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IDTAIEEMIPLIGVRAACAATGRAPASYYRAHSKRLSAQSDTFTSTAVTDPSGPRESAQPRALSAAEREH VLAVLNSQRFADMAPAVVYATLLDEGIYLCSESTMYRLLRERGQTGDRRRQATHPAAVKPELVAHQPNSV WSWDITKLRGPAKWSYYYLYVILDIFSRYVVGWMVASRESKVLAERLIAQTLAAQHISADQLTLHADRGS SMSSKPVALLLADLGVTKSHSRPHTSNDNPLSEAQFKTLKYRPDFPKRFESIEAARVHCDRFFGWYNHEH KHSGIGLHTPADVHYGRADQIRRHRATVLDTAYRDHLERIRSQTTRATRATGLQRDQPTTEGGPADSINP RKSCLRNVDRFRPGLLDLPAPAPVDLRRLLPSGQIR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3430c | - | - | 100% (387) | POSSIBLE TRANSPOSASE |
| M. tuberculosis H37Rv | Rv3475 | - | 5e-14 | 26.20% (271) | transposase IS6110 |
| M. tuberculosis H37Rv | Rv3380c | - | 5e-14 | 26.20% (271) | transposase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3460c | - | 0.0 | 99.74% (387) | transposase |
| M. gilvum PYR-GCK | Mflv_4078 | - | 7e-44 | 35.36% (280) | integrase catalytic subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2088 | - | 1e-10 | 26.40% (197) | transposase |
| M. marinum M | MMAR_3786 | - | 1e-07 | 24.62% (195) | transposase |
| M. avium 104 | MAV_1454 | - | 1e-12 | 30.05% (213) | transposase |
| M. smegmatis MC2 155 | MSMEG_1862 | - | 4e-73 | 53.15% (286) | transposase |
| M. thermoresistible (build 8) | TH_4372 | - | 3e-13 | 27.73% (220) | PUTATIVE Integrase, catalytic region |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0306 | - | 4e-45 | 35.02% (297) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2088|M.abscessus_ATCC_1997 ----------------------------MTRRVLKLARQPYYRWRANPIT
MMAR_3786|M.marinum_M ----MPRQYSSSVRRQIVSRLRVGEPVAVVAAETGVCQATLFRWKRQALI
Rv3430c|M.tuberculosis_H37Rv MIDTAIEEMIPLIGVRAACAATGRAPASYYRAHSKRLSAQSDTFTSTAVT
Mb3460c|M.bovis_AF2122/97 MIDTAIEEMIPLIGVRAACAATGRAPASYYRAHSKRLSAQSDTFTSTAVT
MSMEG_1862|M.smegmatis_MC2_155 -MDAYNDLRDIQIPTRKAAEVTG-----MHRSTATRRAKP-----APAPA
Mflv_4078|M.gilvum_PYR-GCK ------------MTAAIGSQRQALAMIDLSRSTWHYRTNP-----RPPVS
Mvan_0306|M.vanbaalenii_PYR-1 -------------------------MIELSRSTWHYRSHP-----RPRVA
TH_4372|M.thermoresistible__bu -----------VSRFELIAAECAHHDVSKLAELLGVSRSGYYAWAARQRR
MAV_1454|M.avium_104 ----------------------------MALSTYYDTKAR--------VP
MAB_2088|M.abscessus_ATCC_1997 DAELVEAYR--------------------------ANALFDAHGEDPEFG
MMAR_3786|M.marinum_M DAGVIEGTPSVEADELAAAHKRIAQLEAELALTRDACDLFNEEAVVPPKR
Rv3430c|M.tuberculosis_H37Rv DPSGPRESAQPR-----------------------ALSAAEREHVLAVLN
Mb3460c|M.bovis_AF2122/97 DPSGPRESAQPR-----------------------ALSAAEREHVLAVLN
MSMEG_1862|M.smegmatis_MC2_155 DR-APR-PVPVN-----------------------KLTESECARVVEVLN
Mflv_4078|M.gilvum_PYR-GCK DPLPQKHRAYPS-----------------------RIDEADRAVIRDKIL
Mvan_0306|M.vanbaalenii_PYR-1 NPMPHKDRAYPS-----------------------RIGVADRAVIAEQII
TH_4372|M.thermoresistible__bu VELSPRQQWRRD---------------------LEVKILAHWQASGRTYG
MAV_1454|M.avium_104 SARALRDAVLGP------------------------ALCQLWKDNYCVYG
.
