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M. tuberculosis H37Rv Rv0384c (clpB)

annotation: PROBABLE ENDOPEPTIDASE ATP BINDING PROTEIN (CHAIN B) CLPB (CLPB PROTEIN) (HEAT SHOCK PROTEIN F84.1)
coordinates: 459456 - 462002
length: 848

DSFNPTTKTQAALTAALQAASTAGNPEIRPAHLLMALLTQNDGIAAPLLEAVGVEPATVRAETQRLLDRL
PQATGASTQPQLSRESLAAITTAQQLATELDDEYVSTEHVMVGLATGDSDVAKLLTGHGASPQALREAFV
KVRGSARVTSPEPEATYQALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEPGVG
KTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELH
TIVGAGATGEGAMDAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSVEDTIGIL
RGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDLVDEAASRLRMEIDSRPVEIDEVERLVR
RLEIEEMALSKEEDEASAERLAKLRSELADQKEKLAELTTRWQNEKNAIEIVRDLKEQLEALRGESERAE
RDGDLAKAAELRYGRIPEVEKKLDAALPQAQAREQVMLKEEVGPDDIADVVSAWTGIPAGRLLEGETAKL
LRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVSDPNRPTGAFMFLGPTGVGKTELAKALADFLFDDERAM
VRIDMSEYGEKHTVARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQVLDEGRL
TDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRATFKPEFINRLDDVLIFEGLNPEELVRIVDIQLAQ
LGKRLAQRRLQLQVSLPAKRWLAQRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPD
ADSLILG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0384cclpB-100% (848)PROBABLE ENDOPEPTIDASE ATP BINDING PROTEIN (CHAIN B) CLPB (CLPB PROTEIN) (HEAT SHOCK PROTEIN F84.1)
M. tuberculosis H37RvRv3596cclpC10.047.46% (866) ATP-dependent protease ATP-binding subunit ClpC1
M. tuberculosis H37RvRv2667clpC22e-0630.91% (110) ATP-dependent protease ATP-binding subunit ClpC2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0391cclpB0.0100.00% (848) endopeptidase ATP-binding protein ClpB
M. gilvum PYR-GCKMflv_0246-0.088.80% (848) ATPase
M. leprae Br4923MLBr_02490clpB0.089.15% (848) heat shock protein
M. abscessus ATCC 19977MAB_4265c-0.086.32% (848) chaperone ClpB
M. marinum MMMAR_0645clpB0.093.04% (848) endopeptidase ATP binding protein (chain B) ClpB
M. avium 104MAV_4793-0.092.69% (848) chaperone ClpB
M. smegmatis MC2 155MSMEG_0732-0.090.45% (848) chaperone ClpB
M. thermoresistible (build 8)TH_2647-0.087.50% (848) PUTATIVE chaperone ClpB
M. ulcerans Agy99MUL_0127clpB0.092.92% (848) endopeptidase ATP binding protein (chain B) ClpB
M. vanbaalenii PYR-1Mvan_0659-0.089.27% (848) ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0246|M.gilvum_PYR-GCK          ------MDSFNPTTKTQAALTSALQAATAAGNPQITPAHLLMALLTQNDG
Mvan_0659|M.vanbaalenii_PYR-1       ------MDSFNPTTKTQAALTSALQAATAAGNPQIAPAHLLMALLTQNDG
MSMEG_0732|M.smegmatis_MC2_155      ------MDSFNPTTKTQAALTSALQAASSAGNPEIRPAHLLMALLTQNDG
TH_2647|M.thermoresistible__bu      LTIGGVVDSFNPTTKTQAALTAALQAATAAGHPQIQPAHLLMALLTQHDG
Rv0384c|M.tuberculosis_H37Rv        ------MDSFNPTTKTQAALTAALQAASTAGNPEIRPAHLLMALLTQNDG
Mb0391c|M.bovis_AF2122/97           ------MDSFNPTTKTQAALTAALQAASTAGNPEIRPAHLLMALLTQNDG
MMAR_0645|M.marinum_M               ------MDSFNPTTKTQAALTSALQAASAAGNPEIRPAHLLMALLTQADG
MUL_0127|M.ulcerans_Agy99           ------MDSFNPTTKTQAALTSALQAASAAGNPEIRPAHLLMALLTQADG
MLBr_02490|M.leprae_Br4923          ------MDSFNPTTKMQVALTSALQAASSAGNPEIRPVHLLLAMLMQNDG
MAV_4793|M.avium_104                ------MDSFNPTTKTQAALTAALQAASAAGNPEIRPAHLLMALLTQADG
MAB_4265c|M.abscessus_ATCC_199      ------MDSFNPTTKTQAALTAALQAATTAGNPEIRPAHLLVALLGQTDG
                                          :******** *.***:*****::**:*:* *.***:*:* * **

