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M. leprae Br4923 MLBr_00235 (clpC)

annotation: putative ATP-dependent Clp protease
coordinates: 306018 - 308564
length: 848

MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLDSLGISLEAVRSQVEDIIGQG
QQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQ
LLSGYQGKEAAEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMESKLDPVIGREKEIERVMQVLSRRTKN
NPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRG
DIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPD
LREFDEKIAEARREKESAIDAQDFEKAASLRDREKQLVAQRAEREKQWRSGDLDVIAEVDDEQIAEVLGN
WTGIPVFKLTEAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKA
HQEIYNSLLQVLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGSGENDYERMKQKVNDE
LKKHFRPEFLNRIDDIIVFHQLSRDEIIRMVDLMISRVANQLKVKDMTLELTNKAKALLAKRGFDPVLGA
RPLRRTIQREIEDQLSEKILFEEVGPGQVVTVDVDNWDGEGPGEDVKFTFTGIRKPSTEPDLAKAGVHSA
GGPEPVEQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00235clpC-100% (848)putative ATP-dependent Clp protease
M. leprae Br4923MLBr_02490clpB0.045.58% (871) heat shock protein
M. leprae Br4923MLBr_01536-2e-0625.00% (276) hypothetical protein MLBr_01536

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3627cclpC0.097.16% (845) ATP-dependent Clp protease ATP-binding subunit CLPC
M. gilvum PYR-GCKMflv_1430-0.094.42% (843) ATPase
M. tuberculosis H37RvRv3596cclpC10.097.16% (845) ATP-dependent protease ATP-binding subunit ClpC1
M. abscessus ATCC 19977MAB_0546-0.093.35% (827) ATP-dependent Clp protease ATP-binding subunit
M. marinum MMMAR_5100clpC10.097.17% (848) ATP-dependent protease ATP-binding subunit ClpC1
M. avium 104MAV_0556-0.096.83% (819) negative regulator of genetic competence ClpC/mecB
M. smegmatis MC2 155MSMEG_6091-0.094.79% (845) negative regulator of genetic competence ClpC/mecB
M. thermoresistible (build 8)TH_2346clpC0.093.12% (829) PROBABLE ATP-DEPENDENT PROTEASE ATP-BINDING SUBUNIT CLPC1
M. ulcerans Agy99MUL_4178clpC10.096.82% (849) ATP-dependent protease ATP-binding subunit ClpC1
M. vanbaalenii PYR-1Mvan_5358-0.094.46% (849) ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3627c|M.bovis_AF2122/97           MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
Rv3596c|M.tuberculosis_H37Rv        MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
MLBr_00235|M.leprae_Br4923          MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLD
MMAR_5100|M.marinum_M               MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
MUL_4178|M.ulcerans_Agy99           MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
MAV_0556|M.avium_104                ---------------------MLNHNYIGTEHILLGLIHEGEGVAAKSLE
Mflv_1430|M.gilvum_PYR-GCK          MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
Mvan_5358|M.vanbaalenii_PYR-1       MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
MAB_0546|M.abscessus_ATCC_1997      MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
MSMEG_6091|M.smegmatis_MC2_155      MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
TH_2346|M.thermoresistible__bu      MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
                                                         ****************************:

Mb3627c|M.bovis_AF2122/97           SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
Rv3596c|M.tuberculosis_H37Rv        SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
MLBr_00235|M.leprae_Br4923          SLGISLEAVRSQVEDIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
MMAR_5100|M.marinum_M               SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
MUL_4178|M.ulcerans_Agy99           SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
MAV_0556|M.avium_104                SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
Mflv_1430|M.gilvum_PYR-GCK          SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
Mvan_5358|M.vanbaalenii_PYR-1       SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
MAB_0546|M.abscessus_ATCC_1997      SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
MSMEG_6091|M.smegmatis_MC2_155      SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
TH_2346|M.thermoresistible__bu      SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
                                    *******.******:***********************************

