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FERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQ QAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQL LSGYQGKEAAEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNN PVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGD IILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPT VEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPDL REFDEKIAEARREKESAIDAQDFEKAASLRDREKTLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNW TGIPVFKLTEAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTE LSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAH QEIYNSLLQVLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSKGGGENDYERMKQKVNDEL KKHFRPEFLNRIDDIIVFHQLTREEIIRMVDLMISRVAGQLKSKDMALVLTDAAKALLAKRGFDPVLGAR PLRRTIQREIEDQLSEKILFEEVGPGQVVTVDVDNWDGEGPGEDAVFTFTGTRKPPAEPDLAKAGAHSAG GPEPAAR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv3596c | clpC1 | - | 100% (848) | PROBABLE ATP-DEPENDENT PROTEASE ATP-BINDING SUBUNIT CLPC1 |
M. tuberculosis H37Rv | Rv0384c | clpB | 0.0 | 47.46% (866) | endopeptidase ATP binding protein |
M. tuberculosis H37Rv | Rv2667 | clpC2 | 4e-20 | 38.61% (158) | ATP-dependent protease ATP-binding subunit ClpC2 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3627c | clpC | 0.0 | 100.00% (848) | ATP-dependent Clp protease ATP-binding subunit CLPC |
M. gilvum PYR-GCK | Mflv_1430 | - | 0.0 | 94.70% (849) | ATPase |
M. leprae Br4923 | MLBr_00235 | clpC | 0.0 | 97.16% (845) | putative ATP-dependent Clp protease |
M. abscessus ATCC 19977 | MAB_0546 | - | 0.0 | 92.56% (847) | ATP-dependent Clp protease ATP-binding subunit |
M. marinum M | MMAR_5100 | clpC1 | 0.0 | 98.11% (845) | ATP-dependent protease ATP-binding subunit ClpC1 |
M. avium 104 | MAV_0556 | - | 0.0 | 98.17% (819) | negative regulator of genetic competence ClpC/mecB |
M. smegmatis MC2 155 | MSMEG_6091 | - | 0.0 | 95.38% (845) | negative regulator of genetic competence ClpC/mecB |
M. thermoresistible (build 8) | TH_2346 | clpC | 0.0 | 93.97% (829) | PROBABLE ATP-DEPENDENT PROTEASE ATP-BINDING SUBUNIT CLPC1 |
M. ulcerans Agy99 | MUL_4178 | clpC1 | 0.0 | 97.75% (846) | ATP-dependent protease ATP-binding subunit ClpC1 |
M. vanbaalenii PYR-1 | Mvan_5358 | - | 0.0 | 94.81% (848) | ATPase |
CLUSTAL 2.0.9 multiple sequence alignment Rv3596c|M.tuberculosis_H37Rv MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE Mb3627c|M.bovis_AF2122/97 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE MLBr_00235|M.leprae_Br4923 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLD MMAR_5100|M.marinum_M MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE MUL_4178|M.ulcerans_Agy99 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE MAV_0556|M.avium_104 ---------------------MLNHNYIGTEHILLGLIHEGEGVAAKSLE Mflv_1430|M.gilvum_PYR-GCK MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE Mvan_5358|M.vanbaalenii_PYR-1 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE MAB_0546|M.abscessus_ATCC_1997 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE MSMEG_6091|M.smegmatis_MC2_155 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE TH_2346|M.thermoresistible__bu MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE ****************************: Rv3596c|M.tuberculosis_H37Rv SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH Mb3627c|M.bovis_AF2122/97 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH MLBr_00235|M.leprae_Br4923 SLGISLEAVRSQVEDIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH MMAR_5100|M.marinum_M SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH MUL_4178|M.ulcerans_Agy99 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH MAV_0556|M.avium_104 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH Mflv_1430|M.gilvum_PYR-GCK SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH Mvan_5358|M.vanbaalenii_PYR-1 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH MAB_0546|M.abscessus_ATCC_1997 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH MSMEG_6091|M.smegmatis_MC2_155 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH TH_2346|M.thermoresistible__bu SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH *******.