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FERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQ QAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQL LSGYQGKEAAEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNN PVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGD IILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPT VEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPDL REFDEKIADARREKESAIDAQDFEKAASLRDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNW TGIPVFKLTEAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTE LSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAH QEIYNSLLQVLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSQTGGENDYERMKQKVNDEL KKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMIGRVANQLKSKDMALELTDKAKSLLAKRGFDPVLGAR PLRRTIQREIEDQLSEKILFEEVGPGQVVTVDVDNWDGEGAGEDAKFTFTGTRKPPSEPDLAKAGAHSAG GPGPTEQ*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_5100 | clpC1 | - | 100% (848) | ATP-dependent protease ATP-binding subunit ClpC1 |
M. marinum M | MMAR_0645 | clpB | 0.0 | 47.13% (872) | endopeptidase ATP binding protein (chain B) ClpB |
M. marinum M | MMAR_2048 | clpC2 | 5e-19 | 38.51% (161) | ATP-dependent protease ATP-binding subunit ClpC2 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3627c | clpC | 0.0 | 98.11% (845) | ATP-dependent Clp protease ATP-binding subunit CLPC |
M. gilvum PYR-GCK | Mflv_1430 | - | 0.0 | 95.06% (850) | ATPase |
M. tuberculosis H37Rv | Rv3596c | clpC1 | 0.0 | 98.11% (845) | ATP-dependent protease ATP-binding subunit ClpC1 |
M. leprae Br4923 | MLBr_00235 | clpC | 0.0 | 97.17% (848) | putative ATP-dependent Clp protease |
M. abscessus ATCC 19977 | MAB_0546 | - | 0.0 | 95.16% (826) | ATP-dependent Clp protease ATP-binding subunit |
M. avium 104 | MAV_0556 | - | 0.0 | 98.17% (819) | negative regulator of genetic competence ClpC/mecB |
M. smegmatis MC2 155 | MSMEG_6091 | - | 0.0 | 96.09% (845) | negative regulator of genetic competence ClpC/mecB |
M. thermoresistible (build 8) | TH_2346 | clpC | 0.0 | 94.22% (830) | PROBABLE ATP-DEPENDENT PROTEASE ATP-BINDING SUBUNIT CLPC1 |
M. ulcerans Agy99 | MUL_4178 | clpC1 | 0.0 | 99.65% (849) | ATP-dependent protease ATP-binding subunit ClpC1 |
M. vanbaalenii PYR-1 | Mvan_5358 | - | 0.0 | 96.00% (849) | ATPase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_5100|M.marinum_M MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE MUL_4178|M.ulcerans_Agy99 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE Mb3627c|M.bovis_AF2122/97 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE Rv3596c|M.tuberculosis_H37Rv MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE MLBr_00235|M.leprae_Br4923 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLD MAV_0556|M.avium_104 ---------------------MLNHNYIGTEHILLGLIHEGEGVAAKSLE Mflv_1430|M.gilvum_PYR-GCK MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE Mvan_5358|M.vanbaalenii_PYR-1 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE MAB_0546|M.abscessus_ATCC_1997 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE MSMEG_6091|M.smegmatis_MC2_155 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE TH_2346|M.thermoresistible__bu MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE ****************************: MMAR_5100|M.marinum_M SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH MUL_4178|M.ulcerans_Agy99 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH Mb3627c|M.bovis_AF2122/97 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH Rv3596c|M.tuberculosis_H37Rv SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH MLBr_00235|M.leprae_Br4923 SLGISLEAVRSQVEDIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH MAV_0556|M.avium_104 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH Mflv_1430|M.gilvum_PYR-GCK SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH Mvan_5358|M.vanbaalenii_PYR-1 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH MAB_0546|M.abscessus_ATCC_1997 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH MSMEG_6091|M.smegmatis_MC2_155 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH TH_2346|M.thermoresistible__bu SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH *******.