Mflv_0246|M.gilvum_PYR-GCK          IAAPLLEAVGVEPATIRAETQRLLDRLPSATGSASQPQLSPPAIAAITAA
Mvan_0659|M.vanbaalenii_PYR-1       IAAPLLEAVGVEPATIRAETQRLLDRLPSATGSSSQPQLAPQAIAAITAA
MSMEG_0732|M.smegmatis_MC2_155      IAAPLLEAVGVEPATIRTETQRLLDRLPSASGASSQPQLSRESLAAITTA
TH_2647|M.thermoresistible__bu      IAAPLLEAVGVEPATIRAEVQRVLDQQPKISGGASQPQLSRDSLNAITTA
Rv0384c|M.tuberculosis_H37Rv        IAAPLLEAVGVEPATVRAETQRLLDRLPQATGASTQPQLSRESLAAITTA
Mb0391c|M.bovis_AF2122/97           IAAPLLEAVGVEPATVRAETQRLLDRLPQATGASTQPQLSRESLAAITTA
MMAR_0645|M.marinum_M               IAAPLLEAVGVDPATIRTEAQRLVDRLPQASGASTQPQLSRESLAAITTA
MUL_0127|M.ulcerans_Agy99           IAAPLLEAVGVDPATIRTEAQRLVDRLPQASGASTQPQLSRESLAAITTA
MLBr_02490|M.leprae_Br4923          IAAPLLETVGVEPDIVRNEAQRLLERLPQASGCSSQPQLSRESLAAITTA
MAV_4793|M.avium_104                IAAPLLEAVGVEPATIRAEAERMLARLPQASGASSQPQLSRESLAAITTA
MAB_4265c|M.abscessus_ATCC_199      IAAPLLQAVGVDPVSVRNEAQAIADRLPQVSNASANPQLSRDSIAAVTAA
                                    ******::***:*  :* *.: :  : *. :. :::***:  :: *:*:*

Mflv_0246|M.gilvum_PYR-GCK          THLATEMDDEYVSTEHLLVGLATGDSDVAKVLTGHGASPQALREAFVKVR
Mvan_0659|M.vanbaalenii_PYR-1       THLASEMDDEYVSTEHLLVGLATGDADTAKLLTGHGASPQALREAFVKVR
MSMEG_0732|M.smegmatis_MC2_155      QNLATEMDDEYVSTEHLMVGLATGDSEVAKLLTGHGASPQALREAFVKVR
TH_2647|M.thermoresistible__bu      QQLATEMADEYVSTEHLLVGLASGDSDVAKILNGHGATPQALREAFAKVR
Rv0384c|M.tuberculosis_H37Rv        QQLATELDDEYVSTEHVMVGLATGDSDVAKLLTGHGASPQALREAFVKVR
Mb0391c|M.bovis_AF2122/97           QQLATELDDEYVSTEHVMVGLATGDSDVAKLLTGHGASPQALREAFVKVR
MMAR_0645|M.marinum_M               QQLATEMDDEYVSTEHVLVGLATGDSEVAKLLTGHGASPQALREAFVKVR
MUL_0127|M.ulcerans_Agy99           QQLATEMDDEYVSTEHVLVGLATGDSEVAKLLTGHGASPQALREAFVKVR
MLBr_02490|M.leprae_Br4923          QQLATEMDDEYVSTEHLMLGLAMGDSDVAKLLTGHGASPQVLREAFVKIR
MAV_4793|M.avium_104                QHLATELDDEYVSTEHLMVGLATGDSDVAKLLTGHGASPQALREAFVKVR
MAB_4265c|M.abscessus_ATCC_199      QHLATELNDDYVSTEHLLVGLATGDSDIAKLLVNHGATPQALRDAFVQVR
                                     :**:*: *:******:::*** **:: **:* .***:**.**:**.::*