Mb3627c|M.bovis_AF2122/97           NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
Rv3596c|M.tuberculosis_H37Rv        NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
MLBr_00235|M.leprae_Br4923          NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
MMAR_5100|M.marinum_M               NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
MUL_4178|M.ulcerans_Agy99           NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
MAV_0556|M.avium_104                NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
Mflv_1430|M.gilvum_PYR-GCK          NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGRET
Mvan_5358|M.vanbaalenii_PYR-1       NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKET
MAB_0546|M.abscessus_ATCC_1997      NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKET
MSMEG_6091|M.smegmatis_MC2_155      NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
TH_2346|M.thermoresistible__bu      NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
                                    ***********************************************:*:

Mb3627c|M.bovis_AF2122/97           AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
Rv3596c|M.tuberculosis_H37Rv        AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
MLBr_00235|M.leprae_Br4923          AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMESKLDPVIGREKEIERV
MMAR_5100|M.marinum_M               AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
MUL_4178|M.ulcerans_Agy99           AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
MAV_0556|M.avium_104                AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
Mflv_1430|M.gilvum_PYR-GCK          AEAGTGGRGGEAGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
Mvan_5358|M.vanbaalenii_PYR-1       AEAGTGGRGGEAGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
MAB_0546|M.abscessus_ATCC_1997      AESGTGGRGGEAGTPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
MSMEG_6091|M.smegmatis_MC2_155      AEAGTGGRGGESGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
TH_2346|M.thermoresistible__bu      AEAGTGGRGGESGNPSTSLVLDQFGRNLTQAAAEGKLDPVIGREKEVERI
                                    **:********:*.*************** ** *.***********:**:

Mb3627c|M.bovis_AF2122/97           MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
Rv3596c|M.tuberculosis_H37Rv        MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
MLBr_00235|M.leprae_Br4923          MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
MMAR_5100|M.marinum_M               MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
MUL_4178|M.ulcerans_Agy99           MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
MAV_0556|M.avium_104                MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGQVPETLKDKQLYTL
Mflv_1430|M.gilvum_PYR-GCK          MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGDVPETLKDKQLYTL
Mvan_5358|M.vanbaalenii_PYR-1       MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
MAB_0546|M.abscessus_ATCC_1997      MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKNKQLYTL
MSMEG_6091|M.smegmatis_MC2_155      MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
TH_2346|M.thermoresistible__bu      MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVAGEVPETLKDKQLYTL
                                    ********************************** *:******:******

Mb3627c|M.bovis_AF2122/97           DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
Rv3596c|M.tuberculosis_H37Rv        DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
MLBr_00235|M.leprae_Br4923          DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
MMAR_5100|M.marinum_M               DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
MUL_4178|M.ulcerans_Agy99           DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
MAV_0556|M.avium_104                DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
Mflv_1430|M.gilvum_PYR-GCK          DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
Mvan_5358|M.vanbaalenii_PYR-1       DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
MAB_0546|M.abscessus_ATCC_1997      DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
MSMEG_6091|M.smegmatis_MC2_155      DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
TH_2346|M.thermoresistible__bu      DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
                                    **************************************************

Mb3627c|M.bovis_AF2122/97           AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
Rv3596c|M.tuberculosis_H37Rv        AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
MLBr_00235|M.leprae_Br4923          AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
MMAR_5100|M.marinum_M               AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
MUL_4178|M.ulcerans_Agy99           AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
MAV_0556|M.avium_104                AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
Mflv_1430|M.gilvum_PYR-GCK          AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
Mvan_5358|M.vanbaalenii_PYR-1       AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
MAB_0546|M.abscessus_ATCC_1997      AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
MSMEG_6091|M.smegmatis_MC2_155      AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
TH_2346|M.thermoresistible__bu      AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
                                    **************************************************

Mb3627c|M.bovis_AF2122/97           TVEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAI
Rv3596c|M.tuberculosis_H37Rv        TVEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAI
MLBr_00235|M.leprae_Br4923          TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI
MMAR_5100|M.marinum_M               TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI
MUL_4178|M.ulcerans_Agy99           TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI
MAV_0556|M.avium_104                TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAI
Mflv_1430|M.gilvum_PYR-GCK          TVAHTIEILKGLRDRYEAHHRVSITDGAIAAAATLADRYINDRFLPDKAI
Mvan_5358|M.vanbaalenii_PYR-1       TVEHTIEILKGLRDRYEAHHRVSITDSALVAAATLADRYINDRFLPDKAI
MAB_0546|M.abscessus_ATCC_1997      TVEHTIEILKGLRDRYEAHHRVSITDGALVAAATLADRYINDRFLPDKAI
MSMEG_6091|M.smegmatis_MC2_155      TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI
TH_2346|M.thermoresistible__bu      TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAI
                                    ** ***********************.*:.*************:******

