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DSFNPTTKTQAALTAALQAASTAGNPEIRPAHLLMALLTQNDGIAAPLLEAVGVEPATVRAETQRLLDRL PQATGASTQPQLSRESLAAITTAQQLATELDDEYVSTEHVMVGLATGDSDVAKLLTGHGASPQALREAFV KVRGSARVTSPEPEATYQALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEPGVG KTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELH TIVGAGATGEGAMDAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSVEDTIGIL RGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDLVDEAASRLRMEIDSRPVEIDEVERLVR RLEIEEMALSKEEDEASAERLAKLRSELADQKEKLAELTTRWQNEKNAIEIVRDLKEQLEALRGESERAE RDGDLAKAAELRYGRIPEVEKKLDAALPQAQAREQVMLKEEVGPDDIADVVSAWTGIPAGRLLEGETAKL LRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVSDPNRPTGAFMFLGPTGVGKTELAKALADFLFDDERAM VRIDMSEYGEKHTVARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQVLDEGRL TDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRATFKPEFINRLDDVLIFEGLNPEELVRIVDIQLAQ LGKRLAQRRLQLQVSLPAKRWLAQRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPD ADSLILG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0384c | clpB | - | 100% (848) | PROBABLE ENDOPEPTIDASE ATP BINDING PROTEIN (CHAIN B) CLPB (CLPB PROTEIN) (HEAT SHOCK PROTEIN F84.1) |
M. tuberculosis H37Rv | Rv3596c | clpC1 | 0.0 | 47.46% (866) | ATP-dependent protease ATP-binding subunit ClpC1 |
M. tuberculosis H37Rv | Rv2667 | clpC2 | 2e-06 | 30.91% (110) | ATP-dependent protease ATP-binding subunit ClpC2 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0391c | clpB | 0.0 | 100.00% (848) | endopeptidase ATP-binding protein ClpB |
M. gilvum PYR-GCK | Mflv_0246 | - | 0.0 | 88.80% (848) | ATPase |
M. leprae Br4923 | MLBr_02490 | clpB | 0.0 | 89.15% (848) | heat shock protein |
M. abscessus ATCC 19977 | MAB_4265c | - | 0.0 | 86.32% (848) | chaperone ClpB |
M. marinum M | MMAR_0645 | clpB | 0.0 | 93.04% (848) | endopeptidase ATP binding protein (chain B) ClpB |
M. avium 104 | MAV_4793 | - | 0.0 | 92.69% (848) | chaperone ClpB |
M. smegmatis MC2 155 | MSMEG_0732 | - | 0.0 | 90.45% (848) | chaperone ClpB |
M. thermoresistible (build 8) | TH_2647 | - | 0.0 | 87.50% (848) | PUTATIVE chaperone ClpB |
M. ulcerans Agy99 | MUL_0127 | clpB | 0.0 | 92.92% (848) | endopeptidase ATP binding protein (chain B) ClpB |
M. vanbaalenii PYR-1 | Mvan_0659 | - | 0.0 | 89.27% (848) | ATPase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0246|M.gilvum_PYR-GCK ------MDSFNPTTKTQAALTSALQAATAAGNPQITPAHLLMALLTQNDG Mvan_0659|M.vanbaalenii_PYR-1 ------MDSFNPTTKTQAALTSALQAATAAGNPQIAPAHLLMALLTQNDG MSMEG_0732|M.smegmatis_MC2_155 ------MDSFNPTTKTQAALTSALQAASSAGNPEIRPAHLLMALLTQNDG TH_2647|M.thermoresistible__bu LTIGGVVDSFNPTTKTQAALTAALQAATAAGHPQIQPAHLLMALLTQHDG Rv0384c|M.tuberculosis_H37Rv ------MDSFNPTTKTQAALTAALQAASTAGNPEIRPAHLLMALLTQNDG