******:*********************************** Rv3596c|M.tuberculosis_H37Rv NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA Mb3627c|M.bovis_AF2122/97 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA MLBr_00235|M.leprae_Br4923 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA MMAR_5100|M.marinum_M NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA MUL_4178|M.ulcerans_Agy99 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA MAV_0556|M.avium_104 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA Mflv_1430|M.gilvum_PYR-GCK NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGRET Mvan_5358|M.vanbaalenii_PYR-1 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKET MAB_0546|M.abscessus_ATCC_1997 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKET MSMEG_6091|M.smegmatis_MC2_155 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA TH_2346|M.thermoresistible__bu NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA ***********************************************:*: Rv3596c|M.tuberculosis_H37Rv AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV Mb3627c|M.bovis_AF2122/97 AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV MLBr_00235|M.leprae_Br4923 AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMESKLDPVIGREKEIERV MMAR_5100|M.marinum_M AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV MUL_4178|M.ulcerans_Agy99 AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV MAV_0556|M.avium_104 AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV Mflv_1430|M.gilvum_PYR-GCK AEAGTGGRGGEAGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV Mvan_5358|M.vanbaalenii_PYR-1 AEAGTGGRGGEAGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV MAB_0546|M.abscessus_ATCC_1997 AESGTGGRGGEAGTPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV MSMEG_6091|M.smegmatis_MC2_155 AEAGTGGRGGESGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV TH_2346|M.thermoresistible__bu AEAGTGGRGGESGNPSTSLVLDQFGRNLTQAAAEGKLDPVIGREKEVERI **:********:*.*************** ** *.***********:**: Rv3596c|M.tuberculosis_H37Rv MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL Mb3627c|M.bovis_AF2122/97 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL MLBr_00235|M.leprae_Br4923 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL MMAR_5100|M.marinum_M MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL MUL_4178|M.ulcerans_Agy99 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL MAV_0556|M.avium_104 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGQVPETLKDKQLYTL Mflv_1430|M.gilvum_PYR-GCK MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGDVPETLKDKQLYTL Mvan_5358|M.vanbaalenii_PYR-1 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL MAB_0546|M.abscessus_ATCC_1997 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKNKQLYTL MSMEG_6091|M.smegmatis_MC2_155 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL TH_2346|M.thermoresistible__bu MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVAGEVPETLKDKQLYTL ********************************** *:******:****** Rv3596c|M.tuberculosis_H37Rv DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG Mb3627c|M.bovis_AF2122/97 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG MLBr_00235|M.leprae_Br4923 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG MMAR_5100|M.marinum_M DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG MUL_4178|M.ulcerans_Agy99 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG MAV_0556|M.avium_104 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG Mflv_1430|M.gilvum_PYR-GCK DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG Mvan_5358|M.vanbaalenii_PYR-1 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG MAB_0546|M.abscessus_ATCC_1997 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG MSMEG_6091|M.smegmatis_MC2_155 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG TH_2346|M.thermoresistible__bu DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG ************************************************** Rv3596c|M.tuberculosis_H37Rv AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP Mb3627c|M.bovis_AF2122/97 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP MLBr_00235|M.leprae_Br4923 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP MMAR_5100|M.marinum_M AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP MUL_4178|M.ulcerans_Agy99 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP MAV_0556|M.avium_104 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP Mflv_1430|M.gilvum_PYR-GCK AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP Mvan_5358|M.vanbaalenii_PYR-1 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP MAB_0546|M.abscessus_ATCC_1997 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP MSMEG_6091|M.smegmatis_MC2_155 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP TH_2346|M.thermoresistible__bu AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP ************************************************** Rv3596c|M.tuberculosis_H37Rv TVEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAI Mb3627c|M.bovis_AF2122/97 TVEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAI MLBr_00235|M.leprae_Br4923 TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI MMAR_5100|M.marinum_M TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI MUL_4178|M.ulcerans_Agy99 TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI MAV_0556|M.avium_104 TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAI Mflv_1430|M.gilvum_PYR-GCK TVAHTIEILKGLRDRYEAHHRVSITDGAIAAAATLADRYINDRFLPDKAI Mvan_5358|M.vanbaalenii_PYR-1 TVEHTIEILKGLRDRYEAHHRVSITDSALVAAATLADRYINDRFLPDKAI MAB_0546|M.abscessus_ATCC_1997 TVEHTIEILKGLRDRYEAHHRVSITDGALVAAATLADRYINDRFLPDKAI MSMEG_6091|M.smegmatis_MC2_155 TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI TH_2346|M.thermoresistible__bu TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAI ** ***********************.*:.*************:****** Rv3596c|M.tuberculosis_H37Rv DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL Mb3627c|M.bovis_AF2122/97 DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL MLBr_00235|M.leprae_Br4923 DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL MMAR_5100|M.marinum_M DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL MUL_4178|M.ulcerans_Agy99 DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL MAV_0556|M.avium_104 DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL Mflv_1430|M.gilvum_PYR-GCK DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL Mvan_5358|M.vanbaalenii_PYR-1 DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL MAB_0546|M.abscessus_ATCC_1997 DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAARL MSMEG_6091|M.smegmatis_MC2_155 DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAAAL TH_2346|M.thermoresistible__bu DLIDEAGARMRIRRMTAPPDLREFDEKIAETRREKESAIDAQDFEKAAAL *****************************::***************** * Rv3596c|M.tuberculosis_H37Rv RDREKTLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT Mb3627c|M.bovis_AF2122/97 RDREKTLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT MLBr_00235|M.leprae_Br4923 RDREKQLVAQRAEREKQWRSGDLDVIAEVDDEQIAEVLGNWTGIPVFKLT MMAR_5100|M.marinum_M RDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT MUL_4178|M.ulcerans_Agy99 RDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT MAV_0556|M.avium_104 RDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT Mflv_1430|M.gilvum_PYR-GCK RDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT Mvan_5358|M.vanbaalenii_PYR-1 RDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT MAB_0546|M.abscessus_ATCC_1997 RDSEKQLVAQRADREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT MSMEG_6091|M.smegmatis_MC2_155 RDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT TH_2346|M.thermoresistible__bu RDQEKQLVAQRAEREKQWRAGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT ** ** ******:******:*****:************************ Rv3596c|M.tuberculosis_H37Rv EAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI Mb3627c|M.bovis_AF2122/97 EAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI MLBr_00235|M.leprae_Br4923 EAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI MMAR_5100|M.marinum_M EAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI MUL_4178|M.ulcerans_Agy99 EAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI MAV_0556|M.avium_104 EAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI Mflv_1430|M.gilvum_PYR-GCK EEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI Mvan_5358|M.vanbaalenii_PYR-1 EEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI MAB_0546|M.abscessus_ATCC_1997 EEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPRRPSGSFI MSMEG_6091|M.smegmatis_MC2_155 EEETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI TH_2346|M.thermoresistible__bu EAETTRLLRMEEELHKRIIGQEDAVRAVSKAIRRTRAGLKDPKRPSGSFI * *********:*************:****************:******* Rv3596c|M.tuberculosis_H37Rv FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG Mb3627c|M.bovis_AF2122/97 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG MLBr_00235|M.leprae_Br4923 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG MMAR_5100|M.marinum_M FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG MUL_4178|M.ulcerans_Agy99 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG MAV_0556|M.avium_104 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG Mflv_1430|M.gilvum_PYR-GCK FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG Mvan_5358|M.vanbaalenii_PYR-1 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG MAB_0546|M.abscessus_ATCC_1997 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG MSMEG_6091|M.smegmatis_MC2_155 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG TH_2346|M.thermoresistible__bu FAGPSGVGKTELSKALAEFLFGDEDALIQIDMGEYHDRFTASRLFGAPPG *****************:*****:**********:*************** Rv3596c|M.tuberculosis_H37Rv YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG Mb3627c|M.bovis_AF2122/97 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG MLBr_00235|M.leprae_Br4923 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG MMAR_5100|M.marinum_M YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG MUL_4178|M.ulcerans_Agy99 YVGYEEGGQLTEKVRRKPFSVALFDEIEKAHQEISNSLLQVLEDGRLTDG MAV_0556|M.avium_104 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG Mflv_1430|M.gilvum_PYR-GCK YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG Mvan_5358|M.vanbaalenii_PYR-1 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG MAB_0546|M.abscessus_ATCC_1997 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQVLEDGRLTDG MSMEG_6091|M.smegmatis_MC2_155 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG TH_2346|M.thermoresistible__bu YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQVLEDGRLTDG *********************.************ *:************* Rv3596c|M.tuberculosis_H37Rv QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSKGGGENDYERMKQKVNDE Mb3627c|M.bovis_AF2122/97 QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSKGGGENDYERMKQKVNDE MLBr_00235|M.leprae_Br4923 QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGSGENDYERMKQKVNDE MMAR_5100|M.marinum_M QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSQTGGENDYERMKQKVNDE MUL_4178|M.ulcerans_Agy99 QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSQTGGENDYERMKQKVNDE MAV_0556|M.avium_104 QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGGGENNYERMKQKVNDE Mflv_1430|M.gilvum_PYR-GCK QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVHDE Mvan_5358|M.vanbaalenii_PYR-1 QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVHDE MAB_0546|M.abscessus_ATCC_1997 QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSEGAAGSNYERMKQKVHDE MSMEG_6091|M.smegmatis_MC2_155 QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSQGGSENNYERMKQKVHDE TH_2346|M.thermoresistible__bu QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSQGGSENNYERMKQKVHDE *************************.*****:: .. .:********:** Rv3596c|M.tuberculosis_H37Rv LKKHFRPEFLNRIDDIIVFHQLTREEIIRMVDLMISRVAGQLKS-KDMAL Mb3627c|M.bovis_AF2122/97 LKKHFRPEFLNRIDDIIVFHQLTREEIIRMVDLMISRVAGQLKS-KDMAL MLBr_00235|M.leprae_Br4923 LKKHFRPEFLNRIDDIIVFHQLSRDEIIRMVDLMISRVANQLKV-KDMTL MMAR_5100|M.marinum_M LKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMIGRVANQLKS-KDMAL MUL_4178|M.ulcerans_Agy99 LKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMIGRVANQLKSSKDMAL MAV_0556|M.avium_104 LKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMITRVAGQLKS-KDMDL Mflv_1430|M.gilvum_PYR-GCK LKKHFRPEFLNRIDDIIVFHQLTQDEIIQMVDLMIGRVGNQLKA-KDMAM Mvan_5358|M.vanbaalenii_PYR-1 LKKHFRPEFLNRIDDIIVFHQLTQDEIIKMVDLMIGRVSKQLAA-KDMTM MAB_0546|M.abscessus_ATCC_1997 LKKHFRPEFLNRIDDIIVFEQLTQEQIIEMVDLMIGRVGKQLKT-KDMAM MSMEG_6091|M.smegmatis_MC2_155 LKKHFRPEFLNRIDDIIVFHQLTQDEIIQMVDLMIGRVSNQLKT-KDMAL TH_2346|M.thermoresistible__bu LKKHFRPEFLNRIDDIIVFHQLTQEQIIQMVDLMIDRVRNQLKA-KDMDL *******************.