Mb3627c|M.bovis_AF2122/97           DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL
Rv3596c|M.tuberculosis_H37Rv        DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL
MLBr_00235|M.leprae_Br4923          DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL
MMAR_5100|M.marinum_M               DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL
MUL_4178|M.ulcerans_Agy99           DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL
MAV_0556|M.avium_104                DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL
Mflv_1430|M.gilvum_PYR-GCK          DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL
Mvan_5358|M.vanbaalenii_PYR-1       DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL
MAB_0546|M.abscessus_ATCC_1997      DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAARL
MSMEG_6091|M.smegmatis_MC2_155      DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAAAL
TH_2346|M.thermoresistible__bu      DLIDEAGARMRIRRMTAPPDLREFDEKIAETRREKESAIDAQDFEKAAAL
                                    *****************************::***************** *

Mb3627c|M.bovis_AF2122/97           RDREKTLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
Rv3596c|M.tuberculosis_H37Rv        RDREKTLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
MLBr_00235|M.leprae_Br4923          RDREKQLVAQRAEREKQWRSGDLDVIAEVDDEQIAEVLGNWTGIPVFKLT
MMAR_5100|M.marinum_M               RDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
MUL_4178|M.ulcerans_Agy99           RDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
MAV_0556|M.avium_104                RDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
Mflv_1430|M.gilvum_PYR-GCK          RDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
Mvan_5358|M.vanbaalenii_PYR-1       RDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
MAB_0546|M.abscessus_ATCC_1997      RDSEKQLVAQRADREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
MSMEG_6091|M.smegmatis_MC2_155      RDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
TH_2346|M.thermoresistible__bu      RDQEKQLVAQRAEREKQWRAGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
                                    ** ** ******:******:*****:************************

Mb3627c|M.bovis_AF2122/97           EAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
Rv3596c|M.tuberculosis_H37Rv        EAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
MLBr_00235|M.leprae_Br4923          EAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
MMAR_5100|M.marinum_M               EAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
MUL_4178|M.ulcerans_Agy99           EAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
MAV_0556|M.avium_104                EAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
Mflv_1430|M.gilvum_PYR-GCK          EEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
Mvan_5358|M.vanbaalenii_PYR-1       EEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
MAB_0546|M.abscessus_ATCC_1997      EEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPRRPSGSFI
MSMEG_6091|M.smegmatis_MC2_155      EEETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
TH_2346|M.thermoresistible__bu      EAETTRLLRMEEELHKRIIGQEDAVRAVSKAIRRTRAGLKDPKRPSGSFI
                                    * *********:*************:****************:*******

Mb3627c|M.bovis_AF2122/97           FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
Rv3596c|M.tuberculosis_H37Rv        FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
MLBr_00235|M.leprae_Br4923          FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
MMAR_5100|M.marinum_M               FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
MUL_4178|M.ulcerans_Agy99           FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
MAV_0556|M.avium_104                FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
Mflv_1430|M.gilvum_PYR-GCK          FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
Mvan_5358|M.vanbaalenii_PYR-1       FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
MAB_0546|M.abscessus_ATCC_1997      FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
MSMEG_6091|M.smegmatis_MC2_155      FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
TH_2346|M.thermoresistible__bu      FAGPSGVGKTELSKALAEFLFGDEDALIQIDMGEYHDRFTASRLFGAPPG
                                    *****************:*****:**********:***************

Mb3627c|M.bovis_AF2122/97           YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
Rv3596c|M.tuberculosis_H37Rv        YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
MLBr_00235|M.leprae_Br4923          YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
MMAR_5100|M.marinum_M               YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
MUL_4178|M.ulcerans_Agy99           YVGYEEGGQLTEKVRRKPFSVALFDEIEKAHQEISNSLLQVLEDGRLTDG
MAV_0556|M.avium_104                YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
Mflv_1430|M.gilvum_PYR-GCK          YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
Mvan_5358|M.vanbaalenii_PYR-1       YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
MAB_0546|M.abscessus_ATCC_1997      YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQVLEDGRLTDG
MSMEG_6091|M.smegmatis_MC2_155      YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
TH_2346|M.thermoresistible__bu      YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQVLEDGRLTDG
                                    *********************.************ *:*************