Mflv_0246|M.gilvum_PYR-GCK          GSARVTNPDPEGTYQALEKYSTDLTARAREGKLDPVIGRDHEIRRVVQVL
Mvan_0659|M.vanbaalenii_PYR-1       GSARVTSPDPEGTYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL
MSMEG_0732|M.smegmatis_MC2_155      GSARVTSPDPEGTYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL
TH_2647|M.thermoresistible__bu      GSARVTTPDPEGTYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVIQVL
Rv0384c|M.tuberculosis_H37Rv        GSARVTSPEPEATYQALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL
Mb0391c|M.bovis_AF2122/97           GSARVTSPEPEATYQALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL
MMAR_0645|M.marinum_M               GSARVTSPEPEATYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL
MUL_0127|M.ulcerans_Agy99           GSARVTSPEPEATYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL
MLBr_02490|M.leprae_Br4923          GSARVTSSDPEFTYQALEKYSTDLTAQSGEGKLDPVIGRDNEIRRVVQVL
MAV_4793|M.avium_104                GSARVTSPDPEATYQALEKYSTDLTARAREGKLDPVIGRDNEIRRVVQVL
MAB_4265c|M.abscessus_ATCC_199      GSGRVTSPEPEATFQALEKYSTDLTARAREGKLDPVIGRDTEIRRVVQVL
                                    **.***..:** *:***:********:: *********** *****:***

Mflv_0246|M.gilvum_PYR-GCK          SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVVSLDMGS
Mvan_0659|M.vanbaalenii_PYR-1       SRRTKNNPVLIGEPGVGKTAIVEGLAQRIIAGDVPESLRDKTVVSLDLGS
MSMEG_0732|M.smegmatis_MC2_155      SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVIALDLGS
TH_2647|M.thermoresistible__bu      SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVIALDLGS
Rv0384c|M.tuberculosis_H37Rv        SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGS
Mb0391c|M.bovis_AF2122/97           SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGS
MMAR_0645|M.marinum_M               SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGS
MUL_0127|M.ulcerans_Agy99           SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGS
MLBr_02490|M.leprae_Br4923          SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTLVALDLGS
MAV_4793|M.avium_104                SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVIALDLGS
MAB_4265c|M.abscessus_ATCC_199      SRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRGKTVISLDLGS
                                    *****************************:*********.**:::**:**

Mflv_0246|M.gilvum_PYR-GCK          MVAGAKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGESAM
Mvan_0659|M.vanbaalenii_PYR-1       MVAGAKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGESAM
MSMEG_0732|M.smegmatis_MC2_155      MVAGAKYRGEFEERLKAVLDDIKNSAGQVITFIDELHTIVGAGATGESAM
TH_2647|M.thermoresistible__bu      MVAGSKYRGEFEERLKAVLDEIKNSAGQIITFIDELHTIVGAGATGDGSM
Rv0384c|M.tuberculosis_H37Rv        MVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM
Mb0391c|M.bovis_AF2122/97           MVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM
MMAR_0645|M.marinum_M               MVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM
MUL_0127|M.ulcerans_Agy99           MVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM
MLBr_02490|M.leprae_Br4923          MVAGAKYRGEFEQRLKVVLDDIKFSAGQIITFIDELHTIVGAGATGESAM
MAV_4793|M.avium_104                MVAGAKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAM
MAB_4265c|M.abscessus_ATCC_199      MVAGAKYRGEFEERLKAVLDEIKNSAGQLITFIDELHTIVGAGATGESAM
                                    ****:*******:***.***:** ****:*****************:.:*

Mflv_0246|M.gilvum_PYR-GCK          DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVLVGEPSV
Mvan_0659|M.vanbaalenii_PYR-1       DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVMVGEPSV
MSMEG_0732|M.smegmatis_MC2_155      DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVFVGEPSV
TH_2647|M.thermoresistible__bu      DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVYVGEPSV
Rv0384c|M.tuberculosis_H37Rv        DAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSV
Mb0391c|M.bovis_AF2122/97           DAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSV
MMAR_0645|M.marinum_M               DAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSA
MUL_0127|M.ulcerans_Agy99           DAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSA
MLBr_02490|M.leprae_Br4923          DAGNMIKPMLARGELRLVGATTLDEYRRYIEKDAALERRFQQIFVGEPSV
MAV_4793|M.avium_104                DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVFVGEPSV
MAB_4265c|M.abscessus_ATCC_199      DAGNMIKPMLARGELRLVGATTLDEYRKYIEKDAALERRFQQVLVGEPSV
                                    ***************************::*************: *****.