**::::**.****** ** ** *** : Rv3596c|M.tuberculosis_H37Rv VLTDAAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV Mb3627c|M.bovis_AF2122/97 VLTDAAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV MLBr_00235|M.leprae_Br4923 ELTNKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV MMAR_5100|M.marinum_M ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV MUL_4178|M.ulcerans_Agy99 ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV MAV_0556|M.avium_104 VLTDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQI Mflv_1430|M.gilvum_PYR-GCK ELTPKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEELGPGQL Mvan_5358|M.vanbaalenii_PYR-1 ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQL MAB_0546|M.abscessus_ATCC_1997 ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDALSEKILFNEVGPGEL MSMEG_6091|M.smegmatis_MC2_155 ELSDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEIGPGQL TH_2346|M.thermoresistible__bu QLTDKAKQLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEELRPGQL *: ** ************************** *******:*: **:: Rv3596c|M.tuberculosis_H37Rv VTVDVDNWDGEGPGEDAVF------------------------------- Mb3627c|M.bovis_AF2122/97 VTVDVDNWDGEGPGEDAVF------------------------------- MLBr_00235|M.leprae_Br4923 VTVDVDNWDGEGPGEDVKF------------------------------- MMAR_5100|M.marinum_M VTVDVDNWDGEGAGEDAKF------------------------------- MUL_4178|M.ulcerans_Agy99 VTVDVDNWDGEGAGEDAKF------------------------------- MAV_0556|M.avium_104 VTVDVDNWDGESAGEDAVF------------------------------- Mflv_1430|M.gilvum_PYR-GCK VTVDVENWDGEGQGEDAVF------------------------------- Mvan_5358|M.vanbaalenii_PYR-1 VTVDVEGWDGEGAGEDAKF------------------------------- MAB_0546|M.abscessus_ATCC_1997 VTVDVENWDGESAGEDAKF------------------------------- MSMEG_6091|M.smegmatis_MC2_155 VTVDVEGWDGEGQGEDAKF------------------------------- TH_2346|M.thermoresistible__bu ITVDVENWDGEGAGEDAXXXPTPPTGPAADVLNQATRVVPPAAPPSGTSA :****:.****. ***. Rv3596c|M.tuberculosis_H37Rv --------------------TFTGTRKPPAEPDLAKAGAHSAGGPEPAAR Mb3627c|M.bovis_AF2122/97 --------------------TFTGTRKPPAEPDLAKAGAHSAGGPEPAAR MLBr_00235|M.leprae_Br4923 --------------------TFTGIRKPSTEPDLAKAGVHSAGGPEPVEQ MMAR_5100|M.marinum_M --------------------TFTGTRKPPSEPDLAKAGAHSAGGPGPTEQ MUL_4178|M.ulcerans_Agy99 --------------------TFTGTRKPPSEPDLAKAGAHSAGGPGPTEQ MAV_0556|M.avium_104 --------------------TFTGTRKPPAEPDLAKAGAHSADPQ----- Mflv_1430|M.gilvum_PYR-GCK --------------------TFSGARKPVEVAEPDLAQAGAGGAGPAAE- Mvan_5358|M.vanbaalenii_PYR-1 --------------------TFIGTKKPVKIEEPDLAQAGAAGGPSAAE- MAB_0546|M.abscessus_ATCC_1997 --------------------TFVGRPKPALVAG---EEPAADLAASASE- MSMEG_6091|M.smegmatis_MC2_155 --------------------TFSGGPKRAETAEPDLAGAGAAGAPTAGTE TH_2346|M.thermoresistible__bu ARSGLLPSLLLPLQTTANTVTSVVPPPPPPAPGTPEAAVLETASGSASAA * Rv3596c|M.tuberculosis_H37Rv -------------------------------------------------- Mb3627c|M.bovis_AF2122/97 -------------------------------------------------- MLBr_00235|M.leprae_Br4923 -------------------------------------------------- MMAR_5100|M.marinum_M -------------------------------------------------- MUL_4178|M.ulcerans_Agy99 -------------------------------------------------- MAV_0556|M.avium_104 -------------------------------------------------- Mflv_1430|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5358|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0546|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_6091|M.smegmatis_MC2_155 -------------------------------------------------- TH_2346|M.thermoresistible__bu MPGVAAATSTLFSPPELNLPSIPGVGIPLPNRLSLPTDGICEGLGWSAGK Rv3596c|M.tuberculosis_H37Rv ----------------------- Mb3627c|M.bovis_AF2122/97 ----------------------- MLBr_00235|M.leprae_Br4923 ----------------------- MMAR_5100|M.marinum_M ----------------------- MUL_4178|M.ulcerans_Agy99 ----------------------- MAV_0556|M.avium_104 ----------------------- Mflv_1430|M.gilvum_PYR-GCK ----------------------- Mvan_5358|M.vanbaalenii_PYR-1 ----------------------- MAB_0546|M.abscessus_ATCC_1997 ----------------------- MSMEG_6091|M.smegmatis_MC2_155 ----------------------- TH_2346|M.thermoresistible__bu SDGQGAEVPAAPVPADRRDRWDR