For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VEHSSSPQLLKWLSAVVIVAATAVALVVAPTVTTRGLPMAGAAPCADVEVIFARGRTEPAGVGTLGNAFV NALRPKVKKSMNVYAVKYPADTEVDVGANDMSNRIKYMMDNCPNTRLVIGGYSLGAAVADVVLAVPFTAF GFKNPLPAGADQHIAAVALFGNGAAWVGPITNFSPVYNDRTIELCHGADPICNPADPNTWQNNWPDHLAG AYISGGMVNQAADFVASKL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1526 | - | - | 100% (230) | cutinase |
| M. smegmatis MC2 155 | MSMEG_1528 | - | 2e-50 | 48.42% (221) | cutinase |
| M. smegmatis MC2 155 | MSMEG_6354 | - | 5e-35 | 39.83% (231) | serine esterase, cutinase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2323 | cut2 | 3e-86 | 69.95% (213) | cutinase CUT2 |
| M. gilvum PYR-GCK | Mflv_4967 | - | 3e-76 | 66.32% (193) | cutinase |
| M. tuberculosis H37Rv | Rv2301 | cut2 | 3e-86 | 69.95% (213) | cutinase CUT2 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3763 | - | 2e-45 | 40.18% (224) | cutinase cut2 precursor |
| M. marinum M | MMAR_2908 | - | 6e-88 | 69.72% (218) | cutinase precursor |
| M. avium 104 | MAV_2759 | - | 1e-79 | 73.63% (182) | serine esterase, cutinase family protein |
| M. thermoresistible (build 8) | TH_3765 | - | 3e-82 | 65.58% (215) | PUTATIVE Cutinase |
| M. ulcerans Agy99 | MUL_0856 | cut3 | 6e-43 | 42.99% (221) | cutinase precursor, Cut3 |
| M. vanbaalenii PYR-1 | Mvan_1439 | - | 1e-78 | 65.60% (218) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2323|M.bovis_AF2122/97 MNDLLTRR----------LLTMGAAAAMLAAVLLLTPITVPAGYPGAVAP
Rv2301|M.tuberculosis_H37Rv MNDLLTRR----------LLTMGAAAAMLAAVLLLTPITVPAGYPGAVAP
MMAR_2908|M.marinum_M MRALFARR----------SVQFGVGAVAVAAALTIAAAVLPPGTPGAAPS
MAV_2759|M.avium_104 --------------------------------------------------
MSMEG_1526|M.smegmatis_MC2_155 MVEHSSSP----------QLLKWLSAVVIVAATAVALVVAPTVTTRGLPM
Mflv_4967|M.gilvum_PYR-GCK MIRQLRNL----------RVPYLVVALLFGAASLILP-----------PA
Mvan_1439|M.vanbaalenii_PYR-1 MIRQLRKF----------PVLSALAALLSTAAALVAP-----------PL
TH_3765|M.thermoresistible__bu MVGTMGEVNSDLELPGTRRTVALLTAALFLAAGLVTGSAVSPASAPLAPV
MAB_3763|M.abscessus_ATCC_1997 MTLQPNPR----------PASKLLTAAARAAVVSVAAIMLTTGLAVVIPA
MUL_0856|M.ulcerans_Agy99 MNKHPLAV----------LAGALVTATGLLAAPSITG--------TAIPS
Mb2323|M.bovis_AF2122/97 ATAA-CPDAEVVFARGRFEPPGIGTVGNAFVSALRSKVN-KNVGVYAVKY
Rv2301|M.tuberculosis_H37Rv ATAA-CPDAEVVFARGRFEPPGIGTVGNAFVSALRSKVN-KNVGVYAVKY
MMAR_2908|M.marinum_M TDAANCPQVEVVFARGRFESPGPGVLGNAFISSLSSKVGGRSMGSYAVKY
MAV_2759|M.avium_104 --------MQVVFARGRNESPGPGVLGNAFISALRSRVN-RTVGVYAVQY
MSMEG_1526|M.smegmatis_MC2_155 AGAAPCADVEVIFARGRTEPAGVGTLGNAFVNALRPKVK-KSMNVYAVKY
Mflv_4967|M.gilvum_PYR-GCK ASAQACPQAELIFARGRIESPGAGVIGNALASALRNKTG-RDIDLYAVKY
Mvan_1439|M.vanbaalenii_PYR-1 ASAQACPEVELIFARGRIESPGAGQIGNALVSALRSKTG-KSVDLYAVKY
TH_3765|M.thermoresistible__bu AQAAPCPDVEVIFARGRVESPGPGIIGNAFVNSLRSKTD-KNVSLYAVQY
MAB_3763|M.abscessus_ATCC_1997 TASAACPNVEVSFARGRSQPPGLGNIGDAFVSALRNRVK--NLSVYAVRY
MUL_0856|M.ulcerans_Agy99 ASAADCPDAEVVFPRGTSEPPGIGRVGEAFVDSLRQQTG-KNIGVYAVNY
:: *.** :..* * :*:*: .:* :. :. ***.*
Mb2323|M.bovis_AF2122/97 PAD---NQIDVGANDMSAHIQSMANSCPNTRLVPGGYSLGAAVTDVVLAV
Rv2301|M.tuberculosis_H37Rv PAD---NQIDVGANDMSAHIQSMANSCPNTRLVPGGYSLGAAVTDVVLAV
MMAR_2908|M.marinum_M PAD---TEVDIGANDMSGHIQYMVNSCPDTRLVLGGYSLGAAVTDVVLAV
MAV_2759|M.avium_104 PAD---TEVAQGANDMSRHIQDMVNSCPDTRLVLGGYSLGAAVTDVVLAA
MSMEG_1526|M.smegmatis_MC2_155 PAD---TEVDVGANDMSNRIKYMMDNCPNTRLVIGGYSLGAAVADVVLAV
Mflv_4967|M.gilvum_PYR-GCK PAD---TEVDIGANDMSQRIQYMARNCPDTRLVLGGYSLGAAVTDIVIAV
Mvan_1439|M.vanbaalenii_PYR-1 PAD---TEVDLGANDMSQRIQYMAGNCPDTRLVLGGYSLGAAVTDVVVAV
TH_3765|M.thermoresistible__bu PAD---YEIDIGANDMSRRIQHMAATCPDTRLVLGGYSLGAAVTDVVLAV
MAB_3763|M.abscessus_ATCC_1997 DAN---TDVGGGANDLSAHLQQTANNCPDTKLVVGGYSLGAGVVDTALGV
MUL_0856|M.ulcerans_Agy99 PASRLQLHGGDGANDVISHVKSMASSCPNTKIVQGGYSQGADVIDIVAGV
*. . ****: ::: .**:*::* **** ** * * . ..