******:*********************************** MMAR_5100|M.marinum_M NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA MUL_4178|M.ulcerans_Agy99 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA Mb3627c|M.bovis_AF2122/97 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA Rv3596c|M.tuberculosis_H37Rv NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA MLBr_00235|M.leprae_Br4923 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA MAV_0556|M.avium_104 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA Mflv_1430|M.gilvum_PYR-GCK NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGRET Mvan_5358|M.vanbaalenii_PYR-1 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKET MAB_0546|M.abscessus_ATCC_1997 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKET MSMEG_6091|M.smegmatis_MC2_155 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA TH_2346|M.thermoresistible__bu NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA ***********************************************:*: MMAR_5100|M.marinum_M AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV MUL_4178|M.ulcerans_Agy99 AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV Mb3627c|M.bovis_AF2122/97 AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV Rv3596c|M.tuberculosis_H37Rv AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV MLBr_00235|M.leprae_Br4923 AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMESKLDPVIGREKEIERV MAV_0556|M.avium_104 AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV Mflv_1430|M.gilvum_PYR-GCK AEAGTGGRGGEAGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV Mvan_5358|M.vanbaalenii_PYR-1 AEAGTGGRGGEAGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV MAB_0546|M.abscessus_ATCC_1997 AESGTGGRGGEAGTPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV MSMEG_6091|M.smegmatis_MC2_155 AEAGTGGRGGESGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV TH_2346|M.thermoresistible__bu AEAGTGGRGGESGNPSTSLVLDQFGRNLTQAAAEGKLDPVIGREKEVERI **:********:*.*************** ** *.***********:**: MMAR_5100|M.marinum_M MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL MUL_4178|M.ulcerans_Agy99 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL Mb3627c|M.bovis_AF2122/97 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL Rv3596c|M.tuberculosis_H37Rv MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL MLBr_00235|M.leprae_Br4923 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL MAV_0556|M.avium_104 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGQVPETLKDKQLYTL Mflv_1430|M.gilvum_PYR-GCK MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGDVPETLKDKQLYTL Mvan_5358|M.vanbaalenii_PYR-1 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL MAB_0546|M.abscessus_ATCC_1997 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKNKQLYTL MSMEG_6091|M.smegmatis_MC2_155 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL TH_2346|M.thermoresistible__bu MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVAGEVPETLKDKQLYTL ********************************** *:******:****** MMAR_5100|M.marinum_M DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG MUL_4178|M.ulcerans_Agy99 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG Mb3627c|M.bovis_AF2122/97 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG Rv3596c|M.tuberculosis_H37Rv DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG MLBr_00235|M.leprae_Br4923 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG MAV_0556|M.avium_104 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG Mflv_1430|M.gilvum_PYR-GCK DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG Mvan_5358|M.vanbaalenii_PYR-1 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG MAB_0546|M.abscessus_ATCC_1997 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG MSMEG_6091|M.smegmatis_MC2_155 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG TH_2346|M.thermoresistible__bu DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG ************************************************** MMAR_5100|M.marinum_M AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP MUL_4178|M.ulcerans_Agy99 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP Mb3627c|M.bovis_AF2122/97 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP Rv3596c|M.tuberculosis_H37Rv AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP MLBr_00235|M.leprae_Br4923 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP MAV_0556|M.avium_104 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP Mflv_1430|M.gilvum_PYR-GCK AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP Mvan_5358|M.vanbaalenii_PYR-1 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP MAB_0546|M.abscessus_ATCC_1997 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP MSMEG_6091|M.smegmatis_MC2_155 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP TH_2346|M.thermoresistible__bu AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP ************************************************** MMAR_5100|M.marinum_M TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI MUL_4178|M.ulcerans_Agy99 TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI Mb3627c|M.bovis_AF2122/97 TVEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAI Rv3596c|M.tuberculosis_H37Rv TVEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAI MLBr_00235|M.leprae_Br4923 TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI MAV_0556|M.avium_104 TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAI Mflv_1430|M.gilvum_PYR-GCK TVAHTIEILKGLRDRYEAHHRVSITDGAIAAAATLADRYINDRFLPDKAI Mvan_5358|M.vanbaalenii_PYR-1 TVEHTIEILKGLRDRYEAHHRVSITDSALVAAATLADRYINDRFLPDKAI MAB_0546|M.abscessus_ATCC_1997 TVEHTIEILKGLRDRYEAHHRVSITDGALVAAATLADRYINDRFLPDKAI MSMEG_6091|M.smegmatis_MC2_155 TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI TH_2346|M.thermoresistible__bu TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAI ** ***********************.*:.*************:****** MMAR_5100|M.marinum_M DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL MUL_4178|M.ulcerans_Agy99 DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL Mb3627c|M.bovis_AF2122/97 DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL Rv3596c|M.tuberculosis_H37Rv DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL MLBr_00235|M.leprae_Br4923 DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL MAV_0556|M.avium_104 DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL Mflv_1430|M.gilvum_PYR-GCK DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL Mvan_5358|M.vanbaalenii_PYR-1 DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL MAB_0546|M.abscessus_ATCC_1997 DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAARL MSMEG_6091|M.smegmatis_MC2_155 DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAAAL TH_2346|M.thermoresistible__bu DLIDEAGARMRIRRMTAPPDLREFDEKIAETRREKESAIDAQDFEKAAAL *****************************::***************** * MMAR_5100|M.marinum_M RDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT MUL_4178|M.ulcerans_Agy99 RDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT Mb3627c|M.bovis_AF2122/97 RDREKTLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT Rv3596c|M.tuberculosis_H37Rv RDREKTLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT MLBr_00235|M.leprae_Br4923 RDREKQLVAQRAEREKQWRSGDLDVIAEVDDEQIAEVLGNWTGIPVFKLT MAV_0556|M.avium_104 RDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT Mflv_1430|M.gilvum_PYR-GCK RDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT Mvan_5358|M.vanbaalenii_PYR-1 RDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT MAB_0546|M.abscessus_ATCC_1997 RDSEKQLVAQRADREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT MSMEG_6091|M.smegmatis_MC2_155 RDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT TH_2346|M.thermoresistible__bu RDQEKQLVAQRAEREKQWRAGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT ** ** ******:******:*****:************************ MMAR_5100|M.marinum_M EAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI MUL_4178|M.ulcerans_Agy99 EAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI Mb3627c|M.bovis_AF2122/97 EAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI Rv3596c|M.tuberculosis_H37Rv EAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI MLBr_00235|M.leprae_Br4923 EAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI MAV_0556|M.avium_104 EAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI Mflv_1430|M.gilvum_PYR-GCK EEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI Mvan_5358|M.vanbaalenii_PYR-1 EEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI MAB_0546|M.abscessus_ATCC_1997 EEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPRRPSGSFI MSMEG_6091|M.smegmatis_MC2_155 EEETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI TH_2346|M.thermoresistible__bu EAETTRLLRMEEELHKRIIGQEDAVRAVSKAIRRTRAGLKDPKRPSGSFI * *********:*************:****************:******* MMAR_5100|M.marinum_M FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG MUL_4178|M.ulcerans_Agy99 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG Mb3627c|M.bovis_AF2122/97 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG Rv3596c|M.tuberculosis_H37Rv FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG MLBr_00235|M.leprae_Br4923 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG MAV_0556|M.avium_104 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG Mflv_1430|M.gilvum_PYR-GCK FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG Mvan_5358|M.vanbaalenii_PYR-1 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG MAB_0546|M.abscessus_ATCC_1997 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG MSMEG_6091|M.smegmatis_MC2_155 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG TH_2346|M.thermoresistible__bu FAGPSGVGKTELSKALAEFLFGDEDALIQIDMGEYHDRFTASRLFGAPPG *****************:*****:**********:*************** MMAR_5100|M.marinum_M YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG MUL_4178|M.ulcerans_Agy99 YVGYEEGGQLTEKVRRKPFSVALFDEIEKAHQEISNSLLQVLEDGRLTDG Mb3627c|M.bovis_AF2122/97 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG Rv3596c|M.tuberculosis_H37Rv YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG MLBr_00235|M.leprae_Br4923 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG MAV_0556|M.avium_104 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG Mflv_1430|M.gilvum_PYR-GCK YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG Mvan_5358|M.vanbaalenii_PYR-1 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG MAB_0546|M.abscessus_ATCC_1997 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQVLEDGRLTDG MSMEG_6091|M.smegmatis_MC2_155 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG TH_2346|M.thermoresistible__bu YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQVLEDGRLTDG *********************.************ *:************* MMAR_5100|M.marinum_M QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSQTGGENDYERMKQKVNDE MUL_4178|M.ulcerans_Agy99 QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSQTGGENDYERMKQKVNDE Mb3627c|M.bovis_AF2122/97 QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSKGGGENDYERMKQKVNDE Rv3596c|M.tuberculosis_H37Rv QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSKGGGENDYERMKQKVNDE MLBr_00235|M.leprae_Br4923 QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGSGENDYERMKQKVNDE MAV_0556|M.avium_104 QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGGGENNYERMKQKVNDE Mflv_1430|M.gilvum_PYR-GCK QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVHDE Mvan_5358|M.vanbaalenii_PYR-1 QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVHDE MAB_0546|M.abscessus_ATCC_1997 QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSEGAAGSNYERMKQKVHDE MSMEG_6091|M.smegmatis_MC2_155 QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSQGGSENNYERMKQKVHDE TH_2346|M.thermoresistible__bu QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSQGGSENNYERMKQKVHDE *************************.*****:: .. .:********:** MMAR_5100|M.marinum_M LKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMIGRVANQLKS-KDMAL MUL_4178|M.ulcerans_Agy99 LKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMIGRVANQLKSSKDMAL Mb3627c|M.bovis_AF2122/97 LKKHFRPEFLNRIDDIIVFHQLTREEIIRMVDLMISRVAGQLKS-KDMAL Rv3596c|M.tuberculosis_H37Rv LKKHFRPEFLNRIDDIIVFHQLTREEIIRMVDLMISRVAGQLKS-KDMAL MLBr_00235|M.leprae_Br4923 LKKHFRPEFLNRIDDIIVFHQLSRDEIIRMVDLMISRVANQLKV-KDMTL MAV_0556|M.avium_104 LKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMITRVAGQLKS-KDMDL Mflv_1430|M.gilvum_PYR-GCK LKKHFRPEFLNRIDDIIVFHQLTQDEIIQMVDLMIGRVGNQLKA-KDMAM Mvan_5358|M.vanbaalenii_PYR-1 LKKHFRPEFLNRIDDIIVFHQLTQDEIIKMVDLMIGRVSKQLAA-KDMTM MAB_0546|M.abscessus_ATCC_1997 LKKHFRPEFLNRIDDIIVFEQLTQEQIIEMVDLMIGRVGKQLKT-KDMAM MSMEG_6091|M.smegmatis_MC2_155 LKKHFRPEFLNRIDDIIVFHQLTQDEIIQMVDLMIGRVSNQLKT-KDMAL TH_2346|M.thermoresistible__bu LKKHFRPEFLNRIDDIIVFHQLTQEQIIQMVDLMIDRVRNQLKA-KDMDL *******************.