Mb0391c|M.bovis_AF2122/97 ------MDSFNPTTKTQAALTAALQAASTAGNPEIRPAHLLMALLTQNDG MMAR_0645|M.marinum_M ------MDSFNPTTKTQAALTSALQAASAAGNPEIRPAHLLMALLTQADG MUL_0127|M.ulcerans_Agy99 ------MDSFNPTTKTQAALTSALQAASAAGNPEIRPAHLLMALLTQADG MLBr_02490|M.leprae_Br4923 ------MDSFNPTTKMQVALTSALQAASSAGNPEIRPVHLLLAMLMQNDG MAV_4793|M.avium_104 ------MDSFNPTTKTQAALTAALQAASAAGNPEIRPAHLLMALLTQADG MAB_4265c|M.abscessus_ATCC_199 ------MDSFNPTTKTQAALTAALQAATTAGNPEIRPAHLLVALLGQTDG :******** *.***:*****::**:*:* *.***:*:* * ** Mflv_0246|M.gilvum_PYR-GCK IAAPLLEAVGVEPATIRAETQRLLDRLPSATGSASQPQLSPPAIAAITAA Mvan_0659|M.vanbaalenii_PYR-1 IAAPLLEAVGVEPATIRAETQRLLDRLPSATGSSSQPQLAPQAIAAITAA MSMEG_0732|M.smegmatis_MC2_155 IAAPLLEAVGVEPATIRTETQRLLDRLPSASGASSQPQLSRESLAAITTA TH_2647|M.thermoresistible__bu IAAPLLEAVGVEPATIRAEVQRVLDQQPKISGGASQPQLSRDSLNAITTA Rv0384c|M.tuberculosis_H37Rv IAAPLLEAVGVEPATVRAETQRLLDRLPQATGASTQPQLSRESLAAITTA Mb0391c|M.bovis_AF2122/97 IAAPLLEAVGVEPATVRAETQRLLDRLPQATGASTQPQLSRESLAAITTA MMAR_0645|M.marinum_M IAAPLLEAVGVDPATIRTEAQRLVDRLPQASGASTQPQLSRESLAAITTA MUL_0127|M.ulcerans_Agy99 IAAPLLEAVGVDPATIRTEAQRLVDRLPQASGASTQPQLSRESLAAITTA MLBr_02490|M.leprae_Br4923 IAAPLLETVGVEPDIVRNEAQRLLERLPQASGCSSQPQLSRESLAAITTA MAV_4793|M.avium_104 IAAPLLEAVGVEPATIRAEAERMLARLPQASGASSQPQLSRESLAAITTA MAB_4265c|M.abscessus_ATCC_199 IAAPLLQAVGVDPVSVRNEAQAIADRLPQVSNASANPQLSRDSIAAVTAA ******::***:* :* *.: : : *. :. :::***: :: *:*:* Mflv_0246|M.gilvum_PYR-GCK THLATEMDDEYVSTEHLLVGLATGDSDVAKVLTGHGASPQALREAFVKVR Mvan_0659|M.vanbaalenii_PYR-1 THLASEMDDEYVSTEHLLVGLATGDADTAKLLTGHGASPQALREAFVKVR MSMEG_0732|M.smegmatis_MC2_155 QNLATEMDDEYVSTEHLMVGLATGDSEVAKLLTGHGASPQALREAFVKVR TH_2647|M.thermoresistible__bu QQLATEMADEYVSTEHLLVGLASGDSDVAKILNGHGATPQALREAFAKVR Rv0384c|M.tuberculosis_H37Rv QQLATELDDEYVSTEHVMVGLATGDSDVAKLLTGHGASPQALREAFVKVR Mb0391c|M.bovis_AF2122/97 QQLATELDDEYVSTEHVMVGLATGDSDVAKLLTGHGASPQALREAFVKVR MMAR_0645|M.marinum_M QQLATEMDDEYVSTEHVLVGLATGDSEVAKLLTGHGASPQALREAFVKVR MUL_0127|M.ulcerans_Agy99 QQLATEMDDEYVSTEHVLVGLATGDSEVAKLLTGHGASPQALREAFVKVR MLBr_02490|M.leprae_Br4923 QQLATEMDDEYVSTEHLMLGLAMGDSDVAKLLTGHGASPQVLREAFVKIR MAV_4793|M.avium_104 QHLATELDDEYVSTEHLMVGLATGDSDVAKLLTGHGASPQALREAFVKVR MAB_4265c|M.abscessus_ATCC_199 QHLATELNDDYVSTEHLLVGLATGDSDIAKLLVNHGATPQALRDAFVQVR :**:*: *:******:::*** **:: **:* .***:**.**:**.::* Mflv_0246|M.gilvum_PYR-GCK GSARVTNPDPEGTYQALEKYSTDLTARAREGKLDPVIGRDHEIRRVVQVL Mvan_0659|M.vanbaalenii_PYR-1 GSARVTSPDPEGTYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL MSMEG_0732|M.smegmatis_MC2_155 GSARVTSPDPEGTYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL TH_2647|M.thermoresistible__bu GSARVTTPDPEGTYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVIQVL Rv0384c|M.tuberculosis_H37Rv GSARVTSPEPEATYQALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL Mb0391c|M.bovis_AF2122/97 GSARVTSPEPEATYQALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL MMAR_0645|M.marinum_M GSARVTSPEPEATYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL MUL_0127|M.ulcerans_Agy99 GSARVTSPEPEATYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL MLBr_02490|M.leprae_Br4923 GSARVTSSDPEFTYQALEKYSTDLTAQSGEGKLDPVIGRDNEIRRVVQVL MAV_4793|M.avium_104 GSARVTSPDPEATYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL MAB_4265c|M.abscessus_ATCC_199 GSGRVTSPEPEATFQALEKYSTDLTARAREGKLDPVIGRDTEIRRVVQVL **.***..:** *:***:********:: *********** *****:*** Mflv_0246|M.gilvum_PYR-GCK SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVVSLDMGS Mvan_0659|M.vanbaalenii_PYR-1 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIIAGDVPESLRDKTVVSLDLGS MSMEG_0732|M.smegmatis_MC2_155 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVIALDLGS TH_2647|M.thermoresistible__bu SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVIALDLGS Rv0384c|M.tuberculosis_H37Rv SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGS Mb0391c|M.bovis_AF2122/97 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGS MMAR_0645|M.marinum_M SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGS MUL_0127|M.ulcerans_Agy99 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGS MLBr_02490|M.leprae_Br4923 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTLVALDLGS MAV_4793|M.avium_104 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVIALDLGS MAB_4265c|M.abscessus_ATCC_199 SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRGKTVISLDLGS *****************************:*********.**:::**:** Mflv_0246|M.gilvum_PYR-GCK MVAGAKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGESAM Mvan_0659|M.vanbaalenii_PYR-1 MVAGAKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGESAM MSMEG_0732|M.smegmatis_MC2_155 MVAGAKYRGEFEERLKAVLDDIKNSAGQVITFIDELHTIVGAGATGESAM TH_2647|M.thermoresistible__bu MVAGSKYRGEFEERLKAVLDEIKNSAGQIITFIDELHTIVGAGATGDGSM Rv0384c|M.tuberculosis_H37Rv MVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM Mb0391c|M.bovis_AF2122/97 MVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM MMAR_0645|M.marinum_M MVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM MUL_0127|M.ulcerans_Agy99 MVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM MLBr_02490|M.leprae_Br4923 MVAGAKYRGEFEQRLKVVLDDIKFSAGQIITFIDELHTIVGAGATGESAM MAV_4793|M.avium_104 MVAGAKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM MAB_4265c|M.abscessus_ATCC_199 MVAGAKYRGEFEERLKAVLDEIKNSAGQLITFIDELHTIVGAGATGESAM ****:*******:***.