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FERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQ QAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQL LSGYQGKETAEAGTGGRGGEAGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNN PVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGD IILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPT VEHTIEILKGLRDRYEAHHRVSITDSALVAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPDL REFDEKIADARREKESAIDAQDFEKAASLRDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNW TGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTE LSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAH QEIYNSLLQVLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVHDEL KKHFRPEFLNRIDDIIVFHQLTQDEIIKMVDLMIGRVSKQLAAKDMTMELTDKAKSLLAKRGFDPVLGAR PLRRTIQREIEDQLSEKILFEEVGPGQLVTVDVEGWDGEGAGEDAKFTFIGTKKPVKIEEPDLAQAGAAG GPSAAE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5358 | - | - | 100% (847) | ATPase |
| M. vanbaalenii PYR-1 | Mvan_0659 | - | 0.0 | 46.59% (865) | ATPase |
| M. vanbaalenii PYR-1 | Mvan_2497 | - | 9e-20 | 37.41% (147) | Clp N terminal domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3627c | clpC | 0.0 | 94.81% (848) | ATP-dependent Clp protease ATP-binding subunit CLPC |
| M. gilvum PYR-GCK | Mflv_1430 | - | 0.0 | 96.81% (847) | ATPase |
| M. tuberculosis H37Rv | Rv3596c | clpC1 | 0.0 | 94.81% (848) | ATP-dependent protease ATP-binding subunit ClpC1 |
| M. leprae Br4923 | MLBr_00235 | clpC | 0.0 | 94.46% (849) | putative ATP-dependent Clp protease |
| M. abscessus ATCC 19977 | MAB_0546 | - | 0.0 | 95.02% (843) | ATP-dependent Clp protease ATP-binding subunit |
| M. marinum M | MMAR_5100 | clpC1 | 0.0 | 96.00% (849) | ATP-dependent protease ATP-binding subunit ClpC1 |
| M. avium 104 | MAV_0556 | - | 0.0 | 95.84% (818) | negative regulator of genetic competence ClpC/mecB |
| M. smegmatis MC2 155 | MSMEG_6091 | - | 0.0 | 96.69% (845) | negative regulator of genetic competence ClpC/mecB |
| M. thermoresistible (build 8) | TH_2346 | clpC | 0.0 | 95.34% (816) | PROBABLE ATP-DEPENDENT PROTEASE ATP-BINDING SUBUNIT CLPC1 |
| M. ulcerans Agy99 | MUL_4178 | clpC1 | 0.0 | 95.65% (850) | ATP-dependent protease ATP-binding subunit ClpC1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3627c|M.bovis_AF2122/97 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
Rv3596c|M.tuberculosis_H37Rv MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
MLBr_00235|M.leprae_Br4923 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLD
MMAR_5100|M.marinum_M MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
MUL_4178|M.ulcerans_Agy99 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
MAV_0556|M.avium_104 ---------------------MLNHNYIGTEHILLGLIHEGEGVAAKSLE
Mvan_5358|M.vanbaalenii_PYR-1 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
Mflv_1430|M.gilvum_PYR-GCK MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
MAB_0546|M.abscessus_ATCC_1997 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
MSMEG_6091|M.smegmatis_MC2_155 MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
TH_2346|M.thermoresistible__bu MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLE
****************************:
Mb3627c|M.bovis_AF2122/97 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
Rv3596c|M.tuberculosis_H37Rv SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
MLBr_00235|M.leprae_Br4923 SLGISLEAVRSQVEDIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
MMAR_5100|M.marinum_M SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
MUL_4178|M.ulcerans_Agy99 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
MAV_0556|M.avium_104 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
Mvan_5358|M.vanbaalenii_PYR-1 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
Mflv_1430|M.gilvum_PYR-GCK SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
MAB_0546|M.abscessus_ATCC_1997 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
MSMEG_6091|M.smegmatis_MC2_155 SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
TH_2346|M.thermoresistible__bu SLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGH
*******.******:***********************************
Mb3627c|M.bovis_AF2122/97 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