Mb3627c|M.bovis_AF2122/97           QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSKGGGENDYERMKQKVNDE
Rv3596c|M.tuberculosis_H37Rv        QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSKGGGENDYERMKQKVNDE
MLBr_00235|M.leprae_Br4923          QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGSGENDYERMKQKVNDE
MMAR_5100|M.marinum_M               QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSQTGGENDYERMKQKVNDE
MUL_4178|M.ulcerans_Agy99           QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSQTGGENDYERMKQKVNDE
MAV_0556|M.avium_104                QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGGGENNYERMKQKVNDE
Mflv_1430|M.gilvum_PYR-GCK          QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVHDE
Mvan_5358|M.vanbaalenii_PYR-1       QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVHDE
MAB_0546|M.abscessus_ATCC_1997      QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSEGAAGSNYERMKQKVHDE
MSMEG_6091|M.smegmatis_MC2_155      QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSQGGSENNYERMKQKVHDE
TH_2346|M.thermoresistible__bu      QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSQGGSENNYERMKQKVHDE
                                    *************************.*****:: .. .:********:**

Mb3627c|M.bovis_AF2122/97           LKKHFRPEFLNRIDDIIVFHQLTREEIIRMVDLMISRVAGQLKS-KDMAL
Rv3596c|M.tuberculosis_H37Rv        LKKHFRPEFLNRIDDIIVFHQLTREEIIRMVDLMISRVAGQLKS-KDMAL
MLBr_00235|M.leprae_Br4923          LKKHFRPEFLNRIDDIIVFHQLSRDEIIRMVDLMISRVANQLKV-KDMTL
MMAR_5100|M.marinum_M               LKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMIGRVANQLKS-KDMAL
MUL_4178|M.ulcerans_Agy99           LKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMIGRVANQLKSSKDMAL
MAV_0556|M.avium_104                LKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMITRVAGQLKS-KDMDL
Mflv_1430|M.gilvum_PYR-GCK          LKKHFRPEFLNRIDDIIVFHQLTQDEIIQMVDLMIGRVGNQLKA-KDMAM
Mvan_5358|M.vanbaalenii_PYR-1       LKKHFRPEFLNRIDDIIVFHQLTQDEIIKMVDLMIGRVSKQLAA-KDMTM
MAB_0546|M.abscessus_ATCC_1997      LKKHFRPEFLNRIDDIIVFEQLTQEQIIEMVDLMIGRVGKQLKT-KDMAM
MSMEG_6091|M.smegmatis_MC2_155      LKKHFRPEFLNRIDDIIVFHQLTQDEIIQMVDLMIGRVSNQLKT-KDMAL
TH_2346|M.thermoresistible__bu      LKKHFRPEFLNRIDDIIVFHQLTQEQIIQMVDLMIDRVRNQLKA-KDMDL
                                    *******************.**::::**.****** **  **   *** :

Mb3627c|M.bovis_AF2122/97           VLTDAAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV
Rv3596c|M.tuberculosis_H37Rv        VLTDAAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV
MLBr_00235|M.leprae_Br4923          ELTNKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV
MMAR_5100|M.marinum_M               ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV
MUL_4178|M.ulcerans_Agy99           ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV
MAV_0556|M.avium_104                VLTDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQI
Mflv_1430|M.gilvum_PYR-GCK          ELTPKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEELGPGQL
Mvan_5358|M.vanbaalenii_PYR-1       ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQL
MAB_0546|M.abscessus_ATCC_1997      ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDALSEKILFNEVGPGEL
MSMEG_6091|M.smegmatis_MC2_155      ELSDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEIGPGQL
TH_2346|M.thermoresistible__bu      QLTDKAKQLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEELRPGQL
                                     *:  ** ************************** *******:*: **::