**::::**.****** ** ** *** : MMAR_5100|M.marinum_M ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV MUL_4178|M.ulcerans_Agy99 ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV Mb3627c|M.bovis_AF2122/97 VLTDAAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV Rv3596c|M.tuberculosis_H37Rv VLTDAAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV MLBr_00235|M.leprae_Br4923 ELTNKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV MAV_0556|M.avium_104 VLTDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQI Mflv_1430|M.gilvum_PYR-GCK ELTPKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEELGPGQL Mvan_5358|M.vanbaalenii_PYR-1 ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQL MAB_0546|M.abscessus_ATCC_1997 ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDALSEKILFNEVGPGEL MSMEG_6091|M.smegmatis_MC2_155 ELSDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEIGPGQL TH_2346|M.thermoresistible__bu QLTDKAKQLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEELRPGQL *: ** ************************** *******:*: **:: MMAR_5100|M.marinum_M VTVDVDNWDGEGAGEDAKF------------------------------- MUL_4178|M.ulcerans_Agy99 VTVDVDNWDGEGAGEDAKF------------------------------- Mb3627c|M.bovis_AF2122/97 VTVDVDNWDGEGPGEDAVF------------------------------- Rv3596c|M.tuberculosis_H37Rv VTVDVDNWDGEGPGEDAVF------------------------------- MLBr_00235|M.leprae_Br4923 VTVDVDNWDGEGPGEDVKF------------------------------- MAV_0556|M.avium_104 VTVDVDNWDGESAGEDAVF------------------------------- Mflv_1430|M.gilvum_PYR-GCK VTVDVENWDGEGQGEDAVF------------------------------- Mvan_5358|M.vanbaalenii_PYR-1 VTVDVEGWDGEGAGEDAKF------------------------------- MAB_0546|M.abscessus_ATCC_1997 VTVDVENWDGESAGEDAKF------------------------------- MSMEG_6091|M.smegmatis_MC2_155 VTVDVEGWDGEGQGEDAKF------------------------------- TH_2346|M.thermoresistible__bu ITVDVENWDGEGAGEDAXXXPTPPTGPAADVLNQATRVVPPAAPPSGTSA :****:.****. ***. MMAR_5100|M.marinum_M --------------------TFTGTRKPPSEPDLAKAGAHSAGGPGPTEQ MUL_4178|M.ulcerans_Agy99 --------------------TFTGTRKPPSEPDLAKAGAHSAGGPGPTEQ Mb3627c|M.bovis_AF2122/97 --------------------TFTGTRKPPAEPDLAKAGAHSAGGPEPAAR Rv3596c|M.tuberculosis_H37Rv --------------------TFTGTRKPPAEPDLAKAGAHSAGGPEPAAR MLBr_00235|M.leprae_Br4923 --------------------TFTGIRKPSTEPDLAKAGVHSAGGPEPVEQ MAV_0556|M.avium_104 --------------------TFTGTRKPPAEPDLAKAGAHSADPQ----- Mflv_1430|M.gilvum_PYR-GCK --------------------TFSGARKPVEVAEPDLAQAGAGGAGPAAE- Mvan_5358|M.vanbaalenii_PYR-1 --------------------TFIGTKKPVKIEEPDLAQAGAAGGPSAAE- MAB_0546|M.abscessus_ATCC_1997 --------------------TFVGRPKPALVAG---EEPAADLAASASE- MSMEG_6091|M.smegmatis_MC2_155 --------------------TFSGGPKRAETAEPDLAGAGAAGAPTAGTE TH_2346|M.thermoresistible__bu ARSGLLPSLLLPLQTTANTVTSVVPPPPPPAPGTPEAAVLETASGSASAA * MMAR_5100|M.marinum_M -------------------------------------------------- MUL_4178|M.ulcerans_Agy99 -------------------------------------------------- Mb3627c|M.bovis_AF2122/97 -------------------------------------------------- Rv3596c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00235|M.leprae_Br4923 -------------------------------------------------- MAV_0556|M.avium_104 -------------------------------------------------- Mflv_1430|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5358|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0546|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_6091|M.smegmatis_MC2_155 -------------------------------------------------- TH_2346|M.thermoresistible__bu MPGVAAATSTLFSPPELNLPSIPGVGIPLPNRLSLPTDGICEGLGWSAGK MMAR_5100|M.marinum_M ----------------------- MUL_4178|M.ulcerans_Agy99 ----------------------- Mb3627c|M.bovis_AF2122/97 ----------------------- Rv3596c|M.tuberculosis_H37Rv ----------------------- MLBr_00235|M.leprae_Br4923 ----------------------- MAV_0556|M.avium_104 ----------------------- Mflv_1430|M.gilvum_PYR-GCK ----------------------- Mvan_5358|M.vanbaalenii_PYR-1 ----------------------- MAB_0546|M.abscessus_ATCC_1997 ----------------------- MSMEG_6091|M.smegmatis_MC2_155 ----------------------- TH_2346|M.thermoresistible__bu SDGQGAEVPAAPVPADRRDRWDR