Rv3596c|M.tuberculosis_H37Rv NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
MLBr_00235|M.leprae_Br4923 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
MMAR_5100|M.marinum_M NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
MUL_4178|M.ulcerans_Agy99 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
MAV_0556|M.avium_104 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
Mvan_5358|M.vanbaalenii_PYR-1 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKET
Mflv_1430|M.gilvum_PYR-GCK NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGRET
MAB_0546|M.abscessus_ATCC_1997 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKET
MSMEG_6091|M.smegmatis_MC2_155 NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
TH_2346|M.thermoresistible__bu NYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEA
***********************************************:*:
Mb3627c|M.bovis_AF2122/97 AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
Rv3596c|M.tuberculosis_H37Rv AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
MLBr_00235|M.leprae_Br4923 AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMESKLDPVIGREKEIERV
MMAR_5100|M.marinum_M AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
MUL_4178|M.ulcerans_Agy99 AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
MAV_0556|M.avium_104 AEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
Mvan_5358|M.vanbaalenii_PYR-1 AEAGTGGRGGEAGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
Mflv_1430|M.gilvum_PYR-GCK AEAGTGGRGGEAGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
MAB_0546|M.abscessus_ATCC_1997 AESGTGGRGGEAGTPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
MSMEG_6091|M.smegmatis_MC2_155 AEAGTGGRGGESGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERV
TH_2346|M.thermoresistible__bu AEAGTGGRGGESGNPSTSLVLDQFGRNLTQAAAEGKLDPVIGREKEVERI
**:********:*.*************** ** *.***********:**:
Mb3627c|M.bovis_AF2122/97 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
Rv3596c|M.tuberculosis_H37Rv MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
MLBr_00235|M.leprae_Br4923 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
MMAR_5100|M.marinum_M MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
MUL_4178|M.ulcerans_Agy99 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
MAV_0556|M.avium_104 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGQVPETLKDKQLYTL
Mvan_5358|M.vanbaalenii_PYR-1 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
Mflv_1430|M.gilvum_PYR-GCK MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGDVPETLKDKQLYTL
MAB_0546|M.abscessus_ATCC_1997 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKNKQLYTL
MSMEG_6091|M.smegmatis_MC2_155 MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTL
TH_2346|M.thermoresistible__bu MQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVAGEVPETLKDKQLYTL
********************************** *:******:******
Mb3627c|M.bovis_AF2122/97 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
Rv3596c|M.tuberculosis_H37Rv DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
MLBr_00235|M.leprae_Br4923 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
MMAR_5100|M.marinum_M DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
MUL_4178|M.ulcerans_Agy99 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
MAV_0556|M.avium_104 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
Mvan_5358|M.vanbaalenii_PYR-1 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
Mflv_1430|M.gilvum_PYR-GCK DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
MAB_0546|M.abscessus_ATCC_1997 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
MSMEG_6091|M.smegmatis_MC2_155 DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
TH_2346|M.thermoresistible__bu DLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
**************************************************
Mb3627c|M.bovis_AF2122/97 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
Rv3596c|M.tuberculosis_H37Rv AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
MLBr_00235|M.leprae_Br4923 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
MMAR_5100|M.marinum_M AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