Mb3627c|M.bovis_AF2122/97           VTVDVDNWDGEGPGEDAVF-------------------------------
Rv3596c|M.tuberculosis_H37Rv        VTVDVDNWDGEGPGEDAVF-------------------------------
MLBr_00235|M.leprae_Br4923          VTVDVDNWDGEGPGEDVKF-------------------------------
MMAR_5100|M.marinum_M               VTVDVDNWDGEGAGEDAKF-------------------------------
MUL_4178|M.ulcerans_Agy99           VTVDVDNWDGEGAGEDAKF-------------------------------
MAV_0556|M.avium_104                VTVDVDNWDGESAGEDAVF-------------------------------
Mflv_1430|M.gilvum_PYR-GCK          VTVDVENWDGEGQGEDAVF-------------------------------
Mvan_5358|M.vanbaalenii_PYR-1       VTVDVEGWDGEGAGEDAKF-------------------------------
MAB_0546|M.abscessus_ATCC_1997      VTVDVENWDGESAGEDAKF-------------------------------
MSMEG_6091|M.smegmatis_MC2_155      VTVDVEGWDGEGQGEDAKF-------------------------------
TH_2346|M.thermoresistible__bu      ITVDVENWDGEGAGEDAXXXPTPPTGPAADVLNQATRVVPPAAPPSGTSA
                                    :****:.****. ***.                                 

Mb3627c|M.bovis_AF2122/97           --------------------TFTGTRKPPAEPDLAKAGAHSAGGPEPAAR
Rv3596c|M.tuberculosis_H37Rv        --------------------TFTGTRKPPAEPDLAKAGAHSAGGPEPAAR
MLBr_00235|M.leprae_Br4923          --------------------TFTGIRKPSTEPDLAKAGVHSAGGPEPVEQ
MMAR_5100|M.marinum_M               --------------------TFTGTRKPPSEPDLAKAGAHSAGGPGPTEQ
MUL_4178|M.ulcerans_Agy99           --------------------TFTGTRKPPSEPDLAKAGAHSAGGPGPTEQ
MAV_0556|M.avium_104                --------------------TFTGTRKPPAEPDLAKAGAHSADPQ-----
Mflv_1430|M.gilvum_PYR-GCK          --------------------TFSGARKPVEVAEPDLAQAGAGGAGPAAE-
Mvan_5358|M.vanbaalenii_PYR-1       --------------------TFIGTKKPVKIEEPDLAQAGAAGGPSAAE-
MAB_0546|M.abscessus_ATCC_1997      --------------------TFVGRPKPALVAG---EEPAADLAASASE-
MSMEG_6091|M.smegmatis_MC2_155      --------------------TFSGGPKRAETAEPDLAGAGAAGAPTAGTE
TH_2346|M.thermoresistible__bu      ARSGLLPSLLLPLQTTANTVTSVVPPPPPPAPGTPEAAVLETASGSASAA
                                                        *                             

Mb3627c|M.bovis_AF2122/97           --------------------------------------------------
Rv3596c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00235|M.leprae_Br4923          --------------------------------------------------
MMAR_5100|M.marinum_M               --------------------------------------------------
MUL_4178|M.ulcerans_Agy99           --------------------------------------------------
MAV_0556|M.avium_104                --------------------------------------------------
Mflv_1430|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5358|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0546|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_6091|M.smegmatis_MC2_155      --------------------------------------------------
TH_2346|M.thermoresistible__bu      MPGVAAATSTLFSPPELNLPSIPGVGIPLPNRLSLPTDGICEGLGWSAGK
                                                                                      

Mb3627c|M.bovis_AF2122/97           -----------------------
Rv3596c|M.tuberculosis_H37Rv        -----------------------
MLBr_00235|M.leprae_Br4923          -----------------------
MMAR_5100|M.marinum_M               -----------------------
MUL_4178|M.ulcerans_Agy99           -----------------------
MAV_0556|M.avium_104                -----------------------
Mflv_1430|M.gilvum_PYR-GCK          -----------------------
Mvan_5358|M.vanbaalenii_PYR-1       -----------------------
MAB_0546|M.abscessus_ATCC_1997      -----------------------
MSMEG_6091|M.smegmatis_MC2_155      -----------------------
TH_2346|M.thermoresistible__bu      SDGQGAEVPAAPVPADRRDRWDR