***:** ****:*****************:.:* Mflv_0246|M.gilvum_PYR-GCK DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVLVGEPSV Mvan_0659|M.vanbaalenii_PYR-1 DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVMVGEPSV MSMEG_0732|M.smegmatis_MC2_155 DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVFVGEPSV TH_2647|M.thermoresistible__bu DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVYVGEPSV Rv0384c|M.tuberculosis_H37Rv DAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSV Mb0391c|M.bovis_AF2122/97 DAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSV MMAR_0645|M.marinum_M DAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSA MUL_0127|M.ulcerans_Agy99 DAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSA MLBr_02490|M.leprae_Br4923 DAGNMIKPMLARGELRLVGATTLDEYRRYIEKDAALERRFQQIFVGEPSV MAV_4793|M.avium_104 DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVFVGEPSV MAB_4265c|M.abscessus_ATCC_199 DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVLVGEPSV ***************************::*************: *****. Mflv_0246|M.gilvum_PYR-GCK EDTVGILRGLKDRYEVHHGVRITDSSLVAAATLSDRYITSRFLPDKAIDL Mvan_0659|M.vanbaalenii_PYR-1 EDTVGILRGLKERYEVHHGVRITDSALVSAATLSDRYITARFLPDKAIDL MSMEG_0732|M.smegmatis_MC2_155 EDTVGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL TH_2647|M.thermoresistible__bu EDTIGILRGLKERYEVHHGVRITDSALVAAATLSNRYITARFLPDKAIDL Rv0384c|M.tuberculosis_H37Rv EDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL Mb0391c|M.bovis_AF2122/97 EDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL MMAR_0645|M.marinum_M EDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL MUL_0127|M.ulcerans_Agy99 EDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL MLBr_02490|M.leprae_Br4923 EDTVGILRGLKDRYEVHHGVRITDSALVAAAALSDRYITARFLPDKAIDL MAV_4793|M.avium_104 EDTVGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL MAB_4265c|M.abscessus_ATCC_199 EDTIGILRGIKERYEIHHGVRITDSALVAAATLSDRYITSRFLPDKAIDL ***:*****:*:***:*********:**:**:**:****:********** Mflv_0246|M.gilvum_PYR-GCK VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALAKEEDAASKDRLEK Mvan_0659|M.vanbaalenii_PYR-1 VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALEKESDAASKDRLEK MSMEG_0732|M.smegmatis_MC2_155 VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALEKEEDEASKDRLEK TH_2647|M.thermoresistible__bu VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASKERLEK Rv0384c|M.tuberculosis_H37Rv VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASAERLAK Mb0391c|M.bovis_AF2122/97 VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASAERLAK MMAR_0645|M.marinum_M VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDDASKDRLEK MUL_0127|M.ulcerans_Agy99 VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDDASKDRLEK MLBr_02490|M.leprae_Br4923 VDEAASRLRMEIDSRPVEIDEVERLVRRFEIEEMALVNEEDEASKERLET MAV_4793|M.avium_104 VDEAASRLKMEIDSRPVEIDEVERLVRRLEIEEMALAKEEDEASKERLEK MAB_4265c|M.abscessus_ATCC_199 VDEAASRLRMEIDSRPVEIDEVERVVRRLEIEEMALSKEEDEASKQRLEK ********:***************:***:******* :*.