MUL_4178|M.ulcerans_Agy99 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
MAV_0556|M.avium_104 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
Mvan_5358|M.vanbaalenii_PYR-1 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
Mflv_1430|M.gilvum_PYR-GCK AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
MAB_0546|M.abscessus_ATCC_1997 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
MSMEG_6091|M.smegmatis_MC2_155 AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
TH_2346|M.thermoresistible__bu AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEP
**************************************************
Mb3627c|M.bovis_AF2122/97 TVEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAI
Rv3596c|M.tuberculosis_H37Rv TVEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAI
MLBr_00235|M.leprae_Br4923 TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI
MMAR_5100|M.marinum_M TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI
MUL_4178|M.ulcerans_Agy99 TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI
MAV_0556|M.avium_104 TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAI
Mvan_5358|M.vanbaalenii_PYR-1 TVEHTIEILKGLRDRYEAHHRVSITDSALVAAATLADRYINDRFLPDKAI
Mflv_1430|M.gilvum_PYR-GCK TVAHTIEILKGLRDRYEAHHRVSITDGAIAAAATLADRYINDRFLPDKAI
MAB_0546|M.abscessus_ATCC_1997 TVEHTIEILKGLRDRYEAHHRVSITDGALVAAATLADRYINDRFLPDKAI
MSMEG_6091|M.smegmatis_MC2_155 TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI
TH_2346|M.thermoresistible__bu TVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAI
** ***********************.*:.*************:******
Mb3627c|M.bovis_AF2122/97 DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL
Rv3596c|M.tuberculosis_H37Rv DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL
MLBr_00235|M.leprae_Br4923 DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL
MMAR_5100|M.marinum_M DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL
MUL_4178|M.ulcerans_Agy99 DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL
MAV_0556|M.avium_104 DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASL
Mvan_5358|M.vanbaalenii_PYR-1 DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL
Mflv_1430|M.gilvum_PYR-GCK DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASL
MAB_0546|M.abscessus_ATCC_1997 DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAARL
MSMEG_6091|M.smegmatis_MC2_155 DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAAAL
TH_2346|M.thermoresistible__bu DLIDEAGARMRIRRMTAPPDLREFDEKIAETRREKESAIDAQDFEKAAAL
*****************************::***************** *
Mb3627c|M.bovis_AF2122/97 RDREKTLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
Rv3596c|M.tuberculosis_H37Rv RDREKTLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
MLBr_00235|M.leprae_Br4923 RDREKQLVAQRAEREKQWRSGDLDVIAEVDDEQIAEVLGNWTGIPVFKLT
MMAR_5100|M.marinum_M RDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
MUL_4178|M.ulcerans_Agy99 RDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
MAV_0556|M.avium_104 RDREKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
Mvan_5358|M.vanbaalenii_PYR-1 RDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
Mflv_1430|M.gilvum_PYR-GCK RDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
MAB_0546|M.abscessus_ATCC_1997 RDSEKQLVAQRADREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
MSMEG_6091|M.smegmatis_MC2_155 RDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
TH_2346|M.thermoresistible__bu RDQEKQLVAQRAEREKQWRAGDLDVVAEVDDEQIAEVLGNWTGIPVFKLT
** ** ******:******:*****:************************
Mb3627c|M.bovis_AF2122/97 EAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
Rv3596c|M.tuberculosis_H37Rv EAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
MLBr_00235|M.leprae_Br4923 EAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
MMAR_5100|M.marinum_M EAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
MUL_4178|M.ulcerans_Agy99 EAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
MAV_0556|M.avium_104 EAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
Mvan_5358|M.vanbaalenii_PYR-1 EEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
Mflv_1430|M.gilvum_PYR-GCK EEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