Mflv_0246|M.gilvum_PYR-GCK          EDTVGILRGLKDRYEVHHGVRITDSSLVAAATLSDRYITSRFLPDKAIDL
Mvan_0659|M.vanbaalenii_PYR-1       EDTVGILRGLKERYEVHHGVRITDSALVSAATLSDRYITARFLPDKAIDL
MSMEG_0732|M.smegmatis_MC2_155      EDTVGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL
TH_2647|M.thermoresistible__bu      EDTIGILRGLKERYEVHHGVRITDSALVAAATLSNRYITARFLPDKAIDL
Rv0384c|M.tuberculosis_H37Rv        EDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL
Mb0391c|M.bovis_AF2122/97           EDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL
MMAR_0645|M.marinum_M               EDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL
MUL_0127|M.ulcerans_Agy99           EDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL
MLBr_02490|M.leprae_Br4923          EDTVGILRGLKDRYEVHHGVRITDSALVAAAALSDRYITARFLPDKAIDL
MAV_4793|M.avium_104                EDTVGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDL
MAB_4265c|M.abscessus_ATCC_199      EDTIGILRGIKERYEIHHGVRITDSALVAAATLSDRYITSRFLPDKAIDL
                                    ***:*****:*:***:*********:**:**:**:****:**********

Mflv_0246|M.gilvum_PYR-GCK          VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALAKEEDAASKDRLEK
Mvan_0659|M.vanbaalenii_PYR-1       VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALEKESDAASKDRLEK
MSMEG_0732|M.smegmatis_MC2_155      VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALEKEEDEASKDRLEK
TH_2647|M.thermoresistible__bu      VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASKERLEK
Rv0384c|M.tuberculosis_H37Rv        VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASAERLAK
Mb0391c|M.bovis_AF2122/97           VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASAERLAK
MMAR_0645|M.marinum_M               VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDDASKDRLEK
MUL_0127|M.ulcerans_Agy99           VDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDDASKDRLEK
MLBr_02490|M.leprae_Br4923          VDEAASRLRMEIDSRPVEIDEVERLVRRFEIEEMALVNEEDEASKERLET
MAV_4793|M.avium_104                VDEAASRLKMEIDSRPVEIDEVERLVRRLEIEEMALAKEEDEASKERLEK
MAB_4265c|M.abscessus_ATCC_199      VDEAASRLRMEIDSRPVEIDEVERVVRRLEIEEMALSKEEDEASKQRLEK
                                    ********:***************:***:******* :*.* ** :** .

Mflv_0246|M.gilvum_PYR-GCK          LRAELADKKEQLAELTTRWQNEKSAIDVVRELKEQLESLRGEADRAERDG
Mvan_0659|M.vanbaalenii_PYR-1       LRSELADQKEKLSELTTRWQNEKGAIDVVRELKEQLEELRGAADRAERDG
MSMEG_0732|M.smegmatis_MC2_155      LRAELADHKEKLSELTTRWQNEKNAINVVRELKEQLDTLRGEADRAERDG
TH_2647|M.thermoresistible__bu      LRAELADHKEKLAELTARWQNEKKAIETVRELKEQLEALKIEAERAERDG
Rv0384c|M.tuberculosis_H37Rv        LRSELADQKEKLAELTTRWQNEKNAIEIVRDLKEQLEALRGESERAERDG
Mb0391c|M.bovis_AF2122/97           LRSELADQKEKLAELTTRWQNEKNAIEIVRDLKEQLEALRGESERAERDG
MMAR_0645|M.marinum_M               LRAELADKKEELAELTTRWQNEKNSIEIVRELKEQLDALRGESERAERDG
MUL_0127|M.ulcerans_Agy99           LRAELADKKEELAELTTRWQNEKNSIEIVRELKEQLDALRGESERAERDG
MLBr_02490|M.leprae_Br4923          LRAELADQKERLAELTARWQNEKNAIDVVRELKEQLETLRGESERAERDG
MAV_4793|M.avium_104                LRSELADQKEKLAELTTRWQNEKNAIDVVRELKEQLETLRGESDRAERDG
MAB_4265c|M.abscessus_ATCC_199      LRVELADKKERLAELTARWQNEKSSIDAVRDLKEQLETLKGESDRAERDG
                                    ** ****:**.*:***:****** :*: **:*****: *:  ::******