* ** :** . Mflv_0246|M.gilvum_PYR-GCK LRAELADKKEQLAELTTRWQNEKSAIDVVRELKEQLESLRGEADRAERDG Mvan_0659|M.vanbaalenii_PYR-1 LRSELADQKEKLSELTTRWQNEKGAIDVVRELKEQLEELRGAADRAERDG MSMEG_0732|M.smegmatis_MC2_155 LRAELADHKEKLSELTTRWQNEKNAINVVRELKEQLDTLRGEADRAERDG TH_2647|M.thermoresistible__bu LRAELADHKEKLAELTARWQNEKKAIETVRELKEQLEALKIEAERAERDG Rv0384c|M.tuberculosis_H37Rv LRSELADQKEKLAELTTRWQNEKNAIEIVRDLKEQLEALRGESERAERDG Mb0391c|M.bovis_AF2122/97 LRSELADQKEKLAELTTRWQNEKNAIEIVRDLKEQLEALRGESERAERDG MMAR_0645|M.marinum_M LRAELADKKEELAELTTRWQNEKNSIEIVRELKEQLDALRGESERAERDG MUL_0127|M.ulcerans_Agy99 LRAELADKKEELAELTTRWQNEKNSIEIVRELKEQLDALRGESERAERDG MLBr_02490|M.leprae_Br4923 LRAELADQKERLAELTARWQNEKNAIDVVRELKEQLETLRGESERAERDG MAV_4793|M.avium_104 LRSELADQKEKLAELTTRWQNEKNAIDVVRELKEQLETLRGESDRAERDG MAB_4265c|M.abscessus_ATCC_199 LRVELADKKERLAELTARWQNEKSSIDAVRDLKEQLETLKGESDRAERDG ** ****:**.*:***:****** :*: **:*****: *: ::****** Mflv_0246|M.gilvum_PYR-GCK DLAKAAELRYGRIPEVEKKLDAALPHAEARENVMLKEEVGPDDIAEVVEA Mvan_0659|M.vanbaalenii_PYR-1 DLAKAAELRYGRIPEVEKKLDAAVPQAEARDNVMLKEEVGPDDIADVVSA MSMEG_0732|M.smegmatis_MC2_155 DLAKAAELRYGRIPEVEKKLDAALPAAEARENLMLKEEVGPDDIAEVVEA TH_2647|M.thermoresistible__bu NYERVAELRYGRIPEVEKKLEAATPHAEARENVMLKEEVGPDDIAEVVSA Rv0384c|M.tuberculosis_H37Rv DLAKAAELRYGRIPEVEKKLDAALPQAQAREQVMLKEEVGPDDIADVVSA Mb0391c|M.bovis_AF2122/97 DLAKAAELRYGRIPEVEKKLDAALPQAQAREQVMLKEEVGPDDIADVVSA MMAR_0645|M.marinum_M DLAKAAELRYGRIPEMEKKLDAAVPHAQAREQVMLKEEVGPDDIAEVVSA MUL_0127|M.ulcerans_Agy99 DLAKAAELRYGRIPEMEKKLDAAVPHAQAREQVMLKEEVGPDDIAEVVSA MLBr_02490|M.leprae_Br4923 DLAKAAELRYGRIPEVEKKLEAAVPTAQAREDVMLKEEVGPDDIANVVSA MAV_4793|M.avium_104 DLAKAAELRYGRIPEVEKKLEAALPQAEARENVMLKEEVGPDDIAEVVSA MAB_4265c|M.abscessus_ATCC_199 DLGKAAELRYGRIPELEKQLEQALPGLDHDGNVMLKEEVSPDDVADVVSA : :.**********:**:*: * * : ::******.***:*:**.* Mflv_0246|M.gilvum_PYR-GCK WTGIPAGRMLEGETAKLLRMEEELGKRVVGQRKAVTAVSDAVRRSRAGVA Mvan_0659|M.vanbaalenii_PYR-1 WTGIPAGRMLEGETAKLLRMEDELGKRVVGQKNAVQAVSDAVRRSRAGVA MSMEG_0732|M.smegmatis_MC2_155 WTGIPSGRMLEGETAKLLRMEEELGKRVVGQRKAVQAVSDAVRRSRAGVA TH_2647|M.thermoresistible__bu WTGIPAGRMLEGEQAKLLRMEDELAKRVVGQKRAVQAVSDAVRRSRAGVA Rv0384c|M.tuberculosis_H37Rv WTGIPAGRLLEGETAKLLRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVS Mb0391c|M.bovis_AF2122/97 WTGIPAGRLLEGETAKLLRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVS MMAR_0645|M.marinum_M WTGIPAGRMLEGETAKLLRMEDELGHRVIGQKKAVQAVSDAVRRSRAGVA MUL_0127|M.ulcerans_Agy99 WTGIPAGRMLEGETAKLLRMEDELGHRVIGQKKAVQAVSDAVRRSRAGVA MLBr_02490|M.leprae_Br4923 