MAB_0546|M.abscessus_ATCC_1997 EEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPRRPSGSFI
MSMEG_6091|M.smegmatis_MC2_155 EEETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFI
TH_2346|M.thermoresistible__bu EAETTRLLRMEEELHKRIIGQEDAVRAVSKAIRRTRAGLKDPKRPSGSFI
* *********:*************:****************:*******
Mb3627c|M.bovis_AF2122/97 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
Rv3596c|M.tuberculosis_H37Rv FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
MLBr_00235|M.leprae_Br4923 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
MMAR_5100|M.marinum_M FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
MUL_4178|M.ulcerans_Agy99 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
MAV_0556|M.avium_104 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
Mvan_5358|M.vanbaalenii_PYR-1 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
Mflv_1430|M.gilvum_PYR-GCK FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
MAB_0546|M.abscessus_ATCC_1997 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
MSMEG_6091|M.smegmatis_MC2_155 FAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
TH_2346|M.thermoresistible__bu FAGPSGVGKTELSKALAEFLFGDEDALIQIDMGEYHDRFTASRLFGAPPG
*****************:*****:**********:***************
Mb3627c|M.bovis_AF2122/97 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
Rv3596c|M.tuberculosis_H37Rv YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
MLBr_00235|M.leprae_Br4923 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
MMAR_5100|M.marinum_M YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
MUL_4178|M.ulcerans_Agy99 YVGYEEGGQLTEKVRRKPFSVALFDEIEKAHQEISNSLLQVLEDGRLTDG
MAV_0556|M.avium_104 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
Mvan_5358|M.vanbaalenii_PYR-1 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
Mflv_1430|M.gilvum_PYR-GCK YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
MAB_0546|M.abscessus_ATCC_1997 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQVLEDGRLTDG
MSMEG_6091|M.smegmatis_MC2_155 YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDG
TH_2346|M.thermoresistible__bu YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQVLEDGRLTDG
*********************.************ *:*************
Mb3627c|M.bovis_AF2122/97 QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSKGGGENDYERMKQKVNDE
Rv3596c|M.tuberculosis_H37Rv QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSKGGGENDYERMKQKVNDE
MLBr_00235|M.leprae_Br4923 QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGSGENDYERMKQKVNDE
MMAR_5100|M.marinum_M QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSQTGGENDYERMKQKVNDE
MUL_4178|M.ulcerans_Agy99 QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSQTGGENDYERMKQKVNDE
MAV_0556|M.avium_104 QGRTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGGGENNYERMKQKVNDE
Mvan_5358|M.vanbaalenii_PYR-1 QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVHDE
Mflv_1430|M.gilvum_PYR-GCK QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVHDE
MAB_0546|M.abscessus_ATCC_1997 QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSEGAAGSNYERMKQKVHDE
MSMEG_6091|M.smegmatis_MC2_155 QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSQGGSENNYERMKQKVHDE
TH_2346|M.thermoresistible__bu QGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSQGGSENNYERMKQKVHDE
*************************.*****:: .. .:********:**
Mb3627c|M.bovis_AF2122/97 LKKHFRPEFLNRIDDIIVFHQLTREEIIRMVDLMISRVAGQLKS-KDMAL
Rv3596c|M.tuberculosis_H37Rv LKKHFRPEFLNRIDDIIVFHQLTREEIIRMVDLMISRVAGQLKS-KDMAL
MLBr_00235|M.leprae_Br4923 LKKHFRPEFLNRIDDIIVFHQLSRDEIIRMVDLMISRVANQLKV-KDMTL
MMAR_5100|M.marinum_M LKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMIGRVANQLKS-KDMAL
MUL_4178|M.ulcerans_Agy99 LKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMIGRVANQLKSSKDMAL
MAV_0556|M.avium_104 LKKHFRPEFLNRIDDIIVFHQLTRDEIIRMVDLMITRVAGQLKS-KDMDL
Mvan_5358|M.vanbaalenii_PYR-1 LKKHFRPEFLNRIDDIIVFHQLTQDEIIKMVDLMIGRVSKQLAA-KDMTM
Mflv_1430|M.gilvum_PYR-GCK LKKHFRPEFLNRIDDIIVFHQLTQDEIIQMVDLMIGRVGNQLKA-KDMAM
MAB_0546|M.abscessus_ATCC_1997 LKKHFRPEFLNRIDDIIVFEQLTQEQIIEMVDLMIGRVGKQLKT-KDMAM
MSMEG_6091|M.smegmatis_MC2_155 LKKHFRPEFLNRIDDIIVFHQLTQDEIIQMVDLMIGRVSNQLKT-KDMAL