MAB_2088|M.abscessus_ATCC_1997 YRYLVEEAREAG----------------------EPMAERTAWRICSQQQ
MMAR_3786|M.marinum_M RRAITEGLIARGHSARSACRVTGLARSLLQYHRRRLVPDREVRRLIVADT
Rv3430c|M.tuberculosis_H37Rv SQRFADMAPAVVY----------------------ATLLDEGIYLCSEST
Mb3460c|M.bovis_AF2122/97 SQRFADMAPAVVY----------------------ATLLDEGIYLCSEST
MSMEG_1862|M.smegmatis_MC2_155 SARFVDAAPMQVW----------------------ATLLDEGSYLCSVST
Mflv_4078|M.gilvum_PYR-GCK AGWEAGSSVDHAF----------------------AASWDEGVMLASRRS
Mvan_0306|M.vanbaalenii_PYR-1 AGWLAGVSVDQSF----------------------ATMWDAGVLLASRRS
TH_4372|M.thermoresistible__bu SPRITADLHAEGVG----------------------VSENTVAKIMAEMG
MAV_1454|M.avium_104 ARKLWKTARREGH----------------------DVGRDQVARLMRAAG
:
MAB_2088|M.abscessus_ATCC_1997 LWSVFGKKRGKNGKP-----------------------------------
MMAR_3786|M.marinum_M ITEIYQRSRGTYGRKRVRAALLADYDMNVNHKLVNSIMSEHGLYGLPRHG
Rv3430c|M.tuberculosis_H37Rv MYRLLRERGQTGDR------------------------------------
Mb3460c|M.bovis_AF2122/97 MYRLLRERGQTGDR------------------------------------
MSMEG_1862|M.smegmatis_MC2_155 MYRVLNANKLVKER------------------------------------
Mflv_4078|M.gilvum_PYR-GCK WWRIAAAIEDQSARPVAP--------------------------------
Mvan_0306|M.vanbaalenii_PYR-1 WWRIAAVI-DQSLRPVAP--------------------------------
TH_4372|M.thermoresistible__bu IEGISPRTFKVKTTQVDP--------------------------------
MAV_1454|M.avium_104 IEGVRRGKRVRTTKPD----------------------------------
:
MAB_2088|M.abscessus_ATCC_1997 -------GPPVHDDLVQRDFTAETPNMLWLSDITEHY--TGDGKLYLCAI
MMAR_3786|M.marinum_M RRKPNLIGVHTPVDLINRRFTATKPNELWCTDITEHP--ARDGKVYCCAI
Rv3430c|M.tuberculosis_H37Rv ------RRQATHPAAVKPELVAHQPNSVWSWDITKLRGPAKWSYYYLYVI
Mb3460c|M.bovis_AF2122/97 ------RRQATHPAAVKPELVAHQPNSVWSWDITKLRGPAKWSYYYLYVI
MSMEG_1862|M.smegmatis_MC2_155 ------RRLARHRKAVCPELVATAPRQVYSWDITKLAGPVKGVYYDAYVM
Mflv_4078|M.gilvum_PYR-GCK ------TRSTSKTPRQAPVLKATGPQQIWSWDITDLRSPWRGVAFKAYSI
Mvan_0306|M.vanbaalenii_PYR-1 ------TRATNKTPRSAPVLKATGPQQIWSWDITDLHSPWRGVSFKTYSI
TH_4372|M.thermoresistible__bu -------TASFPPDRVGRAFDQGRLDAVWTSDITYLT--CGEGDAYLCAI
MAV_1454|M.avium_104 ------PAAARHPDLVKRNFTATAPNQLWVTDLTFVP--TWAGVAYVCFI
: :: *:* :
MAB_2088|M.abscessus_ATCC_1997 KDAFSNRIVGYSIDSRMKSRLATAALRNAVGRRGVVAG-CVVHTDRGSQF
MMAR_3786|M.marinum_M LDCFSRMIVARTFSTTADTALVNNAVNMAVDHRNRSGP-TILHADHGTQF
Rv3430c|M.tuberculosis_H37Rv LDIFSRYVVGWMVASRESKVLAERLIAQTLAAQHISADQLTLHADRGSSM
Mb3460c|M.bovis_AF2122/97 LDIFSRYVVGWMVASRESKVLAERLIAQTLAAQHISADQLTLHADRGSSM
MSMEG_1862|M.smegmatis_MC2_155 IDIYSRYIVGVHVHARECGQLAKEMMEQIFGTYGIPH---VVHADRGTSM
Mflv_4078|M.gilvum_PYR-GCK LDIYSRKIVGWRVEERECDDLAVDMFEAAFAGHGLPA---VVHADSGPAM
Mvan_0306|M.vanbaalenii_PYR-1 VDIFSRKIVGWRVEERECDDLAVEMFKTAIAEHGPPA---VVHADSGPAM
TH_4372|M.thermoresistible__bu RDEHSRRVLGWSLADHMRTELVEAAVDAAVFTRAGHVAGTVMHSDRGSQF