WTGIPAGRLLEGETAKLLRMEDELGKRVVGQKKAVHAVSDAVRRSRAGVA MAV_4793|M.avium_104 WTGIPAGRMLEGETAKLLRMEDELGKRVVGQKRAVQAVSDAVRRARAGVA MAB_4265c|M.abscessus_ATCC_199 WTGIPTGRLMEGETAKLLRMEDELGKRVVGQKKAVEAVSDAVRRARAGVA *****:**::*** *******:**.:**:**: ** ********:****: Mflv_0246|M.gilvum_PYR-GCK DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS Mvan_0659|M.vanbaalenii_PYR-1 DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS MSMEG_0732|M.smegmatis_MC2_155 DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS TH_2647|M.thermoresistible__bu DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYSEKHS Rv0384c|M.tuberculosis_H37Rv DPNRPTGAFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYGEKHT Mb0391c|M.bovis_AF2122/97 DPNRPTGAFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYGEKHT MMAR_0645|M.marinum_M DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS MUL_0127|M.ulcerans_Agy99 DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS MLBr_02490|M.leprae_Br4923 DPNRPTGSFLFLGPTGVGKTELAKALADFLFDDQRAMVRVDMSEYGEKHS MAV_4793|M.avium_104 DPNRPTGSFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYGEKHS MAB_4265c|M.abscessus_ATCC_199 DPNRPTGSFLFLGPTGVGKTELAKALADFLFDDEHAMVRIDMSEYGEKHS *******:*:*****************:*****::****:*****.***: Mflv_0246|M.gilvum_PYR-GCK VARLVGAPPGYVGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ Mvan_0659|M.vanbaalenii_PYR-1 VARLVGAPPGYVGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ MSMEG_0732|M.smegmatis_MC2_155 VARLVGAPPGYIGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ TH_2647|M.thermoresistible__bu VARLVGAPPGYVGYDQGGQLTEAVRRRPYTVILFDEIEKAHQDVFDILLQ Rv0384c|M.tuberculosis_H37Rv VARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQ Mb0391c|M.bovis_AF2122/97 VARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQ MMAR_0645|M.marinum_M VARLVGAPPGYIGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ MUL_0127|M.ulcerans_Agy99 VARLVGAPPGYIGYDHGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ MLBr_02490|M.leprae_Br4923 VARLVGAPPGYIGHDQGGQLTEAVRRRPYTVVLFDEVEKAHSDVFDVLLQ MAV_4793|M.avium_104 VARLVGAPPGYIGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ MAB_4265c|M.abscessus_ATCC_199 VARLVGAPPGYVGYDAGGQLTEAVRRRPYTVVLFDEVEKAHPDVFDVLLQ ****:******:*:: ***************:****:**** ****:*** Mflv_0246|M.gilvum_PYR-GCK VLDEGRLTDGQGRTVDFRNTILILTSNLGAGGSEEQVMAAVRAAFKPEFI Mvan_0659|M.vanbaalenii_PYR-1 VLDEGRLTDGQGRTVDFRNTILILTSNLGAGGNEEQVMAAVRAAFKPEFI MSMEG_0732|M.smegmatis_MC2_155 VLDEGRLTDGQGRTVDFRNTILILTSNLGAGGNEDQVMAAVRSAFKPEFI TH_2647|M.thermoresistible__bu VLDDGRLTDGQGRTVDFRNTILILTSNLGAGGSEEQVMAAVRAHFKPEFI Rv0384c|M.tuberculosis_H37Rv VLDEGRLTDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRATFKPEFI Mb0391c|M.bovis_AF2122/97 VLDEGRLTDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRATFKPEFI MMAR_0645|M.marinum_M VLDEGRLTDGQGRTVDFRNTILILTSNLGSGGTPDQVMAAVRAAFKPEFI MUL_0127|M.ulcerans_Agy99 VLDEGRLTDGQGRTVDFRNTILILTSNLGSGGTPDQVMAAVRAAFKPEFI MLBr_02490|M.leprae_Br4923 VLDEGRLTDGQGRTVDFRNTIPILTSNLGSGGSEEQVMAAVRSVFKPEFI MAV_4793|M.avium_104 VLDEGRLTDGQGRTVDFRNTILILTSNLGSGGSEEQVMAAVRSAFKPEFI MAB_4265c|M.abscessus_ATCC_199 VLDEGRLTDGQGRTVDFRNTILILTSNLGAGGSEEQVMAAVRAKFKPEFI ***:******:********** *******:**. :**:****: ****** Mflv_0246|M.gilvum_PYR-GCK NRLDDVIMFDALDPEQLVSIVDIQLEQLAKRLAQRRLTLEVSLPAKKWLA Mvan_0659|M.vanbaalenii_PYR-1 NRLDDVIMFDALNPEQLVSIVDIQLAQLQKRLAQRRLTLEVSLPAKKWLA MSMEG_0732|M.smegmatis_MC2_155 NRLDDVIIFDGLNPEELVQIVDIQLAQLAKRLEQRRLTLEVSLPAKKWLG TH_2647|M.thermoresistible__bu NRLDDIIIFDGLNPEELVSIVDIQLAQLAKRLEQRRLTLQVSEPAKQWLA Rv0384c|M.tuberculosis_H37Rv NRLDDVLIFEGLNPEELVRIVDIQLAQLGKRLAQRRLQLQVSLPAKRWLA Mb0391c|M.bovis_AF2122/97 NRLDDVLIFEGLNPEELVRIVDIQLAQLGKRLAQRRLQLQVSLPAKRWLA MMAR_0645|M.marinum_M NRLDDVLIFDALNPDELVQIVDIQLQQLDKRLAQRRLQLEVSLPAKEWLA MUL_0127|M.ulcerans_Agy99 NRLDDVLIFDALNPDELVQIVDIQLQQLDKRLAQRRLQLEVSLPAKEWLA MLBr_02490|M.leprae_Br4923 NRLDDVLIFDGLNPEELVRIVDIQLEQLGKRLAQRRLQLEVSLPAKRWLA MAV_4793|M.avium_104 NRLDDVIIFHGLEPGELVQIVDIQLAQLQKRLAQRRLTLEVSLPAKQWLA MAB_4265c|M.abscessus_ATCC_199 NRLDDVLIFDGLNPEELVQIVDIQLGQLQKRLAQRRLTLEVSAPAKKWLA *****:::*..*:* :** ****** ** *** **** *:** ***.**. Mflv_0246|M.gilvum_PYR-GCK ERGFDPLYGARPLRRLVQQAIGDQLARMLLSGQVHDGDVVPVNLSADGDS Mvan_0659|M.vanbaalenii_PYR-1 ERGFDPLYGARPLRRLIQQAIGDQLAKLLLAGDVHDGDVVPVNVSPDGDS MSMEG_0732|M.smegmatis_MC2_155 QRGFDPLYGARPLRRLVQQAIGDQLAKMLLAGEVHDGDIVPVNVSPDGES TH_2647|M.thermoresistible__bu QRGFDPQYGARPLRRLIQKVIGDQLAKLLLAGEVHDGDVVPVNVAPDGNS Rv0384c|M.tuberculosis_H37Rv QRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPDADS Mb0391c|M.bovis_AF2122/97 QRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPDADS MMAR_0645|M.marinum_M QRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSADGES MUL_0127|M.ulcerans_Agy99 QRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSADGES MLBr_02490|M.leprae_Br4923 QHGFDPVYGARPLRRLVQQAIGDQLAKMLLAGEVHDGDTLPVNVRPDGEA MAV_4793|M.avium_104 HRGFDPVYGARPLRRLVQQAIGDQLAKQLLAGQVHDGDTVPVNVSPDGDS MAB_4265c|M.abscessus_ATCC_199 ARGFDPIYGARPLRRLVQQSIGDQLAKQLLAGEVHDGDVVPVNVSADGES :**** *********:*: ******: **:*:***** :***: .*.:: Mflv_0246|M.gilvum_PYR-GCK LVLG Mvan_0659|M.vanbaalenii_PYR-1 LVLG MSMEG_0732|M.smegmatis_MC2_155 LVLG TH_2647|M.thermoresistible__bu LVLG Rv0384c|M.tuberculosis_H37Rv LILG Mb0391c|M.bovis_AF2122/97 LILG MMAR_0645|M.marinum_M LVLG MUL_0127|M.ulcerans_Agy99 LVFG MLBr_02490|M.leprae_Br4923 LILG MAV_4793|M.avium_104 LILG MAB_4265c|M.abscessus_ATCC_199 LILG *::*