TH_2346|M.thermoresistible__bu LKKHFRPEFLNRIDDIIVFHQLTQEQIIQMVDLMIDRVRNQLKA-KDMDL
*******************.**::::**.****** ** ** *** :
Mb3627c|M.bovis_AF2122/97 VLTDAAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV
Rv3596c|M.tuberculosis_H37Rv VLTDAAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV
MLBr_00235|M.leprae_Br4923 ELTNKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV
MMAR_5100|M.marinum_M ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV
MUL_4178|M.ulcerans_Agy99 ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQV
MAV_0556|M.avium_104 VLTDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQI
Mvan_5358|M.vanbaalenii_PYR-1 ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQL
Mflv_1430|M.gilvum_PYR-GCK ELTPKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEELGPGQL
MAB_0546|M.abscessus_ATCC_1997 ELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDALSEKILFNEVGPGEL
MSMEG_6091|M.smegmatis_MC2_155 ELSDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEIGPGQL
TH_2346|M.thermoresistible__bu QLTDKAKQLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEELRPGQL
*: ** ************************** *******:*: **::
Mb3627c|M.bovis_AF2122/97 VTVDVDNWDGEGPGEDAVF-------------------------------
Rv3596c|M.tuberculosis_H37Rv VTVDVDNWDGEGPGEDAVF-------------------------------
MLBr_00235|M.leprae_Br4923 VTVDVDNWDGEGPGEDVKF-------------------------------
MMAR_5100|M.marinum_M VTVDVDNWDGEGAGEDAKF-------------------------------
MUL_4178|M.ulcerans_Agy99 VTVDVDNWDGEGAGEDAKF-------------------------------
MAV_0556|M.avium_104 VTVDVDNWDGESAGEDAVF-------------------------------
Mvan_5358|M.vanbaalenii_PYR-1 VTVDVEGWDGEGAGEDAKF-------------------------------
Mflv_1430|M.gilvum_PYR-GCK VTVDVENWDGEGQGEDAVF-------------------------------
MAB_0546|M.abscessus_ATCC_1997 VTVDVENWDGESAGEDAKF-------------------------------
MSMEG_6091|M.smegmatis_MC2_155 VTVDVEGWDGEGQGEDAKF-------------------------------
TH_2346|M.thermoresistible__bu ITVDVENWDGEGAGEDAXXXPTPPTGPAADVLNQATRVVPPAAPPSGTSA
:****:.****. ***.
Mb3627c|M.bovis_AF2122/97 --------------------TFTGTRKPPAEPDLAKAGAHSAGGPEPAAR
Rv3596c|M.tuberculosis_H37Rv --------------------TFTGTRKPPAEPDLAKAGAHSAGGPEPAAR
MLBr_00235|M.leprae_Br4923 --------------------TFTGIRKPSTEPDLAKAGVHSAGGPEPVEQ
MMAR_5100|M.marinum_M --------------------TFTGTRKPPSEPDLAKAGAHSAGGPGPTEQ
MUL_4178|M.ulcerans_Agy99 --------------------TFTGTRKPPSEPDLAKAGAHSAGGPGPTEQ
MAV_0556|M.avium_104 --------------------TFTGTRKPPAEPDLAKAGAHSADPQ-----
Mvan_5358|M.vanbaalenii_PYR-1 --------------------TFIGTKKPVKIEEPDLAQAGAAGGPSAAE-
Mflv_1430|M.gilvum_PYR-GCK --------------------TFSGARKPVEVAEPDLAQAGAGGAGPAAE-
MAB_0546|M.abscessus_ATCC_1997 --------------------TFVGRPKPALVAG---EEPAADLAASASE-
MSMEG_6091|M.smegmatis_MC2_155 --------------------TFSGGPKRAETAEPDLAGAGAAGAPTAGTE
TH_2346|M.thermoresistible__bu ARSGLLPSLLLPLQTTANTVTSVVPPPPPPAPGTPEAAVLETASGSASAA
*
Mb3627c|M.bovis_AF2122/97 --------------------------------------------------
Rv3596c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00235|M.leprae_Br4923 --------------------------------------------------
MMAR_5100|M.marinum_M --------------------------------------------------
MUL_4178|M.ulcerans_Agy99 --------------------------------------------------
MAV_0556|M.avium_104 --------------------------------------------------
Mvan_5358|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1430|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0546|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_6091|M.smegmatis_MC2_155 --------------------------------------------------
TH_2346|M.thermoresistible__bu MPGVAAATSTLFSPPELNLPSIPGVGIPLPNRLSLPTDGICEGLGWSAGK
Mb3627c|M.bovis_AF2122/97 -----------------------
Rv3596c|M.tuberculosis_H37Rv -----------------------
MLBr_00235|M.leprae_Br4923 -----------------------
MMAR_5100|M.marinum_M -----------------------
MUL_4178|M.ulcerans_Agy99 -----------------------
MAV_0556|M.avium_104 -----------------------
Mvan_5358|M.vanbaalenii_PYR-1 -----------------------
Mflv_1430|M.gilvum_PYR-GCK -----------------------
MAB_0546|M.abscessus_ATCC_1997 -----------------------
MSMEG_6091|M.smegmatis_MC2_155 -----------------------
TH_2346|M.thermoresistible__bu SDGQGAEVPAAPVPADRRDRWDR