Mb2323|M.bovis_AF2122/97 P-----TQMWGFTNPLPPGSDEHIAAVALFGNGSQWVGPITNFS-PAYND
Rv2301|M.tuberculosis_H37Rv P-----TQMWGFTNPLPPGSDEHIAAVALFGNGSQWVGPITNFS-PAYND
MMAR_2908|M.marinum_M P-----MSAFGFENPLPPGTDQHIAAVALFGNGSQWVGPITNFS-PLYND
MAV_2759|M.avium_104 P-----IGAFGFDSPLPPGVDQHIAAVALFGNGSQWVGPITNFN-PTYND
MSMEG_1526|M.smegmatis_MC2_155 P-----FTAFGFKNPLPAGADQHIAAVALFGNGAAWVGPITNFS-PVYND
Mflv_4967|M.gilvum_PYR-GCK P-----IAAFGFKNPLPDGVDRHIAAVALFGNGSQWVGPIANFTNPALRD
Mvan_1439|M.vanbaalenii_PYR-1 P-----IAAFGFKSPLPDGVDRHIAAVALFGNGSQWVGPIANFTNPALRD
TH_3765|M.thermoresistible__bu P-----ISALGFDSPLPAGVDRHIAAIALFGNGIAWAGPISNFS-PLYAE
MAB_3763|M.abscessus_ATCC_1997 PGPVQIGNLFSFDNPVPPEVGDHIRAIVTFGNIVNRFAPVQSLA-GAYGD
MUL_0856|M.ulcerans_Agy99 P-----LAGISFGNELPAQYADNIAAVAVFGNVANRSGGSLTTQSSLLGS
* .* . :* :* *:. *** . . .
Mb2323|M.bovis_AF2122/97 RTIELCHGDDPVCHPADPNTWEANWPQHLAGAYVSSGMVNQAADFVAGKL
Rv2301|M.tuberculosis_H37Rv RTIELCHGDDPVCHPADPNTWEANWPQHLAGAYVSSGMVNQAADFVAGKL
MMAR_2908|M.marinum_M RTIELCHGADPICSPADPNTWKQNWPQHLASAYIQDGMVNEAADFVAGKL
MAV_2759|M.avium_104 RTIELCHGADPICNPADPNTWKQNWPQHLAGAYIDAGMADQAADFVAGKL
MSMEG_1526|M.smegmatis_MC2_155 RTIELCHGADPICNPADPNTWQNNWPDHLAGAYISGGMVNQAADFVASKL
Mflv_4967|M.gilvum_PYR-GCK RIVELCHGDDPICNPTAPENWQDNWPAHLASAYVGAGMVNQAADFIVGRL
Mvan_1439|M.vanbaalenii_PYR-1 RIIELCHGDDPICNPTAPENWQDYWPAHLAPAYIGAGMVNQAADFIVGRL
TH_3765|M.thermoresistible__bu RTIELCHGADPICNPADPETWRDNWSDHAATKYVQSGMVDQAADFVAARL
MAB_3763|M.abscessus_ATCC_1997 RVLDLCNDGDPVCMDGNQDTWKS----HTS---YPPALINQAADFAAARV
MUL_0856|M.ulcerans_Agy99 KSIDLCNPSDPICHSGPGNDWNGHTDGYVP-TYTTQAASFVAAKLAASSM
: ::**: **:* : *. : . . **.: .. :
Mb2323|M.bovis_AF2122/97 Q-----------------------------------------
Rv2301|M.tuberculosis_H37Rv Q-----------------------------------------
MMAR_2908|M.marinum_M ------------------------------------------
MAV_2759|M.avium_104 ------------------------------------------
MSMEG_1526|M.smegmatis_MC2_155 ------------------------------------------
Mflv_4967|M.gilvum_PYR-GCK ------------------------------------------
Mvan_1439|M.vanbaalenii_PYR-1 ------------------------------------------
TH_3765|M.thermoresistible__bu ------------------------------------------
MAB_3763|M.abscessus_ATCC_1997 N-----------------------------------------
MUL_0856|M.ulcerans_Agy99 APVVRLPGPVPRAPGPAPQAPGPATASPGTPVGATGTLVGAH