MAV_1454|M.avium_104 IDAYSRMIVGWRVASHMRTSMVLDALEMARWSRGNMLPGLRCHSDAGSQF
* .*. ::. . :. . *:* *. :
MAB_2088|M.abscessus_ATCC_1997 RSRKFVQALHHHGMVGSMGRVGAAGDNAAMESF----FSLLQKNVLDRRR
MMAR_3786|M.marinum_M TSWSFGENMRRWGLLGSFGTVGDCFDNAAMESF----WARLQVELLNTRK
Rv3430c|M.tuberculosis_H37Rv SSKPVALLLADLGVTKSHSRPHTSNDNPLSEAQ----FKTLKYRPDFPKR
Mb3460c|M.bovis_AF2122/97 SSKPVALLLADLGVTKSHSHPHTSNDNPLSEAQ----FKTLKYRPDFPKR
MSMEG_1862|M.smegmatis_MC2_155 TSNTVAGLLSDLGVIRSHSRPKVSNDNPYSESW----FKTLKYAPAFPER
Mflv_4078|M.gilvum_PYR-GCK RSTVLKDLLAGLKIGQTHNRPRVSNDNPFSESE----FRTMKYRPNYPGV
Mvan_0306|M.vanbaalenii_PYR-1 RSTVLKDLLAGLGIGQTHIRPHVSNDNPFSESE----FRTMKYRPNYPGV
TH_4372|M.thermoresistible__bu TSYDMAQACTRHGLLRSMGATGICWDNAGSESL----WSTVKHEYYKRHA
MAV_1454|M.avium_104 TSIRYGERLAEIGAVPSIGTVGDSFDNALAETVNGYYKAELIYGPARTGP
* : . **. *: :
MAB_2088|M.abscessus_ATCC_1997 WATREELRIAIVTWIERTYHRRRRQGALGRLTPVEYEAIMTTTASQAA--
MMAR_3786|M.marinum_M WATTIELAAAMADYIDNFYNIERRHSYLGNISPTEFETLWTSTYSIPQLA
Rv3430c|M.tuberculosis_H37Rv FESIEAARVHCDRFFG-WYNHEHKHSGIGLHTPADVHYGRADQIRRHRAT
Mb3460c|M.bovis_AF2122/97 FESIEAARVHCDRFFG-WYNHEHKHSGIGLHTPADVHYGRADQIRRHRAT
MSMEG_1862|M.smegmatis_MC2_155 FESIHHARDFMDRFVQ-WYNHEHRHSGIGLHTPADVFYGLAGGKDTQRRA
Mflv_4078|M.gilvum_PYR-GCK FTDLDSARAWVSAYVS-WYNQHHRHSGVELFTPDSVHDGTWAQLWDRRDT
Mvan_0306|M.vanbaalenii_PYR-1 FDDLNTAHAWVQAYVR-WYNQHHRHSGIALFTPDEVHNGSWTRQWMHRDH
TH_4372|M.thermoresistible__bu FTTYANLTAGLDNYIR-FYNHERRHSSLGMISPIDFDLSLDILLSTQV--
MAV_1454|M.avium_104 WKTVEDVELATLSWVY-WHNTSRLHSYLGDIPPAEFEAAFYDAYRTDQPL
: :. :: : :. : .* .
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3786|M.marinum_M --------------------------------------------------
Rv3430c|M.tuberculosis_H37Rv VLDTAYRDHLERIRSQTTRATRATGLQRDQPTTEGGPADSINPRKSCLRN
Mb3460c|M.bovis_AF2122/97 VLDTAYRDHLERIRSQTTRATRATGLQRDQPTTEGGPADSINPRKSCLRN
MSMEG_1862|M.smegmatis_MC2_155 VLADARARHPRRFGRDT--APKVIDLP---------ESAAINPPK-----
Mflv_4078|M.gilvum_PYR-GCK ALQAYYDAHPERFRNRPRTKSPS-------------PVVGINLPT-----
Mvan_0306|M.vanbaalenii_PYR-1 ILQAYYHAHPERFRARPHTKSPA-------------AIVGINLPT-----
TH_4372|M.thermoresistible__bu --------------------------------------------------
MAV_1454|M.avium_104 IGIQ----------------------------------------------
MAB_2088|M.abscessus_ATCC_1997 -----------------------------
MMAR_3786|M.marinum_M -----------------------------
Rv3430c|M.tuberculosis_H37Rv VDRFRPGLLDLPAPAPVDLRRLLPSGQIR
Mb3460c|M.bovis_AF2122/97 VDRFRPGLLDLPAPAPVDLRRLLPSGQIR
MSMEG_1862|M.smegmatis_MC2_155 -----------PAEQETETEAA-------
Mflv_4078|M.gilvum_PYR-GCK ------------ENDPDRLQAA-------
Mvan_0306|M.vanbaalenii_PYR-1 ------------EKDPNRLHAA-------
TH_4372|M.thermoresistible__bu -----------------------------
MAV_1454|M.avium_104 -----------------------------