AF2122/97 --------------------
MMAR_5251|M.marinum_M --------------------
MUL_4327|M.ulcerans_Agy99 --------------------
Mvan_5793|M.vanbaalenii_PYR-1 --------------------
TH_0238|M.thermoresistible__bu --------------------
Mflv_3373|M.gilvum_PYR-GCK --------------------
MSMEG_1526|M.smegmatis_MC2_155 --------------------
MAB_3763|M.abscessus_ATCC_1997 --------------------
MAV_4394|M.avium_104 PGTAPAPAVPSTPPSQAPLV