Mflv_0246|M.gilvum_PYR-GCK          DLAKAAELRYGRIPEVEKKLDAALPHAEARENVMLKEEVGPDDIAEVVEA
Mvan_0659|M.vanbaalenii_PYR-1       DLAKAAELRYGRIPEVEKKLDAAVPQAEARDNVMLKEEVGPDDIADVVSA
MSMEG_0732|M.smegmatis_MC2_155      DLAKAAELRYGRIPEVEKKLDAALPAAEARENLMLKEEVGPDDIAEVVEA
TH_2647|M.thermoresistible__bu      NYERVAELRYGRIPEVEKKLEAATPHAEARENVMLKEEVGPDDIAEVVSA
Rv0384c|M.tuberculosis_H37Rv        DLAKAAELRYGRIPEVEKKLDAALPQAQAREQVMLKEEVGPDDIADVVSA
Mb0391c|M.bovis_AF2122/97           DLAKAAELRYGRIPEVEKKLDAALPQAQAREQVMLKEEVGPDDIADVVSA
MMAR_0645|M.marinum_M               DLAKAAELRYGRIPEMEKKLDAAVPHAQAREQVMLKEEVGPDDIAEVVSA
MUL_0127|M.ulcerans_Agy99           DLAKAAELRYGRIPEMEKKLDAAVPHAQAREQVMLKEEVGPDDIAEVVSA
MLBr_02490|M.leprae_Br4923          DLAKAAELRYGRIPEVEKKLEAAVPTAQAREDVMLKEEVGPDDIANVVSA
MAV_4793|M.avium_104                DLAKAAELRYGRIPEVEKKLEAALPQAEARENVMLKEEVGPDDIAEVVSA
MAB_4265c|M.abscessus_ATCC_199      DLGKAAELRYGRIPELEKQLEQALPGLDHDGNVMLKEEVSPDDVADVVSA
                                    :  :.**********:**:*: * *  :   ::******.***:*:**.*

Mflv_0246|M.gilvum_PYR-GCK          WTGIPAGRMLEGETAKLLRMEEELGKRVVGQRKAVTAVSDAVRRSRAGVA
Mvan_0659|M.vanbaalenii_PYR-1       WTGIPAGRMLEGETAKLLRMEDELGKRVVGQKNAVQAVSDAVRRSRAGVA
MSMEG_0732|M.smegmatis_MC2_155      WTGIPSGRMLEGETAKLLRMEEELGKRVVGQRKAVQAVSDAVRRSRAGVA
TH_2647|M.thermoresistible__bu      WTGIPAGRMLEGEQAKLLRMEDELAKRVVGQKRAVQAVSDAVRRSRAGVA
Rv0384c|M.tuberculosis_H37Rv        WTGIPAGRLLEGETAKLLRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVS
Mb0391c|M.bovis_AF2122/97           WTGIPAGRLLEGETAKLLRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVS
MMAR_0645|M.marinum_M               WTGIPAGRMLEGETAKLLRMEDELGHRVIGQKKAVQAVSDAVRRSRAGVA
MUL_0127|M.ulcerans_Agy99           WTGIPAGRMLEGETAKLLRMEDELGHRVIGQKKAVQAVSDAVRRSRAGVA
MLBr_02490|M.leprae_Br4923          WTGIPAGRLLEGETAKLLRMEDELGKRVVGQKKAVHAVSDAVRRSRAGVA
MAV_4793|M.avium_104                WTGIPAGRMLEGETAKLLRMEDELGKRVVGQKRAVQAVSDAVRRARAGVA
MAB_4265c|M.abscessus_ATCC_199      WTGIPTGRLMEGETAKLLRMEDELGKRVVGQKKAVEAVSDAVRRARAGVA
                                    *****:**::*** *******:**.:**:**: ** ********:****:

Mflv_0246|M.gilvum_PYR-GCK          DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS
Mvan_0659|M.vanbaalenii_PYR-1       DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS
MSMEG_0732|M.smegmatis_MC2_155      DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS
TH_2647|M.thermoresistible__bu      DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYSEKHS
Rv0384c|M.tuberculosis_H37Rv        DPNRPTGAFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYGEKHT
Mb0391c|M.bovis_AF2122/97           DPNRPTGAFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYGEKHT
MMAR_0645|M.marinum_M               DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS
MUL_0127|M.ulcerans_Agy99           DPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYGEKHS
MLBr_02490|M.leprae_Br4923          DPNRPTGSFLFLGPTGVGKTELAKALADFLFDDQRAMVRVDMSEYGEKHS
MAV_4793|M.avium_104                DPNRPTGSFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYGEKHS
MAB_4265c|M.abscessus_ATCC_199      DPNRPTGSFLFLGPTGVGKTELAKALADFLFDDEHAMVRIDMSEYGEKHS
                                    *******:*:*****************:*****::****:*****.***:

Mflv_0246|M.gilvum_PYR-GCK          VARLVGAPPGYVGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ
Mvan_0659|M.vanbaalenii_PYR-1       VARLVGAPPGYVGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ
MSMEG_0732|M.smegmatis_MC2_155      VARLVGAPPGYIGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ
TH_2647|M.thermoresistible__bu      VARLVGAPPGYVGYDQGGQLTEAVRRRPYTVILFDEIEKAHQDVFDILLQ
Rv0384c|M.tuberculosis_H37Rv        VARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQ
Mb0391c|M.bovis_AF2122/97           VARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQ
MMAR_0645|M.marinum_M               VARLVGAPPGYIGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ
MUL_0127|M.ulcerans_Agy99           VARLVGAPPGYIGYDHGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ
MLBr_02490|M.leprae_Br4923          VARLVGAPPGYIGHDQGGQLTEAVRRRPYTVVLFDEVEKAHSDVFDVLLQ
MAV_4793|M.avium_104                VARLVGAPPGYIGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQ
MAB_4265c|M.abscessus_ATCC_199      VARLVGAPPGYVGYDAGGQLTEAVRRRPYTVVLFDEVEKAHPDVFDVLLQ
                                    ****:******:*:: ***************:****:**** ****:***

Mflv_0246|M.gilvum_PYR-GCK          VLDEGRLTDGQGRTVDFRNTILILTSNLGAGGSEEQVMAAVRAAFKPEFI
Mvan_0659|M.vanbaalenii_PYR-1       VLDEGRLTDGQGRTVDFRNTILILTSNLGAGGNEEQVMAAVRAAFKPEFI
MSMEG_0732|M.smegmatis_MC2_155      VLDEGRLTDGQGRTVDFRNTILILTSNLGAGGNEDQVMAAVRSAFKPEFI
TH_2647|M.thermoresistible__bu      VLDDGRLTDGQGRTVDFRNTILILTSNLGAGGSEEQVMAAVRAHFKPEFI
Rv0384c|M.tuberculosis_H37Rv        VLDEGRLTDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRATFKPEFI
Mb0391c|M.bovis_AF2122/97           VLDEGRLTDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRATFKPEFI
MMAR_0645|M.marinum_M               VLDEGRLTDGQGRTVDFRNTILILTSNLGSGGTPDQVMAAVRAAFKPEFI
MUL_0127|M.ulcerans_Agy99           VLDEGRLTDGQGRTVDFRNTILILTSNLGSGGTPDQVMAAVRAAFKPEFI
MLBr_02490|M.leprae_Br4923          VLDEGRLTDGQGRTVDFRNTIPILTSNLGSGGSEEQVMAAVRSVFKPEFI
MAV_4793|M.avium_104                VLDEGRLTDGQGRTVDFRNTILILTSNLGSGGSEEQVMAAVRSAFKPEFI
MAB_4265c|M.abscessus_ATCC_199      VLDEGRLTDGQGRTVDFRNTILILTSNLGAGGSEEQVMAAVRAKFKPEFI
                                    ***:******:********** *******:**. :**:****: ******

Mflv_0246|M.gilvum_PYR-GCK          NRLDDVIMFDALDPEQLVSIVDIQLEQLAKRLAQRRLTLEVSLPAKKWLA
Mvan_0659|M.vanbaalenii_PYR-1       NRLDDVIMFDALNPEQLVSIVDIQLAQLQKRLAQRRLTLEVSLPAKKWLA
MSMEG_0732|M.smegmatis_MC2_155      NRLDDVIIFDGLNPEELVQIVDIQLAQLAKRLEQRRLTLEVSLPAKKWLG
TH_2647|M.thermoresistible__bu      NRLDDIIIFDGLNPEELVSIVDIQLAQLAKRLEQRRLTLQVSEPAKQWLA
Rv0384c|M.tuberculosis_H37Rv        NRLDDVLIFEGLNPEELVRIVDIQLAQLGKRLAQRRLQLQVSLPAKRWLA
Mb0391c|M.bovis_AF2122/97           NRLDDVLIFEGLNPEELVRIVDIQLAQLGKRLAQRRLQLQVSLPAKRWLA
MMAR_0645|M.marinum_M               NRLDDVLIFDALNPDELVQIVDIQLQQLDKRLAQRRLQLEVSLPAKEWLA
MUL_0127|M.ulcerans_Agy99           NRLDDVLIFDALNPDELVQIVDIQLQQLDKRLAQRRLQLEVSLPAKEWLA
MLBr_02490|M.leprae_Br4923          NRLDDVLIFDGLNPEELVRIVDIQLEQLGKRLAQRRLQLEVSLPAKRWLA
MAV_4793|M.avium_104                NRLDDVIIFHGLEPGELVQIVDIQLAQLQKRLAQRRLTLEVSLPAKQWLA
MAB_4265c|M.abscessus_ATCC_199      NRLDDVLIFDGLNPEELVQIVDIQLGQLQKRLAQRRLTLEVSAPAKKWLA
                                    *****:::*..*:* :** ****** ** *** **** *:** ***.**.

Mflv_0246|M.gilvum_PYR-GCK          ERGFDPLYGARPLRRLVQQAIGDQLARMLLSGQVHDGDVVPVNLSADGDS
Mvan_0659|M.vanbaalenii_PYR-1       ERGFDPLYGARPLRRLIQQAIGDQLAKLLLAGDVHDGDVVPVNVSPDGDS
MSMEG_0732|M.smegmatis_MC2_155      QRGFDPLYGARPLRRLVQQAIGDQLAKMLLAGEVHDGDIVPVNVSPDGES
TH_2647|M.thermoresistible__bu      QRGFDPQYGARPLRRLIQKVIGDQLAKLLLAGEVHDGDVVPVNVAPDGNS
Rv0384c|M.tuberculosis_H37Rv        QRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPDADS
Mb0391c|M.bovis_AF2122/97           QRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPDADS
MMAR_0645|M.marinum_M               QRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSADGES
MUL_0127|M.ulcerans_Agy99           QRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSADGES
MLBr_02490|M.leprae_Br4923          QHGFDPVYGARPLRRLVQQAIGDQLAKMLLAGEVHDGDTLPVNVRPDGEA
MAV_4793|M.avium_104                HRGFDPVYGARPLRRLVQQAIGDQLAKQLLAGQVHDGDTVPVNVSPDGDS
MAB_4265c|M.abscessus_ATCC_199      ARGFDPIYGARPLRRLVQQSIGDQLAKQLLAGEVHDGDVVPVNVSADGES
                                     :**** *********:*: ******: **:*:***** :***: .*.::

Mflv_0246|M.gilvum_PYR-GCK          LVLG
Mvan_0659|M.vanbaalenii_PYR-1       LVLG
MSMEG_0732|M.smegmatis_MC2_155      LVLG
TH_2647|M.thermoresistible__bu      LVLG
Rv0384c|M.tuberculosis_H37Rv        LILG
Mb0391c|M.bovis_AF2122/97           LILG
MMAR_0645|M.marinum_M               LVLG
MUL_0127|M.ulcerans_Agy99           LVFG
MLBr_02490|M.leprae_Br4923          LILG
MAV_4793|M.avium_104                LILG
MAB_4265c|M.abscessus_ATCC_199      LILG
                                    *::*